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Di Fabio R - - 2014
To date, there exist no data reporting the level of suitability of requests for electromyography examinations (EMGs) in Rome. The records of 1,220 consecutive patients (age: 57.6±15.0 years; 400 M, 820 F) in two neurophysiology laboratories were collected and analyzed. In total, 1,317 EMGs were requested, mainly by general practitioners ...
Thonnard M - - 2014
Zolpidem has been reported as an "awakening drug" in some patients with disorders of consciousness (DOC). We here present the results of a prospective openlabel study in chronic DOC patients. Sixty patients (35±15 years; 18 females; mean time since insult ± SD: 4±5.5 years; 31 with traumatic etiology) with a ...
Mohamad Yadzir Zailatul Hani ZH Allergy and Immunology Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia. - - 2014
Component-resolved diagnosis (CRD) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. The aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (SPT).45 patients with allergic rhinitis were studied (16 children and ...
Mortazavi Hossein H Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran and Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
Pemphigus vulgaris is an autoimmune disease, in which the role of Th17 cytokines needs to be further explored. This study was performed to assess serum levels of three interleukins (IL) required for Th17 differentiation (IL-1β, IL-6 and IL-23) and two specific Th17 cytokines (IL-17 and IL-22) in a group of ...
Shakiba Yadollah Y Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
In this study we determined the frequency, sensitivity and specificity of anti cyclic citrullinated peptides (anti-CCP) IgG antibody, total rheumatoid factor (RF-T), and RF isotypes in Iranian patients with rheumatoid arthritis (RA) and their association with age, clinical and serological parameters. Anti-CCP and RF-T and RF isotypes level were measured ...
Unubol M M Division of Endocrinology Department of Internal Medicine Adnan Menderes University Medical Faculty Aydin, Turkey - - - 2014
There remains conflicting opinions regarding the relationship between the risk of cardiovascular disease and subclinical hypothyroidism (SH), and there are also varying study results. Recent growing evidence suggests that epicardial adipose tissue (EAT) may play a key role in the pathogenesis and development of coronary artery disease. The effects of ...
Koch David G DG Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of South Carolina, 25 Courtenay Drive ART 7100A, MSC 290, Charleston, SC 29425, USA. Electronic address: - - 2014
The hepatopulmonary syndrome (HPS) is a pulmonary complication of cirrhosis and/or portal hypertension whereby patients develop hypoxemia as a result of alterations in pulmonary microvascular tone and architecture. HPS occurs in up to 30% of patients with cirrhosis. Although the degree of hypoxemia does not reliably correlate with the severity ...
Henry Zachary Z Division of Gastroenterology and Hepatology, University of Virginia Health System, PO Box 800708, Charlottesville, VA 22908-0708, - - 2014
Although often considered together, gastric and ectopic varices represent complications of a heterogeneous group of underlying diseases. Commonly, these are known to arise in patients with cirrhosis secondary to portal hypertension; however, they also arise in patients with noncirrhotic portal hypertension, most often secondary to venous thrombosis of the portal ...
Choi Sun A SA Department of Otorhinolaryngology, Kyung Hee University School of Medicine , Seoul , - - 2014
Abstract Conclusion: Facial nerve dehiscence (FND) and ossicular injury occurred more frequently in patients with cholesteatomatous than non-cholesteatomatous otitis media. Objective: FND and ossicular injury commonly occur intraoperatively in patients with otitis media, both with and without cholesteatoma. This study was designed to analyze differences in FND and ossicular injury ...
Perez-Fernandez Nicolas N Department of Otorhinolaryngology, Clinica Universidad de Navarra, University of Navarra , Pamplona , - - 2014
Abstract Conclusion: The function of all the semicircular canals in patients with idiopathic benign paroxysmal positional vertigo (BPPV) in whom otoconial debris is located in the superior semicircular canal (SSC) is normal. Objective: BPPV of SSC is an infrequent entity in which otoconial debris evokes vertigo and nystagmus in the ...
Bisceglia Michele M *IRCCS, Referral Cancer Center of Basilicata #IRCCS, Unit of Medical Oncology, Referral Cancer Center of Basilicata, Rionero in Vulture (PZ) ‡Department of Pathology and Laboratory Medicine, "S. Maria della Misericordia" General Hospital, Udine ∥Department of Radiology ¶Gynecology and Obstetrics Division, IRCCS "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo (FG), Italy †Anatomic Pathology Department, Cook's Children Medical Center, Fort Worth, TX §Department of Pathology, The Barzilai Medical Center, Ashkelon, - - 2014
We present the clinicopathologic features of 3 cases of leiomyomatosis peritonealis disseminata (LPD). The patients were 33, 34, and 41 years old at the time of diagnoses. The 3 women had undergone laparoscopic removal of multiple uterine leiomyomas between 1 and 6 years before the diagnoses of LPD. Laparoscopic uterine ...
