Search Results
Results 151 - 200 of 2856
1 2 3 4 5 6 7 8 9 10 >
Efimova Irina I Federal State Budgetary Scientific Institution Research Institute for Cardiology, Tomsk, - - 2014
The aim of the study was to estimate regional cerebral blood flow (rCBF) and cognitive function in patients with metabolic syndrome (MetS) before and after antihypertensive combination therapy. The study included 24 patients with MetS (average age 52.4±1.6 years). All patients underwent brain single-photon emission computed tomography with technetium-99m hexamethylpropyleneamine oxime ...
Flanagan Eoin P EP Department of Neurology, Mayo Clinic, Rochester, - - 2014
Short transverse myelitis (STM; <3 vertebral segments) is considered noncharacteristic of neuromyelitis optica (NMO) spectrum disorders (NMOSDs). Nonappreciation of the potential for STM to occur in NMOSD may lead to increased disability from delay in diagnosis and appropriate treatment. To determine the frequency of short lesions at the initial myelitis ...
Kamo Kenta K Department of Orthopaedic Surgery, Yamaguchi Red Cross Hospital , Yamaguchi , - - 2014
Objectives. We clarified the prevalence of spondyloarthritis (SpA) symptom in inflammatory bowel disease (IBD). Methods. We performed the questionnaire survey of SpA symptom in IBD patients on their office visit. Results. One hundred and thirty seven patients were evaluated. The SpA features group included 46 (33.6%) patients (32 Men). Among ...
Zardi Enrico Maria EM aDepartment of Clinical Medicine, 'Campus Bio-Medico' University, Rome bVI Department of Internal Medicine and Interventional Ultrasonography, Policlinico 'S. Matteo' Foundation, IRCCS, Pavia, - - 2014
Information is lacking on portal hypertensive gastropathy (PHG) in cirrhotics without varices; our aim it is to evaluate whether clinical and sonographic parameters are associated with PHG and may provide information suitable for the management of these patients. After endoscopic selection of 145 cirrhotics without varices, 75 with PHG and ...
Porcelli Brunetta B Department of Medical Biotechnologies, Biochemistry Division, University of Siena, Siena, - - 2014
Celiac disease (CD) is an immune-mediated intolerance to dietary gluten, affecting genetically predisposed individuals. ELISA-based serological tests help to decide if further duodenal biopsy is necessary, for this the diagnostic kits have to be accurate, specific, and sensible. In this study, we investigate the performance of an ELISA that uses ...
Lalosevic Jovan J Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade, - - 2014
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases that are most frequently caused by drugs. The purpose of this study was to summarize 20 years of experience with SJS and TEN in the largest dermatology clinic in Serbia. The study included 38 patients treated during the period 1993-2012. ...
Bogert James N JN Department of Surgery, University of Texas Medical School at Houston, Houston, TX, - - 2014
Resuscitation of the hemorrhaging patient has undergone significant changes in the last decade resulting in the concept of damage control resuscitation (DCR). Hemostatic resuscitation aims to address the physiologic derangements found in the hemorrhaging patient, namely coagulopathy, acidosis, and hypothermia. Strategies to achieve this are permissive hypotension, high ratio of ...
Kaufman Michael M MS Center, Carolinas Medical Center, 1010 Edgehill Road North, Charlotte, NC, 28207, USA, - - 2014
The objective of this study is to characterize the timing and extent of radiologic MS disease recurrence during the 24-week natalizumab treatment interruption period in RESTORE. RESTORE was a randomized, partially placebo-controlled exploratory study. Natalizumab-treated patients with no gadolinium-enhancing (Gd+) lesions at screening (n = 175) were randomized 1:1:2 to continue natalizumab ...
Coblijn Usha K UK Department of Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands, - - 2014
One of the long-term complications of laparoscopic Roux-and-Y gastric bypass (LRYGB) is the development of marginal ulcers (MU). The aim of the present study is to assess the incidence, risk factors, symptomatology and management of patients with symptomatic MU after LRYGB surgery. A consecutive series of patients who underwent a ...
Panegyres Peter K PK Neurodegenerative Disorders Research Pty Ltd, 4 Lawrence Avenue, 6005, West Perth, WA, Australia, - - 2014
Our aim is to elucidate the clinical variables associated with the development of manifest HD in patients with intermediate CAG repeat lengths. 2,167 participants were seen throughout 44 research sites in the United States, Canada or Australia over a five-year natural history observational study (2006-2011) (Trial # NCT00313495). The Chi-square ...
