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Jang Won Seok WS Won Seok Jang, Hyun Phil Shin, Joung Il Lee, Kwang Ro Joo, Jae Myung Cha, Jung Won Jeon, Jun Uk Lim, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-701, South - - 2014
To clarify the efficacy of proton pump inhibitors (PPIs) after endoscopic variceal obturation (EVO) with N-butyl-2-cyanoacrylate. A retrospective study was performed on 16 liver cirrhosis patients with gastric variceal bleeding that received EVO with injections of N-butyl-2-cyanoacrylate at a single center (Kyung Hee University Hospital at Gangdong) from January 2008 ...
De Cassan Chiara C Chiara De Cassan, Edoardo Savarino, Giorgia Hatem, Giacomo Carlo Sturniolo, Renata D'Incà, Division of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, - - 2014
To evaluate whether the effectiveness of Granulo-monocyto apheresis (GMA), a technique that consists of the extracorporeal removal of granulocytes and monocytes from the peripheral blood, might vary according to the severity of ulcerative colitis (UC) in patients with mild to moderate-severe disease UC activity. We retrospectively reviewed prospectively collected data ...
Zou Jun J Jun Zou, Yan Shen, Jian-Long Guan, Division of Immunology and Rheumatology, Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital, Research Center on Aging and Medicine, Fudan University, Shanghai 200040, - - 2014
To report the incidence, clinical features and outcomes of gastrointestinal (GI) involvement in Behcet's disease (BD). A total of 168 consecutive patients with BD were screened and upper and lower GI endoscopies were performed in 148 patients. Four hundred age- and sex-matched controls were enrolled for comparison. Fifty-two (35.1%) patients ...
Podnar Simon S Division of Neurology, Institute of Clinical Neurophysiology, University Medical Centre Ljubljana, 1525, Ljubljana, Slovenia, - - 2014
Phrenic neuropathies (PN) are an important cause of dyspnoea, orthopnoea and hypercapnic respiratory failure. However, there is no agreement on the nosology of this disorder. The aim of this cohort study was to analyze the author's and published PN patients and compare them with other immune-mediated focal neuropathies to determine ...
Mormina Enricomaria E Department of Biomedical Science and Morphological and Functional Images, University of Messina, via Consolare Valeria, 1 c/o A.O.U. Policlinico "G. Martino", 98125, Messina, - - 2014
Studies with diffusion tensor imaging (DTI) analysis have produced conflicting information about the involvement of the cerebellar hemispheres in Parkinson's disease (PD). We, thus, used a new approach for the analysis of DTI parameters in order to ascertain the involvement of the cerebellum in PD. We performed a fiber tract-based ...
Grande Michele - - 2014
The nature of the relationship between Helicobacter pylori and reflux esophagitis (RE) is not fully understood. In addition, the effect of H. pylori eradication on RE and gastroesophageal reflux disease (GERD) is unclear. This study was designed to investigate the relationship between H. pylori infection and the grade of GERD ...
Lo Chun-Yu CY Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom; NIHR Respiratory Biomedical Research Unit, Royal Brompton NHS Foundation Trust, London, United Kingdom; Department of Thoracic Medicine, Chang Gung Medical Foundation, Chang Gung University College of Medicine, Taipei, - - 2014
Patients with severe asthma are less responsive to corticosteroid therapy and show increased airway remodeling. The mesenchymal progenitors, fibrocytes, may be involved in the remodeling of asthmatic airways. We propose that fibrocytes in severe asthma are different from those in nonsevere asthma. To examine the survival, myofibroblastic differentiation, and C-C ...
Subasi Cemal F CF aDepartment of Internal Medicine, School of Medicine bInstitute of Gastroenterology cDepartment of Gastroenterology, School of Medicine, Marmara University, Istanbul, - - 2014
The presence of advanced liver fibrosis portends a poor prognosis in nonalcoholic fatty liver disease (NAFLD). We aimed to compare the diagnostic performance of five noninvasive scores [aspartate aminotransferase/platelet ratio (APRI), BARD, FIB-4, NAFLD fibrosis score (NFSA), and FibroMeter] for the assessment of advanced stages of fibrosis (F≥3) in patients ...
