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Results 401 - 450 of 3379
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Lee J J Department of Internal Medicine, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Jung-Gu, Daegu, 700-842, Republic of - - 2014
Tuberculous pleural effusion (TPE) is characterized by lymphocytic predominance and high adenosine deaminase (ADA) levels. However, TPEs sometimes present non-lymphocytic predominance, and parapneumonic effusion (PPE) often exceeds the cutoff value of ADA for TPE. Thus, the differential diagnosis of cases with pleural fluid (PF) showing non-lymphocytic predominance and high ADA ...
Miah Chowdhury F CF Departments of Surgery and Radiology, Rutgers Robert Wood Johnson, New Brunswick, - - 2014
The American Thyroid Association recommends lymph node mapping (LNM) ultrasonography 6-12 months after thyroidectomy for patients with papillary thyroid cancer (PTC). The yield of LNM over thyroglobulin (TG) screening is not well defined. We sought to investigate this relationship. Post thyroidectomy LNM was performed on 163 patients with PTC. LNM was ...
Stiver Corey C The Heart Center, Nationwide Children's Hospital, Columbus, Ohio, - - 2014
Diastolic dyssynchrony is increasingly being recognized as another marker for possible adverse cardiac events. Minimal data exist in hypoplastic left heart syndrome (HLHS) patients. The goal of this study was to determine if there were differences in diastolic dyssynchrony in patients with HLHS vs. control patients. Tissue Doppler imaging (TDI) ...
Correa-Gallego Camilo C Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2014
Low central venous pressure (LCVP)-assisted hepatectomy is associated with decreased blood loss and lower transfusion rates. Concerns about its impact on renal function have prevented widespread application. This study was conducted to review the dynamics of renal function after LCVP-assisted hepatectomy. A retrospective analysis of a prospective surgical database was ...
Krogias Christos C Department of Neurology, Ruhr University Bochum St. Josef-Hospital, Gudrunstr. 56, 44791, Bochum, Germany, - - 2014
Myotonic dystrophies (DMs) are clinically similar but distinct multisystemic diseases related to different repeat expansion mutations. CNS involvement is one important aspect of both, myotonic dystrophy type 1 and type 2 (DM1, DM2). Transcran ial sonography (TCS) has become a reliable diagnostic tool in the evaluation of several CNS disorders. ...
Aronova Anna A Department of Surgery, Weill Cornell Medical College/New York Presbyterian Hospital, New York, - - 2014
The Aldosteronoma Resolution Score (ARS) takes into consideration four, readily available, preoperative clinical parameters in predicting the likelihood of resolution of hypertension in patients 6 months after undergoing unilateral adrenalectomy for aldosterone-producing adenoma (APA). We sought to determine the durability of this predictive model after 1 year. Sixty patients who underwent unilateral ...
Zilberberg Eran E Department of Obstetrics and Gynecology, Chaim Sheba Medical Center - Tel Hashomer , Ramat Gan , Israel - - 2014
Abstract Objective: Human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH), as a surrogate LH surge, to induce final oocyte maturation and resumption of meiosis. Recently, the co-administration of GnRH agonist and hCG for final oocyte maturation - 40 and 34 h prior to OPU, ...
Hua Jing J Key laboratory of Gastroenterology & Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive - - 2014
We aimed to evaluate the efficacy of liver stiffness measurement (LSM) in predicting the presence and severity of esophgeal varices (EV) and its association with liver function in patients with liver cirrhosis. Medical records of 90 cirrhotic patients who underwent LSM by transient elastography were retrospectively reviewed. The relationship between ...
Tilan Jason U JU Department of Nursing, School of Nursing and Health Studies, Georgetown University, Washington, District of Columbia; Department of Human Science, School of Nursing and Health Studies, Georgetown University, Washington, District of - - 2014
Ewing sarcoma (ES) is driven by fusion of the Ewing sarcoma breakpoint region 1 gene (EWSR1) with an E26 transformation-specific (ETS) transcription factor (EWS-ETS), most often the Friend leukemia integration 1 transcription factor (FLI1). Neuropeptide Y (NPY) is an EWS-FLI1 transcriptional target; it is highly expressed in ES and exerts ...
Lee Sung Ho SH Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Purpose: Recurrent syncope leads to poor functional status and psychiatric impairment in patients with syncope. The aim of the study was to prospectively analyze the risk factors attributed to syncope recurrence. Materials and Methods: Between 2009 and 2010, 289 patients with all cause of syncope visited our institution. Syncope recurrences ...
