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Sternick Eduardo Back EB Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, Brazil; Instituto de Pós-Graduação, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, - - 2014
A 28-year-old male patient with a 3-year history of recurrent tachycardia was referred for electrophysiologic evaluation and catheter ablation. The patient had no other co-morbidities. Propafenone was discontinued 7 days before admission. This article is protected by copyright. All rights reserved.
Kaski D D Department of Neuro-otology, Imperial College London, Charing Cross Hospital, London W6 8RF, United Kingdom. Electronic address: - - 2014
Gait disturbance in patients with Parkinson's disease remains a therapeutic challenge, given its poor response to levodopa. Dance therapy is of recognised benefit in these patients, particularly partnered dance forms such as the tango. In parallel, non-invasive brain stimulation has begun to show promise for the rehabilitation of patients with ...
Deguchi Ichiro I Department of Neurology, Saitama Medical University International Medical Center, Saitama, Japan. Electronic address: - - 2014
The presence or absence of the penumbra area is important when performing reperfusion therapy in patients with acute ischemic stroke. As a predictor of this penumbra area, magnetic resonance angiography (MRA)-diffusion-weighted imaging (DWI) mismatch is attracting attention. The usefulness of MRA-DWI mismatch (MDM) using the DWI-Alberta Stroke Program Early Computed ...
Di Stefano Rossella R aDepartment of Surgical, Medical and Molecular Pathology and Critic Area bDepartment of Clinical and Experimental Medicine, Psychiatry Sector, University of Pisa, Pisa cUnit of Cardiology, Ospedale S. Andrea, La Spezia dCardio-Respiratory Department, Ospedale Campo di Marte, Lucca eUnit of Cardiology, USL5 Sarzana (SP), Italy *Rossella Di Stefano and Francesca Felice contributed equally to the writing of this - - 2014
Depression has been identified as a risk factor for an adverse prognosis and reduced survival in patients with acute coronary syndrome (ACS). The number of endothelial progenitor cells (EPCs) is an independent predictor of clinical outcomes in patients with ACS. The aim of this study was to evaluate the impact ...
Yang Shuangshuang S Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. - - 2014
Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) is considered as an effective predictor for patients with heart failure (HF), while a strong body of evidence has found its utility in inflammatory diseases. It is difficult to differentiate HF and HF coexisting with other inflammations by measuring NT-proBNP. The aim of this ...
Jacob Ron R Department of Pediatrics B, Meyer Children's Hospital of Haifa, Rambam Medical Center, Faculty of Medicine, Technion, Haifa, - - 2014
Respiratory disease is a common reason for hospitalization and mortality in persons with severe intellectual and developmental disability. Capnography is the measurement and numerical display of end-tidal carbon dioxide (EtCO2). This was a prospective, case controlled, cross sectional study to assess differences of baseline EtCO2 values between neurologically impaired patients ...
Celikbilek Mehmet M Department of Gastroenterology, Bozok University Medical School, Yozgat, - - 2014
Blood neutrophil-to-lymphocyte (N/L) ratio is an indicator of the overall inflammatory status of the body, and an alteration in N/L ratio may be found in patients with familial Mediterranean fever (FMF). The aim of this study was to investigate the interrelationship between N/L ratio and FMF. One hundred and fifteen ...
Cushen Samantha J SJ *Department of Food & Nutritional Sciences ∥School of Mathematical Science, University College Cork †Department of Medical Oncology, Mercy & Cork University Hospitals §Department of Radiology, Mercy University Hospital, Cork ‡Department Medical Oncology, Adelaide & Meath Hospital incorporating National Children's Hospital, Tallaght, - - 2014
Sunitinib is a standard first-line option for metastatic renal cell carcinoma (mRCC). Body composition is a prognostic factor in cancer patients and patients with loss of skeletal muscle mass and fat-free mass (FFM) are prone to dose-limiting toxicity (DLT) during targeted drug therapy. We investigated whether body composition by computed ...
Leyhe Thomas T Center of Old Age Psychiatry, Psychiatric University Hospital, Basel, Switzerland. Electronic address: - - 2014
Hashimoto's thyroiditis (HT) is the most frequent cause of hypothyroidism in areas with sufficient iodine intake. While the impact of thyroid function on mood and cognition is well known, only in the recent years, an increasing number of studies report on the association of HT with cognitive and affective disturbances ...
