Search Results
Results 351 - 400 of 1220
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Carrera Emmanuel - - 2009
Transcranial Doppler (TCD) is widely used to monitor the temporal course of vasospasm after subarachnoid hemorrhage (SAH), but its ability to predict clinical deterioration or infarction from delayed cerebral ischemia (DCI) remains controversial. We sought to determine the prognostic utility of serial TCD examination after SAH. We analyzed 1877 TCD ...
Zheng L Z - - 2009
BACKGROUND AND PURPOSE: Because of the relatively rare and extremely varied clinical presentations, arteriovenous malformations (AVMs) involving the auriculae are technically challenging clinical entities to diagnose and, ultimately, manage. The purpose of our study was to present our initial experience of ethanol embolization in a series of 17 patients with ...
Ferro José M - - 2009
BACKGROUND AND PURPOSE: Diagnostic delay of cerebral vein and dural sinus thrombosis may have an impact on outcome. METHODS: In the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) cohort (624 patients with cerebral vein and dural sinus thrombosis), we analyzed the predictors and the impact on outcome ...
Vergouwen Mervyn D I - - 2009
The pathogenesis of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) remains unknown. Besides vasospasm, microthrombosis might have an important function. As in patients with thrombotic thrombocytopenic purpura an A Disintegrin And Metalloprotease with ThromboSpondin repeats-13 (ADAMTS13) deficiency leads to higher concentrations of large von Willebrand factor (vWF) multimers ...
Incecik Faruk - - 2009
BACKGROUND: Reversible posterior leukoencephalopathy syndrome (PRES) is a neurological disorder characterized by signs of posterior cerebral edema upon radiographic examination. MATERIALS AND METHODS: We retrospectively analyzed the records of nine children with the diagnosis of PRES. RESULTS: Of the nine patients, seven were receiving immunosuppressive therapy and two were acute ...
Thompson Andrew L - - 2009
PURPOSE: The computed tomogram angiography (CTA) 'spot sign' describes foci of intralesional enhancement associated with hematoma expansion in primary intracerebral hemorrhage patients. A consistent radiological definition is required for two proposed recombinant Factor VIIa trials planning patient dichotomization according to 'spot sign' presence or absence. We propose radiological criteria for ...
Giuliodori G - - 2009
BACKGROUND AND PURPOSES: Neurological involvement in systemic sclerosis is unusual despite the possible cerebral localization of vascular lesions. The aim of this study was to evaluate cognitive performances and cerebral vasoreactivity in young scleroderma patients without any signs or symptoms of nervous system involvement. METHODS: Sixteen scleroderma patients and 16 ...
Ocon Anthony J - - 2009
Postural tachycardia syndrome (POTS), a chronic form of orthostatic intolerance, has signs and symptoms of lightheadedness, loss of vision, headache, fatigue, and neurocognitive deficits consistent with reductions in cerebrovascular perfusion. We hypothesized that young, normocapnic POTS patients exhibit abnormal cerebral autoregulation (CA) that results in decreased static and dynamic cerebral ...
Czabanka Marcus - - 2009
We analyzed cortical microvascular parameters using intraoperative ICG (Indocyaninegreen)-Videoangiography in 13 patients with Moyamoya disease, and carried out correlative studies by comparing them with clinical parameters obtained by digital subtraction angiography, physical examination, and regional cerebral blood flow studies. Patients with reduced cerebrovascular reserve capacity were characterized by increased microvascular ...
Raymond-Martimbeau Pauline - - 2009
OBJECTIVES: To prospectively study the association between patent foramen ovale (PFO) detected by contrast transcranial Doppler (cTCD) and adverse events (AEs) reported by patients after ultrasound-guided foam sclerotherapy (UGFS) for the treatment of varicose veins. METHODS: All patients reporting AEs after UGFS were studied using cTCD directed at the middle ...
Santos Marcio Luiz Tostes dos - - 2009
The purpose of this study was to correlate the angioarchitecture of brain arteriovenous malformations (AVM) with their clinical presentation. A total of 170 patients with AVM 78 males and 92 females, were studied. Univariate and multivariate analyses were conducted in order to test the associations between morphological features and clinical ...
Lo Bruce M - - 2009
Headache is a common presenting complaint in the emergency department (ED) that sometimes requires a diagnostic workup including a lumbar puncture (LP). An LP is often used to evaluate patients in the ED for an acute neurologic process. Xanthochromia seen on cerebrospinal fluid from an LP is often considered to ...
