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Zou Hui H Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. - - 2014
Epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), the AA and BB isoforms of platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) are involved in the pathogenesis of airway inflammation in asthma. In the present study, the associations between asthmatic phenotypes and the expression levels of these ...
de Oliveira Manoel Airton Leonardo AL Trauma & Neurosurgical Intensive Care Unit, St. Michael's Hospital-University of Toronto, 30 Bond Street Donnelly Wing, Room 3-074B, Toronto, ON, M4N 3M5, Canada, - - 2014
The presence of coagulopathy is common after severe trauma. The aim of this study was to identify whether isolated severe traumatic brain injury (TBI) is an independent risk factor for coagulopathy. Prospective observational cohort of adult patients admitted to a Level I Trauma Center within 6 h of injury. Patients were ...
Samai Alyana A From the Stroke Program, Department of Neurology (A. Samai, D.M., A. Shaban, A.G., L.D., L.S., R.E.K., S.M.-S.) and Section of Hematology/Oncology, Department of Medicine (R.K.-J.) Tulane University School of Medicine, New Orleans, LA; and Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, LA (A. - - 2014
Despite clear roles of factor VIII (FVIII) and von Willebrand factor (vWF) in thrombosis, few studies have examined the relationship of these factors with acute ischemic stroke (AIS). We sought to determine whether concurrent elevation in FVIII and vWF was associated with adverse events and outcomes. From our prospective stroke ...
Horstmann S S Department of Neurology, University of Heidelberg, Heidelberg, - - 2014
Cognitive deficits are common following stroke. Cognitive function in the acute stroke setting is a predictive factor for mid-term outcome. The Montreal Cognitive Assessment (MoCA) is a screening tool for cognitive impairment. The feasibility of MoCA in the acute phase of stroke was evaluated and factors predictive of cognitive impairment ...
Cao Liping L Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing 210002, - - 2014
As an inducible isoform of heme oxygenase (HO), HO-1 was suggested to have an anti-oxidative stress, anti-inflammatory, anti-apoptotic and anti-proliferative effect. It was regarded as an important cytoprotective enzyme. We undertook this study to investigate whether HO-1 gene rs2071746 polymorphism was associated with clinical outcomes in atherosclerosis ischemic stroke patients. ...
Ye Hongjian H Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, 58th, Zhongshan Road II, Guangzhou, 510080, - - 2014
The study was to investigate the prevalence and associated factors of erectile dysfunction (ED) in peritoneal dialysis (PD) patients. This was a cross-sectional survey. Eligible patients were interviewed by questionnaire: the five-item version of International Index of Erectile Function. Residual renal function (RRF) was assessed by daily urine volume and ...
Fernández-Yunquera Ainhoa A Ainhoa Fernández-Yunquera, Cristina Ripoll, Rafael Bañares, Diego Rincón, Ismael Yepes, Vega Catalina, Magdalena Salcedo, Department of Liver Transplantation, Hospital General Gregorio Marañón, 28028 Madrid, - - 2014
To evaluate the expression of serum fibrosis markers in liver transplantation (LT) recipients on everolimus monotherapy compared to patients on an anti-calcineurin regimen. This cross-sectional case-control study included LT patients on everolimus monotherapy (cases) (E) (n = 30) and matched controls on an anti-calcineurin regimen (calcineurin inhibitors, CNI), paired by ...
Paret Nathalie N Centre régional de pharmacovigilance, 162, avenue Lacassagne, 69003 Lyon, - - 2014
A decrease in factor V activity has been reported in some patients treated with azathioprine or 6-mercaptopurine. This may lead to unnecessary treatment discontinuation in otherwise asymptomatic patients. Our aim was to review spontaneously reported cases of decreased factor V activity associated with both drugs and to identify the possible ...
Mao Youying Y Nephrology and Rheumatology Department, Shanghai Children's Medical Centre, School of Medicine, Shanghai Jiao Tong University, Shanghai, - - 2014
To analyse the clinical features of Henoch-Schönlein purpura (HSP) with or without nephritis in Chinese children and to determine the risk factors for renal involvement. Patient characteristics, clinical parameters and laboratory data were retrospectively analysed in patients with HSP with or without nephritis. Logistic regression analysis was used to identify ...