Werner Christian C Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Homburg/Saar, - - 2014
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL-cholesterol receptor homeostasis and emerges as a therapeutic target in the prevention of cardiovascular (CV) disease. This prospective cohort study analyzes risk prediction with PCSK9 serum concentrations in patients with stable coronary artery disease (CAD) on statin treatment. Fasting PCSK9 ...
Masuda Hiroshi H Department of Cardiovascular Medicine, Juntendo University, School of Medicine, Tokyo, - - 2014
Rheumatoid arthritis (RA) increases the mortality and morbidity of cardiovascular disease (CVD). However, the relationship between RA and the risk of CVD in the Japanese population remains unclear. This study comprised 571 RA patients who were admitted to Juntendo University Hospital from January 1990 to December 2000. Cardiovascular events (CVEs) ...
Carvalho Ana Teresa P AT Ana Teresa P Carvalho, Barbara C Esberard, Renata S B Fróes, Ana B Grinman, Disciplina de Gastroenterologia e Endoscopia Digestiva, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, - - 2014
To analyze the prevalence of thiopurine-methyltransferase (TPMT) genotypes and their association with drug toxicity in inflammatory bowel disease (IBD) patients from southeastern Brazil. A total of 219 consecutive patients with IBD, of which 146 had Crohn's disease and 73 had ulcerative colitis, regularly seen at the outpatient unit of the ...
Watabe Hiroaki H Department of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, - - 2014
The association between contrast-induced acute kidney injury (CI-AKI) and chronic kidney disease (CKD) in patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI) has not been fully reported. We evaluated the association of CI-AKI on cardiovascular events in ACS patients with CKD. A total of 1059 ACS ...
Izuhara Y Y Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, - - 2014
In steroid-naive patients with asthma, several gene variants are associated with a short-term response to inhaled corticosteroid (ICS) treatment; this has mostly been observed in Caucasians. However, not many studies have been conducted for other ethnicities. Here, we aimed to determine the relationship between the annual decline in forced expiratory ...
Khow Kareeann S F KS Department of General Medicine, Flinders Medical Centre , Adelaide , Australia - - 2014
Abstract Elevated creatine kinase (hyper-CKemia) has been observed in small number of patients with hyponatremia. This study evaluated the features and outcomes of patients admitted with hyponatremia complicated by hyper-CKemia. Patients admitted with hyponatremia and concurrently found to have elevated creatine kinase (CK) of above 375 IU/L (male) or 225 IU/L (female), ...
Firinci Fatih F Department of Pediatrics, Dokuz Eylul University School of Medicine , İzmir , Turkey - - 2014
Abstract Aim: To assess the relationship between mesangial hypercellularity in various childhood nephropathies and clinical and laboratory parameters. Methods and patients: The reports of the renal biopsies were evaluated retrospectively. The patients with diagnosis of IgA nephropathy (isolated and Henoch-Schönlein nephritis), IgM nephropathy, or isolated mesangial proliferative glomerulonephritis were included. ...
Rupa-Matysek Joanna J Department of Haematology, Poznan University of Medical Sciences, Szamarzewskiego 84, 60-569, Poznan, Poland, - - 2014
Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked venous thromboembolism. The aim of our study was to evaluate MPV in patients with confirmed antiphospholipid antibody syndrome (APS) and to identify the correlation between the value of MPV and the ...
Plešivčnik Novljan Martina M Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, - - 2014
The objective of the study is to compare the longitudinal performance of different classification criteria for primary Sjögren's syndrome (SS) in a cohort of patients previously diagnosed with primary SS. In each patient, we repeated diagnostic tests as required by the Copenhagen, European, Californian, and American-European Consensus Group (AECG) or ...
Hayes Don D Jr Department of Pediatrics, The Ohio State University, Columbus, OH, USA, - - 2014
Pulmonary hypertension (PH) commonly occurs in patients with cystic fibrosis (CF), but there is no current data regarding alterations of sleep in patients with PH. A single-center, retrospective review was performed in patients with advanced lung disease due to CF who completed both nocturnal polysomnography and right heart catheterization (RHC) ...
Cho Yeoungjee Y Department of Nephrology, Princess Alexandra Hospital, ARTS Building, Ipswich Rd, Woolloongabba, Queensland, Australia, - - 2014
The longevity of peritoneal dialysis (PD) is limited by high rates of technique failure, some of which stem from peritoneal membrane injury. 'Biocompatible' PD solutions have been developed to reduce damage to the peritoneal membrane. This review aimed to look at the benefits and harms of biocompatible PD solutions in ...
