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Oeda Tomoko - - 2013
Abnormal posture (AP) is often seen in Parkinson's disease (PD), and marked forms known as dropped head syndrome and camptocormia encumber daily living activities. Unlike other motor disabilities such as bradykinesia or muscular rigidity, AP is not always improved but rather deteriorated by PD medication. To clarify factors associated with ...
Corey Kathleen E KE Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of - - 2013
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide and its progressive form, steatohepatitis, will be the leading indication for liver transplant by 2020. While risk factors for steatohepatitis have been identified, little work has been performed to identify factors protective against NAFLD development. This ...
Manafi Rasi Alireza A Department of Orthopedic and Trauma Surgery, Shahid Beheshti University of Medical Sciences, Imam Hossein Hospital, Tehran, IR - - 2013
There is controversy regarding routine prophylaxis for deep vein thrombosis (DVT) in patients treated via a short leg cast or splint following lower extremity trauma. The main aim of this study is to evaluate the incidence of DVT and need for chemoprophylaxis in these patients. Patients with ankle sprains or ...
Madziarska Katarzyna K Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, - - 2013
Introduction: The aim was to identify factors carrying an ominous prognosis in a cohort of diabetic patients (pts) on a hemodialysis (HD) and peritoneal dialysis (PD) program. Materials and methods: We analyzed survival rates of 61 diabetic dialysis pts (35 HD/26 PD). The participants were matched in baseline characteristics, standard ...
Naderi M M Genetic Researcher Center in Non-Communicable Disease, Zahedan University of Medical - - 2013
Factor XIII or "fibrin-stabilizing factor," is a transglutaminase circulates in the blood circulation as a hetero tetramer with two catalytic A subunits and two carrier B subunits. This important coagulation factor has a crucial role in clotting cascade and produces strong covalent bonds between soluble formed fibrin monomers during coagulation. ...
Lasek-Bal Anetta A Stroke Unit, Department of Neurology, Clinical Hospital No 7, Medical University of Silesia, Professor Leszek Giec Upper Silesian Medical Centre, Katowice, - - 2013
Patent foramen ovale and atrial septal aneurysm are considered to be factors conducive to the occurrence of stroke and transient ischaemic attacks. However, there is no clear answer to the question whether patent foramen ovale is an independent risk factor for stroke and what the mechanism of potential cerebral ischaemia ...
Giacchino Maria M Gastroenterology Unit, Departments of "Internal Medicine, University of Genoa (Maria Giacchino, Vincenzo Savarino), Genoa, - - 2013
Non-erosive reflux disease (NERD) and functional heartburn (FH) are two different clinical entities and the clear distinction between the two forms is actually possible thanks to the use of impedance-pH monitoring. NERD is the more common manifestation of gastro-esophageal reflux disease (GERD), one of the most widespread chronic gastrointestinal disorders ...
Chitalia Vipul C - - 2013
Stent thrombosis (ST), a postinterventional complication with a mortality rate of 50%, has an incidence that rises precipitously in patients at risk. Chronic renal failure and end-stage renal disease have emerged as particularly strong ST risk factors, yet the mechanism remains elusive. Tissue factor (TF) is a crucial mediator of ...
Bota Simona - - 2012
Our study tried to identify the factors associated with discordance between liver stiffness values assessed by acoustic radiation force impulse (ARFI) elastography and histologic fibrosis in 106 chronic hepatitis C patients. Liver biopsy (LB) and ARFI measurements were performed in the same session. A discordance of at least two stages ...
Lee Han Sook - - 2012
Ergonovine have been used for the prevention and treatment of postpartum or postabortion hemorrhage. Although this modality has been considered relatively safe in the obstetric patients, there were a few cardiac events associated with this drug in the post-delivery or post-abortion patients, especially in patients with cardiovascular risk factors. We ...
Lee Ban Seok - - 2012
BACKGROUND: Bacteremic cholangitis carries a high mortality rate of up to 10 % in relation to organ failure (OF), including septic shock. AIM: The purpose of this study was to elucidate predictive factors for OF in bacteremic cholangitis. METHODS: A retrospective review of all patients diagnosed with acute cholangitis and proven ...
Antunes-Lopes Tiago - - 2012
PURPOSE: We investigated urinary levels of nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor in healthy individuals and patients with overactive bladder. MATERIALS AND METHODS: Urine from 40 healthy volunteers, half of them male and half female, was collected in the morning, afternoon and evening on ...
