Search Results
Results 601 - 650 of 17758
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Greywoode Ruby R Department of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, - - 2014
To investigate a recent association between the use of the angiotensin receptor-blocker (ARB) olmesartan and a severe enteropathy resembling celiac disease. We searched our endoscopy database for all outpatient esophagogastroduodenoscopy (EGD) or colonoscopy examinations in patients aged at least 50 years during the period January 1, 2007, to March 31, ...
Margallo Victor S VS Hypertension Program, University Hospital Clementino Fraga Filho, Medical School, Universidade Federal do Rio de Janeiro, - - 2014
Obstructive sleep apnea (OSA) is strongly associated with resistant hypertension. The Berlin questionnaire is the most widely used screening tool to identify patients at high risk of having OSA. The objective was to test the diagnostic accuracy of the Berlin questionnaire in detecting OSA in resistant hypertensive patients. A cross-sectional ...
Esposito Francesco F *Department of Radiology - "Santobono-Pausilipon" Hospital - Naples- Italy †Department of Radiology - University Hospital "Federico II" - Naples - Italy ‡Section of Ultrasonography and Interventional Ultrasound - "D. Cotugno" Hospital - Naples - Italy §4 Department of Radiology -Santa Maria alla Gruccia Hospital - zona Valdarno - Azienda USL8 Arezzo - - - 2014
Midgut volvulus with malrotation is typical in newborns. We present our experience to underline the importance of suspecting midgut volvulus as cause of abdominal pain also beyond infancy, particularly in relationship with malrotation, and the relevance of ultrasonographic (US) signs in its diagnosis. 34 patients (10 M, 24 F; aged between ...
Tujios Shannan R SR Division of Digestive and Liver Diseases, UT Southwestern Medical Center at Dallas, - - 2014
Patients with acute liver failure (ALF) frequently develop renal dysfunction, yet its overall incidence and outcomes have not been fully assessed. We investigated the incidence of acute kidney injury (AKI) among patients with ALF, using defined criteria to identify risk factors and to evaluate its effect on overall outcomes. We ...
Sana Aria A Departments of Gastroenterology and Hepatology, Erasmus MC - University Medical Center, Rotterdam, The Netherlands. Electronic address: - - 2014
Chronic gastrointestinal ischemia (CGI) is more common than previously thought. Visible light spectroscopy (VLS) allows for non-invasive measurements of mucosal capillary hemoglobin oxygen saturation during endoscopy. We evaluated the response of patients with occlusive CGI to treatment following evaluation by radiologic imaging of the vasculature and VLS. We also identified ...
Yan Li-Rong LR aKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, State Key Laboratory of Cardiovascular Diseases bDepartment of Radiology cDepartment of Pathology and Physiology dDepartment of Echocardiography, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Midventricular obstructive hypertrophic cardiomyopathy (MVOHCM) is a rare form of hypertrophic cardiomyopathy. Knowledge regarding the diagnosis, morbidity and cardiovascular mortality is limited. In this study, we aimed to describe the long-term outcomes of patients with MVOHCM followed in a tertiary referral centre.Methods A retrospective study of 60 patients with MVOHCM ...
Casas Francisco F Unidad de Gestión Clínica de Neumología, Hospital Universitario San Cecilio, Granada, - - 2014
The effect of hereditary alpha-1 antitrypsin (AAT) deficiency can manifest clinically in the form of chronic obstructive pulmonary disease (COPD). AAT deficiency (AATD) is defined as a serum concentration lower than 35% of the expected mean value or 50mg/dl (determined by nephelometry). It is associated in over 95% of cases ...
Hoshina Takayuki T Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. Electronic address: - - 2014
The aim of this study is to investigate the utility of several biomarkers in differentiating bacterial community-acquired lower respiratory tract infection (CA-LRTI) from non-bacterial CA-LRTI in children and the difference of their diagnostic performance between pneumonia and bronchitis. A retrospective cohort study composed of 108 pediatric patients hospitalized for CA-LRTI ...
Koenekoop Robert K RK McGill Ocular Genetics Laboratory and Paediatric Ophthalmology, Montreal Children's Hospital, Departments of Paediatric Surgery, Human Genetics and Ophthalmology, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: - - 2014
Leber congenital amaurosis, caused by mutations in RPE65 and LRAT, is a severe form of inherited retinal degeneration leading to blindness. We aimed to assess replacement of the missing chromophore 11-cis retinal with oral QLT091001 (synthetic 9-cis-retinyl acetate) in these patients. In our open-label, prospective, phase 1b trial, we enrolled ...
