Search Results
Results 701 - 750 of 17183
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Toyama T T Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, - - 2014
PurposeTo evaluate the possible causative role of central serous chorioretinopathy (CSC) in the development of exudative age-related macular degeneration (AMD).MethodsIn a cross-sectional study at an institutional setting, 150 control subjects who had senile cataract or nasolacrimal duct stenosis and who were older than 50 years were enrolled. The background data ...
Ladep Nimzing G NG Department of Medicine, Imperial College London, St Mary's Campus, South Wharf Road, London, W2 1NY, United - - 2014
There is no clinically applicable biomarker for surveillance of hepatocellular carcinoma (HCC), as the sensitivity of serum α-fetoprotein (AFP), is too low for this purpose. Here, we determined the diagnostic performance of a panel of urinary metabolites of HCC patients from West Africa. Urine samples were collected from Nigerian and ...
Chernyshov P V PV Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine - - - 2014
Atopic dermatitis (AD) and psoriasis have significant negative impact on patients' lives. To compare the impact of psoriasis and AD in adult patients matched by disease severity and to perform further validation of the Ukrainian versions of the DLQI and Skindex-16 in these skin conditions. 63 adult AD and 63 ...
Domer Amanda S AS Department of Communication Sciences & Disorders, University of South Florida, Tampa, - - 2014
To evaluate pharyngeal strength and upper esophageal sphincter opening in patients with unilateral vocal fold immobility (UVFI). Case control study. Charts of individuals with UVFI who underwent a videofluoroscopic swallow study were reviewed. To exclude confounding variables associated with pharyngeal weakness, inclusion was limited to patients with iatrogenic and idiopathic ...
Min Byung-Hoon BH Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
There have been few population-based studies on the prevalences of gastroesophageal reflux disease (GERD) and dyspepsia using Rome III criteria in Asian countries. A population-based, cross-sectional study was conducted by telephone interviews of 5,000 Koreans between the ages of 20-69 years. Gastrointestinal symptoms were assessed by a translated Korean version of ...
Gulsahi Ayse A Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Baskent University, Ankara, - - 2014
To analyze specific volatile sulfur compound(VSC) levels in a group of chronic renal failure(CRF) patients and determine the relationship between these VSC levels and organoleptic measurements, blood urea nitrogen(BUN) levels, dental and periodontal conditions, salivary flow rate,and tongue coating scores. One examiner performed organoleptic and VSC measurements on fifty-patients with ...
Lee Cheng-Chia CC Department of Neurological Surgery, University of Virginia, Charlottesville, VA, - - 2014
The subtypes of somatotroph-cell pituitary adenomas have been correlated with clinical and histopathological variables. Densely granulated somatotroph-cell (DG) adenomas are typically highly responsive to somatostatin analog drugs, whereas sparsely granulated somatotroph-cell (SG) are less responsive. The aim of the study is to determine the effect of stereotactic radiosurgery (SRS) on ...
Khan Muhammad Shahzeb MS Dow University of Health Sciences, 109/2 Khayabane Amir Khusro Phase 6 DHA, Karachi, Pakistan, - - 2014
Previous studies in the western world have reported the possible association of obstructive sleep apnea (OSA) with anxiety and cardiovascular diseases. However, the data from developing countries such as Pakistan remains scarce in this regard. The main aim of this study was to investigate the prevalence of coronary artery disease ...
Tokushige Katsutoshi K Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University, Tokyo, - - 2014
To clarify the clinical features of patients with hepatocellular carcinoma (HCC) with cryptogenic liver diseases, we analyzed the data from a nationwide survey in Japan. The survey was conducted in 2009. The factors examined included age and underlying liver diseases: alcoholic liver disease (ALD; n=991), nonalcoholic fatty liver disease (NAFLD; ...
