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Juratli Tareq A TA University Hospital Dresden, Department of Neurosurgery, Fetscherstrasse 74, Dresden, Deutschland, Germany, 01307, 493514584909 ; - - 2014
The focus of this paper is to identify and quantify risk factors for early hemorrhagic progression of brain contusions (HPC) in patients with traumatic brain injuries (TBI) and to evaluate their impact on patients' outcome. Further, based on abnormal values in routine blood tests, the role of trauma induced coagulopathy ...
Sølvik Una Ø UO Department of Global Public Health and Primary Care, University of Bergen , - - 2014
Background. Biological variation is usually estimated in healthy individuals during steady-state conditions. The aim of this study was to estimate the in-treatment biological variation of the International normalised ratio (INR) and to investigate to what extent the different levels of coagulation factors could explain this variation. Methods. Blood samples were ...
Pasala Sanjiv S University of Arkansas for Medical Sciences College of Medicine, Arkansas Children's Hospital, Little Rock, Arkansas Department of Pediatrics, Divisions of Pediatric Critical Care*, Pediatric Hematology and Oncology†, Pediatric - - 2014
Acquired von Willebrand Factor (vWF) disease is associated with a decrease in the amount of circulating high molecular weight (HMW) vWF multimers. vWF has not been previously investigated in children on ECMO support.We hypothesized that HMW vWF multimers and vWF activity decrease over the course of ECMO support in these ...
Ohman M M Institution of Medicine and Public Health/Rheumatology, University of Umeå , - - 2014
Objectives: Patients with rheumatoid arthritis (RA) have increased mortality and morbidity due to cardiovascular disease (CVD). A high apolipoprotein (apo)B/apoA1 ratio is known to predict cardiovascular events (CVEs) in the population. apoA1 has, besides anti-atherogenic effects, anti-inflammatory properties. The importance of apolipoproteins in the development of CVEs, in the context ...
Talaat Roba M RM Molecular Biology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), Sadat City University, Sadat City, - - 2014
Hepatocellular carcinoma (HCC) is a hypervascular tumor characterized by neovascularization. The objective of the current study was to determine circulating proangiogenic [vascular endothelial growth factor (VEGF), platelet derived growth factor (PDGF), and tumor necrosis factor (TNF-α)] and antiangiogenic [IL-4, IL-12, interferon gamma-induced protein 10 (IP-10), and angiostatin] factors in Egyptian ...
Zotter Zsuzsanna - - 2014
Hereditary angioedema (HAE) resulting from C1-inhibitor deficiency is characterized by attacks of subcutaneous and submucosal edema. Many factors have been presumed to induce edema. Our study analyzed these factors in a fairly large patient population. In the first stage of our study, we analyzed the data recorded by 92 subjects ...
Arestedt Kristofer K 1Department of Medical and Health Sciences, Division of Nursing Science, Linköping University, Linköping, - - 2014
Background:The four-item Control Attitudes Scale (CAS) was developed to measure control perceived by patients with cardiac disease and their family members, but extensive psychometric evaluation has not been performed.Objective:The aim was to translate, culturally adapt and psychometrically evaluate the CAS in a Swedish sample of implantable cardioverter defibrillator (ICD) recipients, ...
Yu Hai H From the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, - - 2014
We investigated the predictors and outcomes of aneurysmal subarachnoid hemorrhage in patients with shunt-dependent hydrocephalus and make a preliminary inquiry into the relationship between the two. A consecutive cohort of 202 patients was evaluated, which included 40 shunt-dependent hydrocephalus patients. The basic characteristics on admission, complications of hemorrhage, management before ...
Bruins Slot Karsten M H KM Department of Internal Medicine, Oslo University Hospital, Oslo, - - 2014
Is treatment with factor Xa inhibitors associated with better efficacy and safety compared with the vitamin K antagonist warfarin for preventing strokes or other systemic embolic events in patients with atrial fibrillation? Compared with warfarin, factor Xa inhibitors are associated with a lower risk of stroke and other systemic embolic ...
Thorell S E SE School of Medicine, University of Manchester, Manchester, - - 2014
Coagulation screens are performed routinely in every hospital with the notion that an abnormal result will pick up low levels of coagulation factors and thus aid in determining patients' bleeding risk. We analysed all the clotting factor assays performed for abnormal clotting screen in a tertiary hospital over a 1-year ...
