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Jia Tie-Gang TG Department of Respiratory Medicine, First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei 075061, - - 2014
To explore the serum levels of IL-32, MMP-9,PCT and CRP in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A total of 50 patients with AECOPD and 45 cases with acute asthma attack admitted from October 2013 to August 2014 were selected, and the serum levels of IL-32, ...
Nair Satheesh S From the University of Tennessee Health Sciences Center, Methodist University Transplant Institute, Memphis, TN, 38104 - - 2014
Severe cholestasis after liver transplant is common. In this study, our aim was to develop an algorithm to guide biliary intervention in these patients. A retrospective review was performed on patients who had undergone a hepatobiliary scan, with or without subsequent endoscopic retrograde cholangiogram, during the immediate postoperative period. These ...
Chaabouni Khansa K Laboratoire de biochimie, Centre hospitalo-universitaire H. Bourguiba, Sfax, Tunisie, Unité de recherche bases moléculaires de la pathologie humaine, Faculté de médecine, Sfax, - - 2014
This study aims to evaluate the impact of androgen therapy on metabolic and inflammatoy profiles in male hypogonadic patients. Forty cases with isolated hypogonadism and 80 controls were enrolled. Clinical data were collected (age, weight, height, waist circonference and androgenothearapy). Blood tests were performed to evaluate testosterone, homeostasis index modal ...
Jiang Bo - - 2014
BackgroundVascular cognitive impairment-no dementia (VCIND) refers to the early or mild cognitive impairment induced by cerebral vascular injury. Research shows that serum total homocysteine (tHcy) level is an independent risk factor for cerebral vascular disease and may be closely related to cognitive function.Current studies on the tHcy level in VCIND ...
Stewart Lauren K LK Indiana University School of Medicine, Indianapolis, IN, USA, - - 2014
Acute pulmonary embolism (PE) can diminish patient quality of life (QoL). The objective was to test whether treatment with tenecteplase has an independent effect on a measurement that reflects QoL in patients with submassive PE. This was a secondary analysis of an 8-center, prospective randomized controlled trial, utilizing multivariate regression ...
Prapasrivorakul Siriluck S Oxford Pelvic Floor Centre, Department of Colorectal Surgery, Churchill Hospital, Oxford University Hospitals, Oxford, OX3 7LJ, - - 2014
High-grade internal rectal prolapse appears to be one of the contributing factors in the multifactorial origin of faecal incontinence. Whether it affects the outcome of sacral neuromodulation is unknown. We compared the functional results of sacral neuromodulation for faecal incontinence in patients with and without a high-grade internal rectal prolapse. ...
Manceau Philippe - - 2014
BackgroundThe clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNß) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective multicentre study to assess the association between response ...
Stoll Matthew L - - 2014
IntroductionPrior studies have established altered microbiota and immunologic reactivity to enteric commensal organisms in inflammatory bowel disease (IBD). Since intestinal inflammation is present in a subset of patients with both pediatric and adult spondyloarthritis (SpA), we hypothesized that SpA patients may also have altered microbiota and immune responsiveness to enteric ...
Heimans L L Department of Rheumatology, Leiden University Medical Center, PO BOX 9600, 2300 RC, Leiden, Netherlands, - - 2014
The aim of this study is to test the performance of a matrix model to predict rapid radiological progression (RRP) in a study population of early rheumatoid arthritis (RA) or undifferentiated arthritis (UA) patients. A matrix model using baseline CRP, erosion score, autoantibody status, and initial treatment choice to predict ...
Checa Angel A Division of Rheumatology, Drexel University College of Medicine, 219 N Broad, Philadelphia, PA, 19107, USA, - - 2014
Internal derangement of the knee secondary to a meniscal tear has been recently observed in patients with chondrocalcinosis. However, there is no data about the prevalence of meniscal tears associated to chondrocalcinosis. Therefore, the aim of this study was to know the rates of meniscal tear in patients with chondrocalcinosis. ...
Kropp Peter P Institute of Medical Psychology and Medical Sociology, Medical Faculty, University of Rostock, Gehlsheimer Straße 20, 18147, Rostock, Germany, - - 2014
Cortical habituation in episodic migraine patients without medication overuse headache (MOH), recorded by contingent negative variation (CNV), is often reduced compared with healthy controls. There is evidence that with longer duration of migraine disease (DOD) amplitudes and habituation of CNV become progressively abnormal. The aim of the study was to ...
