Search Results
Results 201 - 250 of 1537
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Huang Jingjing - - 2010
BACKGROUND: The optical coherence tomography (OCT) and clinical characteristics of traumatic macular holes (TMHs) can be compared to those of idiopathic macular holes (IMHs) to gain insights into the pathogenesis of both. METHODS: The demographic data and visual acuity of 73 consecutive patients with unilateral, full-thickness TMHs and 182 consecutive ...
Ho Joseph J New England Eye Center, Tufts Medical Center, Boston, Massachusetts, - - 2010
PURPOSE. To investigate the characteristics of a spectral-domain optical coherence tomography (SD-OCT) image phenomenon known as the mirror artifact, calculate its prevalence, analyze potential risk factors, measure severity, and correlate it to spherical equivalent and central visual acuity (VA). METHODS. OCT macular cube 512 x 128 scans taken between January ...
Jayasundera Thiran - - 2010
PURPOSE: To investigate the prevalence of a peripapillary dark choroid ring on fluorescein angiography (FA) and the associated clinical features in patients with Stargardt disease. DESIGN: Retrospective review of 135 patients with Stargardt disease. METHODS: The presence or absence of a peripapillary dark choroid ring on FA was noted and ...
Fonollosa A - - 2010
To investigate whether interleukine-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) are related with macular oedema in patients with branch retinal vein occlusions (BRVOs). Retrospective case-control study. Nineteen patients who had macular oedema due to BRVO and nine patients with non-ischaemic ocular diseases (control group). Macular oedema was examined by optical ...
Rencová Eva - - 2011
Purpose:  To evaluate the influence of haemorheopheresis on anatomical and functional findings in patients with soft-drusen maculopathy. Methods:  We investigated 29 eyes (16 patients) and randomized 25 eyes (16 controls) with soft-drusen maculopathy [soft, confluent and reticular drusen, drusenoid retinal pigment epithelium detachment (RPED)]. Each patient received a series of ...
Sinha Manish Kumar - - 2010
BACKGROUND: Vision impairment is a devastating complication of tuberculous meningitis. In the present study we evaluated the predictors and prognostic significance of vision impairment in tuberculous meningitis. METHODS: In this study, 101 adult patients with tuberculous meningitis were evaluated for vision status and physical disability and were followed up for ...
Gr?nlund M A - - 2010
AIM: To describe ophthalmological phenotypes in patients with mitochondrial disease and known genotypes. METHODS: A retrospective study was performed on 59 patients (29 male, 30 female) with a mean age of 11.8 years who had mitochondrial disease with known DNA mutations. Fifty-seven of the 59 subjects underwent a detailed ophthalmological ...
Giganti Monica - - 2010
PURPOSE: To determine the tolerability of intravitreal infliximab (Remicade) in patients with refractory diabetic macular edema or choroidal neovascularization secondary to age-related macular degeneration. METHODS: This is a prospective, interventional, noncomparative, open-label, 12-week pilot study of intravitreal infliximab in four patients who failed conventional therapies. Two had diabetic macular edema ...
Saj A - - 2010
In spatial neglect, the pathological ipsilesional deviation of the subjective straight ahead (SSA) received both 'translational' and 'rotational' interpretations. Furthermore, hemianopia per se could also influence straight-ahead (SA) perception. Here, we aimed at disentangling the relative effects of neglect and hemianopia on the SSA by using a method analyzing translation ...
Garcia-Martin Elena - - 2010
PURPOSE: To quantify changes in the retinal nerve fiber layer (RNFL) of patients with multiple sclerosis (MS) over a 1-year time period and to compare the ability of noninvasive diagnostic imaging devices and visual evoked potentials (VEP) to detect axonal loss in these patients. METHODS: Eighty-one patients with MS underwent ...
Bruno Marie-Aurélie - - 2010
BACKGROUND: Assessment of visual fixation is commonly used in the clinical examination of patients with disorders of consciousness. However, different international guidelines seem to disagree whether fixation is compatible with the diagnosis of the vegetative state (i.e., represents "automatic" subcortical processing) or is a sufficient sign of consciousness and higher ...
Acharya Shrikrishna V - - 2010
To review our experience with long-term cabergoline and bromocriptine therapy in the treatment of giant prolactinomas. Patients with giant prolactinomas diagnosed and treated at our center in Mumbai, India, between January 2005 and January 2009 were included. Diagnostic criteria for giant prolactinoma included tumor diameter greater than 40 mm, serum ...
Theocharis Ip - - 2010
To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD). FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded; No ...
