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Results 251 - 300 of 17259
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Bartels Janina - - 2014
Chemokines such as MIP-3beta/CCL19 are important factors in the mechanism of cell migration and pathogenesis of central nervous system (CNS) inflammatory reactions. The hypothesis of this study is that CCL19, also known as MIP-3beta, is involved in the pathogenesis of inflammatory and non-inflammatory CNS diseases of dogs. Experiments were performed ...
Giannopoulos Georgios G Cardiac Catheterization Laboratory, Department of Cardiology, Athens General Hospital "G. Gennimatas", Athens, Greece; Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA. Electronic address: - - 2014
Red blood cell and platelet microparticles (RBCm and PLTm, respectively) have drawn research attention as to their potential prothrombotic and vasoconstrictive effects in experimental settings. However, the relevance of circulating microparticles in clinical settings is largely undetermined. Circulating microparticles were quantified with a flow cytometric method in blood samples from ...
Salinas-Torres Victor M VM Department of Medical Genetics, Civil Hospital of Guadalajara Fray Antonio Alcalde and University of Guadalajara, Hospital No. 278, Col. El Retiro, 44280,, Guadalajara, Jalisco, Mexico, - - 2014
In this series the authors evaluate clinical, cytogenetic, environmental and inheritance characteristics of neonates with VACTERL association. Twenty-six patients were diagnosed with VACTERL association and had a normal somatometric profile. Fifty-eight percent cases were males. The frequency of each component was: vertebral defects (V), 77 %; anal atresia (A), 62 %; tracheo-esophageal ...
Poletti Michele M Department of Mental Health and Pathological Addiction, AUSL of Reggio Emilia, Reggio Emilia, Italy, - - 2014
An overactive striatal dopaminergic neurotransmission is described in psychosis and may be associated with a state of aberrant salience attribution. This pilot psychometric study investigated if features suggestive of an aberrant salience state, a condition of psychosis proneness, are associated with dopamine replacement therapy in patients with early Parkinson's disease ...
Topac H H Konya Military Hospital, Department of Urology, Konya, Turkey - - - 2014
To determine the duration of antibiotherapy to decrease TPSA levels to normal ranges in patients without prostatitis symptoms but with total PSA levels 4.01--9.9 ng/dl. A total of 129 male patients were enrolled and divided into either study group (n:102) or control group (n:27). Study group received 21 days course ...
Grapsa E E Nephrology Department, Aretaieion University Hospital, Athens, Greece - - - 2014
The aim of the study was to assess whether age, gender and the primary renal disease are associated with differences in the type of first vascular access placement. We reviewed the records of 145 patients on hemodialysis (HD) 44 females and 101 males with a mean age of 64±14.5 years, ...
Sano Natsuki N Department of Orthodontics, The Nippon Dental University School of Life Dentistry at Niigata, 951-8580, Hamaura-chou 1-8, Chuuou-ku, Niigata, Japan, - - 2014
Cases of congenitally missing and delayed eruption of the maxillary first molar are rare. However, in recent years, we have experienced cases of suspected delayed eruption of or congenitally missing first molars. The purpose of this study was to analyze the formation of delayed erupted maxillary first molars (M1) (>2 ...
Chan S Y S SY The SH Ho Urology Centre, Division of Urology, Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong - - 2014
To investigate the incidence of deep vein thrombosis (DVT) in Chinese patients undergoing robotic-assisted laparoscopic radical prostatectomy (RALP) for prostate cancer and the need for prophylactic anticoagulation. From August 2007 to September 2010, patients with prostate cancer undergoing RALP in our center were prospectively recruited for the study. Perioperative parameters, ...
Borghi A A Sezione di Dermatologia e Malattie Infettive, Dipartimento di Scienze Mediche, Università degli Studi di Ferrara, Italia - - - 2014
Estimates of malignant melanoma (MM) incidence and prognosis vary widely. The present study was performed to analyze epidemiologic and prognostic aspects of primary MM mainly in relation to tumor thickness. We conducted a retrospective study on a cohort of 435 patients with diagnosis of primary MM between 1997 and 2011. ...
Sieminska Alicja - - 2014
Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a rare, mild inflammatory pulmonary disorder that occurs almost exclusively in current or former heavy smokers, usually between the third and sixth decades, most likely with no gender predilection. The onset is usually insidious with exertional dyspnea and persistent cough, which may be ...