Aksu O O Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Suleyman Demirel University, School of medicine, 3200, Isparta, Turkey, - - 2014
The association of obstructive sleep apnea syndrome (OSAS) and metabolic syndrome (MS) has been demonstrated in studies and in recent years; the effect of OSAS on insulin resistance independent of the level of obesity is being investigated. Nesfatin-1 is a newly defined 82 amino acid protein with a precursor molecule ...
Cucchetto G G Istituto di Malattie Infettive, Università di Verona, Verona, Italy, - - 2014
Chronic pulmonary aspergillosis (CPA) is a rare disease that primarily affects subjects with moderate immunodepression and/or structural alterations in the lung. Data for patients with probable CPA were collected over 24 months. Patients with probable CPA received oral voriconazole, and clinical, laboratory and radiological follow-up was performed at 3, 6 and ...
He Yun-Yun YY Department of Cardiology, Chinese PLA General Hospital, Beijing China; School of Medicine, Nankai University, Tianjin - - 2014
S100A12 has been proposed as a novel pivotal factor in inflammation produced by granulocytes. The purpose of this study was to investigate the relationship between S100A12 and chronic heart failure (CHF). One hundred and seventy-seven patients with CHF and 66 subjects without CHF were included in this study. Plasma levels ...
Claassen Daniel O DO Department of Neurology, Vanderbilt University, Nashville, Tennessee. Electronic address: - - 2014
Parkinson Disease (PD) patients treated with Dopamine Agonist therapy can develop maladaptive reward-driven behaviors, known as Impulse Control Disorder (ICD). In this study, we assessed if ICD patients have evidence of motor-impulsivity. We used the stop-signal task in a cohort of patients with and without active symptoms of ICD to ...
Kuragano Takahiro T Department of Internal Medicine, Division of Kidney and Dialysis, Hyogo College of Medicine, Hyogo - - - 2014
We evaluate the effect of the protoconized anemia therapy on adverse events using the Hb and ferritin levels of individual patients undergoing maintenance hemodialysis (MHD). Design: A randomized, parallel group, multi-center study. Two hundred sixty-six MHD patients. Intervention group: The doses of erythropoietin, iron, and vitamin C were adjusted every ...
Mazeron Renaud R Department of Radiation Therapy, Gustave Roussy Cancer Campus Grand Paris, Villejuif, France; Department of Molecular Radiotherapy-UMR1030, Gustave Roussy Cancer Campus Grand Paris, Villejuif, France. Electronic address: - - 2014
To evaluate the efficiency and potential implications of the lowest dose evaluated in the maximally exposed 2cm(3) of the bladder/dose evaluated at the International Commission for Radiation Units and Measurements (ICRU) bladder point (D2cm(3)/DICRU) ratio as surrogate to locate the D2cm(3) in patients treated with MRI-guided adaptive brachytherapy for cervical ...
Veronese Nicola N Department of Medicine, DIMED, Geriatrics Section, University of Padova, Padova, - - 2014
In anorexia nervosa (AN), osteoporosis and osteopenia are common, which have been associated with low circulating levels of vitamin D (VitD) in other settings. We aimed to meta-analyze cross-sectional studies reporting on VitD parameters in patients with AN and healthy controls (HCs). Electronic PubMed search from database inception until December ...
Shimizu Kentaro K Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. Electronic address: - - 2014
The gut is an important target organ after severe insult. Gut microbiota have an important role in immune response. However, the gut microbiota and environment have not been clarified in patients with burns. Therefore, we serially evaluated the gut microbiota and environment in patients with major burns. Fecal samples from ...
McPherson Stuart S Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, United Kingdom; Liver Unit, Newcastle Upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne, United Kingdom. Electronic address: - - 2014
There remains uncertainty about the natural history of non-alcoholic fatty liver disease (NAFLD). The spectrum of NAFLD includes non-alcoholic fatty liver (NAFL; steatosis without hepatocellular injury) and steatohepatitis (NASH; steatosis with hepatocyte ballooning degeneration +/- fibrosis). Our aim was to assess the histological severity of NAFLD in a cohort with ...
