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Palmieri Arianna A Department of Neurosciences, University of Padova, Padova, Italy Department of Philosophy, Sociology, Pedagogy and Applied Psychology (FISPPA), University of Padova, Padova, - - 2014
Cognitive impairment, mainly characterised by executive dysfunction, occurs in about half of cases in amyotrophic lateral sclerosis (ALS). There is evidence that gender influences some clinical features of the disease, but its influence on the cognitive spectrum is unknown. Our objective was to investigate the impact of gender on cognitive ...
Vayá Amparo A Hemorheology and Haemostasis Unit, Service of Clinical Pathology, La Fe University Hospital, Valencia, - - 2014
Increased red blood distribution width (RDW) in anemia is related to disturbances in the cellular surface/volume ratio, usually accompanied by morphological alterations, while it has been shown in inflammatory diseases that the activity of pro-inflammatory cytokines disturbing erythropoiesis increases RDW. Recently it has been reported that higher RDW is related ...
Howard Brian M BM Department of Neurological Surgery, Emory University School of Medicine, 1365-B Clifton Road, NE, Ste. 2200, Atlanta, GA 30322, USA. Electronic address: - - 2014
Intracranial hypotension typically presents following cerebrospinal fluid (CSF) leak, but can be induced by CSF diversion. Classically, patients present with positional headache, but less common symptoms include neck pain and cranial nerve palsies. To our knowledge, the neurosurgical literature contains six reports of patients with symptomatic cervical, epidural venous plexus ...
Desjardins Lucie L Inserm U1088, UFR de médecine et pharmacie, Jules Verne university of Picardy, 1, rue des Louvels, 80037 Amiens cedex 1, France; Clinical research centre, division of clinical pharmacology, Amiens university hospital, avenue Lænnec, 80054 Amiens cedex, France; The Jules Verne university of Picardy, 1, rue des Louvels, 80037 Amiens cedex 1, - - 2014
Sclerostin is a circulating inhibitor of the Wnt/β-catenin pathway and may have a role in chronic kidney disease (CKD)-mineral and bone disorder. Blood sclerostin levels are known to be elevated in patients undergoing maintenance dialysis. The aims of the present study were to evaluate sclerostin levels in patients at different ...
Jia Jue J The Affiliated Hospital of Jiangsu University, Zhenjiang 212001, - - 2014
Studies have examined the association between retinol-binding protein 4 (RBP4) and polycystic ovary syndrome (PCOS). However, the results have been inconsistent. To investigate the association between RBP4 and PCOS, we performed a meta-analysis. The Cochrane Library, MEDLINE, the ISI Web of Science, and EMBASE were searched to identify all of ...
Yu Hsin-Hui HH Department of Pediatrics, National Taiwan University Hospital, Taipei, - - 2014
The pathogenesis of juvenile dermatomyositis (JDM), the most common idiopathic inflammatory myopathy in children, is unclear. The identification of novel autoantibodies in JDM may have clinical implications. The aim of this study was to assess the presence of anti-p155/140, anti-p140 antibodies, and antiendothelial cells antibodies (AECA) in patients with JDM ...
Rey Johannes Wilhelm JW First Department of Internal Medicine, University Medical Center Mainz, Mainz, - - 2014
Background and Aims: Despite increasingly sensitive and accurate blood tests to detect liver disease, liver biopsy remains very useful in patients with atypical clinical features and abnormal liver tests of unknown etiology. The aim was to determine those elevated laboratory liver parameters that cause the clinician to order a biopsy, ...
Cancelliero-Gaiad Karina M KM Universidade Federal de São Carlos (UFSCar), São Carlos, SP, - - 2014
Diaphragmatic breathing (DB) is widely used in pulmonary rehabilitation (PR) of patients with chronic obstructive pulmonary disease (COPD), however it has been little studied in the scientific literature. The Pilates breathing (PB) method has also been used in the rehabilitation area and has been little studied in the scientific literature ...
Tsirakis George - - 2014
Objective Interleukin-22 (IL-22) is a cytokine participating in many aspects of inflammation. Multiple myeloma (MM) is a malignant disease of plasma cells with characteristic immune deregulation. We estimated serum levels of IL-22 in MM patients, both in activity and remission, in order to apprehend its possible participation in MM biology. ...
Oride A A Department of Obstetrics and Gynecology, Shimane University School of Medicine , Shimane Prefecture , - - 2014
This study aimed to determine the effectiveness of human menopausal gonadotropin (hMG) with and without clomiphene citrate (CC) for ovarian stimulation and oocyte retrieval in poor-responders. A total of 66 cycles in 13 patients met the inclusion criteria of 20 cycles of hMG stimulation and 46 cycles of CC + ...