Hopf N J - - 2009
INTRODUCTION: Surgical management of multiple intracranial aneurysms may be difficult if located bilaterally. In the case of bilateral middle cerebral artery (MCA) aneurysms, surgical treatment through a unilateral approach is generally not recommended. In this study we describe the surgical technique and important factors that enable treatment of bilateral MCA ...
L?szl? Aranka - - 2009
The aim of our study was to determine regional cerebral blood flow (rCBF) abnormalities in different types of enzymopathies. PATIENTS AND METHODS: Among the patients with genetically determined enzymopathies 3 patients had aminoacidopathies, and 11 had different types of encephalopathies, from which 10 had mitochondrial encephalomyopathy (MEMP), and 1 patient ...
Lv Xianli - - 2010
Isolated oculomotor nerve palsy (IOP) can be annoying for a patient and can also be the only clue to a potentially devastating and life-threatening disease. In order to understand its clinical spectrum and management better we analyzed the files of 13 patients seen at our institution over a 3-year period. ...
Mohler Emile R ER - - 2009
PURPOSE: We describe a novel approach for detecting vascular abnormalities deep in the digits by means of a handheld illuminator. METHODS: Ten patients with hereditary hemorrhagic telangiectasia were compared with 10 controls for telangiectases in the fingers using a handheld otoscope. RESULTS: This noninvasive transillumination method revealed telangiectases in 9 ...
Mascio Christopher E - - 2009
In view of the existing controversy concerning the best perfusion technique during deep hypothermic circulatory arrest (DHCA) for neonatal heart operations, we examined intraoperative rSO2 to help define an optimal interval for an intermittent antegrade cerebral perfusion (IACP) strategy. Records of patients undergoing stage 1 palliation (S1P) and repair of ...
Fallon Brian A - - 2009
There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease. To determine whether patients with a history of well-characterized Lyme disease and persistent cognitive deficit show abnormalities in global or topographic distributions of regional cerebral blood flow (rCBF) or cerebral metabolic rate (rCMR). Case-controlled ...
Sriskandan Neshe - - 2010
Hypersalivation associated with cerebral palsy may be treated with injection of botulinum toxin A (BTX-A) into the submandibular gland, and the use of ultrasound permits its accurate administration. In our series four patients with cerebral palsy and hypersalivation had bilateral ultrasound-guided injection of BTX-A into the submandibular gland. At 4 ...
Kang Dong-Hun - - 2009
We reviewed and compared the clinical course and long-term prognosis of patients with non-aneurysmal subarachnoid hemorrhage (SAH) with and without a perimesencephalic pattern of hemorrhage on CT scan. In 876 patients with spontaneous SAH, 52 (5.9%) were diagnosed with non-aneurysmal SAH. Based on their CT scans, the SAH was classified ...
Pauls Ryan J - - 2009
PURPOSE: Deep anesthesia during microvascular decompression (MVD) for trigeminal neuralgia and cerebral aneurysm clipping may delay emergence. A new electroencephalographic (EEG) monitor, the EEGo, processes a raw EEG signal using time-delay analysis to display a reproducible signal transition from deep anesthesia through the excitement state to the awake state. We ...
Delgado Almandoz J E - - 2009
BACKGROUND AND PURPOSE: Multidetector CT angiography (MDCTA) is emerging as the favored initial diagnostic examination in the evaluation of patients presenting with spontaneous intraparenchymal hemorrhage (IPH). This study aims to evaluate the diagnostic accuracy and yield of MDCTA for the detection of vascular etiologies in adult patients presenting to the ...
Bahou Yacoub G - - 2009
To study intracerebral hemorrhage (ICH) at Jordan University Hospital (JUH) with the aim of assessing prevalence, age/gender distribution, causes, clinical manifestations, and location of ICH on CT brain, treatment modalities and outcome, and to compare these findings with those from Middle Eastern and Western literature. Among 1498 patients with stroke ...
Sherlock M - - 2009
BACKGROUND: Hyponatraemia is a well-recognised complication of neurosurgical conditions, but the incidence and implications have not been well documented. OBJECTIVE: To define the incidence, pathophysiology and clinical implications of significant hyponatraemia in several neurosurgical conditions. METHODS: All patients admitted to the Irish National Neurosciences Centre at Beaumont Hospital, Dublin with ...
Agostoni Elio - - 2009
Cerebral venous thrombosis (CVT) was formerly considered a rare disorder, associated with an unfavorable outcome. More recent data based on modern imaging techniques, however, have changed our perception of this disorder. The use of angiography and, especially, MRI have allowed an early diagnosis and have proved that the incidence of ...
