Search Results
Results 101 - 150 of 2432
1 2 3 4 5 6 7 8 9 10 >
Wu L M LM Department of Surgery, University of Auckland, Auckland, New - - 2014
The gut is implicated in the pathogenesis of acute pancreatitis but there is discrepancy between individual studies regarding the prevalence of gut barrier dysfunction in patients with acute pancreatitis. The aim of this study was to determine the prevalence of gut barrier dysfunction in acute pancreatitis, the effect of different ...
Rosas José J Department of Rheumatology, Marina Baixa Hospital, Villajoyosa, Alicante, Spain. - - 2014
The aim of this paper is to assess the usefulness of measuring serum levels of adalimumab (ADL) and anti-ADL antibodies in 57 patients with rheumatoid arthritis (RA) treated with ADL for at least 3 months in daily practice. All patients received concomitant disease-modifying anti-rheumatic drug (DMARD). Receiver-operator characteristics (ROC) analysis ...
Sivula M M Intensive Care Units, Division of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, - - 2014
Matrix metalloproteinase-8 (MMP-8) and tissue inhibitor of metalloproteinases-1 (TIMP-1) have recently been suggested to be involved in coagulation process. Our objectives were to observe systemic MMP-8 and TIMP-1 levels in patients with severe sepsis with or without disseminated intravascular coagulation (DIC) and to study their relationship with coagulation markers over ...
Saguner Ardan M AM Department of Cardiology, University Heart Center - - 2014
Background:The clinical role of atrial fibrillation/atrial flutter (AF-AFl) and variables predicting these arrhythmias are not well defined in patients with arrhythmogenic right ventricular dysplasia (ARVD). We hypothesized that transthoracic echocardiography (TTE) and 12-lead electrocardiography (ECG) would be helpful in predicting AF-AFl in these patients.Methods and Results:ECGs and TTEs of 90 patients diagnosed ...
Gordon Monica - - 2014
IntroductionExternal ventricular drainage (EVD)-related ventriculitis is one of the most severe complications associated with the use of EVDs. Establishing an early and certain diagnosis can be difficult in critically ill patients. We performed this prospective study to evaluate the usefulness of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) determination ...
Tapolyai Mihály M Fresenius Medical Care Hungary, Semmelweis University, Budapest, Hungary; Carolinas Campus, Edward Via Osteopathic College of Medicine, Spartanburg, - - 2014
The authors examined the relationship between thiazide-type diuretics and fluid spaces in a cohort of hypertensive patients in a retrospective study of 60 stable hypertensive patients without renal abnormalities who underwent whole-body bioimpedance analysis. Overhydration was greater in the diuretic group, but only to a nonsignificant degree (5.9 vs 2.9%; ...
Talib Ahmed Karim AK Department of Cardiology, Asahikawa Medical University; Department of Laboratory Medicine, Asahikawa Medical - - 2014
We reported impaired QT-rate dependence in early repolarization syndrome (ERS); however, contemporary data have shown peak incidence of sudden cardiac death (SCD) in ERS and Brugada syndrome (BrS) at mid-night and early morning. Taken together, we analyzed the nocturnal QT-rate dependence in both syndromes. A total of 172 subjects were ...
Tian Ying - - 2014
The CpG island methylator phenotype (CIMP) of clear cell renal cell carcinomas (ccRCCs) is characterized by accumulation of DNA methylation at CpG islands and poorer patient outcome. The aim of this study was to establish criteria for prognostication of patients with ccRCCs using the ccRCC-specific CIMP marker genes. DNA methylation ...
Narang Neera S NS Division of Immunology and Rheumatology, Stanford University, Stanford, - - 2014
Objective: To identify clinical and serologic correlates of cutaneous ulcers in dermatomyositis (DM). Methods: We retrospectively examined a cohort of 152 DM patients. We compared the features of patients with ulcers to those without ulcers using chi-squared or Fisher's exact tests and used univariate and multivariate logistic regression models to ...
Mahan Susan T ST Departments of *Orthopaedics §Orthopaedic Surgery, Boston Children's Hospital †Department of Orthopaedic Surgery ∥Catharine Ormandy Professor of Orthopaedic Surgery, Harvard Medical School ‡Harvard Combined Orthopaedic Residency Program, Boston, - - 2014
There are little patient-reported data on functional outcomes of tarsal coalition resection in children and adolescents. The purpose of this study is to evaluate the medium-term (>2 y) outcomes in patients who have had surgical excision of their symptomatic tarsal coalition and to compare patient-based outcomes in patients who have ...
