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Results 401 - 450 of 1840
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Prasad D D Department of Nephrology, SMS Hospital, Jaipur, Rajasthan, - - 2014
We report recurrent hypokalemic periodic quadriparesis in a 30-year-old woman. Patient had also symptoms of multiple large and small joint pain, recurrent oral ulceration, photosensitivity and hair loss that were persisting since last 6 months and investigations revealed systemic lupus erythematosus (SLE) with distal tubular acidosis. Our patient was successfully ...
Yoon Byung-Nam BN Department of Neurology, Inha University Hospital, Incheon 400-711, - - 2014
Flail arm syndrome (FAS), an atypical presentation of amyotrophic lateral sclerosis (ALS), is characterized by progressive, predominantly proximal, weakness of upper limbs, without involvement of the lower limb, bulbar, or respiratory muscles. When encountering a patient who presents with this symptomatic profile, possible diagnoses include upper limb onset ALS (UL-ALS), ...
Basoglu Ozen K OK Department of Chest Diseases, Ege University Faculty of Medicine, Bornova, 35100, Izmir, Turkey, - - 2014
It is claimed that gastroesophageal reflux disease (GERD) increases in patients with obstructive sleep apnea syndrome (OSAS). We aimed to evaluate the prevalence of GERD in patients with OSAS and primary snoring and identify OSAS-related risk factors associated with GERD. In this prospective, cross-sectional, multicenter study, in total 1,104 patients ...
Yadav Ajay Kumar AK Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, 110029, India, - - 2014
Pancreatic necrosis is an important determinant of patient outcome in severe acute pancreatitis (SAP). This prospective study was conducted to evaluate if perfusion CT (PCT) can predict the development of necrosis at an early stage in SAP. PCT was performed within 72 h of abdominal pain in 57 consecutive admitted patients ...
Jaguszewski Milosz M University Heart Center, University Hospital Zurich, Raemistr. 100, 8091, Zurich, Switzerland, - - 2014
Bioresorbable vascular scaffolds (BVS) have become an emerging tool to treat coronary artery disease. However, the current use of BVS is still widely restricted to stable patients and non-complex lesions. In real-world practice patients are far more complex than those with simple type A lesions and the extended use of ...
Pezawas Thomas T Department of Cardiology, Medical University of Vienna, - - 2014
The aim of this study was to evaluate whether short-term primary preventive cardioverter-defibrillator (ICD) implantation as bridge to heart transplantation (HTX) provides any survival benefit. Thirty-three patients awaiting HTX were randomized to either conventional therapy (control group) or to primary preventive ICD implantation (ICD group). Fourteen patients had ischemic cardiomyopathy ...
Cong Chen C Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing - - 2014
Objective To explore the grey matter volume(GMV)changes in neuromyelitis optica(NMO)patients using a voxel-based morphometry method. Methods Whole brain structural images were acquired in 16 NMO patients and 16 gender-and age-matched healthy controls. Comparison of GMV between the two groups was analyzed by VBM8 toolbox of statistical parametric mapping 8. Result ...
Finkel Morgan M Division of Nephrology, Department of Pediatrics, NYU Langone Medical Center, New York, NY, - - 2014
Cisplatinum (CP) is associated with acute kidney injury. The aim of this study was to define the spectrum of CP-induced nephrotoxicity in current practice. A single-center, retrospective chart review was performed on children who received CP for treatment of a malignancy at the Hassenfeld Children's Center for Blood and Cancer ...
Yi Paul H PH Rush University Medical Center, 1611 West Harrison Street, Suite 300, Chicago, IL, 60612, - - 2014
The diagnosis of periprosthetic joint infection (PJI) in patients with failed metal-on-metal (MoM) bearings and corrosion reactions in hip arthroplasties can be particularly difficult, because the clinical presentation of adverse local tissue reactions may mimic that of PJI, because it can also occur concurrently with PJI, and because common laboratory ...
Chen Yiyi Y The First Affiliated Hospital, College of Medicine, Zhejiang University, Clinical Laboratory, Hospital Management Office, Hangzhou, China - - 2014
Acute-on-chronic hepatitis B liver failure (ACHBLF) is a serious condition with varied etiologies and manifestations, and is associated with a high mortality rate. Fibronectin is involved in a number of biological processes, including cellular adhesion, motility, differentiation, apoptosis, hemostasis, wound healing and ischemic injury. Serum fibronectin concentrations may provide prognostic ...
