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Results 701 - 750 of 14713
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Vegesna Anil K AK Department of Medicine (Gastroenterology), The Feinstein Institute for Medical Research, Hofstra North Shore-LIJ School of Medicine, 350 Community Drive, Manhasset, NY, 11030, USA, - - 2014
Little is known about the role of muscularis mucosa at the gastroesophageal junction (GEJ). To evaluate the movement of the mucosa/muscularis-mucosa/submucosa (MMS) at the GEJ in normal subjects and in patients with gastroesophageal reflux disease (GERD). Gastroesophageal junctions of 20 non-GERD subjects and 10 patients with GERD were evaluated during ...
Long Youming Y Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and The Ministry of Education of China, Institute of Neuroscience and The Second Affiliated Hospital of GuangZhou Medical University, and Department of Neurology, The Second Affiliated Hospital of GuangZhou Medical University, GuangZhou, PR - - 2014
Objective: We assessed the clinical significance of antineutrophil cytoplasm antibodies (ANCA) in patients with idiopathic inflammatory-demyelinating disease (IIDD). Methods: A consecutive cohort of 269 subjects with IIDD and 595 controls was analyzed retrospectively. Results: Among all subjects, ANCA positivity rates were low [9.5% in a perinuclear pattern (pANCA) and 2.3% ...
Tak Hyung Jun - - 2014
The role of the arcuate fasciculus (AF) in the dominant hemisphere in stroke patients with aphasia has not been clearly elucidated. We investigated the relation between language function and diffusion tensor tractography(DTT) findings for the left AF in chronic stroke patients with aphasia. Twenty five consecutive right-handed stroke patients with ...
Pal Gian G Department of Neurology, Medstar Washington Hospital Center, 110 Irving Street N.W., Washington, DC, 20010, USA, - - 2014
In 1949, asterixis was first described in patients with hepatic encephalopathy. It was quickly recognized that this phenomenon also occurs in other generalized encephalopathies and sometimes results from structural brain lesions. This paper is a study of asterixis in the general neurology clinic and on the inpatient neurology consultation service. ...
Zheng Su-Jun SJ Su-Jun Zheng, Shuang Liu, Mei Liu, Jun-Feng Li, Feng Ren, Yu Chen, Zhong-Ping Duan, Artificial Liver Center, Beijing Youan Hospital, Capital Medical University, Beijing 100069, - - 2014
To determine the prognostic value of circulating indicators of cell death in acute-on-chronic liver failure (ACLF) patients with chronic hepatitis B virus (HBV) infection as the single etiology. Full length and caspase cleaved cytokeratin 18 (detected as M65 and M30 antigens) represent circulating indicators of necrosis and apoptosis. M65 and ...
El-Salhy Magdy M Magdy El-Salhy, Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, 54 09 Stord, - - 2014
To study the ileal endocrine cell types in irritable bowel syndrome (IBS) patients. Ninety-eight patients with IBS (77 females and 21 males; mean age 35 years, range 18-66 years) were included, of which 35 patients had diarrhea (IBS-D), 31 patients had a mixture of both diarrhea and constipation (IBS-M), and ...
Dumitrescu Gabriela G Gabriela Dumitrescu, Catalina Mihai, Mihaela Dranga, Cristina Cijevschi Prelipcean, Department of Medical Sciences, Grigore T. Popa University of Medicine and Pharmacy, Iasi 700115, - - 2014
To describe the relationship between vitamin D levels and inflammatory bowel disease (IBD) characteristics in northeastern Romanian patients. This was a prospective study of 47 consecutive IBD patients admitted to The Institute of Gastroenterology and Hepatology in Iasi, Romania between March 2011 and June 2012. The diagnosis of IBD was ...
Yildiz Abdulmelik A aDepartment of Cardiology, Medical Park Hospital bDepartment of Cardiology, School of Medicine, Istanbul Medipol University, Istanbul cDepartment of Cardiology, School of Medicine, Kafkas University, Kars, - - 2014
It has been shown that increased red blood cell distribution width (RDW) predicts adverse outcomes in cardiovascular disease and in patients undergoing a percutaneous coronary intervention. The aim of the present study was to assess the predictive value of preinterventional RDW on the development of in-stent restenosis (ISR) in patients ...
Ciprandi G - - 2014
Allergic rhinitis (AR) is characterized by Th2 polarized immune response. Soluble HLA (sHLA) molecules play an immunomodulatory activity. Two different studies evidenced that both patients with seasonal AR (SAR) and patients with perennial AR (PAR) had higher sHLA-G levels than normal controls. The aim of this study was to compare ...