Dąbrowski Rafał R Instytut Kardiologii, Warszawa. - - 2014
Cardioversion of atrial fibrillation (AF) and maintenance of sinus rhythm are the basic strategies of treating AF patients. Precise data regarding the current practice of AF cardioversion in Europe in clinical practice are lacking. The primary objectives of this prospective observational study is to characterize patients and treatment patterns in ...
Zhu Xian X Department of Gastroenterology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, China, - - 2014
This study aims to evaluate the diagnostic accuracy of carbohydrate antigen 125 (CA125) in male patients for predicting gastrointestinal malignant diseases. One hundred twenty consecutive male patients underwent CA125 test after admission to the Department of Gastroenterology in Changhai Hospital, the Second Military Medical University, from April to June 2013. ...
Liu Junru J Department of Hematology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, - - 2014
The pathological changes of erythrocytes are detected at the nanometer scale, which is important for revealing the onset of diseases and diagnosis. The aim of this study is to examine the ultrastructural changes of erythrocytes in Waldenström macroglobulinemia (WM) at a nanometer scale. Blood samples were collected from two healthy ...
Burke Tomas R TR Ophthalmology, Royal United Hospital, Bath, Avon, Bath, Somerset, BA1 3NG, United - - 2014
Purpose: To quantify fundus autofluorescence (qAF) in patients with recessive Stargardt disease (STGD1). Methods: 42 STGD1 patients (ages: 7-52 years) with at least one confirmed disease-associated ABCA4 mutation were studied. Fundus AF images (488 nm excitation) were acquired with a confocal scanning laser ophthalmoscope equipped with an internal fluorescent reference ...
Jia Qian Q From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, - - 2014
It remains uncertain if impaired glucose regulation (IGR) as a predictor for stroke outcomes. This study aimed at observing the effect of IGR on the 1-year outcomes in Chinese patients with ischemic stroke. Patients with acute ischemic stroke were recruited consecutively in multihospitals across China. Oral glucose tolerance test was ...
Savey Lea - - 2014
Behcet's disease (BD) significantly increases morbidity and mortality. BD mainly affects young adults with a peculiar geographical distribution. It has been suggested that BD varies in its phenotypic expression in different ethnic groups. We investigated potential ethnicity-related differences relative to phenotype and prognosis of BD patients in a French multiethnic ...
Blasco Maria L ML Coronary Care Unit, University Clinic Hospital of Valencia, - - 2014
Acute glycometabolic derangement in non-diabetic patients with acute myocardial infarction (AMI) has been reported with discrepant prognostic results. The aim of the present study was to assess the prognostic impact of glycated haemoglobin (HbA1c) levels, reflecting long-term glycometabolic disturbance, in a population of patients without known diabetes mellitus. We examined ...
Natsume J J From the Departments of Pediatrics (J.N., N.M., H.K., N.I., H.T., K.M., T.N.) and Radiological and Medical Laboratory Sciences (K.K.), Nagoya University Graduate School of Medicine, Nagoya, Japan; Department of Neurology (K.I.), Aichi Children's Health and Medical Center, Obu, Japan; Department of Pediatrics (A.O.), Juntendo University Faculty of Medicine, Tokyo, Japan; Department of Pediatrics (T.K.), Anjo Kosei Hospital, Anjo, Japan; Department of Pediatrics (K.A.), Aichi Prefecture Medical Welfare Center of Aoitori, Nagoya, Japan; Morikawa Clinic (T.M.), Nagoya, Japan; and Faculty of Health and Medical Sciences (K.W.), Aichi Shukutoku University, Nagakute, - - 2014
Developmental and seizure outcomes in patients with cryptogenic West syndrome are variable. Our aim was to clarify the relationship between FDG-PET findings in infancy and long-term seizure and developmental outcome in cryptogenic West syndrome. From 1991 to 1999, we prospectively performed FDG-PET from the onset of cryptogenic West syndrome in ...
Guarneri Fabrizio F Department of Clinical and Experimental Medicine - Dermatology, University of Messina, Messina, - - 2014
Chronic urticaria (CU) is frequent, remains often idiopathic despite diagnostic efforts, and sometimes poorly responds to oral antihistamines and/or corticosteroids. We noticed that hyposideremia is often found in patients with chronic idiopathic urticaria poorly responsive to usual treatments (prCIU), and oral iron therapy is frequently associated to improvement or resolution ...
