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Results 401 - 450 of 2244
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Crow Yanick J YJ INSERM UMR 1163, Laboratory of Neurogenetics and Neuroinflammation, Institut Imagine, Paris, - - 2014
Background Hereditary spastic paraplegia is a neurodegenerative phenotype characterized by a progressive loss of corticospinal motor tract function. In a majority of affected individuals the pathogenesis remains undetermined. Methods We identified a series of patients with a phenotype of nonsyndromic spastic paraplegia in whom no diagnosis had been reached before exome sequencing. ...
Fournier Jean-Pascal JP Centre for Clinical Epidemiology (Fournier, Yin, Yu, Azoulay), Lady Davis Institute, Jewish General Hospital; Department of Epidemiology, Biostatistics and Occupational Health (Fournier), McGill University; Division of Endocrinology (Yu), Jewish General Hospital; Department of Oncology (Azoulay), McGill University, Montréal, - - 2014
Small cross-sectional studies have suggested that metformin, a first-line oral hypoglycemic agent, may lower thyroid-stimulating hormone (TSH) levels. Our objective was to determine whether the use of metformin monotherapy, when compared with sulfonylurea monotherapy, is associated with an increased risk of low TSH levels (< 0.4 mIU/L) in patients with ...
Zandi Michael S MS Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge, UK National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, London, - - 2014
There are now a large number of requests for N-methyl-d-aspartate receptor autoantibody (NMDAR-Ab) tests, and it is important to assess the clinical relevance of all results, particularly when they are reported as 'Low Positive'. The clinical data of 56 patients found Positive or Low Positive by the Oxford live cell-based ...
Zhang Minfang M Renal Division, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, - - 2014
To investigate the prevalence of metabolic syndrome (MS) in patients with lupus nephritis (LN), and its correlation with carotid atherosclerosis. Two hundred ten patients with LN (age: 38.83 ± 12.41 years, 92.86% women) were enrolled. The control group included 150 lupus patients without nephritis and 200 age-matched healthy persons. The ...
Fotos Joseph S JS From the Section of Nuclear Medicine, Department of Radiology, Milton S. Hershey Medical Center, Penn State University, Hershey, - - 2014
Ventilation-perfusion scintigraphy is routinely performed in patients with suspected pulmonary thromboembolism. Pleural effusions in such patients are common and can cause matched ventilation-perfusion defects. This is especially true of the posterior projections in the supine patient. Prone positioning has been described as a useful technique to redistribute pleural fluid anteriorly, ...
Rana Surinder S SS Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh - 160012, - - 2014
Extra pancreatic necrosis (EPN) alone represents a subgroup of pancreatitis with better outcome than patients with pancreatic parenchymal necrosis (PN). However, data on clinical significance of EPN is limited and significance of extent of EPN is not known. 213 patients (136 (63.8%) males; mean age: 39.8 ± 13.2 years) with ...
Verma Himanshu H Narayana Institute of Vascular Sciences, Bangalore, - - 2014
Primary aortic mural thrombus (PAMT) is an uncommon condition but an important source of noncardiogenic emboli with a difficult diagnosis and a high rate of complications, including high mortality. We report our experience of thromboembolic disease from PAMT and review its contemporary management. Retrospective analysis of prospectively collected data of ...
He Yi - - 2014
Osteoarthritis (OA) is the most common degenerative joint disease, of which the pathogenesis is inadequately understood. Hypertrophy-like changes have been observed as part of the progression of OA. The aim of the study was to develop and characterize a novel biomarker of chondrocytes hypertrophy and investigate how this marker was ...
Han Xiaohong X Department of Medical Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing 100021, - - 2014
In this study, serum free and total light chains (sFLC/sTLC) were measured in 108 serum samples of therapy-naïve patients with DLBCL. Clinicopathologic data and survival outcomes were analyzed according to the results of sFLC/sTLC measurements. Moreover, the association of sFLC/sTLC with absolute monocyte count (AMC) and absolute lymphocyte count (ALC) ...
