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Di Fabio R - - 2014
To date, there exist no data reporting the level of suitability of requests for electromyography examinations (EMGs) in Rome. The records of 1,220 consecutive patients (age: 57.6±15.0 years; 400 M, 820 F) in two neurophysiology laboratories were collected and analyzed. In total, 1,317 EMGs were requested, mainly by general practitioners ...
Thonnard M - - 2014
Zolpidem has been reported as an "awakening drug" in some patients with disorders of consciousness (DOC). We here present the results of a prospective openlabel study in chronic DOC patients. Sixty patients (35±15 years; 18 females; mean time since insult ± SD: 4±5.5 years; 31 with traumatic etiology) with a ...
Mohamad Yadzir Zailatul Hani ZH Allergy and Immunology Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia. - - 2014
Component-resolved diagnosis (CRD) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. The aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (SPT).45 patients with allergic rhinitis were studied (16 children and ...
Mortazavi Hossein H Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran and Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
Pemphigus vulgaris is an autoimmune disease, in which the role of Th17 cytokines needs to be further explored. This study was performed to assess serum levels of three interleukins (IL) required for Th17 differentiation (IL-1β, IL-6 and IL-23) and two specific Th17 cytokines (IL-17 and IL-22) in a group of ...
Shakiba Yadollah Y Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
In this study we determined the frequency, sensitivity and specificity of anti cyclic citrullinated peptides (anti-CCP) IgG antibody, total rheumatoid factor (RF-T), and RF isotypes in Iranian patients with rheumatoid arthritis (RA) and their association with age, clinical and serological parameters. Anti-CCP and RF-T and RF isotypes level were measured ...
Unubol M M Division of Endocrinology Department of Internal Medicine Adnan Menderes University Medical Faculty Aydin, Turkey - - - 2014
There remains conflicting opinions regarding the relationship between the risk of cardiovascular disease and subclinical hypothyroidism (SH), and there are also varying study results. Recent growing evidence suggests that epicardial adipose tissue (EAT) may play a key role in the pathogenesis and development of coronary artery disease. The effects of ...
Koch David G DG Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of South Carolina, 25 Courtenay Drive ART 7100A, MSC 290, Charleston, SC 29425, USA. Electronic address: - - 2014
The hepatopulmonary syndrome (HPS) is a pulmonary complication of cirrhosis and/or portal hypertension whereby patients develop hypoxemia as a result of alterations in pulmonary microvascular tone and architecture. HPS occurs in up to 30% of patients with cirrhosis. Although the degree of hypoxemia does not reliably correlate with the severity ...
Henry Zachary Z Division of Gastroenterology and Hepatology, University of Virginia Health System, PO Box 800708, Charlottesville, VA 22908-0708, - - 2014
Although often considered together, gastric and ectopic varices represent complications of a heterogeneous group of underlying diseases. Commonly, these are known to arise in patients with cirrhosis secondary to portal hypertension; however, they also arise in patients with noncirrhotic portal hypertension, most often secondary to venous thrombosis of the portal ...
Choi Sun A SA Department of Otorhinolaryngology, Kyung Hee University School of Medicine , Seoul , - - 2014
Abstract Conclusion: Facial nerve dehiscence (FND) and ossicular injury occurred more frequently in patients with cholesteatomatous than non-cholesteatomatous otitis media. Objective: FND and ossicular injury commonly occur intraoperatively in patients with otitis media, both with and without cholesteatoma. This study was designed to analyze differences in FND and ossicular injury ...
Perez-Fernandez Nicolas N Department of Otorhinolaryngology, Clinica Universidad de Navarra, University of Navarra , Pamplona , - - 2014
Abstract Conclusion: The function of all the semicircular canals in patients with idiopathic benign paroxysmal positional vertigo (BPPV) in whom otoconial debris is located in the superior semicircular canal (SSC) is normal. Objective: BPPV of SSC is an infrequent entity in which otoconial debris evokes vertigo and nystagmus in the ...
Bisceglia Michele M *IRCCS, Referral Cancer Center of Basilicata #IRCCS, Unit of Medical Oncology, Referral Cancer Center of Basilicata, Rionero in Vulture (PZ) ‡Department of Pathology and Laboratory Medicine, "S. Maria della Misericordia" General Hospital, Udine ∥Department of Radiology ¶Gynecology and Obstetrics Division, IRCCS "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo (FG), Italy †Anatomic Pathology Department, Cook's Children Medical Center, Fort Worth, TX §Department of Pathology, The Barzilai Medical Center, Ashkelon, - - 2014
We present the clinicopathologic features of 3 cases of leiomyomatosis peritonealis disseminata (LPD). The patients were 33, 34, and 41 years old at the time of diagnoses. The 3 women had undergone laparoscopic removal of multiple uterine leiomyomas between 1 and 6 years before the diagnoses of LPD. Laparoscopic uterine ...