Chen Bu-Xing BX Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address: - - 2014
The association between blood pressure (BP) variability and stroke outcome is controversial, and there are few studies that have focused on the impact of BP variability in diabetic patients with stroke. Therefore, we aimed to examine the impact of BP variability on cardiovascular outcome in diabetic and nondiabetic patients with ...
Melles Ronald B RB Department of Ophthalmology, Redwood City Medical Center, Kaiser Permanente Northern California, Redwood City, California. Electronic address: - - 2014
To describe patterns of hydroxychloroquine retinopathy distinct from the classic parafoveal (bull's eye) maculopathy. Retrospective case series. Patients from a large multi-provider group practice and a smaller university referral practice diagnosed with hydroxychloroquine retinopathy. Patients with widespread or "end-stage" retinopathy were excluded. Review of ophthalmic studies (fundus photography, spectral-domain optical ...
Akyıldız Hızır Yakup HY Department of General Surgery, Erciyes University School of Medicine, Melikgazi, Kayseri 38039, Turkey. Electronic address: - - 2014
Acute mesenteric ischemia (AMI) is a potentially life-threatening condition because of its diagnostic difficulty, operative challenges, and comorbidities a patient may have. The aim of this study was to identify factors associated with adverse outcomes in patients with AMI. The hospital records and clinical data of all patients with AMI ...
Fukushima Masashi - - 2014
Meckel's diverticulum is a congenital anomaly of the gastrointestinal tract. About 98% of affected patients are asymptomatic. Small intestinal examination has become easier since the development of double-balloon enteroscopy. The present case series describes 10 patients with Meckel's diverticulum in whom double-balloon enteroscopy was useful for diagnosis. Ten patients (8 ...
Asciutto Giuseppe - - 2014
The presence of echolucent carotid plaques as defined by low ultrasound grey-scale median (GSM) is associated with a higher risk of stroke and myocardial infarction. Betablockers have shown possible anti-atherosclerotic effects. The aim of the present study was to determine if there is an association between carotid plaque GSM and ...
Verrotti Alberto A Department of Pediatrics, University of Perugia, Italy. Electronic address: - - 2014
Epilepsy is a frequent and severe feature of Menkes disease (MD) but only few studies described the long-term evolution of these children. We report a series of 28 epileptic MD patients, with clinical characteristics, EEG abnormalities, brain malformations and long-term outcome. EEG, clinical characteristics and neuroimaging features in 28 MD ...
Borlot Felippe F Division of Neurology, Toronto Western Hospital, Krembil Neurosciences Center, University of Toronto, Toronto, Ontario, Canada. Electronic address: - - 2014
Given verapamil's property as a glycoprotein inhibitor, this drug could increase the effective concentration of antiepileptic drugs (AEDs) in the epileptic foci, reducing the number of seizures. This pilot study was designed to evaluate the safety and efficacy of verapamil as adjunct therapy in pharmacoresistant patients with focal onset seizures. ...
Anselmo Lívia Maria Pala LM School of Medicine of Ribeirão Preto, University of São Paulo, Department of Neurology, Brazil. Electronic address: - - 2014
The objective of the present study was to assess the performance and the best indication of the polymerase chain reaction (PCR) for the detection of Toxoplasmosisgondii DNA in cerebrospinal fluid (CSF) from patients with suspected neurotoxoplasmosis. CSF samples were collected from 79 patients for amplification of the T. gondii genome ...
Verhagen M P MP Department of Cardiology, Medical Centre Alkmaar (MCA), Wilhelminalaan 12, 1815 JD, Alkmaar, the - - 2014
Since several large trials have proven the effectiveness of implantable cardioverter-defibrillators (ICDs) in patients with left ventricular dysfunction, disadvantages have become more apparent. As the prognosis of patients with cardiovascular diseases is improving, assessment of ICD patients and re-evaluation of the current guidelines is mandatory. We aimed to evaluate differences ...
Thompson Jess L JL 3rd Department of Surgery, The University of Arizona College of Medicine, Tucson, AZ, 85724-5114, - - 2014
We present a case of a patient with calcific mitral valve stenosis and plasmatic hypercoagulability. Using thrombelastography, the patient was determined to have an abnormally large velocity of plasma thrombus growth and strength with reduced vulnerability to lysis. Critically, increased carboxyhemoglobin concentration (2.4 %) was present, likely secondary to hemolysis from ...
Han Sheng S Department of Neurosurgery, The First Hospital of China Medical University, Shenyang, - - 2014
Object Allergy and immunoglobulin E levels are inversely associated with glioma risk. Previous studies have focused on respiratory and food allergies, and little information is available regarding drug allergies. This study evaluated the rate of positive penicillin skin tests (PenSTs) and blood eosinophil counts in a large population of patients ...