Kobayashi Go G From the *Department of Gastroenterology, Sendai City Medical Center, Sendai; †Center for Gastroenterology, Teine-Keijinkai Hospital, Sapporo; ‡Department of General Medicine, Asahikawa Medical College, Asahikawa; §Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya; ∥Center for Gastroendoscopy, Onomichi General Hospital, Hiroshima; ¶Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo; #Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka; **Department of Gastroenterology, Chiba Cancer Center, Chiba; ††Department of Gastroenterological Surgery, Tokai University School of Medicine, Kanagawa; ‡‡Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University; and §§Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, - - 2014
This study aimed to elucidate the natural history of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with mural nodules (MNs) in branch duct IPMN (BD-IPMN). Among the 402 registered patients with BD-IPMN on long-term follow-up at 10 institutions in Japan, 53 patients with MNs of less than 10 mm ...
Van Gent Jan-Michael JM From the Trauma Service, Scripps Mercy Hospital, San Diego, - - 2014
Pulmonary embolus (PE) is thought to arise from a deep venous thrombosis (DVT). Recent data suggest that PE can present without DVT, inferring that PE can originate de novo (DNPE). We examined the relationship between DVT and PE in trauma patients screened for DVT with duplex sonography (DS). We sought ...
Verbeek Diederik O F DO From the Trauma Unit, Department of Surgery (D.O.F.V., K.J.P., J.C.G.), and Department of Radiology (I.A.J.Z., C.V.D.L., O.M.V.D.), Academic Medical Center (AMC), University of Amsterdam (UvA), Amsterdam, the - - 2014
In our institution, the computed tomographic (CT) scan has largely replaced the ultrasound for the rapid detection of intraperitoneal free fluid (FF) and abdominal injuries in severely injured patients.We hypothesized that in major pelvic fracture patients, quantifying the size of FF on CT improves the predictive value for the need ...
Sasson Talia T Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Box 648, Rochester, NY 14642. Electronic address: - - 2014
Patients who receive a left ventricular assist device (LVAD) are prone to develop end-stage renal disease. Primary arteriovenous fistula (AVF) maturation in these patients may be unsuccessful secondary to the nonpulsatile flow with an LVAD. Two patients with LVADs are described in whom assisted maturation aided long-term AVF patency.
Candan Ferhan F Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Cumhuriyet University, 58140, Sivas, - - 2014
Vascular access is vital for hemodialysis patients. A major factor that facilitates arteriovenous (AV) fistula failure is stenosis and thrombosis due to intimal hyperplasia developing in the venous segment of AV fistula. It has been reported that VEGF accelerated re-endothelialization, reduction in intimal thickening, and/or mural thrombus formed in the ...
Yousef Nida N Advocate Children's Hospital Heart Institute, 4440 West 95th Street, Oak Lawn, IL, 60453, USA, - - 2014
Transesophageal echocardiography (TEE) is used in atrial flutter or fibrillation (AFF) before electric cardioversion to detect intracardiac thrombi. Previous studies have described the use of TEE to diagnose intracardiac thrombi in the left atrium and left atrial appendage, which has an incidence of 8 % among patients without congenital heart disease ...
Ersöz Murat M Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey, - - 2014
In this study the possible preventive effect of bladder-filling sensation (BFS) on upper urinary tract deterioration (UUTD) in spinal cord injury (SCI) patients was investigated. Eighty-four (60 males, 24 females) patients with SCI who underwent neurourological assessment and urodynamic examinations because of neurogenic lower urinary tract dysfunction and were prescribed ...
Ates Fehmi F Division of Gastroenterology, Hepatology, and Nutrition, Center for Swallowing and Esophageal Disorders, Vanderbilt University Medical Center, C2104-MCN, Nashville, TN, - - 2014
'Refractory gastroesophageal reflux disease' is one of the most common misnomers in the area of gastroesophageal reflux disease. The term implies reflux as the underlying etiology despite unresponsiveness to aggressive proton pump inhibitor therapy. The term should be replaced with 'refractory symptoms.' We must acknowledge that in many patients symptoms ...
Cote Jonida J Department of Rheumatology, Geisinger Medical Center, 100 N Academy Ave, Danville, PA, 17821, USA, - - 2014
To evaluate the association of vitamin D level with incident rheumatoid arthritis (RA) in a patient population using electronic health records (EHR). Case-control study with data extracted from EHR from 1/1/2001 to 12/31/2012 in the Geisinger Health System (GHS). Incident RA was defined as International Classification of Disease-9 code 714.0 ...