Lorente Leonardo L Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain. Electronic address: - - 2014
Total antioxidant capacity (TAC) in severe septic patients has been analyzed in few studies with limited number of subjects. In addition, no association between TAC serum levels and mortality in patients with sepsis has been investigated. We aimed at assessing a possible relationship between TAC serum levels and mortality using ...
Pokryszko-Dragan Anna A Department of Neurology, Medical University of Wroclaw, Borowska 213, 50-556, Wrocław, Poland, - - 2014
The aim of the study was to evaluate visual and brainstem auditory evoked potentials (VEP, BAEP) in multiple sclerosis (MS) patients with regards to fatigue and disease-related variables. The study comprised 86 MS patients and 40 controls. Fatigue was assessed using the Fatigue Severity Scale (FSS/FSS-5) and the Modified Fatigue ...
Pastore Serena S University of Trieste, Trieste, - - 2014
For children with juvenile idiopathic arthritis (JIA) who fail to respond to methotrexate, the delay in identifying the optimal treatment at an early stage of disease can lead to long-term joint damage. Recent studies indicate that relevant variants to predict methotrexate response in JIA are those in 5-aminoimidazole-4-carboxamide ribonucleotide-transformylase (ATIC), ...
Stallmach Andreas A Andreas Stallmach, Luisa Nickel, Martin Bürger, Carsten Schmidt, Klinik für Innere Medizin IV, Universitätsklinikum Jena, Jena 07747, - - 2014
To detect high risk patients with a progressive disease course of ulcerative colitis (UC) requiring immunosuppressive therapy (IT). A retrospective, multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed. Patients were divided into two groups depending on the patients need to initiate immunosuppressive ...
Zhang Fu-Bo FB Fu-Bo Zhang, Ai-Min Zhang, Zhi-Bin Zhang, Xin Huang, Xi-Tao Wang, Jia-Hong Dong, Department of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, - - 2014
To investigate preoperative differential diagnoses made between intrahepatic biliary cystadenoma and intrahepatic biliary cystadenocarcinoma. A retrospective analysis of patient data was performed, which included 21 cases of intrahepatic biliary cystadenoma and 25 cases of intrahepatic biliary cystadenocarcinoma diagnosed between April 2003 and April 2013 at the General Hospital of PLA. ...
Chen Yuanyuan Y Yuanyuan Chen, Eric M Yoshida, Division of Gastroenterology, University of British Columbia, Vancouver, BC V5Z 1M9, - - 2014
A case is presented of a 36-year-old male with primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD) and two synchronous stage 1 adenocarcinomata of the colon, who was initially treated with a subtotal colectomy with ileostomy. One year later, the patient presented with extensive intra-abdominal lymphadenopathy and peritoneal carcinomatosis, as well ...
Goliszek Sylwia S Dept. of Internal Medicine and Cardiology, Medical University of Warsaw, - - 2014
Patent foramen ovale (PFO) is an established risk factor for ischemic stroke. Since acute right ventricular dysfunction (RVD) observed in patients with PE can lead to right-to-left inter-atrial shunt via PFO, we hypothesized that PFO is a risk factor for ischemic stroke in PE with significant right ventricular dysfunction. 55 ...
Garin Eduardo H EH Division of Pediatric Nephrology, Department of Pediatrics, University of Florida, 1600 SW Archer Rd., HD214, Gainesville, FL, 32610, USA, - - 2014
Minimal Change Disease (MCD) in relapse is associated with increased podocyte CD80 expression and elevated urinary CD80 excretion, whereas focal segmental glomerulosclerosis (FSGS) has mild or absent CD80 podocyte expression and normal urinary CD80 excretion. One patient with MCD, one patient with primary FSGS and three patients with recurrent FSGS ...