Hu Ching-Yun CY The Intensive Care Unit, Taichung Veterans General Hospital, Taichung, Taiwan, - - 2014
Acetazolamide-related hypophosphatemia leading to cardiac arrest is extremely rare. Herein we report a 78-year-old female glaucoma patient who developed general weakness and acute respiratory failure, followed by cardiac arrest 1 day after taking acetazolamide. The patient was successfully weaned from the ventilator after correction of hypophosphatemia and fully recovered. As ...
Jafarzadeh A A Neurology Research Center, Department of Neurology, Kerman University of Medical Sciences, Kerman, Iran, - - 2014
The regulatory T (Treg) cells play a major role in the control of the autoimmunity and inflammation, and IL-35 has been described as an immunosuppressive cytokine that is mainly produced by CD4(+) FOXP3(+) Treg cells. The aim of this study was to evaluate the serum levels of IL-35 and a ...
Berger Steve S Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, 3014, Bern, Switzerland, - - 2014
The clinical tests currently used to assess spinal biomechanics preoperatively are unable to assess true mechanical spinal stiffness. They rely on spinal displacement without considering the force required to deform a patient's spine. We propose a preoperative method for noninvasively quantifying the three-dimensional patient-specific stiffness of the spines of adolescent ...
Tscholl Philippe M PM Department of Orthopedic Surgery, Orthopedic University Hospital Balgrist, University of Zurich, Zurich, Switzerland, - - 2014
Increased tibial tubercle trochlear groove distance (TT-TG) is frequently associated with trochlear dysplasia (TD). Since the trochlear groove appears more distally in patients with TD compared to controls, it is unknown whether TT-TG might be comparable and meaningful. Fifty patients with TD were retrospectively analysed and compared to 52 age- ...
Wang Zhong-Xia ZX Department of Graduate School, 301 Hospital, Beijing, China; Integrative Medical Centre, 302 Hospital, Beijing, - - 2014
Caroli's disease (CD) is a rare congenital disorder. The early diagnosis of the disease and differentiation of types I and II are of extreme importance to patient survival. This study was designed to review and discuss observations in 30 patients with CD and to clarify the clinical characteristics of the ...
Verrotti Alberto A Department of Pediatrics, University of Perugia, Perugia, Italy, - - 2014
Prader-Willi syndrome is a multisystemic genetic disorder that can be associated with epilepsy. There is insufficient information concerning the clinical and electroencephalographic characteristics of epilepsy and the long-term outcome of these patients. The aim of this study is to describe seizure types, electroencephalographic patterns and long-term seizure outcome in Prader-Willi ...
Ishii Rui R Department of Cardiology, Osaka Medical College, Takatsuki-shi Daigaku-machi 2-7, Osaka, 569-8686, - - 2014
Elevated eosinophil count was shown to be associated with the development of cholesterol embolization syndrome, a potentially life-threatening condition, after catheter-based procedures. We investigated the association between stages of chronic kidney disease (CKD) and the absolute eosinophil count (AEC) among cardiac patients. CKD stages were determined solely on the estimated ...
Lim Jun Uk JU Department of Gastroenterology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul, - - 2014
Although current guideline recommends selective use of pre-endoscopic prokinetics to increase diagnostic yield in upper gastrointestinal bleeding (UGIB) patients, no data to guide the use of these drugs are available. We aimed to investigate predictive factors for endoscopic visibility and develop simple and useful strategies for pre-endoscopic prokinetics use in ...
Kang Yun-Seong YS Department of Internal Medicine, College of Medicine, Dongguk University Ilsan Hospital, Goyang, 410-773, Republic of - - 2014
CT-P13 is the first biosimilar monoclonal antibody to infliximab. However, the antibody was tested only in rheumatoid arthritis and ankylosing spondylitis, which demonstrated equivalence to the originator in efficacy, safety, and pharmacokinetic profile. Extrapolation of its efficacy and safety to other pathologies is tenuous. Interchangeability with its originator is another ...
Zhang Ruijie R Department of Medical Imaging, Jinan Military General Hospital, No.25, Shifan Road, Jinan, Shandong Province, China, - - 2014
The purpose of this investigation was to examine the association between cognition disorders and microstructural white matter (WM) changes in maintenance hemodialysis end-stage renal disease (ESRD) patients. Twenty-six maintenance hemodialysis ESRD patients and 28 healthy controls underwent diffusion tensor imaging (DTI), Mini Mental State Examination (MMSE), Trial Marking Test-A&B (TMT-A&B), ...