Wang Z L ZL Renal Division, Huangdao Branch, Affiliated Hospital of Medical College, Qingdao University, Shandong Qingdao 266555, - - 2014
To investigate the clinical significance of peptidylarginine deiminase type 4 (PAD4) in the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). To make a primary observation on the relationship of chronic bronchitis and bronchiectasis (CB) with the pathogenesis of AAV by PAD4. The sera from 13 patients with AAV, 13 ...
Brandner Sebastian S Department of Neurosurgery, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, - - 2014
Background: Little information is available on the rostro-caudal concentration gradient of Alzheimer's disease (AD) biomarkers. Objective: We studied the concentrations of amyloid-β (Aβ) peptides 1-42 and 1-40 as well as the Tau and pTau proteins in simultaneously collected ventricular and lumbar cerebrospinal fluid (CSF) samples. Methods: The samples were simultaneously ...
Thomas Lisa E LE Department of Emergency Medicine, University of Maryland Upper Chesapeake Medical Center, Bel Air, - - 2014
Object When patients present to the emergency department (ED) with acute headache concerning for subarachnoid hemorrhage (SAH) and a lumbar puncture (LP) shows blood in the CSF, it is difficult to distinguish the results of a traumatic LP from those of SAH. CT angiography (CTA) is often performed, but the ...
Minami Seigo - - 2014
It remains unknown whether desaturation profiles during daily living are associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). Point measurements of resting oxygen saturation by pulse oximetry (SpO2) and partial pressure of arterial oxygen (PaO2) are not sufficient for assessment of desaturation during activities of daily living. ...
Ariyasu Hiroyuki H Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto 606-8507, - - 2014
The majority of patients with systemic sclerosis (SSc) have gastrointestinal (GI) tract involvement, but therapies using prokinetic agents are usually unsatisfactory. Ghrelin stimulates gastric motility in healthy human volunteers. In this study, we investigated whether ghrelin could improve gastric emptying in patients with gastrointestinal symptoms due to SSc. The study ...
Bowen Deborah A - - 2014
Abstract The differential diagnosis of rapidly progressive or symptomatic lymphadenopathy in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) includes infectious lymphadenitis. We studied 286 (9%) of 3040 CLL patients seen between 2003-2012 at Mayo Clinic Rochester who had 356 diagnostic lymph node biopsies to evaluate rapidly progressive or symptomatic ...
Peolsson Anneli A Guest Researcher, NHMRC CCRE (Spinal Pain, Injury and Health), The University of Queensland, Brisbane, Australia; Associate Professor, Department of Medical and Health Sciences, Physiotherapy, Faculty of Health Sciences, Linköping University, Linköping, Sweden. Electronic address: - - 2014
The purposes of this study were to examine whether any differences in function and health exist between patients with cervical radiculopathy (CR) due to disk disease scheduled for surgery and patients with chronic whiplash-associated disorders (WADs) and to compare measures of patients' physical function with those obtained from healthy volunteers. ...
Donate-Correa J - - 2014
In chronic kidney disease patients, active vitamin D level progressively declines in the course of the disease. This phenomenon is accompanied by elevations in parathyroid hormone, resulting in secondary hyperparathyroidism (SHPT), and phosphorous levels and hypocalcemia. All these disorders are associated with the high rate of cardiovascular morbidity and mortality ...
Suzuki Jun-Ichi JI Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan, - - 2014
Although there is a link between periodontitis and cardiovascular disease (CVD), the influence of periodontitis on CVD is unclear. The aim of this study was to assess the relationship between periodontal bacterial burden and CVD. We studied 142 patients with tachyarrhythmia (TA) and 25 patients with abdominal aortic aneurysm (AAA). ...
Kasai Takashi T Department of Neurology, Research Institute for Geriatrics, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan, - - 2014
Recent studies have shown that cerebrospinal fluid (CSF) levels of α-synuclein (α-syn) are highly elevated in patients with Creutzfeldt-Jakob disease (CJD) compared to controls. However, the diagnostic value of CSF α-syn in CJD has not been established. To confirm whether CSF α-syn is increased in CJD and is a useful ...
Zhu Bin B Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine (Guangxing Hospital), Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China, - - 2014
To investigate urinary nephrin and podocalyxin standardized by aquaporin (AQP)-2 using the enzyme-linked immunosorbent assay (ELISA) method in adult nephrotic syndrome (NS) patients. In 107 adult NS patients (27 proliferative nephritis, 77 non-proliferative, and 3 amyloidosis) undergoing renal biopsy, urinary nephrin, podocalyxin and AQP2 were measured by ELISA. Urinary nephrin ...