Farhangi Mahdieh Abbasalizad MA Department of Community Nutrition, School of Nutrition, Tabriz University of Medical Sciences, Tabriz, - - 2014
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver injury. Chronic exposure to oxidative stress leads to depletion of liver antioxidants and abnormal cytokine production; antioxidant therapy is one of the main therapeutic lines in NAFLD. In the current study we aimed to investigate the effect ...
Yashiro Yoshinori Y Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of - - 2014
Background:The difference between left atrial (LA) and systemic coagulation activity in paroxysmal atrial fibrillation (PAF) is unclear.Methods and Results:We enrolled 100 patients with PAF who underwent AF ablation. Warfarin was stopped 1 day before the procedure. LA volume index and LA emptying fraction were measured by 64-slice multidetector computed tomography. Immediately after ...
Sacco Rodolfo R Gastroenterology Unit, Cisanello Hospital, Pisa - - - 2014
Lactate dehydrogenase (LDH) is a predictor of clinical outcome in hepatocellular carcinoma (HCC) patients. However, its predictive role in the clinical outcomes of sorafenib treatment has been poorly documented. The correlation between LDH levels and clinical outcomes in HCC patients treated with sorafenib and included in the nationwide Italian database ...
Rudler M M AP-HP, UPMC, Department of Hepatogastroenterology, La Pitié-Salpêtrière Hospital, 47-80 boulevard de l'Hôpital, Assistance Publique-Hôpitaux de Paris, Pierre et Marie Curie University, 75013, Paris, - - 2014
All trials of severe alcoholic hepatitis (AH) have included patients with "pure" AH, i.e., without concomitant gastrointestinal bleeding (GIB). Severe AH is often suspected in cirrhotics with GIB. 1) assess the prevalence of AH in patients with GIB and Maddrey discriminant function (DF) ⩾32; 2) compare the outcome in AH ...
Kamo Kenta K Department of Orthopaedic Surgery, Yamaguchi Red Cross Hospital , Yamaguchi , - - 2014
Objectives. We clarified the prevalence of spondyloarthritis (SpA) symptom in inflammatory bowel disease (IBD). Methods. We performed the questionnaire survey of SpA symptom in IBD patients on their office visit. Results. One hundred and thirty seven patients were evaluated. The SpA features group included 46 (33.6%) patients (32 Men). Among ...
Lalosevic Jovan J Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade, - - 2014
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases that are most frequently caused by drugs. The purpose of this study was to summarize 20 years of experience with SJS and TEN in the largest dermatology clinic in Serbia. The study included 38 patients treated during the period 1993-2012. ...
Zardi Enrico Maria EM aDepartment of Clinical Medicine, 'Campus Bio-Medico' University, Rome bVI Department of Internal Medicine and Interventional Ultrasonography, Policlinico 'S. Matteo' Foundation, IRCCS, Pavia, - - 2014
Information is lacking on portal hypertensive gastropathy (PHG) in cirrhotics without varices; our aim it is to evaluate whether clinical and sonographic parameters are associated with PHG and may provide information suitable for the management of these patients. After endoscopic selection of 145 cirrhotics without varices, 75 with PHG and ...
Bogert James N JN Department of Surgery, University of Texas Medical School at Houston, Houston, TX, - - 2014
Resuscitation of the hemorrhaging patient has undergone significant changes in the last decade resulting in the concept of damage control resuscitation (DCR). Hemostatic resuscitation aims to address the physiologic derangements found in the hemorrhaging patient, namely coagulopathy, acidosis, and hypothermia. Strategies to achieve this are permissive hypotension, high ratio of ...
Porcelli Brunetta B Department of Medical Biotechnologies, Biochemistry Division, University of Siena, Siena, - - 2014
Celiac disease (CD) is an immune-mediated intolerance to dietary gluten, affecting genetically predisposed individuals. ELISA-based serological tests help to decide if further duodenal biopsy is necessary, for this the diagnostic kits have to be accurate, specific, and sensible. In this study, we investigate the performance of an ELISA that uses ...
Flanagan Eoin P EP Department of Neurology, Mayo Clinic, Rochester, - - 2014
Short transverse myelitis (STM; <3 vertebral segments) is considered noncharacteristic of neuromyelitis optica (NMO) spectrum disorders (NMOSDs). Nonappreciation of the potential for STM to occur in NMOSD may lead to increased disability from delay in diagnosis and appropriate treatment. To determine the frequency of short lesions at the initial myelitis ...