Zhang Ye Y Department of Chemotherapy, The Affiliated Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing, Jiangsu 210009, P.R. - - 2014
The aim of the present study was to evaluate the clinical significance and prognostic value of growth‑regulated oncogene‑1 (GRO‑1), hepatocyte growth factor (HGF), platelet‑derived growth factor‑AA (PDGF‑AA), soluble E‑selectin (sE‑selectin) and high‑risk human papillomavirus (HPV; types 16, 18/45, 31 and 33/52/58/67) infection in cervical squamous cell carcinoma (CSCC). A total ...
Koami Hiroyuki H Department of Surgery, Center for Gastroenterology, Urasoe General Hospital, Iso 4-16-1, Urasoe, 901-2132, Japan, - - 2014
To evaluate the risk factors for bowel necrosis in adult patients with hepatic portal venous gas (HPVG). This retrospective study comprised 33 adult patients treated for HPVG between August, 2008 and December, 2011. The patients were divided into a necrotic group (n = 14) and a non-necrotic group (n = 19). We analyzed the ...
AlEnezi Husein H King Saud University, Riyadh, Saudi - - 2014
A decline in semen quality in men with increasing percentage of male factor abnormalities in infertile couples has been reported. The pattern of abnormalities differs from one part of the world to another, and it is probably multifactorial. Our objectives were to review the pattern of semen fluid abnormalities in ...
Upadhyaya Suneet Kumar SK Department of Psychiatry, Gujarat Medical Education and Research Society Medical College, Patan, Gujarat, - - 2014
A better understanding of risk factors associated with postpartum psychosis may contribute to the better management. This study was to identify the risk factors contributing to postpartum psychosis. In this cross-sectional, case control study 100 patients of postpartum psychosis (PP) were compared with the healthy controls. Risk factors explored were ...
Lee Myung Won MW Division of Endocrinology, Department of Internal Medicine, Institute of Endocrine Research, Yonsei University College of Medicine, Seoul, - - 2014
Patients with subclinical hypothyroidism (SHT) are common in clinical practice. However, the clinical significance of SHT, including prognosis, has not been established. Further clarifying SHT will be critical in devising a management plan and treatment guidelines for SHT patients. Thus, the aim of this study was to investigate the prognostic ...
Seners Pierre P From the INSERM UMR S894, Université Paris Descartes, Sorbonne Paris Cité, Paris, France (P.S., G.T., M.T., L.L., M.-A.L., D.C., J.-F.M., J.-L.M., C.O., J.-C.B.); and Service de Neurologie (P.S., G.T., D.C., J.-L.M., J.-C.B.) and Service de Neuroradiologie (M.T., L.L., M.-A.L., J.-F.M., C.O.), Centre Hospitalier Sainte-Anne, Paris, - - 2014
Early neurological deterioration (END) after anterior circulation stroke is a serious clinical event strongly associated with poor outcome. Regarding specifically END occurring within 24 hours of intravenous recombinant tissue-type plasminogen activator, apart from definite causes such as symptomatic intracranial hemorrhage and malignant edema whose incidence, predictors, and clinical management are ...
De Santis Gil Cunha GC Universidade de São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: - - 2014
Rupture of the spleen can be classified as spontaneous, traumatic, or pathologic. Pathologic rupture has been reported in infectious diseases such as infectious mononucleosis, and hematologic malignancies such as acute and chronic leukemias. Splenomegaly is considered the most relevant factor that predisposes to splenic rupture. A 66-year-old man with acute ...
Criado Paulo Ricardo PR University of São Paulo, São Paulo, - - 2014
Chronic venous disease affects millions of people around the world. Venous valvular incompetencies and venous reflux, often a result of outflow obstruction are important contributors to venous disease. The prevalence of thrombophilia is increased in patients with chronic venous insufficiency (CVI). The recognition of underlying thrombophilia particularly in young patients ...
Yu Shu-Yang - - 2014
Cognitive impairment strikingly reduces the quality of life of Parkinson's disease (PD) patients. Studies find that pathological proteins, neuroinflammatory factors and free radicals may involve in the pathogenesis of cognitive impairment of PD, however, results are inconclusive. We recruited 62 PD patients and 31 healthy controls. PD patients were identified ...
Christov Marta M aDivision of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center bDivision of Endocrinology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, - - 2014
To review the emerging literature on changes in fibroblast growth factor 23 (FGF23) levels in the setting of acute kidney injury (AKI). Studies suggest that FGF23 levels are elevated in patients with AKI and correlate with increased risk of death or need for dialysis in adults, or prolonged ventilation time ...