Czerninski Rakefet R Department of Oral Medicine, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, - - 2014
To compare the clinical characteristics of lichen planus with dysplasia (LD) cases with oral dysplasia (DYS), and LP/lichenoid reaction (LP/LR). Patients treated at the Department of Oral Medicine with a histological diagnosis were included. Patient information (age, gender, ethnicity, smoking habits and medical status) and parameters of oral manifestation (lesions' ...
Motegi Sei-Ichiro SI Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Gunma, - - 2014
Anti-RNA polymerase III antibody (RNAP) is primarily detected in diffuse cutaneous type systemic sclerosis (dcSSc) patients and strongly associated with renal crisis. Additionally, there has been increasing evidence that cancer in SSc patients is associated with RNAP. The aim of this study was to examine the demographic and clinical features ...
Loavenbruck A A Department of Neurology, Mayo Clinic, Rochester, MN, - - 2014
Gastrointestinal symptoms are common in the postural orthostatic tachycardia syndrome (POTS). However, few studies have evaluated gastrointestinal transit in POTS. Our primary objectives were to evaluate gastrointestinal emptying and the relationship with autonomic dysfunctions in POTS. We reviewed the complete medical records of all patients aged 18 years and older with ...
Smeekes Christiaan C Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands, - - 2014
Recently, concerns have arisen about metal-on-metal (MoM) total hip arthroplasty (THA). Therefore, the purpose of this cross-sectional cohort study was to describe the incidence of pain, pseudotumours, revisions and the relation between elevated metal ion levels, functional outcome and quality of life after MoM THA. In 351 patients, 377 MoM ...
Rohani Mohammad M Department of Neurology, Iran University of Medical Sciences, Tehran, - - 2014
Restless legs syndrome (RLS) is a common sleep disorder that can present secondary to medical conditions such as renal failure. This study aimed to evaluate RLS frequency and its related factors in chronic renal failure patients treated with hemodialysis. In a cross-sectional design, 163 patients with chronic renal failure were ...
Ohnishi T T Department of Dermatology, Teikyo University School of Medicine, Tokyo, - - 2014
We report three cases of verruciform xanthoma (VX) in male patients aged 82, 88 and 39 years, respectively. The clinical appearance was of a mulberry-like area consisting of small papillae, which is typical of and specific to VX, and the diagnosis were histologically confirmed in all cases. Dermoscopy revealed that each ...
Saluk J J Stritch School of Medicine, Loyola University of Chicago, Maywood, USA - - - 2014
As chronic kidney disease (CKD) and metabolic syndrome (MetS) share many of the same risk factors and similar inflammatory pathogenesis, multiple studies have suggested a correlation between CKD and MetS.. The purpose of this study is to investigate the prevalence of MetS in ESRD patients. Furthermore, investigating metabolic biomarker levels ...
Borazjani Ali A Global Innovations for Reproductive Health & Life, Cleveland, OH, USA, - - 2014
Most patients in regions where obstetric vesicovaginal fistulas (VVF) are endemic void using a squatting posture. Additionally, many patients continue to have lower urinary tract symptoms (LUTS) following fistula closure. We designed and validated a prototype platform that allows urodynamic studies to be performed in a squatting position and conducted ...
Guerin Claude C Service de Réanimation Médicale, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Université de Lyon, 103 Grande Rue de la Croix-Rousse, 69004, Lyon, France, - - 2014
The aim of the present study was to assess the rate of diffuse alveolar damage (DAD) on open lung biopsy (OLB) performed in the ICU for nonresolving ARDS. A single-center retrospective study of patients meeting the Berlin definition criteria for ARDS who had undergone OLB for nonresolving ARDS. Patients were ...
Aliberti Stefano - - 2014
To evaluate noninvasive ventilation (NIV) in diffuse interstitial lung diseases (DILD) patients with acute respiratory failure (ARF) according to baseline radiological patterns and the etiology of ARF. In a multicenter, observational, retrospective study, consecutive DILD patients undergoing NIV because of an episode of ARF were evaluated in six Italian high ...
Silverio Angelo A Heart Department, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, - - 2014
Aortic Dissection (AD) is the most common life-threatening disease involving the aorta. It is rarely associated with systemic disorders such as Autosomal Dominant Polycystic Kidney Disease (ADPKD), a genetic syndrome characterized by cystic degeneration of kidneys, possible presence of cysts in other organs and extra-renal manifestations, including cardiovascular disorders. We ...