Rodríguez-González Raquel - - 2012
OBJECTIVE: Platelet derived growth factor-CC (PDGF-CC) isoform is activated by tissue plasminogen activator (tPA) regulating blood brain barrier permeability after ischemia. We aimed to study the association of PDGF isoforms serum levels with hemorrhagic transformation (HT) and edema after thrombolytic treatment in ischemic stroke. METHODS: We studied 129 patients with ...
Chen Hui - - 2012
INTRODUCTION: The relationship between the imbalance in pro- and anti-coagulant factors and portal vein thrombosis (PVT) in individuals with cirrhosis is unclear. The aim of this study was to determine whether the imbalance in pro- and anti-coagulant factors contributes to the development of PVT in cirrhotic patients. MATERIALS AND METHODS: ...
Nordenstedt Helena H Houston VA HSR&D Center of Excellence, Houston, TX, - - 2013
Recent studies using histology alone in select patients have suggested that Helicobacter pylori-negative gastritis may be common. The objective of this study was to investigate the prevalence of H. pylori among individuals with histologic gastritis. Subjects between 40 and 80 years underwent elective esophagogastroduodenoscopy at a VA Medical Center. Gastric ...
Hirano Kenji - - 2012
OBJECTIVES: This study aimed to investigate risk factors for pancreatic stones and atrophy in autoimmune pancreatitis (AIP). METHODS: Seventy-one patients with AIP observed for more than 1 year were enrolled. The frequency of pancreatic stone development and atrophy on computed tomography as well as their risk factors were examined. RESULTS: ...
Genét Gustav Folmer - - 2012
It remains debated whether traumatic brain injury (TBI) induces a different coagulopathy compared to non-TBI. This study investigated traditional coagulation tests, biomarkers of coagulopathy and endothelial damage in trauma patients with and without TBI. Blood from 80 adult trauma patients were sampled (median of 68 min (IQR 48-88) post-injury) upon ...
Kaur Sharandeep - - 2012
Acute liver failure (ALF) is a life threatening condition characterized by jaundice, encephalopathy and coagulopathy leading to multiorgan failure in a patient with no prior history of liver disease. Forty three consecutive patients of ALF admitted in Pediatric ICU were studied for etiology and prognostic factors. Etiology was established in ...
Sarlati Fatemeh - - 2012
OSTEOCLASTOGENESIS IS COORDINATED BY THE INTERACTION OF THREE MEMBERS OF THE TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY: Osteoprotegerin (OPG)/receptor activator of nuclear factor kappa B ligand (RANKL)/receptor activator of nuclear factor kappa B (RANK). The aim of this study was to investigate RANKL and OPG levels, and their relative ratio in ...
Ghamar-Chehreh Mohammad Ebrahim - - 2012
There are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (NAFLD) in different populations. However, the existing literature lacks powerful studies addressing the factors which may predict the severity of NAFLD. In the current study, we aimed to evaluate factors independently associated with liver ...
Kanat Ayhan - - 2012
To characterize the importance of the vertical angle of the sacral curvature (VASC) in lumbar disc herniations. Morphological data derived from lumbar sagittal MRI imaging. The statistical significance of the findings are discussed. The angles of 60 female patients with lumbar disc herniations (LDH) were compared with the 34 female ...
Silver Richard M - - 2012
Racial disparities appear to exist in the susceptibility and severity of systemic sclerosis (SSc, scleroderma) and are responsible for a greater health burden in blacks as compared with whites. Disparities in socioeconomic status and access to healthcare do not sufficiently explain the observed differences in prevalence and mortality. It is ...
Junttila Eija - - 2012
BACKGROUND:Electrocardiographic (ECG) abnormalities are frequent in patients with intracranial insult. In this study, we evaluated the factors predisposing to the repolarization abnormalities, i.e., prolonged corrected QT (QTc) interval, ischemic-like ECG changes and morphologic end-repolarization abnormalities, and examined the prognostic value of these abnormalities in patients with subarachnoid and intracerebral hemorrhages ...
Bittar Luis Fernando - - 2012
Increased levels of factor VIII (FVIII) are a prevalent and independent risk factor for deep venous thrombosis (DVT). After a median of 10 years of the first DVT, we evaluated FVIII coagulation levels in 55 patients with DVT of the lower limbs and previous high levels of FVIII and in ...
