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Fehring Thomas K TK OrthoCarolina Hip and Knee Center, 2001 Vail Avenue, Suite 200A, Charlotte, NC, 28209, USA, - - 2014
To determine the importance of MRI abnormalities in metal-on-metal (MoM) bearings, it is important to understand the baseline features of this diagnostic tool in conventional metal-on-polyethylene (MoP) bearings. What are the frequency, size, and types of MRI-documented adverse local tissue reactions in asymptomatic patients with MoP bearings? We recruited 50 ...
Fadini Gian Paolo GP University of Padova, Department of Medicine, Division of Metabolic - - 2014
Context. Acromegaly increases cardiovascular risk, possibly due to the high prevalence of classical risk factors. However, in vitro studies show a protective role of GH/IGF-1 on the endothelium. Objective. To investigate circulating endothelial progenitor cells (EPCs), a marker of vascular regeneration, in acromegalic patients and how they are affected by ...
Ling Chen C Department of Nephrology, Beijing Children's Hospital affiliated to Capital Medical University, West District Nan Li Shi Lu 56th, Beijing, 100045, - - 2014
Early diagnosis of minimal change disease (MCD) in nephrotic syndrome (NS) patients remains challenging. Doctors often make a diagnosis of MCD using invasive renal biopsy. CD80, a transmembrane protein, is present on podocytes in a number of experimental models of NS. Urinary CD80 levels are significantly elevated in MCD but ...
Domenis Danielle Ramos DR Federal University of Sergipe , Lagarto , - - 2014
Purpose: A common presentation of mitochondrial myopathies is chronic progressive external ophthalmoplegia (CPEO). Dysphagia is a complaint in about 50% of cases. Methods: This investigation evaluated pharyngeal transit in patients with CPEO. Videofluoroscopic swallowing evaluation was performed with paste, liquid and solid boluses in 14 patients with CPEO and in ...
Xiang Li L Li Xiang, Qiang Zhan, Xin-Hua Zhao, Ya-Dong Wang, Yang-Zhi Xu, Ai-Min Li, Wei Gong, Yang Bai, Fa-Chao Zhi, Si-De Liu, Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510000, Guangdong Province, - - 2014
To determine the miss rate for colorectal flat adenomas during colonoscopy and the risk factors. Flat adenomas are frequently missed during colonoscopy. However, the risk factors that influence their miss rates are unclear. This was a multicenter, retrospective study in which patients diagnosed with colorectal adenomas at a diagnostic colonoscopy ...
Wu Wen-Guang WG Wen-Guang Wu, Wen-Jie Zhang, Jun Gu, Ming-Ning Zhao, Ming Zhuang, Ying-Bin Liu, Xue-Feng Wang, Laboratory of General Surgery and Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai 200092, - - 2014
To describe an optimal route to the Braun anastomosis including the use of retrieval-balloon-assisted enterography. Patients who received a Billroth II gastroenterostomy (n = 109) and a Billroth II gastroenterostomy with Braun anastomosis (n = 20) between January 2009 and May 2013 were analyzed in this study. Endoscopic retrograde cholangiopancreatography ...
Trad Sélim S AP-HP, Internal Medicine department 2, Groupe Hospitalier Pitié Salpêtrière, 75013 Paris, France. Electronic address: - - 2014
The purpose of this study was to estimate the prevalence of monoclonal immunoglobulin (MIg) among patients with systemic sclerosis (SSc) according to method of detection (capillary electrophoresis or immunofixation) and to search for any related clinical correlations. Retrospective multicenter comparison of capillary electrophoresis and immunofixation results in SSc patients and ...
Ferreira Daniel D Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, - - 2014
New therapies with disease-modifying effects are urgently needed for treating Alzheimer's disease (AD). Nerve growth factor (NGF) protein has demonstrated regenerative and neuroprotective effects on basal forebrain cholinergic neurons in animal studies. In addition, AD patients treated with NGF have previously shown improved cognition, EEG activity, nicotinic binding, and glucose ...
