Search Results
Results 301 - 350 of 1522
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Audo Isabelle - - 2008
PURPOSE: To characterize the clinical, psychophysical, and electrophysiological phenotype of 19 patients with enhanced S-cone syndrome (ESCS) and relate the phenotype to the underlying genetic mutation. METHODS: Patients underwent ophthalmic examination and functional testing including pattern ERG, full-field ERG, and long-duration and short-wavelength stimulation. Further tests were performed in some ...
Shah Mufarriq - - 2008
OBJECTIVE: To assess the role of low vision devices in visual rehabilitation of patients with Stargardt's disease. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: The Khyber Institute of Ophthalmic Medical Sciences, Hayatabad Medical Complex, Peshawar, Pakistan, from June 2003 to June 2005. PATIENTS AND METHODS: Patients diagnosed as ...
Christodoulakis Emmanouil V - - 2008
Three patients with recent central retinal vein occlusion underwent vitrectomy, fluid-air exchange, and a 50-microg tissue plasminogen activator intravitreal injection. After a mean follow-up period of 38.7 weeks, no patient's vision improved and one patient required an additional vitrectomy. Post-vitrectomy tissue plasminogen activator injection did not improve the course of ...
Stuebiger Nicole - - 2008
PURPOSE: In acute retinal necrosis, which is caused by herpes virus, urgent treatment is essential. DESIGN AND METHODS: Here we present a 47 years old male patient, who developed an acute retinal necrosis in his left eye. Therapy was initiated with systemic aciclovir and corticosteroids. RESULTS: During the course of ...
Haider Syed - - 2008
The aim of this study was to establish the causes of leukocoria in pediatric patients in a tertiary hospital environment. All patients younger than 10 years who presented with leukocoria between January 1, 1999, and December 31, 2000, were included in the study; 39 (55%) patients were boys and 32 ...
Rossi T - - 2008
PURPOSE: To calculate the reliability of an eye-dedicated triaging system named Rome Eye Scoring System for Urgency and Emergency (RESCUE). METHODS: There were four coding parameters: pain, redness, loss of vision, and risk of open globe. Each parameter is assigned a score, the sum of which allows color coding. There ...
Bainbridge James W B - - 2008
Early-onset, severe retinal dystrophy caused by mutations in the gene encoding retinal pigment epithelium-specific 65-kD protein (RPE65) is associated with poor vision at birth and complete loss of vision in early adulthood. We administered to three young adult patients subretinal injections of recombinant adeno-associated virus vector 2/2 expressing RPE65 complementary ...
Maguire Albert M - - 2008
Leber's congenital amaurosis (LCA) is a group of inherited blinding diseases with onset during childhood. One form of the disease, LCA2, is caused by mutations in the retinal pigment epithelium-specific 65-kDa protein gene (RPE65). We investigated the safety of subretinal delivery of a recombinant adeno-associated virus (AAV) carrying RPE65 complementary ...
Hajali M - - 2009
To determine the prevalence of cystoid macular oedema (CME) by optical coherence tomography (OCT) in retinitis pigmentosa (RP) patients with no evidence of cystic macular lesions on fundus examination. We included 63 RP patients with no evidence of cystic-appearing macular changes on fundus examination. All patients underwent a complete ocular ...
Walia S - - 2009
To evaluate the prevalence of cystic macular lesions in patients with Usher II syndrome. All Usher type II patients seen in the inherited eye disease clinic at the University of Illinois at Chicago between January 2002 and December 2007 were included (n=76). Each participating patient underwent a detailed clinical examination, ...
Heckenlively John R - - 2008
Three main forms of autoimmune retinopathy (AIR) have been identified over the last 15 years: cancer-associated retinopathy (CAR), melanoma-associated retinopathy (MAR), and nonneoplastic autoimmune retinopathy (npAIR). In this chapter, the term AIR will be used to encompass all three disorders where there is commonality to their features. Complicating the issue ...
Jin Zi-Bing - - 2008
PURPOSE: To investigate macular hole (MH) formation in patients with retinitis pigmentosa (RP) and to determine surgical prognosis for these patients. METHODS: Data for four RP patients with MHs were retrospectively reviewed. Comprehensive ocular examinations, including electroretinography, Goldmann perimetry, color funduscopy, B-scan ultrasonic tomography, and optical coherence tomography (OCT), were ...
Nozaki Kazuhiko - - 2008
OBJECTIVE: The aim of this study was to evaluate the effect of early optic canal unroofing on visual function in patients with meningiomas of the tuberculum sellae and planum sphenoidale. METHODS: We retrospectively reviewed the clinical records of 20 consecutive patients with tuberculum sellae meningiomas and two patients with planum ...
