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Results 351 - 400 of 1608
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Breithardt Günter G Department of Cardiovascular Medicine, Division of Electrophysiology, University Hospital Münster, Von-Esmarch-Strasse 117, Münster D-48149, Germany - - 2014
We investigated clinical characteristics and outcomes of patients with significant valvular disease (SVD) in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial. ROCKET AF excluded patients with mitral stenosis or artificial ...
Estes Jaclyn L JL *Weill Cornell Medical College and †Department of Radiology, Weill Cornell Medical College, Cornell University; ‡NewYork-Presbyterian Hospital; §Department of Public Health and ‖Department of Ophthalmology, Weill Cornell Medical College, Cornell University, New York, New York, - - 2014
The purpose of this study was to determine if a significant difference exists in the nasolacrimal duct volume of subjects with primary nasolacrimal duct obstruction compared with that of controls. This was a retrospective, case-control study of 70 subjects with prior maxillofacial CT scans, including 35 subjects with obstruction and ...
Do Bao Anh BA Faculty of Medicine, McGill University, Montreal, Quebec, Canada - - 2014
Many predictive models for risk of malignancy in well-differentiated thyroid cancer (WDTC) have been proposed, and many scoring systems for thyroid cancer prognosis have been established. Age is taken in consideration in all. Our main goal is to establish whether patients' age has a correlation with the rate of malignancy, ...
Djordjevic-Jocic Jasmina J Clinic of Ophthalmology, Faculty of Medicine, University of Nis, Nis, - - 2014
The goal of this study was to examine, the relationship between chronic kidney disease (CKD) and glaucomatous optic disc neuropathy in a cohort of patients from the south-east Serbia and to determine whether limited screening for glaucoma in specific subgroups of patients with CKD is reasonable and justifiable. This cross-sectional ...
Wang Joanna Y JY Division of Pediatric Neurosurgery, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; - - 2014
Object The most common neurosurgical condition observed in preterm infants is intraventricular hemorrhage (IVH), which often results in posthemorrhagic hydrocephalus (PHH). These conditions portend an unfavorable prognosis; therefore, the potential for poor neurodevelopmental outcomes necessitates a better understanding of the comparative effectiveness of 2 temporary devices commonly used before the ...
Guo Wenbin W Mental Health Institute of the Second Xiangya Hospital, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan 410011, China; Mental Health Center, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, - - 2014
Studies have shown that patients with schizophrenia and their siblings share decreased gray matter (GM) volumes in certain brain regions, which may represent candidate endophenotypes of schizophrenia. However, the specificity and utility of these possible endophenotypes in relation to schizophrenia remain unclear. Twenty drug-naive, first-episode schizophrenia patients and 20 first-degree ...
Di Lernia V V Dermatology Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, - - 2014
Psoriasis is a highly heritable disease. It has been suggested that psoriasis is preferentially transmitted from fathers. To evaluate the degree of familial aggregation of psoriasis; to determine the recurrence risk ratio (λR ) of psoriasis in first, second and third degree relatives of patients with psoriasis; and to investigate ...
Yoon Jung Han JH Department of Neurology, Ajou University School of Medicine, Suwon, South - - 2014
Levodopa (l-dopa) therapy in Parkinson's disease (PD) increases serum homocysteine levels because of its metabolism via catechol O-methyltransferase, which may lead to endothelial dysfunction. We enrolled 40 PD patients treated with l-dopa, 33 PD patients treated with l-dopa/entacapone, 22 untreated PD and 30 controls, and compared the flow-mediated dilation in ...
Sliwińska-Mossoń Mariola M Department of biomedical and environmental analysis, Wrocław Medical University, 211 Borowska, Poland. Electronic address: - - 2014
The aim of the study was to provide knowledge on somatostatin and its action on the body, particularly the pancreas - in physiological and pathological conditions. In order to get to know the properties of somatostatin, a hormone discovered over forty years ago, many studies that define its structure and the mechanisms ...
Chen Ji-Yih JY Attending physician. Department of Medicine, Division of Allergy, Immunology and Rheumatology, Chang Gung Memorial Hospital, Chang Gung University College of - - 2014
Objective: To determine whether copy number variations (CNVs) of FCGR3A and FCGR3B genes are associated with SLE and RA in Taiwanese. Methods: CNV genotypes of FCGR3A and FCGR3B were determined in 846 SLE patients, 948 RA patients, and 1420 healthy controls with custom TaqMan CNV assays. Genotypes of FCGR3A and ...