Tanaka Atsushi A Department of Medicine, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan, - - 2014
Bezafibrate is reported to have biochemical efficacy for patients with primary biliary cirrhosis (PBC) refractory to ursodeoxycholic acid (UDCA), yet the long-term effect is still unknown. In Japan, nationwide surveys of PBC have been performed since 1980. In the current study, we retrospectively examined whether response to bezafibrate treatment is ...
Tien Connie C Asian Pacific Liver Center, Saint Vincent Medical Center, Los Angeles, CA, - - 2014
Increased risk of defective urinary phosphate reabsorption and osteoporosis has been reported in HIV and chronic hepatitis B (CHB) patients treated with tenofovir disoproxil fumarate (TDF). Goals of this study were to evaluate the prevalence of renal phosphate wasting and abnormal bone mineral density in CHB patients taking TDF compared ...
Ogawa Satoshi S International University of Health and Welfare Mita Hospital, Tokyo, Japan. Electronic address: - - 2014
The postmarketing surveillance registry evaluated the safety and efficacy of rivaroxaban in Japanese patients with atrial fibrillation (AF) treated with rivaroxaban. A total of 10,038 patients with AF were enrolled between April 18, 2012 and December 16, 2013. Overall, 48.9% of the patients were of 75 years or older. The median ...
Nabih Mona I MI Department of Internal Medicine, Cairo University, Giza, Egypt. Electronic address: - - 2014
Alfa fetoprotein (AFP) is widely used as a surveillance test for hepatocellular carcinoma (HCC) among patients with liver cirrhosis (LC). However, the clinical use of AFP has been shown to present some important limitations in sensitivity and specificity. Osteopontin (OPN) is a secreted matrix glycoprotein that is emerging as a ...
El Bokl Mohamed A MA Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, - - 2014
Liver cirrhosis leads to decreased production of clotting factors that are generally all produced in the liver except factor VIII and von Willebrand factor. However, cirrhotic patients are not protected from thrombosis. The present study aimed to assess the procoagulant and anticoagulant factors in cirrhotic patients with and without bleeding ...
Khorana Alok A AA Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. Electronic address: - - 2014
The utility of screening for venous thromboembolism (VTE) in cancer patients is unknown. We evaluated this in a prospective cohort study of cancer patients initiating a new chemotherapy regimen and deemed high-risk (score ≥3) based on a validated Risk Score. Patients were evaluated with baseline and Q4 (±1) week serial ...
Di Carlo G G Department of Oral and Maxillofacial Science, Pediatric Dentistry Unit, Sapienza University of Rome, Rome, Italy; Section of Orthodontics, Department of Dentistry, Health, Aarhus University, Aarhus, - - 2014
To assess whether morphology and dimension of the upper airway differ between patients characterized by various craniofacial morphology. Ninety young adult patients from the Postgraduate Clinic, Section of Orthodontics, Department of Dentistry, Health, Aarhus University, Denmark, with no obvious signs of respiratory diseases and no previous adeno-tonsillectomy procedures. Thirty patients ...
Ylmaz Bülent B aDepartment of Gastroenterology, Izzet Baysal State Hospital bDepartment of Gastroenterology, Abant Izzet Baysal University School of Medicine, Bolu Departments of cInternal Medicine dGastroenterology, Kocaeli University School of Medicine, Kocaeli, Turkey eCleveland Clinic, Department of Pathobiology, Cleveland, Ohio, - - 2014
Neutrophil-lymphocyte ratio (NLR) has been used as a simple, affordable, and easily accessible marker to predict prognosis in a variety of inflammatory and neoplastic diseases. However, there are few studies investigating their role in patients with hepatitis B. The aim of this study was to investigate the relationship between NLR ...
Ito-Yamaguchi Akiko A Department of Obstetrics and Gynecology, Fukushima Medical University , Fukushima , Japan - - 2014
Abstract Objective: To evaluate effects of metformin on endocrine, metabolic parameters and endometrial androgen receptor (AR) expression in polycystic ovary syndrome (PCOS). Design: Prospective observational study. Methods: We analyzed blood samples from 10 PCOS patients, of whom endometrium was also analyzed in five patients. Before and after three months of ...