Khanna Neena N Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, - - 2014
Gonadal involvement in males in lepromatous leprosy is not uncommon, but there is a paucity of literature on the involvement of gonads in female patients with leprosy. This study was undertaken to determine if there is any menstrual dysfunction, alteration in fertility status and circulating luteinizing hormone (LH), follicle-stimulating hormone ...
Schneider Birke B Medizinische Klinik II, Sana Kliniken Lübeck, Germany. Electronic address: - - 2014
This study evaluated the frequency, severity and outcome of complications in the clinical course of tako-tsubo cardiomyopathy (TTC). TTC is regarded as a benign disease since left ventricular (LV) function returns to normal within a short time. However, severe complications have been reported in selected patients. From 37 hospitals, 209 ...
Westover M Brandon MB Department of Neurology, Epilepsy Service, Massachusetts General Hospital, Wang 720, Boston, MA 02114, USA. Electronic address: - - 2014
To characterize the risk for seizures over time in relation to EEG findings in hospitalized adults undergoing continuous EEG monitoring (cEEG). Retrospective analysis of cEEG data and medical records from 625 consecutive adult inpatients monitored at a tertiary medical center. Using survival analysis methods, we estimated the time-dependent probability that ...
Nytrova Petra P Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, General University Hospital, Charles University in Prague, Czech Republic; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address: - - 2014
The role of complement has been demonstrated in experimental models of neuromyelitis optica (NMO), however, only few studies have analysed complement components longitudinally in NMO patients. We measured serum or plasma concentrations of anti-C1q antibodies and complement split products C3a and C4a and soluble C5b-9 in patients with NMO, multiple ...
Aytaç Bilal B Department of Biochemistry, Ministry of Health, Medical School of Ankara University, Ankara, Turkey, - - 2014
Migraine patients have an increased risk to develop deep white matter hyperintensities (WMH) than the general population. Oxidative stress is believed to play a role in the pathogenesis of migraine. The present study was undertaken to assess oxidant/antioxidant balance of migraineurs with and without WMH. We hypothesized that increased oxidative ...
Cabuk Gizem G Department of Cardiology, Turkey Yuksek Ihtisas Education and Research Hospital, Ankara, - - 2014
The sclerotic lesions of the aortic valve share common features with atherosclerosis. An anti-inflammatory protein, adiponectin, seems to have a protective effect on the cardiovascular system. The goal of our study is to determine adiponectin levels in patients with aortic sclerosis and to compare these values with the control group ...
Roldán V - - 2014
There are few biomarkers able to forecast new thrombotic events in patients with AF. In this framework, microRNAs have emerged as critical players in cardiovascular biology. In particular, miR-146a-5p is recognised as an important negative regulator of inflammation. This study aims to evaluate the prognostic role and biological effect of ...
Laterza Rosa Maria RM Department of General Gynecology and Gynecologic Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria, - - 2014
The aim of this study was to evaluate pelvic floor dysfunction and anatomical signs of pelvic organ prolapse (POP) in patients with levator ani muscle (LAM) trauma compared with patients with an intact LAM 1 year postpartum. In a prospective case-control study, primiparous women after vaginal delivery, with LAM trauma diagnosed ...
Marek Josef J Third Department of Medicine, First Medical Faculty, Charles University, U nemocnice 1, 128 02, Prague 2, Czech - - 2014
This paper presents our 18 years of experience in treating ACTH secreting adenomas (Cushing's disease and Nelson's syndrome) using the Leksell gamma knife (LGK) irradiation. Twenty-six patients with Cushing's disease were followed-up after LGK irradiation for 48-216 months (median 78 months). Seventeen patients had undergone previous surgery, in nine patients LGK irradiation was ...
Inal Salih S Department of Internal Medicine, Division of Nephrology, Süleyman Demirel University Medical School , Isparta , Turkey - - 2014
Abstract Introduction: Long-term exposure to dialysis solutions is an important contributor to the ongoing inflammatory process in peritoneal dialysis (PD) patients. Some studies have shown amelioration of this adverse effect with biocompatible solutions. We aimed to compare the neutrophil-to-lymphocyte (N/L) ratio in PD patients using biocompatible and standard solutions and ...
Roulin Marie-José MJ Institute of Higher Education and Nursing Research, Lausanne University-CHUV, 1010 Lausanne, Switzerland, - - 2014
The primary objective of this study was to describe the frequency of behaviors observed during rest, a non-nociceptive procedure, and a nociceptive procedure in brain-injured intensive care unit (ICU) patients with different levels of consciousness (LOC). Second, it examined the inter-rater reliability and discriminant and concurrent validity of the behavioral ...
