Search Results
Results 351 - 400 of 995
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Castillo A R G L - - 2005
OBJECTIVE: To evaluate the patterns of regional cerebral blood flow (rCBF) in cortical and subcortical regions by Brain SPECT imaging, in children and adolescents with obsessive-compulsive disorder (OCD) before and after treatment. METHOD: Fourteen OCD patients (6 to 17 years old) underwent brain SPECT; ten of those subjects were reexamined ...
Treccani Barbara - - 2005
The judgement of line orientation test (JLOT) is widely used to assess visuo-spatial processing. Most neuropsychological studies have shown that on this task right hemisphere damaged (RHD) patients are significantly more impaired than left hemisphere damaged (LHD) patients, suggesting a dominant role of the right hemisphere in discriminating line orientation. ...
Lo Steven E - - 2005
INTRODUCTION: Primary cervical and oromandibular dystonia (CD and OMD, respectively) are well-recognized movement disorders, often treated with botulinum toxin (BTx). In contrast, dystonia related to acute brain injuries is not well delineated. Our objective was to define in neurocritically ill patients the clinical characteristics of CD and OMD and to ...
Yatham Lakshmi N - - 2005
OBJECTIVE: To examine the effects of treatment with valproate on brain 5-HT2A receptors in acute manic patients using positron emission tomography (PET) and [18F]-setoperone. METHODS: Patients with DSM-IV bipolar I disorder-manic episode were recruited. Patients were drug free or drug naïve at the time of baseline PET scan. All patients ...
Lindén A - - 2005
OBJECTIVE: To compare recovery of cognitive functions and activities of daily living during the first year of rehabilitation after severe brain trauma. METHODS: Sixteen patients were evaluated by neuropsychological tests and occupational performance (assessment of motor and process skills, AMPS) on admission to the rehabilitation centre and 3, 6 and ...
Samadani U - - 2005
Despite growing recognition among those who provide care for traumatic brain injury patients, endocrine dysfunction following brain injury is an often under-recognized phenomenon. From historical reports one would conclude that endocrine dysfunctions hardly ever occurs following trauma to the head. However, recent studies suggest that a significant proportion of patients ...
Palmer Sylvain - - 2005
INTRODUCTION: The value of brain tissue oxygenation (PbtO2) measurements in determining brain death is unknown. METHODS: Eleven of 72 patients who had brain tissue oxygen monitors placed experienced brain death. Admission diagnoses included six severe traumatic brain injuries, one multiple trauma with cardiac arrest, one brain tumor, one subarachnoid hemorrhage, ...
Magalhaes Alvaro - - 2005
RATIONALE AND OBJECTIVES: Evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for assessing and grading brain tumors. MATERIALS AND METHODS: The research was done at Detroit Medical Center in a 1.5-T Siemens MR magnet using single-voxel or multivoxel MRS. This study consisted of 27 patients: 10 females and 17 males ages 22-83 ...
Iverson Grant L GL Department of Psychiatry, University of British Columbia and Riverview Hospital, Vancouver, BC, Canada. - - 2005
Patients involved in litigation relating to mild traumatic brain injury (MTBI) typically undergo a forensic neuropsychological evaluation. However, if cognitive problems are identified, it is difficult to know whether these are related to the MTBI or other factors such as pre- and/or post-injury substance abuse. The purpose of this study ...
Dolberg Ornah T - - 2005
Topiramate is an antiepileptic drug known to have effects on weight. In order to use this as a tool to treat eating disorders, it is useful to examine whether these effects can be predicted in certain patients. To report the effects of topiramate, initiated for the treatment of epilepsy, on ...
Burkhard P R - - 2004
The authors observed a high rate of suicide (6/140 patients, 4.3%) in a large cohort of patients with movement disorders treated with deep brain stimulation (DBS). Apparent risk factors included a previous history of severe depression and multiple successive DBS surgeries, whereas there was no relationship with the underlying condition, ...
Richard Christelle - - 2004
The egocentric reference appears to be altered in neglect patients, as evidenced by an ipsilesional error when pointing straight ahead. In this study, patients with right brain damage used a horizontal rod to show this straight-ahead direction. There was a systematic rightward translation of the rod, and no clockwise rotation ...