Lipski A - - 2008
BACKGROUND: Vision impairment in children and young adults may derive from choroidal neovascularisation (CNV) related to numerous conditions. The aim of this study is to highlight the applicability of photodynamic therapy using verteporfin (PDT) in these patients. METHODS: In 16 eyes of 16 consecutive patients aged 30 years or younger, ...
Bruce B B - - 2008
To evaluate racial differences in idiopathic intracranial hypertension (IIH). Medical records of all consecutive patients with definite IIH seen between 1989 and 2006 were reviewed. Demographics, associated factors, and visual function at presentation and follow-up were collected. Black patients were compared to non-black patients. We included 450 patients (197 black, ...
Crumbliss Kara E - - 2008
PURPOSE: To evaluate the prevalence of visual hallucinations in Charles Bonnet Syndrome (CBS) among patients at a Low Vision Clinic. To determine whether Low Vision Rehabilitation (LVR) intervention results in a decrease of these visual hallucinations. METHODS: We surveyed 50 consecutive new patients in a low vision clinic to determine ...
Kogure Akiko - - 2008
PURPOSE: To evaluate the retention of intravitreal triamcinolone acetonide (TA) particles and the efficacy of TA therapy for patients with cystoid macular edema in branch retinal vein occlusion (BRVO) or diabetic macular edema (DME). We monitored the TA particles until absorption from the vitreous cavity was complete. The correlation between ...
Feiz-Erfan Iman - - 2008
The rate of symptomatic improvement of visual symptoms associated with hematogenous metastases to the sella and pituitary was evaluated retrospectively in seven patients (five men, two women; mean age, 52.3 years) with primarily visual symptoms (diplopia alone in three, diplopia with blurred vision in one, blurred vision alone in one, ...
Malhotra Sumeet - - 2008
The purpose of this study was to determine clinical presentation, microbiological spectrum and visual outcome of cluster endophthalmitis patients after cataract surgery in central India. The records of cluster endophthalmitis patients were retrospectively reviewed. Three clusters of patients were identified who had undergone vitreous biopsy followed by three-port pars plana ...
De Silva Deidre A - - 2008
BACKGROUND AND PURPOSE: Patients with ischemic stroke have a high prevalence of hypertension and diabetes, which are major risk factors for potentially blinding retinal diseases. We studied the prevalence of retinal diseases, and the need for an ophthalmology referral, among persons with acute ischemic stroke. METHODS: We conducted a prospective ...
Herrera Waldo - - 2008
PURPOSE: To determine the retinal phenotype of Usher syndrome type III (USH3A) caused by clarin-1 (CLRN1) gene mutations in a non-Finnish population. METHODS: Patients with USH3A (n = 13; age range, 24-69) representing 11 different families were studied and the results compared with those from patients with USH2A (n = ...
Opremcak Emitchel - - 2008
BACKGROUND: Central retinal artery occlusion (CRAO) and branch retinal artery occlusion (BRAO) may be a result of platelet-fibrin emboli, cholesterol plaques, or calcific emboli that typically lodge at the bifurcation of retinal arterioles or at a location as the vessel narrows. Hollenhorst plaques (cholesterol emboli) can often be seen at ...
Riddoch M Jane MJ School of Psychology, University of Birmingham, Birmingham, UK. - - 2008
The performance of two patients with visual agnosia was compared across a number of tests examining visual processing. The patients were distinguished by having dorsal and medial ventral extrastriate lesions. While inanimate objects were disadvantaged for the patient with a dorsal extrastriate lesion, animate items are disadvantaged for the patient ...
Yeh Po-Ting - - 2008
OBJECTIVE: To investigate vitreous levels of reactive oxygen species (ROS) in patients with proliferative diabetic retinopathy (PDR) and analyze ROS levels among different groups of PDR patients. DESIGN: Retrospective case-control study. PARTICIPANTS: Thirty-nine eyes of 39 patients with PDR and 16 eyes of 16 non-PDR patients (control group) that underwent ...
Lincoff Harvey - - 2008
PURPOSE: To test the validity of the geometric conclusion that 40 degrees gaze down is optimal for pneumatic displacement of a subretinal hemorrhage (SRH) in the macula. METHODS: Nine consecutive patients with SRH in the macula had an intravitreal injection of perfluorocarbon gas sufficient to cover the macula when the ...
