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Results 551 - 600 of 3366
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Shoukat Department of Nephrology, Sindh Institute of Urology and Transplantation, - - 2014
To determine the frequency and leading factors of pulmonary hypertension among chronic hemodialysis patients. Case series. Hemodialysis Unit, Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, from September 2011 to March 2012. Patients of either gender aged between 16 to 60 years of age undergoing hemodialysis for at ...
Ziraman Ipek I 1 Department of Radiology, Ankara Numune Training and Research Hospital , Ankara, Turkey - - 2014
Abstract Crimean-Congo hemorrhagic fever (CCHF) is a fatal viral infection that involves multiple organs, and endothelium. We described abdominal sonographic findings of the patients infected with the Crimean-Congo hemorrhagic fever virus (CCHFV) in relation to the severity of the disease. This is a prospective study performed among hospitalized patients infected ...
Santos Jasper Guimarães JG Departamento de Neurologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo SP, - - 2014
Objective (1) To evaluate whether the Nine Items Questionnaire (WOQ-9) for the detection of wearing-off (WO) in Parkinson Disease (PD), by means of its screening ability, is a helpful tool to assist neurologists in diagnosing WO; (2) To determine the sensitivity and the specificity of a free Brazilian Portuguese translation ...
Liu Fengqiong F Department of Epidemiology and Health Statistics (FL), School of Public Health, Fujian Medical University; Department of Nutrition (FL, WL), School of Public Health, Sun Yat-Sen University; and Department of Cardiology (RL, YZ, JQ), Guangzhou Military Region General Hospital, Guangzhou, Guangdong Province, P.R. - - 2014
Circulating microRNAs (miRNAs) have already been proposed as sensitive and informative biomarkers for the diagnosis of multiple diseases. We investigated the miRNA expression patterns in plasma samples of patients with coronary artery disease (CAD) and explored the potential functions of certain miRNAs.Deep sequencing analysis was performed to determine the miRNA ...
Wei Ping P From the Department of Respiratory Medicine (PW, H-WL, L-CF, H-PL, J-FX); and Department of Radiology (SJ), Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai - - 2014
Pulmonary Langerhans cell histiocytosis (PLCH) is a rare disease with insidious onset and nonspecific manifestations. The objective of this article was to characterize the clinical manifestations and features of PLCH by retrospectively analyzing clinical data of patients with PLCH in addition to simultaneous review of literature.A retrospective analysis was conducted ...
Rachakonda Vikrant V Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, - - 2014
Dysregulated adipose tissue metabolism has been implicated in the pathogenesis of alcoholic liver disease in murine models. We aimed to characterize serum markers of adipose tissue metabolism and inflammation in patients with severe acute alcoholic hepatitis (AAH) and determine their utility to predict survival in severe AAH. A prospective, case-control ...
Chen Yufan Y Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, - - 2014
Cushing's disease (CD) presents a remarkable preponderance in female gender, and a significant minority of patients with CD presented with negative magnetic resonance imaging (MRI) findings. The aim of this study was to evaluate gender-related and MRI classification-related differences in clinical and biochemical characteristics of CD. We retrospectively studied 169 ...
Tamargo Juan J Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid, 28040, - - 2014
Hyperkalemia (serum potassium >5.5 mmol/L) may result from increased potassium intake, impaired distribution between the intracellular and extracellular spaces, and/or reduced renal excretion. Renin-angiotensin-aldosterone system inhibitors (RAASIs) represent an important therapeutic strategy in patients with hypertension, heart failure, chronic kidney disease, and diabetes, but hyperkalemia is a key limitation to ...
Tseliou Eleni E Third Department of Cardiology, University of Athens School of Medicine, Athens, - - 2014
Advanced heart failure (HF) is associated with increased morbidity and mortality; traditionally used prognostic factors often fail to predict the outcome. Increased red blood cell distribution width (RDW) has recently been recognized as an important unfavorable prognostic factor in HF, independent of anemia; however, the role of RDW in patients ...
Ofer-Shiber Shachaf S From the Department of Internal Medicine (SO-S); Rheumatology Unit, Beilinson Hospital, Rabin Medical Center (YM); and Sackler Faculty of Medicine, Tel Aviv University (SO-S, YM), Tel Aviv, - - 2014
The aim of this study is to determine the effect of comorbidity assessed by the Charlson comorbidity index (CCI) at the time of diagnosis on the outcome of antineutrophil cytoplasmatic antibody (ANCA) associated vasculitis (AAV).This is a longitudinal observational study of 30 consecutive patients with AAV who were diagnosed and ...