Qian Cheng C Department of Neurosurgery, Oulu University Hospital, Oulu, Finland. Electronic address: - - 2014
Seizures after primary intracerebral hemorrhage (PICH) are significant and treatable complications, but the factors predicting immediate, early and late seizures are poorly known. We investigated characteristics and outcome with special reference to occurrence and timing of a first seizure among consecutive subjects with PICH. A population-based study was conducted in ...
Kwaan Hau C HC Division of Hematology/Oncology, Olson Pavilion, Chicago, - - 2014
The hemostatic abnormalities seen in acute promyelocytic leukemia (APL) are unique and account for much of the morbidity and mortality of this disorder. Almost all patients present at diagnosis with laboratory findings of intravascular coagulation along with increased fibrinolysis. This unusual combination is correlated to the clinical manifestations with high ...
Abbas Zaigham Z Department of Medicine, Aga Khan University, Karachi, - - 2014
Background/Aim: We aimed to assess the influence of Helicobacter pylori and its virulent factors, cytotoxin associated gene (cag) A and E, on portal hypertensive gastropathy (PHG) and the levels of interleukin (IL)-8, IL-10, and tumor necrosis factor-alpha (TNF-α). Patients and Methods: The patients with cirrhosis underwent screening endoscopy and the ...
Shetty S S National institute of Immunohaematology (ICMR), KEM Hospital, Parel, Mumbai, 400 012, - - 2014
As compared to haemophilia, although the clinical features and the management strategies for rare coagulation factor deficiencies are discussed, little is known about them. This study was undertaken to assess the distribution, clinical presentation and treatment of patients with rare coagulation factor deficiency disorders in a cross-sectional population of India. ...
Sun Zhen Z Department of Cardiology, Shanghai Rui Jin - - 2014
Background: The present study investigated whether serum levels of soluble vascular endothelial growth factor receptor (sVEGFR)-1, -2 and -3 are related to poor coronary collateralization in patients with stable coronary artery disease (CAD). Methods and Results: Serum levels of sVEGFR-1, -2, -3, VEGF, and placental growth factor (PLGF) were determined in 403 ...
Kim Hyun-Ah HA Department of Neurology, Keimyung University School of Medicine, Daegu, Republic of Korea; Brain Research Institute, Keimyung University School of Medicine, Daegu, Republic of - - 2014
Vertebrobasilar ischemic stroke (VBIS) can cause acute hearing loss (AHL) because the vertebrobasilar system supplies most of the auditory system including the inner ear. The aim of this study was to assess the long-term prognosis of AHL associated with VBIS. Over 12.5years, 62 patients with AHL of a vascular cause ...
de Campos Guerra J C JC 1] Department of Pathology, University of São Paulo, São Paulo, Brazil [2] Department of Clinical Pathology, Hospital Israelita Albert Einstein, São Paulo, - - 2014
Study design:Although the knowledge described about risk factors and venous thromboembolism (VT) in the general population, the impact of these factors in the development of thromboembolic events in patients with spinal injury (SI) caused by spinal cord injury (SCI) is poorly understood.Objective:Evaluate the impact of risk factors in the development ...
Pourgheysari Batoul B aCellular and Molecular Research Center bPathology and Hematology Department cFaculty of Health, Shahrekord University of Medical Sciences, Shahrekord, - - 2014
Polymorphisms of coagulation factor XIII, an A2B2 tetramer, have been reported in correlation with venous and arterial thrombotic events. As there were limited data on these polymorphisms from Iranian population, we studied the correlation of factor XIIIA-Val34Leu and factor XIIIB-His95Arg with venous thromboembolism (VTE) in central Iran. Venous blood was ...
Lambrecht Stijn S Ghent University, Ghent, - - 2014
Transforming growth factor β superfamily members are involved in the pathogenesis of systemic sclerosis (SSc). Growth differentiation factor 15 (GDF-15) is a distant member of this family. We undertook this study to evaluate the role of GDF-15 in SSc pathogenesis. A longitudinal prospective cohort of SSc patients was screened for ...