Gallego-Jutglà Esteve E Data and Signal Processing Group, University of Vic - Central University of Catalonia, Vic, Catalonia, - - 2014
Despite recent advances, early diagnosis of Alzheimer's disease (AD) from electroencephalography (EEG) remains a difficult task. In this paper, we offer an added measure through which such early diagnoses can potentially be improved. One feature that has been used for discriminative classification is changes in EEG synchrony. So far, only ...
Cheung Eva W EW Department of Pediatrics, Division of Critical Care Medicine, Columbia University, New York, New York. Electronic address: - - 2014
We investigated the influence of coronary artery abnormalities on outcome in patients with pulmonary atresia/intact ventricular septum (PA-IVS) for planned single-ventricle palliation. Catheterization and medical records were reviewed in patients with PA-IVS for planned single-ventricle palliation at our institution between 2000 and 2012. Primary outcome was death or transplantation. Patients ...
Testani Jeffrey M JM Department of Internal Medicine and Program of Applied Translational Research, Yale University School of Medicine, New Haven, Connecticut. Electronic address: - - 2014
Differentiating heart failure (HF) induced renal dysfunction (RD) from intrinsic kidney disease is challenging. It has been demonstrated that biomarkers such as B-type natriuretic peptide (BNP) or the blood urea nitrogen to creatinine ratio (BUN/Creat) can identify high vs. low risk RD. Our objective was to determine if combination these ...
Meneses Gdayllon Cavalcante - - 2014
We aimed to evaluate urinary MCP-1 and oxidative stress through urinary malondialdehyde (MDA) in leprosy and correlate them with traditional, but less sensitive markers of renal disease. This is a cross-sectional study of 44 patients with diagnosis of leprosy and no previous treatment. Skin smear was assessed through a bacteriological ...
Ofte Hilde K HK Nordland Hospital Trust, Norway - - 2014
Cluster headache (CH) attacks are accompanied by cranial autonomic symptoms indicative of parasympathetic hyperactivity and sympathetic dysfunction ipsilateral to the pain. We aimed to assess cranial autonomic function in CH patients during the remission phase of cluster headache. During a remission phase, 38 episodic CH patients underwent the following: dynamic ...
Kooiman J J Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the - - 2014
Hydration to prevent contrast induced-acute kidney injury (CI-AKI) induces a diagnostic delay when performing CT-pulmonary angiography (CTPA) in patients suspected of acute pulmonary embolism (PE). To analyze whether withholding hydration is non-inferior to sodium bicarbonate hydration prior to CTPA in patients with chronic kidney disease (CKD). We performed an open-label ...
Ishigami Junichi J Department of Nephrology, Shuuwa General Hospital, Saitama, Japan; Department of Nephrology, Tokyo Medical and Dental University, Tokyo, - - 2014
Estimating fluid balance in hemodialysis patients is essential when determining dry weight, but limited methods are currently available. B-type natriuretic peptide is a useful surrogate marker in patients with congestive heart failure (CHF), but whether its validity could be generalized to hemodialysis patients has not been studied well. 457 hemodialysis ...
Fujiwara Takashi T Department of Otolaryngology Head and Neck Surgery, Ehime University, Toon City, Ehime, - - 2014
To assess the diagnostic accuracy of lateral neck radiographs (LNR) for acute supraglottitis in adults. A single centre prospective observational study. Emergency department at Kurashiki Central Hospital, Japan. Adult patients who underwent LNR to detect supraglottitis. Presence of supraglottitis, based on nasopharyngeal laryngoscopy or a follow-up telephone call, 7-30 days after ...
Kallergis Eleftherios M EM Department of Cardiology, University Hospital of Heraklion, 71100 Heraklion, Crete, Greece - - 2014
Collagen turnover and atrial fibrosis have been implicated in the generation and perpetuation of atrial fibrillation (AF). We evaluated the importance of serum markers of collagen turnover in predicting the outcome of electrical cardioversion (CV) of persistent AF and the relationship between AF and fibrosis. Serum C-terminal pro-peptide of collagen ...