Letanneux Alban A Aix-Marseille Université, CNRS, Laboratoire Parole et Langage, UMR 7309, Aix-en-Provence, - - 2014
Micrographia, an abnormal reduction in writing size, is a specific behavioral deficit associated with Parkinson's disease (PD). In recent years, the availability of graphic tablets has made it possible to study micrographia in unprecedented detail. Consequently, a growing number of studies show that PD patients also exhibit impaired handwriting kinematics. ...
Du T T Department of General Surgery, Zhongnan Hospital, School of Medicine, National Wuhan University, Wuhan, Hubei Province, - - 2014
Deep venous thrombosis (DVT) is a common surgical complication in cancer patients and evidence that inflammation plays a role in the occurrence of DVT is increasing. We studied a population of cancer patients with abdominal malignancies with the aim of investigating whether the levels of circulating inflammatory cytokines were associated ...
Moe Maung Maung Myat MM Oncology Department, Singleton Hospital, Swansea, - - 2014
Background: We wanted to evaluate the impact of peritoneal dialysis on trabectedin therapy in terms of side effects, response and levels in the blood and dialysate of a patient on peritoneal dialysis for end-stage renal failure caused by previous ifosfamide therapy. This has not yet been reported in the medical ...
Kim Kyoung-Eun KE Department of Rehabilitation Medicine, Armed Forces Capital Hospital, 81, Saemaeul-ro 177beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do Zip code: 463-040, Republic of Korea. Electronic address: - - 2014
A brachial plexus lesion is not common in hereditary neuropathy with liability to pressure palsy (HNPP). We report the clinical and electrodiagnostic features of young soldiers with HNPP presenting with brachial plexopathy. By reviewing 2year medical records from Korean military hospitals, we identified soldiers with brachial plexus lesions. Among them, ...
Navaravong Leenhapong L Comprehensive Arrhythmia Research and Management (CARMA) Center, University of Utah Division of Cardiovascular Medicine, Salt Lake City, - - 2014
Chronic kidney disease (CKD) and atrial fibrillation (AF) often co-exist. We studied the association of CKD with atrial fibrosis and the effect of AF ablation on kidney function. AF Patients who had a pre- and post-ablation serum creatinine and who completed a late gadolinium enhancement cardiac MRI (LGE-MRI) prior to ...
Bregnbak David D Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Hospital Gentofte, Ledreborg Allé 40, Gentofte, 2820, - - 2014
Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states. To characterize patients with chromium allergy and their disease, to serve as a baseline ...
Poulsen Frantz R FR Department of Neurosurgery, Odense University Hospital, Odense, - - 2014
Mortality and morbidity have remained high in bacterial meningitis. Impairment of cerebral energy metabolism probably contributes to unfavorable outcome. Intracerebral microdialysis is routinely used to monitor cerebral energy metabolism, and recent experimental studies indicate that this technique may separate ischemia and non-ischemic mitochondrial dysfunction. The present study is a retrospective ...
Vallejo A A Department of Infectious Diseases, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University Hospital Ramón y Cajal, Ctra Colmenar Km 9, 28034, Madrid, Spain, - - 2014
Visceral leishmaniasis (VL) in HIV-1-infected patients has been associated with poor immunological recovery and frequent disease relapses. The aim of this study was to analyse the role of T cell populations, Treg cells and CCR5 density in patients with VL compared to HIV-1-infected patients without leishmaniasis. A cross-sectional study of ...
Solazzo Antonio A Department of Radiology, Second University of Naples, Piazza Miraglia 2, 80138, Naples, Italy, - - 2014
The aim of this study was to find whether there are manometric pharyngeal changes that may have diagnostic and prognostic relevance in the amyotrophic lateral sclerosis (ALS) patient who does not show changes in contrast-medium oropharyngeal transit in a videofluoroscopic swallowing study. Ten ALS patients, with an ALS Severity Scale ...
Shin Takeshi T Department of Urology, Dokkyo Medical University Koshigaya Hospital , Koshigaya , - - 2014
Abstract This study aimed to examine the effect of mesalazine on fertility. In this retrospective analysis of 1,225 male subfertile patients, we reviewed the cases of inflammatory bowel disease (IBD) in the medical records and evaluated the prevalence of the disease in our reproduction center. Specifically, we examined IBD patients ...
Fehring Thomas K TK OrthoCarolina Hip and Knee Center, 2001 Vail Avenue, Suite 200A, Charlotte, NC, 28209, USA, - - 2014
To determine the importance of MRI abnormalities in metal-on-metal (MoM) bearings, it is important to understand the baseline features of this diagnostic tool in conventional metal-on-polyethylene (MoP) bearings. What are the frequency, size, and types of MRI-documented adverse local tissue reactions in asymptomatic patients with MoP bearings? We recruited 50 ...