Janols Helena H Departments of Infectious Diseases, Surgery, and Medical Microbiology, Center for Molecular Pathology, and Cytometry Laboratory and Department of Laboratory Medicine, Skane University Hospital, and Department of Laboratory Medicine, Translational Cancer Research, Medicon Village, Lund University, Malmo, Sweden; andDepartments of Infectious Diseases, Surgery, and Medical Microbiology, Center for Molecular Pathology, and Cytometry Laboratory and Department of Laboratory Medicine, Skane University Hospital, and Department of Laboratory Medicine, Translational Cancer Research, Medicon Village, Lund University, Malmo, Sweden; - - 2014
The causative microorganisms dictate the type of MDSC generated in sepsis patients, and a large proportion of PMN-MDSCs in gram-positive sepsis includes immunosuppressive myeloid blasts. MDSCs constitute a heterogeneous population of immature myeloid cells that potently suppress immune responses. They were identified originally in cancer patients and have since been ...
Ikesue Hiroaki H Department of Pharmacy, Kyushu University Hospital, Fukuoka, Japan - - 2014
Severe hypocalcemia sometimes develops during denosumab treatment for bone metastases from cancer and is, therefore, an important issue. However, limited information is available on the risk factors for hypocalcemia and the appropriate interval for monitoring serum calcium concentration. The present study aimed to identify the risk factors for grade ≥2 ...
Jankowska Ewa A EA Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wrocław Medical University, Wrocław, Poland Cardiology Department, Centre for Heart Diseases, Military Hospital, ul. Weigla 5, Wrocław 50-981, Poland - - 2014
Acute heart failure (AHF) critically deranges haemodynamic and metabolic homoeostasis. Iron is a key micronutrient for homoeostasis maintenance. We hypothesized that iron deficiency (ID) defined as depleted iron stores accompanied by unmet cellular iron requirements would in this setting predict the poor outcome. Among 165 AHF patients (age 65 ± ...
Zis Panagiotis P National Parkinson Foundation International Centre of Excellence, King's College Hospital NHS Foundation Trust, London, - - 2014
Background: Recent studies have demonstrated that, contrary to common perception non-motor symptoms (NMS) occur and may dominate early and untreated stage of Parkinson's disease (PD). Objective: The aim of this ongoing study was to describe the overall NMS profile and burden in drug naïve PD patients (DNPD) compared to a ...
Nguyen Huong H Rheumatology Department, Purpan Hospital, UMR 1027 Inserm, UMR 1027, Université Paul Sabatier Toulouse 3, Toulouse, Rheumatology Department, Pitie Salpetriere Hospital, Paris and UMR 1043, Inserm, CPTP Toulouse Purpan, Toulouse, - - 2014
The aims of this study were to assess the prevalence of US-detected residual synovitis in patients with RA in clinical remission (CR) and evaluate its predictive value for relapse and structural progression. We performed a systematic literature search of Medline, Embase and rheumatology meeting databases from 1 January 2001 to ...
Lazzeri Chiara C Intensive Cardiac Coronary Unit, Heart and Vessel Department, Azienda, Ospedaliero-Universitaria Careggi, Florence, - - 2014
We aimed at assessing the impact of increased HbA1c (≥6.5%) on 1-year mortality in consecutive patients with ST Elevation Myocardial Infarction (STEMI) submitted to primary percutaneous coronary intervention (PCI). The study population comprises 1205 STEMI patients treated with primary PCI and consecutively admitted to our Center from 1 January 2004 ...
Hurks Rob R Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands; Experimental Cardiology, University Medical Center Utrecht, Utrecht, The - - 2014
Evidence is emerging that abdominal aortic aneurysm (AAA) formation cannot completely be explained by systemic atherosclerosis and is in part due to other pathophysiological mechanisms such as local immune reactions. The aim of the present study was to study variance in AAA wall inflammation, and relate that to clinical patient ...
Sugita Shurei - - 2014
The aim of this study was to examine the clinical characteristics of rheumatoid arthritis (RA) patients who underwent cervical spine surgery using a multicenter observational database. We obtained data from a nationwide observational cohort database of patients with rheumatic diseases (National Database of Rheumatic Diseases by iR-net in Japan (NinJa)) ...