Otsuka Kenichiro K Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, - - 2014
Arterial stiffness is a significant predictor of cardiovascular disease (CVD), the risk of which is modified by medications for atherosclerotic risk factors and life-style changes. Cardio-ankle vascular index (CAVI) provides noninvasive, objective information on arterial stiffness, independent of blood pressure. This study aimed to investigate changes in CAVI after management ...
Arends Pauline P Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The - - 2014
Hepatocellular carcinoma (HCC) risk-scores may predict HCC in Asian entecavir (ETV)-treated patients. We aimed to study risk factors and performance of risk scores during ETV treatment in an ethnically diverse Western population. We studied all HBV monoinfected patients treated with ETV from 11 European referral centres within the VIRGIL Network. ...
Lou M M From the Departments of Neurology (M.L., Z.C., J.W., H.H., X.C., Z.S.) and Radiology (J.S.), the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China. hzzjsjz@163.com - - 2014
Asymmetric hypointensity of cerebral veins on susceptibility-weighted imaging has been shown to indirectly reflect tissue hypoxia after cerebral ischemia. We therefore investigated whether patients with prominent asymmetry of the cerebral veins on SWI and a relatively small diffusion-weighted imaging lesion (SWI-DWI mismatch), representing the presence of salvageable tissue, were more ...
McNicholl Adrian G AG aHospital of La Princesa, and Instituto de Investigación Sanitaria Princesa bCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain Gastroenterology Units of cHospital Mutua de Terrassa, Terrassa dHospital del Mar, Barcelona eHospital Rio Hortega, Valladolid fHospital de Cabueñes, Gijon gHospital Costa del Sol, Malaga hHospital San Jorge, Huesca iHospital Clínico de Zaragoza, Zaragoza jHospital Virgen de la Salud, - - 2014
It has been suggested that GastroPanel might be a useful tool for the diagnosis of chronic atrophic gastritis (CAG) measuring four biomarkers in blood: basal gastrin-17 (G17), pepsinogen I and II (PGI and PGII), and Helicobacter pylori antibodies. To determine the accuracy of GastroPanel for the diagnosis of CAG. This ...
Sildiroglu Onur O *Department of Radiology, University of Virginia, Charlottesville, VA †Radiology, Gulhane Medical School, Istanbul, Turkey ‡Department of Interventional Radiology, Rush University Medical Center, Chicago, - - 2014
To report the outcomes following catheter angiography with or without embolization in patients with acute upper gastrointestinal nonvariceal hemorrhage (UGINH). A review of electronic medical records was performed to identify all potential patients for this study between 2001 and 2011. Patients with first-time UGINH who required angiographic localization and endovascular ...
Baturova Maria A MA Department of Cardiology, Clinical Sciences, Lund University, SE-221 85 Lund, Sweden Research, Clinical and Educational Center 'Cardiology', St. Petersburg State University, St. Petersburg, Russia - - 2014
Data from national discharge registers are commonly used to estimate prevalence and incidence of atrial fibrillation (AF) in epidemiology studies. However, sensitivity and specificity of register-based AF diagnosis have not been evaluated. We sought to assess the validity of AF diagnosis in the Swedish Patient Register against electrocardiography (ECG) documentation ...
Kulke Matthew H MH M Kulke, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 02115, United States - - 2014
Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. In this prospective, randomized study, patients with evidence of carcinoid ...
Honda Hirokazu H Division of Nephrology, Department of Medicine, Showa University Koto Toyosu Hospital, Tokyo, Japan. Electronic address: - - 2014
Inflammation contributes to hemopoiesis by lowering responses to epoetin (EPO) and to an increase in the mortality of patients on hemodialysis. However, nutritional status might alter associations among inflammation, EPO responsiveness, and the risk of mortality. We assessed the effect of inflammation on mortality according to nutritional status among EPO ...
Chan Maria M Department of Nutrition and Dietetics, St. George Hospital, Sydney, New South Wales, Australia; Illawarra Health and Medical Research Institute, School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia; St. George Clinical School, School of Medicine, University of New South Wales, Sydney, Australia. Electronic address: - - 2014
To describe the baseline nutritional characteristics of a cohort of end-stage kidney disease (ESKD) patients attending a pre-dialysis clinic. Outpatient clinic of a metropolitan tertiary teaching hospital in Sydney, Australia. All ESKD patients attending the multidisciplinary pre-dialysis assessment clinic between April 2002 and March 2008. Retrospective analysis of data extracted from ...
