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Results 351 - 400 of 14665
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Ikeura Tsukasa T From the *The Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan; †Department of Pathology, Odense University Hospital, Odense, Denmark; Departments of ‡Pathology, §Radiology, and ∥Medicine, Pancreas Center, University of Verona, Verona, Italy; and ¶Department of Pathology, University of Kiel, Kiel, - - 2014
The objective of this study was to compare the preoperative diagnosis by International Consensus Diagnostic Criteria (ICDC) with histological diagnosis in patients with focal autoimmune pancreatitis (AIP) who underwent surgery. Thirty patients (type 1 AIP in 23 and type 2 AIP in 7) with a diagnosis of AIP based on ...
Chauhan Monika M Department of Pediatrics, Division of Critical Care, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan. Electronic address: - - 2014
Temporary epicardial pacing wires are commonly placed in patients undergoing surgery for congenital heart disease. Though often helpful, these wires are not without risk. We aimed to identify characteristics that would obviate placement of temporary epicardial pacing wires in this patient population. A prospective observational study was performed on patients ...
Depew Zachary S ZS Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, - - 2014
Nonspecific pleuritis (NSP) is a frequent diagnosis after parietal pleural biopsy, but the clinical significance of this finding and need for further follow-up have not been firmly established. Previous reports suggest that 5% to 25% of patients with NSP are subsequently diagnosed with pleural malignancy. Our pathology database was queried ...
Koutsis Georgios G Neurogenetics Unit, 1st Department of Neurology, University of Athens Medical School, Eginition Hospital, Athens, Greece. Electronic address: - - 2014
To address diagnostic and prognostic issues in patients with late-onset Huntington's disease (HD). We analyzed a cohort of 41 late-onset (≥60 years) HD patients and compared them to 39 late-onset patients referred for HD testing that were negative for the HD-expansion and to 290 usual-onset (20-59 years) HD patients. Disease ...
Araten David J - - 2014
PNH is associated with abdominal vein thrombosis, which can cause splenomegaly and hypersplenism. The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding risk. Splenectomy could alleviate thrombocytopenia and reduce portal pressure, but it can cause post-operative thromboses and opportunistic ...
Baum S S Department of Dermatology, Tel Hashomer, and The Sackler School of Medicine, Tel Aviv - - 2014
Onchocerciasis is an infectious disease caused by the filaria Onchocerca volvulus. Very little is known regarding onchocerciasis imported from endemic to non-endemic areas. To evaluate pruritic dermatitis simulating atopic dermatitis in Ethiopian immigrants in Israel. A retrospective study on 27 Ethiopian immigrants to Israel was conducted. Demographics and clinical and ...
Usui Shingo S Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, - - 2014
We have reported that second-generation colon capsule endoscopy (CCE-2) might be feasible for assessing the severity of mucosal inflammation in ulcerative colitis (UC). However, because of the low rate (69%) of complete evaluation of the colon and owing to inadequate cleansing. We believe that the method of bowel preparation could ...
Chiew A L AL Department of Emergency Medicine, Clinical and Experimental Toxicology Unit, Prince of Wales Hospital , Randwick, NSW , - - 2014
Context. Dabigatran etexilate is one of the newer oral anticoagulants and a direct thrombin inhibitor. Concerns regarding dabigatran's use include its lack of validated laboratory markers for measuring its anticoagulation effect, the impact of renal impairment on its clearance, and the lack of effective strategies for reversal of anticoagulation. Hemodialysis ...
Metternich B B Epilepsy Center, University Medical Center Freiburg, Breisacher Str. 64, 79106, Freiburg, Germany, - - 2014
Testing of verbal fluency is currently part of standard presurgical neuropsychological assessment for patients with focal epilepsy. However, to date no systematic review has been conducted on semantic (SVF) and phonemic verbal fluency (PVF) in this patient group. The present review compares verbal fluency between healthy control subjects and subgroups ...
Buiten M S MS Department of Cardiology, Leiden University Medical Center (LUMC), , Leiden, The - - 2014
Atrial fibrillation (AF) is common in dialysis patients and is associated with increased morbidity and mortality. The pathophysiology may be related to common risk factors for both AF and renal disease or to dialysis-specific factors. The purpose of this study was to determine whether and how AF onset relates to ...