Lee Jong Hwa JH Department of Physical Medicine and Rehabilitation and Regional Cardiocerebrovascular Center, Dong-A University Hospital, Busan, - - 2014
To demonstrate associating factors regarding nasogastric tube (NGT) removal in patients with dysphagia after stroke. This study is a retrospective medical chart review. Patients were divided into non-brain stem (NBS) and brain stem (BS) groups. A videofluoroscopic swallowing study was conducted until swallowing functions were recovered. Initial disease status was ...
Guddati Achuta K AK aDepartment of Internal Medicine, Massachusetts General Hospital, Harvard Medical School bDivision of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, - - 2014
Factor II inhibitors have been associated with an increased risk of bleeding. The management of patients with factor II inhibitors has not been adequately described. We describe a patient with an increased bleeding tendency due to factor II inhibitor who was unable to undergo surgery due to her bleeding tendency. ...
Zahedpanah Mahdi - - 2014
Introduction Hypercoagulable state is one of the common findings in beta-thalassemia intermedia (β-TI), particularly in splenectomized patients, with infrequent blood transfusion. Abnormality of the red blood cells (RBC) membrane due to oxidative damage is suggestive of possible etiologies. Membrane lipid peroxidation increases the exposure of phosphatidylserine (PS) that plays a ...
Zhang Xiaobin X Department of Psychiatry, Affiliated WuTaiShan Hospital of Medical College of Yangzhou University, Yangzhou, - - 2014
Some evidence suggests that neurotrophic growth factor systems might be involved in the etiology of major depressive disorder (MDD). Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor from the transforming growth factor-β family that plays a role in the development and function of the brain. This study aimed ...
Atsukawa Masanori M Division of Gastroenterology, Department of Internal Medicine, Nippon Medical School Chiba Hokusoh - - 2014
Much is unknown about the effect of 25-hydroxyvitamin D3 levels on the outcome of pegylated-interferon/ribavirin (peg-IFN/RBV) therapy for hepatitis C virus related cirrhosis. The purpose of the present study was to analyze and elucidate factors, including 25-hydroxyvitamin D3 , that contribute to a sustained virological response (SVR) in patients with ...
Bowry Ritvij R From the Department of Neurology, The University of Texas Medical School, Houston (R.B., S.F., J.M.A.-L., S.A.P., J.C.G.); and Center for Clinical and Translational Sciences, University of Texas at Houston (C.C., - - 2014
Factor Xa inhibitors are prescribed for stroke prevention in atrial fibrillation. Managing such patients is challenging especially if they are eligible for thrombolysis because there is no rapidly available test to detect the effect of such medications. Thrombelastography analyzes the dynamics of coagulation and can be rapidly performed. We sought ...
Pagoldh Maria M aDepartment of Internal Medicine and Geriatrics, Sahlgrenska University Hospital/Östra Hospital bInstitute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Göteborg cDepartment of Gastroenterology and Hepatology, Division of Gastroenterology, Karolinska Institute, Karolinska University Hospital dDepartment of Dental Medicine, Division of Periodontology, Karolinska Institute, Stockholm, - - 2014
Ulcerative colitis is a chronic inflammation limited to the large bowel. Early identification of reliable predictive markers addressing the risk of need for colectomy in a severe attack of ulcerative colitis is of crucial importance. To evaluate faecal characteristics and peripheral blood tests as predictive markers for subsequent risk of ...
Högler Wolfgang W Dept of Endocrinology and Diabetes, Birmingham Children's Hospital, - - 2014
Context: Acid labile subunit (ALS) deficiency, caused by IGFALS mutations, is a sub-type of primary IGF-I deficiency (PIGFD) and has been associated with insulin resistance (IR) and osteopenia. Whether patients respond to recombinant human IGF-I (rhIGF-I) is unknown. Objective and Design: This study determined the 14-hour pharmacokinetic (PK) response of ...
Renna Rosaria R Department of Neurology, Institute of Neurology, Catholic University, Rome, Italy. Electronic address: - - 2014
Approximately 10%-14% of ischemic strokes occur in young adults. To investigate risk factors and etiologies of strokes of young adults admitted to the "stroke unit" of Policlinico "Gemelli" of Rome from December 2005 to January 2013. In all, 150 consecutive patients younger than 50 years diagnosed with ischemic stroke were enrolled. Clinical ...
