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Phan Kevin H KH Department of Orthopaedic Surgery, University of California at Los Angeles, Los Angeles, CA. Electronic address: - - 2014
Degenerative spondylolisthesis is a common pathological condition which leads to lumbar instability and significant clinical symptoms. The effect of this pathology on adjacent lumbar motion segments, however, has not yet been studied. The purpose of this study was to characterize the motion characteristics of lumbar degenerative spondylolisthesis at both the ...
Ozeki Michishige - - 2014
Expression and/or excretion of fibroblast growth factor-23 (FGF23) and its co-receptor Klotho are altered in patients with end-stage renal disease. The possibility that the FGF23/alpha-Klotho system mediates the aggravated cardiovascular outcome among patients with chronic kidney disease (CKD) has been suggested. We determined whether FGF23 and alpha-Klotho concentrations are altered ...
Cattrysse Fabienne - - 2014
Obstructive sleep apnea and hypopnea syndrome (OSAHS) is a disorder that causes clinical symptoms (e.g. snoring, excessive daytime sleepiness and impaired concentration) that may increase the risk of traffic accidents, cardiovascular disease, type 2 diabetes and reduce the quality of life. A recently developed device (Somnolter(R)) detects apneas and hypopneas ...
Bosello Silvia L SL Department of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, - - 2014
To assess the long-term efficacy and safety of single and multiple courses of rituximab therapy in systemic sclerosis (SSc) patients with and without lung disease. A total of 20 SSc patients with a diffuse disease were treated with rituximab. At baseline and during follow-up the lung involvement was evaluated with ...
Gazdag A A Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, P.O.B. 19, Debrecen, 4012, Hungary, - - 2014
The aim of this study was to investigate aortic stiffness and left ventricular (LV) systolic and diastolic function in patients with differentiated thyroid cancer (DTC) on thyroxine (L-T4) therapy and after L-T4 withdrawal to assess the cardiovascular impact of long-term subclinical hyperthyroidism and short-term overt hypothyroidism. Twenty-four patients who had ...
Shochat Michael M Heart Institute, Hillel Yaffe Medical Center, P.O. Box 169, 38100, Hadera, Israel, - - 2014
The instantaneous lung impedance (ILI) is one of the methods to assess pulmonary congestion or edema (PCE) in chronic heart failure (CHF) patients. Due to usually existing PCE in CHF patients when evaluated, baseline lung impedance (BLI) is unknown. Therefore, the relation of ILI to BLI is unknown. Our aim ...
Yanaba Koichi K Department of Dermatology, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-Ku, Tokyo, 105-8641, Japan, - - 2014
Obesity is thought to be involved in the pathogenesis of psoriasis, although its impact on the therapeutic response to systemic treatments remains unclear. The aim of this study was to examine the association of body mass index (BMI) with the efficacy of ustekinumab in Japanese patients with psoriasis. Clinical data ...
Honjo Hirotaka H Department of Surgery, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, 296-8602, Japan, - - 2014
Intussusception is common in children but rare in adults. The goal of this study was to review retrospectively the symptoms, diagnosis, and treatment of intussusception in adults. From 1997 to 2013, we experienced 44 patients of intussusception in patients older than 18 years. The patients were divided into enteric, ileocolic, ileocecal, ...
Wu Chan C Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No.1 Shuaifuyuan Road, DongCheng District, Beijing 100730, - - 2014
To investigate clinical characteristics of Purtscher-like retinopathy and its clinical implications among patients with systemic lupus erythematosus (SLE). Observational case series. Methods: SETTING: Tertiary medical center. Patients with SLE who were diagnosed with Purtscher-like retinopathy between 2002 and 2013. Assessment and follow-up in the ophthalmology department. Visual acuity and funduscopic ...
Holinski Franca F Department of Otorhinolaryngology, Head and Neck Surgery, University Medicine Berlin, Berlin, - - 2014
Background: Multiple sclerosis (MS) is a chronic disease characterized by CNS lesions causing physical and cognitive impairment. Using psychophysical testing, an olfactory disorder is diagnosed in 15-38.5% of patients with MS. Olfactometry permits objective testing of the sensory nerve function. Methods: The study looked at 20 patients with MS. Clinical, ...
Farrokhi Shawn S Human Movement Research Laboratory, Departments of Physical Therapy and Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: - - 2014
Coexisting patellofemoral osteoarthritis (PFOA) is a common finding in patients with tibiofemoral osteoarthritis (TFOA). The purpose of this study was to elucidate whether severity of coexisting PFOA in patients with TFOA is correlated with altered sagittal-plane gait biomechanics and greater knee-specific impairments. One hundred and six patients with radiographic TFOA ...