Ravi Anupama A Division of Allergic Diseases, and Mayo Center for Mast Cell and Eosinophil Disorders, Mayo Clinic, Rochester, Minn. Electronic address: - - 2014
Mast cell activation syndrome (MCAS) describes patients with episodes of mast cell mediator release, with negative bone marrow biopsy results, and the failure to meet the criteria for systemic mastocytosis. Identify elevation of mast cell mediators of patients with MCAS. We performed a retrospective study of 25 patients with MCAS ...
Zhao Hongjie - - 2014
The purpose of this retrospective study was to evaluate the clinical value of serum cytokeratin-19-fragment (cyfra21-1) as a biomarker in nonsmall cell lung cancer (NSCLC). Sixty-six patients with NSCLC and 48 cases with benign lung disease were retrospectively analyzed in the department of thoracic surgery in our hospital. The serum ...
Vasiliou Charalampos C Charalampos Vasiliou, MD, is Specialist, Gastroenterology Department, Ippokration University General Hospital, Athens, Greece. Vasiliki Xiromeritou, PhD, MD, is Consultant, Gastroenterology Department, Ippokration University General Hospital, Athens, Greece. Georgia Kafiri, PhD, MD, is Director, Pathology Department, Ippokration University General Hospital, Athens, Greece. George Papatheodoridis, PhD, MD, is Associate Professor, Internal Medicine Department, Ippokration University General Hospital, Athens, - - 2014
The associations between symptoms and endoscopic findings have not been clearly defined. We aimed to assess the associations of reflux dyspepsia and/or symptoms with specific endoscopic findings, histological findings, as well as the presence of Helicobacter pylori infection and its CagA subtype. A total of 160 patients with dyspeptic and/or ...
Lin Wen-Li WL Department of Pediatrics, Mackay Memorial Hospital, Taipei, - - 2014
Cerebrospinal fluid (CSF) cell count and biochemical examinations and cultures form the basis for the diagnosis of bacterial meningitis. However, some patients do not have typical findings and are at a higher risk of being missed or having delayed treatment. To better understand the correlation between CSF results and outcomes, ...
Cassaday Ryan D RD Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, - - 2014
Relapse is least common in patients with indolent B-cell malignancies (iB-NHL) who undergo nonmyeloablative allogeneic transplantation (NMAT) in complete remission (CR). However, for the many patients unable to achieve this state, outcomes are poorly described and methods to improve results are unknown. We sought to describe the long-term follow-up and ...
Turker Yasin Y Department of Cardiology, Duzce University Faculty of Medicine, Duzce, Turkey. Electronic address: - - 2014
Both high-sensitivity CRP (hs-CRP) and uric acid (UA) levels are known to be increased in heart failure patients and are associated with poorer functional capacity and adverse outcome. The role of these markers in patients with mitral regurgitation (MR) is less clear. The aim of this study was to assess ...
Rosario Pedro Weslley PW Santa Casa de Belo Horizonte, - - 2014
Objective To determine the value of acromegaly screening in adult patients not reporting enlargement of the extremities, but who present arterial hypertension associated with at least one other comorbidity of the disease. Subjects and methods Patients seen by general practitioners at primary health care units were evaluated. Among the patients ...
Duran Ayse Ocak AO Department of Medical Oncology, Faculty of Medicine, Erciyes University, Kayseri, - - 2014
Objective Thyroid volume and the prevalence of thyroid nodules are higher in patients with insulin resistance. A relationship between thyroid volume and glucose metabolism disorders (GMD) has not as yet been clarified. The present retrospective study aimed to investigate the association between GMD and thyroid volume. We investigated the data ...
Huang Wen-Hung WH From the Department of Nephrology and Division of Clinical Toxicology (W-HH, T-HY); Department of Internal Medicine (M-JC, Y-JS), Chang Gung Memorial Hospital, Linkou; and Chang Gung University College of Medicine (W-HH, T-HY), Taoyuan, - - 2014
Inflammation is highly prevalent among peritoneal dialysis (PD) patients. High-sensitivity C-reactive protein (hs-CRP) is the most widely used inflammatory marker in clinical medicine and is correlated with mortality in PD patients. Air pollution is associated with systemic inflammation. The aim of this cross-sectional study was to assess the role of ...