Di Mambro Corrado C Paediatric Arrhythmia Unit and Syncope Unit, Department of Paediatric Cardiology, Bambino Gesù Children's Hospital, IRCCS, Via Torre di Palidoro snc, 00050 Palidoro-Fiumicino (Rome), Italy - - 2014
Children and adolescents with ventricular pre-excitation (VPE) are at increased risk for sudden cardiac death (SCD). Although antiarrhythmic therapy and catheter ablation are well established temporary or definitive treatments for patients with Wolff-Parkinson-White (WPW) syndrome, the optimal management of children with asymptomatic VPE remains to be clearly defined. On the ...
Henry Timothy D TD Cardiology, Minneapolis Heart Institute - - 2014
Rationale: Ixmyelocel-T is associated with a wide range of biological activities relevant to tissue repair and regeneration. Objective: To evaluate the safety and efficacy of ixmyelocel-T in 2 prospective randomized Phase 2A Trials administered via mini-thoracotomy or intramyocardial catheter injections in patients with dilated cardiomyopathy (DCM) stratified by ischemic or ...
Chang Yi-Yao YY Cardiology Division of Cardiovascular Medical Center, Far Eastern Memorial Hospital, New Taipei City, - - 2014
Hypokalemia in primary aldosteronism (PA) patients correlates with higher levels of cardiovascular events and altered left ventricular geometry. However, the influence of aldosterone on microvascular endothelial function and the effect of hypokalemia on the vascular structure still remain unclear. We investigated the peripheral arterial functions, including the endothelial function of ...
Pottel Hans H Departments of aPublic Health and Primary Care at Kulak bDevelopment and Regeneration at Kulak, KU Leuven Kulak, Kortrijk Departments of cPaediatric Neurology dPaediatric Nephrology eNuclear Medicine, University Hospital Leuven Departments of fDevelopment and Regeneration gImaging and Pathology, KU Leuven, Leuven, - - 2014
Guidelines for measuring glomerular filtration rate (GFR) using Cr-EDTA require normalizing of GFR for body surface area (BSA) before applying the Bröchner-Mortensen (BM) correction. The guideline explicitly mentions the importance of performing BSA normalization before BM correction and that this is particularly important in children in whom the effects of ...
Hong Chae Moon CM aDepartment of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital bCenter of Biostatistics, School of Medicine, Kyungpook National University, Daegu, Republic of - - 2014
The aim of this study was to validate the effectiveness of delayed risk stratification (DRS) in predicting structural progression and compare the predictive value of American Thyroid Association (ATA) risk stratification with that of DRS in patients with differentiated thyroid cancer (DTC). A total of 398 patients with DTC who ...
Sung Jia-Ying JY Department of Neurology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, - - 2014
The aim of this study was to evaluate changes in sensory axonal excitability in the distal nerve in patients with cervical radiculopathy. The patients were classified by the findings of cervical MRI into two subgroups: 22 patients with C6/7 root compression and 25 patients with cervical cord and root compression ...
Carr Daniel F DF Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, - - 2014
Nevirapine, an NNRTI used in HIV treatment, can cause hypersensitivity reactions in 6%-10% of patients. In the most serious cases (1.3%) this can manifest as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). DNA samples were obtained and analysed from a total of 209 adult patients with nevirapine hypersensitivity (57 ...
El-Karaksy Hanaa - - 2014
Abstract Aim: To determine the individual fasting tolerance for patients with glycogen storage disease type III (GSD III) and to assess their linear growth velocity after tailoring of dose intervals of oral uncooked cornstarch. Patients and methods: A prospective cohort study included 32 patients with GSD III aged 6 months-11.5 ...