Vasseur Philippe P Department of Hepato-Gastroenterology, Poitiers University Hospital, 86021 Poitiers, France; Laboratoire Inflammation Tissus Epithéliaux et Cytokines EA 4331, Pôle Biologie Santé, 86022 Poitiers, France. Electronic address: - - 2014
Pancreatic acinar cells are major targets of IL-22. Our aim is to study early plasma levels of IL-22, of pro- and anti-inflammatory cytokines in acute pancreatitis, and their association with severity or necrosis infection. Consecutive patients admitted to the Department of Hepato-Gastroenterology at Poitiers University of Medicine Hospital (France) with ...
Holt Edward W EW Department of Transplantation, Division of Hepatology, California Pacific Medical Center, San Francisco, CA. Electronic address: - - 2014
Oxidative stress is increased in patients with metabolic syndrome (MS). Antioxidants, including carotenoids, are decreased in MS. We hypothesized that a low skin carotenoid score (SCS), calculated using resonance Raman spectroscopy, would correlate with the presence of MS. We retrospectively reviewed consecutive patients referred for dietary assessment between 2010 and ...
Pesenti-Rossi D D Service de cardiologie, hôpital André-Mignot, Versailles hospital, 177, rue de Versailles, 78150 Le Chesnay, France; Department of cardiology, Ambroise-Paré clinic, 92200 Neuilly-sur-Seine, France. Electronic address: - - 2014
The purpose of the study was to assess whether a strategy based on a MDCT performed routinely before CA can reduce the radiation dose during the CA, without increased global exposure in patients who need imaging of CABG. A total of 147 consecutive patients were included. The radiation dose during ...
Yu Tao T Department of Critical Care Medicine, Nanjing Zhong-Da Hospital, Southeast University School of Medicine, Nanjing, - - 2014
Predicting fluid responsiveness is crucial for fluid administration in septic shock patients. Midazolam and propofol decrease vascular tone and venous return, which may influence preload dependency. However, little is known about the effects of these two sedatives on preload dependency in septic shock patients. We evaluated the effects of sedation ...
Westeneng Henk-Jan HJ Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The - - 2014
The aim of this study was to assess the involvement of deep gray matter, hippocampal subfields, and ventricular changes in patients with amyotrophic lateral sclerosis (ALS). A total of 112 ALS patients and 60 healthy subjects participated. High-resolution T1-weighted images were acquired using a 3T MRI scanner. Thirty-nine patients underwent ...
Allaix Marco E ME Center for Esophageal Diseases and Department of Surgery, Pritzker School of Medicine, University of Chicago, 5841 S. Maryland Ave, MC 5031, Chicago, IL, 60637, USA, - - 2014
Esophageal epiphrenic diverticulum (ED) is usually secondary to a primary esophageal motility disorder, such as achalasia. Whereas the recommended surgical treatment includes esophageal myotomy and diverticulectomy, the outcome of patients in whom a myotomy without ED resection is performed is not known. The purpose of this study was to compare ...
Vanmassenhove J J Renal Division, Nephrology Section, 0K12, Ghent University Hospital, De Pintelaan 185, B9000, Ghent, Belgium, - - 2014
The pathophysiology of septic acute kidney injury (AKI) is incompletely understood, and there is controversy on the role of renal hypoperfusion in early sepsis. We hypothesized that renal hypoperfusion plays a role in early sepsis and that there is a continuum between transient AKI without tubular damage, transient AKI with ...
Zhao Jinxia J Department of Rheumatology & Immunology, Peking University Third Hospital, Beijing, 100191, China. - - 2014
To develop classification criteria for early rheumatoid arthritis (ERA) based on a large cohort of early inflammatory arthritis patients and to evaluate the performance of these criteria. The study population comprised a cohort of early inflammatory arthritis patients with symptom duration less than one year. Classification criteria of ERA were ...
Muratore Francesco F Division of Rheumatology, Department of Medicine, Arcispedale S. Maria Nuova IRCCS, Reggio Emilia, Italy, Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, Division of Rheumatology, Department of Medicine, Division of Biostatistics, Department of Health Sciences Research and Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, - - 2014
The aim of this study was to compare baseline variables, treatment and outcomes in patients with large-vessel GCA (LV-GCA), primarily of the upper extremities, with those with cranial disease (C-GCA). All patients >50 years of age with radiographic evidence of subclavian LV-GCA diagnosed between 1 January 1999 and 31 December ...
