Search Results
Results 551 - 600 of 2328
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Fellinger C C FAZ - Floridsdorf Allergy Centre, Vienna, - - 2014
The clinical relevance of elevated basal serum tryptase (eBST≥11.4ng/ml) often remains unclear. BST was assessed in 15,298 patients attending our outpatient clinic. Frequency and severity of anaphylaxis was compared in 900 patients with eBST and 900 patients with normal BST. The prevalence of eBST was evaluated in patients with drug ...
Kawate Hisaya H Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, - - 2014
Subclinical Cushing's syndrome (SCS) is characterized by subtle autonomous cortisol secretion from adrenal tumors without specific signs and symptoms of hypercortisolism. Patients with SCS have a high prevalence of "lifestyle-related diseases," such as hypertension, diabetes mellitus, dyslipidemia, and osteoporosis. Long-term follow-up of SCS patients is reportedly indispensable for establishing indications ...
Panorchan Kwanpeemai - - 2014
Cancer antigen 125 (CA125) is made by peritoneal mesothelial cells and can be measured in spent dialysate effluent from peritoneal dialysis (PD) patients. It has been suggested that CA125 is a marker of peritoneal mesothelial cell mass and turnover. As PD CA125 increases during peritoneal inflammation, we wished to determine ...
Sato Hiroe - - 2014
Multiple sclerosis is a relatively rare disease, and complications of multiple sclerosis and rheumatoid arthritis are much rarer. Since anti-tumor necrosis factor therapy increases exacerbations of multiple sclerosis, complications of demyelinating diseases contraindicate anti-tumor necrosis factor therapy. There have been few reports of anti-interleukin-6 receptor therapy for patients with rheumatoid ...
Dogan Mutlu M Department of Medical Oncology, Ankara Numune Training and Research Hospital, 06100, Altindag, Ankara, Turkey, - - 2014
Malignant mesothelioma (MM) is a neoplasm which originates from serous membranes. It is relatively more common in Turkey. Ninety-nine patients between 2002-2009 were evaluated for survival and patient characteristics with chest pain, dyspnea, weight loss, loss of appetite, anemia, leukocytosis, thrombocytosis and lactate dehydrogenase (LDH) elevation, retrospectively. Male/female ratio was ...
Tsuboi Hiroto H Department of Internal Medicine, Faculty of Medicine, University of Tsukuba , Tsukuba, Ibaraki Prefecture , - - 2014
Objective. To assess the efficacy and safety of abatacept for secondary Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA). Methods. The primary endpoint of this 1-year, open-labeled, prospective, observational multicenter study of RA-associated secondary SS was the rate of SDAI remission at 52 weeks after initiation of abatacept therapy. The ...
Suda Goki G Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Hokkaido, - - 2014
Telaprevir-based therapy for chronic hepatitis C patients is effective; however, the high prevalence of dermatological reactions is an outstanding issue. The mechanism and characteristics of such adverse reactions are unclear; moreover, predictive factors remain unknown. Granulysin was recently reported to be upregulated in the blisters of patients with Stevens-Johnson syndrome ...
Ruggieri Martino M Department of Educational Sciences, Chair of Paediatrics, University of Catania, Italy; Centre for Neurocutaneous Disorders, Department of Neurosciences, University of Catania, - - 2014
Spinal neurofibromatosis [SNF] is a related form of neurofibromatosis 1 [NF1], characterised by bilateral neurofibromas (histologically proven) of all spinal roots (and, eventually, of all the major peripheral nerve branches) with or without other manifestations of classical NF1. By rigorous application of these criteria to the 98 "SNF" cases published, ...
Okamoto Takayuki T Department of Nephrology, Oji Hospital , Tokyo , Japan - - 2014
Abstract Background: Intra-abdominal free air is found frequently in patients undergoing peritoneal dialysis (PD). Some studies have investigated an association between intra-abdominal free air and peritonitis in PD patients. However, most used chest X-rays, which are of limited sensitivity, and the association was not made clear. We conducted a retrospective ...
Müller Thomas T Department of Neurology, St. Joseph Hospital Berlin-Weissensee, Gartenstr. 1, 13088, Berlin, Germany, - - 2014
Repeated intrathecal application of the sustained release steroid triamcinolone acetonide is beneficial in progressive multiple sclerosis patients. Its putative regenerative effect may involve regulation of the repulsive guidance molecule A synthesis. This protein inhibits axonal regeneration and functional recovery. Objectives were to demonstrate the efficacy of four triamcinolone applications every ...