Chalmers James D JD Tayside Respiratory Research Group, University of Dundee, Dundee, UK, - - 2014
Mannose binding lectin (MBL) and ficolins contribute to host defence through activation of the lectin pathway of complement. In this study, serum levels of ficolin-2 and MBL were determined in 276 patients with community-acquired pneumonia (CAP). MBL deficiency and ficolin-2 insufficiency were defined using previously validated cut-offs. No differences were ...
Sulahian Annie A Université Paris Diderot, Sorbonne Paris-Cité, Laboratoire de Parasitologie-Mycologie, AP-HP, Hôpital Saint-Louis, Paris, - - 2014
This study was undertaken to examine the performance of the Fungitell® β-glucan assay (BG), compare it to that of the galactomannan (GM) test for the diagnosis of invasive aspergillosis (IA) in patients with hematologic malignancies and then to examine the respective rate of false positive BG and GM results due ...
Barbanti Marco M St. Paul's Hospital, University of British Columbia, Vancouver, - - 2014
Objectives: Significant tricuspid regurgitation (TR) is a marker for late-stage myocardial and valvular heart disease. Whether preoperative TR affects clinical outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) has never been investigated. This study sought to identify the impact of moderate and severe TR on outcomes after TAVR. Methods: ...
Calò Lorenzo A LA Department of Medicine (DIMED), University of Padova, - - 2014
Both increased and decreased levels of the adipokine Retinol-binding protein 4 (RBP4) have been reported in cardiovascular disease, and levels of RBP4 have been related to diabetes, metabolic syndrome and cardiovascular risk. Recently clear in vitro and ex vivo vasodilatory and inhibitory of platelet activation effects of RBP4 has been ...
Jiang Meng M State Key Laboratory of Oral Diseases and Department of Oral Radiology, West China Hospital of Stomatology, Sichuan University, Chengdu, - - 2014
This study was performed to analyze features of nasal septal deviation of patients with different cleft types and noncleft controls. Case-control study. West China Hospital of Stomatology, Chengdu, China. Sixty-six patients with palatal and/or alveolar cleft and 42 noncleft controls were recruited in the study. All the subjects have undergone ...
de Deus Chaves Rosane - - 2014
Breathing and swallowing are physiologically linked to ensure effortless gas exchange during oronasal breathing and to prevent aspiration during swallowing. Studies have indicated consistent aspiration in chronic obstructive pulmonary disease, mainly related to delayed swallowing reflex and problems with lingual propulsion and pharyngeal peristalsis as a result of bilateral weakness ...
Zimmer P - - 2014
ABSTRACT To assess the effects of chemoimmunotherapy on post chemotherapy cognitive impairments (PCCI) in B-cell Non-Hodgkin-Lymphoma (NHL) patients, we used objective and subjective measures of cognitive functions in combination with serum parameters and neuroelectric recordings. Self-perceived status of cognition, fatigue and emotional functioning were reduced in patients (n=30) compared to ...
Rey Johannes Wilhelm JW Johannes Wilhelm Rey, Katja Kramer, Peter Robert Galle, Martin Goetz, Marcus Schuchmann, Ralf Kiesslich, Arthur Hoffman, Department of Internal Medicine I, University Medical Center, 55131 Mainz, - - 2014
To evaluate the diagnostic yield (inflammatory activity) and efficiency (size of the biopsy specimen) of SpyGlass(TM)-guided biopsy vs standard brush cytology in patients with and without primary sclerosing cholangitis (PSC). At the University Medical Center Mainz, Germany, 35 consecutive patients with unclear biliary lesions (16 patients) or long-standing PSC (19 ...
Takeda Yoko Y Department of Pediatrics, Todaiji Medical and Education Center, Nara, - - 2014
Background: Carnitine plays a pivotal role in a variety of cellular functions. Carnitine deficiency often occurs in severely disabled patients, especially under valproic acid administration. However, the possible causative factors underlying carnitine deficiency have not been fully identified. The present study aimed at clarifying the association of various anthropometric and ...
Li Tianran - - 2014
Reports in Asian populations suggest that ethnic and geographical differences may influence susceptibility to multiple sclerosis (MS) and its clinical behaviors. Here, we sought to retrospectively survey clinical characteristics and MRI data in Chinese subjects with MS. We conducted a retrospective analysis in 117 patients with MS. The patients were ...
