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Di Fabio R - - 2014
To date, there exist no data reporting the level of suitability of requests for electromyography examinations (EMGs) in Rome. The records of 1,220 consecutive patients (age: 57.6±15.0 years; 400 M, 820 F) in two neurophysiology laboratories were collected and analyzed. In total, 1,317 EMGs were requested, mainly by general practitioners ...
Thonnard M - - 2014
Zolpidem has been reported as an "awakening drug" in some patients with disorders of consciousness (DOC). We here present the results of a prospective openlabel study in chronic DOC patients. Sixty patients (35±15 years; 18 females; mean time since insult ± SD: 4±5.5 years; 31 with traumatic etiology) with a ...
Dell׳Osso Bernardo B Dipartimento di Fisiopatologia medico-chirurgica e dei trapianti, Università degli Studi di Milano, Dipartimento di Salute Mentale, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy. Electronic address: - - 2014
The brain derived neurotrophic factor (BDNF) gene and its epigenetic regulation have been repeatedly implicated in the pathophysiology of mood disorders. Following previous investigation in the field, we further investigated differences in BDNF promoter gene methylation in patients with mood disorders, comparing unipolar and bipolar subjects, on the basis of ...
Bennett Noel M NM From the *Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, MN; †University at Buffalo, Buffalo, NY; and ‡Cedars-Sinai Heart Institute, Los Angeles, - - 2014
Patients with refractory angina (RA) have limited therapeutic options and significant limitations in their quality of life. Ranolazine is approved for patients with chronic stable angina but has not been studied in patients with RA. The Ranolazine Refractory Angina Registry was designed to evaluate the safety, tolerability, and effectiveness in ...
Argenziano Giuseppe G aSkin Cancer Unit bDermatology and Skin Cancer Unit, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia cDepartment of Dermato-Oncology, San Gallicano Dermatological Institute, IFO of Rome, Rome, Italy dSkin Spectrum Medical Services, Como, Western Australia, Australia eDepartment of Dermatology, Medical University of Graz, Graz fDepartment of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria gState Clinic of Dermatology, Hospital of Skin and Venereal Diseases, Thessaloniki, Greece hPublic, Private and Teaching Practice of Dermatology, Konstanz, Germany iClinic of Dermatovenereology Medical University of Nis, Nis, - - 2014
Patients with a high total nevus count (TNC) merit a total-body examination, but a simple strategy to identify these high-risk individuals is essentially missing. The aim of this study was to investigate the correlation between the number of melanocytic nevi on both arms and the TNC, and to evaluate patient ...
Heard Bryan J BJ McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta, Canada Department of Surgery, University of Calgary, Calgary, Alberta, - - 2014
The objective of this study was to develop a method for categorizing normal individuals (normal, n = 100) as well as patients with osteoarthritis (OA, n = 100), and rheumatoid arthritis (RA, n = 100) based on a panel of inflammatory cytokines expressed in serum samples. Two panels of inflammatory ...
Mohamad Yadzir Zailatul Hani ZH Allergy and Immunology Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia. - - 2014
Component-resolved diagnosis (CRD) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. The aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (SPT).45 patients with allergic rhinitis were studied (16 children and ...
Shinto Ajit S AS From the *Nuclear Medicine Department and Psychiatry Department, †KMCH, Coimbatore, Tamil Nadu, India; ‡Vazhikatti Mental Health Centre and Research Institute, Coimbatore, TN, India; and §PSG Institute of Medical Sciences and Research, Coimbatore, TN, - - 2014
Decreased frontal activity has been reported widely in unmedicated schizophrenic patients with predominantly negative symptoms. Not many studies have assessed the frontal lobe status in unmedicated patients with positive symptoms. Fifty-one patients with schizophrenia (all unmedicated, 38 never medicated) and 12 healthy age-matched controls were evaluated with FDG PET CT. ...
San Juan-Acosta Mileidis M Virgen Macarena Hospital, Sevilla, - - 2014
Colon capsule endoscopy (CCE) is a new endoscopic technique that is minimally invasive and allows evaluation of the colon mucosa without pain, sedation, and gas insufflation. To date, few studies have investigated the use of CCE in patients with ulcerative colitis (UC). This study compares the ability of CCE and ...