Venskutonyte Laura L Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden - - 2014
Left ventricular diastolic dysfunction (LVDD) is considered to be common in patients with type 2 diabetes mellitus (T2DM), but information on its progression over time is lacking. We studied the longitudinal development of left ventricular diastolic function (LVDF) and myocardial blood flow reserve in patients with T2DM who were free ...
Gemel Joanna J Department of Pediatrics, University of Chicago, Chicago, IL, - - 2014
Normal atrial conduction requires similar abundances and homogeneous/overlapping distributions of two connexins (Cx40 and Cx43). The remodeling of myocyte connections and altered electrical conduction associated with atrial fibrillation (AF) likely involves perturbations of these connexins. We conducted a comprehensive series of experiments to examine the abundances and distributions of Cx40 ...
Bettini Luca L Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, - - 2014
Although long-term video-EEG monitoring (LVEM) is routinely used to investigate paroxysmal events, short-term video-EEG monitoring (SVEM) lasting <24h is increasingly recognized as a cost-effective tool. Since, however, relatively few studies addressed the yield of SVEM among different diagnostic groups, we undertook the present study to investigate this aspect. We retrospectively ...
Okanishi Tohru T Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, - - 2014
Multiple tubers in patients with tuberous sclerosis complex (TSC) often are responsible for drug-resistant epilepsy. The complexity of the epileptic network formed by multiple tubers complicates localization of the epileptogenic zone that is needed to design a surgical treatment strategy. High frequency oscillations (HFOs) on intracranial video-electroencephalography (IVEEG) may be ...
Lee Jun Ho JH Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hallym University, Seoul, Republic of - - 2014
This clinical study was performed to analyze the characteristics of attic cholesteatoma occurring behind a tiny retraction of the pars flaccida, which was classified as Tos type I or II and had an intact pars tensa of the tympanic membrane. The clinical records of patients who underwent tympanomastoidectomy for attic ...
Akıl Eşref E Department of Neurology, Dicle University, Diyarbakir, Turkey. Electronic address: - - 2014
The role of epicardial fat thickness (EFT) in ischemic stroke (IS) has not been previously investigated. The aim of the present study was to evaluate EFT and neutrophil/lymphocyte ratio (NLR) among patients with IS and to examine the relationship between these inflammatory markers and the incidence of IS. The cross-sectional ...
Sasaki Aya A Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, Japan; Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, - - 2014
The epithelial ovarian carcinoma (EOC) is an aggressive malignant tumor, and is currently the leading cause of gynecologic cancer death. CA125 is the most commonly used serum marker for EOC, but shows a high-false positive rate for several benign diseases such as endometriosis. The purpose of this study is therefore ...
Ermakov Simon S School of Medicine, University of California - San Francisco, San Francisco, - - 2014
A recent study using an anti-plakoglobin antibody and immunofluorescence methods in endomyocardial tissue specimens found that a marked reduction in plakoglobin staining was highly sensitive and specific for the diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC). The purpose of our study was to determine the diagnostic utility of plakoglobin immunolocalization ...
Ali Anah J AJ Division of Emergency Medicine, Washington University School of Medicine, St. Louis, - - 2014
We determine the frequency and severity of abnormal laboratory measures of coagulation after suspected or known copperhead (Agkistrodon contortrix) envenomation. We identified the charts of venomous snakebites in children presenting to St. Louis Children's Hospital over a period of time greater than 14 years and of all venomous snakebites in ...
Naimo Phillip S PS Royal Children's Hospital, Melbourne, Australia; University of Melbourne, Melbourne, - - 2014
The purpose of this study was to assess the outcomes of children undergoing repair of aortopulmonary window (APW). We conducted a retrospective review of all children (n = 43) who underwent surgical repair of APW between 1980 and 2013. Median age at surgery was 40 days (range, 13 to 125). Simple APW was ...
Yuan Ping P M.S. Department of Neurology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, China. Electronic address: - - 2014
Background: The severity of spinal muscular atrophy (SMA) is highly variable and children with heterogeneous clinical features can be classified into three phenotypes (type I-III) on the basis of age of onset and maximum motor function achieved. The aim of this study was to compare the clinical characteristics of three ...
