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Pareés Isabel I 1 Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, - - 2014
Functional movement disorders require attention to manifest yet patients report the abnormal movement to be out of their control. In this study we explore the phenomenon of sensory attenuation, a measure of the sense of agency for movement, in this group of patients by using a force matching task. Fourteen ...
Korkmaz Levent L aDepartment of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital bDepartment of Radiology, Akcaabat State Hospital, Trabzon, - - 2014
Detection of increased arterial stiffness could prevent patients from being mistakenly classified as being at a low or a moderate risk, when they actually are at a high risk. The main aim of present study was to investigate the relation between fragmented QRS (fQRS) on ECG and the cardio-ankle vascular ...
Matsushita Hiroshi H Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, - - 2014
Inappropriate innate immune responses have been suggested to contribute to the pathogenesis of primary sclerosing cholangitis (PSC). We evaluated the associations of expressions of toll-like receptor (TLR) 4, TLR9 and NOD-like receptor family pyrin domain containing 3 (NLRP3) in the biliary epithelial cells (BECs) with clinical features of PSC patients. ...
Schnakers Caroline C University Hospital of Liège, Liège, Belgium University of Liège, Liège, Belgium - - 2014
Background. Despite recent evidence suggesting that some severely brain-injured patients retain some capacity for top-down processing (covert cognition), the degree of sparing is unknown. Objective. Top-down attentional processing was assessed in patients in minimally conscious (MCS) and vegetative states (VS) using an active event-related potential (ERP) paradigm. Methods. A total ...
Mendoza-Pinto C C Systemic Autoimmune Diseases Research Unit, IMSS, Puebla, Mexico Department of Rheumatology and Immunology, Benemérita Universidad Autónoma de Puebla, - - 2014
Low bone mineral density (BMD) and vertebral fractures (VF) have been associated with atherosclerosis in the general population. We sought to investigate the relationship between BMD and VF and carotid atherosclerosis in women with systemic lupus erythematosus (SLE). We studied 122 women with SLE. All patients had BMD, carotid intima-media ...
Liu Yong Y Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China These authors contributed equally to this - - 2014
We determined a relatively safe contrast media volume-to-creatinine clearance (V/CrCl) cutoff value to avoid contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in patients (n = 111) with reduced ejection fraction (<40%). Improved prediction of CIN in these patients would be useful. Multivariate regression models were used to evaluate whether ...
Akyüz Aydın A Department of Cardiology, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey - - 2014
This study investigated whether there is a relationship between atrial fibrillation (AF), mean platelet volume (MPV), and apnea hypopnea index (AHI) in patients who have obstructive sleep apnea syndrome (OSAS). We enrolled patients who had OSAS with either AF or normal sinus rhythm (NSR). We divided 90 patients (aged 50-80 ...
Ceresini Graziano G Department of Clinical and Experimental Medicine, Endocrinology of Aging Unit, University of Parma, Parma, Italy. Electronic address: - - 2014
Idiopathic retroperitoneal fibrosis (IRF) is a rare disease often associated with autoimmune disorders. Whether IRF is associated with Hashimoto's thyroiditis (HT) is poorly understood and only addressed by case-reports. We evaluated the prevalence of HT in a large IRF cohort and in matched controls. We studied 73 consecutive patients with ...
Ahn J HyunBaek JH Department of Oral and Maxillofacial Surgery, Northampton General Hospital, Northampton, United - - 2014
Background The anterolateral thigh flap has gained popularity over the last few decades for the reconstruction of various surgical defects. The anatomy of the main perforating vessel of the anterolateral flap, the descending branch of the lateral circumflex femoral artery (dbLCFA), has been well described in the literature, however only one ...
Blight Andrew R AR Acorda Therapeutics, Ardsley, New - - 2014
Walking impairment is a clinical hallmark of multiple sclerosis (MS). Dalfampridine-ER, an extended-release formulation of dalfampridine (also known by its chemical name, 4-aminopyridine, and its international nonproprietary name, fampridine), was developed to maintain drug plasma levels within a narrow therapeutic window, and assessed for its ability to improve walking in ...
Dahlqvist J R JR Neuromuscular Research Unit, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, - - 2014
Patients with myotonic dystrophy type 1 (DM1) have an increased incidence of endocrine dysfunction. In this study, the temporal evolution of endocrine dysfunction in patients with DM1 was investigated. Endocrine function was assessed in 68 patients with DM1, in whom endocrine function had been followed, on average, for 8 years. The ...