Pérez-Iglesias Rocio R Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK; CIBERSAM: Centro de Investigación Biomédica en Red en el área de Salud Mental Spain. Electronic address: - - 2014
This randomized open-label study compared the incidence of metabolic side effects of aripiprazole, ziprasidone and quetiapine in a population of medication-naïve first-episode psychosis patients. A total of 202 subjects were enrolled. Body weight, body mass index, leptin, fasting lipids and fasting glycaemic parameters were measured at baseline and at 3months ...
Jeschek Philip P Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna; Quality Assurance Working Group of the Austrian Society of Gastroenterology and - - 2014
Various types of liver disease are associated with an increased prevalence of colorectal adenomas. We investigated whether cirrhosis is risk factor for colorectal neoplasia by analyzing colonoscopy findings from 2 cohorts of patients awaiting liver transplantation. We performed a retrospective analysis to compare findings from CRC screening of 567 adult ...
Leite Hugo Fraga Barbosa HF Postgraduation Program of Neurology, Universidade Federal do Estado do Rio de Janeiro UNIRIO, Rio de Janeiro, - - 2014
Multiple sclerosis (MS) is a demyelinating disease and is considered the most debilitating neurological disorder among young adults. Sudden deafness has been reported in MS patients. This article describes cases of sudden deafness related to acute bouts in MS patients. A survey was conducted using 405 records of MS patients ...
Bandinelli Francesca F Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. - - 2014
To investigate radiological sacroiliac abnormalities in IBD patients without musculoskeletal symptoms and to determine the clinical and familiar differences between IBD patients with and without radiologic sacroiliac joint (SIJ) abnormalities. Subsequently, the patients with x-ray alterations were followed for 3 years in order to assess the onset of chronic inflammatory ...
Sen Hanim H Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The - - 2014
Patients with previous coronary artery bypass grafting (CABG) who underwent percutaneous coronary intervention (PCI) have an increased repeat revascularization rate, but data on contemporary second-generation drug-eluting stents (DES) are scarce. We evaluated 1-year clinical outcome following secondary revascularization by PCI in patients of the TWENTE trial and non-enrolled TWENTE registry, ...
Stellmann J P JP Institute for Neuroimmunology and Clinical MS Research (inims) and Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: - - 2014
Mobility assessment in Multiple Sclerosis (MS) is crucial for trials and individual patient counseling. Up to now, standard tests as the Timed 25-Foot Walk (T25FW) are restricted by floor effects in mildly disabled patients. The 3-meter Timed Tandem Walk (TTW) as a possibly more sensitive measure has not been investigated ...
Wu Jing Qin JQ School of Biomedical Sciences and Pharmacy, Faculty of Health, The University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; Schizophrenia Research Institute, Sydney, Australia; Psychiatry Research Center, Beijing HuiLongGuan Hospital, Peking University, Beijing, - - 2014
Free radical-mediated abnormalities may contribute to the development of tardive dyskinesia (TD) and specific aspects of schizophrenia symptomatology such as cognitive deficits. Superoxide dismutase (SOD), a critical enzyme in the detoxification of superoxide radicals, was found to be abnormal in TD. While most of previous studies focused on the manganese ...
Lebherz-Eichinger Diana D Department of Anesthesiology, General Intensive Care and Pain Medicine, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration, Medical University of Vienna, Vienna, Austria; RAIC Laboratory 13C1, Medical University of Vienna, Vienna, - - 2014
During chronic kidney disease (CKD) leukocytes attracted by chemokines can migrate into the kidney and further aggravate renal affliction by releasing proinflammatory and profibrotic factors. We therefore sought to investigate serum and urine chemokine levels of 114 patients with CKD and 21 healthy volunteers to examine their possible suitability as ...
Lianza Alessandro C AC Radiology Unit, Faculdade de Medicina da Universidade de Sao Paulo, Brazil. - - 2014
This paper aims to perform global assessment of long-term cardiac function in juvenile idiopathic arthritis (JIA) patients under TNF blockage therapy. Twenty-five polyarticular-course JIA patients pre-anti-TNF and 22 healthy controls underwent conventional/tissue Doppler echocardiography and cardiac biomarkers measurements (N-terminal pro-brain natriuretic peptide [NT-pro-BNP] and troponin T) at baseline (BL). Twenty-one ...