Byeon Suk Ho - - 2008
PURPOSE: To determine the incidence, demographic features, and clinical characteristics of polypoidal choroidal vasculopathy (PCV) in Korean patients. METHODS: A retrospective review was undertaken of 392 eyes of 321 symptomatic patients suspected of having exudative age-related macular degeneration (AMD) after their first visit to a tertiary hospital between February 2002 ...
Koh Seong-Beom - - 2008
BACKGROUND AND AIM: The extrastriate cortex is a visual processing structure beyond the striate cortex. This region contains cells that differ in selectivity for different features of stimuli such as color, motion and stereopsis. We studied stereopsis and color vision in patients with right extrastriate cerebral lesions. METHODS: Patients with ...
Meyer Carsten H - - 2008
PURPOSE: To evaluate the visual acuity (VA) of patients following intravitreal (IVT) injections. METHODS: 15 patients received 3 anti-vascular-endothelial-growth-factor (VEGF) injections on a monthly basis. Prior to each injection as well as 2 months after, the patients received a standardized examination including Snellen VA and optical coherence tomography (OCT). During ...
Aleci Carlo - - 2008
Purpose of the study was to compare Rarebit Perimetry (RP) with Standard Automatic Perimetry (SAP) in patients with ischemic retrochiasmal lesions. Seventeen patients with homonymous hemianopia underwent SAP and RP. Correlation between the two techniques was evaluated, congruent defects were quantified in the spared hemifield and residual vision areas were ...
Tamary H - - 2008
A congenital dyserythropoietic anaemia (CDA) was recognised in a French Caucasian male patient. Blood smears showed a pronounced aniso-poikilocytosis. Bone marrow light microscopy showed signs of dyserythropoesis, but no internuclear chromatin bridges. Electron microscopy disclosed erythroblast nuclei with the Swiss cheese aspect and the presence of cytoplasmic organelles, assessing the ...
Braun Erich H P - - 2008
PURPOSE: To evaluate the preoperative characteristics and postoperative outcomes of presbyopic and prepresbyopic patients selecting monovision correction by LASIK. DESIGN: Retrospective observational case series. PARTICIPANTS: One hundred seventy-two sequentially treated myopic and hyperopic patients, 45 years or older, who sought LASIK vision correction with the goal of monovision. METHODS: Patients ...
Violaris Konstantinos - - 2007
BACKGROUND: This study presents a family with hereditary cerebellar hemangioblastomas, as manifestations of the VHLD. METHODS: In a 20-year period, 7 members of a family, in 3 generations, developed symptoms of the VHLD with very high frequency and gene penetration. Six patients were operated for cerebellar hemangioblastomas. Two had previously ...
Janáky Márta - - 2008
OBJECTIVE: To analyze pattern electroretinograms (PERGs) and pattern visual evoked potentials (PVEPs) in retinitis pigmentosa (RP) patients. METHODS: PERGs and PVEPs were recorded in 106 eyes of 53 RP patients. A RETIport system was used for stimulation and recording. RESULTS: Reproducible PERGs were found in 17 (32%) of the patients, ...
Sarri Margarita M UCL Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London, WC1N 3AR, UK. - - 2008
Prism adaptation to rightward optical shifts during visually guided pointing is considered a promising intervention in right-hemisphere stroke patients with left spatial neglect. Conventionally, prism adaptation is assessed via aftereffects, on subjective straight ahead (SSA) pointing with eyes closed; or by visual open-loop pointing (VOL), i.e. pointing to a visual ...
Mantel Irmela - - 2008
Here we report the discovery of and phenotypic characterization of a retinal disorder of unknown origin in adults using clinical, electrophysiological and psychophysical techniques, and to seek the presence of circulating retinal autoantibodies in the sera of these patients. Sixteen patients were identified with progressive bilateral visual loss over a ...
Renner Agnes B - - 2008
PURPOSE: X-linked congenital retinoschisis (RS) is a relatively frequent retinal dystrophy associated with RS1 gene mutations. A negative electroretinogram (ERG), i.e., a b/a wave ratio <1.0 in the standard combined response, is considered a key diagnostic feature of RS. Only a few cases without a negative ERG have been reported. ...
Kedhar Sanjay R - - 2007
PURPOSE: To compare the clinical characteristics at presentation of multifocal choroiditis with panuveitis (MFCPU) and punctate inner choroidopathy (PIC). METHODS: A cross-sectional study of 66 patients (122 eyes) with MFCPU and 13 patients (22 eyes) with PIC was carried out. Diagnosis was based solely on retinal morphology. Demographic information, visual ...