Kosturakis Alyssa K AK Alyssa K. Kosturakis, Zijing He, Yan Li, Nina Shah, Sheeba K. Thomas, Haijun Zhang, Elisabeth G. Vichaya, Xin Shelley Wang, Charles S. Cleeland, and Patrick M. Dougherty, University of Texas MD Anderson Cancer Center, Houston, TX; Jessica A. Boyette-Davis, York College, York, PA; Gwen Wendelschafer-Crabb and William R. Kennedy, University of Minnesota School of Medicine; and Donald A. Simone, University of Minnesota School of Dentistry, Minneapolis, - - 2014
The goal in this study was to determine the incidence of subclinical neuropathy in treatment-naive patients with multiple myeloma (MM) with no history of peripheral neuropathy using quantitative sensory tests (QSTs) and its correlation with innervation density of the extremities using noninvasive laser reflectance confocal microscopy. QST results were collected ...
Tani N N Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Fukuoka, - - 2014
Systematic study of pemphigoid gestationis (PG) has not been performed due to rarity of PG. Clinical and immunological analyses for 25 new PG patients. In addition to clinical and histopathological assessments, we performed various immunofluorescence, immunoblotting and enzyme-linked immunosorbent assays (ELISAs). PG developed preferentially during second or third trimester of ...
Kaido T T Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, - - 2014
Severe sepsis is a life-threatening complication after liver transplantation (LT) that can be difficult to diagnose and appropriately treat after LT because of patients being treated with immunosuppressants. The present study examines perioperative changes in serum procalcitonin (PCT), a specific marker of systemic bacterial infection, and determines the value of ...
Hung Szu-Chun SC Division of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Buddhist Tzu Chi University, - - 2014
The introduction of erythropoiesis-stimulating agents (ESAs) markedly improved the lives of many anemic patients with chronic kidney disease (CKD). In Taiwan, the strategy of management of anemia in patients with CKD was different from many other parts of the world. In 1996, the National Health Insurance Administration of Taiwan applied ...
Takeuchi Naoyuki N 1Department of Physical Medicine and Rehabilitation, Tohoku University Graduates School of Medicine, Sendai, Japan 2Rehabilitation Support Center, Miyagi Prefectural Government, Natori, - - 2014
Sensorimotor rhythm (SMR) patterns in patients with lower limb amputations might be altered due to reorganization of the sensorimotor cortices. We evaluated the SMR of motor imagery (MI) in healthy subjects and patients with lower limb amputations. In addition, we investigated whether transcranial direct current stimulation (tDCS) could modulate SMR ...
El-Chammas Khalil I KI *Mercy Medical Center, Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition Des Moines, IA †Makassed Hospital, Department of Pediatrics, Division of Pediatric Pulmonology, Jerusalem, Israel ‡Boston University, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Boston, MA §Medical College of Wisconsin, Department of Pediatrics, Division of Pediatric Pulmonology, Milwaukee, WI ||Medical College of Wisconsin, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Milwaukee, - - 2014
Screening for cystic fibrosis (CF) is suggested in patients with rectal prolapse. Little is known about this association in the era of newborn screening (NBS) for CF. Our retrospective review showed that 3.6% of patients with rectal prolapse had CF, and 3.5% of CF patients had rectal prolapse. No demographic ...
Andreu-Ballester Juan C JC Research Department, Arnau de Vilanova Hospital, Valencia, Spain. Electronic address: - - 2014
We recently demonstrated an overall decrease of all αβ and specially γδ T cell subsets in patients with sepsis compared with healthy subjects. IL-7 is a crucial factor for development of γδ T cells and survival in sepsis but its association with sepsis severity, evolution of organ failure and death ...
Vreede C L CL Department of Pulmonology, Haga Teaching Hospital, Leyweg 275, 2545 CH The Hague, The - - 2014
In patients with Cystic Fibrosis and a type III mutation, ivacaftor (Kalydeco®, Vertex) can increase the opening time of the CFTR channel and improve chloride transport. Research showed significant improvement of lung function and increase in weight following ivacaftor use. However, ivacaftor showed to have adverse events on the sinonasal ...
