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Huang Cheng-Hsien CH Department of Pediatrics, Taipei City Hospital, Yang Ming Branch, Taipei, - - 2014
To clarify the relationship between neuroimaging findings, neuropsychiatric comorbidities, and epilepsy in patients with tuberous sclerosis complex (TSC) in Taiwan. Medical records from 32 patients with TSC were retrospectively reviewed, including mutational analysis, neuroimaging findings, electroencephalogram findings, and neuropsychiatric comorbidities. Of these patients, six (18.75%) were diagnosed to have autism ...
Mumma Bryn E BE Department of Emergency Medicine, University of California Davis, Sacramento, - - 2014
Nitroglycerin ointment is commonly used in the treatment of emergency department (ED) patients with suspected acute heart failure (AHF) or suspected acute coronary syndrome (ACS), but its hemodynamic effects in this population are not well described. Our objective was to assess the effect of nitroglycerin ointment on mean arterial pressure ...
Luigetti Marco M Dept. of Geriatrics, Neurosciences & Orthopedics, Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: - - 2014
Classic clinical manifestations of HNPP are characterized by recurrent painless mononeuropathies, but a minority of patients present with an atypical clinical pattern, including CMT-like neuropathy, acute or chronic inflammatory demyelinating neuropathy-like polyneuropathy, and carpal tunnel syndrome. Electrophysiological examination plays a central role in the diagnosis of HNPP, disclosing a non-uniform ...
Tsai Jeng-Dau JD Department of Pediatrics, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo North Road, Taichung, 402, - - 2014
Renal manifestations of tuberous sclerosis complex (TSC) occur with a high frequency and a wide range of severity. The onset and complications of each affected organ depend on the age. This study aimed to investigate the associations between comorbidities, frequency, and size of cysts/angiomyolipomas of TSC and the patients in ...
Shahangian S S Department of Pulmonary and Critical Care, University of California, Los Angeles, Westwood, USA, - - 2014
Hepatopulmonary syndrome (HPS) is characterized by impaired oxygenation due to pulmonary vascular dilatation in patients with end-stage liver disease. At our center, we identified 29 patients who were listed for liver transplantation (LT) with a model for end-stage liver disease exception for HPS between 2001 and 2012. Five of these ...
Sharma Neel Kamal NK Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, - - 2014
Age-related macular degeneration (AMD) is a devastating disease that results in irreversible central vision loss. TLRs signaling pathway has been found to play an important role in AMD pathogenesis as evidenced by several studies. The objective of the study was to determine the single nucleotide polymorphism (SNP) changes in TLR3 ...
Boghosian M M Mechanical, Materials, and Aerospace Engineering Department, Illinois Institute of Technology, Chicago, IL, United States. Electronic address: - - 2014
The care and outcome of patients with end stage renal disease (ESRD) on chronic hemodialysis is directly dependent on their hemodialysis access. A brachiocephalic fistula (BCF) is commonly placed in the elderly and in patients with a failed lower-arm, or radiocephalic, fistula. However, there are numerous complications such that the ...
Burri Emanuel - - 2014
European Panel on the Appropriateness of Gastrointestinal Endoscopy (EPAGE) criteria have been developed to increase diagnostic yield, but their predictive value is limited. We investigated the incremental diagnostic value of faecal calprotectin to EPAGE criteria. In a post-hoc analysis of a prospective study, EPAGE criteria were applied to 298 of ...
Koeppen Susanne S Department of Neurology, Medical School, University of Duisburg-Essen, Hufelandstraße 55, 45122, Essen, Germany, - - 2014
The aim of this study was to analyze the occurrence of neuromuscular symptoms in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) for treatment of malignant hematopoietic disease. Among 247 outpatients after allogeneic HSCT, we conducted a prospective non-interventional study between July 2011 and August 2013. During follow-up visits, clinical ...
Schoonman G G GG Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands; Department of Neurology, Medisch Centrum Haaglanden, The Hague, The - - 2014
Mild traumatic brain injury (mTBI) is a common neurological disorder. Whether oral anticoagulation (OAC) use is a risk factor for secondary deterioration in mTBI patients after a normal computed tomography (CT) scan is unclear. Therefore data were retrospectively collected on patients with mTBI who used OAC to determine the incidence ...