Cavalier Etienne - - 2014
Abstract Background: Standardization of parathyroid hormone (PTH) assays is a major issue, especially in hemodialyzed (HD) patients. Two automated third generation PTH assays (Roche Elecsys and DiaSorin Liaison) are now available. These assays are specific for the (1-84) PTH and do not cross-react with the (7-84) fragment, contrary to second ...
Abe Ayumi A Department of Otolaryngology, Sapporo Medical University School of Medicine , Sapporo , - - 2014
Objectives. Mikulicz's disease (MD) is an immunoglobulin (Ig) G4-related disease with systemic symptoms. Submandibular gland (SMG) biopsy is recommended for patients with possible IgG4-related MD for accurate differential diagnosis; however, it is difficult for certain patients to undergo this procedure. In contrast, labial salivary gland (LSG) biopsy is more convenient. ...
Kimura Koichi K Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, - - 2014
The clinical presentations of gastrointestinal bleeding (GIB) occurring after living donor liver transplantation (LDLT) have not been fully described. We performed a retrospective analysis of 297 LDLT cases. Nineteen patients (6.4%) experienced GIB after LDLT. The etiology of GIB included bleeding at the jejuno-jejunostomy following hepatico-jejunostomy (n = 13), peptic ...
Bhidayasiri Roongroj R Chulalongkorn Center of Excellence on Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Bangkok, 10330, Thailand, - - 2014
While nocturnal disturbances of Parkinson's disease (PD) are increasingly recognized as being part of a continuum that includes daytime manifestations, there is still little analysis in the medical literature that assesses these complex phenomena in patients with atypical (AP) and vascular parkinsonisms (VP). The objective of our study was to ...
Tekce Buket Kin BK Department of Medical Biochemistry, Faculty of Medicine, Abant Izzet Baysal University, Bolu, - - 2014
It is not possible to diagnose acute kidney injury (AKI) in early stages with traditional biomarkers. Kidney injury molecule-1 (KIM-1) is a novel biomarker promising the diagnosis of AKI in early stages. We studied whether urinary and serum KIM-1 (KIM-1U and KIM-1S) concentrations were useful in predicting cisplatin-induced AKI in ...
Koca Irfan I Department of Physical Therapy and Rehabilitation, Gaziantep University, Faculty of Medicine , Gaziantep , - - 2014
Objective. To evaluate total antioxidant capacity (TAC) and total oxidative stress (TOS) values in patients with myofascial pain syndrome (MPS). Method. The study comprised 38 patients diagnosed with MPS and 30 healthy volunteers. The age, body mass index (BMI) and pain scores (evaluation by visual analogue scales) of all the ...
Han Bing B Department of Vascular Surgery, The Second Hospital of Baoding City, Baoding 071051, Hebei Province, - - 2014
To investigate the prevention of pulmonary embolism (PE) by the implantation of inferior vena cava filters (IVCFs). Data of 1058 patients treated for lower extremity deep vein thrombosis (DVT) between January 2005 and January 2012 were analyzed retrospectively and divided into those with and without PE. Of the 1058 patients, ...
Sipol Alexandra A - - 2014
Objectives Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder characterized by partial or absolute deficiency of glycophosphatidyl-inositol (GPI) anchor-linked surface proteins on blood cells. A lack of precise diagnostic standards for flow cytometry has hampered useful comparisons of data between laboratories. We report data from the first ...
Sunnetcioglu Mahmut - - 2014
Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase, is considered to be associated with endothelial dysfunction. High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis. Cutaneous anthrax (CA) is a serious ...
Antunes Henedina H Gastroenterology, Hepatology and Nutrition Unit, Pediatrics Department, Hospital de Braga , Braga , - - 2014
Abstract Introduction. The incidence of acute pancreatitis (AP) in children has increased significantly in the past two decades. Objective. All cases of AP, acute recurrent pancreatitis (ARP), and chronic pancreatitis examined between May 2002 and May 2012 at Hospital de Braga, Portugal, were reviewed. Material and methods. Patients were identified ...
Fang Tuan-Jen TJ Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC; School of Medicine, Chang Gung University, Taoyuan, Taiwan, - - 2014
Objectives: To assess the possible predictive factors for permanent laryngoplasty (PL) in patients with acute unilateral vocal fold paralysis (UVFP), and to assess the effects of early vocal cord hyaluronic acid injection. Study design: Prospective cohort study. Methods: Patients diagnosed with UVFP within the previous 6 months were enrolled. Initial ...