Yamashita Takeshi T The Cardiovascular Institute, Tokyo, Japan. Electronic address: - - 2014
To maximize protection against stroke with minimal bleeding, warfarin therapy in nonvalvular atrial fibrillation (NVAF) requires tight control within a narrow therapeutic range, which might depend on racial variations. The J-RHYTHM Registry followed 6404 NVAF patients treated with warfarin for 2 years. Using international normalized ratios (INRs) at or closest ...
Huang Qing-Chun QC Department of Rheumatology, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou 510006, - - 2014
Patients with rheumatoid arthritis (RA) appear to be at a higher risk of lung cancer (LC). Although the connection between RA and LC has been an active area of research for many years, the molecular pathogenesis of the disease process remains unclear. The cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway has been shown ...
Takaya Yoichi Y Department of Cardiology, National Cerebral and Cardiovascular Center, Suita, - - 2014
Since acute kidney injury (AKI) is not always related to mortality in patients with acute decompensated heart failure (ADHF), the aim of this study was to focus on onset time of AKI and its clinical importance. A total of 371 ADHF patients were included. The impact of AKI (≥0.3 mg/dl or ...
Ardissino Gianluigi G Center for HUS Control, Prevention and Management, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122, Milan, Italy, - - 2014
Shigatoxin-associated hemolytic uremic syndrome (STEC-HUS) is a common thrombotic microangiopathy (TMA) in which central nervous system (CNS) involvement is responsible for the majority of deaths and for severe long-term sequelae. We have analyzed the role of hemoconcentration in disease severity. This was a retrospective review of the records and laboratory ...
Rolf Sascha S University of Leipzig - Heart Center, Department of Electrophysiology, Leipzig, Germany - - 2014
-Reduced electrogram amplitude has been shown to correlate with diseased myocardium. We describe a novel individualized approach for catheter ablation of atrial fibrillation (AF) based on low-voltage areas (LVAs) in the left atrium (LA). We sought to assess (a) the incidence of LVAs in patients undergoing AF catheter ablation, (b) ...
Sato Fumiya F Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-Ku, Nagoya, 466-8550, - - 2014
Left hepatic trisectionectomy is a challenging procedure. For an anatomically correct resection, it is necessary to have understanding of the right intersectional plane; however, little is known on this issue. The purpose of this study was to investigate the 3D anatomy of the right intersectional plane and to enable safe ...
Koca Bülent B Department of Paediatric Cardiology, Harran University Medical Faculty, Şanlıurfa, Turkey, - - 2014
Juvenile idiopathic arthritis (JIA) is a systemic chronic inflammatory disease. Cardiac involvement as pericarditis, myocarditis and valvular disease is common in JIA. This study aims to assess left ventricular (LV) diastolic functions with tissue Doppler imaging (TDI) and to compare it with conventional Doppler echocardiography (pulse wave Doppler (PWD)) techniques ...
Laukka Jeremy J JJ Department of Neuroscience, University of Toledo, Toledo, Ohio; Center of Molecular Medicine and Genetics, Wayne State University, Detroit, - - 2014
Pelizaeus-Merzbacher disease (PMD) is an X-linked disorder of the central nervous system (CNS) caused by a wide variety of mutations affecting proteolipid protein 1 (PLP1). We assessed the effects of PLP1 mutations on water diffusion in CNS white matter by using diffusion tensor imaging. Twelve patients with different PLP1 point ...
Pellino Gianluca G Department of Medical, Surgical, Neurologic, Metabolic and Ageing Sciences, Second University of Naples, Naples, Italy. Electronic address: - - 2014
A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate ...
Gallego-Villar Lorena L Centro de Biología Molecular "Severo Ochoa", UAM-CSIC, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), IdiPAZ, Madrid, - - 2014
Propionic acidemia (PA), caused by a deficiency of the mitochondrial biotin dependent enzyme propionyl-CoA carboxylase (PCC) is one of the most frequent organic acidurias in humans. Most PA patients present in the neonatal period with metabolic acidosis and hyperammonemia, developing different neurological symptoms, movement disorders and cardiac complications. There is ...
Sharma Ashish A Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Straße 65, Biberach 88400, Germany. Electronic address: - - 2014
Tiotropium is the first bronchodilator to be studied systematically in cystic fibrosis (CF). We investigated whether any intrinsic or extrinsic factors affected pharmacokinetic (PK) parameters of inhaled tiotropium delivered by Respimat(®) in adults and children with CF. Tiotropium PK in patients with CF was compared with that of healthy volunteers ...