Goldberg Ivan Am IA Discipline of Ophthalmology, University of Sydney, Sydney, Australia; Glaucoma Unit, Sydney Eye Hospital, Sydney, Australia; Eye Associates, Sydney, - - 2014
Ocular surface disease (OSD) is relatively common in glaucoma patients. OSD symptoms could be linked to prolonged exposure to preservatives in anti-glaucoma medications, especially benzalkonium chloride (BAK). The OBSERVE clinical audit was designed to track the impact of intraocular pressure lowering medications in patients with evidence of OSD to test ...
Fruchter Oren O From the Pulmonary Institute (Drs. Fruchter, Rosengarten, Kramer), Internal Medicine ( Dr. Goldberg) and the Department of Medical Laboratory ,(Dr. Ben-Zvi and Tor), Rabin Medical Center, Petah Tiqwa, Israel, and The Sackler School of Medicine , Tel-Aviv University, Tel Aviv, - - 2014
Stable COPD patients often have lower airway bacterial colonization (ABC) which may be modulate exacerbation frequency. Data regarding the association between ABC and post-procedural COPD exacerbations following bronchoscopic lung volume reduction (BLVR) is scant. Our aim was to explore the correlation between ABC, serum C-reactive protein level and the risk ...
Mehta Manish M Knight Cardiovascular Institute, Oregon Health & Science University, Portland, - - 2014
The purpose of this study was to test the hypothesis that handheld ultrasound (HHU) provides a more accurate diagnosis than physical examination in patients with suspected cardiovascular abnormalities and that its use thus reduces additional testing and overall costs. Despite the limitations of physical examination and the demonstrated superiority of HHU ...
Charbonneau Hélène - - 2014
IntroductionEchocardiographic indices based on respiratory variations of superior and inferior vena cava diameters (¿SVC and ¿IVC, respectively) have been proposed as predictors of fluid responsiveness in mechanically ventilated patients but they have never been compared simultaneously in the same patient sample. The aim of this study was to compare the ...
Moiseyenko Vladimir M VM City Cancer Center, 197758, St.Petersburg, - - 2014
Ovarian carcinomas (OC) arising in BRCA1 and BRCA2 mutation carriers demonstrate pronounced sensitivity to platinum-based therapy due to deficiency of double-strand break DNA repair. However, the choice of subsequent treatment lines for this category of women remains complicated. We considered mitomycin C for heavily pretreated hereditary OC patients, based on ...
Nasr Nathalie N Department of Clinical Neurosciences, University of Cambridge, School of Clinical - - 2014
Background:The relative stability of cerebral blood flow is maintained by the baroreflex and cerebral autoregulation (CA). We assessed the relationship between baroreflex sensitivity (BRS) and CA in patients with atherosclerotic carotid stenosis or occlusion.Methods and Results:Patients referred for assessment of atherosclerotic unilateral >50% carotid stenosis or occlusion were included. Ten healthy volunteers ...
Cherif Honar H Department of Haematology, Uppsala University Hospital , Uppsala , - - 2014
Abstract Background. Patients with hereditary haemorrhagic telangiectasia (HHT) suffer from recurrent epistaxis and bleeding from gastrointestinal telangiectasias that occur despite otherwise normal haemostasis and result in iron deficiency anaemia with increasing severity. In advanced disease, anaemia may be severe, be irresponsive to iron supplementation, and may lead to red blood ...
Kalbhenn Johannes J Department of Anaesthesiology and Critical Care Medicine, Freiburg University Medical - - 2014
Aims: Acquired Von Willebrand syndrome (AVWS) is an acquired bleeding disorder that has been reported to aggravate bleeding complications in patients with ventricular assist devices or aortic stenosis. AVWS is characterized by the loss of the high-molecular-weight (HMW) multimers of Von Willebrand factor (VWF) with consequent impaired VWF binding to ...
Esnault Pierre P Unité de réanimation de chirurgie cardiaque, service d'anesthésie réanimation 2, CHU La Timone adultes, Marseille, France, - - 2014
Takotsubo cardiomyopathy is characterized by the sudden onset of reversible left ventricular dysfunction. Associated refractory cardiogenic shock is a rare occurrence and may require extracorporeal membrane oxygenation (ECMO). We report a case of a patient who, following the inadvertent injection of 1 mg of epinephrine, presented with reverse Takotsubo cardiomyopathy ...