Assanasen P - - 2014
Radiofrequency inferior turbinate reduction (RFITR) of inferior turbinate hypertrophy (ITH) is an effective way to treat patients with intractable nasal mucosal obstruction. The objective of this study was to assess smell ability, nasal symptoms, inferior turbinate grading (ITG), peak nasal inspiratory flow (PNIF) of patients with chronic rhinitis (CR), and ...
Goyale Atul A Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, Denmark Hill, London, - - 2014
Refeeding syndrome (RS) is a potentially fatal condition that can occur following the re-introduction of nutrition after a period of starvation. Hypophosphataemia following the reintroduction of nutrition is often the only reliable biochemical marker of RS. Refeeding index (RI) generated from baseline insulin-like growth factor-1 (IGF-1) and leptin has been ...
Moreno Nadia N Servicios de Medicina Digestiva y Radiodiagnóstico, Hospital Universitario Dr. Peset. Valencia, Universidad de Valencia, Spain. Electronic address: - - 2014
The objective of this study was to analyze the accuracy of abdominal ultrasonography (AUS) in the assessment of mucosal healing in patients with Crohn's disease (CD) receiving immunomodulators and/or biological treatment, with ileocolonoscopy as the reference standard. Thirty patients were included in a prospective longitudinal study. All patients underwent ileocolonoscopy ...
Hardy Thomas G TG Royal Victorian Eye and Ear Hospital, Melbourne, - - 2014
To describe the clinical, histopathologic, and radiologic features of a recently identified cause for enlargement of the infraorbital canal. Retrospective, noncomparative case series. Consecutive patients were identified from the orbital databases at Moorfields Eye Hospital, London, England, and the Royal Victorian Eye and Ear Hospital, Melbourne, Australia. A retrospective, noncomparative ...
Kim Tae-Jong TJ Department of Rheumatology, Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju, Department of Radiology and Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of - - 2014
Objectives. The aim of this study was to determine whether the presence of peripheral arthritis can affect radiographic structural damage in patients with AS.Methods. A total of 915 subjects comprising 363 patients with a history of peripheral arthritis and 552 patients without a history of peripheral arthritis obtained from the ...
Weingaertner Vera V Department of Palliative Medicine, Clinical Trials Unit (BMBF 01KN1106), and Centre for Integrated Oncology - - 2014
Breathlessness is a distressing symptom in advanced disease. Understanding its patterns, burden and palliative care (PC) needs over time is important to improve patients` quality of life. To describe and compare the courses of refractory breathlessness, functional status, distress and PC needs in patients with advanced chronic obstructive pulmonary disease ...
Sheth Sameer A SA Department of Neurosurgery, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York, - - 2014
To determine the ability of foramen ovale electrodes (FOEs) to localize epileptogenic foci after inconclusive noninvasive investigations in patients with suspected mesial temporal lobe epilepsy (MTLE). We identified patients with medically intractable epilepsy who had undergone FOE investigation for initial invasive monitoring at our institution between 2005 and 2012. Indications ...
Tan X X Department of Ophthalmology, Wuxi No. 2, People's Hospital, Nanjing Medical University, Wuxi, - - 2014
PurposeTo determine the levels of Th17-associated cytokines, particularly interleukin (IL)-17 and IL-22 in tears of patients with dry eye syndrome.MethodsTear samples were collected from 20 healthy volunteers, 20 dry eye (DE) patients with non-Sjögren's syndrome (NSSDE) and 20 DE patients with Sjögren's syndrome (SSDE). Symptom questionnaire was self-administered and multiple ...
Van Cauwenbergh Deborah D Pain in Motion Research Group, Departments of Human Physiology and Rehabilitation Sciences, Faculty of Physical Education & Physiotherapy, Vrije Universiteit Brussel, Belgium; Pain in Motion Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, - - 2014
It is hypothesized that the autonomic nervous system responds differently to various stressors in patients with chronic fatigue syndrome (CFS) compared to healthy controls. The goal is to systematically review the scientific literature addressing the functioning of the autonomic nervous system in patients with CFS. All studies that were identified ...
Choudhury Supriyo - - 2014
Objectives: Levodopa-induced dyskinesia (LID) is one of the most disabling complications of long-term pharmacotherapy of Parkinson's disease (PD). The objective of our study was to examine the clinical profile and determinants of severity of LID in Indian PD patients on levodopa therapy. Methods: Retrospective analysis of records of PD patients ...