Matsuoka Masatake - - 2012
Factor XIII (FXIII) is the final enzyme in the coagulation cascade. Acquired FXIII deficiency is caused by inhibitors of FXIII or decreased synthesis and/or increased consumption of FXIII, which leads to severe bleeding. Recently, we experienced a case of hemorrhagic-acquired factor XIII deficiency that occurred during treatment with the IL-6 ...
Lee Ji-Seon - - 2012
OBJECTIVE: In ankylosing spondylitis (AS), the cervical spine, like other sections of the spine and sacroiliac joints, is vulnerable during the disease process. Atlantoaxial subluxation (AAS) has been studied in connection with AS, but its risk factors and progression have not been clarified. Therefore, this study assessed the prevalence and ...
Martinelli Ida - - 2012
Cerebral sinus-venous thrombosis (CSVT) is a rare life-threatening disease with an estimated annual incidence of 3-4 cases per million in adults and 7 cases per million in neonates. Brain tumors, cerebral infections and traumas are local risk factors for CSVT, but the commonest encountered risk factors are oral contraceptive use, ...
Hall D P DP Department of Critical Care, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, - - 2012
Fresh-frozen plasma (FFP) is widely used in critically ill patients, despite a weak evidence base. Factors that influence the decision to transfuse FFP before intravascular catheter insertion are poorly described. We undertook a case-controlled study based on a prospective cohort study of 1923 admissions to 29 intensive care units in ...
Huang Yu-Hua - - 2012
Epidural hemorrhage (EDH) that develops remote to the decompressed hemisphere is a devastating morbidity after hemicraniectomy for traumatic brain injury (TBI). In this study, we aimed to investigate the incidence, risk factors, and outcome influence of postcraniectomy remote EDH. For this retrospective study, we enrolled 139 patients undergoing unilateral hemicraniectomy ...
Yugué Itaru - - 2012
STRUCTURED ABSTRACT: Study Design. A retrospective, consecutive case series.Objective. To determine the risk factors that have a statistically significant association with the need of tracheostomy in the patients with cervical spinal cord injury (CSCI) at the acute stage.Summary of Background Data. Respiratory complications remain major cause of further morbidity and ...
Bai Jie - - 2012
We investigated the correlation between body weight index (BWI) and the effective power of erythrocytapheresis in patients with polycythemia vera (PV) who received therapeutic erythrocytapheresis (TEA). Furthermore, the risk factors of the adverse events related to erythroapheresis therapy were analyzed. Two hundred and seventeen cycles of therapeutic erythrocytapheresis were carried ...
González-López Julio J - - 2012
Purpose:  To evaluate the positivity rate of temporal artery biopsies (TAB) performed in suspects of giant cell arteritis (GCA) and to study the epidemiological and clinical factors associated to the biopsy result. Methods:  A retrospective, multicenter, case-control study was performed, including three hundred and thirty-five patients who underwent TAB for ...
Hua Feng - - 2012
BACKGROUND: Recent clinical data suggest that treatment with terlipressin (TP) may be more advantageous for septic shock than catecholamines. However, it is unknown whether TP would be effective for acute respiratory distress syndrome (ARDS) patients with shock. OBJECTIVES: The aim of this study was to compare the impact of TP ...
Sedney Cara L - - 2012
Listeria monocytogenes is a known cause of meningitis, but cerebral abscess formation is exceedingly rare. We describe a patient who presented with an unsteady gait and a small ring-enhancing lesion in the right parietal lobe. Pathologic evaluation demonstrated an abscess with associated microglial nodules, and culture revealed Listeria. In spite ...
Ddine Lissa Chamse - - 2012
BACKGROUND - Chronic gastritis is an inflammation of the stomach mucosa, which is considered its main etiological factor the Helicobacter pylori. AIM - To observe the differences in patients with chronic gastritis as well as the presence and absence of H. pylori, to obtain a better understanding of the etiological ...
Shi Yi Nan - - 2012
  We aimed to determine the prevalence of eosinophilic esophagitis (EoE) and define its clinical and endoscopic characteristics in Chinese patients.   Esophageal specimens obtained from January 2006 to December 2010 in the First Affiliated Hospital of Sun Yat-sen University were reviewed, and the data on clinical characteristics and endoscopic ...
Joo Moon Kyung - - 2012
  This study was aimed to evaluate the prevalence of eosinophilic esophagitis (EoE) among patients with esophageal or upper gastrointestinal (UGI) symptoms.   Patients with esophageal or UGI symptoms including dysphagia food impaction, acid regurgitation, heartburn, chest pain, epigastric pain, nausea and/or vomiting were prospectively collected. The enrolled patients responded ...