Carroccio Antonio - - 2014
BackgroundNon-celiac gluten sensitivity (NCGS) or `wheat sensitivity¿ (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS. Our study aims to evaluate the prevalence of low BMD in NCWS patients and search for correlations with other ...
Idilman R R Department of Gastroenterology, Ankara University School of Medicine, Ankara, - - 2014
The aim of this study was to determine the long-term efficacy of entecavir (ETV) and tenofovir disoproxil fumarate (TDF) on the natural course of disease in chronic hepatitis B patients (CHB) with/without cirrhosis in clinical practice. A total of 355 treatment-naïve CHB patients were enrolled into the study. The primary ...
Tokumaru Sheri S 1University of Hawaii at Hilo Daniel K. Inouye College of Pharmacy College of Pharmacy , Honolulu, Hawaii , United States Email: - - 2014
Background: Not all patients with warfarin-related acute intracranial hemorrhage (ICH), achieve full reversal of international normalized ratio (INR) after the first dose of weight-based prothrombin complex concentrate (PCC). We sought to identify factors associated with anticoagulation reversal failure after the first dose of PCC. Methods: Consecutive patients who were hospitalized ...
Pardo Manuel M Assistant Professor, Nursing Department. Faculty of Nursing. San Antonio Catholic University. Murcia. - - 2014
Objective: to evaluate the superiority of transcutaneous oxygen pressure (TcPO2) before, during, and after peripheral transluminal angioplasty (PTA) in comparison with ankle brachial index (ABI) in diabetic patients. Methods: 40 consecutive diabetic patients treated by PTA where included. This study show results before, during, and after PTA and their progression ...
Aghakhani Yahya Y Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, - - 2014
We explored the association between magnetic resonance imaging (MRI) lesion, degree of seizure laterality on intracranial electroencephalography (iEEG), and seizure outcome in patients with ambiguous or presumed bilateral temporal lobe epilepsy (BiTLE) on scalp EEG. We systematically reviewed the literature using Embase and MEDLINE up to May 31, 2012. Patients ...
Yamada Kozue K Departments of Pathology, Fukuoka University, Fukuoka, - - 2014
To analyse the clinicopathological characteristics and prognosis of 40 rheumatoid arthritis (RA) patients with methotrexate (MTX)-associated large B-cell lymphoproliferative disorders (MTX-BLPD). Soluble interleukin 2 receptor titres (median 1500 U/ml) in 40 patients with MTX-BLPD were lower than those of 24 RA patients with non-MTX- associated (non-MTX) BLPD (5731 U/ml) and ...
Yalamanchali Sreeya S Advanced Center for Specialty Care, Advocate Illinois Masonic Medical Center, Chicago, Illinois, - - 2014
To determine the effect of treatment of obstructive sleep apnea (OSA) with custom-made mandibular advancement devices (MADs) on C-reactive protein (CRP) levels in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS). Case series with chart review. Charts of consecutive patients fitted with custom-made mandibular advancement devices for treatment of OSAHS between ...
Zhao Pan P Clinical Trial Center, Beijing 302 Hospital (PLA 302 Hospital) , Beijing 100039 , - - 2014
Abstract Background. The disease progression of patients with primary biliary cirrhosis (PBC) varies significantly, and the prognostic markers that identify those patients who will develop liver failure have been scarcely studied from a Chinese cohort. Aims. We aimed to determine the predictive factors of liver failure in patients with PBC. ...
Kim Gi-Wook - - 2014
Objective The aim of this study was to determine the efficacy of measuring the diameter and area of the rectum using ultrasonography as an additional parameter for the evaluation of neurogenic bowel in patients with spinal cord injury (SCI). Participants In total, 32 patients with SCI (16 patients with upper ...
Calabrese Massimiliano M Neurology Section, Department of Neurological and Movement Sciences - - 2014
Although cognitive dysfunction is a relevant aspect of multiple sclerosis (MS) from the earliest disease phase, cognitive onset is unusual thus jeopardizing early and accurate diagnosis. Here we describe 12 patients presenting with cognitive dysfunction as primary manifestation of MS with either mild or no impairment in non-cognitive neurological domains. ...