Kronbichler Andreas A From the Department of Internal Medicine IV (Nephrology and Hypertension) (AK, PS, GM); Department of Radiology (RF), Medical University Innsbruck, Innsbruck, Austria; Institute of Immunology (MK), University of Heidelberg, Heidelberg, Germany; 3rd Department of Medicine (AS, DC, ZP), Research Laboratory, Faculty of Medicine, Semmelweis University, Budapest, Hungary; and Department of Nephrology and Dialysis (KL), Academic Teaching Hospital Feldkirch, Feldkirch, - - 2014
Catastrophic antiphospholipid syndrome (CAPS) is a rare but devastating complication in patients with antiphospholipid syndrome (APS) with a high morbidity and mortality.We describe a case of a 30-year old female patient with immunoglobulin A (IgA) deficiency who underwent splenectomy because of idiopathic thrombocytopenic thrombocytopenia. Subsequently, an APS and finally systemic ...
Lee Jeong Gil JG Department of Anesthesiology and Pain Medicine, Kosin University College of Medicine, Busan, - - 2014
Unlike the right internal jugular vein (RIJV), there is a paucity of data regarding the effect of the Trendelenburg position on the left internal jugular vein (LIJV). The purpose of this study is to investigate the cross-sectional area (CSA) of the LIJV and RIJV and their response to the Trendelenburg ...
Seyahi Emire E Division of Rheumatology, Department of Medicine, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul, Turkey 81310. Electronic address: - - 2014
Behçet's syndrome (BS) is a well-recognized cause of Budd-Chiari syndrome (BCS); however, information about its clinical characteristics and outcome is limited. We reviewed the records of about 9000 patients with BS registered at the multidisciplinary Behçet's syndrome outpatient clinic at Cerrahpasa Medical Faculty between July 1977 and October 2013. We ...
Cebeci F F Department of Dermatology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey. - - 2014
The pathogenesis of thrombosis in Behçet's Disease (BD) is unknown, however, multiple factors leading to the disease may include hypercoagulability, hypofibrinolysis and endothelial injury. We sought to evaluate the frequency of erythema nodosum-like lesions (ENLL) due to the presence of vasculitis in ENLL observed in BD in male patients with ...
Bo L L Intensive Care Unit, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China. - - 2014
We tested therapeutic efficacies of different hemoperfusion frequencies in patients with acute severe organophosphate poisoning (ASOP). 36 patients with ASOP were enrolled in this study and divided into two groups. Patients in the repeated hemoperfusion group (n = 20) received 3-4 hemoperfusions within 48 hours after poisoning, while other patients ...
Eng Oliver S OS 1 Departments of Surgery, 2 Departments of Biostatistics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, - - 2014
Thyromegaly and thyroid nodules are known to cause compressive symptoms, but the exact relationship between nodule size and development of compressive symptoms is unclear. We sought to determine whether compressive symptoms are directly related to nodule size. A retrospective analysis of 99 patients who underwent thyroidectomy by a single surgeon ...
Yousefi Maryam M Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Alopecia areata (AA) is a common type of hair loss with an autoimmune basis. As the role of homocysteine (Hcys), folate, and CRP has been considered in some autoimmune diseases. To evaluate homocysteine, folate and CRP level in AA. This study was performed on 29 patients who had AA for ...
Warnke Clemens C From the Department of Neurology (C.W., T.D., K.W., V.I.L., H.-P.H., B.C.K.), Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany; and Department of Clinical Neuroscience (R.R., C.H., N.N., T.O.), Karolinska Institute, Stockholm, - - 2014
To assess whether pretreatment-lymphocyte counts, treatment before fingolimod, age, sex, or body mass index (BMI) affects the risk of fingolimod-induced lymphopenia in patients with relapsing-remitting multiple sclerosis (RRMS). Data were obtained from a German multicenter, single-arm, open-label study of patients with RRMS treated with fingolimod, and findings were validated in ...
Kraszewska Agnieszka A Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, - - 2014
An important side effect of lithium therapy is an influence on thyroid function. It is unclear whether there is a significant association between thyroid function and duration of lithium administration. The aim of the present cross-sectional study was to measure levels of thyroid hormones and antibodies in patients with bipolar ...
Lim Nigel C S NC Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, - - 2014
To study the demographics, comorbidities, clinical manifestations and treatment methods of thyroid eye disease (TED) in Singapore. In this retrospective case series, we analysed the case records of all patients with TED who presented at our multidisciplinary Thyroid Eye Clinic from November 2002 to October 2012. There were a total ...
Walbert Tobias T Department of Neurosurgery and Neurology, Henry Ford Health System Detroit, 2799 W Grand Blvd, Detroit, MI, 48202, USA, - - 2014
Ependymoma is a rare central nervous system tumor of adults. Reports of patient symptoms, interference patterns and costs encountered by patients and families are limited. Adult ependymoma patients completed the online Ependymoma Outcomes Questionnaire II. The survey assesses disease and functional status as well as socio-economic factors. Descriptive statistics were ...