Nassar Khaled K Department of Ophthalmology, University of Luebeck, Ratzeburger Allee 160, D-23538, Luebeck, Germany, - - 2014
This study evaluates the potential of serum pro-inflammatory cytokines as AMD biomarkers. Serum samples from 30 age-related macular degeneration (AMD) patients and 15 age-matched controls were examined for 16 inflammatory cytokines using multiplex ELISA. Patients were divided into three subgroups (improvement/no change/deterioration during anti-VEGF treatment) by OCT and funduscopy, and ...
Kulkantrakorn Kongkiat K Neurology Division, Department of Internal Medicine, Thammasat University, Rangsit Campus, Pathumthani, 12120, Thailand, - - 2014
High dose pyridoxine is neurotoxic. Previous case reports were sparse and little is known about the clinical and electrodiagnostic findings. Three patients with pyridoxine-induced sensory ataxic neuropathy were studied and a review of the involved literature was performed. Three patients, aged 80, 83 and 83 years old, presented with sensory ataxia ...
Yoshitomi Ryota R Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
The ankle-brachial blood pressure index (ABPI) has been recognized to have a predictive value for cardiovascular (CV) events and mortality in general or dialysis populations. However, the associations between ABPI and those outcomes have not been fully investigated in predialysis patients. The present study aimed to clarify the relationships between ...
Witkowski Grzegorz G 1st Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957, Warsaw, Poland, - - 2014
The DWI/FLAIR mismatch is a potential radiological marker for the timing of stroke onset. The aim of the study was to assess if the DWI/FLAIR mismatch can help to identify patients with both lacunar and nonlacunar acute ischemic stroke within 4.5 h of onset. A retrospective study was performed in which ...
Linquist Rebecca A RA Oculofacial Plastic and Orbital Surgery, Department of Ophthalmology, KU Eye, University of Kansas , Prairie Village, Kansas , USA - - 2014
Abstract Purpose: To examine the association of cytokines in the two clinical subtypes of ophthalmic Graves' disease by comparing cytokine expression in the fat and ethmoid tissue of type I and type II patients. Methods: Patients needing orbital decompression or eyelid surgery were identified and enrolled into a prospective study. ...
Lima Luciene Terezina de - - 2014
Background Genetic variations in membrane transporters may contribute to imatinib mesylate (IM) resistance in chronic myeloid leukemia (CML). Objective To investigate the relationship between SLCO1B3, SLCO1A2, and ABCA3 polymorphisms and IM response in CML patients. Methods Patients in chronic phase CML (N = 118) were studied. All patients were treated with a ...
Bartur Gadi G Reuth Rehabilitation Center, Tel Aviv, - - 2014
The objective of this study is to assess the autonomic nerve heart rate regulation system at rest and its immediate response to paced breathing among patients with complex regional pain syndrome (CRPS) as compared with age-matched healthy controls. Quasiexperimental. Outpatient clinic. Ten patients with CRPS and 10 age- and sex-matched ...
Mishra S M SM From the Departments of Clinical Neurosciences (S.M.M., T.T.S., A.T., M.A., E.Q., M.E., M.G., A.M.D., B.K.M.), Radiology (J.D., M.A., M.E., M.G., A.M.D., B.K.M.), and Community Health Sciences (T.T.S., B.K.M.), University of Calgary, Calgary, Alberta, Canada; Department of Neurology (S.I.S.), Dongsan Medical Center, Keimyung University, Daegu, South Korea; Faculty of Medicine (M.A.), King Abdulaziz University, Jeddah, Saudi Arabia; Department of Neurology (S.B.), University of Manitoba, Winnipeg, Manitoba, Canada; Department of Neurology (A.C.), Hospital Clinico Universitario, University of Valladolid, Valladolid, Spain; Seaman Family MR Center (M.A., E.Q., M.E., M.G., A.M.D., B.K.M.), Calgary, Alberta, Canada; and Hotchkiss Brain Institute (T.T.S., M.G., A.M.D., B.K.M.), Calgary, Alberta, - - 2014
An ability to predict early reperfusion with IV tPA in patients with acute ischemic stroke and intracranial clots can help clinicians decide if additional intra-arterial therapy is needed or not. We explored the association between novel clot characteristics on baseline CTA and early reperfusion with IV tPA in patients with ...