Rosario Pedro W PW Postgraduate Program and Endocrinology Service, Instituto de Ensino e Pesquisa da Santa Casa de Belo Horizonte, Rua Domingos Vieira, 590, Santa Efigênia, Belo Horizonte, MG, 30150-240, Brazil, - - 2014
We evaluated the negative predictive value (NPV) of thyroglobulin obtained 24 h after the second recombinant human TSH (rhTSH) ampoule (Tg-D3), before ablation with (131)I, for persistent/recurrent disease (PRD) in low/intermediate risk patients with papillary thyroid carcinoma. One hundred and one patients with Tg-D3 ≤1 ng/ml without anti-Tg antibodies (TgAb) were selected. ...
Pitoia Fabián F División Endocrinología, Hospital de Clínicas, University of Buenos Aires, Córdoba 2351, 5th Floor, Buenos Aires, Argentina, - - 2014
The objective of this study was to evaluate the initial response to treatment and the long-term outcome of patients with papillary thyroid cancer (PTC), according to the modified 2014 risk of recurrence classification of the American Thyroid Association and the presence or absence of insulin resistance (IR). We retrospectively reviewed our ...
Kurtulmus Neslihan N Division of Internal Medicine, Department of Endocrinology, Faculty of Medicine, Acibadem University, Buyukdere Cad. No: 40, Maslak-Istanbul, Turkey, - - 2014
Langerhans cell histiocytosis (LCH) is a rare disease in which the most common endocrine manifestation is diabetes insipidus (DI). Data on anterior pituitary function in patients with LCH are limited. Thus, the present study investigated anterior pituitary function in LCH patients with DI via the evaluation of clinical and radiological ...
Piccione Ezequiel A EA Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, USA, - - 2014
Objective: To characterize autonomic impairment in motor neuron disease. Methods: Neurological evaluations and autonomic testing were analyzed retrospectively in 132 patients: 86 classic amyotrophic lateral sclerosis (ALS), 36 lower motor neuron disease (LMN), and 10 upper motor neuron predominant (UMN). Results: One-third of patients were symptomatic; urinary urgency and constipation ...
de Carvalho Fabricio Leite FL Division of Urology, University of Sao Paulo School of Medicine, Sao Paulo, - - 2014
We assessed the lower urinary tract symptoms (LUTS) and urodynamic findings in patients with neuromyelitis optica spectrum disorders (NMO-SD), a recently defined neurological disease. We prospectively evaluated seven men and 23 women (mean age 41.1 ± 13.5 years) with an established diagnosis of NMO-SD who were invited to participate irrespective of the ...
Orlacchio Antonio A Department of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital Tor Vergata, Rome, Italy; Organ Transplantation Unit, University Hospital Tor Vergata, Rome, Italy. Electronic address: - - 2014
The aim of this study is to evaluate the usefulness of real-time elastography (RTE) in the diagnosis of graft interstitial fibrosis. We prospectively enrolled 50 patients clinically suspected of graft fibrosis. RTE was performed with a broadband linear transducer using a dedicated ultrasound machine. Tissue mean elasticity (TME) was calculated ...
Spektor Michael M Yale University School of Medicine, Department of Diagnostic Radiology, - - 2014
To describe laboratory and imaging findings associated with mortality in patients with gastric pneumatosis. Institution review board approval was obtained for this retrospective study. Using radiology report databases, all patients with "gastric pneumatosis" or "emphysematous gastritis" in their CT reports were identified from two institutions during 12 or 9 year ...
Chang Pei-Yeh PY Division of Pediatric Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan. Electronic address: - - 2014
We determined the chest height in a cohort of patients with primary spontaneous pneumothorax (PSP) who had received chest radiographic examinations prior to the attack. The aim of this study was to determine when their chest height began to change and how this was related to the PSP. From June ...
Fargo John H JH Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Md., - - 2014
Fanconi anemia (FA) is a rare inherited bone marrow failure syndrome (IBMFS). Affected individuals must be distinguished from relatives, patients with mosaicism must be identified, and patients with other IBMFS classified as non-FA. The diagnostic feature of FA is increased chromosomal breakage in blood lymphocytes cultured with diepoxybutane or mitomycin ...
Alroughani Raed R Division of Neurology, Department of Medicine, Amiri Hospital, Kuwait, - - 2014
Using the MS registries in two MS clinics in Kuwait, we studied the demographics and clinical characteristics of multiple sclerosis (MS). Data of 736 patients (77.7% with relapsing remitting course) were analyzed. The mean age at onset and mean duration were 26.87 and 7.71 years, respectively. About 47.9% of patients ...