Jeffree R L - - 2009
We present a retrospective, case-controlled study of the degree of over-warfarinisation and the frequency of International Normalized Ratio (INR) monitoring in patients with spontaneous intracranial haemorrhage (ICH) compared with a control group without ICH. A higher proportion of patients with ICH were taking warfarin than patients in the control group ...
Samuelsson Carolina - - 2009
BACKGROUND: This observational microdialysis (MD) study of 33 subarachnoid hemorrhage patients explores brain interstitial levels of glutamine, glutamate, lactate and pyruvate, and their relationship to clinical status and clinical course at the neurointensive care unit. METHODS: The focus was on ischemic events, defined by clinical criteria or by radiology, and ...
Leung Yvette - - 2009
We previously reported that IBD patients who are non-responders to thiopurines with preferential shunting of metabolites to hepatotoxic 6-methylmercaptopurine ribonucleotides compared to 6-thioguanine nucleotides can reverse the ratio of 6-MMP/6-TGN and respond to thiopurines with the addition of allopurinol. The objective of this study is to report long term efficacy ...
Geibprasert Sasikhan - - 2009
OBJECT: The goal in this study was to present possible pathological mechanisms, clinical and imaging findings, and to describe the management and outcome in patients with hydrocephalus due to unruptured pial brain arteriovenous malformations (AVMs). METHODS: Medical records and imaging findings in 8 consecutive patients with hydrocephalus caused by AVMs ...
Yeung Robert - - 2009
BACKGROUND AND PURPOSE: To compare the efficacy of computed tomographic angiography (CTA) to that of digital subtraction angiography (DSA) in the detection of secondary causes of intracerebral hemorrhage (ICH). METHODS: Between January 2001 and February 2007 there were 286 patients that had both CTA and DSA for intracranial hemorrhage of ...
Nishikawa Tomofumi - - 2009
BACKGROUND: In patients suffering from intracerebral hemorrhage (ICH) with ventricular hemorrhage (IVH), the IVH severity is thought to be associated with prognosis. Therefore, treating IVH may be a beneficial therapeutic target. In this study, by examining the associations among IVH severity, hydrocephalus, initial level of consciousness and prognosis, we attempted ...
Harboe E - - 2009
BACKGROUND AND PURPOSE: It is frequently thought that cerebral white matter hyperintensities (WMHs) on T-2 weighted MRI scans are increased in patients with autoimmune diseases. An increased frequency of WHMs has been described in primary Sjögren's syndrome (PSS), but no controlled studies exist. The aim of this study was therefore ...
Stamelou Maria - - 2009
Indirect evidence from laboratory studies suggests that mitochondrial energy metabolism is impaired in progressive supranuclear palsy (PSP), but brain energy metabolism has not yet been studied directly in vivo in a comprehensive manner in patients. We have used combined phosphorus and proton magnetic resonance spectroscopy to measure adenosine-triphosphate (ATP), adenosine-diphosphate ...
Nogui Fábio Luís Nascimento - - 2009
Encephalitis caused by Toxoplasma gondii is the most common cause of central nervous system damage in patients with acquired immunodeficiency syndrome (AIDS). Toxoplasma may infect any of the brain cells, thus leading to non-specific neurotoxoplasmosis clinical manifestations including focused or non-focused signs and symptoms of central nervous system malfunction. Clinical ...
Romero Javier M - - 2009
The objective of this study is to measure the accuracy of multidetector CT angiography (MD CTA) in the detection of vascular abnormalities in patients <or=40 years with spontaneous intraparenchymal hemorrhage (IPH) presenting to the emergency department. After institutional review board approval, a retrospective study was performed of 43 consecutive patients ...
Seule Martin A - - 2009
OBJECTIVE: To evaluate the feasibility and safety of mild hypothermia treatment in patients with aneurysmal subarachnoid hemorrhage (SAH) who are experiencing intracranial hypertension and/or cerebral vasospasm (CVS). METHODS: Of 441 consecutive patients with SAH, 100 developed elevated intracranial pressure and/or symptomatic CVS refractory to conventional treatment. Hypothermia (33-34 degrees C) ...
Roth C - - 2009
BACKGROUND: Clinical and imaging abnormalities similar to those seen in posterior reversible encephalopathy syndrome (PRES) have been observed in patients with eclampsia. It remains unclear whether both conditions are in fact the same disease entity. METHODS: We retrospectively identified 21 patients with PRES and separated them into 2 groups: patients ...