Maras Jaswinder Singh JS Department of Research, Institute of Liver & Biliary Sciences (ILBS), New Delhi, 110070, - - 2014
Background and Aims: Acute-on-chronic liver failure (ACLF) is an ailment with high incidence of multi-organ failure (MOF) and consequent mortality. Dysregulated iron homeostasis and macrophage dysfunction are linked to increased incidence of MOF. We investigated whether a panel of circulating iron regulating proteins are associated with development of MOF and ...
Chyan Arthur - - 2014
BackgroundRadiation to the neck has long been associated with an elevated risk of hypothyroidism development. The goal of the present work is to define dosimetric predictors of hypothyroidism in oropharyngeal cancer (OPC) patients treated with intensity-modulated radiation therapy.MethodsData for 123 patients, with a median follow up of 4.6 years, were retrospectively ...
Varalta Valentina - - 2014
A reduction of hemispatial neglect due to stroke has been associated with activation of the contralesional hand in the contralesional hemispace. Robot-assisted upper limb training was found to effectively improve paretic arm function in stroke patients. To date no proof of concept of robot-assisted hemispatial neglect therapy has been reported ...
Mårtensson J J Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia - - - 2014
Labile iron appears to play a role in the pathogenesis of acute kidney injury (AKI). Neutrophil gelatinase--associated lipocalin (NGAL) and hepcidin are involved in iron metabolism and are both upregulated during renal stress. However, in patients at risk, the highest levels of urinary NGAL are associated with AKI severity but ...
Iliaz Sinem S Department of Pulmonology, Faculty of Medicine, Istanbul University, Istanbul, Turkey - - 2014
Patients with chronic obstructive pulmonary disease (COPD) who have nocturnal oxygen desaturation (NOD) can be treated with nocturnal oxygen therapy (NOT) to avoid possible morbidity and mortality. Although there is no definite data recommending NOT alone, our aim is to evaluate the relationship between desaturation during the six-minute walk test ...
Weier Katrin K Department of Neurology, University Hospital Basel, Switzerland - - 2014
In relapsing-remitting multiple sclerosis (RRMS), the cerebellum is a known predilection site for atrophy. Neuromyelitis optica (NMO) is characterized by extensive lesions in the spinal cord and optic nerve; however, cerebellar involvement has been less studied. Secondary degeneration of the spinocerebellar tract could impact the cerebellum in NMO. We aimed ...
Stojkovic Stefan S Department of Internal Medicine II, Division of Cardiology, Medical University of - - 2014
Background:The clinical value of T-wave variability (T-var) for ventricular arrhythmia (VA) risk prediction was evaluated.Methods and Results:Three 20-min Holter-ECG-based T-var measurements (I1 at baseline, I2 after 6.5±1.6 months and I3 after 13.1±2.0 months) were done in 121 patients. T-var was defined as the amplitude variability of the T-wave with the maximum of ...
Chari Ajai - - 2014
Carfilzomib is a selective proteasome inhibitor approved in the United States in 2012 for the treatment of relapsed and refractory multiple myeloma. Although cardiopulmonary and vascular events have been reported infrequently, they can be potentially serious complications, and their incidence and pathophysiology following carfilzomib treatment remain poorly characterized in a ...
Han Jiangna J 1Department of Pneumology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences , Beijing , - - 2014
Abstract Objective: The GOLD 2011 report recommends the use of symptoms, exacerbation history, and FEV1% predicted to categorise patients into groups A-D. We investigated the choice of mMRC or CAT on category assignment and characterization of the categories. Methods: Patients were prospectively recruited from tertiary hospitals in China, as part ...
Sclar David Alexander DA College of Pharmacy, Midwestern University, Glendale, AZ, USA, - - 2014
Remifentanil has a rapid onset and short duration of action, predictable pharmacokinetic/pharmacodynamic profile, and unlike fentanyl, does not accumulate with repeated or prolonged administration. This study evaluated predictors of remifentanil use in surgical patients with renal or hepatic impairment, or obesity in the United States who received remifentanil, fentanyl, or ...
Ng Khai-Jing KJ School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, - - 2014
The results of various studies attempting to assess the risks of venous thromboembolism in liver cirrhosis have been conflicting. Furthermore, while the incidence of venous thromboembolism is thought to be low in Asians, the relation between venous thromboembolism and liver cirrhosis has not been investigated in Asian countries. We investigated ...