Gary T T Division of Vascular Medicine, Department of Internal Medicine, Medical University of Graz, Graz, - - 2014
The lymphocyte-to-monocyte ratio (LMR) is easily determined from the white blood cell count. Lymphocytes were previously investigated as a part of the neutrophil-to-lymphocyte ratio (NLR) in patients with atherosclerotic disease and an elevated NLR was negatively associated with cardiovascular endpoints. As monocytes play a leading role in the progression of ...
Lea Simon S The University of Manchester; Manchester Academic Health Science Centre; University Hospital South Manchester NHS Foundation Trust; NIHR South Manchester Respiratory and Allergy Clinical Research Facility, Manchester, M23 - - 2014
Some asthma patients remain symptomatic despite using high doses of inhaled corticosteroids. We used alveolar macrophages to identify individual patients with insensitivity to corticosteroids, and to evaluate the anti-inflammatory effects of a p38 MAPK inhibitor combined with a corticosteroid on these cells. Alveolar macrophages from 27 asthma patients (classified according ...
Sun Xuefeng X Department of Pulmonary Medicine, Peking Union Medical College Hospital, Beijing, - - 2014
Pulmonary sequestration (PS) is a rare congenital malformation. This study presents the characteristics of PS in adult patients, including pulmonary function and concurrent infection, which have not been well documented previously. Patients ≥16 years old with a discharge diagnosis of PS from Peking Union Medical College Hospital between January 1990 ...
Wang Zhi-Wei ZW Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing - - 2014
Objective To assess the feasibility and effectiveness of transarterial embolization for management of acute massive hemorrhage in patients with duodenal ulcer. Methods Twenty-two patients with duodenal ulcer underwent transarterial embolization for acute massive hemorrhage in our hospital between January 2007 and December 2012. Embolic agents were coils and gelatin sponge. ...
de Luis Daniel Antonio DA Center of Investigation of Endocrinology and Nutrition, Medicine School and Department of Endocrinology and Nutrition, Hospital Clinico Universitario, University of Valladolid, Simancas, - - 2014
Background: The role of glucagon-like peptide 1 (GLP-1) variants in metabolic syndrome (MS) and its components remains unclear in obese subjects. Objective: The aim of our study was to evaluate the relationship of rs6923761 with MS and its components in obese subjects. Design: A population of 1,122 obese subjects was ...
Lim Mie Jin MJ Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, - - 2014
Our aim was to assess whether short-term treatment with soluble tumor necrosis factor (TNF) receptor affects circulating markers of bone metabolism in rheumatoid arthritis (RA) patients. Thirty-three active RA patients, treated with oral disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids for > 6 months, were administered etanercept for 12 weeks. Serum ...
Berkes Eniko E Department of Obstetrics and Gynaecology, Justus-Liebig-University, 35392 Giessen, Germany. Electronic address: - - 2014
To study if neutrophil extracellular traps (NETs) are present in the peritoneal fluid of endometriosis patients. NETs play a crucial role in fighting against microorganisms. However, exaggerated NET production may lead to tissue damage in their vicinity in pathological conditions. Our study evaluates the presence of NETs in endometriosis peritoneal ...
Naoura Iptissem I Department of Gynaecology and Obstetrics, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Institut Universitaire de Cancérologie, Université Pierre et Marie Curie Paris 6, France. Electronic address: - - 2014
While the accuracy of the Sentinel Lymph Node (SLN) procedure has been validated in patients with early-stage endometrial cancer (EC) at low and intermediate risk of recurrence, its relevance for high-risk EC remains unknown. The aim of this study was to evaluate the contribution of SLN biopsy in staging patients ...
Rivard Lena L Department of Cardiology at the Montreal Heart Institute and the Université de Montréal, Montreal, Canada. Electronic address: - - 2014
Electrophysiological predictors of atrioventricular (AV)-block after transcatheter aortic valve replacement (TAVR) are unknown. To assess the value of electrophysiological study (EP)-study before and after TAVR. Seventy-five consecutive pacemaker-free patients undergoing TAVR at the Montreal Heart Institute were prospectively studied. Eleven patients (14.7%) developed AV-block during the index hospitalization and 3 ...
Bonello Michael M Walton Centre for Neurology and Neurosurgery, Liverpool, - - 2014
We describe a patient who developed significant cognitive decline with profound amnesia following non-dominant temporal lobectomy for refractory seizures, in whom the original suspicion of structural pathology was revised following the discovery of clinical and neuropathological markers of inflammation, neuropsychological evidence of bilateral involvement, and high titres of antibodies directed ...