Rino Yasushi Y Department of Surgery, Yokohama City University Graduate School of Medicine, 3-9, Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan, - - 2014
To clarify factors related to vitamin E malabsorption after gastric surgery, we evaluated serum vitamin E levels in patients who had undergone gastrectomy for gastric cancer. We studied 39 patients (26 men, 13 women; mean age, 61.7 years) who underwent gastrectomy for early gastric cancer. Surgical procedures included 24 subtotal gastrectomies ...
Logallo Nicola N Center for Neurovascular Diseases, Haukeland University Hospital, Bergen, Norway. Electronic address: - - 2014
There is no data about prevalence of intracranial stenosis (IS) in Northern Europe. This study aimed to investigate the prevalence of symptomatic and asymptomatic IS in a Norwegian, community-based ischemic stroke population. In a prospective study, all ischemic stroke or transient ischemic attack (TIA) patients were screened for IS by ...
Bangalore Sripal S New York University Medical Center, New York, NY. Electronic address: - - 2014
Patients with stroke or transient ischemic attack are at increased risk of recurrent stroke. Transient ischemic attack is a harbinger for stroke merely hours to days after the initial transient ischemic attack. There is thus a narrow window of opportunity to initiate evidence-based therapies for secondary prevention of stroke. Our ...
Joshi Dolly D Department of Cytogenetics, National Institute of Immunohaematology, 13th Floor, New Multistoried Building, KEM Hospital Campus, Parel, Mumbai 400012, - - 2014
Chronic myeloid leukemia (CML) occurs due to t(9,22) (q34;q11) and molecularly BCR/ABL gene fusion. About 15-18% Philadelphia positive CML patients have gene deletions around the translocation breakpoints on 9q34.1. The microRNAs (miRNAs), namely miR-219-2 and miR-199b, centromeric to the ABL1 gene are frequently lost in CML patients. We have designed ...
Katzka David A DA Divisions of Gastroenterology and Hepatology and Pathology, Mayo Clinic, Rochester. Electronic address: - - 2014
& Aims: The allergic response associated with eosinophilic esophagitis (EoE) occurs when food antigens permeate tight junction-mediated epithelial dilated intercellular spaces. We assessed whether levels of tight junction proteins correlate with dilation of intercellular spaces (spongiosis) and the effects of topical steroids on these parameters. We assessed esophageal biopsy samples ...
Castells Antoni A Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain. Electronic address: - - 2014
& Aims: We compared the ability of biennial fecal immunochemical testing (FIT) and 1-time sigmoidoscopy to detect colon side-specific advanced neoplasms in a population-based, multicenter, nation-wide, randomized controlled trial. We identified asymptomatic men and women, 50-69 years old, through community health registries, and randomly assigned them to groups that received ...
Moon Jun-Gyu JG Department of Orthopaedic Surgery, Korea University Guro Hospital, Seoul, Korea. Electronic address: - - 2014
The purpose of this study was to examine clinical findings of septic arthritis of the elbow joint in a series of immunocompetent patients and to evaluate the outcomes after arthroscopic treatment. Between October 2006 and January 2012, 11 patients with septic arthritis of the elbow underwent arthroscopic surgery. History, laboratory ...
Díez Juan J JJ Servicio de Endocrinología, Hospital Ramón y Cajal, Madrid, España; Universidad de Alcalá de Henares, Alcalá de Henares, Madrid, España. Electronic address: - - 2014
To assess whether subclinical hypothyroidism is associated to elevations in serum cholesterol and triglyceride levels in patients with type 2 diabetes. From a total population of 1,112 patients with type 2 diabetes screened for thyroid dysfunction (thyrotropin measurement), a group of 325 patients with normal thyroid function and another group ...
Michou Emilia E Centre for Gastrointestinal Sciences - Institute of Inflammation and Repair, University of Manchester (part of the Manchester Academic Health Sciences Centre (MAHSC)), Salford Royal Hospital, M6 8HD, - - 2014
& Aims: Dysphagia in patients with Parkinson's disease, persisting despite dopaminergic treatment, affects intake of nutrients and medication, and reduces quality-of-life (QOL). We investigated the neurophysiologic mechanisms that contribute to dysphagia in these patients, on and off levodopa, using transcranial magnetic stimulation. We studied 26 patients with Parkinson's disease (65±9 ...