Zhang Hongyan - - 2014
BackgroundOur objective is to investigate the genetic polymorphisms of the glutathione S-transferase M1 and T1 genes (GSTM1 and GSTT1) and evaluate oxidative damage in patients with non-small lung cancer (N-SCLC).MethodsOne hundred and ten patients with N-SCLC and 100 controls are included in this case-control study. Multiplex polymerase chain reaction (PCR) ...
Tosetto Alberto A Department of Cell Therapy and Hematology, Hemophilia and Thrombosis Center, San Bortolo Hospital, Vicenza, Italy; - - 2014
Type 2 von Willebrand disease includes a wide range of qualitative abnormalities of von Willebrand factor structure and function resulting in a variable bleeding tendency. According to the current classification, four different subtypes can be identified, each with distinctive phenotypic and therapeutic characteristics. Current available laboratory methods allow a straightforward ...
Ratto C C Department of Surgical Sciences, Catholic University, Rome, - - 2014
The long-term outcome of sacral nerve stimulation (SNS) for chronic functional constipation was assessed. Patients who received a definitive SNS implant for chronic functional constipation only (according to the Rome III criteria) and were followed up for at least three years were included in this study. Slow transit constipation (STC) ...
Muller Sven S Working Group for Surgical Technology and Training, Clinic for Visceral, General and Transplant Surgery, Tübingen University Hospital, Tübingen, - - 2014
Hyperbilirubinaemia is reported to be a positive predictor in diagnosing appendicitis and especially appendiceal perforation. We, therefore, analysed the diagnostic accuracy of serum bilirubin in anticipating appendicitis and its severity. All consecutive patients undergoing appendectomy for suspected appendicitis from May 2009 to August 2011 were analysed. Patients were classified based ...
Ortiz Erica - - 2014
Rhinosinusitis (RS) is characterized by inflammation extending from the mucosa of the nasal cavity into the paranasal sinuses. There are some aggravating features, such as immunosuppression, that can cause the nasal mucosal inflammation to linger for a long period, resulting in chronic or recurrent episodes. Such immunosuppression is the major ...
Cantillo-Negrete Jessica - - 2014
One of the difficulties for the implementation of Brain-Computer Interface (BCI) systems for motor impaired patients is the time consumed in the system design process, since patients do not have the adequate physical nor psychological conditions to complete the process. For this reason most of BCIs are designed in a ...
Burton Christopher C Centre of Academic Primary Care, University of Aberdeen, - - 2014
We examined symptom scores and physiological measurements from patients who were using a pilot COPD telemonitoring service. Of 33 patients recruited to the study, 19 were monitored for longer than 200 days. We identified three patterns of exacerbation, which we termed discrete (n = 5), rolling (n = 9) and over-ridden (n = 4). The association ...
Dohmen Pascal M PM Department of Cardiac Surgery, Heart Center Leipzig, University of Leipzig, Leipzig, Germany; Department of Cardiothoracic Surgery, University of the Free State, Bloemfontein, South Africa. Electronic address: - - 2014
The high risk of morbidity and mortality for patients on hemodialysis who are undergoing cardiac surgery is increased for those with active infective endocarditis (AIE). This retrospective observational single-center study evaluated the impact of chronic hemodialysis on the outcome of aortic valve replacement in patients with aortic AIE. Data were ...
Brenaut Emilie E Department of Dermatology, University Hospital, Brest, France; Laboratory of Neurosciences of Brest, University of Western Brittany, Brest, France. Electronic address: - - 2014
Small-fiber neuropathies (SFN) are diseases of small nerve fibers that are characterized by autonomic and sensory symptoms. We sought to evaluate sensory symptoms, especially pruritus, in patients with SFN. A questionnaire was given to patients with SFN. In all, 41 patients responded to the questionnaire (71.9% response rate). The most ...
Legrand Matthieu M Department of Anesthesiology and Critical Care and SMUR and Burn Unit, Assistance Publique-Hopitaux de Paris, AP-HP, GH St-Louis-Lariboisière, University of Paris 7 Denis Diderot, 1 rue Claude Vellefaux, 75010, Paris, France, - - 2014
Oliguria is a common symptom in critically ill patients and puts patients in a high risk category for further worsening renal function (WRF). We performed this study to explore the predictive value of biomarkers to predict WRF in oliguric intensive care unit (ICU) patients. Single-center prospective observational study. ICU patients ...