Desai Laxmikant L Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632 004, - - 2014
Hypogammaglobulinemia, a form of primary immunodeficiency, is an uncommon condition. Gastrointestinal (GI) symptoms may be the only presentation. A series of 22 patients who presented with GI symptoms and were diagnosed with hypogammaglobulinemia is presented. Chronic diarrhea was the presentation in majority (90.9 %) of patients. Malabsorption was identified in 87.5 % ...
Hettinga Ymkje M YM Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the - - 2014
Tubulointerstitial nephritis and uveitis (TINU) syndrome is characterized by tubulointerstitial and ocular inflammation. Thus far, the value of noninvasive diagnostic tests is not known. To determine whether urinary β2-microglobulin (β2M), urinary protein, and serum creatinine have predictive value for detecting TINU syndrome in young patients with uveitis. This prospective cohort ...
Barry J A JA Institute for Women's Health, University College London Medical School , London , - - 2014
The aim of this systematic review and meta-analysis was to assess any difference in the self-ratings of hostility in mentally healthy women with different levels of prolactin (PRL). Electronic databases (PubMed, MEDLINE, EMBASE and the Cochrane Library) were searched up to 2nd July 2012 for published literature comparing hostility levels ...
Buttini S S 1] Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Piemonte Orientale 'Amedeo Avogadro', Novara, Italy [2] Department of Translational Medicine, Section of Neurology, University of Piemonte Orientale 'Amedeo Avogadro', Novara, - - 2014
Perforin (PRF) has a key role in the function of cytotoxic T and natural killer cells. Rare variations of PRF1 predispose to autoimmunity. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease of the peripheral nervous system, involving defective lymphocyte apoptosis. The aim of this study was to investigate the ...
Miura Masanobu M Department of Cardiovascular Medicine, Tohoku University Graduate School of - - 2014
Background:Microalbuminuria, traditionally defined as urinary albumin/creatinine ratio (UACR) ≥30 mg/g, is a risk factor for mortality even in patients with preserved glomerular filtration rate (GFR). The prognostic impact of subclinical microalbuminuria, however, remains unknown in patients with chronic heart failure (CHF).Methods and Results:In the Chronic Heart Failure Analysis and Registry in the ...
Forel Jean-Marie JM Faculté de Médecine, Aix-Marseille Université, URMITE UMR CNRS 7278, 13005, Marseille, France, - - 2014
A specific biomarker of post-ARDS fibroproliferation could be useful in the identification of patients who could benefit from therapies aiming to modulate fibroproliferation such as corticosteroids.The aim of this prospective study was to determine the best threshold of the N-terminal-peptidetype III procollagen (NT-PCP-III) in non-resolving ARDS to validate this threshold ...
Lightfoot Andrew J AJ University of Pennsylvania, Urology, Philadelphia, Pennsylvania, United States ; - - 2014
INTRODUCTION We analyzed the trends of positive surgical margin (PSM) location in patients that had pT3 disease at robotic assisted radical prostatectomy (RARP). We aimed to describe our changing incidence of positive surgical margins in the largest series to date of patients with pT3 disease treated by RARP. METHODS A ...
Tateno Fuyuki F Neurology, Internal Medicine, Sakura Medical Center, Toho University, Sakura, - - 2014
Dementia with Lewy bodies (DLB) is the second most common degenerative cause of dementia, whereas lower urinary tract (LUT) function in DLB patients has not been fully delineated. We investigated LUT function in DLB by clinical-urodynamic observations. We examined 32 patients with DLB (23 men, 9 women; aged 59-86 [mean, ...
Niedziela Jacek J Third Department of Cardiology, Silesian Center for Heart Diseases, Medical University of Silesia, M. Curie-Skłodowskiej 9, 41-800, Zabrze, Poland, - - 2014
In the general population, the lowest mortality risk is considered to be for the body mass index (BMI) range of 20-24.9 kg/m(2). In chronic diseases (chronic kidney disease, chronic heart failure or chronic obstructive pulmonary disease) the best survival is observed in overweight or obese patients. Recently above-mentioned phenomenon, called obesity ...
Shen Qi Q Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, - - 2014
Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm, characterized by persistent monocytosis. Due to the lack of unique surface markers expressed by neoplastic monocytes and the frequent CD34-negative blast immunophenotype, the diagnostic value of flow cytometric immunophenotyping (FCI) in CMML is rarely studied. In this study, by using a multicolor ...
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