Al-Balbeesi Amal O AO Department of Dermatology (82), King Khalid University Hospital, King Saud University, Riyadh, Saudi - - 2014
Objective: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. Subjects and Method: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and ...
Qian G G Department of Dermatology & Rheumatology, The Second Affiliated Hospital of Kunming Medical University, Kunming, - - 2014
The current study was to investigate the features of hospitalized patients with systemic lupus erythematosus (SLE) at different altitudes. The correlation between SLE activity and altitudinal variations was also explored. Medical records of 1029 patients were retrospectively reviewed. Activity of SLE in each organ system was recorded using the Systemic ...
Djamshidian Atbin A Department of Molecular Neuroscience and Reta Lila Weston Institute for Neurological Studies, University of London, London, UK Department of Neurology, University Clinic Innsbruck, Tyrol, - - 2014
Background: It has been suggested that all patients with Parkinson's disease (PD) who undergo functional neurosurgery have difficulties in slowing down in high conflict tasks. However, it is unclear whether concomitant dopaminergic medication is responsible for this impairment. Objective: To assess perceptual decision making in PD patients with bilateral deep ...
Colucci R R Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, - - 2014
Autoantibodies against thyroid hormones (THAb) directed toward T3 (T3-Ab) and/or T4 (T4-Ab) are very rare in the general population and are increased in some non-thyroidal autoimmune diseases, where they seem to predict autoimmune thyroid disorders (ATD). So far, their presence in vitiligo patients has not been evaluated but might have ...
Chan Wah-Kheong WK Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of - - 2014
To study the natural history of NAFLD patients using paired liver biopsies and to determine factors associated with disease progression. Seventy-five NAFLD patients with liver biopsy in an earlier study were contacted. Patients who agreed for repeat liver biopsy were included. Factors associated with worsened NAFLD activity score (NAS) and ...
Tantawy Azza Abdel Gawad AA Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: - - 2014
High expression of growth differentiation factor-15 (GDF-15) contributes to pathological iron overload in thalassemia. Sickle cell syndromes are characterized by increased levels of erythropoiesis, although the primary defect involves the destruction of mature erythrocytes. To determine serum GDF-15 in 35 children and adolescents with sickle cell disease (SCD) compared to ...
Soofi Muhammad M Ohio State University College of - - 2014
With diminishing time afforded to electrocardiography in the medical curriculum, we have found Sibbitt's simple mnemonic (Diagonal Line Lead Rule, AHJ 1983) for a pattern recognition approach to 12 lead ECG interpretation to be much appreciated by students. However, it still lacks universal acceptance because its clinical utility has not ...
Zafón Carles C Department of Endocrinology, Hospital Vall d'Hebron, and Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain. Electronic address: - - 2014
Many reports have supported the relationship between high preoperative TSH levels and risk of thyroid cancer in nodular thyroid disease (NTD). We investigated whether TSH levels are related to the risk of differentiated thyroid carcinoma (DTC) in patients who have undergone total thyroidectomy for NTD. The relationship between TSH and ...
Tasaka Sadatomo S Division of Pulmonary Medicine, Keio University School of Medicine, Tokyo, Japan. Electronic address: - - 2014
Polymerase chain reaction (PCR) technique is being increasingly used for the microbiological diagnosis of Pneumocystis pneumonia (PCP). As PCR is highly sensitive, it can be positive even in a patient with Pneumocystis colonization. In this study, we evaluated whether the β-d-glucan assay could be used to differentiate between PCP and ...
Dollard James J Department of Cardiology, Cork University Hospital, Cork, Ireland; Alimentary Pharmabiotic Centre, University College Cork, Cork, - - 2014
Cardiac Syndrome X (CSX), the presence of angina pectoris despite normal epicardial coronary arteries seen on invasive angiography, is known to be associated with an elevation of several inflammatory biomarkers, suggesting a possible role for inflammation in its pathogenesis. We sought to establish if C-reactive protein (CRP) levels varied with ...
Bernardez-Pereira Sabrina - - 2014
Previous studies have shown the occurrence of actinin-3 deficiency in the presence of the R577X polymorphism in the ACTN3 gene. Our hypothesis is that this deficiency, by interfering with the function of skeletal muscle fiber, can result in a worse prognosis in patients with chronic heart failure. A prospective cohort ...
Al-Anqudi Samira M SM Department of Oral Health, Sultan Qaboos University Hospital, Muscat, - - 2014
The aim of this retrospective study was to investigate the prevalence and pattern of third molar impaction in patients between 19-26 years old attending Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. The study reviewed 1,000 orthopantomograms (OPGs) of patients attending the Oral Health Department of SQUH between October 2010 ...