Poulikakos D D Cardiovascular Sciences Research Centre, St. George's University of London, Medical School, London, UK. - - 2014
T wave morphology (TWM) descriptors derived from Holter electrocardiograms during hemodialysis (HD) are of potential value for cardiac risk assessment in HD patients. Our knowledge on autonomic regulation of TWM descriptors is limited. The purpose of this study was to investigate the association between TWM parameters and heart rate variability ...
Ha Sung Hae - - 2014
Everolimus was recently introduced as a second-line treatment for renal cell carcinoma (RCC) and many other cancers. Several prospective studies have shown that serum creatinine levels are increased in a significant proportion of patients receiving everolimus. However, data on the occurrence of acute kidney injury (AKI) during everolimus treatment in ...
Meletti Stefano S Department of Biomedical Sciences, Metabolism, and Neurosciences; University of Modena and Reggio Emilia, - - 2014
We describe the epilepsy features and emotion recognition abilities (recognition of basic facial emotions and recognition of emotional prosody) in a patient with Urbach-Wiethe disease with bilateral amygdala calcifications. Our data, supported by ictal video-EEG recording, indicated that our patient suffered from mesial temporal lobe epilepsy. Emotion recognition abilities were ...
Frisch Christopher D CD Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, - - 2014
Fibrous dysplasia is a condition of nonmalignant osseous change and may occur in a monostotic or polyostotic pattern, the latter potentially being associated with McCune-Albright syndrome. Symptoms are highly variable and dependent upon lesion location and size. Retrospective review. Consecutive subjects with fibrous dysplasia of the temporal bone were evaluated ...
Vanhercke Daniel D Department of Internal Medicine, Ghent University, Ghent, - - 2014
Pulmonary hypertension (PHT) is a predictor of mortality and morbidity in patients with chronic heart failure (HF). However, the prevalence, determinants, and prognostic significance of PHT in elderly patients admitted with acute decompensated HF are unclear. We prospectively evaluated 401 patients aged ≥75 years (mean age 83 ± 5 years, 50% women) with acute ...
Schomer Andrew C AC Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, U.S.A; Harvard Medical School, Boston, Massa-chusetts, - - 2014
The cardiac component of risk for sudden unexpected death in epilepsy (SUDEP) and alterations in cardiac risk by vagus nerve stimulation (VNS) are not well understood. We determined changes in T-wave alternans (TWA), a proven noninvasive marker of risk for sudden cardiac death in patients with cardiovascular disease, and heart ...
Cohen Regev R The Ruth and Bruce Rappaport Faculty of Medicine Technion, Infectious Diseases Unit, Sanz Medical Center, Laniado Hospital, Netanya, Israel; Surgery Department, Sanz Medical Center, Laniado Hospital, Netanya, Israel - - 2014
This patient shows a rare phenomenon of schistosomal ova deposition on the serosal side of the small bowel without any pathology seen on the mucosal side of the small and large bowels. The patient was diagnosed accidentally during an elective cesarean section, when small nodules were seen on the small ...
Mohan Girish C GC Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Previous studies found conflicting results as to whether atopic dermatitis (AD) is increased in patients with vitiligo and alopecia areata (AA). To compare the prevalence of AD between patients with either vitiligo or AA and those without these disorders by performing a meta-analysis of observational studies. MEDLINE, EMBASE, Cochrane Library, ...
Kavanaugh Arthur A University of California San Diego, San Diego, La Jolla, California, - - 2014
There is increasing interest in discontinuing biological therapies for patients with rheumatoid arthritis (RA) achieving good clinical responses, provided patients maintain clinical benefit. We assessed patients with RA from the Corrona registry who discontinued treatment with their first tumour necrosis factor inhibitor (TNFi) while in low-disease activity (LDA) or lower ...
Matsuoka Shin S From the *Department of Radiology, St Marianna University School of Medicine, Kanagawa; †Department of Radiology, Graduate School of Medical Science, University of the Ryukyu, Okinawa; and ‡Department of Radiology, St Luke's International Hospital, Tokyo, - - 2014
The purpose of this study was to evaluate the differences in 5-year morphological changes among the patients with combined pulmonary fibrosis and emphysema (CPFE), emphysema alone, and fibrosis alone using quantitative computed tomography evaluation. This study involved 42 patients with CPFE, 45 patients with emphysema alone, and 35 patients with ...
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