Pfeifer Charlotte D CD Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, - - 2014
To determine the pancreatic iron (R2*) and fat content (FC) in comparison to hepatic and cardiac R2* in patients with iron overload disorders like β-thalassemia major (TM), Diamond-Blackfan anemia (DBA) or hereditary hemochromatosis. R2* rates were assessed in the liver, heart and pancreas of 42 patients with TM, 29 subjects ...
Madre Merce M FIDMAG Research Foundation Germanes Hospitaláries Barcelona, Barcelona, Spain; Departament de Psiquiatria i Medicina Legal, Doctorat de Psiquiatria i, Psicologia Clínica, Universitat Autònoma de Barcelona, Barcelona, Spain; Division of Psychiatry, University College of London, London, - - 2014
Schizoaffective patients can have neurocognitive deficits and default mode network dysfunction while being acutely ill. It remains unclear to what extent these abnormalities persist when they go into clinical remission. Memory and executive function were tested in 22 acutely ill schizoaffective patients; they also underwent fMRI scanning during performance of ...
Arnason Thomas T 1] Gastrointestinal Pathology Service, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA [2] Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS, - - 2014
Collagenous gastritis is a rare condition defined histologically by a superficial subepithelial collagen layer. This study further characterizes the morphologic spectrum of collagenous gastritis by evaluating a multi-institutional series of 40 patients (26 female and 14 male). The median age at onset was 16 years (range 3-89 years), including 24 ...
Migita Kiyoshi K Department of Rheumatology and Clinical Research Center, Nagasaki Medical Center, Omura, Department of Rheumatology, Isahaya Health Insurance General Hospital, Nagasaki, Department of Infection and Host Defense, Graduate School of Medicine, Shinshu University, Matsumoto, Department of Pathology, Ehime University Graduate School of Medicine and Proteo-Science Center, Ehime, Department of Rheumatology, Sasebo City General Hospital, Sasebo, Department of Rheumatology, Shinto Kumamoto Hospital, Kumamoto, Clinical Research Center, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Institute of Tropical Medicine (NEKKEN), Nagasaki University and Department of Rheumatology, Nagasaki University Hospital, Nagasaki, Japan. - - 2014
The aim of this study was to analyse the role of circulating cleaved IL-1β in patients with FMF. We enrolled 20 patients with FMF (5 males and 15 females), 22 patients with RA (4 males and 18 females) and 22 healthy controls (6 males and 16 females). Serum levels of ...
Kopylov Uri U Division of Gastroenterology, McGill University Health Centre, Montreal, QC, Canada, - - 2014
Clinical efficacy and risk of complications are associated with intracellular levels of thiopurine metabolites 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurines (6-MMP) in patients with Crohn's disease. Therapeutic monitoring of thiopurine metabolites is not widely available. Surrogate markers such as hematologic indices (MCV, leukopenia) have been proposed. To evaluate accuracy of hematologic ...
Gurses Kadri Murat KM Department of Cardiology, Hacettepe University Faculty of Medicine, 06100 Ankara, - - 2014
Atrial fibrosis has been found to be associated with recurrent atrial fibrillation (AF) following catheter ablation. Autoantibodies against M2-muscarinic receptors (anti-M2-R) may play a role in the development of AF by inducing left atrial (LA) fibrosis. In this study, we aim to compare anti-M2-R levels between paroxysmal lone AF patients ...
Maejima Nobuhiko N Division of Cardiology, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, - - 2014
We sought to compare the morphological features of non-culprit plaques with >50% diameter stenosis in patients with acute coronary syndromes (ACS) with those of culprit plaques in patients with ACS and stable angina pectoris (SAP) using optical coherence tomography (OCT) and integrated backscatter intravascular ultrasound (IB-IVUS). A total of 150 ...