Pamuk Omer Nuri ON Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, - - 2014
Genetic polymorphisms of platelet endothelial cell adhesion molecule-1 (PECAM-1) were found to play roles in atherosclerotic events. We determined PECAM-1 polymorphisms, soluble PECAM-1, and CD40L levels in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and evaluated their associations with clinical atherosclerotic complications. We included 100 RA patients, 81 SLE ...
Machaczka Maciej M Medical Faculty, University of Rzeszow, 35-959, Rzeszow, Poland, - - 2014
A viral contamination of the production plant producing imiglucerase (Cerezyme™) resulted in an unpredicted worldwide shortage of global supplies during 2009-2010. The aim of the study was to describe the effects of dose reduction of enzyme replacement therapy (ERT) in adults with Norrbottnian form of Gaucher disease type 3 (N-GD3). ...
Pinto Susana S Institute of Physiology and Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon , Lisbon , - - 2014
Clinical assessment of the respiratory function is critical in amyotrophic lateral sclerosis (ALS). A standardized process is to monitor the respiratory subscore of the revised ALSFRS (RofALSFRS-R). We tested the utility of RofALSFRS-R and its individual questions in evaluating respiratory functionality. Three hundred and fifty-seven consecutive ALS patients were assessed ...
Chan WengOnn W South Australian Institute of Ophthalmology and Discipline of Ophthalmology & Visual Sciences, University of Adelaide , Adelaide , Australia - - 2014
Abstract Purpose: The role of assisted local anaesthetic (aLA) for both endoscopic and external dacryocystorhinostomy is a well-tolerated and established approach. However the tolerability of aLA is unclear with powered burrs used in powered endoscopic DCR (PEDCR). We aim to evaluate the acceptability of aLA for PEDCR. Methods: This is ...
Koulaouzidis Anastasios A Centre for Liver and Digestive Disorders, Royal Infirmary of Edinburgh, Scotland, United - - 2014
Esophageal capsule endoscopy (ECE) is considered to be an alternative to conventional esophagogastroduodenoscopy (EGD); however, its indications continue to expand. This report presents results from the use of ECE in patients with hemophilia at a tertiary referral academic center over a 7-year period. A total of 16 patients with hemophilia, ...
Lim Mi-Kyoung MK Division of Rheumatology, Department of Internal Medicine, Eulji University School of Medicine, 95 Dunsanseo-ro, Seo-gu, Daejeon, 302-799, South - - 2014
The aim of this study was to determine whether peptidyl arginine deiminase (PADI) genes could affect susceptibility to tuberculosis (TB), which can be a presumptive base to explain the increased incidence of TB in patients with rheumatoid arthritis (RA) in Korean. The study population consisted of 47 patients with active ...
Sadowski Krzysztof K Department of Neurology, Health Science Faculty, Warsaw Medical University, Kondratowicza 8, 03-242, Warsaw, Poland, - - 2014
Accumulating data confirm the usefulness of transcranial sonography (TCS) in the diagnosis of Parkinson's disease. The relevance of basal ganglia abnormalities depicted by TCS in atypical parkinsonian syndromes still needs further assessment. In the present study, 20 patients with progressive supranuclear palsy (PSP) and 13 patients with corticobasal syndrome (CBS) ...
Ehler Eric D ED Department of Radiation Oncology, University of Minnesota, MMC494, 420 Delaware Street SE, Minneapolis, MN 55455, - - 2014
The purpose of this study was to test the feasibility of a patient specific phantom for patient specific dosimetric verification.Using the head and neck region of an anthropomorphic phantom as a substitute for an actual patient, a soft-tissue equivalent model was constructed with the use of a 3D printer. Calculated ...
Pan Shan S School of Pharmacy, University of Otago, Dunedin, New - - 2014
Therapeutic drug monitoring in patients with rheumatoid arthritis (RA) receiving methotrexate (MTX, MTXGlu1) has not been established. In this study, we aim to explore the relationship between red blood cell (RBC) concentrations of MTX and its polyglutamate metabolites (MTXGlu n ; n = 2, 3, 4, 5) and clinical response in RA ...
Hall Andrew M AM Institute of Anatomy, University of Zurich, Zurich, - - 2014
We studied the extent and nature of renal involvement in a cohort of 117 adult patients with mitochondrial disease, by measuring urinary retinol-binding protein (RBP) and albumin; established markers of tubular and glomerular dysfunction, respectively. Seventy-five patients had the m.3243A>G mutation and the most frequent phenotypes within the entire cohort ...