Bennett-Back Odeya O Division of Neurology - - 2014
Object Porencephalic cyst/encephalomalacia (PC/E) is a brain lesion caused by ischemic insult or hemorrhage. The authors evaluated magnetoencephalography (MEG) spike sources (MEGSS) to localize the epileptogenic zone in children with intractable epilepsy secondary to PC/E. Methods The authors retrospectively studied 13 children with intractable epilepsy secondary to PC/E (5 girls ...
Tzogias Leonidas L St. Vincent Medical Group, Indianapolis, - - 2014
-Definitive diagnosis of bilateral bundle branch delay/block (BBBD) may be made when catheter induced right bundle branch block (RBBB) develops in patients with baseline left bundle branch block (LBBB). We hypothesized that a RBBB pattern with absent S waves in leads I and aVL will identify BBBD. -Fifty patients developing ...
Pollak Lea L Department of Neurology, Assaf Harofeh Medical Center, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel - - 2014
In view of patients' recurrent complaints, we were interested in investigating the frequency and headache characteristics in patients during a benign paroxysmal positional vertigo (BPPV) cluster. Patients with BPPV treated at an outpatient dizziness clinic were interviewed about the presence of headache; its quality, localization, severity, time course, and aggravating ...
Lima-Silva Thais Bento TB Neurology Department, University of São Paulo, São Paulo, - - 2014
There is limited information about the functional profile of behavioral variant frontotemporal dementia (bvFTD). To compare direct and indirect assessments of activities of daily living (ADLs) in bvFTD and Alzheimer disease (AD) and their relationship with cognitive performance. In all, 20 patients with bvFTD, 30 patients with AD, and 34 ...
Goehler Alexander A Yale University, New Haven, CT; Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA - - 2014
-Pulmonary nodules (PN) are often incidentally detected during coronary CT angiography (CCTA) which is increasingly used to evaluate patients with chest pain symptoms. However, the efficiency of following up on incidentally detected PN is unknown. -We determined demographic and clinical characteristics of stable symptomatic patients referred for CCTA in whom ...
Santos Berenice L BL Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, - - 2014
to characterize the clinical, laboratory, and anthropometric profile of a sample of Brazilian patients with glycogen storage disease type I managed at an outpatient referral clinic for inborn errors of metabolism. this was a cross-sectional outpatient study based on a convenience sampling strategy. Data on diagnosis, management, anthropometric parameters, and ...
Greywoode Ruby R Department of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, - - 2014
To investigate a recent association between the use of the angiotensin receptor-blocker (ARB) olmesartan and a severe enteropathy resembling celiac disease. We searched our endoscopy database for all outpatient esophagogastroduodenoscopy (EGD) or colonoscopy examinations in patients aged at least 50 years during the period January 1, 2007, to March 31, ...
Margallo Victor S VS Hypertension Program, University Hospital Clementino Fraga Filho, Medical School, Universidade Federal do Rio de Janeiro, - - 2014
Obstructive sleep apnea (OSA) is strongly associated with resistant hypertension. The Berlin questionnaire is the most widely used screening tool to identify patients at high risk of having OSA. The objective was to test the diagnostic accuracy of the Berlin questionnaire in detecting OSA in resistant hypertensive patients. A cross-sectional ...
Esposito Francesco F *Department of Radiology - "Santobono-Pausilipon" Hospital - Naples- Italy †Department of Radiology - University Hospital "Federico II" - Naples - Italy ‡Section of Ultrasonography and Interventional Ultrasound - "D. Cotugno" Hospital - Naples - Italy §4 Department of Radiology -Santa Maria alla Gruccia Hospital - zona Valdarno - Azienda USL8 Arezzo - - - 2014
Midgut volvulus with malrotation is typical in newborns. We present our experience to underline the importance of suspecting midgut volvulus as cause of abdominal pain also beyond infancy, particularly in relationship with malrotation, and the relevance of ultrasonographic (US) signs in its diagnosis. 34 patients (10 M, 24 F; aged between ...
Tujios Shannan R SR Division of Digestive and Liver Diseases, UT Southwestern Medical Center at Dallas, - - 2014
Patients with acute liver failure (ALF) frequently develop renal dysfunction, yet its overall incidence and outcomes have not been fully assessed. We investigated the incidence of acute kidney injury (AKI) among patients with ALF, using defined criteria to identify risk factors and to evaluate its effect on overall outcomes. We ...