Corredor Zuray Z Grup de Mutagènesi, Departament de Genètica i de Microbiologia, Edifici C, Universitat Autònoma de Barcelona, 08193, Bellaterra, Cerdanyola del Vallès, - - 2014
Patients suffering from chronic kidney disease (CKD) exhibit a high incidence of cancer and cardiovascular diseases, as well as high levels of genomic damage. To confirm the association of CKD with genomic damage we have carried out the largest study to date addressing this issue, using a total of 602 ...
Verhoeven E E Department of Intensive Care, Cliniques St-Luc, Université catholique de Louvain , Brussels , - - 2014
A 55-year-old man was admitted after a suspected hypnotic overdose of valerian extracts. In addition to altered consciousness, the first clinical symptoms included not only diffuse rash on the face, trunk, and limbs, but also an inspiratory dyspnea with a marked hypoxemia. A major laryngeal edema was noted during orotracheal ...
Debono Miguel M Academic Unit of Endocrinology, Department of Human Metabolism, University of Sheffield, Sheffield, UK (MD, RJR, JN-P); Medical Statistics and Clinical Trials Research Unit, The School of Health and Related Research, University of Sheffield, Sheffield, UK (MBr); The Departments of Endocrinology (MD, RJR, JN-P), Radiology (MBu) and Endocrine Surgery (BH), Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, - - 2014
Context: Incidental benign adrenocortical adenomas, 'adrenal incidentalomas', are found in 4.5% of abdominal CT scans, with the incidence increasing to 10% in patients over 70 years. These incidentalomas frequently show evidence of excess cortisol secretion but without overt Cushing's syndrome. The mortality rate is increased in Cushing's syndrome. Objective: To ...
Tanida Satoshi S Nagoya City University Graduate School of Medical Sciences, Aichi, - - 2014
& Aims: Behçet's disease is a chronic, relapsing inflammatory disease that can involve the mouth, skin, eyes, genitals, and intestines. Active intestinal Behçet's disease can be complicated by gastrointestinal (GI) bleeding and perforation. We performed a multicenter, open-label, uncontrolled study to evaluate the efficacy and safety of adalimumab, a fully ...
Chevalier-Bidaud Brigitte - - 2014
ATS/ERS Task Force has highlighted that special attention must be paid when FEV1 and FVC are concomitantly decreased (<5th percentile) and the FEV1/FVC ratio is normal (>5th percentile) because a possible cause of this non specific pattern (NSP) is collapse of small airways with normal TLC measured by body plethysmography ...
Sibila Oriol O Department of Respiratory Medicine, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomédica Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona, Department of Medicine, Barcelona Respiratory Network (BRN), Barcelona, Spain. Electronic address: - - 2014
Airway bacterial colonization by potentially pathogenic microorganisms occurs in a proportion of patients with Chronic Obstructive Pulmonary Disease (COPD). It increases airway inflammation and influences outcomes negatively. Yet, its diagnosis in clinical practice is not straightforward. The electronic nose is a new non-invasive technology capable of distinguishing volatile organic compound ...
Song Xueqin X The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China. Electronic address: - - 2014
This study was to examine cortical thickness in drug naïve, first episode schizophrenia patients, and to explore its relationship with serum levels of brain-derived neurotrophic factor (BDNF). Forty-five drug naive schizophrenia patients and 28 healthy controls were enrolled in the study. Freesurfer was used to parcellate cortical regions, and vertex-wise ...
Barbieri L L Division of Cardiology, Azienda Ospedaliera-Universitaria "Maggiore della Carità", Eastern Piedmont University, Novara, - - 2014
Contrast Induced Nephropathy (CIN) is a common complication of procedures that require the use of contrast media, and seems to be mediated by oxidative stress and reactive oxygen species generation. Hyperuricemia is characterized by inhibited nitric oxide system and enhanced synthesis of reactive oxygen species. However, few studies have so ...