Lim Won Hee WH a Associate Professor, Dental Research Institute and Department of Orthodontics, School of Dentistry, Seoul National University, Seoul, - - 2014
Abstract Introduction: To investigate dentofacial characteristics of orthodontic patients with centric relation (CR)-maximum intercuspation (MI) discrepancy and to analyze changes in dentofacial characteristics between CR and MI positions in these patients using lateral cephalograms. Materials and Methods: Adult female patients were classified into two groups: large CR-MI discrepancy (greater than ...
Corey K E KE Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Weight Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, - - 2014
We evaluated the prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in 27 adolescents referred for weight loss surgery (WLS). On biopsy, 18 patients (66.7%) had NAFLD, and of those, 10 (37.0%) had NASH and 11 (40.7%) had fibrosis. Insulin, HbA1C and homeostatic model assessment of insulin ...
Szymański Filip M FM I Katedra i Klinika Kardiologii, Warszawski Uniwersytet Medyczny. - - 2014
Obstructive sleep apnea (OSA) and atrial fibrillation (AF) are two conditions highly prevalent in the general population. OSA is known to cause hemodynamic changes, oxidative stress, and endothelial damage, and therefore promote vascular and heart remodelling which results in triggering and exacerbating AF. Coexistence of OSA and AF influences course ...
Yang Paul P Casey Eye Institute, Oregon Health & Science University, - - 2014
IMPORTANCE While older children and adults with achromatopsia have been studied, less is known of young children with achromatopsia. OBJECTIVES To characterize the macular and foveal architecture of patients with achromatopsia during early childhood with handheld spectral-domain optical coherence tomographic imaging and to make phenotype-genotype correlations. DESIGN, SETTING, AND PARTICIPANTS ...
Saito Tsukasa T Department of Internal Medicine, Cardiovascular, Respiratory and Neurology Division, Asahikawa Medical University, Asahikawa, Hokkaido, Japan. Electronic address: - - 2014
Atrial fibrillation (AF) is a cardiac arrhythmia that does not infrequently induce ischemic strokes; however, little research has been reported on focal cerebral microangiopathic lesions in patients with AF. Recently cerebral microbleeds (CMBs) have been noticed for their potential implication in cerebral small vessel disease. Therefore, we had 2 goals ...
Costa Ana S AS Department of Neurology, Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen University Hospital, Aachen, Germany; Jülich Aachen Research Alliance (JARA)-Translational Brain Medicine, Aachen and Jülich, - - 2014
Cognitive impairment in hemodialysis (HD) patients is frequent and mediated by several factors. It is unclear which patients are more susceptible to cognitive variations around the dialysis cycle and which clinical factors may play a mediator role. We aimed to answer these issues by investigating intraindividual changes within the dialysis ...
Ikeura Tsukasa T From the *The Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan; †Department of Pathology, Odense University Hospital, Odense, Denmark; Departments of ‡Pathology, §Radiology, and ∥Medicine, Pancreas Center, University of Verona, Verona, Italy; and ¶Department of Pathology, University of Kiel, Kiel, - - 2014
The objective of this study was to compare the preoperative diagnosis by International Consensus Diagnostic Criteria (ICDC) with histological diagnosis in patients with focal autoimmune pancreatitis (AIP) who underwent surgery. Thirty patients (type 1 AIP in 23 and type 2 AIP in 7) with a diagnosis of AIP based on ...
Chauhan Monika M Department of Pediatrics, Division of Critical Care, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan. Electronic address: - - 2014
Temporary epicardial pacing wires are commonly placed in patients undergoing surgery for congenital heart disease. Though often helpful, these wires are not without risk. We aimed to identify characteristics that would obviate placement of temporary epicardial pacing wires in this patient population. A prospective observational study was performed on patients ...
Depew Zachary S ZS Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, - - 2014
Nonspecific pleuritis (NSP) is a frequent diagnosis after parietal pleural biopsy, but the clinical significance of this finding and need for further follow-up have not been firmly established. Previous reports suggest that 5% to 25% of patients with NSP are subsequently diagnosed with pleural malignancy. Our pathology database was queried ...
Koutsis Georgios G Neurogenetics Unit, 1st Department of Neurology, University of Athens Medical School, Eginition Hospital, Athens, Greece. Electronic address: - - 2014
To address diagnostic and prognostic issues in patients with late-onset Huntington's disease (HD). We analyzed a cohort of 41 late-onset (≥60 years) HD patients and compared them to 39 late-onset patients referred for HD testing that were negative for the HD-expansion and to 290 usual-onset (20-59 years) HD patients. Disease ...