Su Jun-Feng JF Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. - - 2015
The aim of the present study was to examine clopidogrel resistance (CR) in patients with ischemic cerebral infarction and its potential association with a single nucleotide polymorphism (SNP; rs1045642) in the ABCB1 gene. Patients with ischemic cerebral infarction received clopidogrel (75 mg/day) for 7 days and were then subjected to ...
Efimova Irina I Federal State Budgetary Scientific Institution Research Institute for Cardiology, Tomsk, - - 2014
The aim of the study was to estimate regional cerebral blood flow (rCBF) and cognitive function in patients with metabolic syndrome (MetS) before and after antihypertensive combination therapy. The study included 24 patients with MetS (average age 52.4±1.6 years). All patients underwent brain single-photon emission computed tomography with technetium-99m hexamethylpropyleneamine oxime ...
Kaufman Michael M MS Center, Carolinas Medical Center, 1010 Edgehill Road North, Charlotte, NC, 28207, USA, - - 2014
The objective of this study is to characterize the timing and extent of radiologic MS disease recurrence during the 24-week natalizumab treatment interruption period in RESTORE. RESTORE was a randomized, partially placebo-controlled exploratory study. Natalizumab-treated patients with no gadolinium-enhancing (Gd+) lesions at screening (n = 175) were randomized 1:1:2 to continue natalizumab ...
Shirakabe Akihiro A Division of Intensive Care Unit, Chiba Hokusoh Hospital, Nippon Medical - - 2014
Background:Different mechanisms of acute kidney injury (AKI) may exist for acute heart failure (AHF) patients compared with other patients.Methods and Results:We analyzed data from 282 patients with AHF. The biomarkers were measured within 30 min of admission. Patients were assigned to a no-AKI (n=213) or AKI group (Class R (n=49), Class I ...
Kimbrough Dorlan J DJ Johns Hopkins University, Baltimore, MD, - - 2014
Objective: To determine whether African-American (AA) multiple sclerosis (MS) patients exhibit more retinal damage and visual impairment compared to Caucasian-American (CA) MS patients. Methods: 687 MS patients (81 AA) and 110 healthy control (HC) subjects (14 AA) were recruited at three academic hospitals between 2008 and 2012. Using mixed effects ...
Coblijn Usha K UK Department of Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands, - - 2014
One of the long-term complications of laparoscopic Roux-and-Y gastric bypass (LRYGB) is the development of marginal ulcers (MU). The aim of the present study is to assess the incidence, risk factors, symptomatology and management of patients with symptomatic MU after LRYGB surgery. A consecutive series of patients who underwent a ...
Latus J J Division of Nephrology, Department of Internal Medicine, Robert-Bosch Hospital, Auerbachstraße 110, 70376, Stuttgart, Germany, - - 2014
Nephropathia epidemica is a milder form of hemorrhagic fever with renal syndrome, caused by Puumala virus. The clinical picture is characterized by a rapid loss of renal function (acute kidney injury) and thrombocytopenia. The purpose of the current analysis was to compare the clinical course of patients presenting with or ...
Alam Md Mahboob MM Departments of Physiology and *Pediatric Rheumatology, Institute of Postgraduate Medical Education and Research, Kolkata, India. Correspondence to: Dr Md Mahboob Alam, Assistant Professor, Department of Physiology, IPGMER, 54, Alimuddin Street, Kolkata 700 016, India. - - 2014
Spirometric evaluation in juvenile systemic lupus erythematosus. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, forced expiratory flow between 25-75% of vital capacity (FEF25-75%) and peak expiratory flow rate (PEFR) of 21 patients with juvenile SLE (jSLE) were compared to controls. Reduced FVC and FEF25-75% was ...
Panegyres Peter K PK Neurodegenerative Disorders Research Pty Ltd, 4 Lawrence Avenue, 6005, West Perth, WA, Australia, - - 2014
Our aim is to elucidate the clinical variables associated with the development of manifest HD in patients with intermediate CAG repeat lengths. 2,167 participants were seen throughout 44 research sites in the United States, Canada or Australia over a five-year natural history observational study (2006-2011) (Trial # NCT00313495). The Chi-square ...