Park Young Min YM Department of Otorhinolaryngology, Pundang Jesaeng Hospital, Deajin Medical Center, Seongnam, Gyeonggi, - - 2014
We investigated extrathyroidal extension (ETE) through frozen biopsy for intraoperative decision making in patients with papillary thyroid cancer (PTC). During the period of the study an operation was performed in 268 patients with PTC and ETE was evaluated using intraoperative frozen biopsies of thyroid tissue. Extrathyroidal extension was confirmed in ...
Paudel Klara K Department of Renal Medicine and Transplantation, Barts Health NHS Trust, London, - - 2014
Bioimpedance spectroscopy (BIS), ultrasound of lungs (lung ultrasound comets: LUC) and serum biomarkers (N-Terminal pro-brain natriuretic peptide, NT-proBNP) have been used to assist clinicians to determine hydration status in dialysis patients. But how do they compare? We performed simultaneous measurements of BIS, LUC and NT-proBNP in 27 peritoneal dialysis patients ...
Matsuda Shunichi S Department of Neurology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, - - 2014
The aim of paper was to investigate abnormalities in visual scanning using an eye-tracking device with patients with spinocerebellar ataxia type 6 (SCA6) and SCA31, pure cerebellar types of spinocerebellar degeneration. Nineteen SCA patients (12 patients with SCA6 and 7 patients with SCA31) and 19 normal subjects in total participated ...
Terashi Hiroo H aDepartments of - - 2014
Abstract Background: There is a need to define the basic characteristics of various kinematic parameters recorded during walking in patients with vascular parkinsonism (VP). The present study was designed to determine the kinematic features of walking in VP patients. For this purpose, gait acceleration and cycle were recorded continuously over ...
Celikoglu Mevlut M a Associate Professor, Department of Orthodontics, Faculty of Dentistry, Akdeniz University, Antalya, - - 2014
Objective: To evaluate the mandibular dental, alveolar, and skeletal transversal widths in patients affected by unilateral (UCLP) and bilateral (BCLP) cleft lip and palate and to compare the findings with a well-matched normal occlusion sample using cone beam computed tomography images. Materials and Methods: The study sample consisted of 75 ...
Siler Dominic A DA Department of Anesthesiology & Perioperative Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, - - 2014
Patients recovering from aneurysmal subarachnoid hemorrhage (SAH) are at risk for developing delayed cerebral ischemia (DCI). Experimental and human studies implicate the vasoconstrictor P450 eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE) in the pathogenesis of DCI. To date, no studies have evaluated the role of vasodilator epoxyeicosatrienoic acids (EETs) in DCI. Using mass ...
Hirashio Shuma S Department of Nephrology, Hiroshima University Hospital, Hiroshima, - - 2014
Telomeric G-tails play a pivotal role in maintaining the intramolecular loop structure of telomeres. Previous in vitro studies have suggested that the erosion of telomeric G-tails triggers cellular senescence, leading to organ dysfunction and atherosclerosis. The authors recently established a method to measure telomeric G-tail length using a hybridization protection ...
Olesen Jonas Bjerring JB Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark Department of Cardiology, Copenhagen University Hospital Hvidovre, Kettegård Allé 30, 2650 Hvidovre, Denmark - - 2014
Non-vitamin K antagonist oral anticoagulation (NOAC) agents have been approved for stroke prophylaxis in atrial fibrillation (AF). We investigated 'real-world' information on how these drugs are being adopted. Using Danish nationwide administrative registers, we identified all oral anticoagulation-naïve AF patients initiating oral anticoagulation from 22 August 2011 through 31 October ...
Miyake T T Departments of Dermatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, - - 2014
Epstein-Barr virus (EBV)-associated T/NK lymphoproliferative disorders are a group of diseases that include classical and systemic hydroa vacciniforme (HV), and hypersensitivity to mosquito bites (HMB). Patients with systemic HV (sHV) and HMB often have a poor prognosis, although little is known about the prognostic factors. In order to elucidate the ...
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