Teramoto Tamio T Teikyo Academic Research - - 2014
Aim: The aim of this analysis was to investigate the relationships between dyslipidemia, achieved blood pressure (BP) values and the lipid levels, as well as the control of four cardiovascular risk factors (BP, low-density lipoprotein: LDL cholesterol, hemoglobin A1c: HbA1c and smoking) and the incidence of cardiovascular disease (CVD), in ...
Nelson Winnie W WW Janssen Scientific Affairs, LLC, Raritan, NJ, - - 2014
Abstract Background-Warfarin is effective for stroke prevention in patients with atrial fibrillation (AF), but international normalized ratio (INR) levels fluctuate and frequent monitoring is necessary. Methods-This study used data from a large anticoagulation management service database to analyze the relationship between INR stabilization and warfarin utilization for >1 year in ...
Gümüşsoy Ismail I Research Assistant, Department of Dentomaxillofacial Radiology, Faculty of Dentistry,Ataturk University, Erzurum, - - 2014
Objectives: Orthodontists usually evaluate the mid-palatal sutural opening with occlusal radiography. The purpose of this paper is to evaluate the sutural opening with ultrasonography (USG) in a series of patients undergoing RPE. Methods: The study included 87 USG images and 87 occlusal radiographies from 29 healthy patients (mean age, 13.9 ...
Lóránd Veronika V University of Pécs, Faculty of Medicine, Department of Rheumatology and Immunology, 7632 Pécs, - - 2014
Musculoskeletal (MSK) involvement is a very frequent manifestation of patients with systemic sclerosis (SSc). There are several reports about clinical trials assessing musculoskeletal involvement in SSc. However, only few controlled studies have been conducted. The prevalence of musculoskeletal symptoms, clinical and radiographic findings has been assessed. The most important articular ...
Megyeri Boglarka B Department of Anaesthesiology and Intensive Care, University of Debrecen, Clinical Centre, Nagyerdei krt. 98, Debrecen H-4012, Hungary. Electronic address: - - 2014
The accuracy of CT pulmonary angiography (CTPA) in detecting or excluding pulmonary embolism has not yet been assessed in patients with high body weight (BW). This retrospective study involved CTPAs of 114 patients weighing 75-99kg and those of 123 consecutive patients weighing 100-150kg. Three independent blinded radiologists analyzed all examinations ...
Salerno Sergio S Department of Biopathology and Medical and Forensic Biotechnologies - Section of Radiological Sciences, University of Palermo; Palermo, Italy - - - 2014
Pierre Robin malformation is a rare craniofacial dysmorphism whose pathogenesis is multifactorial. Although there is some agreement in non-invasive treatment in less severe cases, the dispute is still open on cases with severe respiratory impairment. We present a semi-automatic novel diagnostic tool for calculating upper airway volume, in order to ...
Lisi Paolo P Section of Clinical, Allergological and Venereological Dermatology, Department of Medicine, University of Perugia, Perugia, - - 2014
Background: Skin toxicity is frequent and debilitating in oncologic patients treated with epidermal growth factor receptor inhibitors (EGFRIs). Grading and management of skin adverse events (AEs) are poorly standardized. Materials and Methods: We developed a new score (EGFRISTI: Epidermal Growth Factor Receptor Inhibitor-Related Skin Toxicity Index) which is able to ...
Gao Lina L Department of Neurology, Tianjin First Center Hospital of Tianjin Medical University, Tianjin, - - 2014
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder involving both upper and lower motor neurons in the cerebral cortex, brainstem and spinal cord. Vascular endothelial growth factor (VEGF) was originally described as a factor with a regulatory role in vascular growth and development, and now it also functions as ...
Erb-Eigner Katharina K Department of Radiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany. Electronic address: - - 2014
To investigate diffusion tensor abnormalities, e.g. fractional anisotropy (FA), mean diffusivity (MD), and radial diffusivity (RD), in olfactory structures of multiple sclerosis (MS) patients using diffusion tensor imaging (DTI). Institutional review board-approved prospective study on 30 MS patients and 12 healthy controls investigated with MRI including DTI. Central olfactory structures ...
Hayashida Kei - - 2014
IntroductionLittle is known about oxyhemoglobin (oxy-Hb) levels in the cerebral tissue during the development of anoxic and ischemic brain injury. We hypothesized that the estimated cerebral oxy-Hb level, a product of Hb and regional cerebral oxygen saturation (rSO2), determined at hospital arrival may reflect the level of neuroprotection in patients ...