Kobayashi Go G From the *Department of Gastroenterology, Sendai City Medical Center, Sendai; †Center for Gastroenterology, Teine-Keijinkai Hospital, Sapporo; ‡Department of General Medicine, Asahikawa Medical College, Asahikawa; §Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya; ∥Center for Gastroendoscopy, Onomichi General Hospital, Hiroshima; ¶Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo; #Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka; **Department of Gastroenterology, Chiba Cancer Center, Chiba; ††Department of Gastroenterological Surgery, Tokai University School of Medicine, Kanagawa; ‡‡Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University; and §§Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, - - 2014
This study aimed to elucidate the natural history of intraductal papillary mucinous neoplasm (IPMN) of the pancreas with mural nodules (MNs) in branch duct IPMN (BD-IPMN). Among the 402 registered patients with BD-IPMN on long-term follow-up at 10 institutions in Japan, 53 patients with MNs of less than 10 mm ...
Wang Z L ZL Renal Division, Huangdao Branch, Affiliated Hospital of Medical College, Qingdao University, Shandong Qingdao 266555, - - 2014
To investigate the clinical significance of peptidylarginine deiminase type 4 (PAD4) in the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). To make a primary observation on the relationship of chronic bronchitis and bronchiectasis (CB) with the pathogenesis of AAV by PAD4. The sera from 13 patients with AAV, 13 ...
Minami Seigo - - 2014
It remains unknown whether desaturation profiles during daily living are associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). Point measurements of resting oxygen saturation by pulse oximetry (SpO2) and partial pressure of arterial oxygen (PaO2) are not sufficient for assessment of desaturation during activities of daily living. ...
Ariyasu Hiroyuki H Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto 606-8507, - - 2014
The majority of patients with systemic sclerosis (SSc) have gastrointestinal (GI) tract involvement, but therapies using prokinetic agents are usually unsatisfactory. Ghrelin stimulates gastric motility in healthy human volunteers. In this study, we investigated whether ghrelin could improve gastric emptying in patients with gastrointestinal symptoms due to SSc. The study ...
Bowen Deborah A - - 2014
Abstract The differential diagnosis of rapidly progressive or symptomatic lymphadenopathy in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) includes infectious lymphadenitis. We studied 286 (9%) of 3040 CLL patients seen between 2003-2012 at Mayo Clinic Rochester who had 356 diagnostic lymph node biopsies to evaluate rapidly progressive or symptomatic ...
Suzuki Jun-Ichi JI Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan, - - 2014
Although there is a link between periodontitis and cardiovascular disease (CVD), the influence of periodontitis on CVD is unclear. The aim of this study was to assess the relationship between periodontal bacterial burden and CVD. We studied 142 patients with tachyarrhythmia (TA) and 25 patients with abdominal aortic aneurysm (AAA). ...
Kasai Takashi T Department of Neurology, Research Institute for Geriatrics, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan, - - 2014
Recent studies have shown that cerebrospinal fluid (CSF) levels of α-synuclein (α-syn) are highly elevated in patients with Creutzfeldt-Jakob disease (CJD) compared to controls. However, the diagnostic value of CSF α-syn in CJD has not been established. To confirm whether CSF α-syn is increased in CJD and is a useful ...
Zhu Bin B Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine (Guangxing Hospital), Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China, - - 2014
To investigate urinary nephrin and podocalyxin standardized by aquaporin (AQP)-2 using the enzyme-linked immunosorbent assay (ELISA) method in adult nephrotic syndrome (NS) patients. In 107 adult NS patients (27 proliferative nephritis, 77 non-proliferative, and 3 amyloidosis) undergoing renal biopsy, urinary nephrin, podocalyxin and AQP2 were measured by ELISA. Urinary nephrin ...
Chalmers James D JD Tayside Respiratory Research Group, University of Dundee, Dundee, UK, - - 2014
Mannose binding lectin (MBL) and ficolins contribute to host defence through activation of the lectin pathway of complement. In this study, serum levels of ficolin-2 and MBL were determined in 276 patients with community-acquired pneumonia (CAP). MBL deficiency and ficolin-2 insufficiency were defined using previously validated cut-offs. No differences were ...