Wegner Małgorzata - - 2014
INTRODUCTION One of the reasons of impaired antioxidant response in patients with type 1 diabetes (DM1) could be decreased expression of mitochondrial superoxide dismutase (MnSOD). OBJECTIVES The purpose of this study was to evaluate expression of MnSOD at both transcript and protein level in polymorphonuclear leukocytes (PMNLs) from DM1 patients and analyzed ...
Chen Yu-Li YL Division of Endocrinology and Metabolism (Y.-L.C., C.-W.C., C.-Y.Y., K.-J.T.), Department of Internal Medicine, and Department of Medical Research (S.-F.W., J.-J.W.), Chi Mei Medical Center, Tainan 710, Taiwan; Department of Hospital and Health Care Administration (S.-F.W.) and The Center of General Education (K.-J.T.), Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan; and Department of Urology (Y.-C.S.), Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 807, - - 2014
Background: Obstructive sleep apnea (OSA) is associated with metabolic, endocrine, and cardiovascular diseases. It is characterized by repetitive episodes of apnea/hypopnea and hypoxia in tissues, which might also impact bone metabolism. This study investigates the possible association between OSA and osteoporosis. Methods: Random samples of 1 million individuals were collected ...
Ortiz Sergio S Servicio de Cirugía General y Digestiva (S.O., J.L.E., P.E., M.R., F.L.), Servicio de Farmacología Clínica (P.Z.), and Servicio de Endocrinología (A.A.), Hospital General Universitario de Alicante, Alicante, Spain; CIBERehd (P.Z., J.S., R.F.), Instituto de Salud Carlos III, Madrid, Spain; and Departamento de Medicina Clínica (P.Z., J.S., R.F.), Universidad Miguel Hernández, San Juan de Alicante, - - 2014
Background: Morbidly obese patients show several common comorbidities associated with immunological alterations such as a sustained low-level proinflammatory profile. Bacterial product translocation is frequent in inflammation-related diseases and may aggravate patients' clinical outcome. Design: Consecutively admitted morbidly obese patients who presented indications for bariatric surgery were studied. Before surgery, patients ...
Andersson Mikael M 1Department of Neuroscience, Physiotherapy, Uppsala University , Uppsala , - - 2014
Abstract Low physical activity and sedentary behaviour characterise the lives of patients with chronic obstructive pulmonary disease (COPD). Using activity monitors, assessment of both aspects are possible, but many outcomes are not well validated. The aim of this study was to assess the accuracy and equivalency of three activity monitors ...
Endo Akiko A From the Nephrology Center and Okinaka Memorial Institute for Medical Research, Department of Pathology, and Nephrology Center, Toranomon Hospital; Division of Nephrology, Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, - - 2014
Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is a vasculitis affecting the glomerular capillaries and small renal arteries. Although crescent formation has been reported to be characteristic of this condition, the significance of coexisting vasculitis affecting the small renal arteries has not been investigated. Fifty patients with ANCA-positive rapidly progressive glomerulonephritis whose ...
Aksoy F F Department of Otorhinolaryngology, Bezmiâlem Vakif University, Istanbul, - - 2014
Objective: We aimed to identify the role of major respiratory viruses in the aetiology of human nasal polyps using polymerase chain reaction technique. Methods: Thirty patients with nasal polyps and a group of 20 healthy patients (control group) were included in this study. Mucosa was obtained from the polyps of ...
Schuller Wouter - - 2014
Reported values of the minimal important change (MIC) and the smallest detectable change (SDC) for the neck disability index (NDI) differ strongly, raising questions about the generalizability of these parameters. The SDC and the MIC are possibly influenced by the study design or by the study population. We studied the ...
Nguyen Liem L Department of Anesthesiology, Division of Cardiothoracic Anesthesiology. Electronic address: - - 2014
Patients with left-sided heart dysfunction and volume overload often have associated elevations in vasopressin from neuroendocrine activation. The authors investigated perioperative levels of vasopressin in patients with isolated right-sided heart dysfunction from chronic thromboembolic pulmonary hypertension. Prospective, observational study. Single center, tertiary hospital. Patients with chronic thromboembolic pulmonary hypertension undergoing ...
Zhang Jian-Jun JJ Department of Hepatology, Qilu Hospital of Shandong University, Ji'nan, - - 2014
Suppressor of cytokine signaling (SOCS) 1 plays a crucial role in the immune response and might contribute to the prognoses of liver failure treated with glucocorticoid. We recruited 47 acute-on-chronic hepatitis B liver failure (ACHBLF) patients receiving glucocorticoid treatment and 30 healthy controls to determine the potential effects of glucocorticoid ...
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