Fernandez Vanessa V Cardiology Department, CHU Dijon, Dijon, - - 2014
Background: Since atrial fibrillation (AF) may be undiagnosed when asymptomatic and paroxysmal, we aimed to investigate the incidence and determinants of silent AF in patients with acute ischemic stroke or transient ischemic attack (TIA). Methods: Consecutive patients admitted to the Stroke Unit of the University Hospital of Dijon, France, for ...
Caumes Roseline R APHP, Hôpital Robert Debré, Service de Neurologie Pédiatrique, 75019 Paris, - - 2014
Mutation of the X-linked methyl CpG binding protein 2 (MECP2) has been first identified as the cause of Rett syndrome. More recently, MECP2 gene duplication syndrome has been identified in males. The MECP2 duplication syndrome is characterized by severe mental retardation, infantile hypotonia, progressive spasticity and recurrent infections. Epileptic seizures ...
Cetiner Mehmet Ali MA Cardiology Department, Karadeniz Eregli State Hospital, Zonguldak, - - 2014
In this study, we examined the role of isovolumic acceleration (IVA) measured with right ventricle (RV) tissue Doppler imaging (TDI) to predict the presence of acute pulmonary embolism (APE) in hemodynamically stable patients with clinical suspicion of APE. This study included 25 hemodynamically stable (systolic blood pressure >90 mmHg) patients diagnosed with ...
Gerdes Sascha S Psoriasis-Center at the Department of Dermatology, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, - - 2014
Psoriasis is a systemic inflammatory disease of the skin with associated comorbidity. Severe forms of psoriasis are associated with increased mortality which might be due to cardiovascular comorbidity. In this study we investigated in 79 patients with psoriasis compared to 80 healthy volunteers different biomarkers that play a role in ...
Meloni Antonella A CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy; Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, - - 2014
Chronically transfused sickle cell disease (SCD) patients have lower risk of myocardial iron overload (MIO) than comparably transfused thalassemia major patients. However, cardioprotection is incomplete. We present the clinical characteristics of 6 patients who have prospectively developed MIO, to identify potential risk factors for cardiac iron accumulation. From 2002 to ...
Moos Shira I SI Department of Radiology, G1-215, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, - - 2014
To assess which risk factors can be used to reduce superfluous estimated glomerular filtration rate (eGFR) measurements before intravenous contrast medium administration. In consecutive patients, all decreased eGFR risk factors were assessed: diabetes mellitus (DM), history of urologic/nephrologic disease (HUND), nephrotoxic medication, cardiovascular disease, hypertension, age > 60 years, anaemia, malignancy and multiple ...
Mahfouz Ragab A RA Cardiology Department, Zagazig University Hospitals, Zagazig, - - 2014
We sought to study diastolic function in patients with low-flow/low-gradient aortic stenosis (LF/LGAS) and to clarify the relationship between contractile reserve on dobutamine stress echocardiography (DSE) and the restrictive filling pattern on echocardiography in patients with LF/LGAS. Thirty patients with LF/LG severe AS were divided into 2 groups. Group I ...
Bauer Angela A Department of Pediatrics, University Medical Center Hamburg, Hamburg, - - 2014
The aim of this study was to analyze the neurological involvement and outcome in pediatric patients with hemolytic uremic syndrome (HUS) during the 2011 epidemic caused by Escherichia coli O104:H4. Clinical data and data from magnetic resonance imaging (MRI) scans and electroencephalography (EEG) during the acute phase of the disease ...
Daviaud Fabrice F Medical Intensive Care Unit, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris, 27 rue du Faubourg Saint Jacques, 75014, Paris, France, - - 2014
The influence of blood glucose (BG) level during the post-resuscitation period after out-of-hospital cardiac arrest (OHCA) is still debated. To evaluate the relationship between blood glucose level and outcome, we included the median glycemia and its maximal amplitude over the first 48 h following ICU admission in an analysis of outcome ...
Bongartz Tim T Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, - - 2014
To assess the accuracy of dual-energy CT (DECT) for diagnosing gout, and to explore whether it can have any impact on clinical decision making beyond the established diagnostic approach using polarising microscopy of synovial fluid (diagnostic yield). Diagnostic single-centre study of 40 patients with active gout, and 41 individuals with ...