Lammers Willem J WJ Dept of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The - - 2014
Non-invasive surrogate endpoints of long-term outcomes of patients with primary biliary cirrhosis (PBC) are needed to monitor disease progression and evaluate potential treatments. We performed a meta-analysis of individual patient data of cohort studies to evaluate whether patient levels of alkaline phosphatase and bilirubin correlate with their outcomes and can ...
Arce Manrique Borbón MB Department of Nuclear Medicine, Hospital Universitario Virgen Macarena, Seville, Spain. Electronic address: - - 2014
To report five cases of patients diagnosed with differentiated thyroid carcinoma (DTC) with uptake in the thymic area after high-dose treatment with I-131 and to evaluate the potential causes and therapeutic management. Five cases of young female patients with a mean age of 36.6 years (24-43) who had been treated ...
Zhang Minmin M Division of Nephrology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, P.R. - - 2014
Background: Residual kidney function (RKF) has consistently been a predictor of greater survival in maintenance hemodialysis (MHD) patients. The relationship between hemodialysis (HD) treatment frequency and RKF preservation has not been well examined. We hypothesized that initial twice-weekly HD helps in maintaining a longer RKF. Methods: In a dialysis center ...
Ohashi Ryuji R Division of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, - - 2014
Disseminated intravascular coagulation (DIC), a thrombohemorrhagic disorder, occurs as a secondary complication in many diseases, but the histopathological features of kidneys in DIC have not been extensively characterized thus far. We reviewed 21 autopsy cases of patients with a clinical diagnosis of DIC and studied the repertoire of renal pathology. ...
Acar Mehtap M From the *Dr. Sami Ulus Children Hospital; Departments of †Otorhinolaryngology and ‡Pediatrics, Kecioren Training and Research Hospital, Ankara, - - 2014
We aimed to describe the feasibility of a prediction of adenoid hypertrophy by pediatricians for diagnostic accuracy of nasopharyngeal x-ray in a pediatric unit. Forty-six patients with a history of probable adenoid hypertrophy between January 2013 and August 2013 were included in the study. Participants were excluded from the study ...
Erçin Cengiz C Department of Pathology, Faculty of Medicine, University of Kocaeli İzmit, Kocaeli, - - 2014
Cystinosis is an autosomal recessive lysosomal storage disease. We present 2 siblings in whom cystinosis was detected by CD68 immunohistochemical analysis of bone marrow biopsies. The older patient was a 6-year-old boy who had been receiving erythrocyte suspension therapy for 5.5 years because of low hemoglobin levels. The patient was ...
Breithardt Günter G Department of Cardiovascular Medicine, Division of Electrophysiology, University Hospital Münster, Von-Esmarch-Strasse 117, Münster D-48149, Germany - - 2014
We investigated clinical characteristics and outcomes of patients with significant valvular disease (SVD) in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial. ROCKET AF excluded patients with mitral stenosis or artificial ...
Estes Jaclyn L JL *Weill Cornell Medical College and †Department of Radiology, Weill Cornell Medical College, Cornell University; ‡NewYork-Presbyterian Hospital; §Department of Public Health and ‖Department of Ophthalmology, Weill Cornell Medical College, Cornell University, New York, New York, - - 2014
The purpose of this study was to determine if a significant difference exists in the nasolacrimal duct volume of subjects with primary nasolacrimal duct obstruction compared with that of controls. This was a retrospective, case-control study of 70 subjects with prior maxillofacial CT scans, including 35 subjects with obstruction and ...
Do Bao Anh BA Faculty of Medicine, McGill University, Montreal, Quebec, Canada - - 2014
Many predictive models for risk of malignancy in well-differentiated thyroid cancer (WDTC) have been proposed, and many scoring systems for thyroid cancer prognosis have been established. Age is taken in consideration in all. Our main goal is to establish whether patients' age has a correlation with the rate of malignancy, ...
Djordjevic-Jocic Jasmina J Clinic of Ophthalmology, Faculty of Medicine, University of Nis, Nis, - - 2014
The goal of this study was to examine, the relationship between chronic kidney disease (CKD) and glaucomatous optic disc neuropathy in a cohort of patients from the south-east Serbia and to determine whether limited screening for glaucoma in specific subgroups of patients with CKD is reasonable and justifiable. This cross-sectional ...