Emarah Ahmed M - - 2010
Arteriogenic erectile dysfunction (ED) is a target organ disease of atherosclerosis, and therefore might be a predictor of systemic atherosclerosis. Being systemic, it might be possible to evaluate the extent of atherosclerosis from retinal vascular findings. We investigated the possible correlation between penile cavernosal artery blood flow and retinal vascular ...
Chen Eric - - 2010
While the long-term incidence of hydroxychloroquine (HCQ) retinopathy is low, there remains no definitive clinical screening test to recognize HCQ toxicity before ophthalmoscopic fundus changes or visual symptoms. Patients receiving HCQ were evaluated with spectral domain optical coherence tomography (SD OCT) to assess the feasibility of identifying HCQ retinopathy at ...
Chan-Kai Brian T - - 2010
Transplant chorioretinopathy is a rare complication following solid organ or bone marrow transplantation and can result in severe vision loss. This series presents electroretinogram (ERG) results in patients with this condition. Patients who presented with bilateral vision loss following bone marrow or solid organ transplantation were identified. A complete ophthalmologic ...
Coppola Gianluca - - 2010
Medication-overuse headache (MOH) is a frequent, disabling disorder. Despite a controversial pathophysiology convincing evidence attributes a pivotal role to central sensitization. Most patients with MOH initially have episodic migraine without aura (MOA) characterized interictally by an absent amplitude decrease in cortical evoked potentials to repetitive stimuli (habituation deficit), despite a ...
Li Yonghui - - 2010
Although there is increasing evidence suggesting that there may be subtle abnormalities in idiopathic generalized epilepsy (IGE) patients using modern neuroimaging techniques, most of these previous studies focused on the brain grey matter, leaving the underlying white matter abnormalities in IGE largely unknown, which baffles the treatment as well as ...
Jeffery Douglas R - - 2010
Dalfampridine sustained-release (SR) is a time-release formulation of 4-aminopyridine, recently approved by the Food and Drug Administration to improve walking in patients with multiple sclerosis (MS). In Phase II trials, walking speed and lower extremity muscle strength was increased in patients with MS, but the increase in walking speed did ...
Kollar Branislav B 1st Department of Neurology, University Hospital, Comenius University, Bratislava, Slovakia. - - 2010
Authors warn of difficulties in diagnostic of solitary epileptic seizure and epilepsy. Our groups have been made up of patients, who have been dismissed from our clinic in the period from January 1997 to January 2007 with diagnosis of solitary unprovoked epileptic seizure (n=84) and epilepsy with sporadic epileptic seizure ...
Sturm Veit - - 2010
PURPOSE: We report the longterm follow-up of children with optic nerve avulsion (ONA) caused by traumatic events. The remarkable differences in courses and outcomes may elucidate the spectrum of ONA-associated symptoms and injuries. METHODS: During the last 15 years, three children with ONA were referred to our department. These cases ...
Henkin Robert I - - 2011
Olfactory and gustatory distortions in the absence of odors or tastants (phantosmia and phantageusia, respectively) with accompanying loss of smell and taste acuity are relatively common symptoms that can occur without other otolaryngologic symptoms. Although treatment of these symptoms has been elusive, repetitive transcranial magnetic stimulation (rTMS) has been suggested ...
Sanders Donald R - - 2010
To assess the efficacy of the Tetraflex (Lenstec Inc) intraocular lens (IOL) to provide enhanced near reading ability and spectacle independence relative to a monofocal control IOL in bilaterally implanted eyes tested binocularly. A prospective, age-matched, non-randomized US Food and Drug Administration clinical trial of 255 Tetraflex and 101 monofocal ...
Pitz Susanne - - 2009
BACKGROUND: Fabry disease is a rare X-linked lysosomal storage disorder, caused by the deficiency of alpha-galactosidase A. Ophthalmic features comprise a cornea verticillata, conjunctival aneurysms, tortuous conjunctival and/or retinal vessels, and anterior and posterior subcapsular cataracts. The issue of a possible subclinical optic neuropathy in Fabry disease has been raised ...
Bengtsson Boel - - 2009
OBJECTIVE: To investigate how well short-term progression rates can predict long-term visual field outcomes in patients with glaucoma. METHODS: We calculated visual field rates of progression using linear regression analysis of the Visual Field Index (VFI) for 100 consecutive patients with glaucoma having 10 or more Swedish Interactive Thresholding Algorithm ...