Van der Aa Frank F Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, - - 2014
To investigate the role of urinary BK polyoma virus (BKPyV) in the pathophysiology and prognosis of patients with painful bladder syndrome/interstitial cystitis (PBS/IC). Urine samples were collected from 15 patients with PBS/IC and 8 control patients (with urolithiasis, overactive bladder and benign prostatic hyperplasia). BKPyV titres were quantitatively determined using ...
Takahara Tadamori T Department of Pediatrics, Hyogo Prefectural Tsukaguchi Hospital, Amagasaki, - - 2014
Clinical features and laboratory parameters in patients with incomplete Kawasaki disease (KD) and systemic juvenile idiopathic arthritis (s-JIA) tend to overlap. Furthermore, there have been no definite biomarkers for these diseases. This situation makes the clinical diagnosis of these patients difficult. In this study, we aimed to measure serum interleukin ...
Eperon Simone S Ocular Immunology, Jules Gonin Eye Hospital, University of Lausanne, 15, Av. de France, 1000, Lausanne 7, Switzerland, - - 2014
To prospectively investigate patients with seasonal allergic conjunctivitis (SAC) during the pollen season and test associations between tears total IgE, eotaxin concentrations, and SAC severity. Enrolled patients presented ocular symptoms and clinical signs of SAC at the time of presentation. Ocular itching, hyperaemia, chemosis, eyelid swelling, and tearing were scored, ...
Haruki Shintaro S Department of Cardiology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, - - 2014
It remains unclear whether flecainide, a Class I antiarrhythmic drug, improves left ventricular pressure gradient (LVPG) or symptoms in patients with obstructive hypertrophic cardiomyopathy (HCM). Our study evaluated the long-term efficacy of flecainide, compared to disopyramide, when administered orally, on LVPG and symptoms in obstructive HCM patients. Among 164 obstructive ...
Sundin Johanna J School of Health and Medical Sciences, Örebro University , Örebro , - - 2014
Abstract Background. Irritable bowel syndrome (IBS) is characterized by chronic abdominal symptoms such as pain, discomfort, and altered bowel habits. A subset of IBS patients, denoted as post-infectious IBS (PI-IBS) patients, develop symptoms after an enteric infection. Distinct abnormalities in the gut mucosa, including mucosal inflammation, have been proposed to ...
Liu W W Center for Kidney Disease, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, - - 2014
Management of hypertension is one of the fundamental interventions in dialysis patients. However, the profile of interdialytic blood pressure (BP) in Chinese dialysis patients remains elusive. We aim to investigate this issue as well as the effect of antihypertensive medication in this population. We performed 44-h ambulatory BP in 90 ...
Kusano Motoyasu M Department of Gastroenterology, Gunma University Hospital, Maebashi, Gunma, Japan, - - 2014
During maintenance proton pump inhibitor (PPI) therapy, patients with gastroesophageal reflux disease (GERD) sometimes complain of upper gastrointestinal symptoms. To evaluate upper gastrointestinal symptoms in patients on maintenance PPI therapy for erosive GERD or non-erosive reflux disease (NERD) without endoscopic mucosal breaks by using a new questionnaire. At Gunma University ...
Kushchayeva Yevgeniya Y Medstar Washington Hospital Center, Department of Internal Medicine , 110 Irving St NW , Washington, District of Columbia, United States, 20010 , 301-466094-84 ; - - 2014
Spinal metastases (SMs) due to thyroid cancer (TC) are associated with significantly reduced quality of life. The goal of this study is to analyze the clinical manifestations, presentation, and treatments of TC-SMs, describe specific features of SMs associated with different TC types. A retrospective analysis of 202 TC-SM patients treated ...
Morris Michael J MJ San Antonio Military Medical Center, Pulmonary/Critical Care , 3551 Roger Brooke Drive , Fort Sam Houston, Texas, United States, 78234 , 210-916-3027 , 210-916-4721 ; - - 2014
Rationale: Due to increased levels of airborne particulate matter in Southwest Asia, deployed military personnel are at risk for developing acute and chronic lung diseases. Increased respiratory symptoms are reported, but limited data exists on reported lung diseases. Objective: To evaluate new respiratory complaints in military personnel returning from Southwest ...