Proft F F Division of Rheumatology and Clinical Immunology, Medical Clinic and Polyclinic IV, Ludwig-Maximilians-University Munich , Erlangen , - - 2014
Objectives: Recent findings suggest that autoimmune disorders predispose to a diminished capacity to taste and smell. This has been shown for patients with systemic lupus erythematosus as well as for patients with rheumatoid arthritis (RA). Granulomatosis with polyangiitis (GPA), with its particular manifestations in the upper respiratory tract, may therefore ...
Steinberg Benjamin A BA Duke Clinical Research Institute, PO Box 17969, NC 27715 Durham, NC, USA - - 2014
Anticoagulation prophylaxis for stroke is recommended for at-risk patients with either persistent or paroxysmal atrial fibrillation (AF). We compared outcomes in patients with persistent vs. paroxysmal AF receiving oral anticoagulation. Patients randomized in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of ...
Misra U K UK Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, Uttar Pradesh, - - 2014
To evaluate the neurological manifestations of scrub typhus and correlate their clinical, EEG and MRI findings. A cross-sectional study over 2 years included patients with scrub typhus diagnosed by solid phase immunochromatographic assay or Weil-Felix test. A detailed clinical evaluation including Glasgow Coma Scale (GCS) was documented. Blood counts, chemistry, ECG, ...
Scirica Benjamin M BM TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA - - 2014
To determine the effect of ranolazine, an anti-ischaemic agent with anti-arrhythmic properties, on the overall burden of atrial fibrillation (AF) in acute coronary syndromes (ACS) and determine whether ranolazine reduces the long-term incidence of clinical AF after ACS. MERLIN-TIMI 36 randomized patients with non-ST elevation ACS to ranolazine or placebo. ...
Lund C C National Center for Epilepsy, Oslo University Hospital, Oslo, Norway; Department of Neurology, Vestfold County Hospital, Tønsberg, - - 2014
The prevalence of multiple sclerosis (MS) is increasing worldwide. Epileptic seizures are more common in MS patients than in the general population. The aim of this study was to investigate changes in the prevalence and incidence of MS in a well-defined population over several decades and estimate the occurrence of ...
Attivi David D CHOV, Site de Neufchâteau, Pharmacie, 1280, Avenue de la Division Leclerc, 88300, Neufchâteau, - - 2014
Background Patients with advanced cancers are at high risk for bone metastases, which accelerate bone resorption and skeletal complications. Therefore, bisphosphonates, which are strong inhibitors of bone resorption, are widely used to prevent pathological fractures, pain and tumour-induced hypercalcaemia. Intravenous infusion of bisphosphonate is associated with dose- and infusion rate-dependent ...
Senel Engin E Department of Dermatology, Hitit University Faculy of Medicine, Çankırı State Hospital, Çankırı, - - 2014
Tularemia is a serious and potentially life-threatening zoonosis caused by Francisella tularensis, a highly infective, gram-negative coccobacillus. Although there are plenty of case reports and studies of tularemia outbreaks, the literature is lacking in reports on dermatologic manifestations of the disease. This study aimed to identify skin manifestations in clinical ...
Haanstra Jasmijn F JF Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The - - 2014
The aim was to determine the prevalence of small-bowel neoplasia in asymptomatic patients with Lynch syndrome (LS) by video capsule endoscopy (VCE). After obtaining informed consent, asymptomatic proven gene mutation carriers aged 35-70 years were included in this prospective multicentre study in the Netherlands. Patients with previous small-bowel surgery were excluded. ...
Zhao Liang-Ping LP aDepartment of Cardiology, The First Affiliated Hospital of Soochow University bDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou City, China cDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore dDepartment of Mathematics & Statistics, Faculty of Engineering, Technology & Science, La Trobe University, Melbourne, Victoria, - - 2014
Previous studies have reported that insulin resistance is related to early in-stent restenosis (ISR) after coronary stenting. This study aimed to evaluate the influence of insulin resistance on the long-term angiographic outcome in patients undergoing coronary drug-eluting stent (DES) implantation. Within a single hospital-based cohort of patients (n=529) who underwent ...
Zhang Changming C National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, - - 2014
MicroRNAs (miRNAs) are stable in circulation, and their unique expression profiles can serve as fingerprints for various diseases. This study explored whether plasma miRNAs could be used as biomarkers to evaluate disease activity in patients with focal segmental glomerulosclerosis (FSGS). Retrospective and prospective cohorts. 78 patients with FSGS with nephrotic ...