Lei C C Stroke Clinical Research Unit, Department of Neurology, West China Hospital, Sichuan University, Sichuan, - - 2014
Evidence suggests that elevated thyroid function and elevated levels of thyroid autoantibodies are associated with risk of moyamoya disease (MMD). Therefore a meta-analysis of all available evidence was performed, including unpublished data from our own center, in order to assess this association. Major literature databases were reviewed without language restrictions ...
Sellner J J Department of Neurology, Christian-Doppler-Klinik, Paracelsus Medical University, Salzburg, Austria; Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, - - 2014
The neurological outcome of acute encephalitis can be devastating and early prognosis remains difficult. Biomarkers that quantify the extent of early brain injury are needed to improve the prognostic accuracy and aid patient management. Our objective was to assess whether cerebrospinal fluid (CSF) protein biomarkers of neuroaxonal and glial cell ...
Jiang Wanli W Department of Cardiovascular Surgery,Renmin Hospital,Wuhan University,Wuhan, - - 2014
Thoracic aortic dissection is a catastrophic acute disease with a high postoperative mortality , and few predictor is known for the prognostic. This study evaluated whether S100A12 could be a promising marker in thoracic aortic dissections (TAD). A total of 72 patients with DeBakey Tpye I TAD and 18 heart ...
Pokushalov Evgeny E State Research Institute of Circulation Pathology, Novosibirsk, Russia. Electronic address: - - 2014
The potential role of renal denervation (RD) in patients with AF and less severe hypertension is unknown. The aim of this study was to assess the potential role of RD as an adjunct to pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) and moderate resistant or severe resistant ...
Süer Evren E Department of Urology, Ibn-i Sina Hospital, Ankara University, Samanpazarı-Ankara, 06100, Turkey, - - 2014
The purpose of the study was to investigate the effect of ABO blood groups and Rhesus (Rh) factor on prognosis of patients undergoing radical cystectomy. In this study, total number of 290 patients who underwent radical cystectomy between January 1990 and September 2012 were evaluated retrospectively. Patients were grouped as ...
Koumakis E E Department of Rheumatology A, Cochin Hospital, APHP, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France, - - 2014
In this study, we show that successful parathyroidectomy is followed at 1 year by a significant individual bone mineral density (BMD) gain in nearly half of normocalcemic PHPT patients with reduced bone mass. Alkaline phosphatase levels above median were identified as an independent predictor of individual BMD gain in normocalcemic PHPT ...
Untereiner Valérie V Université de Reims Champagne-Ardenne, MéDIAN-Biophotonique et Technologies pour la Santé, UFR de Pharmacie, 51 rue Cognacq-Jay, 51096 REIMS cedex, France; CNRS UMR7369, Matrice Extracellulaire et Dynamique Cellulaire, MEDyC, Reims, - - 2014
This study aimed at determining whether FTIR spectroscopy is able to distinguish bile samples from patients with and without malignant biliary strictures. Bile samples were collected in 19 patients with malignant biliary strictures and 38 with benign biliary diseases during endoscopic procedures. FTIR spectra were acquired on dried drops of ...
Nardone Raffaele R Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University and Center for Cognitive Neuroscience, Salzburg, Austria, - - 2014
Short-latency afferent inhibition (SAI) technique gives the opportunity to non-invasively test an inhibitory circuit in the human cerebral motor cortex that depends mainly on central cholinergic activity. Important SAI abnormalities have been reported in both patients with Alzheimer disease (AD) and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ...
Salgado Cláudia M CM a University of PIttsburgh School of Medicine, - - 2014
Abstract Nevocytes (NC) and mastocytes (MC) have different progenitors but share stem-cell factor as regulator/activator of NC, and for differentiation/proliferation of MC. Both cell types express SCF receptor CD117. We hypothesize that Large/Giant Congenital Mela-nocytic Nevi (L/GCMN) may associate with MC hyperplasia. Design: 49 L/GCMN, 12 samples from uninvolved skin ...
Kim Geon Ha GH From the Department of Neurology (G.H.K., J.H.J.), Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul; Departments of Neurology (J.H.L.) and Nuclear Medicine (S.J.O., J.S.K.), Asan Medical Center, University of Ulsan College of Medicine, Seoul; Departments of Neurology (S.W.S., B.S.Y., H.C., H.J.K., J.H.C., D.L.N.), Nuclear Medicine (Y.S.C., K.H.L.), and Radiology (S.T.K.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul; Department of Neurology (Y.N.), Gachon University Gil Medical Center, Incheon; and Department of Neurology (C.W.Y.), Inha University Hospital, Inha University School of Medicine, Incheon, - - 2014
The purpose of this study was to propose new criteria for differentiating Pittsburgh compound B (PiB)-negative from PiB-positive subcortical vascular dementia (SVaD) using clinical and MRI variables. We measured brain amyloid deposition using PiB-PET in 77 patients with SVaD. All patients met DSM-IV criteria for vascular dementia and had severe ...