Yabushita Hiroto H Department of Cardiology, Interventional Cardiology Unit, New Tokyo - - 2014
Background:There is little data on percutaneous coronary intervention (PCI) using rotational atherectomy (Rota) for severely calcified unprotected left main (ULM) lesions.Methods and Results:Between January 2005 and August 2011, 64 consecutive patients who underwent drug-eluting stent implantation using Rota were retrospectively evaluated. Of these, 54.7% and 20.3% patients had diabetes and were undergoing ...
Ariza-Solé Albert A Cardiology Department, Bellvitge University Hospital, Spain - - 2014
A better prognosis in obese patients has been described in acute coronary syndromes (ACS). However, this evidence is mostly based on retrospective studies and has provided conflicting results. No study reported cause-specific mortality according to body mass index (BMI) in ACS. We aimed to prospectively assess the impact of BMI ...
Meng Qingxi Q Department of Spinal Cord Injury, Institute of Orthopedics and Traumatology of Chinese PLA, General Hospital of Jinan Military Area Command, Jinan, Shandong, - - 2014
We explored the effect of adjunctive acupuncture on secondary osteoporosis in patients with spinal cord injury (SCI). Patients with subacute SCI were recruited and divided into two groups by patient choice: group 1 patients received standard combination therapy and group 2 patients received combination therapy plus acupuncture for 3 months. The ...
Amarenco Pierre P Department of Neurology and Stroke Center, Bichat University Hospital, Paris, France; INSERM U-698 and Paris-Diderot University, Paris, - - 2014
We aimed to stratify the risk of vascular event recurrence in patients with cerebral infarction according to living and socioeconomic characteristics and geographic region. The Outcomes in Patients with TIA and Cerebrovascular Disease (OPTIC) study is an international prospective study of patients aged 45 years or older who required secondary ...
Tao Jeremiah P JP *Gavin Herbert Eye Institute, University of California-Irvine, Irvine, California, U.S.A.; and †University of Louisville, Louisville, Kentucky, - - 2014
To evaluate the efficacy of a lateral tarsoconjunctival flap suspension procedure to improve paralytic eyelid malposition. Retrospective chart review (with photograph and videographic data) of consecutive patients between 2008 and 2013 with permanent unilateral paralytic eyelid malposition treated with a far lateral tarsoconjunctival flap lower eyelid suspension alone or in ...
Weijenborg Pim W PW Academic Medical - - 2014
Background and aim: Increased esophageal sensitivity and impaired mucosal integrity have both been described in gastroesophageal reflux disease (GERD) patients, but their relationship is unclear. Aim of this study was to investigate acid sensitivity in patients with erosive and non-erosive reflux disease and controls, to determine the relation with functional ...
Chung Sharon A SA Division of Rheumatology, Rosalind Russell-Ephraim P. Engleman Medical Research Center for Arthritis, University of California, San Francisco, - - 2014
Lupus nephritis is a manifestation of SLE resulting from glomerular immune complex deposition and inflammation. Lupus nephritis demonstrates familial aggregation and accounts for significant morbidity and mortality. We completed a meta-analysis of three genome-wide association studies of SLE to identify lupus nephritis-predisposing loci. Through genotyping and imputation, >1.6 million markers ...
Chinsongkram Butsara B B. Chinsongkram, MS, Division of Physical Therapy, Faculty of Health Science, Srinakharinwirot University, Nakhon Nayok, Thailand, and Faculty of Physical Therapy, Rangsit University, Pathum Thani, - - 2014
The Balance Evaluation Systems Test (BESTest) is new clinical balance assessment tool but it has never been validated in patients with subacute stroke. To examine the reliability and validity of the BESTest in patients with subacute stroke. An observational reliability and validity study. Twelve patients participated in the interrater and ...