Fadini Gian Paolo GP University of Padova, Department of Medicine, Division of Metabolic - - 2014
Context. Acromegaly increases cardiovascular risk, possibly due to the high prevalence of classical risk factors. However, in vitro studies show a protective role of GH/IGF-1 on the endothelium. Objective. To investigate circulating endothelial progenitor cells (EPCs), a marker of vascular regeneration, in acromegalic patients and how they are affected by ...
Ling Chen C Department of Nephrology, Beijing Children's Hospital affiliated to Capital Medical University, West District Nan Li Shi Lu 56th, Beijing, 100045, - - 2014
Early diagnosis of minimal change disease (MCD) in nephrotic syndrome (NS) patients remains challenging. Doctors often make a diagnosis of MCD using invasive renal biopsy. CD80, a transmembrane protein, is present on podocytes in a number of experimental models of NS. Urinary CD80 levels are significantly elevated in MCD but ...
Domenis Danielle Ramos DR Federal University of Sergipe , Lagarto , - - 2014
Purpose: A common presentation of mitochondrial myopathies is chronic progressive external ophthalmoplegia (CPEO). Dysphagia is a complaint in about 50% of cases. Methods: This investigation evaluated pharyngeal transit in patients with CPEO. Videofluoroscopic swallowing evaluation was performed with paste, liquid and solid boluses in 14 patients with CPEO and in ...
Xiang Li L Li Xiang, Qiang Zhan, Xin-Hua Zhao, Ya-Dong Wang, Yang-Zhi Xu, Ai-Min Li, Wei Gong, Yang Bai, Fa-Chao Zhi, Si-De Liu, Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510000, Guangdong Province, - - 2014
To determine the miss rate for colorectal flat adenomas during colonoscopy and the risk factors. Flat adenomas are frequently missed during colonoscopy. However, the risk factors that influence their miss rates are unclear. This was a multicenter, retrospective study in which patients diagnosed with colorectal adenomas at a diagnostic colonoscopy ...
Wu Wen-Guang WG Wen-Guang Wu, Wen-Jie Zhang, Jun Gu, Ming-Ning Zhao, Ming Zhuang, Ying-Bin Liu, Xue-Feng Wang, Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai 200092, - - 2014
To describe an optimal route to the Braun anastomosis including the use of retrieval-balloon-assisted enterography. Patients who received a Billroth II gastroenterostomy (n = 109) and a Billroth II gastroenterostomy with Braun anastomosis (n = 20) between January 2009 and May 2013 were analyzed in this study. Endoscopic retrograde cholangiopancreatography ...
Trad Sélim S AP-HP, Internal Medicine department 2, Groupe Hospitalier Pitié Salpêtrière, 75013 Paris, France. Electronic address: - - 2014
The purpose of this study was to estimate the prevalence of monoclonal immunoglobulin (MIg) among patients with systemic sclerosis (SSc) according to method of detection (capillary electrophoresis or immunofixation) and to search for any related clinical correlations. Retrospective multicenter comparison of capillary electrophoresis and immunofixation results in SSc patients and ...
Ferreira Daniel D Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, - - 2014
New therapies with disease-modifying effects are urgently needed for treating Alzheimer's disease (AD). Nerve growth factor (NGF) protein has demonstrated regenerative and neuroprotective effects on basal forebrain cholinergic neurons in animal studies. In addition, AD patients treated with NGF have previously shown improved cognition, EEG activity, nicotinic binding, and glucose ...
Gallego-Jutglà Esteve E Data and Signal Processing Group, University of Vic - Central University of Catalonia, Vic, Catalonia, - - 2014
Despite recent advances, early diagnosis of Alzheimer's disease (AD) from electroencephalography (EEG) remains a difficult task. In this paper, we offer an added measure through which such early diagnoses can potentially be improved. One feature that has been used for discriminative classification is changes in EEG synchrony. So far, only ...
Cheung Eva W EW Department of Pediatrics, Division of Critical Care Medicine, Columbia University, New York, New York. Electronic address: - - 2014
We investigated the influence of coronary artery abnormalities on outcome in patients with pulmonary atresia/intact ventricular septum (PA-IVS) for planned single-ventricle palliation. Catheterization and medical records were reviewed in patients with PA-IVS for planned single-ventricle palliation at our institution between 2000 and 2012. Primary outcome was death or transplantation. Patients ...