Latus J J Division of Nephrology, Department of Internal Medicine, Robert-Bosch Hospital, Auerbachstraße 110, 70376, Stuttgart, Germany, - - 2014
Nephropathia epidemica is a milder form of hemorrhagic fever with renal syndrome, caused by Puumala virus. The clinical picture is characterized by a rapid loss of renal function (acute kidney injury) and thrombocytopenia. The purpose of the current analysis was to compare the clinical course of patients presenting with or ...
Kimbrough Dorlan J DJ Johns Hopkins University, Baltimore, MD, - - 2014
Objective: To determine whether African-American (AA) multiple sclerosis (MS) patients exhibit more retinal damage and visual impairment compared to Caucasian-American (CA) MS patients. Methods: 687 MS patients (81 AA) and 110 healthy control (HC) subjects (14 AA) were recruited at three academic hospitals between 2008 and 2012. Using mixed effects ...
Shirakabe Akihiro A Division of Intensive Care Unit, Chiba Hokusoh Hospital, Nippon Medical - - 2014
Background:Different mechanisms of acute kidney injury (AKI) may exist for acute heart failure (AHF) patients compared with other patients.Methods and Results:We analyzed data from 282 patients with AHF. The biomarkers were measured within 30 min of admission. Patients were assigned to a no-AKI (n=213) or AKI group (Class R (n=49), Class I ...
Yu Wei-Kuang WK Department of Ophthalmology, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei, 11217, - - 2014
The aim of this study was to investigate clinical characteristics, outcome, and factors associated with response to systemic administration of steroids in patients with ocular adnexal immunoglobulin G4 (IgG4)-related disease. This was a retrospective evaluation of 11 patients with histopathologically verified ocular adnexal IgG4-related diseases at a medical center in ...
Nergiz Avcioglu Sümeyra S Department of Obstetrics and Gynecology, Adnan Menderes University School of Medicine , Aydin , Turkey - - 2014
Abstract Objective: Visfatin is one of the most recent proteins shown to be highly expressed in adipose tissue. The purpose of this study was to determine visfatin levels in patients with endometrial cancer (EC). Methods: A total of 90 patients (46 EC patients and 44 healthy controls) were included in ...
Shanmugam G Vijay GV Department of General Medicine, Pondicherry Institute of Medical Sciences , Ganapthychettikulam, Kalapet, Pondicherry , India - - 2014
Abstract There is an enormous increase in the burden of chronic kidney disease both in developing and developed countries. There is a paucity of data on obstructive sleep apnea (OSA) in chronic kidney disease (CKD) patients in India. We used a cross-sectional prospective observational study to determine the prevalence of ...
Camargo Cz C Rheumatology Division, Federal University of São Paulo , São Paulo , - - 2014
Objectives: To evaluate the morphological and functional abnormalities of the microcirculation associated with markers of vascular injury in patients with early systemic sclerosis (SSc). Method: Forty-six patients with early SSc were compared with 80 patients with definite SSc, 40 patients with primary Raynaud's phenomenon (PRP), and 45 healthy subjects. Widefield ...
Dushianthan Ahilanandan - - 2014
BackgroundAcute respiratory distress syndrome (ARDS) is a life-threatening critical illness, characterised by qualitative and quantitative surfactant compositional changes associated with premature airway collapse, gas-exchange abnormalities and acute hypoxic respiratory failure. The underlying mechanisms for this dysregulation in surfactant metabolisms are not fully explored. Lack of therapeutic benefits from clinical trials, ...
Matsumoto Hideyuki H Department of Neurology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo, 150-8935, Japan, - - 2014
The aim of this paper is to investigate cortical excitability in patients with end-stage renal disease receiving peritoneal dialysis (PD) without any symptoms suggestive of uremic encephalopathy. We performed transcranial magnetic stimulation for 52 PD patients and 28 normal subjects. We compared the active motor threshold (AMT), resting motor threshold ...