Köninger Angela A Department of Gynecology and Obstetrics, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany. Electronic address: - - 2014
Sonographic features of polycystic ovaries consist of elevated antral follicle count or ovarian volume of at least one ovary. The aim of this prospective cross-sectional study was to estimate intraindividual differences in sonographic measurements between the both ovaries of PCOS patients and controls and clinical consequences. Both ovaries of 85 ...
Kukla Piotr P Department of Cardiology, Specialistic Hospital, Gorlice, Poland. Electronic address: - - 2014
European recommendations on the management of acute pulmonary embolism (APE) divide patients into 3 risk categories: high, intermediate, and low. Mortality has previously been estimated at 3% to 15% in the intermediate group. The aim of this study was to use a new metric "ischemic electrocardiographic (ECG) patterns" to more ...
Taj Mehwesh M Department of Clinical Hematology, National Institute of Blood Disease Centre and Bone Marrow Transplantation(NIBD and BMT), - - 2014
To analyze patients suffering from aplastic anemia (AA, peripheral pancytopenia and hypocellular bone marrow in the absence of dysplasia, infiltration and fibrosis) for documenting patient's baseline characteristics and association with various human leucocyte antigens. An observational, cross-sectional study. The National Institute of Blood Disease (NIBD), Karachi, from March 2003 to ...
Pinazo María-Jesús MJ Barcelona Centre for International Health Research (CRESIB), Hospital Clínic i Provincial/IDIBAPS, Universitat de Barcelona, Barcelona, - - 2014
Digestive damage due to Chagas disease (CD) occurs in 15-20% of patients diagnosed as a result of peristaltic dysfunction in some endemic areas. The symptoms of chronic digestive CD are non-specific, and there are numerous confounders. Diagnosis of CD may easily be missed if symptoms are not evaluated by a ...
Gencer Meryem M Çanakkale Onsekiz Mart University, Medical Faculty, Department of Obstetric and Gynecology, Çanakkale, Turkey. Electronic address: - - 2014
In this study we aimed to investigate the relationship between lipocalin-2 (LCN2) levels and cardiovascular risk in patients with polycystic ovary syndrome (PCOS). Fifty patients with PCOS and 44 healthy women as controls were enrolled in the study. Laboratory and echocardiographic examinations were performed between the second and fifth days ...
Chen Yen-Fu YF *Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Yun-Lin; †Department of Pathology; ‡Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei; §Department of Molecular Biotechnology, Da-Yeh University, Chang-Hua; ‖Department of Oncology, National Taiwan University Hospital; and ¶Graduate Institute of Oncology Cancer Research Centre, National Taiwan University, Taipei, - - 2014
The prevalence, demographic features, and clinical outcomes of lung adenocarcinoma patients with novel ROS1 oncogenic rearrangement in East Asian populations are not clear. This study aimed to investigate the clinical and prognostic characteristics of lung adenocarcinoma in patients with ROS1 fusion compared with other driver mutations. Multiplex reverse transcription-polymerase chain ...
Abdelrahman Hisham S HS aMicrobiology Department, High Institute of Public Health bNeurology and Psychiatry Department, Faculty of Medicine, Alexandria University, Alexandria, - - 2014
Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system. Many diseases are associated with Epstein-Barr virus (EBV) infection, such as infectious mononucleosis and many types of malignancies, and it is thought to be related to some diseases of autoimmune origin, such as rheumatoid arthritis, systemic lupus erythematosis, ...