Kanth Aditi M AM Department of Surgery, Division of Vascular Surgery, SUNY at Stony Brook, Stony Brook, NY, - - 2014
This study was performed to precisely define the underlying pathophysiology in patients with active venous ulcers. A PubMed search was conducted from 1991 to 2013 to select papers reporting the anatomic and physiologic etiology of ulceration in CEAP Class 6 patients. Studies which did not decipher between active and healed ...
Coppadoro Andrea - - 2014
Biofilm accumulates within the endotracheal tube (ETT) early after intubation. Contaminated secretions in the ETT are associated with increased risk for microbial dissemination in the distal airways and increased resistance to airflow. We evaluated the effectiveness of micro computed tomography (MicroCT) for the quantification of ETT inner volume reduction in ...
Stefanini Giulio G GG Department of Cardiology, Bern University Hospital, Bern 3010, - - 2014
The aim of this study was to evaluate whether coronary artery disease (CAD) severity exerts a gradient of risk in patients with aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI). A total of 445 patients with severe AS undergoing TAVI were included into a prospective registry between 2007 and ...
Kohi Maureen P MP Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, - - 2014
Right adrenal vein (RAV) catheterization can be a very challenging step in adrenal venous sampling (AVS). Visualization of the inferior emissary vein (IEV) may be an indication of successful RAV catheterization. To compare the rate of successful RAV sampling in the presence of the IEV. Retrospective review of all consecutive ...
Sternick Eduardo Back EB Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, Brazil; Instituto de Pós-Graduação, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, - - 2014
A 28-year-old male patient with a 3-year history of recurrent tachycardia was referred for electrophysiologic evaluation and catheter ablation. The patient had no other co-morbidities. Propafenone was discontinued 7 days before admission. This article is protected by copyright. All rights reserved.
Kaski D D Department of Neuro-otology, Imperial College London, Charing Cross Hospital, London W6 8RF, United Kingdom. Electronic address: - - 2014
Gait disturbance in patients with Parkinson's disease remains a therapeutic challenge, given its poor response to levodopa. Dance therapy is of recognised benefit in these patients, particularly partnered dance forms such as the tango. In parallel, non-invasive brain stimulation has begun to show promise for the rehabilitation of patients with ...
Deguchi Ichiro I Department of Neurology, Saitama Medical University International Medical Center, Saitama, Japan. Electronic address: - - 2014
The presence or absence of the penumbra area is important when performing reperfusion therapy in patients with acute ischemic stroke. As a predictor of this penumbra area, magnetic resonance angiography (MRA)-diffusion-weighted imaging (DWI) mismatch is attracting attention. The usefulness of MRA-DWI mismatch (MDM) using the DWI-Alberta Stroke Program Early Computed ...
Di Stefano Rossella R aDepartment of Surgical, Medical and Molecular Pathology and Critic Area bDepartment of Clinical and Experimental Medicine, Psychiatry Sector, University of Pisa, Pisa cUnit of Cardiology, Ospedale S. Andrea, La Spezia dCardio-Respiratory Department, Ospedale Campo di Marte, Lucca eUnit of Cardiology, USL5 Sarzana (SP), Italy *Rossella Di Stefano and Francesca Felice contributed equally to the writing of this - - 2014
Depression has been identified as a risk factor for an adverse prognosis and reduced survival in patients with acute coronary syndrome (ACS). The number of endothelial progenitor cells (EPCs) is an independent predictor of clinical outcomes in patients with ACS. The aim of this study was to evaluate the impact ...
Yang Shuangshuang S Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. - - 2014
Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) is considered as an effective predictor for patients with heart failure (HF), while a strong body of evidence has found its utility in inflammatory diseases. It is difficult to differentiate HF and HF coexisting with other inflammations by measuring NT-proBNP. The aim of this ...