Yuan Shanshan S Department of Endocrinology, Peking University First Hospital, Beijing 100034, - - 2014
Objective: Sera of Hashimoto's thyroiditis (HT) patients are known to exhibit elevated levels of anti-thyroglobulin IgG (TgAb IgG). Therefore, TgAb IgG represents a hallmark of this debilitating autoimmune disease. The aim of our study was to investigate the differential expression of specific glycosylation patterns of TgAb IgG from HT patients ...
Notarnicola A A DIM-Rheumatology Unit, Medical School, University of Bari , - - 2014
Objectives: To assess the serum levels of interleukin (IL)-15 and IL-17 in patients with idiopathic inflammatory myopathies (IIM) and correlate them with levels of IL-1 receptor antagonist (IL-1ra), IL-6, IL-10, interferon (IFN)-γ, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1α, and MIP-1β. Possible correlations with disease activity parameters were also ...
Oliver Nora - - 2014
Abstract Acute leukemia patients develop venous thrombosis (VT) related to central venous catheters (CVC). Anticoagulation (AC) in these patients who are thrombocytopenic and often coagulopathic is challenging. To evaluate safety and efficacy of AC in treating CVC-related VT, we retrospectively compared outcomes of acute leukemia patients who were treated or ...
Schievink Wouter I WI Departments of - - 2014
OBJECT Spontaneous intracranial hypotension is an increasingly recognized cause of headaches. Pituitary enlargement and brain sagging are common findings on MRI in patients with this disorder. The authors therefore investigated pituitary function in patients with spontaneous intracranial hypotension. METHODS Pituitary hormones were measured in a group of 42 consecutive patients ...
Zhang Ning N Department of Medical Psychology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, 264 Guangzhou Road, Nanjing, 210029, - - 2014
In addition to motor symptoms, patients with Parkinson's disease (PD) may experience non-motor symptoms (NMS), more often with more advanced disease stage. However, the clinical feature of the NMS and potential risk factors that affect NMS in idiopathic PD patients remain unclear. 493 PD patients diagnosed with PD via the ...
Lopes Agnaldo José AJ Laboratory of Respiratory Physiology, State University of Rio de Janeiro, Brazil Rehabilitation Sciences Master's Program, Augusto Motta University Center, Rio de Janeiro, Brazil - - 2014
Bronchiectasis develops along the natural course of several respiratory and systemic conditions and induces significant changes in the morphofunctional structure of airways. Our objective was to assess the impact of various causes of bronchiectasis on clinical data, pulmonary function tests, and high-resolution computed tomography (HRCT). The present report was a ...
Probasco William W Department of Foot and Ankle Surgery, Hospital for Special Surgery, New York, - - 2014
Patients with adult-acquired flatfoot deformity (AAFD) develop peritalar subluxation, which may stem from valgus inclination of the inferior surface of the talus. We hypothesized that patients with AAFD would have an increased valgus tilt of the subtalar joint in the coronal plane compared to controls when assessed with a novel ...
Kataoka Yuko Y Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, - - 2014
Central diabetes insipidus (CDI), which is characterized by polyuria and polydipsia, is caused by a deficiency of the antidiuretic hormone arginine vasopressin (AVP). While CDI is treated with desmopressin, an analogue of AVP, the intranasal formulation is inconvenient and CDI patients reportedly prefer the oral formulation to the intranasal one. ...
Al-Maramhy Hamdi H Hamdi Al-Maramhy, Samer Sawalhi, Department of Surgery, College of Medicine, Taibah University, Al-Madina 30001, Saudi - - 2014
To assess levels of serum resistin upon hospital admission as a predictor of acute pancreatitis (AP) severity. AP is both a common and serious disease, with severe cases resulting in a high mortality rate. Several predictive inflammatory markers have been used clinically to assess severity. This prospective study collected data ...
Hedenus Michael M Department of Internal Medicine, Sundsvall Hospital, 851 86, Sundsvall, Sweden, - - 2014
This randomized trial evaluated ferric carboxymaltose without erythropoiesis-stimulating agents (ESA) for correction of anemia in cancer patients with functional iron deficiency. Patients on treatment for indolent lymphoid malignancies, who had anemia [hemoglobin (Hb) 8.5-10.5 g/dL] and functional iron deficiency [transferrin saturation (TSAT) ≤20 %, ferritin >30 ng/mL (women) or >40 ng/mL (men)], were randomized ...