Busse Stefan S Department of Psychiatry, University of Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany, - - 2014
N-methyl-D-aspartate glutamate receptors (NMDA-R) play a key role in learning and memory. Therefore, they may be involved in the pathophysiology of dementia. NMDA-R autoantibodies directed against the NR1a subunit of the NMDA-R, which were first identified as a specific marker for a severe form of encephalitis, cause a decrease in ...
Prinzi Natalie N Department of Experimental Medicine, "Sapienza" University of Rome, Viale del Policlinico, 155, 00161, Rome, - - 2014
Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central ...
Xie Yong Y Division of Cardiology, Columbia University Medical Center, New York, New York; Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; Department of Cardiology, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, - - 2014
The aim of this study was to report the frequency, patient and lesion-related characteristics, and outcomes of subclinical, nonculprit plaque ruptures in the PROSPECT (Providing Regional Observations to Study Predictors of Events in the Coronary Tree) study. Plaque rupture and subsequent thrombosis is the most common cause of acute coronary ...
Li Xiao-Lin - - 2014
Red cell distribution width (RDW) has been recognized as a novel marker for several cardiovascular diseases. The aim of this study was to evaluate the association between RDW levels and the presence of isolated coronary artery ectasia (CAE). We studied 414 subjects including 113 patients with isolated CAE (Group A), ...
Agosta Federica F Neuroimaging Research Unit, Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, - - 2014
White matter (WM) tract alterations were assessed in patients with progressive supranuclear palsy (PSP) relative to healthy controls and patients with idiopathic Parkinson's disease (PD) to explore the relationship of WM tract damage with clinical disease severity, performance on cognitive tests, and apathy. 37 PSP patients, 41 PD patients, and ...
Okada Takuya T Department of Cardiovascular and Interventional Radiology, Assistance Publique des Hôpitaux de Paris, Georges Pompidou European Hospital, 75015, Paris, France, - - 2014
To classify the renal artery (RA) anatomy based on specific requirements for endovascular renal artery denervation (RDN) in patients with drug-resistant hypertension (RH). The RA anatomy of 122 consecutive RH patients was evaluated by computed tomography angiography and classified as two types: A (main RA ≥20 mm in length and ≥4.0 mm ...
Liu Aihua A Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, TiantanXili 6, Dongcheng District, Beijing, 100050, China, - - 2014
Because of complex angioarchitecture, the transarterial or venous pathway is not feasible for some cavernous sinus dural arteriovenous fistulas (CS DAVFs). We present six cases in which onyx embolization of a CS DAVFs was made possible through direct transorbital puncture. In the present study, all patients were penetrated through one ...
Kilicaslan Baris B Department of Cardiology, İzmir Tepecik Research and Training Hospital, Izmir, - - 2014
Abnormal left ventricle (LV) geometric patterns are associated with an increased risk of vascular complications of hypertension (HT). The association between red-cell distribution width (RDW) and HT has been recently investigated; however, the relationship between abnormal LV geometric patterns and RDW has not been studied before. The aim of this ...
Ichihashi Shigeo S Department of Radiology, Nara Medical University, Nara, - - 2014
The ankle-brachial index (ABI) determined by the oscillometric method has been shown to reliably detect peripheral arterial disease (PAD), with highly correlations with the Doppler method. However, most of these studies were shown in cohorts with a small number of PAD patients, and no imaging studies have been performed. The ...
Di Liberato Lorenzo L Department of Medicine, Institute of Nephrology, "SS. Annunziata" Hospital, G. d'Annunzio University of Chieti-Pescara, Via dei Vestini, 66013, Chieti, - - 2014
Carnitine metabolism in patients on peritoneal dialysis (PD), particularly automated PD (APD), has not been extensively evaluated. Here, we examined levels of a large number of carnitine species in plasma from adult uremic patients treated with continuous ambulatory PD (CAPD) or APD, vetting whether L-carnitine may be used in the ...
Fischer Sabine S University Children's Hospital Basel, Spitalstrasse 33, Basel, 4506, - - 2014
The cblC defect is the most common inborn error of vitamin B12 metabolism. Despite therapeutic measures, the long-term outcome is often unsatisfactory. This retrospective multicentre study evaluates clinical, biochemical and genetic findings in 88 cblC patients. The questionnaire designed for the study evaluates clinical and biochemical features at both initial ...