Ahluwalia Jasmina J Dept of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2014
Paroxysmal nocturnal hemoglobinuria(PNH) may present as cytopenia, hemolysis or thrombosis at unusual sites including splanchnic vessels. Thrombosis of the portal veins and hepatic veins are associated with thrombophilic risk factors -deficiencies of Protein C, S and antithrombin, positivity for antiphospholipid antibodies and Factor V Leiden mutation. There is limited information ...
Yu Tu-Nan TN Tu-Nan Yu, Bo Shen, Ning Meng, Hong Yu, Xiu-Jun Cai, The Second Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, - - 2014
To explore risk factors of lymphatic metastasis (LM) in gallbladder cancer, and their potential to complement unsatisfactory radiological detection. Radiological detection of LM by computed tomography (CT) was reported to fail in more than 60% of patients with pathological LM. In order to find risk factors highly suggestive of LM ...
Owczarek Danuta D Danuta Owczarek, Dorota Cibor, Mikołaj K Głowacki, Tomasz Mach, Department of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, 31-531 Kraków, - - 2014
Hypercoagulability observed in patients with inflammatory bowel diseases (IBD) may lead to thromboembolic events (TE), which affect the venous and arterial systems alike and are an important factor in patients' morbidity and mortality. The risk of TE in IBD patients has been demonstrated to be approximately three-fold higher as compared ...
Dunham C Michael CM Trauma/Critical Services, St, Elizabeth Health Center, 1044 Belmont Avenue, Youngstown, OH 44501, USA. - - 2014
Thromboelastography® (TEG) utilizes kaolin, an intrinsic pathway activator, to assess clotting function. Recent published studies suggest that TEG results are commonly normal in patients receiving warfarin, despite an increased International Normalized Ratio (INR). Because RapidTEG™ includes tissue factor, an extrinsic pathway activator, as well as kaolin, we hypothesized that RapidTEG ...
Ciriza-de-Los-Ríos C - - 2014
Background: High-resolution manometry (HRM) is a breakthrough in the morphological study of the gastroesophageal junction (GEJ) and its degrees of disruption.Objectives: a) Assessment of risk factors involved in the disruption of the GEJ in patients with gastroesophageal reflux (GER) symptoms; b) the relationship between the type of GEJ and GER ...
Sola-Vera J - - 2014
Background: Various studies and two meta-analysis have shown that a variable stiffness colonoscope improves cecal intubation rate. However, there are few studies on how this colonoscope should be used.Objective: The aim of this study was to identify factors related to the advancement of the colonoscope when the variable stiffness function ...
Van Dreden Patrick P Diagnostica Stago, 125 Avenue Louis Roche, 92635 Gennevilliers Cedex, - - 2014
Brain contains large amounts of tissue factor, the major initiator of the coagulation cascade. Neuronal apoptosis after intracerebral haemorrhage (ICH) leads to the shedding of procoagulant phospholipids (PPLs). The aim of this study was to investigate the generation of PPL, tissue factor activity (TFa), and D-Dimer (D-Di) in the cerebrospinal ...
Paladino Nunzia Cinzia - - 2013
The aim of this retrospective study was to evaluate the impact of some risk factors on mortality in patients with Acute mesenteric ischemia (AMI). From September 2003 to August 2011, 200 patients were operated on for bowel infarction at our unit: 149 were included in the study. For each patient, ...
Vellimana Ananth K AK 1Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri, USA 2Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA 3Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, - - 2013
Carotid endarterectomy (CEA) for symptomatic carotid artery stenosis and intravenous tPA (IV-tPA) for acute ischemic stroke are proven therapies; however, the safety of CEA in stroke patients who recently received IV-tPA has not been established. To evaluate the safety of CEA in stroke patients who recently received IV-tPA. A retrospective ...
Gondo Tatsuo - - 2013
The risk factors of incisional surgical site infection (iSSI) after open radical cystectomy (ORC) have not been fully investigated. The aim of the present study is to examine factors correlated with iSSI development after ORC with intestinal urinary diversion. A total of 178 patients who had undergone ORC with intestinal ...
Noma Hidetaka - - 2013
The association of inflammatory factors and the aqueous flare value with macular edema in central retinal vein occlusion (CRVO) patients remains unclear. We investigated the relations between the aqueous flare value and vitreous levels of vascular endothelial growth factor (VEGF), soluble intercellular adhesion molecule-1 (sICAM-1), and interleukin-6 (IL-6) in patients ...