Wang Joanna Y JY Division of Pediatric Neurosurgery, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; - - 2014
Object The most common neurosurgical condition observed in preterm infants is intraventricular hemorrhage (IVH), which often results in posthemorrhagic hydrocephalus (PHH). These conditions portend an unfavorable prognosis; therefore, the potential for poor neurodevelopmental outcomes necessitates a better understanding of the comparative effectiveness of 2 temporary devices commonly used before the ...
Guo Wenbin W Mental Health Institute of the Second Xiangya Hospital, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan 410011, China; Mental Health Center, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, - - 2014
Studies have shown that patients with schizophrenia and their siblings share decreased gray matter (GM) volumes in certain brain regions, which may represent candidate endophenotypes of schizophrenia. However, the specificity and utility of these possible endophenotypes in relation to schizophrenia remain unclear. Twenty drug-naive, first-episode schizophrenia patients and 20 first-degree ...
Di Lernia V V Dermatology Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, - - 2014
Psoriasis is a highly heritable disease. It has been suggested that psoriasis is preferentially transmitted from fathers. To evaluate the degree of familial aggregation of psoriasis; to determine the recurrence risk ratio (λR ) of psoriasis in first, second and third degree relatives of patients with psoriasis; and to investigate ...
Yoon Jung Han JH Department of Neurology, Ajou University School of Medicine, Suwon, South - - 2014
Levodopa (l-dopa) therapy in Parkinson's disease (PD) increases serum homocysteine levels because of its metabolism via catechol O-methyltransferase, which may lead to endothelial dysfunction. We enrolled 40 PD patients treated with l-dopa, 33 PD patients treated with l-dopa/entacapone, 22 untreated PD and 30 controls, and compared the flow-mediated dilation in ...
Sliwińska-Mossoń Mariola M Department of biomedical and environmental analysis, Wrocław Medical University, 211 Borowska, Poland. Electronic address: - - 2014
The aim of the study was to provide knowledge on somatostatin and its action on the body, particularly the pancreas - in physiological and pathological conditions. In order to get to know the properties of somatostatin, a hormone discovered over forty years ago, many studies that define its structure and the mechanisms ...
Chen Ji-Yih JY Attending physician. Department of Medicine, Division of Allergy, Immunology and Rheumatology, Chang Gung Memorial Hospital, Chang Gung University College of - - 2014
Objective: To determine whether copy number variations (CNVs) of FCGR3A and FCGR3B genes are associated with SLE and RA in Taiwanese. Methods: CNV genotypes of FCGR3A and FCGR3B were determined in 846 SLE patients, 948 RA patients, and 1420 healthy controls with custom TaqMan CNV assays. Genotypes of FCGR3A and ...
Letanneux Alban A Aix-Marseille Université, CNRS, Laboratoire Parole et Langage, UMR 7309, Aix-en-Provence, - - 2014
Micrographia, an abnormal reduction in writing size, is a specific behavioral deficit associated with Parkinson's disease (PD). In recent years, the availability of graphic tablets has made it possible to study micrographia in unprecedented detail. Consequently, a growing number of studies show that PD patients also exhibit impaired handwriting kinematics. ...
Du T T Department of General Surgery, Zhongnan Hospital, School of Medicine, National Wuhan University, Wuhan, Hubei Province, - - 2014
Deep venous thrombosis (DVT) is a common surgical complication in cancer patients and evidence that inflammation plays a role in the occurrence of DVT is increasing. We studied a population of cancer patients with abdominal malignancies with the aim of investigating whether the levels of circulating inflammatory cytokines were associated ...
Moe Maung Maung Myat MM Oncology Department, Singleton Hospital, Swansea, - - 2014
Background: We wanted to evaluate the impact of peritoneal dialysis on trabectedin therapy in terms of side effects, response and levels in the blood and dialysate of a patient on peritoneal dialysis for end-stage renal failure caused by previous ifosfamide therapy. This has not yet been reported in the medical ...
Navaravong Leenhapong L Comprehensive Arrhythmia Research and Management (CARMA) Center, University of Utah Division of Cardiovascular Medicine, Salt Lake City, - - 2014
Chronic kidney disease (CKD) and atrial fibrillation (AF) often co-exist. We studied the association of CKD with atrial fibrosis and the effect of AF ablation on kidney function. AF Patients who had a pre- and post-ablation serum creatinine and who completed a late gadolinium enhancement cardiac MRI (LGE-MRI) prior to ...
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