Okamatsu Hideharu H Division of Arrhythmia and Electrophysiology, National Cerebral and Cardiovascular - - 2014
Background:The relationship between outcome of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) and the severity of left ventricular (LV) diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM) remains unknown.Methods and Results:Twenty-two HCM patients (12 female, aged 65±11 years) with paroxysmal (n=5; 23%) or persistent (n=17; 77%) AF were enrolled. LV diastolic ...
Jaskiewicz Filip F Intensive Cardiac Therapy Clinic, Medical University of Lodz. - - 2014
Many reports shown that for patients with acute coronary syndrome (ACS) increased admission blood glucose (ABG) level has been associated with adverse outcomes. Although scientific reports on this issue are still inconsistent, many recent studies confirm that hyperglycemia is also an unfavorable prognostic factor in patients with ACS complicated by ...
Li Qiaowen Q Department of Cardiology, The Medical College of Jinan University, Qingyuan City People's Hospital, Guangzhou, Guangdong, - - 2014
Studies suggested that the activation of the coagulation system and inflammation mutually may reinforce each other in some cases. In this study, we test the plasma tissue factor (TF) and interleukin 18 in patients with coronary heart disease (CHD) before and after treatment and aim to determine whether this relationship ...
Goudie Andrew A Division of Cardiovascular and Diabetes Medicine, Division of Medical Science, Ninewells Hospital and Medical School, Dundee, DD1 9SY, - - 2014
The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among heart failure patients and it is possible that high-risk subgroups may benefit from anticoagulation (warfarin). We hypothesize that ...
Behan Lucy Ann A LA L Behan, Endocrinology and Diabetes Metabolism, Beaumont Hospital, Dublin, - - 2014
Context and Objective: Patients with cranial diabetes insipidus (CDI) are at risk of developing both hypernatraemia and hyponatraemia, due to the condition itself, or secondary to treatment with vasopressin-analogues, or during administration of intravenous fluids. We aimed to assess the frequency and impact of dysnatraemias in the inpatient (INPT) and ...
Seko Yuya Y Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, - - 2014
Some cases with nonalcoholic fatty liver disease (NAFLD), particularly nonalcoholic steatohepatitis (NASH), can ultimately progress to liver cirrhosis. However, studies to clarify factors predictive of histological change in patients with NASH remain scarce. Our aim is to determine predictors of histological progression in Japanese patients with biopsy-proven NASH. This retrospective ...
Seril Darren N DN Departments of *Gastroenterology/Hepatology and †Rheumatic and Immunologic Disease, the Cleveland Clinic Foundation, Cleveland, - - 2014
Chronic antibiotic-refractory pouchitis (CARP) occurs more frequently in patients with ileal pouch-anal anastomosis (IPAA) with concomitant autoimmune disorders. The aim of this study was to assess the overlap between dysregulated immune features in patients with IPAA and their association with CARP. We identified 150 symptomatic patients with IPAA who met ...
Prabhakar Nidhi N Department of Radiodiagnosis, PGIMER, Chandigarh 160012, - - 2014
Patients with ulcerative colitis require recurrent conventional colonoscopy (CC) to define the extent of the disease. Computed tomography (CT) colonography (CTC) can be used as an alternative technique for studying the colon in these patients. The purpose of the study was to compare the findings of CTC to CC in ...
Lee Seung-Jun SJ Cardiology Division, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of - - 2014
Bleeding is a major concern in treatment of atrial fibrillation (AF) with vitamin K antagonist (VKA). This concern is more emphasized in patients with high bleeding risk such as liver cirrhosis (LC). We retrospectively analyzed incidence of stroke and major bleeding in 321 AF patients with LC, including early [Child-Pugh ...
Feben Candice C Division of Human Genetics, National Health Laboratory Service and School of Pathology, The University of the Witwatersrand, Johannesburg, South Africa. Electronic address: - - 2014
Fanconi anemia (FA) is a rare disorder of DNA repair, associated with various somatic abnormalities but characterized by hematological disease that manifests as bone marrow aplasia and malignancy. The mainstay of treatment, in developed nations, is hematopoietic stem cell transplantation (HSCT) with subsequent surveillance for solid organ and non-hematological malignancies. ...
Sriganesh Kamath K Department of Neuroanaesthesia, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, 560029, India, - - 2014
Subarachnoid hemorrhage is an acute neurological emergency requiring urgent confirmation of the diagnosis for planning definitive management. Due to altered consciousness, most patients require sedation for conducting this procedure smoothly. Currently, it is unclear if any one particular sedative drug has a favorable profile in patients undergoing cerebral angiography. The ...