Shaban Amir A Sroke Program, Department of Neurology, Tulane University School of Medicine, New Orleans, - - 2014
A1 segment is the proximal portion of anterior cerebral artery. Absence of the A1 segment can compromise anterior cerebral collateral blood flow. Few studies have examined the association of an absent A1 segment and ischemic stroke outcome. We sought to determine the association between A1 absence and affected vessel territory, ...
Kass-Hout Tareq T Department of Neurology, Emory University School of Medicine, Atlanta, - - 2014
Reversible cerebral vasoconstriction syndrome (RCVS) is classically diagnosed based on the presence of severe thunderclap headache, focal neurologic symptoms, and the radiographic findings of reversible diffuse segmental cerebral vasoconstriction. We present a diagnostic test that may assist in the clinical diagnosis and facilitate treatment. From October 1, 2010, to August ...
Nergiz Avcioglu Sümeyra S Department of Obstetrics and Gynecology, Adnan Menderes University School of Medicine , Aydin , Turkey - - 2014
Abstract Objective: Visfatin is one of the most recent proteins shown to be highly expressed in adipose tissue. The purpose of this study was to determine visfatin levels in patients with endometrial cancer (EC). Methods: A total of 90 patients (46 EC patients and 44 healthy controls) were included in ...
Kataoka Yuko Y Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, - - 2014
Central diabetes insipidus (CDI), which is characterized by polyuria and polydipsia, is caused by a deficiency of the antidiuretic hormone arginine vasopressin (AVP). While CDI is treated with desmopressin, an analogue of AVP, the intranasal formulation is inconvenient and CDI patients reportedly prefer the oral formulation to the intranasal one. ...
Matsumoto Hideyuki H Department of Neurology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan, - - 2014
The aim of this paper is to investigate cortical excitability in patients with end-stage renal disease receiving peritoneal dialysis (PD) without any symptoms suggestive of uremic encephalopathy. We performed transcranial magnetic stimulation for 52 PD patients and 28 normal subjects. We compared the active motor threshold (AMT), resting motor threshold ...
Dushianthan Ahilanandan - - 2014
BackgroundAcute respiratory distress syndrome (ARDS) is a life-threatening critical illness, characterised by qualitative and quantitative surfactant compositional changes associated with premature airway collapse, gas-exchange abnormalities and acute hypoxic respiratory failure. The underlying mechanisms for this dysregulation in surfactant metabolisms are not fully explored. Lack of therapeutic benefits from clinical trials, ...
Notarnicola A A DIM-Rheumatology Unit, Medical School, University of Bari , - - 2014
Objectives: To assess the serum levels of interleukin (IL)-15 and IL-17 in patients with idiopathic inflammatory myopathies (IIM) and correlate them with levels of IL-1 receptor antagonist (IL-1ra), IL-6, IL-10, interferon (IFN)-γ, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1α, and MIP-1β. Possible correlations with disease activity parameters were also ...
Yuan Shanshan S Department of Endocrinology, Peking University First Hospital, Beijing 100034, - - 2014
Objective: Sera of Hashimoto's thyroiditis (HT) patients are known to exhibit elevated levels of anti-thyroglobulin IgG (TgAb IgG). Therefore, TgAb IgG represents a hallmark of this debilitating autoimmune disease. The aim of our study was to investigate the differential expression of specific glycosylation patterns of TgAb IgG from HT patients ...
Lopes Agnaldo José AJ Laboratory of Respiratory Physiology, State University of Rio de Janeiro, Brazil Rehabilitation Sciences Master's Program, Augusto Motta University Center, Rio de Janeiro, Brazil - - 2014
Bronchiectasis develops along the natural course of several respiratory and systemic conditions and induces significant changes in the morphofunctional structure of airways. Our objective was to assess the impact of various causes of bronchiectasis on clinical data, pulmonary function tests, and high-resolution computed tomography (HRCT). The present report was a ...
Camargo Cz C Rheumatology Division, Federal University of São Paulo , São Paulo , - - 2014
Objectives: To evaluate the morphological and functional abnormalities of the microcirculation associated with markers of vascular injury in patients with early systemic sclerosis (SSc). Method: Forty-six patients with early SSc were compared with 80 patients with definite SSc, 40 patients with primary Raynaud's phenomenon (PRP), and 45 healthy subjects. Widefield ...