Li Jing J Department of Rheumatology and Clinical Immunology (JL, DX, WZ, YZ, XZ), Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing; Department of Rheumatology and Clinical Immunology (HW), Central Hospital of Jinhua, Zhejiang; Department of Rheumatology and Hematology (XH), The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning; MOE Key Laboratory of Protein Science (WL), School of Life Sciences, Tsinghua University, Beijing, - - 2014
To investigate the clinical features of Rhupus syndrome, we retrospectively reviewed the medical records of 56 patients with Rhupus who were hospitalized at the Peking Union Medical College Hospital, Beijing, China, between January 2000 and March 2013. We analyzed the clinical manifestations of Rhupus syndrome and compared these with a ...
Coutinho Gonçalo F GF Center of Cardiothoracic Surgery, University Hospital and Medical School, Coimbra, - - 2014
The timing for mitral valve surgery in asymptomatic patients with severe mitral regurgitation and preserved left ventricular function remains controversial. We analyzed the immediate and long-term outcomes of these patients after surgery. From January 1992 to December 2012, 382 consecutive patients with severe chronic degenerative mitral regurgitation, with no or ...
Heist E Kevin EK Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: - - 2014
Detect Fluid Early from Intrathoracic Impedance Monitoring (DEFEAT-PE) is a prospective, multicenter study of multiple intrathoracic impedance vectors to detect pulmonary congestion (PC) events. Changes in intrathoracic impedance between the right ventricular (RV) coil and device can (RVcoil→Can) of implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy ICDs (CRT-Ds) are used ...
Sun Byung Joo BJ Division of Cardiology, Cardiac Imaging Center, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, - - 2014
Although statins reduce cardiac events in hypertensive patients with cardiovascular risk factors, the effect of statins on coronary flow reserve (CFR) has not been examined. We tried to examine the effect of rosuvastatin on CFR in hypertensive patients at cardiovascular risk. CFR was studied in 56 hypertensive patients (40 men, ...
Fatemi Omid O Washington Hospital Center, Washington, District of Columbia; Georgetown University Hospital, Washington, District of Columbia; Washington DC Veteran's Medical Center, Washington, District of - - 2014
Atrial fibrillation (AF) is prevalent in patients with type 2 diabetes mellitus (DM) and is associated with markers of poor glycemic control; however, the impact of glycemic control on incident AF and outcomes is unknown. The aims of this study were to prospectively evaluate if intensive glycemic control in patients ...
Xu Yi Y Capital Medical University School of Stomatology, Beijing 100050, China. Electronic address: - - 2014
The aim of this study is to analyze the craniofacial morphology in patients with unrepaired isolated cleft palate (UICP) at childhood, adolescence and adulthood, in order to assess the influence of nonsurgical factors on the craniofacial growth in these patients. Lateral and posteroanterior cephalograms of 106 non-syndromic UICP patients and ...
Hammers Christoph M CM 0000000156312415 Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, - - 2014
Pemphigus vulgaris (PV) is a prototypic tissue-specific autoantibody-mediated disease, in which anti-desmoglein 3 (Dsg3) IgG autoantibodies cause life-threatening blistering. We characterized the autoimmune B-cell response over 14 patient years in two patients with active and relapsing disease, then in one of these patients after long-term remission induced by multiple courses ...
Higashi Fuyuhiko F Higashi Clinic, 589-1 Higashi-Honjou, Minabe-Cho, Hidaka-Gun, Wakayama Prefecture 645-0021, Japan. Electronic address: - - 2014
Influenza virus infection-induced inflammatory responses are associated with fever and other symptoms. Although macrolide antibiotics (macrolides) provide anti-inflammatory effects, these effects have not been well studied in influenza patients. We examined the effects of clarithromycin on influenza symptoms. A randomized, prospective, and open-label study was performed between December 2010 and ...
Usnarska-Zubkiewicz Lidia L Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, - - 2014
AL amyloidosis is an acquired systemic disease in which a pathologic amorphous substance produced as a result of abnormal protein metabolism is deposited in the extracellular space of various tissues. The aim of the study was to investigate the relationship between the kappa and lambda serum free light chains (sFLCs) and the ...
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