John Katja K University Leipzig, Department of Cardiac Surgery, Heart Center, Leipzig, - - 2014
Background: In the last years many studies have been designed to predict risk of acute rejection and to adapt the immunosuppressive therapy. The importance of dendritic cells (DCs) in the immune response, especially their role in tolerance is known. Thus, we investigated the influence of tacrolimus (TAC)-based and of cyclosporine ...
Umarova Roza M RM Department of Neurology, University Medical Centre Freiburg, Freiburg, Germany; Freiburg Brain Imaging, University Medical Centre Freiburg, Freiburg, Germany; BrainLinks-BrainTools Cluster of Excellence, University of, Freiburg, - - 2014
Visual neglect results from dysfunction within the spatial attention network. The structural connectivity in undamaged brain tissue in neglect has barely been investigated until now. In the present study, we explored the microstructural white matter characteristics of the contralesional hemisphere in relation to neglect severity and recovery in acute stroke ...
Chen L L Department of Colorectal Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Zhejiang, - - 2014
The neutrophil-to-lymphocyte ratio (NLR) is a novel inflammation index that has been shown to independently predict poor clinical outcomes. We aimed to evaluate the role of NLR in the prediction of 3-month mortality in patients with acute-on-chronic liver failure (AoCLF). One hundred and twenty-seven patients, including 46 patients with chronic ...
Lee Jung Hyun JH Department of Pediatrics, the Catholic University of Korea, St. Vincent's Hospital, 93-6, Ji-dong, Paldal-gu, Suwon-si, Gyeonggi-do, Republic of - - 2014
Graves' ophthalmopathy (GO) occurs commonly in children with Graves' disease (GD). However, there are limited studies on the clinical manifestations and thyroid autoantibodies in pediatric GO. The aim of this study was to investigate the prevalence and risk factors of GO in childhood GD. Clinical and biochemical data from children ...
Ozturk Cengiz C 1Department of Cardiology, Gulhane Medical Academy, Ankara, - - 2014
Behçet disease (BD) is associated with endothelial dysfunction and chronic inflammation. The neutrophil-lymphocyte (N/L) ratio and carotid intima-media thickness (cIMT) are markers of inflammation and vascular risk, respectively. We assessed the relationship between cIMT values and N/L ratio in BD (65 patients and 62 control participants). There were statistically significant ...
Maffei Francesca F Department for Life Quality Studies, University of Bologna, Corso d'Augusto 237, 47921 Rimini, - - 2014
The early detection of colorectal cancer (CRC) can significantly improve the prognosis of affected patients. The loss of genomic stability and the resulting gene alteration play an important role in the molecular pathological steps that occur early in tumorigenesis of CRC. Thus, the identification of non-invasive biomarkers, whose function may ...
Hongjun K K Department of Critical Care Medicine, Chinese PLA General Hospital, Beijing, - - 2014
The objective of the present study was to evaluate different stage fluid and standard drug treatment strategies in 47 heatstroke patients. 47 adults with Heatstroke received fluid resuscitation treatment guided by transpulmonary thermodilution (PiCCO) in our intensive care unit. Systemic hemodynamics, microvascular indices and measures of acidosis, renal function, and ...
Cismaru Gabriel G Department of Cardiology-Rehabilitation Hospital, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, - - 2014
The most commonly used drug for the facilitation of supraventricular tachycardia (SVT) induction in the electrophysiological (EP) laboratory is isoprenaline. Despite isoprenaline's apparent indispensability, availability has been problematic in some European countries. Alternative sympatomimethic drugs such as adrenaline have therefore been tried. However, no studies have determined the sensitivity and ...
Roberto Maggi M Dipartimento di Cardiologia, Ospedali del Tigullio, Centro Aritmologico, Lavagna, - - 2014
Non-syncopal transient loss of consciousness (T-LOC) encompasses disorders that sometimes resemble syncope, and the differential diagnosis with true syncope may be challenging. The implantable loop recorder (ILR) is potentially useful, but has never been systematically assessed. The aim of the study is to evaluate the diagnostic value of ILR in ...
Manganiello Sabrina S Cardiology Division, Department of Medical Sciences, University of Turin, Turin, - - 2014
Atrial fibrillation (AF) relapses, following transcatheter AF ablation, are frequently reported based on patients' symptoms, scheduled electrocardiograms (ECGs), or 24-hour Holter recordings. The aim of this study is to determine the incidence of asymptomatic and symptomatic AF recurrences, using continuous subcutaneous ECG monitoring, in the long-term follow-up of patients with ...
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