Halperin Jonathan L - - 2014
Patients with non-valvular atrial fibrillation (AF) face an increased risk of stroke compared with those in normal sinus rhythm. The vitamin K antagonist warfarin, available for over half a century, is highly effective in reducing the risk of stroke in patients with AF, but it is a difficult drug to ...
Kutcher Matthew E ME Department of Surgery, San Francisco General Hospital, CA; and the University of California at San - - 2014
To investigate the natural history of coagulation factor perturbation after injury and identify longitudinal differences in clotting factor repletion by RBC:FFP (red blood cell:fresh frozen plasma) transfusion ratio. Hemostatic transfusion ratios of RBC to FFP approaching 1:1 are associated with a survival advantage in traumatic hemorrhage, even in patients with ...
Afaf Houb-Dine HD Service d'Orthopédie Dento-Faciale, Faculté de Médecine Dentaire de Rabat, Université Mohamed V Souissi, Rabat, Morocco. Electronic address: - - 2014
Extraction of two upper premolars in Class II division 1 occlusions often constitutes a therapeutic compromise for the orthodontic practitioner. The aim of our study was to compare the initial occlusal and cephalometric severity of Class II division 1 malocclusions in two groups of patients treated with and without extraction ...
Yoneno Kazuaki K Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, - - 2014
Background and Aims: Infliximab (IFX) is a monoclonal antibody used to treat patients with Crohn's disease (CD). Intra-abdominal abscess formation is a major complication of CD with negative effects on patient prognosis. We have analyzed risk factors for abscess formation in CD patients treated with IFX. Methods: CD patients who ...
Zhao Jg J Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, - - 2014
Abstract This study assessed the risk factors associated with mortality and the development of intra-abdominal hypertension (IAH) in patients with severe acute pancreatitis (SAP). To identify significant risk factors, we assessed the following variables in 102 patients with SAP: age, gender, etiology, serum amylase level, white blood cell (WBC) count, ...
Ito Yasuhiro Y Department of Surgery, Saiseikai Yokohamashi Tobu Hospital, Kanagawa, - - 2014
Patients who undergo pancreaticoduodenectomy (PD) are at risk of steatosis because resection of the pancreatic head causes pancreatic exocrine and endocrine insufficiency. We investigated the clinicopathological features and the risk factors of nonalcoholic fatty liver disease (NAFLD) after PD. This was a retrospective study of 100 patients who underwent PD ...
Bucurescu S S "Rhoen Klinikum AG" Hospital, 97616 Bad Neustadt ad Saale, - - 2014
In this paper, we describe the case of recurrent cerebral venous sinus thrombosis in a patient with increased factor VIII activity, lipoprotein (a) level, and leukocytosis. In addition, we discuss the diagnosis of increased factor VIII activity in patients with cerebral venous thrombosis. With regard to therapy, studies need to ...
Haro Hirotaka H Department of Orthopaedic Surgery, Graduate School of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan, - - 2014
Lumbar herniated discs commonly occur in patients 20-40 years of age, and result in acute symptoms of shooting and intractable pain in the low back and/or lower extremities. However, the prognosis of these patients is considered to be very good. Moreover, 70 % of these patients have been reported to be free ...
Patel Divyang D University of Pittsburgh School of Medicine, Pittsburgh, - - 2014
QT interval prolongation in patients with end-stage liver disease (ESLD) is common. However, electrolyte abnormalities, renal insufficiency, treatment with QT-prolonging drugs, and other factors known to prolong QT interval independently of liver disease occur frequently in ESLD. Moreover, elevated heart rate may be present in ESLD and result in spurious ...
Okazaki Hideto H Department of Rehabilitation Medicine II, School of Medicine, Fujita Health University, Tsu Mie, Japan. Electronic address: - - 2014
Predicting recovery from hemiparesis after stroke is important for rehabilitation. A few recent studies reported that the levels of some growth factors shortly after stroke were positively correlated with the clinical outcomes during the chronic phase. The aim of this study was to examine the relationships between the serum levels ...
Juratli Tareq A TA University Hospital Dresden, Department of Neurosurgery, Fetscherstrasse 74, Dresden, Deutschland, Germany, 01307, 493514584909 ; - - 2014
The focus of this paper is to identify and quantify risk factors for early hemorrhagic progression of brain contusions (HPC) in patients with traumatic brain injuries (TBI) and to evaluate their impact on patients' outcome. Further, based on abnormal values in routine blood tests, the role of trauma induced coagulopathy ...