Yoshida Yuko Y Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, - - 2014
Although preoperative biliary drainage in jaundiced patients is controversial, external biliary drainage (EBD) is beneficial for infection control in patients with biliary cancers. When EBD is performed, additional bile replacement (BR) has the benefit of improving impaired intestinal barrier function, but the detailed mechanism remains unknown. We examined the effect ...
Vearrier David D Department of Emergency Medicine, Drexel University College of Medicine, 245 N. 15th St, Mail Stop 1011, Philadelphia, PA, 19102, USA, - - 2014
Phenol is a caustic that may cause cutaneous or gastrointestinal burns depending on the route of exposure. Significant absorption may result in systemic toxicity. We present a case of topical phenol exposure resulting in cutaneous burns and systemic phenol toxicity. A 9-year-old girl was exposed to Creolin®, a general-purpose disinfectant ...
Manfredi A A Rheumatology Unit, University of Modena and Reggio Emilia, Via del Pozzo, 71, 41121, Modena, Italy, - - 2014
Inflammatory myopathies (IM) are a group of muscle diseases occurring both in children and adults. Nailfold videocapillaroscopy (NVC) alterations are described in IM, but available data are discordant, including differences between polymyositis (PM) and dermatomyositis (DM). The aim of this study was to describe the capillaroscopic differences between PM and ...
Shoda Katsutoshi K Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, 465 Kawaramach Hirokoji Kajiicho, Kamigyo-ku, Kyoto, 602-8566, - - 2014
We used real-time quantitative polymerase chain reaction (rqPCR) to detect human epidermal growth factor receptor 2 (HER2) amplification in the circulating cell-free DNA (cfDNA) of patients with gastric cancer (GC), which shows the spatial and temporal intrinsic heterogeneity of HER2 expression/copy number during progression, for liquid biopsy and treatment monitoring. ...
Wagenmakers Maem M Department of Medicine, Division of Endocrinology, Radboud University Medical Centre, Geert Grooteplein 8, 6500 HB, Nijmegen, the - - 2014
Centripetal obesity is associated with systemic low-grade inflammation and an increased cardiovascular risk. Patients in long-term remission of Cushing's syndrome (CS) report persisting abdominal fat accumulation. However, this has previously not been adequately objectified. Therefore we investigated the adipose tissue distribution and adipocytokine profiles of patients in long-term remission of ...
Reibis Rona R Department of Cardiology, Klinik am See, Rüdersdorf, - - 2014
Abstract Background. We aimed to describe the contemporary management of patients with systolic chronic heart failure (CHF) during a cardiac rehabilitation (CR) stay and present outcomes with focus on lipids, blood pressure, exercise capacity, and clinical events. Methods. Comparison of 3,199 patients with moderately or severely impaired left ventricular ejection ...
Rak Michael M Max-Plank-Institute of Psychiatry, Munich, - - 2014
Nightmares are a frequent symptom in narcolepsy. Lucid dreaming, i.e., the phenomenon of becoming aware of the dreaming state during dreaming, has been demonstrated to be of therapeutic value for recurrent nightmares. Data on lucid dreaming in narcolepsy patients, however, is sparse. The aim of this study was to evaluate ...
Thunström Erik E Department of Molecular and Clinical Medicine, Institution of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, - - 2014
Obstructive sleep apnea (OSA) is common in patients with coronary artery disease (CAD). Enhanced vascular inflammation is implicated as a pathophysiologic mechanism but obesity is confounding. We aimed to address the association of OSA with inflammatory biomarkers in a nonobese cohort of revascularized patients with CAD and preserved left ventricular ...
Truin W W Department of Surgery, Máxima Medical Centre, Veldhoven, The Netherlands, - - 2014
The aim of this study was to compare the frequency of breast-conserving surgery (BCS) between early-stage invasive ductal (IDC) and invasive lobular breast cancer (ILC). Women with primary non-metastatic pT1 and pT2 IDC or ILC diagnosed between 1990 and 2010 were selected from the NCR. All patients underwent BCS or ...