C-F Ng Anthony - - 2014
Objective: BYSH, a herbal formula, was evaluated for efficacy and safety in a pilot study for patients with advanced hormone refractory prostate cancer (HRPC). Patients and Methods: The pilot study was designed as a single-center open-label trial. Patients with HRPC were treated with BYSH for 24 weeks. The primary end ...
Escher Felicitas F Department of Cardiology and Pneumology, CBF, Charité-Universitätsmedizin Berlin, Berlin, - - 2014
Intramyocardial inflammation is considered an adverse prognostic factor in inflammatory cardiomyopathy (CMi). However, the precise nature of immune system factors relevant for the prediction of long-term course remains elusive. The aim of this study was to analyse the prognostic relevance of perforin in a large cohort of patients with CMi. ...
Martínez-Quintana Efrén E 1Cardiology Service,Insular-Materno Infantil University HospitalLas Palmas de Gran - - 2014
Introduction: CHD patients, especially those with associated hypoxaemia, usually have some level of renal function impairment, even though they are relatively young. The aim of the study was to evaluate those clinical and analytical factors that may contribute to microalbuminuria and determine the association of 24-hour proteinuria with thrombotic events ...
Umemura Takeji T Department of Medicine, Division of Hepatology and Gastroenterology, Shinshu University School of Medicine, Matsumoto, - - 2014
Although hyponatremia is associated with a poor prognosis in liver cirrhosis, little is known about the clinical significance of serum sodium concentration in cirrhosis in Japan. This study investigated associations of mortality in Japanese cirrhosis patients taking conventional diuretics with serum sodium concentration and other clinical characteristics. A total of ...
Beumer Jan H JH Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, 15213, USA, - - 2014
Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome have often been excluded from myeloablative-conditioning regimens containing busulfan because of non-disease-related morbidity and mortality. We hypothesized that busulfan clearance (BuCL) in older patients (>60 years) would be reduced compared to that in younger patients, potentially explaining observed differences in busulfan ...
Talaat Forayssa M FM 1Department of Neurology, Faculty of Medicine, Cairo University, Cairo, - - 2014
Introduction: Epilepsy is a chronic disease that affects metabolism either alone or through the antiepileptic drug (AED) treatment. A risk of atherosclerosis has been found in epileptic patients. Aim: Prove the potential role of epilepsy and/or its treatment as atherosclerotic risk factors. Subject and Methods: Forty Egyptian patients with primary ...
Kaneko Hidehiro H Department of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, - - 2014
Functional mitral regurgitation (MR) is frequently associated with left ventricular systolic dysfunction (LVSD). Ventricular volume overload that occurs in patients with MR may lead to a progression of myocardial dysfunction. However, the prevalence and clinical outcomes of functional MR in Japanese patients with LVSD remain unclear. The aim of the ...
Sonbol M B MB Division of Hematology, Mayo Clinic, Rochester, - - 2014
Background: Mantle cell lymphoma (MCL) is a unique type of lymphoma with a prognosis intermediate between indolent and aggressive types. The purpose of this study was to study blood cytokine levels in newly diagnosed and relapsed MCL patients with respect to patterns of abnormalities and relationship to the MCL International ...
Cornelissen Liesbeth L Radiology, Department of Imaging & Pathology, University Hospitals Leuven, KU Leuven, Herestraat 49, 3000, Leuven, Belgium, - - 2014
The purpose of this study was to retrospectively assess the incidence of bowel wall oedema on computed tomography (CT) in patients with renal cell carcinoma (RCC) treated with sunitinib, and to investigate its association with diarrhoea. We conducted a retrospective analysis of all RCC patients treated with sunitinib at our ...
Zhang Xin X Xin Zhang, Shu-Zhen Wang, Jun-Fu Zheng, Wen-Min Zhao, Peng Li, Chun-Lei Fan, Bing Li, Pei-Ling Dong, Lei Li, Hui-Guo Ding, Department of Gastroenterology and Hepatology, Beijing You'an Hospital, Affiliated with Capital Medical University, Beijing 100069, - - 2014
To evaluate the efficacy and safety of tolvaptan to treat refractory ascites in decompensated liver cirrhosis patients with or without further complications, such as hepatorenal syndrome and/or hepatocellular carcinoma. Thirty-nine patients (mean age 55 years, males: 32) with decompensated liver cirrhosis and refractory ascites were enrolled. All patients received a ...