Chen Wei-Ji WJ 1From the Chest Division, Department of Internal Medicine, Mackay Memorial Hospital , Taipei , - - 2014
ABSTRACT Background: To evaluate the incidence of pulmonary embolism (PE) in patients with chronic obstructive pulmonary disease (COPD) in Taiwan. Methods: This was a retrospective population-based cohort study using data retrieved from Taiwan's National Health Insurance Research Database (2000 to 2008), which contains 99% of Taiwanese healthcare data. The evaluations ...
Iori M M Unit of Cardiac Surgery Department of Cardiology Thoracic and Vascular Surgery and Critical Care Medicine, Azienda Ospedaliera ASMN Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy - - - 2014
Clinical experience shows that about 2 out of 3 patients with indication to resynchronization therapy (CRT) may have improvements in NYHA class, echocardiographic parameters and survival. However, specific clinical or technical parameters that identify responder patients have not yet been found. Aim of the present study was to assess the ...
Keskin D - - 2014
Angiogenesis plays an important role in the pathogenesis of inflammatory diseases, but the possible role of angiogenesis in Behçet's disease (BD) has not yet been studied. The aim of this study was to determine angiostatin levels in patients with BD and the role of angiogenesis in the pathogenesis of the ...
Weinberg Olga K OK From the Boston Children's Hospital, Boston, MA; - - 2014
Acute myeloid leukemia (AML) with monosomal karyotype (MK) recently has been reported to be associated with worse outcome than the traditional complex karyotype. In this retrospective study of 111 patients with AML, we identified 14 patients with MK (13% of all patients with AML) using the definition proposed by Breems ...
Teishima Jun J Department of Urology, Institute of Biomedical and Health Sciences, Integrated Health Sciences, Hiroshima University, Hiroshima 734-8551, - - 2014
The present study aimed to investigate the impact of pre-treatment C-reactive protein (CRP) levels on the prediction of prognosis in patients with metastatic renal cell carcinoma (mRCC), who were classified as intermediate-risk patients using the Memorial Sloan Kettering Cancer Center (MSKCC) risk classification and who received molecular targeted therapy. The ...
Guo Wenjian W Department of Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 0577, P.R. - - 2014
The antitumor effect of natural killer T cells has been reported in several studies analyzing the expression of CD1d on antigen-presenting cells (APCs). Therefore, the present study questioned whether APCs may be abnormal in the peripheral blood (PB) of acute leukemia (AL) patients, particularly the levels of CD1d. To improve ...
Andereggen Lukas - - 2014
Male patients with prolactinoma commonly present with macroadenoma and a history of long-standing hypogonadism. Data regarding the effect of hypogonadism on bone health in these patients are scarce. The present study compared the long-term results of male patients with prolactinomas treated primarily either surgically or medically. This retrospective study evaluated ...
Park Hee Jin HJ 1 Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, - - 2014
OBJECTIVE. The purpose of this study was to determine whether each grade in a new system suggested by Park et al. (Park system) to assess cervical neural foraminal stenosis validly correlates with the associated clinical findings and to evaluate the interobserver agreement in grading between two MRI readers. MATERIALS AND ...
Van Gent Jan-Michael JM From the Trauma Service, Scripps Mercy Hospital, San Diego, - - 2014
Traumatic brain injury (TBI) is considered an independent risk factor of venous thromboembolism (VTE). However, the role of TBI severity in VTE risk has not been determined. We hypothesized that increased severity of brain injury in patients with isolated TBI (iTBI) is associated with an increased incidence of VTE. The ...
Colling Kristin P KP From the Department of Surgery (K.P.C., G.J.B.), University of Minnesota Medical Center, Minneapolis; and North Memorial Medical Center (E.D.I., M.C.B., P.R., W.A.D., K.R., J.G., G.J.B.), Robbinsdale, - - 2014
Computed tomography (CT) with intravenous (IV) contrast is an important step in the evaluation of the blunt trauma patient; however, the risk for contrast-induced nephropathy (CIN) in these patients still remains unclear. The goal of this study was to describe the rate of CIN in blunt trauma patients at a ...
Danforth Teresa L TL Department of Urology, SUNY Buffalo School of Medicine and Biomedical Sciences, Buffalo General Hospital, 100 High Street, Suite B280, Buffalo, NY 14203, USA. Electronic address: - - 2014
Neurogenic lower urinary tract dysfunction (NLUTD) affects many patients and requires close monitoring. Initial studies establishing patients at risk for upper tract disease revealed that high detrusor leak point pressures were predictive of upper tract disease. Urodynamics in patients with NLUTD have specific challenges. Initial studies in patients after an ...