Sana Aria A Departments of Gastroenterology and Hepatology, Erasmus MC - University Medical Center, Rotterdam, The Netherlands. Electronic address: - - 2014
Chronic gastrointestinal ischemia (CGI) is more common than previously thought. Visible light spectroscopy (VLS) allows for non-invasive measurements of mucosal capillary hemoglobin oxygen saturation during endoscopy. We evaluated the response of patients with occlusive CGI to treatment following evaluation by radiologic imaging of the vasculature and VLS. We also identified ...
Yan Li-Rong LR aKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, State Key Laboratory of Cardiovascular Diseases bDepartment of Radiology cDepartment of Pathology and Physiology dDepartment of Echocardiography, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Midventricular obstructive hypertrophic cardiomyopathy (MVOHCM) is a rare form of hypertrophic cardiomyopathy. Knowledge regarding the diagnosis, morbidity and cardiovascular mortality is limited. In this study, we aimed to describe the long-term outcomes of patients with MVOHCM followed in a tertiary referral centre.Methods A retrospective study of 60 patients with MVOHCM ...
Casas Francisco F Unidad de Gestión Clínica de Neumología, Hospital Universitario San Cecilio, Granada, - - 2014
The effect of hereditary alpha-1 antitrypsin (AAT) deficiency can manifest clinically in the form of chronic obstructive pulmonary disease (COPD). AAT deficiency (AATD) is defined as a serum concentration lower than 35% of the expected mean value or 50mg/dl (determined by nephelometry). It is associated in over 95% of cases ...
Hoshina Takayuki T Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. Electronic address: - - 2014
The aim of this study is to investigate the utility of several biomarkers in differentiating bacterial community-acquired lower respiratory tract infection (CA-LRTI) from non-bacterial CA-LRTI in children and the difference of their diagnostic performance between pneumonia and bronchitis. A retrospective cohort study composed of 108 pediatric patients hospitalized for CA-LRTI ...
Koenekoop Robert K RK McGill Ocular Genetics Laboratory and Paediatric Ophthalmology, Montreal Children's Hospital, Departments of Paediatric Surgery, Human Genetics and Ophthalmology, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: - - 2014
Leber congenital amaurosis, caused by mutations in RPE65 and LRAT, is a severe form of inherited retinal degeneration leading to blindness. We aimed to assess replacement of the missing chromophore 11-cis retinal with oral QLT091001 (synthetic 9-cis-retinyl acetate) in these patients. In our open-label, prospective, phase 1b trial, we enrolled ...
Khanna Neena N Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, - - 2014
Gonadal involvement in males in lepromatous leprosy is not uncommon, but there is a paucity of literature on the involvement of gonads in female patients with leprosy. This study was undertaken to determine if there is any menstrual dysfunction, alteration in fertility status and circulating luteinizing hormone (LH), follicle-stimulating hormone ...
Schneider Birke B Medizinische Klinik II, Sana Kliniken Lübeck, Germany. Electronic address: - - 2014
This study evaluated the frequency, severity and outcome of complications in the clinical course of tako-tsubo cardiomyopathy (TTC). TTC is regarded as a benign disease since left ventricular (LV) function returns to normal within a short time. However, severe complications have been reported in selected patients. From 37 hospitals, 209 ...
Aytaç Bilal B Department of Biochemistry, Ministry of Health, Medical School of Ankara University, Ankara, Turkey, - - 2014
Migraine patients have an increased risk to develop deep white matter hyperintensities (WMH) than the general population. Oxidative stress is believed to play a role in the pathogenesis of migraine. The present study was undertaken to assess oxidant/antioxidant balance of migraineurs with and without WMH. We hypothesized that increased oxidative ...
Cabuk Gizem G Department of Cardiology, Turkey Yuksek Ihtisas Education and Research Hospital, Ankara, - - 2014
The sclerotic lesions of the aortic valve share common features with atherosclerosis. An anti-inflammatory protein, adiponectin, seems to have a protective effect on the cardiovascular system. The goal of our study is to determine adiponectin levels in patients with aortic sclerosis and to compare these values with the control group ...
Roldán V - - 2014
There are few biomarkers able to forecast new thrombotic events in patients with AF. In this framework, microRNAs have emerged as critical players in cardiovascular biology. In particular, miR-146a-5p is recognised as an important negative regulator of inflammation. This study aims to evaluate the prognostic role and biological effect of ...