Kim Yong-Kyu - - 2009
PURPOSE: To analyze serial changes in retinal nerve fiber layer (RNFL) thickness after development of visual loss in patients with toxic optic neuropathy (TON) associated with antituberculosis pharmacotherapy, as well as to determine if RNFL changes correlate with clinical findings. METHODS: Five patients with TON underwent serial optical coherence tomography ...
Hirvonen Timo Petteri - - 2009
CONCLUSIONS: The nystagmus recorded without visual fixation contained all three components in most patients with vestibular neuritis (VN). The nystagmus was unidirectional, strongly visually suppressed with the loss of vertical component in most patients, and it obeyed Alexander's law. Video-oculography (VOG) is a non-invasive tool for detailed analysis of nystagmus, ...
Cronin Tara H - - 2009
To evaluate the feasibility of spectral domain optical coherence tomography (SD-OCT) macular scanning as a means of studying the afferent visual system in nystagmus patients. Nystagmus patients who underwent SD-OCT, clinical evaluation, and eye movement recordings were recruited for this prospective, single-center, noncomparative study. Three SD-OCT macular three-dimensional cube scans ...
Lim Ji Won - - 2010
PURPOSE: To investigate the clinical features of pegylated-interferon (PEG-IFN)-associated retinopathy in chronic hepatitis patients. METHODS: We examined a consecutive case series of 46 patients who were treated with PEG-IFN for chronic hepatitis C or B between October 2007 and September 2008. All patients underwent regular ophthalmologic examinations every 3 weeks ...
Patel Praveen J - - 2011
Objectives:  To determine the repeatability of Stratus optical coherence tomography fast macular thickness map analysis in patients with active neovascular age-related macular degeneration (nAMD). Methods:  Consecutive pairs of scans from 112 eyes of 112 consecutive patients with active nAMD were analyzed. The Bland-Altman coefficient of repeatability (CR) was calculated for ...
Demir M Necati - - 2009
PURPOSE: To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with chronic renal failure (CRF) without diabetes mellitus by using optical coherence tomography (OCT). METHODS: Sixty-six eyes of 33 patients with CRF were evaluated. Eighteen patients have been treated with hemodialysis (group 1) and 15 patients have been ...
Hamzaini A H - - 2009
Many patients who presented to Universiti Kebangsaan Malaysia Medical Centre (UKMMC) with signs and symptoms of urolithiasis had mild hydronephrosis with non visualization of calculus on ultrasound examination. These patients underwent an intravenous urogram (IVU) in order to determine the presence of urolithiasis and most of them had normal IVU. ...
Khan Aftab A - - 2009
OBJECTIVE: Hemangiomas are rare but highly vascular tumors that may develop in the cavernous sinus or orbit. These tumors pose diagnostic as well as therapeutic challenges to neurosurgeons during attempted removal. We analyzed our increasing experience using stereotactic radiosurgery (SRS). METHODS: Eight symptomatic patients with hemangiomas underwent SRS between 1988 ...
Kim Ei Tae - - 2009
BACKGROUND: To assess the nature, incidence, and risk factors of retinopathy associated with pegylated interferon and ribavirin combination therapy in chronic hepatitis C patients. METHODS: Thirty-two patients with chronic hepatitis C were examined prospectively for changes in fundus findings while they were being treated with pegylated interferon and ribavirin. Patients ...
Moroz Iris - - 2009
To evaluate the ability of optical coherence tomography (OCT) to predict the risk of retinal pigment epithelium (RPE) tear in patients with choroidal neovascular membrane associated with pigment epithelium detachment treated with bevacizumab. Retrospective observational case series of 24 consecutive patients treated with bevacizumab. All patients had sequential OCT scans ...
Gonzalez Pedro - - 2009
This study investigated the visual defects associated with the antiepileptic drug vigabatrin (VGB). Two hundred four people with epilepsy were grouped on the basis of antiepileptic drug therapy (current, previous, or no exposure to VGB). Groups were matched with respect to age, gender, and seizure frequency. All patients underwent objective ...
Tugal-Tutkun Ilknur - - 2009
Behçet's disease is a multisystem inflammatory disorder that is most common in countries along the ancient "Silk Road". The eye is the most commonly involved vital organ in Behçet's patients and the typical form of involvement is a relapsing remitting panuveitis and retinal vasculitis. Uveitis is the initial manifestation of ...
Symeonidis Chrysanthos - - 2011
Purpose:  We investigated the activity of matrix metalloproteinase (MMP)-2 and -9 and their latent pro-forms (proMMP-2, -9), and protein levels of MMP-1, -3, -8 and tissue inhibitor of MMPs (TIMP)-1 in the subretinal fluid (SRF) and vitreous of patients with rhegmatogenous retinal detachment (RRD). Potential correlations with proliferative vitreoretinopathy (PVR) ...