Agha Amar - - 2004
Disorders of water balance are well recognized after traumatic brain injury (TBI), but there are no reliable data on their true prevalence in post-TBI patients. We aimed to evaluate the prevalence of posterior pituitary dysfunction in a large cohort of survivors of TBI. One hundred two consecutive patients (85 males) ...
Yohena Tomofumi - - 2004
BACKGROUND: The exclusion of brain metastasis is important to determine the optimal treatment plan in patients with non-small cell lung cancer (NSCLC). However, a routine examination using magnetic resonance imaging (MRI) for the brain remains controversial in preoperative patients with resectable disease. METHODS: To assess the necessity of routine brain ...
Mirzaa G - - 2004
BACKGROUND AND OBJECTIVE: Megalencephaly (MEG) or enlarged brain occurs as a mild familial variant with normal brain structure, but otherwise is an uncommon human brain malformation that may be associated with significant developmental and neurological problems. It has been classified into anatomic and metabolic subtypes. The clinical findings associated with ...
Maron Eduard - - 2004
The purpose of this study was to characterize the binding properties of serotonin transporter (5-HTT) in the brain of the patients with generalized anxiety disorder (GAD) in comparison to healthy subjects using single photon emission computer tomography (SPECT) with the radioligand [123I]nor-beta-CIT. The subjects were 7 patients with GAD and ...
Shiotani S - - 2004
The aim of this study was to clarify the role of serum S100 beta on the accurate assessment of reversibility of brain damage after fulminant hepatic failure (FHF). Among the 13 patients with FHF enrolled in this study, 12 underwent living donor liver transplantation; one patient could not the procedure ...
Neumann Nicola - - 2004
A systematic neuropsychological assessment technique is described for use with severely physically disabled individuals, possibly with combined motor and cognitive disorders. Target neurological conditions may be, e.g., an incomplete locked-in state, a minimally conscious state, or severe combinations of paralysis, agnosia, and apraxia. Neuropsychological assessment in these patients is difficult, ...
Möller M - - 2005
In patients with brain lesions adjacent to the central area, exact preoperative knowledge of the spatial relation of the tumour to the motor cortex is of major importance. Many studies have shown that functional magnetic resonance imaging (fMRI) is a reliable tool to identify the motor cortex. However, fMRI data ...
Sakho, Youssoupha; Service de ...
Background and purpose: Neurosurgeons face a lot of pitfalls while dealing with brain tuberculomas. Our purpose is to set an algorithm . Methods: From 1996 to 2001 ,the authors reported 4 patients harbouring brain tuberculomas who have been hospitalised at our neurosurgical department .Medical reports of theses 4 patients were ...
Castriota-Scanderbeg A - - 2004
In an attempt to clarify whether T1 relaxation time mapping may assist in characterizing the pathological brain tissue substrate of multiple sclerosis (MS), we compared the T1 relaxation times of lesions, areas of normal-appearing white matter (NAWM) located proximal to lesions, and areas of NAWM located distant from lesions in ...
Nybo Taina - - 2004
We studied how moderate to severe childhood traumatic brain injury (TBI) affects vocational outcome with time. This is the second follow-up of patients who were injured as preschoolers in traffic accidents. In the first follow-up the mean age was 23 years and in the present study the average age of ...
Filippi Massimo - - 2004
BACKGROUND: Magnetization transfer magnetic resonance imaging (MT MRI) can provide in vivo markers reflecting the severity of multiple sclerosis-related brain damage occurring within and outside T2-visible lesions. OBJECTIVE: To investigate the effect of intravenous immunoglobulin (IVIG) treatment on the accumulation of brain damage in patients with secondary progressive multiple sclerosis ...
Bigler Erin D - - 2004
Autopsy studies were undertaken in a 47-year-old college-educated male patient who, 7 months prior to an unexpected death, had sustained a mild traumatic brain injury (TBI) as manifested by brief loss of consciousness and an initial Glasgow Coma Scale score of 14. The patient died from cardiac arrest secondary to ...
Pachalska Maria - - 2004
Background. The purpose of this study was to characterize the speech and language disturbances seen in patients with traumatic brain injury aroused from long-term coma at the Rehabilitation Clinic of the Bydgoszcz Academy of Medicine. Material and methods. The research covered 94 patients (30 women, 64 men, average age 34.7). ...