Friedlander Justin I JI Department of Urology, UT Southwestern Medical Center, Dallas, TX; The Arthur Smith Institute for Urology, Hofstra North Shore-LIJ School of Medicine at Hofstra University, New Hyde Park, NY. Electronic address: - - 2014
To compare the metabolic profile of patients who form mixed calcium oxalate (CaOx)/uric acid (UA) stones to those of pure CaOx and pure UA stone formers. We performed a retrospective review of 232 patients, with both stone composition analysis and 24-hour urine collection, seen between March 2002 and April 2012. ...
Nagar Sapna S Endocrine Surgery Research Program, Department of Surgery, Pritzker School of Medicine, University of Chicago, Chicago, IL. Electronic address: - - 2014
Minimally invasive parathyroidectomy is successful in achieving cure for most patients with primary hyperparathyroidism. Most surgeons rely on preoperative imaging as part of the workup for localization. Ultrasonography and sestamibi are the 2 most commonly used preoperative imaging studies. When these 2 studies are positive and concordant the preoperative localization ...
Villanacci Vincenzo V Pathology Section, Department of Molecular and Translational Medicine, Spedali Civili and University of Brescia, - - 2014
Although it is usually not difficult to diagnose inflammatory bowel disease (IBD) on surgical resection specimens, difficulties sometimes arise in differentiating these entities from other forms of colitis on endoscopic biopsy specimens. Basal plasmacytosis is considered as an early feature of IBD colitis, but it is rare in non-IBD colitides. ...
Guelsin Gláucia A S GA Hemocentro-UNICAMP, Campinas State University, Campinas, Sao Paulo, - - 2014
Matching for Rh and K antigens has been used in an attempt to reduce antibody formation in patients receiving chronic transfusions but an extended phenotype matching including Fy(a) and Jk(a) antigens has also been recommended. The aim of this study was to identify an efficient transfusion protocol of genotype matching ...
Vancampfort Davy D University Psychiatric Centre KU Leuven, KU Leuven Department of Neurosciences, Leuvensesteenweg 517, B-3070 Kortenberg, Belgium; KU Leuven Department of Rehabilitation Sciences, Tervuursevest 101, B-3001 Leuven, Belgium. Electronic address: - - 2014
This pilot study aimed to explore relationships between metabolic and lung functions in patients with schizophrenia. Eighty patients with schizophrenia (55♂; 36.8±10.0 years) underwent a spirometry, were screened for metabolic syndrome (MetS), performed a 6-min walk test (6MWT), and completed the International Physical Activity Questionnaire and the Psychosis evaluation tool ...
Arellano Martha L ML Department of Hematology and Oncology, Emory University School of Medicine, Atlanta, GA. Electronic address: - - 2014
Obatoclax mesylate is a small-molecule Bcl-2 homology domain-3 mimetic that neutralizes antiapoptotic Bcl-2-related proteins. We evaluated obatoclax in untreated MDS patients with anemia/thrombocytopenia. Twenty-four patients with a bone marrow blast count of ≤ 10% and anemia (hemoglobin level < 10 g/dL) or thrombocytopenia (platelet count < 50 × 10(9)/L) were eligible to receive intravenous ...
Poredoš P P Department of Vascular Disease, University Clinical Centre Ljubljana, Slovenia - - - 2014
Peripheral arterial disease (PAD) is one of the most frequent manifestations of atherosclerosis and is associated with atherosclerosis in the coronary and carotid arteries, leading to a highly increased incidence of cardiovascular events. Major risk factors of PAD are similar to those that lead to atherosclerosis in other vascular beds. ...
Ribeiro Erlane Marques - - 2014
Purpose :  This study aimed to describe the orofacial features of 26 unrelated Brazilian patients with mucopolysaccharidosis and to verify any possible associations between these findings and specific types of mucopolysaccharidosis. Methods :  Patients were diagnosed with mucopolysaccharidosis and systemically evaluated. Following consent, a clinical assessment form was completed. Facial ...