Papa Linda L Department of Emergency Medicine, Orlando Regional Medical Center, 86 W. Underwood (S-200), Orlando, FL, 32806, USA, - - 2014
This study assessed whether early levels of biomarkers measured in CSF within 24-h of severe TBI would improve the clinical prediction of 6-months mortality. This prospective study conducted at two Level 1 Trauma Centers enrolled adults with severe TBI (GCS ≤8) requiring a ventriculostomy as well as control subjects. Ventricular CSF ...
Baxter Ma M Norfolk and Norwich University Hospital, Norwich, Norfolk, - - 2014
Abstract Introduction: Measurement of airways resistance is an alternative to spirometry to assess airflow obstruction. This can be measured by the interrupter technique (RInt) using a hand held device. We wished to know how RInt compared to forced expiratory volume in 1 second (FEV1) during a histamine challenge test. Methods: ...
Lorente Leonardo L Hospital Universitario de Canarias , Intensive Care , Ofra s/n , La Laguna, Tenerife, Spain , 38320 ; - - 2014
There is a hyperoxidative state in patients with trauma brain injury (TBI). Malondialdehyde (MDA) is an end-product formed during oxidative stress, concretely lipid peroxidation. In small studies (highest sample size 50 patients), higher levels of MDA have been found in non-surviving than surviving TBI patients. However, an association between serum ...
Li Juan J Rheumatology Department, Peking University First Hospital, Number 8, Xishiku Street West District, Beijing, 100034, - - 2014
This study was conducted to investigate the adverse reaction to cyclophosphamide (CYC) in Chinese patients with systemic autoimmune diseases. Patients with systemic autoimmune diseases who were exposed to CYC and followed up regularly for at least 2 years in Rheumatology Department during June 2003 to June 2013 were enrolled into this ...
Lützner Cornelia C Department of Orthopaedic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstr. 74, 01307, Dresden, - - 2014
Most patients expect an improvement of walking ability and an increase in activity levels after TKA. Unfortunately, few studies report qualitative and quantitative activity improvements after TKA. The aims of this study were (1) to evaluate quantity and quality of physical activity before and after TKA with an accelerometer, and ...
Chiba Kazuro K From the Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, - - 2014
The objective of this study was to evaluate picture of the major and minor duodenal papillae in patients with autoimmune pancreatitis (AIP). Endoscopic features of the major and minor papillae were examined in 59 and 13 patients with AIP. After steroid therapy, changes of the major and minor papillae were ...
Wu Congye C From the Department of SICU, Research Institute of General Surgery, Jinling Hospital, Medicine School of Nanjing University, Nanjing, Jiangsu, - - 2014
The aim of this study was to investigate the risk factors for acute kidney injury (AKI) in patients with acute pancreatitis (AP). Patients with AP were retrospectively divided into AKI group and non-AKI group. To investigate the risk factors for AKI, logistic regression analysis was performed with demography, etiologies, and ...
Munguía-Izquierdo Diego D 1Dept. of Sports and Informatics, Section of Physical Education and Sports, Faculty of Sports, Universidad Pablo de Olavide, Sevilla, Spain; 2European University and Research Institute 'i+12', Madrid, - - 2014
This study sought to determine whether health-related quality of life (HRQoL) could be related to cardiorespiratory fitness (CRF) and/or physical activity (PA) in patients with McArdle disease and to compare the CRF and HRQoL data obtained with normative data for age- and sex-matched healthy subjects. Eighty-one adult McArdle patients underwent ...
Mizushima Ichiro - - 2014
Immunoglobulin G4 (IgG4)-related aortitis/periaortitis and periarteritis are vascular manifestations of IgG4-related disease. In this disease, the affected aneurysmal lesion has been suspected to be at risk of rupture. This study aimed to clarify the clinical course after corticosteroid therapy in IgG4-related aortitis/periaortitis and periarteritis. We retrospectively evaluated clinical features including ...
Ali Masood M Department of Respiratory Medicine, Southend University Hospital NHS Foundation Trust, - - 2014
Reduced atmospheric pressure during air travel can cause significant hypoxaemia in some patients with respiratory disease. Our aims were to investigate the degree of hypoxaemia in patients with obesity hypoventilation syndrome (OHS) during hypoxic challenge test (HCT), and to identify any predictors of a positive HCT. Thirteen patients underwent assessment, ...