Yew David T - - 2004
Using immunohistochemistry, Fas and caspase 8 positive sites were localized in the brains of Alzheimer patients and those with multiple infarcts as well as age-matched normal. The frontal, occipital and hippocampal regions were dissected out from these patients and normal individuals shortly after death. Positive Fas neurons were found in ...
Lindström Mats B - - 2004
Altered monoaminergic activity has earlier been associated with violent suicidal behaviour. In this study whole brain binding potential of the serotonin transporter (5HTT) and dopamine transporter (DAT) was measured by single photon emission computerised tomography (SPECT) in 12 patients after a serious suicide attempt and in 12 age, sex and ...
Demirören Kaan - - 2004
BACKGROUND: The objective of this study was to determine whether technetium-99m hexamethyl-propyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT) imaging is capable of detecting perfusional abnormalities in Sydenham's chorea (SC) patients and contributing to diagnosis of SC. METHODS: In this study, 17 SC patients were evaluated. HMPAO SPECT ...
Constantoyannis Constantine - - 2004
BACKGROUND: Deep brain stimulation (DBS) is increasingly used to treat a variety of neurological conditions (e.g. movement disorders and chronic pain). This prospective study was designed to detect electrocardiogram (ECG) artifacts induced by deep brain stimulation and to investigate which factors (patient disease, electrode position within the brain or type ...
Sinha Sanjeev - - 2004
OBJECTIVE: To evaluate brain metabolism and cerebral blood flow in young patients with hyperlipidaemia. PATIENTS AND METHODS: Proton magnetic resonance spectroscopy ((1)H MRS) and single photon emission computed tomography (SPECT) of the brain was carried out in 19 asymptomatic young patients with hyperlipidaemia (mean age 32.6 +/- 6.0 years, range ...
Meyers John E - - 2004
This manuscript reports the results of two studies focusing on patients with mild Traumatic Brain Injury (TBI). The first assesses the validity of the Meyers Short Battery (MSB) of neuropsychological tests. The second study reports on the reliability of the MSB. The groups consisted of normal controls, depressed, chronic pain ...
Harmsen M M Department of Rehabilitation Medicine, St. Maartenskliniek, Nijmegen, The - - 2004
To investigate the association of post-traumatic amnesia (PTA) with positive behavioural disturbances (PBD) in an historic cohort of patients with severe traumatic brain injury (TBI) and to evaluate the use and effects of neuroleptic drugs in this cohort. Historic cohort study. The medical files of 60 patients with severe TBI, ...
Kim Ji Hye - - 2004
OBJECTIVE: The purpose of our study was to describe acute necrotizing encephalopathy in Korean infants and children, and we sought to evaluate the prognostic factors. MATERIALS AND METHODS: Acute necrotizing encephalopathy was diagnosed in 14 Korean infants and children. We retrospectively analyzed the neuroimaging findings including the follow-up changes. The ...
Fàbregas Neus - - 2004
BACKGROUND: The probability of recovering consciousness in acute brain-injured patients depends on central nervous system damage and complications acquired during their stay in the intensive care unit. The objective of this study was to establish a relation between the Bispectral Index (BIS) and other variables derived from the analysis of ...
Prigatano George P GP Division of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA. - - 2004
Eight healthy volunteers and seven post-acute patients with a history of severe traumatic brain injury (TBI) performed the Halstead Finger Tapping Test while undergoing functional magnetic resonance imaging (fMRI). Patients with TBI were on average 18.5 years post-trauma and at that time had normal or near normal tapping speeds. The ...
Llompart Pou Juan Antonio - - 2004
OBJECTIVE: Transcranial color-coded duplex sonography (TCCDS) is a non invasive bedside technique that allows the determination of midline shift (MLS). The purpose of our study was to compare MLS measurements using TCCDS with those obtained with cranial computerized tomography (CT) in patients with traumatic brain injury (TBI). DESIGN: Prospective study. ...
Frucht Steven J - - 2004
Posthypoxic myoclonus (PHM) is a syndrome of action and intention myoclonus that occurs in some patients who survive a cardiac arrest. Using PET and statistical parametric mapping, the authors observed a significant bilateral increase in glucose metabolism in the ventrolateral thalamus and pontine tegmentum in patients relative to controls. Interventions ...