Krbot Skoric Magdalena M Department of Neurology, University Hospital Center Zagreb, Kišpatićeva 12, 10000, Zagreb, - - 2014
The aim of the present study was to evaluate vestibular nerve involvement in patients with Bell's palsy with ocular and cervical vestibular evoked myogenic potentials (oVEMP and cVEMP). Ten patients who were diagnosed with Bell's palsy and ten healthy controls were included. All patients underwent VEMP recordings within 6 days after ...
Menon Bijoy K BK Departments of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada Departments of Radiology, University of Calgary, Calgary, Alberta, Canada Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, - - 2014
To determine the diagnostic yield of echocardiography and its utility in changing medical management; and to derive a risk score to guide its use in patients with in-hospital stroke or transient ischaemic attack (TIA). We carried out a retrospective chart review from January 2009 to June 2010 of patients with ...
Tyrakowski Marcin M Department of Orthopedics, Pediatric Orthopedics and Traumatology, The Centre of Postgraduate Medical Education in Warsaw, Konarskiego 13; 05-400 Otwock, Poland (Dr Tyrakowski); Department of Orthopedic Surgery, University of Illinois at Chicago, 835 South Wolcott Ave; Room E-270, Chicago, Illinois, 60612, United States (Drs Tyrakowski and Siemionow); Illinois Bone and Joint Institute, 9000 Waukegan Road, Morton Grove, IL 60053, United States (Dr - - 2014
Study Design. Retrospective radiographic analysis of sagittal spinopelvic parameters in skeletally mature patients with Scheuermann's disease (SD).Objective. To analyze anatomical and positional parameters of spinopelvic sagittal alignment in mature patients with SD.Summary of Background Data. Sagittal spinopelvic alignment has already been characterized in normal subjects and deviations in sagittal parameters ...
Frazee Erin N EN Department of Pharmacy, Mayo Clinic, Rochester, - - 2014
Background: Hypertriglyceridemia has been associated with adverse outcomes in patients receiving intravenous fat emulsions (IVFEs), but little is known about its prevalence and causes. Materials and Methods: The study investigated whether a relationship exists between body mass index (BMI) and triglyceride tolerance in parenterally fed patients. We conducted a retrospective ...
Cúrdia Gonçalves Tiago T aGastroenterology Department, Centro Hospitalar do Alto Ave, Guimarães bLife and Health Sciences Research Institute, University of Minho, Braga/Guimarães, cICVS/3B's, PT Government Associate Laboratory, Braga/Guimarães, - - 2014
Small bowel capsule endoscopy (SBCE) is currently a fundamental tool in the etiological study of obscure gastrointestinal bleeding (OGIB). However, the impact of a negative exam and the risk of rebleeding are not entirely known. The aim of this study was to evaluate the outcomes of patients with OGIB and ...
Ludidi S S Division Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism - Maastricht University Medical Center+, Maastricht, The - - 2014
Irritable bowel syndrome (IBS) is a heterogenous disorder with visceral hypersensitivity as important hallmark. It is not known whether IBS patients with visceral hypersensitivity have different epidemiological and clinical characteristics compared with IBS patients without visceral hypersensitivity. Aim of our study was to compare in detail a large group of ...
Sakamoto Naoya N Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Tokyo, - - 2014
Distinguishing life-threatening toxoplasmic encephalitis (TE) from brain lymphoma in patients with acquired immunodeficiency syndrome (AIDS) may be difficult. Empiric anti-toxoplasmosis treatment is often initiated because of the reluctance in performing brain biopsies, which may delay the diagnosis and treatment of brain lymphoma in Japan. In this study, we retrospectively examined ...
Corsa Amoreena C AC Department of Research & Development, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, USA. Electronic address: - - 2014
& Aims: A recent study compared the efficacy of tenofovir disoproxil fumarate (TDF) vs the combination of emtricitabine and TDF (FTC/TDF) in patients with lamivudine-resistant (LAM-R) chronic hepatitis B, treated for as long as 96 weeks. We report findings from resistance analyses conducted for this study. Two hundred eighty patients ...
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