Fabiá Valls M J - - 2014
Diagnostic management of suspected pulmonary embolism (PE) in patients with a history of venous thromboembolism (VTE) is complicated due to persistent abnormal D-dimer levels, residual embolic obstruction and higher clinical prediction rule (CPR) scores. We aimed to evaluate the safety and efficiency of the standard diagnostic algorithm consisting of a ...
van de Veerdonk Mariëlle C - - 2014
Even after years of stable response to therapy, patients with idiopathic pulmonary arterial hypertension (IPAH) may show an unexpected clinical deterioration due to progressive right ventricular (RV) failure. Therefore, the aim of this study was to assess in five-year clinically stable patients with IPAH whether initial differences or subsequent changes ...
Bilgiç Ozlem O Department of Dermatology - - 2014
Abstract Background: Prior studies have demonstrated lower serum zinc levels in acne vulgaris (AV) patients compared with controls. However, no study has investigated the relationship between AV and erythrocyte zinc levels, which is a superior indicator of body zinc levels. Additionally, the potential influence of isotretinoin use on body zinc ...
Haase Daniel D Department of Computer Science, Friedrich Schiller University, Jena, - - 2014
Aim of the present observational single center study was to objectively assess facial function in patients with idiopathic facial palsy with a new computer-based system that automatically recognizes action units (AUs) defined by the Facial Action Coding System (FACS). Still photographs using posed facial expressions of 28 healthy subjects and ...
Sun Wenxue W Department of Nephrology, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, - - 2014
The purpose of this study was to investigate the correlation of conjunctival and corneal calcification (CCC) with cardiovascular calcification in patients undergoing maintenance hemodialysis (MHD). A total of 122 patients undergoing MHD in our hospital were included in this study. Conjunctival and corneal calcification was examined by slit lamp and ...
Coutinho Jonathan M JM From the Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands (J.M.C., J.S.); Department of Neurology, Hospital Santa Maria, Lisboa, Portugal (P.C., J.M.F.); Department of Neurology, Instituto Nacional de Neurologia y Neurocirurgia, México City, México (F.B.); and Department of Neurology, Hôpital Lariboisière, Paris, France (M.-G.B.). - - 2014
Although headache is the most common symptom in cerebral venous thrombosis, 5% to 30% of patients do not report headache at baseline. Characteristics of these patients have not been investigated. In post hoc analysis of the International Study on Cerebral Vein and Dural Sinus Thrombosis study, patients who might not ...
Hannoush H H Cardiovascular and Pulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, - - 2014
Proteus syndrome (PS) is a rare, mosaic disorder with asymmetric and distorting overgrowth of the skeletal system, skin, and adipose tissues. Cardiac abnormalities are rare in this syndrome and only two prior cases have been reported. Many patients with PS followed at our institution underwent transthoracic echocardiograms for preoperative evaluation ...
Calcagno A A Unit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, - - 2014
In limited-resource settings monitoring antiretroviral treatment efficacy is restrained by the lack of access to technological equipment. Aim of the study was to assess the use of dried plasma (DPS) and blood spots (DBS) to facilitate ARV monitoring in remote settings where clinical monitoring is the primary strategy. A cross-sectional ...
Heble Daniel E DE Jr 1Department of Pharmacy, Children's Mercy Hospital, Kansas City, MO; 2Divison of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Hospital, Kansas City, MO; and 3University of Missouri-Kansas City School of Pharmacy, Kansas City, - - 2014
Metabolic alkalosis is a common acid-base disturbance occurring in critically ill pediatric patients. Acetazolamide and arginine hydrochloride are pharmacologic agents used at our institution for patients refractory to first-line therapy or those unable to tolerate fluid replacement. The objective of this retrospective review was to determine if a course of ...
Zhong H H Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, - - 2014
Allergen-specific immunotherapy (ASIT) is the main treatment for inducing long-term immunological and clinical tolerance in patients with IgE-mediated allergic diseases. Recent open-label and controlled studies on the efficacy of ASIT in patients with atopic dermatitis (AD) have provided promising results. However, data about possible relationship between the improvement of clinical ...
Spencer Hillard T HT Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Hunnewell 2, Boston, MA, 02115, USA, - - 2014
Variation in rib numbering has been noted in adolescent idiopathic scoliosis (AIS), but its effect on the reporting of fusion levels has not been studied. We hypothesized that vertebral numbering variations can lead to differing documentation of fusion levels. We examined the radiographs of 161 surgical AIS patients and 179 ...