Oi Hidekazu - - 2013
The purpose of this study was to evaluate the possibility of establishing predictors of mortality in women with amniotic fluid embolism. Our previous report identified eight factors associated with amniotic fluid embolism (AFE) fatality: dyspnea, cardiac arrest, loss of consciousness, serum sialyl Tn greater than 47 U/mL, serum interleukin-8 greater than ...
Bilgir Oktay - - 2013
In a majority of patients with nonalcoholic fatty liver disease (NAFLD), cardiovascular risk factors including diabetes mellitus type 2, abdominal obesity, and metabolic syndrome are present. The purpose of this study is to investigate the presence of endothelial injury and the changes in coagulation parameters in NAFLD patients. For this ...
Araujo Antonio Santos de AS Junior Hospital Sírio-Libanês, Brazil, Sao - - 2013
Decompressive craniectomy (DC) is gaining an increasing role in the neurosurgical treatment of intractable intracranial hypertension, but not without complications. A rare complication is the "syndrome of the trephined" (ST). It occurs when the forces of gravity overwhelm intracranial pressures, leading the brain to become sunken. Objective To determine the ...
Girolami A A Department of Medicine, University of Padua Medical School, Padua, - - 2013
Congenital Factor VII (FVII) deficiency can be divided into two groups: cases of "true" deficiency, or cross-reactive material (CRM) negative and variants that are cross-reactive material positive.The first form is commonly recognized as Type I condition whereas the second one is known as Type II. FVII deficiency has been occasionally ...
Dutta Mainak M RMO-cum-Clinical Tutor, Department of Otorhinolaryngology and Head-Neck Surgery, Medical College and Hospital , Kolkata, India - - 2013
Recurrent Acute Exacerbations of Chronic Rhinosinusitis (AECRS) in a setting of atrophic rhinitis are perplexing clinical situations. While either may act as the primary factor, repeated inflammation in a vessel-poor atrophied tissue is unusual. Progressive mucosal degeneration, vascularity and the effect of bacterial colonization are the factors suggested to play ...
Kim Young-Soo YS Department of Neurology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South - - 2013
Hyponatremia is one of the most common adverse effects in patients treated with oxcarbazepine (OXC). Most patients with OXC-induced hyponatremia are asymptomatic, so the presence of severe or symptomatic hyponatremia, which requires electrolyte correction or discontinuation of OXC therapy, has more important clinically implications. However, data for OXC-induced severe and ...
Castejon Raquel - - 2013
Objective. Endothelial progenitor cells (EPCs) play an important role in vascular damage repair and it has been suggested that a decreased number of these cells is associated with increased subclinical atherosclerosis. Our study aim was to evaluate whether the number of circulating EPCs in patients with SLE is associated with ...
Sarkar Esha - - 2013
Complement dysregulation from an uncontrolled activation of the alternate pathway can be mediated by C3 Nephritic Factor and results in C3 glomerulopathy. Identification of C3 degradation products C3c and C3d in patient serum provides evidence of uncontrolled complement activation. It is possible to detect C3c and C3d in patient serum ...
Avila-Díaz Marcela - - 2013
Cardiac valve calcification (VC) is a frequent complication in chronic renal disease and is considered a risk factor for all-cause and cardiovascular mortality. However, little is known about the pathophysiology mechanisms that originate it and the factors associated with its development. We undertook this study to analyze the frequency and ...
Azuma Naoto - - 2013
Objective. To assess changes in salivary epidermal growth factor (EGF) levels and the correlation between these levels and the severity of intraoral manifestations in Sjögren's syndrome (SS). Methods. Forty SS patients and 23 controls were enrolled. Salivary EGF concentration was measured using an enzyme-linked immunosorbent assay, and intraoral manifestations were ...
Janning M - - 2013
Background: Acquired factor XIII (FXIII) deficiency is associated with reduced clot firmness and increased bleeding in patients undergoing major surgery. In contrast, only limited information is available on the haemostatic relevance of acquired FXIII deficiency in non-surgical patients. Case report: An 81-year-old patient, who had experienced acute type-A dissection of ...
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