Suh Yoon Jung - - 2012
Vascular rings refer to anomalies of the great arteries that cause respiratory or feeding problems. The purpose of this study was to analyze a series of patients with vascular rings and evaluate associated risk factors for mortality. A retrospective review of all patients identified with vascular rings between 1997 and ...
Roubík Karel - - 2012
Introduction: The use of helium-oxygen mixture (heliox) for ventilation has an advantage in patients with obstruction of the airways. The physical properties of helium enable an easier gas flow through the airways; this enables easier breathing for the patient when compared to standard ventilation of air. A high cost of ...
Satar Bulent - - 2012
The objective of this study was to present clinical, audiological, and radiologic findings of a rare case of the temporomandibular joint herniation associated with lymphangioma of the parotid region. A 21-year-old man with the complaints of a mass on the right side of the face, otalgia, and hearing loss in ...
Vergnat Mathieu - - 2012
Reports indicate that repair procedures for ischaemic mitral regurgitation (IMR) are less durable than previously thought. Repair failure has been shown to be stress related. Leaflet curvature is the major determinant of valve stress. Theoretical and animal experiments have shown that saddle-shaped annuloplasty optimizes leaflet curvature when compared with standard ...
Kir Mustafa - - 2012
This study aimed to evaluate the presenting symptoms, the effectiveness of imaging methods, and the surgical treatment of vascular rings. Data for 44 patients (32 enrolled prospectively, 12 reviewed retrospectively) over a 10-year period in a tertiary referral center were analyzed. These patients comprised 25 patients with a left aortic ...
Turkmen K - - 2012
Background:  Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Aim:  The aim of this study was to investigate coronary flow velocity reserve (CFVR) as a marker of endothelial dysfunction, carotid intima media thickness (CIMT) as a marker of subclinical ...
Hassan Rosline - - 2012
Menorrhagia is one of the gynecological complaints, seen in women of reproductive age. In majority of cases no organic pathology is found. To date there is no consensus on application of von Willebrand disease (vWD) testing as part of the routine investigations in menorrhagia. Diagnosis of vWD is challenging. It ...
Ferrara Joseph M - - 2012
BACKGROUND: We report four patients who developed periodic eyelid opening following hypoxic ischemic injury. This manuscript reviews the clinical course of our patients as well as previously published cases and discusses the neuroanatomical basis of eyelid opening. METHODS: Data were collected from the patients' electronic medical record and digital electroencephalography ...
Rodríguez-Blanco M - - 2012
We describe a 42 year-old patient who developed acute myopia and closed-angle glaucoma one week after beginning treatment with topiramate. Ultrasound biomicroscopy revealed a bilateral angle closure and choroidal effusion. The clinical findings resolved with withdrawal of the topiramate. Topiramate may cause acute myopia and closure angle glaucoma in some ...
Röösli Christof - - 2012
OBJECTIVE: This study aimed to determine how tympanic membrane (TM) perforations and their closure, using a paper-patch technique, affect middle-ear mechanics and, thus, conductive hearing for different sizes of the TM perforation. STUDY DESIGN: Temporal bone (TB) study and prospective clinical trial. SETTING: Tertiary referral center. PATIENTS: Nine patients with ...
Samková Aneta - - 2012
The incidence of venous thromboembolism (VTE) during childhood is low with two peaks - neonatal and adolescent age. This retrospective study is focused on clinical characteristics ofVTE during adolescence. The main goals are to assess the most frequent inherited and acquired risk factors and to evaluate the benefit of D-dimers ...
Mannucci Pier Mannuccio - - 2012
Multiple and complex abnormalities of hemostasis are revealed by laboratory tests in such common diseases as cirrhosis and end-stage renal insufficiency. Because these abnormalities are associated with a bleeding tendency, a causal relationship is plausible. Accordingly, an array of transfusional and nontransfusional medications that improve or correct these abnormalities is ...
Robson Anthony G - - 2012
To assess the significance and evolution of parafoveal rings of high-density fundus autofluorescence (AF) in 12 patients with retinitis pigmentosa (RP). Twelve patients with autosomal recessive RP or Usher syndrome type 2 were ascertained who had a parafoveal ring of high-density AF and a visual acuity of 20/30 or better ...
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