Laterza Rosa Maria RM Department of General Gynecology and Gynecologic Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria, - - 2014
The aim of this study was to evaluate pelvic floor dysfunction and anatomical signs of pelvic organ prolapse (POP) in patients with levator ani muscle (LAM) trauma compared with patients with an intact LAM 1 year postpartum. In a prospective case-control study, primiparous women after vaginal delivery, with LAM trauma diagnosed ...
Marek Josef J Third Department of Medicine, First Medical Faculty, Charles University, U nemocnice 1, 128 02, Prague 2, Czech - - 2014
This paper presents our 18 years of experience in treating ACTH secreting adenomas (Cushing's disease and Nelson's syndrome) using the Leksell gamma knife (LGK) irradiation. Twenty-six patients with Cushing's disease were followed-up after LGK irradiation for 48-216 months (median 78 months). Seventeen patients had undergone previous surgery, in nine patients LGK irradiation was ...
Inal Salih S Department of Internal Medicine, Division of Nephrology, Süleyman Demirel University Medical School , Isparta , Turkey - - 2014
Abstract Introduction: Long-term exposure to dialysis solutions is an important contributor to the ongoing inflammatory process in peritoneal dialysis (PD) patients. Some studies have shown amelioration of this adverse effect with biocompatible solutions. We aimed to compare the neutrophil-to-lymphocyte (N/L) ratio in PD patients using biocompatible and standard solutions and ...
Roulin Marie-José MJ Institute of Higher Education and Nursing Research, Lausanne University-CHUV, 1010 Lausanne, Switzerland, - - 2014
The primary objective of this study was to describe the frequency of behaviors observed during rest, a non-nociceptive procedure, and a nociceptive procedure in brain-injured intensive care unit (ICU) patients with different levels of consciousness (LOC). Second, it examined the inter-rater reliability and discriminant and concurrent validity of the behavioral ...
Otsuka Kenichiro K Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, - - 2014
Arterial stiffness is a significant predictor of cardiovascular disease (CVD), the risk of which is modified by medications for atherosclerotic risk factors and life-style changes. Cardio-ankle vascular index (CAVI) provides noninvasive, objective information on arterial stiffness, independent of blood pressure. This study aimed to investigate changes in CAVI after management ...
Arends Pauline P Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The - - 2014
Hepatocellular carcinoma (HCC) risk-scores may predict HCC in Asian entecavir (ETV)-treated patients. We aimed to study risk factors and performance of risk scores during ETV treatment in an ethnically diverse Western population. We studied all HBV monoinfected patients treated with ETV from 11 European referral centres within the VIRGIL Network. ...
Lou M M From the Departments of Neurology (M.L., Z.C., J.W., H.H., X.C., Z.S.) and Radiology (J.S.), the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China. hzzjsjz@163.com - - 2014
Asymmetric hypointensity of cerebral veins on susceptibility-weighted imaging has been shown to indirectly reflect tissue hypoxia after cerebral ischemia. We therefore investigated whether patients with prominent asymmetry of the cerebral veins on SWI and a relatively small diffusion-weighted imaging lesion (SWI-DWI mismatch), representing the presence of salvageable tissue, were more ...
McNicholl Adrian G AG aHospital of La Princesa, and Instituto de Investigación Sanitaria Princesa bCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain Gastroenterology Units of cHospital Mutua de Terrassa, Terrassa dHospital del Mar, Barcelona eHospital Rio Hortega, Valladolid fHospital de Cabueñes, Gijon gHospital Costa del Sol, Malaga hHospital San Jorge, Huesca iHospital Clínico de Zaragoza, Zaragoza jHospital Virgen de la Salud, - - 2014
It has been suggested that GastroPanel might be a useful tool for the diagnosis of chronic atrophic gastritis (CAG) measuring four biomarkers in blood: basal gastrin-17 (G17), pepsinogen I and II (PGI and PGII), and Helicobacter pylori antibodies. To determine the accuracy of GastroPanel for the diagnosis of CAG. This ...
Sildiroglu Onur O *Department of Radiology, University of Virginia, Charlottesville, VA †Radiology, Gulhane Medical School, Istanbul, Turkey ‡Department of Interventional Radiology, Rush University Medical Center, Chicago, - - 2014
To report the outcomes following catheter angiography with or without embolization in patients with acute upper gastrointestinal nonvariceal hemorrhage (UGINH). A review of electronic medical records was performed to identify all potential patients for this study between 2001 and 2011. Patients with first-time UGINH who required angiographic localization and endovascular ...