Dillon Benjamin E BE Department of Urology, Kelsey-Seybold Clinic, 2727 West Holcomb, Houston, TX 77005, - - 2014
Multiple sclerosis (MS) is an autoimmune inflammatory disease that results in damage to the myelin sheaths of the nerves in the central nervous system. Urinary urgency, frequency, and urgency incontinence are the most common symptoms, occurring in 37% to 99% of patients. Voiding symptoms (hesitancy, feeling of incomplete bladder emptying, ...
DeLong Michael R MR Durham, N.C. From the Division of Plastic and Reconstructive Surgery, Department of Surgery, and the Departments of Biostatistics and Bioinformatics and Radiology, Duke University Medical - - 2014
The profunda artery perforator flap is a new option for breast reconstruction in appropriate patients. While the basic anatomy is known, detailed profunda perforator anatomy has never fully been described and we present new data that will aid dissection. Fifty consecutive lower extremity computed tomography angiogram scans (100 legs) were ...
Pranteda G G Unit of Dermatology, NESMOS Department, Faculty of Medicine and Psychology, "Sapienza" Ospedale Sant'Andrea, Rome, Italy - - - 2014
Basal cell carcinoma (BCC) is the most common skin malignant neoplasm in humans. Its localization and its clinical-pathological aspects are fundamental for the treatment and the outcome of these tumors. We wanted to verify if different clinical-pathological subtypes of BCC may be present with different frequencies on single skin areas. ...
Conte Carmela C Rehabilitation Centre, Movement Analysis LAB, Policlinico Italia, Rome, - - 2014
Although abnormal oscillations of the trunk are a common clinical feature in patients with cerebellar ataxia, the kinematic behaviour of the upper body in ataxic patients has yet to be investigated in quantitative studies. In this study, an optoelectronic motion analysis system was used to measure the ranges of motion ...
Kim Sei Won SW Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Catholic University of Korea, Seoul, South - - 2014
Pulmonary infections are a major cause of morbidity and mortality in patients with hematologic malignancy. Bronchoscopy is at present still the traditional first investigation in immunosuppressed patients that have developed pulmonary infiltrates. There is limited data available on the validity of fiberoptic bronchoscopy (FOB) with bronchoalveolar lavage (BAL) to determine ...
Sorkhabi Rana R Tabriz University of Medical Sciences, Tabriz, Iran, - - 2014
To determine the concentration of inflammatory mediators in the tear film of patients with keratoconus. Basal tears from patients with keratoconus and from normal controls were collected using a capillary tube. Patients with keratoconus were examined in a routine fashion, and keratometric readings were also taken from corneal topographic maps ...
Namm Jukes P JP Department of Surgery, University of Chicago, Chicago, IL, - - 2014
When microinvasion cannot be ruled out on core needle biopsy (CNB) in the setting of ductal carcinoma in situ (DCIS), the surgeon must decide whether to perform a sentinel lymph node biopsy (SLNB) at the time of surgery. Up to 10 % of patients with T1mi have nodal disease, but the ...
Almalki Mussa H MH Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh, Saudi Arabia, - - 2014
The management of giant prolactinomas remains a major challenge, despite dopamine agonists being the first line of treatment, owing to its efficacy to normalize prolactin levels and reduce tumor volume. The aim of this study is to characterize the therapeutic aspects, manifestations and outcomes of 16 cases of giant prolactinomas ...
Li Da-Wei DW Department of Neurology, Neurobiology and Geriatrics, National GCP Clinical Trial Center on Neurodegenerative Disease, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, #45 Changchun Street, Beijing, 100053, - - 2014
Non-motor symptoms (NMS) are common among patients with Parkinson's disease (PD). However, reports on NMS in Chinese PD population are scarce. Little is known about NMS in patients with Asian specific leucine-rich repeat kinase 2 (LRRK2) variants in G2385R and R1628P. This study aimed to elucidate the clinical characteristics of ...
Chellamuthu Santhi S Santhi Chellamuthu, Steven M Thomas, Catherine Hill, Peter W G Brown, Department of Radiology, Sheffield Teaching Hospitals NHS trust, Northern General Hospital, Sheffield S5 7AU, United - - 2014
To evaluate the referrals with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC) and compare cardiac MR (cMR) findings against clinical diagnosis. A retrospective analysis of 114 (age range 16 to 83, males 55% and females 45%) patients referred for cMR with a suspected diagnosis of ARVC between May 2006 and February ...