Biancardi Ana Luiza - - 2007
PURPOSE: The association of retinal vein occlusion and hereditary thrombophilia abnormalities is not established, with controversial results in the literature. This study investigates the association between retinal vein occlusion and three thrombophilic mutations: factor V 1691A (factor V Leiden), prothrombin 20210A (PT 20210A) and homozygous methylenetetrahydrofolate reductase 677T (MTHFR 677TT). ...
AltintaƟ Ozgül - - 2008
BACKGROUND: To measure the parapapillary retinal nerve fiber layer and macular thickness and macular volume in vivo and to evaluate whether retinal structural changes and visual cortical responses may be related to the clinical severity of the PD. METHODS: We included 17 patients with Parkinson's disease and 11 healthy subjects ...
Newman Wright B - - 2007
We investigated the possible benefit for 26 patients with multiple sclerosis of placing Intuitive Overlays (spectral filters) over the page during reading and visual search. Initially all patients were allowed to select an overlay of a colour that reduced perceptual distortion and were tested with and without that overlay. With ...
Polati Mariza - - 2007
OBJECTIVE: To analyze the hypothesis that a reduction in sensitivity of the nasal visual hemifield would lead to an increase in the nasotemporal asymmetry of the visual field in patients under two years of age with early-onset convergent strabismus in comparison with normal patients. METHODS: Both eyes of 66 patients ...
Salvarani Carlo - - 2007
OBJECTIVE: To investigate potential associations of the PlA1/A2 polymorphism of the platelet glycoprotein IIIa (GPIIIa) gene with susceptibility to, and clinical expression of, giant cell arteritis (GCA). METHODS: One hundred forty patients with biopsy-proven GCA who were residents of Reggio Emilia, Italy, and 241 population-based healthy controls from the same ...
Aisenbrey Sabine - - 2007
OBJECTIVE: To assess long-term functional and morphological changes after macular translocation in patients with exudative age-related macular degeneration. METHODS: Evaluation of a noncomparative cohort study of 90 patients with a follow-up of 14 to 79 months (mean, 38.2 months). RESULTS: Visual acuity increased by 3 or more lines in 15 ...
Pitz Susanne - - 2007
OBJECTIVE: To describe the progression of ocular changes in patients with mucopolysaccharidosis I receiving enzyme replacement therapy. METHODS: Three male and five female patients with mucopolysaccharidosis I were followed up for 4 years while undergoing enzyme replacement therapy with alpha-l-iduronidase (Aldurazyme). Visual acuity, corneal clouding, intraocular pressure, ophthalmoscopy, and optic ...
Walia Saloni - - 2007
PURPOSE: To determine, with the use of optical coherence tomography (OCT), the peripapillary retinal nerve fiber layer (RNFL) thickness among patients with retinitis pigmentosa (RP) of different degrees of disease severity. METHODS: One eye in each of 25 RP patients was included. All patients underwent complete ocular examination, including the ...
Preechawat Pisit - - 2007
PURPOSE: To characterize anterior ischemic optic neuropathy (AION) in patients younger than 50 years. DESIGN: Retrospective study. METHODS: Records of all AION patients seen between 1989 and 2006 were reviewed. Patients younger than 50 years when initial visual loss occurred were included. RESULTS: Of 727 consecutive patients with AION, 169 ...
Hartong Dyonne T - - 2007
OBJECTIVE: Recently, it was discovered that subjects who showed a prolonged response suppression on their electroretinogram (ERG) and had symptoms of photophobia, problems adjusting to bright light, and difficulties seeing moving objects shared a mutation in the RGS9 (regulator of G-protein signaling 9) gene that is involved in the deactivation ...
Karmisholt Marianne Kirkegaard - - 2008
Intraocular infection is a feared complication in patients with candidaemia. We therefore assessed the current risk and prognosis in Danish candidaemia patients. Candidaemia patients at a Danish university hospital were identified prospectively during a 10-y period, 1995-2004, and ophthalmologic records were retrieved retrospectively. Among 203 incident cases of candidaemia, 86 ...
Hwang Joon Seo - - 2007
PURPOSE: To study the clinical characteristics of multiple sclerosis and associated optic neuritis in Korean children. METHOD: A retrospective analysis was performed on 10 patients with an onset of multiple sclerosis before age 16. Information on sex, age of onset, clinical course, laboratory findings, and clinical characteristics of optic neuritis ...
Sobrin Lucia - - 2007
PURPOSE: To report outcomes of off-label use of intravitreal clindamycin in the treatment of toxoplasmic retinochoroiditis. METHODS: In a noncomparative, retrospective, interventional case series, we reviewed the charts of six consecutive patients with toxoplasmic retinochoroiditis who were treated with intravitreal injection of clindamycin (1.0 mg/0.1 mL) because of intolerance to ...
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