Agmon-Levin Nancy N The Zabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, 52621, Tel Hashomer, - - 2014
Vitamin D immune-modulating effects were extensively studied, and low levels have been linked with autoimmune diseases. The associations of vitamin D with autoimmune diseases of the liver, and particularly primary biliary cirrhosis (PBC), are yet to be defined. Hence, in this study, serum levels of vitamin D were determined in ...
Amital Howard H Sackler Faculty of Medicine, Tel-Aviv University, 52621, Tel Aviv, Israel, - - 2014
Patients with autoimmune diseases often present with olfactory impairment. The aim of the study was to assess the olfactory functions of female patients with fibromyalgia (FM) compared with patients with systemic sclerosis (SSc) and with healthy female controls. Olfactory functions were assessed in 24 patients with FM, 20 patients with ...
Okamura Hideo H Department of Cardiovascular Medicine, National Cerebral and Cardiovascular - - 2014
Background:Risk stratification in patients with Brugada syndrome for primary prevention of sudden cardiac death is still an unsettled issue. A recent consensus statement suggested the indication of implantable cardioverter defibrillator (ICD) depending on the clinical risk factors present (spontaneous type 1 Brugada electrocardiogram (ECG) [Sp1], history of syncope [syncope], and ...
Swisher Christa B CB 1Department of Medicine (Neurology), Duke University Medical Center and 2Neurodiagnostic Center, Veterans Affairs Medical Center, Durham, - - 2014
To identify the probability of detecting non-convulsive seizures (NCS) based on the initial pattern seen in the first 30 minutes of continuous EEG (cEEG) monitoring. cEEG monitoring reports from 243 adult patients were reviewed, assessing the baseline cEEG monitoring pattern and the presence of seizures during the entire monitoring period. ...
Farlow Martin R MR *Department of Neurology, Indiana University School of Medicine, Indianapolis, IN †Department of Neurology and Psychiatry, St Louis University School of Medicine, St Louis, MO ‡Division of Neurology, Nova Southeastern University, Fort Lauderdale, FL §Novartis Pharmaceuticals Corporation, East Hanover, - - 2014
The long-term safety, tolerability, and efficacy of high-dose 13.3 mg/24 h rivastigmine patch in severe Alzheimer disease was evaluated in a 24-week, open-label extension to the double-blind ACTION study. Safety and tolerability, and efficacy on the Alzheimer's Disease Cooperative Study-Activities of Daily Living scale-Severe Impairment Version (ADCS-ADL-SIV), Severe Impairment Battery ...
Kim Tae-Wook TW Department of Dermatology, Pusan National University School of Medicine, Busan, - - 2014
The scalp is frequently affected in psoriasis patients, and pruritus can adversely affect the quality of life of affected patients. Few studies have assessed pruritus in scalp psoriasis. To determine the correlation among the clinical characteristics of pruritus, psoriasis scalp severity index (PSSI), and intraepidermal nerve fiber (IENF) density in ...
Lee Noo Ri NR Department of Dermatology, Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, - - 2014
Alopecia areata (AA) is a common dermatologic condition with a broad spectrum of clinical features and age of onset, classically characterized by nonscarring patches of hair loss. In the past, early-onset (before adolescence) AA has been associated with various autoimmune diseases, especially atopic diseases and lupus erythematosus and demonstrates a ...
Butthep Punnee P Hematology Laboratory, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Electronic address: - - 2014
Serum EPO concentration is related primarily to the rate of erythrocyte production and, under the stimulation of hypoxia, increases exponentially as hemoglobin (Hb) decreased. The level of EPO was determined in 141 subjects including 43 normal, 44 thalassemic patients and 54 thalassemic trait subjects. The EPO level was significantly higher ...
Mirabel Mariana M INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. Electronic address: - - 2014
Data on infective endocarditis (IE) in Southeast Asia are scarce. To describe the clinical epidemiology of IE in Lao PDR, a lower middle-income country. A single centre retrospective study at Mahosot Hospital, Vientiane. Patients aged over 1year of age admitted 2006-2012 to Mahosot Hospital with definite or possible IE by ...
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