Matsuba Yumiko Y Hals-, Nasen-, Ohrenklinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, - - 2014
To evaluate the clinical course of orbital complication using a standardised diagnostic pathway. Seventy-three patients with orbital complications underwent a multimodal diagnostic pathway comprising ENT examination, leucocytes/CRP, CT-/MRI-scanning and disease-related data. Twenty-nine patients suffered from rhinosinusitis, 28 from mucoceles, 13 patients from neoplasms and three patients from rheumatic disorders. Clinical ...
Akudugu John J Division of Radiobiology, Department of Medical Imaging and Clinical Oncology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, South Africa, - - 2014
To assay for uPA and PAI-1 in prostate tissue from 40 patients with prostatic disease and to examine the robustness of the correlation of the uPA/PAI-1 ratio with benign prostatic hyperplasia (BPH) and prostate cancer (PCa), previously identified in a different cohort of 62 patients. uPA and PAI-1 were extracted ...
Raouf Alaa A Department of Neurosurgery, Faculty of Medicine, Alexandria University, Champillion St., Elazaritta, Alexandria, - - 2014
Hydrocephalus is a very common disease in developing countries. Congenital aqueductal obstruction and post-inflammatory hydrocephalus come on the top of the list of causes of hydrocephalus. Till the recent introduction of cranial endoscopy and despite their frequent complications, shunts were considered as the mainstream treatment for this disease. Endoscopic third ...
Tremolaterra Fabrizio - - 2014
Fibromyalgia Syndrome (FMS) is a frequent comorbidity in Irritable Bowel Syndrome (IBS) patients with a higher functional bowel disorder severity index (FBDSI). We tested the possibility that mild to severe IBS patients without FMS would have a graduated visceral and somatic perception, and the presence of FMS would further enhance ...
Aghaebrahim Amin A Department of Neurology, Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, - - 2014
Previous studies have suggested that patients with wake-up stroke (WUS) may have superior outcomes compared with patients with a witnessed late time of onset after revascularization. We sought to test this hypothesis in patients with anterior circulation large vessel occlusion stroke (ACLVOS) treated with endovascular therapy beyond 8 h from time ...
Boltin Doron - - 2014
BackgroundRifaximin is a minimally absorbed antibiotic with high luminal activity, used to treat various gastrointestinal diseases. Although rifaximin has been proposed as first line treatment for small intestinal bacterial overgrowth (SIBO), few data are available regarding its efficacy in non-IBS subjects. We aimed to assess the ability of rifaximin to ...
Guinot Pierre-Grégoire PG From the Anaesthesiology and Critical Care Department, Amiens University Hospital, Place Victor Pauchet, Amiens, - - 2014
The ability to predict fluid responsiveness in spontaneously breathing patients under spinal anaesthesia is desirable. The objective of this study was to test whether variations in stroke volume (SV) in response to a fixed mini-fluid challenge (ΔSV100) measured by thoracic impedance cardiography (ICG) can predict fluid responsiveness in spontaneously breathing ...
Abdallah J J Division of Gastroenterology and Hepatology, The Esophageal and Swallowing Center, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, - - 2014
Length of Barrett's oesophagus (BE) is a risk factor for oesophageal cancer. The underlying mechanisms that determine BE length are not fully known. To determine if there is a correlation between obesity and length of BE. Using a population-based study, 381 patients diagnosed with Barrett's oesophagus between 1999 and 2013 ...
Kim Seok-Mo SM Thyroid Cancer Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
Background. This study aimed to investigate the outcomes of papillary thyroid cancer (PTC) patients with lateral neck metastasis (LNM) according to their permanent pathology report but negative frozen section findings who did not undergo lateral neck dissection (LND). Methods. Between September 2009 and December 2011, 575 patients at Gangnam Severance ...
Silva Alessandra Pawelec da AP Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Rio Grande do Sul, - - 2014
Oculo-auriculo-vertebral spectrum (OAVS) is considered to be a defect of embryogenesis involving structures originating from the first branchial arches. Our objective was to describe the clinical and cytogenetic findings from a sample of patients with the phenotype of OAVS. Cross-sectional study in a referral hospital in southern Brazil. The sample ...
Ho Li-Chun LC Division of Nephrology, Department of Internal Medicine, E-DA Hospital, Kaohsiung, - - 2014
Background: High serum cystatin C (CysC) has been associated with clinical risks independently of the glomerular filtration rate (GFR). This study aims to investigate the predictive power of CysC in patients with a negligible GFR. Methods: Patients on chronic hemodialysis or peritoneal dialysis were enrolled for measurement of CysC levels ...