Picca Stefano S Nephrology and Dialysis Unit, Department of Nephrology-Urology, "Bambino Gesù" Children's Hospital-IRCCS, Rome, Italy, - - 2014
In severe neonatal hyperammonemia, extracorporeal dialysis (ECD) provides higher ammonium clearance than peritoneal dialysis (PD). However, there are limited outcome data in relation to dialysis modality. Data from infants with hyperammonemia secondary to inborn errors of metabolism (IEM) treated with dialysis were collected in six Italian centers and retrospectively analyzed. ...
Drago Francesco F DISSAL, Department of Dermatology, IRCCS A.O.U. San Martino-IST, Genoa, - - 2014
A 33-year-old man presented with a two-week history of an asymptomatic ulcer of the oropharynx and submandibular lymph nodes swelling. Laboratory examinations resulted normal, but serological tests revealed positivity for rapid plasma reagin, Treponema pallidum haemagglutination assay and anti-T. pallidum IgM antibodies. Since the patient denied any homosexual relationship, a ...
Yassin Haytham H Pediatric Cardiology Department, Hamad Medical Corporation, Doha, Qatar - - 2014
To determine whether patients with single-ventricle physiology who are free from known risk factors could skip routine pre-Fontan hemodynamic evaluation, without affecting the postoperative outcome. A diagnostic algorithm including echocardiographic, clinical, and angiographic risk factors was used retrospectively to evaluate all 44 patients who underwent Fontan completion at Hamad General ...
Rendina Domenico D Department of Medicine and Surgery, Federico II University, Naples, - - 2014
Patients with Paget's bone disease (PDB) have an increased risk of developing giant cell tumor (GCT). This study was performed to evaluate the clinical characteristics and evolution of GCT complicating PDB and to compare these clinical characteristics to those observed in two large PDB cohorts, the PDB Italian Registry and ...
Adelsberger Rolf - - 2014
Objective: Benign paroxysmal positional vertigo (BPPV) is the most common cause of dizziness. The underlying pathomechanism responsible for the recurrent vertigo attacks has been elucidated in detail, and highly effective treatment strategies (liberation maneuvers) have been developed. However, many BPPV patients complain about problems of balance especially following liberation maneuvers. ...
Nakagawa Naoki N Division of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, - - 2014
Metabolic syndrome confers an increased risk of cardiovascular disease (CVD) in the general population. The relationship between adiponectins, and clinical outcomes in patients undergoing hemodialysis remains controversial. We investigated whether adiponectins, biomarkers of inflammation, nutrition status and clinical features predict the mortality of patients undergoing hemodialysis for 6 years. We ...
Saibene Alberto Maria AM Unit of Otolaryngology, Department of Health Sciences, San Paolo Hospital, University of Milan, Milan, - - 2014
Odontogenic sinusitis and "sinonasal complications of dental disease or dental treatment" (SCDDT) have been assumed to be limited to the maxillary sinus. Nevertheless, many patients also show more extensive sinonasal involvement and, occasionally, also have associated bilateral disease. We evaluated the incidence of extramaxillary extension over an 11-year period in ...
Mansi Marta M Deparment of Biomedical and Clinical Science "Luigi Sacco", Università degli Studi di Milano, Ospedale Luigi Sacco, Milan, - - 2014
The first classification of angioedema without wheals was recently reported, and comprises different forms of the disease distinguished by aetiology, mediator of oedema and inheritance. In total, 1725 consecutive patients with angioedema without wheals were examined at our centre between 1993 and 2012. We excluded from the analysis 667 patients ...
Papatheodoridis George V GV Academic Department of Gastroenterology, Laiko General Hospital; 2nd Department of Internal Medicine, Athens University Medical School, Athens. Electronic address: - - 2014
The risk of hepatocellular carcinoma (HCC) in Caucasian patients with chronic hepatitis B (CHB) treated with entecavir (ETV) or tenofovir (TDF) is unclear. We evaluated the incidence and predictors of HCC and the accuracy of existing HCC risk scores in Caucasian CHB patients receiving ETV/TDF. This large, multicenter, retrospective cohort ...
Tükel Raşit R Department of Psychiatry, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey. Electronic address: - - 2014
Neuroimaging studies have suggested that dysfunction of the cortico-striatal-thalamo-cortical (CSTC) circuit is a key pathophysiologic feature of obsessive-compulsive disorder (OCD). Several studies using proton magnetic resonance spectroscopy ((1)H MRS) have found abnormal neural metabolite concentrations among OCD patients. The aim of this study was to investigate the metabolic integrity of ...
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