Ach Thomas - - 2010
To evaluate prognostic factors of response to intravitreal bevacizumab therapy of macular edema (ME) due to central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO). Patients with ME due to CRVO (32 patients) or BRVO (38 patients) received intravitreal bevacizumab (2.5 mg/0.1 ml) at baseline, and every 6 ...
Manrique Roslyn K - - 2009
BACKGROUND: Patients with spinocerebellar ataxia 7 (SCA7) are known to develop ocular abnormalities. The purpose of this study was to characterize these abnormalities in greater detail and with the aid of newer quantitative technologies. METHODS: Seven patients with SCA7 diagnosed by genetic analysis at La Paz Hospital (Madrid, Spain), a ...
Sugisaka Eiko - - 2010
PURPOSE: To investigate the visual sensations experienced by patients during vitrectomy under retrobulbar anesthesia. METHODS: 30 men and 45 women with a mean age of 65.3 +/- 10.6 years underwent vitrectomy under retrobulbar anesthesia for macular disease. 28 eyes had an idiopathic epiretinal membrane, 13 had an idiopathic macular hole, ...
Miller Randee C - - 2009
BACKGROUND: Spinocerebellar ataxia type 7 (SCA7) is a progressive ataxia that is unique among inherited ataxias in having a high prevalence of retinal photoreceptor abnormalities. However, the ophthalmic features and their relationship to the neurologic features of SCA7 have not been widely reported. The goal of this study was to ...
Thurtell Matthew J MJ Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH, - - 2009
Two patients with genetically confirmed spinocerebellar ataxia type 7 (SCA7) presented with progressive visual loss. Examination disclosed substantial visual acuity loss, central scotomas, and marked dyschromatopsia. Ophthalmoscopic abnormalities were subtle, with only mild retinal artery attenuation and minimal foveal region pigmentary abnormalities. Both patients had slow saccades and partially limited ...
Goodfellow Jonathan F B - - 2010
AIMS: To characterize photopsia in posterior vitreous detachment (PVD), retinal tears (RT) and rhegmatogenous retinal detachment (RRD). METHODS: Seventy seven patients presenting to an eye emergency department and vitreoretinal clinic with photopsia had documentation of their symptoms. RESULTS: A total of 27 patients had PVD alone, 7 had RTs and ...
Reinhard Jens - - 2010
BACKGROUND: After full macular translocation (MT) surgery with 360 degrees retinotomy, the fovea is rarely identifiable. Our aim was to verify the position of the fovea, to determine how patients fixate after MT and to examine distribution and optical density of macular pigment (MP). METHODS: 9 patients after MT were ...
Al-Muhsen Saleh - - 2009
INTRODUCTION: Chronic granulomatous disease (CGD) is a primary immunodeficiency disease caused by a genetic defect in the NADPH oxidase complex of phagocytic cells. Recent reports indicate that chorioretinal lesions are more common than previously suspected. In this study, ocular findings of CGD patients are described with particular emphasis on chorioretinal ...
Kunavisarut Paradee - - 2009
PURPOSE: To determine clinical features of patients with severe chronic central serous chorioretinopathy (diffuse retinal pigment epitheliopathy, DRPE) associated with bullous retinal detachment in Thailand. METHODS: The authors reviewed clinical and imaging characteristics, visual outcomes, and complications of 7 patients with severe DRPE associated with bullous retinal detachment. RESULTS: Included ...
Memon Ameer Ahmed - - 2009
OBJECTIVE: To assess the visual outcome and complications after removal of posterior segment retained intraocular foreign bodies through pars plana approach. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Department of Ophthalmology, Jinnah Postgraduate Medical Centre, Karachi, from May 2005 to May 2006. METHODOLOGY: Fifty patients with history of ...
Mohamed Maha M - - 2009
To detect early glaucomatous changes in pseudo exfoliative patients with normal intraocular pressure (IOP), visual field and optic nerve head appearance; by measuring retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT). A prospective observational case-control study. Twenty non-glaucomatous (normal IOP, fundus and visual field) pseudo exfoliative patients ...
Czoski-Murray Carolyn C University of Sheffield, Sheffield, UK. - - 2009
This article reports on a study that used contact lenses to simulate the effects of a visual impairment caused by age-related macular degeneration (ARMD). The primary objective was to examine the feasibility of using this method of simulation. A secondary objective was to compare the results from this experiment with ...
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