Rubino Sebastian S Geisel School of Medicine at Dartmouth, Hanover; - - 2014
Object Many neurosurgeons obtain repeat head CT at the first clinic follow-up visit for nonoperative cerebral contusion and traumatic subarachnoid hemorrhage (tSAH). The authors undertook a single-center, retrospective study to determine whether outpatient CT altered clinical decision-making. Methods The authors evaluated 173 consecutive adult patients admitted to their institution from ...
Zengin Mehmet Ozgur MO Department of Ophtalmology, Izmir University Faculty of Medicine, Gursel Aksel Bulvarı, No. 14, Uckuyular, 35350, Izmir, Turkey, - - 2014
To evaluate the choroidal thickness using spectral-domain optical coherence tomography (OCT) in patients with pseudoexfoliation syndrome (PXS) and to compare them with healthy controls. This observational comparative study consisted of 35 PXS patients and 35 age- and sex-matched control cases. The control cases had neither systemic nor ocular disease. All ...
Pimienta Allen L AL Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, - - 2014
The presence of cardiovascular abnormalities in patients with spontaneous cerebrospinal fluid (CSF) leaks are not well-documented in the literature, as cardiovascular evaluation is not generally pursued if a patient does not exhibit additional clinical features suggesting an inherited connective tissue disorder. We aimed to assess this association, enrolling a consecutive ...
Pastor Andrés García AG Stroke Unit, Neurology Department, Hospital General Universitario Gregorio Marañón, Madrid, - - 2014
Vascular imaging is increasingly used for diagnosis of arterial occlusions in acute ischemic stroke (AIS) patients. Our aim was to determine whether computed tomography angiography (CTA) and Doppler/duplex ultrasound (DUS) before intravenous thrombolysis (IVT) is associated with a delay in time-to-treatment. Observational analysis of a prospective cohort of AIS patients ...
Ding Liang L Central Laboratory of Stomatology, Hospital of Stomatology, and the State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, People's Republic of - - 2014
Monocyte chemotactic protein-1 (MCP-1/CCL2) and macrophage inflammatory protein-1α (MIP-1α/CCL3) are small chemotactic proteins that have been found in several kinds of tumor tissue samples and function as key regulators of cancer progression. However, the expression of CCL2 and CCL3 in serum samples of oral squamous cell carcinoma (OSCC) patients remains ...
Freyvogel Mary M Breast Services, Cleveland Clinic Foundation, Cleveland, USA, - - 2014
Currently, no standard guidelines exist regarding routine screening imaging in breast cancer patients following autologous reconstruction. Concern over nonpalpable chest wall recurrence has prompted many to pursue screening imaging. We analyzed the pattern of locoregional recurrence (LRR) and yield of screening imaging and exam in these patients. We performed a ...
Liu Zhenyin Z Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, - - 2014
The aim of this study is to explore the possible changed cerebral white matter regions in patients with temporal lobe epilepsy (TLE) using diffusion tensor imaging (DTI) and tract-based spatial statistics (TBSS). Twenty TLE patients and 22 age- and gender-matched normal controls were included in this study. Voxel-wise analyses of ...
Applewhite Megan K MK Department of General Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA; Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, Wisconsin, - - 2014
The biochemical profile of classic primary hyperparathyroidism (pHPT) consists of both elevated calcium and parathyroid hormone levels. The standard of care is parathyroidectomy unless prohibited by medical comorbidities. Because more patients are undergoing routine bone density evaluation and neck imaging studies for other purposes, there is a subset of people ...
Palmieri Arianna A Department of Neurosciences, University of Padova, Padova, Italy Department of Philosophy, Sociology, Pedagogy and Applied Psychology (FISPPA), University of Padova, Padova, - - 2014
Cognitive impairment, mainly characterised by executive dysfunction, occurs in about half of cases in amyotrophic lateral sclerosis (ALS). There is evidence that gender influences some clinical features of the disease, but its influence on the cognitive spectrum is unknown. Our objective was to investigate the impact of gender on cognitive ...