Yianni J - - 2004
Deep brain stimulation (DBS) therapy is a continually expanding field in the functional neurosurgical treatment of movement disorders. However, the occurrence of adverse events related to implanted hardware cannot be overlooked. We report on a specific feature noted in our experience of DBS-related complications. From 1998 until present we have ...
Ariza Mar - - 2004
BACKGROUND: Proton magnetic resonance spectroscopy can assess neurochemical sequelae in traumatic brain injury. Metabolic abnormalities are present in the acute or subacute period in patients with traumatic brain injury and correlate with outcome on clinical scales. OBJECTIVE: To investigate the use of proton magnetic resonance spectroscopy in detecting possible gray ...
Kaleita Thomas A - - 2004
PURPOSE: To determine the relative contributions of patient, disease and therapy specific factors on neurocognitive outcome of brain tumor patients. PATIENTS AND METHODS: Seventy-nine patients (mean age = 41.1 years; range: 17-75 years; 54% male, 46% female) with glioblastoma multiforme (37%), anaplastic astrocytoma (17%), low grade astrocytoma (13%), and oligodendroglioma ...
Boly Mélanie - - 2004
BACKGROUND: The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative state (PVS) by the presence of inconsistent, but clearly discernible, behavioral evidence of consciousness. OBJECTIVE: To study auditory processing among patients who are in an MCS, patients who are in a PVS, ...
Mazzini Letizia - - 2004
ERPs may extend the battery of neurophysiologic tests currently available for determining the functional integrity of the central nervous system and the capacity of cognition in patients with brain injury. The use of stimuli relevant for the patient can enhance the probability to record these waves in unconscious patients and ...
Shah Mrugeshkumar K MK Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital, Harvard Medical Schol, Boston, Massachusetts, USA. - - 2004
To compare the functional outcomes of patients with anoxic brain injury (ABI) and patients with traumatic brain injury (TBI) following inpatient rehabilitation. Retrospective chart review. Data on 68 patients with brain injury (34 with ABI and 34 with TBI) were collected. The ABI and TBI groups were demographically similar, except ...
Gallo A - - 2004
This is a multiparametric MR study of the first reported patient with adult-onset genetically confirmed vanishing white matter (VWM) disease. It shows that, despite the presence of a severe and diffuse damage of the brain WM, brain gray matter, and cervical cord tissue, the cortical adaptive capacities were relatively preserved. ...
Agazzi S - - 2004
BACKGROUND: In patients presenting brain metastases as the first manifestation of a previously undiagnosed primary tumour (UDP) histopathological confirmation of the diagnosis can be obtained by either direct surgical sampling of the brain lesion or paraclinical search for an accessible primary tumour. The sequence of the diagnostic work-up and the ...
Schoenle Paul W - - 2004
Event-related potentials (ERPs) can provide valuable information about cognitive capabilities in severely brain-damaged patients. This study examined 120 patients with severe brain damage using event related potentials ERPs (N 400) to gain information about their remaining semantic processing capabilities and to contribute to differential diagnosis. Patients were classified into three ...
Sun S S - - 2004
Methylprednisolone pulse therapy (MPT) was introduced to avoid life-threatening complications in patients with systemic lupus erythematosus (SLE) with brain manifestations; however, the efficacy of MPT in SLE patients with brain involvement is still uncertain and needs to be objectively evaluated. We enrolled 15 female SLE patients with neuropsychiatric manifestations in ...
Kress Thomas - - 2003
Event-related brain potentials (ERPs) to faces have been shown to be altered in patients suffering from prosopagnosia. In this report we present ERP findings from two patients suffering from a congenital form of prosopagnosia, with other visual and cognitive functions being spared and without any structural abnormalities as assessed by ...
Sassi Roberto B - - 2003
BACKGROUND: Increased rates of white matter hyperintense lesions have been reported in mood disorder patients. However, the potential effects of age and illness severity on reported findings are not fully established. We examined the rates of hyperintense lesions in adult, non-elderly bipolar and unipolar patients, with a relatively mild-to-moderate illness ...
Kotz Sonja A - - 2003
The role of the basal ganglia in syntactic language processing was investigated with event-related brain potentials in fourteen neurologically impaired patients. Seven of these patients had basal ganglia lesions while 7 other patients primarily had lesions of the left temporo-parietal region excluding the basal ganglia. All patients listened to sentences ...
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