Jacob Ron R Department of Pediatrics B, Meyer Children's Hospital of Haifa, Rambam Medical Center, Faculty of Medicine, Technion, Haifa, - - 2014
Respiratory disease is a common reason for hospitalization and mortality in persons with severe intellectual and developmental disability. Capnography is the measurement and numerical display of end-tidal carbon dioxide (EtCO2). This was a prospective, case controlled, cross sectional study to assess differences of baseline EtCO2 values between neurologically impaired patients ...
Celikbilek Mehmet M Department of Gastroenterology, Bozok University Medical School, Yozgat, - - 2014
Blood neutrophil-to-lymphocyte (N/L) ratio is an indicator of the overall inflammatory status of the body, and an alteration in N/L ratio may be found in patients with familial Mediterranean fever (FMF). The aim of this study was to investigate the interrelationship between N/L ratio and FMF. One hundred and fifteen ...
Cushen Samantha J SJ *Department of Food & Nutritional Sciences ∥School of Mathematical Science, University College Cork †Department of Medical Oncology, Mercy & Cork University Hospitals §Department of Radiology, Mercy University Hospital, Cork ‡Department Medical Oncology, Adelaide & Meath Hospital incorporating National Children's Hospital, Tallaght, - - 2014
Sunitinib is a standard first-line option for metastatic renal cell carcinoma (mRCC). Body composition is a prognostic factor in cancer patients and patients with loss of skeletal muscle mass and fat-free mass (FFM) are prone to dose-limiting toxicity (DLT) during targeted drug therapy. We investigated whether body composition by computed ...
Leyhe Thomas T Center of Old Age Psychiatry, Psychiatric University Hospital, Basel, Switzerland. Electronic address: - - 2014
Hashimoto's thyroiditis (HT) is the most frequent cause of hypothyroidism in areas with sufficient iodine intake. While the impact of thyroid function on mood and cognition is well known, only in the recent years, an increasing number of studies report on the association of HT with cognitive and affective disturbances ...
Werner Christian C Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Homburg/Saar, - - 2014
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL-cholesterol receptor homeostasis and emerges as a therapeutic target in the prevention of cardiovascular (CV) disease. This prospective cohort study analyzes risk prediction with PCSK9 serum concentrations in patients with stable coronary artery disease (CAD) on statin treatment. Fasting PCSK9 ...
Masuda Hiroshi H Department of Cardiovascular Medicine, Juntendo University, School of Medicine, Tokyo, - - 2014
Rheumatoid arthritis (RA) increases the mortality and morbidity of cardiovascular disease (CVD). However, the relationship between RA and the risk of CVD in the Japanese population remains unclear. This study comprised 571 RA patients who were admitted to Juntendo University Hospital from January 1990 to December 2000. Cardiovascular events (CVEs) ...
Carvalho Ana Teresa P AT Ana Teresa P Carvalho, Barbara C Esberard, Renata S B Fróes, Ana B Grinman, Disciplina de Gastroenterologia e Endoscopia Digestiva, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, - - 2014
To analyze the prevalence of thiopurine-methyltransferase (TPMT) genotypes and their association with drug toxicity in inflammatory bowel disease (IBD) patients from southeastern Brazil. A total of 219 consecutive patients with IBD, of which 146 had Crohn's disease and 73 had ulcerative colitis, regularly seen at the outpatient unit of the ...
Watabe Hiroaki H Department of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, - - 2014
The association between contrast-induced acute kidney injury (CI-AKI) and chronic kidney disease (CKD) in patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI) has not been fully reported. We evaluated the association of CI-AKI on cardiovascular events in ACS patients with CKD. A total of 1059 ACS ...
Izuhara Y Y Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, - - 2014
In steroid-naive patients with asthma, several gene variants are associated with a short-term response to inhaled corticosteroid (ICS) treatment; this has mostly been observed in Caucasians. However, not many studies have been conducted for other ethnicities. Here, we aimed to determine the relationship between the annual decline in forced expiratory ...
Khow Kareeann S F KS Department of General Medicine, Flinders Medical Centre , Adelaide , Australia - - 2014
Abstract Elevated creatine kinase (hyper-CKemia) has been observed in small number of patients with hyponatremia. This study evaluated the features and outcomes of patients admitted with hyponatremia complicated by hyper-CKemia. Patients admitted with hyponatremia and concurrently found to have elevated creatine kinase (CK) of above 375 IU/L (male) or 225 IU/L (female), ...