Sølvik Una Ø UO Department of Global Public Health and Primary Care, University of Bergen , - - 2014
Background. Biological variation is usually estimated in healthy individuals during steady-state conditions. The aim of this study was to estimate the in-treatment biological variation of the International normalised ratio (INR) and to investigate to what extent the different levels of coagulation factors could explain this variation. Methods. Blood samples were ...
Yoo Byung Won BW Department of Clinical Pharmacology, Clinical Trial Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of - - 2014
Congestive hepatopathy after a Fontan operation can have a major effect on long-term morbidity. We evaluated congestive hepatopathy in patients with Fontan circulation using transient elastography to determine which risk factors for hepatopathy are related to liver stiffness (LS). We evaluated 46 patients with Fontan circulation and 26 with right side ...
Pasala Sanjiv S University of Arkansas for Medical Sciences College of Medicine, Arkansas Children's Hospital, Little Rock, Arkansas Department of Pediatrics, Divisions of Pediatric Critical Care*, Pediatric Hematology and Oncology†, Pediatric - - 2014
Acquired von Willebrand Factor (vWF) disease is associated with a decrease in the amount of circulating high molecular weight (HMW) vWF multimers. vWF has not been previously investigated in children on ECMO support.We hypothesized that HMW vWF multimers and vWF activity decrease over the course of ECMO support in these ...
Alkaabi Juma K JK Rheumatology Unit, Department of Medicine, Sultan Qaboos University Hospital, Muscat, - - 2014
This study aimed to evaluate the cause of thrombosis in Behçet's disease (BD) patients, since abnormalities in coagulation and fibrinolytic parameters have shown contradictory results. Haemostatic parameters were retrospectively evaluated in BD patients treated between January 2007 and January 2011 at Sultan Qaboos University Hospital, Oman. The blood samples of ...
Ohman M M Institution of Medicine and Public Health/Rheumatology, University of Umeå , - - 2014
Objectives: Patients with rheumatoid arthritis (RA) have increased mortality and morbidity due to cardiovascular disease (CVD). A high apolipoprotein (apo)B/apoA1 ratio is known to predict cardiovascular events (CVEs) in the population. apoA1 has, besides anti-atherogenic effects, anti-inflammatory properties. The importance of apolipoproteins in the development of CVEs, in the context ...
Hernández Garcés Héctor Ruben HR Institute of Gastroenterology. La Habana, - - 2014
Context: Acute pancreatitis is the most common complication in ERCP, and some risk factors were associated with the development of hyperamylasemia and post-ERCP pancreatitis. Objectives: identifying new factors associated with the development of hyperamylasemia or post-ERCP pancreatitis in patients attended at our center. Material and methods: A (retrospective) cohort study ...
Wormer Blair A BA Carolinas Medical Center, Charlotte, NC, - - 2014
The objective of this study was to perform a national review of patients with acute pancreatitis (AP) who undergo pancreatic debridement (PD) to evaluate for risk factors of in-hospital mortality. The Nationwide Inpatient Sample was used to identify patients with AP who underwent PD between 1998 and 2010. Risk factors ...
Talaat Roba M RM Molecular Biology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), Sadat City University, Sadat City, - - 2014
Hepatocellular carcinoma (HCC) is a hypervascular tumor characterized by neovascularization. The objective of the current study was to determine circulating proangiogenic [vascular endothelial growth factor (VEGF), platelet derived growth factor (PDGF), and tumor necrosis factor (TNF-α)] and antiangiogenic [IL-4, IL-12, interferon gamma-induced protein 10 (IP-10), and angiostatin] factors in Egyptian ...
Zotter Zsuzsanna - - 2014
Hereditary angioedema (HAE) resulting from C1-inhibitor deficiency is characterized by attacks of subcutaneous and submucosal edema. Many factors have been presumed to induce edema. Our study analyzed these factors in a fairly large patient population. In the first stage of our study, we analyzed the data recorded by 92 subjects ...
Arestedt Kristofer K 1Department of Medical and Health Sciences, Division of Nursing Science, Linköping University, Linköping, - - 2014
Background:The four-item Control Attitudes Scale (CAS) was developed to measure control perceived by patients with cardiac disease and their family members, but extensive psychometric evaluation has not been performed.Objective:The aim was to translate, culturally adapt and psychometrically evaluate the CAS in a Swedish sample of implantable cardioverter defibrillator (ICD) recipients, ...