Jang Sung Ho - - 2009
Diffusion tensor image tractography (DTT) can visualize white matter tracts and provide a powerful vehicle with which to investigate the neural pathway at the subcortical level. We attempted to demonstrate the clinical significance of transcallosal fibers (TCF) originating from the corticospinal tract in patients with corona radiata infarct located below ...
Huang Abel Po-Hao - - 2009
OBJECTIVE: It has been noted that the posterior circulation serves as an important source of collateral blood supply in moyamoya disease. Since most of the literature has focused on non-operative cases and many symptomatic patients receive surgical revascularization, we evaluated the posterior circulation changes after revascularization and found that progressive ...
Jain Vidhan - - 2009
BACKGROUND: Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine implicated in the pathogenesis of a number of human diseases including inflammatory neurological diseases. Its role in the pathogenesis of cerebral malaria is unknown. Cerebral malaria is a life-threatening complication of falciparum malaria with approximately 20%-30% of patients dying despite ...
Ronne-Engström Elisabeth - - 2009
In this study we present the population-based patient material with spontaneous SAH, treated in our Neurosurgical unit during the 10 years (1997-2006) after the introduction of endovascular treatment of aneurysms (EVT) in our hospital. All patients that had a spontaneous SAH and a potential to survive were admitted. The present ...
Carvi y Nievas Mario Nazareno - - 2009
BACKGROUND: To analyze the management and outcome of patients presenting with atypical causes of intracranial subarachnoid hemorrhage (SAH). METHODS: We performed a review of our last 820 nontraumatic-SAH patients and analyzed the management and outcome of patients where the SAH origin was not a ruptured aneurysm. The Glasgow Outcome Scale ...
Mascarenhas Lino - - 2009
A hypo-coagulated 58-year-old female complained of headaches right after being exposed to the first pressure waves generated during an exhibition of fireworks. The day after she presented with seizures and the CT scan showed subdural hemorrhage over the left frontoparietal sulci. Eight hours after admission she disclosed left lower limb ...
Fontaine Eustace J - - 2008
The objective of this study was to determine the brain volume changes that occur secondary to hemofiltration during cardiopulmonary bypass in patients with renal failure. We hypothesized that in patients with elevated urea levels, quick aggressive hemofiltration could be associated with cerebral edema. We constructed a simple two-compartment model similar ...
Kalita J - - 2009
OBJECTIVES: To study the types, frequency and clinical correlates of brain herniations in patients with intracerebral hemorrhage (ICH). METHODS: In 24 patients with ICH (putaminal 22 and thalamic 2) features of raised intracranial pressure (ICP), such as hyperventilation, extensor rigidity, pupillary asymmetry and pyramidal signs on the non-hemiplegic side, were ...
Klein M - - 2008
Besides being a treatment option for narcolepsy, gamma-hydroxybutyrate is used as an adjuvant during anesthesia in Europe. In addition, it is illegally used as a recreational drug. Fixed and dilated, asymmetric pupils developed in 2 patients during continuous therapy with intravenous gamma-hydroxybutyrate, which was added to the long-term anesthetics fentanyl ...
Yoon Seok-Mann - - 2008
The serum S100 protein has been known to reflect the severity of neuronal damage. The purpose of this study was to assess the prognostic value of the serum S100 protein by Elecsys S100 immunoassay in patients with subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) and to establish reference value for ...
Hervé Dominique - - 2009
Three-dimensional MRI segmentation may be useful to better understand the physiopathology of lacunar infarctions. Using this technique, the distribution of lacunar infarctions volumes has been recently reported in patients with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Whether the volume of each lacune (individual lacunar volume [ILV]) is ...
Aralasmak Ayse - - 2009
INTRODUCTION: We retrospectively evaluated computed tomography angiography (CTA) and perfusion imaging (CTP) of patients with aneurysmal subarachnoid hemorrhage (SAH) for any correlation between degree of vasospasm and perfusion deficit. MATERIALS AND METHODS: Sequentially performed CTP and CTA of 41 patients at least at the third day of postbleeding were reviewed ...
Flaherty M L - - 2008
Among patients with intracerebral hemorrhage (ICH), warfarin use before onset leads to greater mortality. In a retrospective study, we sought to determine whether warfarin use is associated with larger initial hematoma volume, one determinant of mortality after ICH. We identified all patients hospitalized with ICH in the Greater Cincinnati region ...
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