Sato Eiichi E Department of Pathology, Dokkyo Medical University, Koshigaya - - 2014
The efficacy of tolvaptan for treating heart failure has already been shown. Adequate data relating to the effect of tolvaptan on the correlation of water balance in renal disease are not available. A retrospective study was conducted on the efficacy and adverse reactions of tolvaptan for treating nephrotic syndrome.The subjects ...
Takada Jun J Department of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan, - - 2014
Carbon dioxide (CO2) insufflation is effective for gastric endoscopic submucosal dissection (ESD). However, its safety is unknown in patients with pulmonary dysfunction. This study aimed to investigate the safety of CO2 insufflation during gastric ESD in patients with pulmonary dysfunction under conscious sedation. We analyzed 322 consecutive patients undergoing ESD ...
Fawzi Amani A AA Department of - - 2014
Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patients from an extended pedigree with ALS and GGGGCC hexanucleotide repeat expansion in the C9orf72 gene (C9-ALS) underwent neuro-ophthalmologic examination. Following death and tissue ...
Lupoli Ga G Department of Clinical Medicine and Surgery, University "Federico II", Via Pansini 5, 80131, Naples, - - 2014
Context: Thyroglobulin antibodies (TgAbs) are surrogate markers of disease recurrence or persistence in differentiated thyroid cancer (DTC). However the prognostic significance of TgAb heterogeneity in DTC has not been investigated. Objective: To evaluate the relationship between TgAb epitope specificities and clinical outcomes in DTC patients. Design: We studied 61 TgAb-positive ...
Siddique Iqbal I Department of Medicine, Faculty of Medicine, Kuwait University , Safat , - - 2014
Abstract Objective. Ulcerative colitis (UC) is generally considered a disease of the Caucasian populations in developed countries, but its incidence is increasing rapidly in many developing countries, including the Middle East. The objective of this study was to determine the clinical epidemiology of UC in Arabs. Material and methods. This ...
Hansen C K CK Department of Neurology, Bispebjerg University Hospital, Copenhagen, - - 2014
The frequency of acute large vessel occlusions in relation to clinical severity has not yet been established in a comprehensive, consecutive and unselected cohort of patients with hyper-acute cerebral ischemia. The aim of this study was to establish the frequency of acute large vessel occlusions and describe the relations to ...
Campello E - - 2014
The role of circulating microparticles (MP) of different origin and tissue factor (TF)-bearing in overweight and obese patients with and without metabolic syndrome is still a matter of debate. In a case-control study, the presence of hypercoagulability was evaluated in overweight and obese patients by measuring MP, thrombin generation (TG) ...
Pool Joan J Joan Pool, RN, MSE, BSN, CCRN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Margaret Dercher, RN, BSN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Belinda Hanson, RN, BSN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Linda Heiman, RN, BSN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Yan Li, MA Biostatistician, Saint Luke's Hospital of Kansas City, Missouri. Kim Schraeder, RN, BSN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Mary Pat Schultz, APRN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Shawna Ziglinski, RN, BSN Staff Nurse, Cardiovascular Recovery Unit and Cardiovascular Holding Unit, Saint Luke's Hospital of Kansas City, Missouri. Marci Ebberts, RN, BSN, CCRN Clinical Education Specialist, Saint Luke's Hospital of Kansas City, - - 2014
Maintaining patient comfort and avoiding complications after coronary angiography are important both to the patient and the nurse. Strict bed rest with the head of bed (HOB) completely flat is standard care for postprocedure positioning to decrease pressure on the femoral artery. This position is not thought to be the ...
Park Hee Kyung HK Department of Neurology, Inje University Ilsan Paik Hospital, Goyang, - - 2014
Background & Objective: Early-onset Alzheimer's disease (EOAD, onset age <65 years) may differ from late-onset Alzheimer's disease (LOAD) in terms of cognitive profiles and neuropsychiatric symptoms. There have been few studies for Korean EOAD patients using well-structured databases. Previous studies focusing on cognitive profiles between the two groups had a ...
Gonzalez-Duarte Alejandra - - 2014
Background: Cryptococcal meningitis (CM) is a rare condition in non-HIV patients. The clinical manifestations in patients with systemic lupus erythematosus (SLE) are often confused with immunological activity, resulting in delayed diagnosis. Aims: We describe the natural history and outcome of eight HIV-negative patients with SLE and confirmed CM. Results: Mean ...
1 2 3 4 5 6 7 8 9 10 >