Jochheim D D Cardiology Department, Munich University Clinic, Germany. Electronic address: - - 2014
To identify independent predictors of contrast medium-induced acute kidney injury (CI-AKI) after enhanced multidetector-row computed tomography (MDCT) prior to transcatheter aortic valve implantation (TAVI) in high-risk patients. The present single-centre study analysed retrospectively 361 patients who were assessed using MDCT prior to TAVI. CI-AKI was defined as an increase in ...
Liu Xi X Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an, - - 2014
Alterations in the cerebral circulation time (CCT) are observed in several cerebrovascular diseases. We designed a new method of global CCT measurement using gray-scale contrast-enhanced ultrasound and studied healthy Chinese adults and patients with intracranial shunts. Eighty-one healthy volunteers and eight patients with intracranial shunt disease were enrolled. The contrast ...
Ni Zhaohui - - 2014
Primary IgA nephropathy (IgAN) is the most common form of idiopathic glomerulonephritis worldwide. Although most patients are able to achieve remission with the current therapy, a large number of patients will still progress to end-stage renal disease. This study aimed to evaluate kidney disease progression and the risk factors for ...
Frasca D D Department of Anaesthesia and Intensive Care, University Hospital of Poitiers, Poitiers, - - 2014
Respiratory depression, a potentially serious complication after general anaesthesia, can be detected promptly by close monitoring of both oxygen saturation and respiratory rate. Obese patients have morphological changes that may impair the reliability of monitoring devices. In this study, respiration rate was simultaneously recorded every second for up to 60 min ...
Gouda Zaghloul Z Nephrology Department, Damanhur Medical National Institute, General Organization of Teaching Hospitals and Institutes, Damanhur - - - 2014
Venous catheters provide access for hemodialysis (HD) when patients do not have functioning access device. Obstruction of jugular, femoral or even external iliac vessels further depletes options. Subclavian approach is prohibited. Catheterization of inferior vena cava requires specialized equipment and skills. The purpose is to assess a new lifesaving HD ...
Kuroda Hidekatsu H Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, 020-8505, - - 2014
We measured liver stiffness (LS) in patients with acute liver failure (ALF) using acoustic radiation force impulse (ARFI) elastography and investigated the usefulness of measuring LS for predicting the prognosis of ALF patients. From April 2010 to December 2013, we evaluated 63 patients with acute liver disease. The subjects included ...
Noppe G G Department of Paediatrics, Division of Endocrinology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, the - - 2014
Glucocorticoid replacement therapy in patients with adrenal insufficiency needs to be tailored to the individual patient based on body composition and clinical signs and symptoms as no objective method for assessment of treatment adequacy is available. Current treatment regimens are often not satisfactory, which is shown by the adverse metabolic ...
Ritvonen Elina E Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital and University of - - 2014
Previous studies report impaired health-related quality of life (HRQoL) in patients with functional pituitary adenomas (FPA). We assessed HRQoL in FPA patients having undergone surgery at our University Central Hospital between 2000 and 2010, with combined adjuvant treatment given to achieve strict hormonal control. A cross-sectional study including a large ...
Kato Motoyasu - - 2014
Non-small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) need to be approached carefully given the high incidence of pulmonary toxicity. Pemetrexed (PEM) is the key drug for the treatment of NSCLC. However, its safety, especially with respect to the exacerbation of ILD, and efficacy in NSCLC patients ...
Gromov Kirill K Harris Orthopaedic Laboratory, Massachusetts General Hospital, Boston, Massachusetts; Department of Orthopaedic Surgery, Copenhagen University Hospital, Hvidovre, Copenhagen, - - 2014
Precise indications for THA remain unclear and regional differences might exist in selecting patients for surgery. In this study we investigate radiological OA grade and self-reported quality of life in 909 patients undergoing THA in 16 centers across US and Europe. Patients in US were younger and had higher BMI. ...
An Jie J aMedical Imaging Center, Nanfang Hospital, Southern Medical University bMedical Imaging Center, Guangdong 999 Brain Hospital, Guangzhou cCollege of Mechatronics and Automation, National University of Defense Technology, Hunan, - - 2014
Statistical analysis on diffusion tensor imaging has been used extensively in mesial temporal lobe epilepsy (mTLE) and most studies report decrease in fractional anisotropy (FA) in multiple white matter regions. However, these findings vary across studies and between regions. Therefore, in this study, we used tract-based spatial statistics along with ...