Yu Hai H From the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, - - 2014
We investigated the predictors and outcomes of aneurysmal subarachnoid hemorrhage in patients with shunt-dependent hydrocephalus and make a preliminary inquiry into the relationship between the two. A consecutive cohort of 202 patients was evaluated, which included 40 shunt-dependent hydrocephalus patients. The basic characteristics on admission, complications of hemorrhage, management before ...
Bruins Slot Karsten M H KM Department of Internal Medicine, Oslo University Hospital, Oslo, - - 2014
Is treatment with factor Xa inhibitors associated with better efficacy and safety compared with the vitamin K antagonist warfarin for preventing strokes or other systemic embolic events in patients with atrial fibrillation? Compared with warfarin, factor Xa inhibitors are associated with a lower risk of stroke and other systemic embolic ...
Thorell S E SE School of Medicine, University of Manchester, Manchester, - - 2014
Coagulation screens are performed routinely in every hospital with the notion that an abnormal result will pick up low levels of coagulation factors and thus aid in determining patients' bleeding risk. We analysed all the clotting factor assays performed for abnormal clotting screen in a tertiary hospital over a 1-year ...
Qian Cheng C Department of Neurosurgery, Oulu University Hospital, Oulu, Finland. Electronic address: - - 2014
Seizures after primary intracerebral hemorrhage (PICH) are significant and treatable complications, but the factors predicting immediate, early and late seizures are poorly known. We investigated characteristics and outcome with special reference to occurrence and timing of a first seizure among consecutive subjects with PICH. A population-based study was conducted in ...
Kwaan Hau C HC Division of Hematology/Oncology, Olson Pavilion, Chicago, - - 2014
The hemostatic abnormalities seen in acute promyelocytic leukemia (APL) are unique and account for much of the morbidity and mortality of this disorder. Almost all patients present at diagnosis with laboratory findings of intravascular coagulation along with increased fibrinolysis. This unusual combination is correlated to the clinical manifestations with high ...
Abbas Zaigham Z Department of Medicine, Aga Khan University, Karachi, - - 2014
Background/Aim: We aimed to assess the influence of Helicobacter pylori and its virulent factors, cytotoxin associated gene (cag) A and E, on portal hypertensive gastropathy (PHG) and the levels of interleukin (IL)-8, IL-10, and tumor necrosis factor-alpha (TNF-α). Patients and Methods: The patients with cirrhosis underwent screening endoscopy and the ...
Shetty S S National institute of Immunohaematology (ICMR), KEM Hospital, Parel, Mumbai, 400 012, - - 2014
As compared to haemophilia, although the clinical features and the management strategies for rare coagulation factor deficiencies are discussed, little is known about them. This study was undertaken to assess the distribution, clinical presentation and treatment of patients with rare coagulation factor deficiency disorders in a cross-sectional population of India. ...
Sun Zhen Z Department of Cardiology, Shanghai Rui Jin - - 2014
Background: The present study investigated whether serum levels of soluble vascular endothelial growth factor receptor (sVEGFR)-1, -2 and -3 are related to poor coronary collateralization in patients with stable coronary artery disease (CAD). Methods and Results: Serum levels of sVEGFR-1, -2, -3, VEGF, and placental growth factor (PLGF) were determined in 403 ...
Kim Hyun-Ah HA Department of Neurology, Keimyung University School of Medicine, Daegu, Republic of Korea; Brain Research Institute, Keimyung University School of Medicine, Daegu, Republic of - - 2014
Vertebrobasilar ischemic stroke (VBIS) can cause acute hearing loss (AHL) because the vertebrobasilar system supplies most of the auditory system including the inner ear. The aim of this study was to assess the long-term prognosis of AHL associated with VBIS. Over 12.5years, 62 patients with AHL of a vascular cause ...
de Campos Guerra J C JC 1] Department of Pathology, University of São Paulo, São Paulo, Brazil [2] Department of Clinical Pathology, Hospital Israelita Albert Einstein, São Paulo, - - 2014
Study design:Although the knowledge described about risk factors and venous thromboembolism (VT) in the general population, the impact of these factors in the development of thromboembolic events in patients with spinal injury (SI) caused by spinal cord injury (SCI) is poorly understood.Objective:Evaluate the impact of risk factors in the development ...
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