Daniłowicz-Szymanowicz Ludmiła L Department of Cardiology and Electrotherapy, Medical University of Gdańsk. - - 2014
Patients with left ventricular ejection fraction (LVEF) ≤ 35% are eligible for implantable cardioverter-defibrillator (ICD) placement for the primary prevention of sudden cardiac death (SCD). This recommendation results in continuously growing waiting lists of patients who have been qualified for and are awaiting the procedure. Whiled reduced LVEF is a ...
Alawami M M Green Lane Cardiovascular services, Auckland City Hospital, Auckland, New - - 2014
Obesity is a risk factor for both Sleep Related Breathing Disorders (SRBD) including Obesity Hypoventilation Syndrome (OHS) and Cardio-Vascular Diseases (CVD). The development of CVD in patients with SRBD is usually attributed to the fact that most patients are obese in addition to conventional cardiovascular risk factors. A dataset of ...
He Wei W Department of Physical Medicine and Rehabilitation, The Affiliated Jiangyin People's Hospital of Southeast University Medical College, Wuxi, - - 2014
We conducted a meta-analysis of positron emission tomography (PET) findings in Alzheimer's disease (AD) and mild cognitive impairment (MCI) to clarify the changes underpinning these conditions. All studies that utilised the PET tracers Pittsburgh Compound-B (PIB) or 2-[18F]fluoro-2-deoxy-D-glucose (FDG) to investigate patients with MCI or AD, were considered for the ...
Domitrz Izabela I Department of Neurology, Medical University of Warsaw, Warsaw, - - 2014
A migraine is a common neurological disorder that often coexists with other illnesses including heart abnormalities, such as patent foramen ovale (PFO), atrial septal aneurysm (ASA), and mitral valve prolapse (MVP). The aim of our study was to evaluate the occurrence of some heart abnormalities in migraine patients by routine ...
Sundareswaran Shobha - - 2014
Objectives :  The aims of this study were to analyze the prevalence of sella turcica bridging and to measure the size of the sella turcica on profile cephalograms in a homogenous group of surgically repaired unilateral cleft lip and palate (UCLP) patients. Setting :  Tertiary care center. Design :  Retrospective ...
Richards Anthony A Sydney Gynaecology Oncology Group, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, - - 2014
To determine the effectiveness of vaginal estrogen cream to improve the rate of satisfactory colposcopy and subsequent smear result in patients in a hypoestrogenic state and an abnormal Papanicolaou smear. To delineate between abnormal smears secondary to atrophy and inflammation from preneoplastic change and suggest an effective treatment strategy to ...
Hsiang J C JC Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New - - 2014
Liver cirrhosis is an important cause of morbidity and mortality, however little is known about its impact in New Zealand. We aim to determine the disease burden, epidemiology and outcomes of cirrhotic patients METHODS: A retrospective study of patients with cirrhosis who sought care at a sole public hospital in ...
Caviglia Gian Paolo GP Department of Medical Sciences, University of Turin , Turin , - - 2014
Abstract Background. The clinical pictures of functional gastrointestinal disorders and inflammatory diseases can be quite similar leading to inappropriate and expensive investigations. Objective. To investigate fecal calprotectin (FC) diagnostic performance in different gastrointestinal conditions. Material and methods. Stool specimens of 66 outpatients referred for colonoscopy were collected for further FC ...
Cioffi Giovanni G Department of Cardiology, Villa Bianca Hospital, Trento, - - 2014
Early detection of left ventricular (LV) systolic dysfunction is pivotal in the management of patients with aortic stenosis (AS). LV circumferential and/or longitudinal shortening may be impaired in these patients despite LV ejection fraction is preserved. We focused on prevalence and factors associated with combined impairment of circumferential and longitudinal ...
Hong Hong H Department of Pathology, University Hospitals Case Medical Center, Cleveland, Ohio; Case Western Reserve University School of Medicine, Cleveland, - - 2014
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening diagnosis requiring prompt initiation of therapeutic plasma exchange (TPE). Measurement of immature platelet (PLT) fraction (%-IPF) differentiates PLT consumption or destruction from hypoproduction. Our study evaluated %-IPF changes over the course of TTP treated with TPE and as a measure of treatment efficacy. ...
1 2 3 4 5 6 7 8 9 10 >