Baturova Maria A MA Department of Cardiology, Clinical Sciences, Lund University, SE-221 85 Lund, Sweden Research, Clinical and Educational Center 'Cardiology', St. Petersburg State University, St. Petersburg, Russia - - 2014
Data from national discharge registers are commonly used to estimate prevalence and incidence of atrial fibrillation (AF) in epidemiology studies. However, sensitivity and specificity of register-based AF diagnosis have not been evaluated. We sought to assess the validity of AF diagnosis in the Swedish Patient Register against electrocardiography (ECG) documentation ...
Kulke Matthew H MH M Kulke, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 02115, United States - - 2014
Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. In this prospective, randomized study, patients with evidence of carcinoid ...
Honda Hirokazu H Division of Nephrology, Department of Medicine, Showa University Koto Toyosu Hospital, Tokyo, Japan. Electronic address: - - 2014
Inflammation contributes to hemopoiesis by lowering responses to epoetin (EPO) and to an increase in the mortality of patients on hemodialysis. However, nutritional status might alter associations among inflammation, EPO responsiveness, and the risk of mortality. We assessed the effect of inflammation on mortality according to nutritional status among EPO ...
Chan Maria M Department of Nutrition and Dietetics, St. George Hospital, Sydney, New South Wales, Australia; Illawarra Health and Medical Research Institute, School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia; St. George Clinical School, School of Medicine, University of New South Wales, Sydney, Australia. Electronic address: - - 2014
To describe the baseline nutritional characteristics of a cohort of end-stage kidney disease (ESKD) patients attending a pre-dialysis clinic. Outpatient clinic of a metropolitan tertiary teaching hospital in Sydney, Australia. All ESKD patients attending the multidisciplinary pre-dialysis assessment clinic between April 2002 and March 2008. Retrospective analysis of data extracted from ...
Jochheim D D Cardiology Department, Munich University Clinic, Germany. Electronic address: - - 2014
To identify independent predictors of contrast medium-induced acute kidney injury (CI-AKI) after enhanced multidetector-row computed tomography (MDCT) prior to transcatheter aortic valve implantation (TAVI) in high-risk patients. The present single-centre study analysed retrospectively 361 patients who were assessed using MDCT prior to TAVI. CI-AKI was defined as an increase in ...
Liu Xi X Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an, - - 2014
Alterations in the cerebral circulation time (CCT) are observed in several cerebrovascular diseases. We designed a new method of global CCT measurement using gray-scale contrast-enhanced ultrasound and studied healthy Chinese adults and patients with intracranial shunts. Eighty-one healthy volunteers and eight patients with intracranial shunt disease were enrolled. The contrast ...
Ni Zhaohui - - 2014
Primary IgA nephropathy (IgAN) is the most common form of idiopathic glomerulonephritis worldwide. Although most patients are able to achieve remission with the current therapy, a large number of patients will still progress to end-stage renal disease. This study aimed to evaluate kidney disease progression and the risk factors for ...
Frasca D D Department of Anaesthesia and Intensive Care, University Hospital of Poitiers, Poitiers, - - 2014
Respiratory depression, a potentially serious complication after general anaesthesia, can be detected promptly by close monitoring of both oxygen saturation and respiratory rate. Obese patients have morphological changes that may impair the reliability of monitoring devices. In this study, respiration rate was simultaneously recorded every second for up to 60 min ...
Gouda Zaghloul Z Nephrology Department, Damanhur Medical National Institute, General Organization of Teaching Hospitals and Institutes, Damanhur - - - 2014
Venous catheters provide access for hemodialysis (HD) when patients do not have functioning access device. Obstruction of jugular, femoral or even external iliac vessels further depletes options. Subclavian approach is prohibited. Catheterization of inferior vena cava requires specialized equipment and skills. The purpose is to assess a new lifesaving HD ...
Kuroda Hidekatsu H Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, 020-8505, - - 2014
We measured liver stiffness (LS) in patients with acute liver failure (ALF) using acoustic radiation force impulse (ARFI) elastography and investigated the usefulness of measuring LS for predicting the prognosis of ALF patients. From April 2010 to December 2013, we evaluated 63 patients with acute liver disease. The subjects included ...
Noppe G G Department of Paediatrics, Division of Endocrinology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, the - - 2014
Glucocorticoid replacement therapy in patients with adrenal insufficiency needs to be tailored to the individual patient based on body composition and clinical signs and symptoms as no objective method for assessment of treatment adequacy is available. Current treatment regimens are often not satisfactory, which is shown by the adverse metabolic ...
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