Araten David J - - 2014
PNH is associated with abdominal vein thrombosis, which can cause splenomegaly and hypersplenism. The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding risk. Splenectomy could alleviate thrombocytopenia and reduce portal pressure, but it can cause post-operative thromboses and opportunistic ...
Baum S S Department of Dermatology, Tel Hashomer, and The Sackler School of Medicine, Tel Aviv - - 2014
Onchocerciasis is an infectious disease caused by the filaria Onchocerca volvulus. Very little is known regarding onchocerciasis imported from endemic to non-endemic areas. To evaluate pruritic dermatitis simulating atopic dermatitis in Ethiopian immigrants in Israel. A retrospective study on 27 Ethiopian immigrants to Israel was conducted. Demographics and clinical and ...
Usui Shingo S Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, - - 2014
We have reported that second-generation colon capsule endoscopy (CCE-2) might be feasible for assessing the severity of mucosal inflammation in ulcerative colitis (UC). However, because of the low rate (69%) of complete evaluation of the colon and owing to inadequate cleansing. We believe that the method of bowel preparation could ...
Chiew A L AL Department of Emergency Medicine, Clinical and Experimental Toxicology Unit, Prince of Wales Hospital , Randwick, NSW , - - 2014
Context. Dabigatran etexilate is one of the newer oral anticoagulants and a direct thrombin inhibitor. Concerns regarding dabigatran's use include its lack of validated laboratory markers for measuring its anticoagulation effect, the impact of renal impairment on its clearance, and the lack of effective strategies for reversal of anticoagulation. Hemodialysis ...
Metternich B B Epilepsy Center, University Medical Center Freiburg, Breisacher Str. 64, 79106, Freiburg, Germany, - - 2014
Testing of verbal fluency is currently part of standard presurgical neuropsychological assessment for patients with focal epilepsy. However, to date no systematic review has been conducted on semantic (SVF) and phonemic verbal fluency (PVF) in this patient group. The present review compares verbal fluency between healthy control subjects and subgroups ...
Buiten M S MS Department of Cardiology, Leiden University Medical Center (LUMC), , Leiden, The - - 2014
Atrial fibrillation (AF) is common in dialysis patients and is associated with increased morbidity and mortality. The pathophysiology may be related to common risk factors for both AF and renal disease or to dialysis-specific factors. The purpose of this study was to determine whether and how AF onset relates to ...
Cavalier Etienne - - 2014
Abstract Background: Standardization of parathyroid hormone (PTH) assays is a major issue, especially in hemodialyzed (HD) patients. Two automated third generation PTH assays (Roche Elecsys and DiaSorin Liaison) are now available. These assays are specific for the (1-84) PTH and do not cross-react with the (7-84) fragment, contrary to second ...
Abe Ayumi A Department of Otolaryngology, Sapporo Medical University School of Medicine , Sapporo , - - 2014
Objectives. Mikulicz's disease (MD) is an immunoglobulin (Ig) G4-related disease with systemic symptoms. Submandibular gland (SMG) biopsy is recommended for patients with possible IgG4-related MD for accurate differential diagnosis; however, it is difficult for certain patients to undergo this procedure. In contrast, labial salivary gland (LSG) biopsy is more convenient. ...
Kimura Koichi K Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, - - 2014
The clinical presentations of gastrointestinal bleeding (GIB) occurring after living donor liver transplantation (LDLT) have not been fully described. We performed a retrospective analysis of 297 LDLT cases. Nineteen patients (6.4%) experienced GIB after LDLT. The etiology of GIB included bleeding at the jejuno-jejunostomy following hepatico-jejunostomy (n = 13), peptic ...
Bhidayasiri Roongroj R Chulalongkorn Center of Excellence on Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Bangkok, 10330, Thailand, - - 2014
While nocturnal disturbances of Parkinson's disease (PD) are increasingly recognized as being part of a continuum that includes daytime manifestations, there is still little analysis in the medical literature that assesses these complex phenomena in patients with atypical (AP) and vascular parkinsonisms (VP). The objective of our study was to ...
Tekce Buket Kin BK Department of Medical Biochemistry, Faculty of Medicine, Abant Izzet Baysal University, Bolu, - - 2014
It is not possible to diagnose acute kidney injury (AKI) in early stages with traditional biomarkers. Kidney injury molecule-1 (KIM-1) is a novel biomarker promising the diagnosis of AKI in early stages. We studied whether urinary and serum KIM-1 (KIM-1U and KIM-1S) concentrations were useful in predicting cisplatin-induced AKI in ...
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