Sulahian Annie A Université Paris Diderot, Sorbonne Paris-Cité, Laboratoire de Parasitologie-Mycologie, AP-HP, Hôpital Saint-Louis, Paris, - - 2014
This study was undertaken to examine the performance of the Fungitell® β-glucan assay (BG), compare it to that of the galactomannan (GM) test for the diagnosis of invasive aspergillosis (IA) in patients with hematologic malignancies and then to examine the respective rate of false positive BG and GM results due ...
Barbanti Marco M St. Paul's Hospital, University of British Columbia, Vancouver, - - 2014
Objectives: Significant tricuspid regurgitation (TR) is a marker for late-stage myocardial and valvular heart disease. Whether preoperative TR affects clinical outcomes of patients undergoing transcatheter aortic valve replacement (TAVR) has never been investigated. This study sought to identify the impact of moderate and severe TR on outcomes after TAVR. Methods: ...
Calò Lorenzo A LA Department of Medicine (DIMED), University of Padova, - - 2014
Both increased and decreased levels of the adipokine Retinol-binding protein 4 (RBP4) have been reported in cardiovascular disease, and levels of RBP4 have been related to diabetes, metabolic syndrome and cardiovascular risk. Recently clear in vitro and ex vivo vasodilatory and inhibitory of platelet activation effects of RBP4 has been ...
Jiang Meng M State Key Laboratory of Oral Diseases and Department of Oral Radiology, West China Hospital of Stomatology, Sichuan University, Chengdu, - - 2014
This study was performed to analyze features of nasal septal deviation of patients with different cleft types and noncleft controls. Case-control study. West China Hospital of Stomatology, Chengdu, China. Sixty-six patients with palatal and/or alveolar cleft and 42 noncleft controls were recruited in the study. All the subjects have undergone ...
de Deus Chaves Rosane - - 2014
Breathing and swallowing are physiologically linked to ensure effortless gas exchange during oronasal breathing and to prevent aspiration during swallowing. Studies have indicated consistent aspiration in chronic obstructive pulmonary disease, mainly related to delayed swallowing reflex and problems with lingual propulsion and pharyngeal peristalsis as a result of bilateral weakness ...
Zimmer P - - 2014
ABSTRACT To assess the effects of chemoimmunotherapy on post chemotherapy cognitive impairments (PCCI) in B-cell Non-Hodgkin-Lymphoma (NHL) patients, we used objective and subjective measures of cognitive functions in combination with serum parameters and neuroelectric recordings. Self-perceived status of cognition, fatigue and emotional functioning were reduced in patients (n=30) compared to ...
Li Tianran - - 2014
Reports in Asian populations suggest that ethnic and geographical differences may influence susceptibility to multiple sclerosis (MS) and its clinical behaviors. Here, we sought to retrospectively survey clinical characteristics and MRI data in Chinese subjects with MS. We conducted a retrospective analysis in 117 patients with MS. The patients were ...
Wegner MaƂgorzata - - 2014
INTRODUCTION One of the reasons of impaired antioxidant response in patients with type 1 diabetes (DM1) could be decreased expression of mitochondrial superoxide dismutase (MnSOD). OBJECTIVES The purpose of this study was to evaluate expression of MnSOD at both transcript and protein level in polymorphonuclear leukocytes (PMNLs) from DM1 patients and analyzed ...
Chen Yu-Li YL Division of Endocrinology and Metabolism (Y.-L.C., C.-W.C., C.-Y.Y., K.-J.T.), Department of Internal Medicine, and Department of Medical Research (S.-F.W., J.-J.W.), Chi Mei Medical Center, Tainan 710, Taiwan; Department of Hospital and Health Care Administration (S.-F.W.) and The Center of General Education (K.-J.T.), Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan; and Department of Urology (Y.-C.S.), Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 807, - - 2014
Background: Obstructive sleep apnea (OSA) is associated with metabolic, endocrine, and cardiovascular diseases. It is characterized by repetitive episodes of apnea/hypopnea and hypoxia in tissues, which might also impact bone metabolism. This study investigates the possible association between OSA and osteoporosis. Methods: Random samples of 1 million individuals were collected ...
Ortiz Sergio S Servicio de Cirugía General y Digestiva (S.O., J.L.E., P.E., M.R., F.L.), Servicio de Farmacología Clínica (P.Z.), and Servicio de Endocrinología (A.A.), Hospital General Universitario de Alicante, Alicante, Spain; CIBERehd (P.Z., J.S., R.F.), Instituto de Salud Carlos III, Madrid, Spain; and Departamento de Medicina Clínica (P.Z., J.S., R.F.), Universidad Miguel Hernández, San Juan de Alicante, - - 2014
Background: Morbidly obese patients show several common comorbidities associated with immunological alterations such as a sustained low-level proinflammatory profile. Bacterial product translocation is frequent in inflammation-related diseases and may aggravate patients' clinical outcome. Design: Consecutively admitted morbidly obese patients who presented indications for bariatric surgery were studied. Before surgery, patients ...