Vayá Amparo A Hemorheology and Haemostasis Unit, Service of Clinical Pathology, La Fe University Hospital, Valencia, - - 2014
Increased red blood distribution width (RDW) in anemia is related to disturbances in the cellular surface/volume ratio, usually accompanied by morphological alterations, while it has been shown in inflammatory diseases that the activity of pro-inflammatory cytokines disturbing erythropoiesis increases RDW. Recently it has been reported that higher RDW is related ...
Tsirakis George - - 2014
Objective Interleukin-22 (IL-22) is a cytokine participating in many aspects of inflammation. Multiple myeloma (MM) is a malignant disease of plasma cells with characteristic immune deregulation. We estimated serum levels of IL-22 in MM patients, both in activity and remission, in order to apprehend its possible participation in MM biology. ...
Oride A A Department of Obstetrics and Gynecology, Shimane University School of Medicine , Shimane Prefecture , - - 2014
This study aimed to determine the effectiveness of human menopausal gonadotropin (hMG) with and without clomiphene citrate (CC) for ovarian stimulation and oocyte retrieval in poor-responders. A total of 66 cycles in 13 patients met the inclusion criteria of 20 cycles of hMG stimulation and 46 cycles of CC + ...
Nassar Khaled K Department of Ophthalmology, University of Luebeck, Ratzeburger Allee 160, D-23538, Luebeck, Germany, - - 2014
This study evaluates the potential of serum pro-inflammatory cytokines as AMD biomarkers. Serum samples from 30 age-related macular degeneration (AMD) patients and 15 age-matched controls were examined for 16 inflammatory cytokines using multiplex ELISA. Patients were divided into three subgroups (improvement/no change/deterioration during anti-VEGF treatment) by OCT and funduscopy, and ...
Kulkantrakorn Kongkiat K Neurology Division, Department of Internal Medicine, Thammasat University, Rangsit Campus, Pathumthani, 12120, Thailand, - - 2014
High dose pyridoxine is neurotoxic. Previous case reports were sparse and little is known about the clinical and electrodiagnostic findings. Three patients with pyridoxine-induced sensory ataxic neuropathy were studied and a review of the involved literature was performed. Three patients, aged 80, 83 and 83 years old, presented with sensory ataxia ...
Yoshitomi Ryota R Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
The ankle-brachial blood pressure index (ABPI) has been recognized to have a predictive value for cardiovascular (CV) events and mortality in general or dialysis populations. However, the associations between ABPI and those outcomes have not been fully investigated in predialysis patients. The present study aimed to clarify the relationships between ...
Witkowski Grzegorz G 1st Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957, Warsaw, Poland, - - 2014
The DWI/FLAIR mismatch is a potential radiological marker for the timing of stroke onset. The aim of the study was to assess if the DWI/FLAIR mismatch can help to identify patients with both lacunar and nonlacunar acute ischemic stroke within 4.5 h of onset. A retrospective study was performed in which ...
Linquist Rebecca A RA Oculofacial Plastic and Orbital Surgery, Department of Ophthalmology, KU Eye, University of Kansas , Prairie Village, Kansas , USA - - 2014
Abstract Purpose: To examine the association of cytokines in the two clinical subtypes of ophthalmic Graves' disease by comparing cytokine expression in the fat and ethmoid tissue of type I and type II patients. Methods: Patients needing orbital decompression or eyelid surgery were identified and enrolled into a prospective study. ...
Lima Luciene Terezina de - - 2014
Background Genetic variations in membrane transporters may contribute to imatinib mesylate (IM) resistance in chronic myeloid leukemia (CML). Objective To investigate the relationship between SLCO1B3, SLCO1A2, and ABCA3 polymorphisms and IM response in CML patients. Methods Patients in chronic phase CML (N = 118) were studied. All patients were treated with a ...
Bartur Gadi G Reuth Rehabilitation Center, Tel Aviv, - - 2014
The objective of this study is to assess the autonomic nerve heart rate regulation system at rest and its immediate response to paced breathing among patients with complex regional pain syndrome (CRPS) as compared with age-matched healthy controls. Quasiexperimental. Outpatient clinic. Ten patients with CRPS and 10 age- and sex-matched ...
Bernardez-Pereira Sabrina - - 2014
Previous studies have shown the occurrence of actinin-3 deficiency in the presence of the R577X polymorphism in the ACTN3 gene. Our hypothesis is that this deficiency, by interfering with the function of skeletal muscle fiber, can result in a worse prognosis in patients with chronic heart failure. A prospective cohort ...
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