Firinci Fatih F Department of Pediatrics, Dokuz Eylul University School of Medicine , İzmir , Turkey - - 2014
Abstract Aim: To assess the relationship between mesangial hypercellularity in various childhood nephropathies and clinical and laboratory parameters. Methods and patients: The reports of the renal biopsies were evaluated retrospectively. The patients with diagnosis of IgA nephropathy (isolated and Henoch-Schönlein nephritis), IgM nephropathy, or isolated mesangial proliferative glomerulonephritis were included. ...
Rupa-Matysek Joanna J Department of Haematology, Poznan University of Medical Sciences, Szamarzewskiego 84, 60-569, Poznan, Poland, - - 2014
Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked venous thromboembolism. The aim of our study was to evaluate MPV in patients with confirmed antiphospholipid antibody syndrome (APS) and to identify the correlation between the value of MPV and the ...
Plešivčnik Novljan Martina M Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, - - 2014
The objective of the study is to compare the longitudinal performance of different classification criteria for primary Sjögren's syndrome (SS) in a cohort of patients previously diagnosed with primary SS. In each patient, we repeated diagnostic tests as required by the Copenhagen, European, Californian, and American-European Consensus Group (AECG) or ...
Hayes Don D Jr Department of Pediatrics, The Ohio State University, Columbus, OH, USA, - - 2014
Pulmonary hypertension (PH) commonly occurs in patients with cystic fibrosis (CF), but there is no current data regarding alterations of sleep in patients with PH. A single-center, retrospective review was performed in patients with advanced lung disease due to CF who completed both nocturnal polysomnography and right heart catheterization (RHC) ...
Cho Yeoungjee Y Department of Nephrology, Princess Alexandra Hospital, ARTS Building, Ipswich Rd, Woolloongabba, Queensland, Australia, - - 2014
The longevity of peritoneal dialysis (PD) is limited by high rates of technique failure, some of which stem from peritoneal membrane injury. 'Biocompatible' PD solutions have been developed to reduce damage to the peritoneal membrane. This review aimed to look at the benefits and harms of biocompatible PD solutions in ...
Dąbrowski Rafał R Instytut Kardiologii, Warszawa. - - 2014
Cardioversion of atrial fibrillation (AF) and maintenance of sinus rhythm are the basic strategies of treating AF patients. Precise data regarding the current practice of AF cardioversion in Europe in clinical practice are lacking. The primary objectives of this prospective observational study is to characterize patients and treatment patterns in ...
Zhu Xian X Department of Gastroenterology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, China, - - 2014
This study aims to evaluate the diagnostic accuracy of carbohydrate antigen 125 (CA125) in male patients for predicting gastrointestinal malignant diseases. One hundred twenty consecutive male patients underwent CA125 test after admission to the Department of Gastroenterology in Changhai Hospital, the Second Military Medical University, from April to June 2013. ...
Liu Junru J Department of Hematology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, - - 2014
The pathological changes of erythrocytes are detected at the nanometer scale, which is important for revealing the onset of diseases and diagnosis. The aim of this study is to examine the ultrastructural changes of erythrocytes in Waldenström macroglobulinemia (WM) at a nanometer scale. Blood samples were collected from two healthy ...
Burke Tomas R TR Ophthalmology, Royal United Hospital, Bath, Avon, Bath, Somerset, BA1 3NG, United - - 2014
Purpose: To quantify fundus autofluorescence (qAF) in patients with recessive Stargardt disease (STGD1). Methods: 42 STGD1 patients (ages: 7-52 years) with at least one confirmed disease-associated ABCA4 mutation were studied. Fundus AF images (488 nm excitation) were acquired with a confocal scanning laser ophthalmoscope equipped with an internal fluorescent reference ...
Jia Qian Q From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, - - 2014
It remains uncertain if impaired glucose regulation (IGR) as a predictor for stroke outcomes. This study aimed at observing the effect of IGR on the 1-year outcomes in Chinese patients with ischemic stroke. Patients with acute ischemic stroke were recruited consecutively in multihospitals across China. Oral glucose tolerance test was ...
Savey Lea - - 2014
Behcet's disease (BD) significantly increases morbidity and mortality. BD mainly affects young adults with a peculiar geographical distribution. It has been suggested that BD varies in its phenotypic expression in different ethnic groups. We investigated potential ethnicity-related differences relative to phenotype and prognosis of BD patients in a French multiethnic ...
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