Andersson Mikael M 1Department of Neuroscience, Physiotherapy, Uppsala University , Uppsala , - - 2014
Abstract Low physical activity and sedentary behaviour characterise the lives of patients with chronic obstructive pulmonary disease (COPD). Using activity monitors, assessment of both aspects are possible, but many outcomes are not well validated. The aim of this study was to assess the accuracy and equivalency of three activity monitors ...
Endo Akiko A From the Nephrology Center and Okinaka Memorial Institute for Medical Research, Department of Pathology, and Nephrology Center, Toranomon Hospital; Division of Nephrology, Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, - - 2014
Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is a vasculitis affecting the glomerular capillaries and small renal arteries. Although crescent formation has been reported to be characteristic of this condition, the significance of coexisting vasculitis affecting the small renal arteries has not been investigated. Fifty patients with ANCA-positive rapidly progressive glomerulonephritis whose ...
Aksoy F F Department of Otorhinolaryngology, Bezmiâlem Vakif University, Istanbul, - - 2014
Objective: We aimed to identify the role of major respiratory viruses in the aetiology of human nasal polyps using polymerase chain reaction technique. Methods: Thirty patients with nasal polyps and a group of 20 healthy patients (control group) were included in this study. Mucosa was obtained from the polyps of ...
Schuller Wouter - - 2014
Reported values of the minimal important change (MIC) and the smallest detectable change (SDC) for the neck disability index (NDI) differ strongly, raising questions about the generalizability of these parameters. The SDC and the MIC are possibly influenced by the study design or by the study population. We studied the ...
Zhang Jian-Jun JJ Department of Hepatology, Qilu Hospital of Shandong University, Ji'nan, - - 2014
Suppressor of cytokine signaling (SOCS) 1 plays a crucial role in the immune response and might contribute to the prognoses of liver failure treated with glucocorticoid. We recruited 47 acute-on-chronic hepatitis B liver failure (ACHBLF) patients receiving glucocorticoid treatment and 30 healthy controls to determine the potential effects of glucocorticoid ...
Schutgens Roger E G RE Van Creveldkliniek, University Medical Center Utrecht, Utrecht, the - - 2014
Atrial fibrillation (AF) is a common health problem in the general population, but data on prevalence or management in patients with haemophilia (PWH) are lacking. The aims of this study were to analyse the prevalence of AF and risk factors for stroke using a cross-sectional pan-European design and to document ...
Stagi S S 1Health Sciences Department, University of Florence, Anna Meyer Children's University Hospital, Florence, - - 2014
Background Hypovitaminosis D is common in the general population. Although many studies on 25-hydroxyvitamin D (25(OH)D) are available on systemic lupus erythematosus (SLE), few data are reported in juvenile-onset SLE (JSLE) patients.DesignThis study aimed to assess serum 25(OH)D levels in JSLE patients and to identify risk factors for vitamin D ...
Sigler Eric J EJ *Division of Retina and Vitreous, Ophthalmic Consultants of Long Island, Lynbrook, New York; †Division of Vitreoretinal Surgery, Charles Retina Institute, Memphis, Tennessee; and ‡Division of Retina and Vitreous, Department of Ophthalmology, University of Tennessee School of Medicine, Memphis, - - 2014
To compare the spectral-domain optical coherence tomography morphologic features and visual characteristics of a series of patients with epimacular membrane with and without a history of retinal breaks. Prospective, comparative case series of patients with epimacular membrane. All patients were evaluated with spectral-domain optical coherence tomography and detailed peripheral retinal ...
Hoedemaker Reinier A RA Reinier A Hoedemaker, Jessie Westerhof, Rinse K Weersma, Jan J Koornstra, Department of Gastroenterology and Hepatology, University Medical Centre Groningen, University of Groningen, 9700 RB Groningen, The - - 2014
To investigate the incidence of non-small-bowel abnormalities in patients referred for small bowel capsule endoscopy, this single center study was performed. Small bowel capsule endoscopy is an accepted technique to investigate obscure gastrointestinal bleeding. This is defined as bleeding from the digestive tract that persists or recurs without an obvious ...
Yin De-Chun - - 2014
This study is aimed to evaluate the clinical significance of heart rate turbulence (HRT) parameters in predicting the prognosis in patients with chronic heart failure (CHF). From June 2011 to December 2012, a total of 104 CHF patients and 30 healthy controls were enrolled in this study. We obtained a ...