Zhang Ning N Department of Medical Psychology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, 264 Guangzhou Road, Nanjing, 210029, - - 2014
In addition to motor symptoms, patients with Parkinson's disease (PD) may experience non-motor symptoms (NMS), more often with more advanced disease stage. However, the clinical feature of the NMS and potential risk factors that affect NMS in idiopathic PD patients remain unclear. 493 PD patients diagnosed with PD via the ...
Schievink Wouter I WI Departments of - - 2014
OBJECT Spontaneous intracranial hypotension is an increasingly recognized cause of headaches. Pituitary enlargement and brain sagging are common findings on MRI in patients with this disorder. The authors therefore investigated pituitary function in patients with spontaneous intracranial hypotension. METHODS Pituitary hormones were measured in a group of 42 consecutive patients ...
Shanmugam G Vijay GV Department of General Medicine, Pondicherry Institute of Medical Sciences , Ganapthychettikulam, Kalapet, Pondicherry , India - - 2014
Abstract There is an enormous increase in the burden of chronic kidney disease both in developing and developed countries. There is a paucity of data on obstructive sleep apnea (OSA) in chronic kidney disease (CKD) patients in India. We used a cross-sectional prospective observational study to determine the prevalence of ...
Furmaga Wieslaw W Department of Pathology, University Texas Health Science Center at San Antonio, 7704 Floyd Curl Drive, San Antonio, TX, United States. Electronic address: - - 2014
ADAMTS 13, sP-Selectin and HSP27 have been investigated as potential prognostic markers in patients with hemorrhagic shock. This study was part of a double-blind, randomized, parallel-group, controlled trial and included seventeen trauma patients presented to ED with severe hemorrhagic. The sera for testing were collected from these patients at the ...
Oliver Nora - - 2014
Abstract Acute leukemia patients develop venous thrombosis (VT) related to central venous catheters (CVC). Anticoagulation (AC) in these patients who are thrombocytopenic and often coagulopathic is challenging. To evaluate safety and efficacy of AC in treating CVC-related VT, we retrospectively compared outcomes of acute leukemia patients who were treated or ...
Probasco William W Department of Foot and Ankle Surgery, Hospital for Special Surgery, New York, - - 2014
Patients with adult-acquired flatfoot deformity (AAFD) develop peritalar subluxation, which may stem from valgus inclination of the inferior surface of the talus. We hypothesized that patients with AAFD would have an increased valgus tilt of the subtalar joint in the coronal plane compared to controls when assessed with a novel ...
Al-Maramhy Hamdi H Hamdi Al-Maramhy, Samer Sawalhi, Department of Surgery, College of Medicine, Taibah University, Al-Madina 30001, Saudi - - 2014
To assess levels of serum resistin upon hospital admission as a predictor of acute pancreatitis (AP) severity. AP is both a common and serious disease, with severe cases resulting in a high mortality rate. Several predictive inflammatory markers have been used clinically to assess severity. This prospective study collected data ...
Yu Wei-Kuang WK Department of Ophthalmology, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei, 11217, - - 2014
The aim of this study was to investigate clinical characteristics, outcome, and factors associated with response to systemic administration of steroids in patients with ocular adnexal immunoglobulin G4 (IgG4)-related disease. This was a retrospective evaluation of 11 patients with histopathologically verified ocular adnexal IgG4-related diseases at a medical center in ...
Sramko Marek M Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), Videnska 1958/9, 14021 Prague, Czech Republic. Electronic address: - - 2014
Left atrial (LA) fibrosis begets atrial fibrillation (AF). Cardiovascular magnetic resonance (CMR) using the late gadolinium enhancement (LGE) technique might visualize the LA fibrosis and thus help to choose an appropriate strategy for treatment of AF. In this regard, we investigated whether the extent of preablation LA LGE would predict ...
Hannoush H H Cardiovascular and Pulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, - - 2014
Proteus syndrome (PS) is a rare, mosaic disorder with asymmetric and distorting overgrowth of the skeletal system, skin, and adipose tissues. Cardiac abnormalities are rare in this syndrome and only two prior cases have been reported. Many patients with PS followed at our institution underwent transthoracic echocardiograms for preoperative evaluation ...
Zhong H H Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, - - 2014
Allergen-specific immunotherapy (ASIT) is the main treatment for inducing long-term immunological and clinical tolerance in patients with IgE-mediated allergic diseases. Recent open-label and controlled studies on the efficacy of ASIT in patients with atopic dermatitis (AD) have provided promising results. However, data about possible relationship between the improvement of clinical ...
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