Tsuruya Kazuhiko K Department of Integrated Therapy for Chronic Kidney Disease, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: - - 2014
Brain atrophy has been reported in patients with end-stage renal disease receiving hemodialysis, although its mechanism is unknown. However, little is known regarding brain atrophy in patients receiving peritoneal dialysis (PD). Therefore, we examined brain volume and its annual change over 2 years in PD patients compared with patients with ...
Bellon Nathalia N Department of Dermatology, Hôpitaux Universitaires Henri Mondor, Créteil, - - 2014
Background: The value of anti-desmoglein 1 and 3 (Dsg1, Dsg3) enzyme-linked immunosorbent assay (ELISA) is controversial in the follow-up of pemphigus. Objective: To evaluate anti-desmoglein ELISA (Dsg ELISA) in the follow-up of pemphigus and compare ELISA with direct and indirect immunofluorescence in complete remission (CR). Methods: We performed a retrospective ...
Tavano Francesca - - 2014
BackgroundPancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy, characterized by largely unsatisfactory responses to the currently available therapeutic strategies. In this study we evaluated the expression of genes involved in gemcitabine uptake in a selected cohort of patients with PDAC, with well-defined clinical-pathological features.MethodsmRNA levels of hENT1, CHOP, MRP1 ...
Li Lin L Department of Dermatovenereology, Chengdu Second People's Hospital, No. 165, Caoshi Street, Chengdu, 610017, Sichuan, - - 2014
TNF-like ligand 1A (TL1A), a newly identified member of the TNF superfamily, has been proved as an important mediator of inflammation and critically involved in the pathogenesis of rheumatoid arthritis and several other autoimmune diseases. The aim of our study was to determine the possible role of TL1A in the ...
Prattes Juergen J Medical university of Graz, Section of Infectious Diseases, Graz, Austria ; - - 2014
Objectives Invasive pulmonary aspergillosis has been increasingly reported in non-neutropenic patients including those with underlying respiratory diseases. We compared the diagnostic performances of Galactomannan, 1,3-beta-D-glucan, and Aspergillus-specific lateral-flow device tests with that of conventional culture by using bronchoalveolar lavage fluid samples from patients with underlying respiratory diseases. Methods We analyzed ...
Timerbaeva Sofia L SL Department of Neurogenetics , and 2 Laboratory for Medical Statistics, Research Center of Neurology, Russian Academy of Medical Sciences (Volokolamskoye Shosse 80, Moscow 125367, Russia - - 2014
Abstract Purpose/Aim of the study - To analyze contribution of rs3842225 and rs1182 single nucleotide polymorphisms (SNP) in TOR1A gene, the causative gene for the DYT1 form of hereditary early-onset generalized dystonia, to the development of focal and segmental dystonia in Russian patients. Materials and methods - We analyzed associations ...
Jung Su Kyung SK Department of Ophthalmology and Visual Science, The Catholic University of Korea, Seoul St. Mary's Hospital, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, - - 2014
We compared the oxidative stress and antioxidant capacities of the medial rectus muscles (MRMs) between the patients with constant exotropia and control subjects. A total of 40 MRMs from patients with constant exotropia and 40 MRMs from normal donor eyes (controls) were assessed. Neuronal nitric oxide synthase (nNOS), superoxide dismutase ...
Marthey L L Kremlin Bicêtre University Hospital, Assistance Publique-Hopitaux de Paris (AP-HP), Paris-Sud University, Le Kremlin Bicêtre; Antoine Béclère University Hospital, AP-HP, Paris-Sud University, Clamart, - - 2014
Recently, a new enteropathy has been described: olmesartan-associated enteropathy. However, the association has been questioned: a phase 3 trial and a cohort study found no association between gastrointestinal events and olmesartan. We collected French cases of sartan-associated enteropathy to describe further this entity, confirm or refute causality, and determine if ...
Laursen Tea Lund TL Department of Hepatology and Gastroenterology, Aarhus University Hospital, - - 2014
The complement system is activated in liver diseases including acute liver failure (ALF); however, the role of the lectin pathway of complement has scarcely been investigated in ALF. The pathway is initiated by soluble pattern recognition molecules: mannan-binding lectin (MBL), M-, L- and H-ficolin and collectin-liver-1 (CL-L1), which are predominantly ...
Astan Ramazan R Department of Cardiology, Batman Regional State Hospital, Batman, - - 2014
Cardiovascular complications are the leading causes of premature deaths in hemodialysis patients. Due to rapid changes in volume and electrolyte concentration following dialysis, the some electrocardiographic (ECG) changes or arrhythmias might be seen. To investigate the acute effects of hemodialysis on the ECG parameters in patients with chronic end-stage renal ...
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