Cherubini Andrea A Neuroimaging Research Unit, Institute of Molecular Bioimaging and Physiology-National Research Council, Catanzaro, - - 2014
The aim of the current study was to distinguish patients who had tremor-dominant Parkinson's disease (tPD) from those who had essential tremor with rest tremor (rET). We combined voxel-based morphometry-derived gray matter and white matter volumes and diffusion tensor imaging-derived mean diffusivity and fractional anisotropy in a support vector machine ...
Huang Yang-Yang YY Department of Neurology, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, - - 2014
The present study aimed to determine lesion patterns and the stroke mechanisms in cryptogenic ischemic stroke patients with patent foramen ovale (PFO) on T2-weighted magnetic resonance imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) sequences combined. In this retrospective study, 38 patients with cryptogenic stroke and an isolated PFO compared with ...
Overgaard Karsten K Department of Neurology, University Hospital of Copenhagen, Herlev Hospital, Herlev, Denmark. Electronic address: - - 2014
Early reopening of the occluded artery is, thus, important in ischemic stroke, and it has been calculated that 2 million neurons die every minute in an ischemic stroke if no effective therapy is given; therefore, "Time is Brain." In massive hemispheric infarction and edema, surgical decompression lowers the risk of ...
Bajor Antal A Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, , Gothenburg, - - 2014
Bile acids may play a role in the pathogenesis of IBS. We investigated the potential effects of bile acids entering the colon and its role in the symptom pattern in IBS. We measured (75)Se-labelled homocholic acid-taurine ((75)SeHCAT) retention, and serum levels of 7α-hydroxy-4-cholesten-3-one (C4) and fibroblast growth factor (FGF) 19 ...
Campos-Juanatey Félix F Urology Department, Marqués de Valdecilla University Hospital, Santander, Cantabria, - - 2014
To assess the urodynamic patterns present in patients with adult normal pressure hydrocephalus (NPH) in our institution. Retrospectively conducted study on patients diagnosed with NPH by the Neurosurgery Department of our institution, without etiological treatment or urogynecological disorders, who underwent an urodynamic study (UDS) performed according to methods proposed by ...
Lindlau A A Clinical Neuroscience Unit, Department of Neurology, University Hospital Bonn, Bonn, - - 2014
Hippocampal atrophy is presumably one morphological sign of critical illness encephalopathy; however, predictors have not yet been determined. The data for this report derived from patients treated at the intensive care units (ICUs) of the University Hospital in Bonn in the years 2004-2006. These patients underwent structural magnetic resonance imaging ...
Barahona María-José MJ Department of Endocrinology, Hospital Universitari Mútua de Terrassa, Pl Dr Robert 5, 08221, Terrassa, Barcelona, Spain, - - 2014
Increased cardiovascular (CV) risk persists in Cushing's syndrome (CS), despite remission of hypercortisolism. The aim of this study was to evaluate prevalence of coronary artery disease in CS patients and its correlation with classical CV risk factors and inflammatory markers. Cardiac multidetector computed tomography (MDCT) was performed in 41 patients ...
Motovska Zuzana Z Third Medical Faculty of Charles Univ. and Univ. Hospital Kralovske Vinohrady, Srobarova 50, 100 34, Prague, Czech Republic, - - 2014
The purpose of the present study was to investigate the association between left ventricular systolic function and the response to clopidogrel. The efficacy of clopidogrel was measured by the vasodilator-stimulated phosphoprotein phosphorylation 20 ± 4 h after 600 mg of clopidogrel. High on-clopidogrel platelet reactivity (HCPR) was defined as a platelet reactivity index (PRI) ...
Khawaja Ali A aMedical College, The Aga Khan University bDepartment of Medicine, Section of Gastroenterology, The Aga Khan University Hospital, Karachi, - - 2014
Gastric variceal bleeding is one of the most feared complications of portal hypertension and hence merits investigation for its optimal therapy. We aimed to evaluate the efficacy and long-term outcome(s) of patients treated with a single session of histoacryl sclerotherapy for active gastric variceal bleeding. The medical records of patients ...
Lauret G J GJ Catharina Hospital, Department of Vascular Surgery, Eindhoven, The Netherlands; CAPHRI Research School, Maastricht University, Maastricht, The - - 2014
Reduced physical activity (PA) is associated with a higher mortality rate and more rapid functional decline in patients with intermittent claudication (IC). The newest generation of accelerometers can assess both direction and intensity of activities three-dimensionally and may also adequately calculate energy expenditure in daily life. The aim of this ...
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