Testani Jeffrey M JM Department of Internal Medicine and Program of Applied Translational Research, Yale University School of Medicine, New Haven, Connecticut. Electronic address: - - 2014
Differentiating heart failure (HF) induced renal dysfunction (RD) from intrinsic kidney disease is challenging. It has been demonstrated that biomarkers such as B-type natriuretic peptide (BNP) or the blood urea nitrogen to creatinine ratio (BUN/Creat) can identify high vs. low risk RD. Our objective was to determine if combination these ...
Barbarroja-Escudero José J Department of Medicine, Universidad de Alcalá, Alcalá de Henares, - - 2014
Background: T lymphocytes are involved in the pathogenesis of nonallergic asthma. The objective of this study was to characterize the subset distribution and pattern of chemokine receptor expression in circulating T lymphocyte subsets from nonallergic asthma patients. Methods: Forty stable nonallergic asthma patients and 16 sex- and age-matched healthy donors ...
Song Sang Hoon SH Clinical Proteomics Laboratory, Seoul National University Hospital, Seoul, Korea. ; Biomedical Research Institute and Department of Laboratory Medicine, Seoul National University Hospital, Seoul, - - 2014
Effective treatment and monitoring of tuberculosis (TB) requires biomarkers that can be easily evaluated in blood samples. The aim of this study was to analyze the serum proteome of patients with TB and to identify protein biomarkers for TB. Serum samples from 26 TB patients and 31 controls were analyzed ...
Ofte Hilde K HK Nordland Hospital Trust, Norway - - 2014
Cluster headache (CH) attacks are accompanied by cranial autonomic symptoms indicative of parasympathetic hyperactivity and sympathetic dysfunction ipsilateral to the pain. We aimed to assess cranial autonomic function in CH patients during the remission phase of cluster headache. During a remission phase, 38 episodic CH patients underwent the following: dynamic ...
Kooiman J J Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the - - 2014
Hydration to prevent contrast induced-acute kidney injury (CI-AKI) induces a diagnostic delay when performing CT-pulmonary angiography (CTPA) in patients suspected of acute pulmonary embolism (PE). To analyze whether withholding hydration is non-inferior to sodium bicarbonate hydration prior to CTPA in patients with chronic kidney disease (CKD). We performed an open-label ...
Ishigami Junichi J Department of Nephrology, Shuuwa General Hospital, Saitama, Japan; Department of Nephrology, Tokyo Medical and Dental University, Tokyo, - - 2014
Estimating fluid balance in hemodialysis patients is essential when determining dry weight, but limited methods are currently available. B-type natriuretic peptide is a useful surrogate marker in patients with congestive heart failure (CHF), but whether its validity could be generalized to hemodialysis patients has not been studied well. 457 hemodialysis ...
Fujiwara Takashi T Department of Otolaryngology Head and Neck Surgery, Ehime University, Toon City, Ehime, - - 2014
To assess the diagnostic accuracy of lateral neck radiographs (LNR) for acute supraglottitis in adults. A single centre prospective observational study. Emergency department at Kurashiki Central Hospital, Japan. Adult patients who underwent LNR to detect supraglottitis. Presence of supraglottitis, based on nasopharyngeal laryngoscopy or a follow-up telephone call, 7-30 days after ...
Kallergis Eleftherios M EM Department of Cardiology, University Hospital of Heraklion, 71100 Heraklion, Crete, Greece - - 2014
Collagen turnover and atrial fibrosis have been implicated in the generation and perpetuation of atrial fibrillation (AF). We evaluated the importance of serum markers of collagen turnover in predicting the outcome of electrical cardioversion (CV) of persistent AF and the relationship between AF and fibrosis. Serum C-terminal pro-peptide of collagen ...
Di Mambro Corrado C Paediatric Arrhythmia Unit and Syncope Unit, Department of Paediatric Cardiology, Bambino Gesù Children's Hospital, IRCCS, Via Torre di Palidoro snc, 00050 Palidoro-Fiumicino (Rome), Italy - - 2014
Children and adolescents with ventricular pre-excitation (VPE) are at increased risk for sudden cardiac death (SCD). Although antiarrhythmic therapy and catheter ablation are well established temporary or definitive treatments for patients with Wolff-Parkinson-White (WPW) syndrome, the optimal management of children with asymptomatic VPE remains to be clearly defined. On the ...
Henry Timothy D TD Cardiology, Minneapolis Heart Institute - - 2014
Rationale: Ixmyelocel-T is associated with a wide range of biological activities relevant to tissue repair and regeneration. Objective: To evaluate the safety and efficacy of ixmyelocel-T in 2 prospective randomized Phase 2A Trials administered via mini-thoracotomy or intramyocardial catheter injections in patients with dilated cardiomyopathy (DCM) stratified by ischemic or ...