Dong Rui R Rui Dong, Zhi-Yong Guo, Jia-Rong Ding, Yang-Yang Zhou, Hao Wu, Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433, - - 2014
To compare the prevalence and diversity of gastrointestinal (GI) symptoms in patients undergoing peritoneal dialysis (PD) and hemodialysis (HD). Two hundred and ninety-four end-stage renal disease patients participated in the study, including 182 HD and 112 PD patients. Dimension scores were calculated from a modified gastrointestinal symptom rating scale (GSRS) ...
Sato K K From the Russell H. Morgan Department of Radiology and Radiological Science (K.S., K.I., K.O., S.M.), Departments of Radiology (S.H.Y.), Neurology (S.H.Y.), and Ophthalmology (S.H.Y.), and Center for Imaging Science (M.I.M.), Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Radiology (K.S.), Juntendo University School of Medicine, Tokyo, Japan; Department of Radiology (K.I.), University of Yamanashi, Yamanashi, Japan; and F.M. Kirby Research Center for Functional Brain Imaging (S.M.), Kennedy Krieger Institute, Baltimore, Maryland. - - 2014
Site-specific degeneration patterns of the infratentorial brain in relation to phylogenetic origins may relate to symptoms in patients with spinocerebellar degeneration, but the patterns are still unclear. We investigated macro- and microstructural changes of the infratentorial brain based on phylogenetic origins and their correlation with symptoms in patients with spinocerebellar ...
Gallego Lorena L Department of Oral and Maxillofacial Surgery, Cabueñes Hospital, Gijón, - - 2014
Osteonecrosis of the jaws is a clinically significant complication of bisphosphonate (BP) medications. Otherwise, the effects of BPs on oral soft tissue or cells remain unknown. The main objective of the present study was to determine whether the presence of sinus mucosal thickening was significantly related to BP-related osteonecrosis of ...
Enders Philip P Department of Ophthalmology, University Hospital of Cologne, Cologne, - - 2014
To analyze long-term changes of systemic vascular endothelial growth factor (VEGF) levels in patients treated with ranibizumab for neovascular age-related macular degeneration. Sixty-one patients with neovascular age-related macular degeneration and 68 age-matched controls were included in the study. Patients were treated with ranibizumab on a pro re nata regimen. Plasma ...
Konarzewski Marcin M Department of Cardiology, Wincent a Paulo Hospital in Gdynia, Gdansk, - - 2014
Background: A high level of circulating PCSK9 binds to the LDL receptor, reduces its cell's surface density and leads to hypercholesterolemia. The aim of this study was to examine the circulating PCSK9 level in patients with kidney disease. Methods: Out of the patients treated in our Departments we selected: (a) ...
Zeng Yue Y Department of Gastroenterology (YZ, YL, CH, XW), Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China; Department of Gastroenterology (WZ), Shanghai Huadong Hospital, Fudan University, Shanghai, - - 2014
Hypertriglyceridemia (HTG) is a well-recognized cause of acute pancreatitis (AP). However, the role of HTG in modulating disease course remains to be cleared. We aimed to explore the impact of HTG on the outcome of acute biliary pancreatitis (ABP). A total of 90 ABP patients with HTG were enrolled in ...
De Silva Shamila T ST aUniversity Medical Unit, Colombo North Teaching Hospital Departments of bMedicine cPublic Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri - - 2014
Diagnostic criteria of hepatorenal syndrome type 2 (HRS2) fail to detect milder degrees of chronic renal dysfunction (CRD) in cirrhosis and exclude patients with pre-existing kidney disease. Definitions addressing this have been proposed by Working Party of the Acute Dialysis Quality Initiative and International Ascites Club (ADQI-IAC). We studied the ...
Xu Bei B Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, - - 2014
Anti-viral therapy is important in advanced liver fibrosis/cirrhosis with chronic hepatitis B (AdLF-CHB) patients, but complete regression of cirrhosis remains to be challenge. We aimed to investigate whether up to 10 years lamivudine treatment achieves liver fibrosis/cirrhosis regression in AdLF-CHB patients. It is evaluated improvement of hepatic fibrosis/cirrhosis, virological response ...
Messenger Wyatt W Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, - - 2014
To characterise uveitis in association with multiple sclerosis (MS). We conducted a retrospective chart review of patients with uveitis and MS at two uveitis centres (Portland, Oregon, USA and Heidelberg, Germany). Baseline characteristics and ophthalmic data were collected at the patient's first and last visits. Additionally, neurological records were obtained ...
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