Shindo Akihiro A Department of Neurology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan, - - 2014
The clinical symptoms, causative factors, and prognosis in Japanese patients with cerebral venous thrombosis have not been adequately characterized. The present study describes these features in patients in Japan. Twenty-two patients with cerebral venous thrombosis were retrospectively identified. Diagnosis was confirmed by either digital subtraction angiography, magnetic resonance venography, or ...
Gao Feng F Department of Gastroenterology, People's Hospital of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang Uyghur Autonomous Region, - - 2014
We aimed to study the association between HLA-DRB1 alleles and anti-neutrophil cytoplasmatic antibodies (ANCA) among Uyghur and Han patients with ulcerative colitis (UC) in China. Altogether 160 UC patients and 466 healthy controls of Uyghur and Han populations both residing in the Xinjiang Uyghur Autonomous Region (XUAR) of China were ...
Singh Siddharth S Division of Gastroenterology and - - 2014
Though hepatic involvement is common in patients with hereditary haemorrhagic telangiectasia (HHT), symptomatic liver disease is rare but potentially fatal without liver transplantation. Factors associated with clinically significant liver disease in patients with HHT are unknown. In this prospective cohort study, we included consecutive patients from 2001 to 2011 with ...
Jura-Półtorak Agnieszka A Department of Clinical Chemistry and Laboratory Diagnostics, Medical University of Silesia, Katowice, Poland. Electronic address: - - 2014
Qualitative and quantitative evaluation of plasma glycosaminoglycans (GAGs) of rheumatoid arthritis (RA) patients in relation to disease activity estimated by DAS28 score was evaluated. GAGs were quantified by hexuronic acid assay and electrophoretic fractionation. Keratan sulfate (KS) and hyaluronic acid (HA) were measured by immunoassay. Chondroitin/dermatan sulfate (CS/DS) and heparan ...
Gorur Gozde D GD Departments of aNuclear Medicine bCardiology, Kocaeli University School of Medicine, Kocaeli, Turkey cDepartment of Radiology, Oregon Health and Science University, Portland, Oregon, - - 2014
Our aim was to compare the radioiodine uptake (RAIU) of congestive heart failure (CHF) patients with that of a control group and investigate the prognostic value. We also assessed correlations of RAIU with other clinical parameters. A total of 32 CHF patients and 14 controls were included in this study. ...
Fabbri M M IRCCS Institute of Neurological Science, Bologna, Italy; Clinical Pharmacology Unit, Faculty of Medicine, Instituto de Medicina Molecular, University of Lisbon, Lisbon, - - 2014
Olfactory dysfunction is common in Parkinson's disease (PD) and it is one of the earliest non-motor symptoms. A few studies have suggested that deep brain stimulation of the subthalamic nucleus (STN-DBS) could improve olfactory function. Our aim was to evaluate the acute effect of bilateral STN-DBS on a commonly used ...
van Staa Tjeerd P TP London School of Hygiene & Tropical Medicine, London, United Kingdom; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the - - 2014
To evaluate clinical risk factors associated with myotoxicity in statin users. Cohort study of patients prescribed a statin in UK primary care practices contributing to the Clinical Practice Research Datalink. Outcomes of interest were creatine phosphokinase (CPK) levels and clinical records of rhabdomyolysis. The cohort comprised 641703 statin users. Simvastatin ...
Nery Pablo B PB University of Ottawa Heart Institute, Division of Cardiology, Department of Medicine, Ottawa, - - 2014
Atrioventricular block(AVB) can be caused by several conditions including cardiac sarcoidosis(CS). The prevalence of CS causing this presentation in a North American population has not been investigated and was the purpose of this study. We prospectively evaluated patients aged 18 to 60 years presenting with unexplained 2(nd) or 3(rd) degree ...
Carpenter G G Salivary Research Unit, King's College London Dental Institute, London, - - 2014
Oral health is dependent upon a thin mobile film of saliva on soft and hard tissues. Salivary proteins adhere to teeth to form the acquired enamel pellicle which is believed to protect teeth from acid erosion. This study investigated whether patients suffering diet-induced dental erosion had altered enamel pellicles. Thirty ...
Cui W W Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS, - - 2014
Multiparameter flow cytometry (MFC) is commonly used to detect minimal residual disease (MRD) during the course of chemotherapy or relapse. Only one study addressed the immunophenotypic changes in refractory disease. We studied changes in leukemia-associated aberrant immunophenotype (LAIP) in patients with refractory and relapsed acute myeloid leukemia (AML). We analyzed ...