Chang Yi-Yao YY Cardiology Division of Cardiovascular Medical Center, Far Eastern Memorial Hospital, New Taipei City, - - 2014
Hypokalemia in primary aldosteronism (PA) patients correlates with higher levels of cardiovascular events and altered left ventricular geometry. However, the influence of aldosterone on microvascular endothelial function and the effect of hypokalemia on the vascular structure still remain unclear. We investigated the peripheral arterial functions, including the endothelial function of ...
Pottel Hans H Departments of aPublic Health and Primary Care at Kulak bDevelopment and Regeneration at Kulak, KU Leuven Kulak, Kortrijk Departments of cPaediatric Neurology dPaediatric Nephrology eNuclear Medicine, University Hospital Leuven Departments of fDevelopment and Regeneration gImaging and Pathology, KU Leuven, Leuven, - - 2014
Guidelines for measuring glomerular filtration rate (GFR) using Cr-EDTA require normalizing of GFR for body surface area (BSA) before applying the Bröchner-Mortensen (BM) correction. The guideline explicitly mentions the importance of performing BSA normalization before BM correction and that this is particularly important in children in whom the effects of ...
Hong Chae Moon CM aDepartment of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital bCenter of Biostatistics, School of Medicine, Kyungpook National University, Daegu, Republic of - - 2014
The aim of this study was to validate the effectiveness of delayed risk stratification (DRS) in predicting structural progression and compare the predictive value of American Thyroid Association (ATA) risk stratification with that of DRS in patients with differentiated thyroid cancer (DTC). A total of 398 patients with DTC who ...
Sung Jia-Ying JY Department of Neurology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, - - 2014
The aim of this study was to evaluate changes in sensory axonal excitability in the distal nerve in patients with cervical radiculopathy. The patients were classified by the findings of cervical MRI into two subgroups: 22 patients with C6/7 root compression and 25 patients with cervical cord and root compression ...
Carr Daniel F DF Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, - - 2014
Nevirapine, an NNRTI used in HIV treatment, can cause hypersensitivity reactions in 6%-10% of patients. In the most serious cases (1.3%) this can manifest as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). DNA samples were obtained and analysed from a total of 209 adult patients with nevirapine hypersensitivity (57 ...
El-Karaksy Hanaa - - 2014
Abstract Aim: To determine the individual fasting tolerance for patients with glycogen storage disease type III (GSD III) and to assess their linear growth velocity after tailoring of dose intervals of oral uncooked cornstarch. Patients and methods: A prospective cohort study included 32 patients with GSD III aged 6 months-11.5 ...
Pérez-Iglesias Rocio R Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK; CIBERSAM: Centro de Investigación Biomédica en Red en el área de Salud Mental Spain. Electronic address: - - 2014
This randomized open-label study compared the incidence of metabolic side effects of aripiprazole, ziprasidone and quetiapine in a population of medication-naïve first-episode psychosis patients. A total of 202 subjects were enrolled. Body weight, body mass index, leptin, fasting lipids and fasting glycaemic parameters were measured at baseline and at 3months ...
Jeschek Philip P Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna; Quality Assurance Working Group of the Austrian Society of Gastroenterology and - - 2014
Various types of liver disease are associated with an increased prevalence of colorectal adenomas. We investigated whether cirrhosis is risk factor for colorectal neoplasia by analyzing colonoscopy findings from 2 cohorts of patients awaiting liver transplantation. We performed a retrospective analysis to compare findings from CRC screening of 567 adult ...
Leite Hugo Fraga Barbosa HF Postgraduation Program of Neurology, Universidade Federal do Estado do Rio de Janeiro UNIRIO, Rio de Janeiro, - - 2014
Multiple sclerosis (MS) is a demyelinating disease and is considered the most debilitating neurological disorder among young adults. Sudden deafness has been reported in MS patients. This article describes cases of sudden deafness related to acute bouts in MS patients. A survey was conducted using 405 records of MS patients ...
Morales-Muñoz Isabel I Laboratory of Clinical Psychophysiology, Department of Psychiatry, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041 Madrid, Spain; Department of Psychiatry, Hospital Universitario 12 de Octubre, Madrid, Spain; Department of Psychiatry, School of Medicine, Complutense University of Madrid, Madrid, Spain. Electronic address: - - 2014
Cannabis-induced psychotic disorder (CIPD) refers to psychotic symptoms that arise in the context of cannabis intoxication. Prepulse inhibition (PPI) deficits have been extensively identified in schizophrenia and in cannabis abusers. We aimed to characterize PPI in CIPD patients. We used a sample of 48 CIPD patients, 54 schizophrenia patients and ...
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