Kallmünzer Bernd B From the Department of Neurology, Universitätsklinikum Erlangen, Germany. - - 2014
To investigate feasibility and diagnostic accuracy of measurement of the peripheral pulse (MPP) at the radial artery as a simple, noninvasive screening tool for paroxysmal atrial fibrillation (pAF) in patients after acute ischemic stroke.METHODS: Two hundred fifty-six patients with acute ischemic stroke and the patients' relatives at a tertiary stroke ...
Itabashi Ryo R Department of Stroke Neurology, Kohnan Hospital, Sendai, - - 2014
Background: The incidence of heart disease or deep vein thrombosis (DVT) reportedly increased after the Great East Japan Earthquake. We hypothesized that the incidence of cardioembolic stroke (CES) including paradoxical brain embolism (PBE) among patients with acute stroke would increase after the earthquake due to cessation of antithrombotic therapy or ...
Asazawa Hitomi - - 2014
Abstract Background: Fucosylation is one of the most important glycosylation events involved in cancer and inflammation. We previously developed a lectin antibody ELISA kit to measure fucosylated haptoglobin (Fuc-Hpt), which we identified as a novel cancer biomarker. In this study, we investigated Fuc-Hpt as a biomarker in chronic liver diseases, ...
Solís-Vivanco Rodolfo R Neuropsychology Department, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez (INNNMVS), Insurgentes Sur 3877, Col. La Fama, Tlalpan, Mexico City C.P. 14269, Mexico. Electronic address: - - 2014
Mismatch Negativity (MMN), an electrophysiological component that represents sensory memory processing, has been proposed as a potential vulnerability marker for psychosis. Some studies have reported a more evident MMN amplitude reduction in the left cortical regions in patients with schizophrenia. Little is known about this asymmetric pattern in patients in ...
Zincir Serkan S Golcük Military Hospital, Department of Psychiatry, Golcük, 41650 Kocaeli, Turkey. Electronic address: - - 2014
Nitric oxide (NO) is thought to be involved in the pathogenesis of schizophrenia as well as many neuropsychiatric disease. Asymmetric dimethylarginine (ADMA) reduces the level of NO by inhibiting nitric oxide synthase (NOS) enzyme. In this study it is aimed to be investigated ADMA in patients with first-episode schizophrenia. In ...
Aiyer Amiethab A Department of Orthopaedic Surgery, Penn State University/Milton S Hershey Medical Center, 30 Hope Dr, Hershey, PA, 17033, USA, - - 2014
Lyme arthritis can be readily treated with use of oral antibiotics without any need for surgery. In Lyme-endemic areas, differentiating between Lyme arthritis and septic arthritis can be difficult. Laboratory testing for Lyme disease often results in a delay in diagnosis because many labs batch-test Lyme specimens only two times ...
Zenda Takahiro T Department of Internal Medicine, Hokuriku Central Hospital of Japan Mutual Aid Association of Public School Teachers , Toyama , - - 2014
Abstract Objective. The pathogenetic relationship underlying the high prevalence of gastroesophageal reflux disease (GERD) in patients with obstructive sleep apnea (OSA) remains unclear. In addition, GERD has not been adequately assessed by endoscopy in patients with OSA. The purpose of this study was to use endoscopy to investigate potential interactions ...
Hadiji N N Centre Bouffard-vercelli-Laboratoire de neuro-urologie et de sexologie, Cerbère, - - 2014
Objectives:To evaluate the efficacy of anticholinergic agents in the treatment of neurogenic overactive bladder (NOAB) and neurogenic detrusor overactivity (NDO) in spinal cord injury (SCI) patients on clean intermittent catheterisation (CIC).Methods:Chronic suprasacral SCI patients on CIC presenting with at least one urinary leakage a day were included. Urodynamics and voiding ...
Fritz S S Departments of General, Visceral and Transplantation - - 2014
Autoimmune pancreatitis (AIP) is characterized by diffuse or focal swelling of the pancreas. AIP has been divided into types 1 and 2. The aim of the study was to evaluate and compare the clinicopathological characteristics, therapy and outcome of patients with AIP. The medical records of patients diagnosed with AIP ...
Yamamoto Yoshiaki Y Department of Clinical Research, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886, Urushiyama, Shizuoka, 420-8688, Japan, - - 2014
The aim of this study was to evaluate the effect of cytochrome P450 (CYP) inducers/inhibitors on the pharmacokinetics of clobazam (CLB) in patients receiving antiepileptic polypharmacy. A total of 2,504 samples obtained from 1,280 patients for routine therapeutic drug monitoring were retrospectively reviewed. These samples were grouped according to the ...
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