Zhang Yun-Fang YF Center of Kidney Disease, Huadu District People's Hospital, Southern Medical University , Guangzhou , China - - 2014
Abstract Association of vitamin D receptor (VDR) BsmI (rs1544410) gene polymorphism with the intact parathyroid hormone (iPTH) level among patients with end-stage renal disease (ESRD) from the published reports is still conflicting. This meta-analysis was performed to evaluate the relationship between VDR BsmI (rs1544410) gene polymorphism and the iPTH level ...
Shi Doufei D Department of Cardiology, Shandong Provincial Hospital, Shandong University, NO. 324 Jing Wu Road, Jinan, 250021, People's Republic of - - 2014
The study was aimed to evaluate the right ventricular function in pneumoconiosis patients by real-time three-dimensional echocardiography. A total of 80 individuals including 44 consecutive pneumoconiosis patients and 36 age- and gender-matched healthy volunteers as controls were prospectively recruited for the study. All the patients underwent two- and three-dimensional echocardiography. ...
Erginel Başak B 1Department of Pediatric Surgery, Sisli Etfal Education and Research Hospital, Istanbul, - - 2014
Medical records of 71 children with Wilms' tumor at Sisli Etfal Education and Research Hospital between 1990 and 2014 were reviewed. Mean age at diagnosis was 3.11 years (2 days-7 years). Male to female ratio was M/F = 6/10. The incidence of associated anomaly was 16.9%. Clinical manifestations included abdominal mass (89%), hematuria ...
Floeter Mary Kay MK From the National Institute of Neurological Disorders and Stroke (M.K.F., R.K., M.P.K., O.S., M.S., L.D., T.W., A.M.), NIH, Bethesda, MD; and Departments of Psychiatry and Neurology (E.D.H.), Columbia University, New York, NY. - - 2014
The objectives of the study were (1) to determine the prevalence and characteristics of pseudobulbar affect (PBA) in patients with primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) in an outpatient clinic population, and (2) to test the hypothesis that damage of inputs to the cerebellum, leading to cerebellar ...
Hsu Cheng-Teng CT School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan. Electronic address: - - 2014
In response to reduce erroneous readings due to miscoding when performing self-monitoring blood glucose (SMBG), this study introduces a user-friendly SMBG biosensor with an innovative auto-coding module on the meter and strip. Actual users characterized the performance of SMBG systems. A total of 105 patients were incorporated the study and ...
Poynard Thierry T Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière, Paris, France; University Pierre et Marie Curie (UPMC) Univ Paris 06, Paris, France; INSERM, UMR_S 938, Paris, France. Electronic address: - - 2014
The first aim was to extend the validation of FibroTest (FT) and transient elastography (TE) as markers of occurrence of cirrhosis without complications (F4.1), esophageal varices (F4.2), and severe complications (F4.3) in patients with chronic hepatitis B (CHB). The second aim was to validate a previous definition of inactive carrier ...
Heard Takijah T TT Neurology, Boston Children's Hospital, Boston, - - 2014
We describe the seizure and EEG characteristics in a population of children with known Fragile X. The medical records of 135 genetically confirmed FXS patients receiving care in a Fragile X clinic and their available EEG reports were reviewed. The mean age was 5.94 years old including 18 males and ...
Alexandridis E E Centre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, - - 2014
Transnasal endoscopy (TNE) with ultrathin endoscopes has been advocated as an attractive alternative, for diagnostic upper endoscopy. To assess tolerability, acceptability and quality of TNE, in comparison with standard upper endoscopy (SOGD, standard oesophago-gastro-duodenoscopy) under local anaesthetic. We prospectively recruited 157 patients (83 females/74 males) mean age 57 years. The Fujinon ...
Chiu Terry Ting-Yu TT Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang-Gung University College of Medicine, Kaohsiung, - - 2014
Protein-energy wasting (PEW) contributes to mortality in hemodialysis (HD) patients. Adipokines regulate energy homeostasis and body weight. Circulating gelsolin can modulate inflammation and is correlated with HD mortality. Whether adipokines and gelsolin play important roles in PEW remains unclear. Based on the criteria proposed by the International Society of Renal ...
Sato Ryuta R Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan, - - 2014
A new Japanese histologic classification (JHC) of immunoglobulin A nephropathy (IgAN) for prediction of long-term prognosis was proposed in 2013. The goal of this study was to validate the JHC system in a Japanese single-center cohort. A retrospective study was conducted in 198 Japanese adult patients with IgAN. Clinical findings ...
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