Chen J J Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Recent studies found that microembolic signals (MESs) could be detected by transcranial Doppler in patients with moyamoya disease. However, the clinical significance of MESs in moyamoya disease remains unclear. Our aim was to investigate whether the MESs could predict cerebral ischaemic events in patients with moyamoya disease. Fifty-four consecutive patients ...
van Gaalen Judith J Departments of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Center, Nijmegen, The - - 2014
Several studies have suggested that language impairment can be observed in patients with cerebellar pathology. The aim of this study was to investigate language performance in patients with spinocerebellar ataxia type 6 (SCA6). We assessed speech and language in 29 SCA6 patients with standardized linquistic tests and correlated this with ...
Kou K K Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, - - 2014
Atopic dermatitis (AD) is a chronic inflammatory skin disease in which T helper 2 (Th2)-type immune responses are dominant. Keratinocytes persistently secrete proinflammatory cytokines and chemokines, amplifying Th2-type responses in AD. Recent findings indicate that periostin, an extracellular matrix protein induced by Th2 cytokines, plays a critical role in the ...
Dobesberger Judith J Department of Neurology, Paracelsus Medical University, Christian Doppler Klinik, Ignaz Harrer Straße 79, A-5020 Salzburg, Austria; Department of Neurology, Innsbruck Medical University, Anichstraße 35, A-6020 Innsbruck, Austria. Electronic address: - - 2014
Selective serotonin reuptake inhibitors (SSRIs) are often used in the treatment of depressive disorders in patients with epilepsy. Pro- and anti-convulsive effects of SSRIs are discussed controversially. The aim of this study was to investigate a possible impact of SSRIs-treatment on duration of EEG and clinical features in epilepsy patients. ...
Hübbe-Tena Claudia C Department of Rheumatology, Department of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Department of Dermatology, Hospital General de Zona 1-A Dr Rodolfo Antonio de Mucha Macías, Instituto Mexicano del Seguro Social, Division of Research, Department of Echocardiography and Cardio Respiratory Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, - - 2014
Objective. The aim of this study was to investigate whether a core of echocardiography-based definitions of pulmonary hypertension (PH), as proposed by the European Society of Cardiology, European Respiratory Society and International Society of Heart and Lung Transplantation (ESC/ERS/ISHLT), may predict long-term survival in patients with SLE.Methods. A post hoc ...
Kampschreur Linda M LM Division of Medicine, Dept. of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, - - 2014
Coxiella burnetii causes Q fever, a zoonosis, which has acute and chronic manifestations. From 2007 to 2010, the Netherlands experienced a large Q fever outbreak, which has offered a unique opportunity to analyze chronic Q fever cases. In an observational cohort study, base-line characteristics, clinical characteristics, as well as mortality ...
Przybyłkowski Adam - - 2014
Wilson's disease (WD) can manifest itself in different clinical forms, the neurological and hepatic ones being the most common. It is suggested that neurological signs and psychiatric symptoms develop secondary to liver involvement. The aim of this study was to characterize the liver disease in patients newly diagnosed with the ...
Schukfeh Nagoud N Division of Paediatric Surgery, Department of General-Visceral and Transplant Surgery, University Hospital, University Duisburg-Essen, Essen, - - 2014
During LTX, there may be a risk that pathogens of the native liver are released into the systemic circulation. No investigations on incidence/spectrum of pathogens in native livers have been published. We hypothesized that pathogens are found in the native liver of a large proportion of pediatric patients during LTX ...
Vasileiadis Ioannis I Department of Otolaryngology/Head and Neck Surgery, Venizeleio - Pananeio General Hospital, Herakleion, Alexandroupolis, Greece, - - 2014
Hashimoto thyroiditis (HT) is associated with an increased risk of developing papillary thyroid carcinoma (PTC). The relationship between thyroid autoimmunity and cancer remains controversial. The purpose of this study was to investigate whether the preoperative TgAb could be a potential predictor of PTC in patients with thyroid nodules and to ...
Avci Ahmet A Faculty of Medicine, Cardiology Department, Selcuk University, Konya, - - 2014
Systemic lupus erythematosus (SLE) is a chronic disease that affects many organ systems and manifests a broad spectrum of laboratory and clinical features. SLE patients have an increased risk of developing cardiovascular disease. The aim of this study was to evaluate inhomogeneities of repolarization by using Tpeak -Tend (Tp-e) interval ...
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