Search Results
Results 501 - 550 of 17758
< 6 7 8 9 10 11 12 13 14 15 16 >
Sonbay N D ND Department of Otorhinolaryngology,Yalvac Government - - 2014
Objective: This study aimed to determine the characteristics of hearing loss in patients with Behçet's disease. Methods: Twenty-six consecutive patients with Behçet's disease and a control group consisting of 25 age-matched healthy subjects were prospectively included in this study. Pure tone and speech audiometry, tympanometry, distortion product otoacoustic emission testing, ...
Díez Juan J JJ Department of Endocrinology, Hospital Universitario Ramón y Cajal, Madrid, Spain, - - 2014
Our aim was to evaluate the effectiveness of off-label use of sunitinib in patients with advanced differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAI) therapy. We performed a retrospective analysis of patients treated in the setting of clinical practice in a University General Hospital. Eleven consecutive patients (5 women, ...
Penning Marlies E ME Departments of Pathology and - - 2014
Preeclampsia is characterized by hypertension and proteinuria, and increased shedding of podocytes into the urine is a common finding. This finding raises the question of whether preeclamptic nephropathy involves podocyte damage. This study examined podocyte-related changes in a unique sample of renal tissues obtained from women who died of preeclampsia.DESIGN, ...
Sakimoto Tohru - - 2014
To investigate morphological changes in meibomian glands in patients with granular corneal dystrophy type 2 (GCD2) using non-invasive meibography. Eleven patients (3 men and 8 women) with GCD2, and sex-matched and age-matched healthy volunteers as a controls were enrolled in this study. The diagnosis of GCD2 was confirmed by transforming ...
Kinsella J A JA Department of Neurology, The Adelaide and Meath Hospital, Dublin, incorporating the National Children's Hospital, Trinity College Dublin, Dublin, - - 2014
The importance of thrombin generation in the pathogenesis of TIA or stroke and its relationship with cerebral microembolic signals (MES) in asymptomatic and symptomatic carotid stenosis has not been comprehensively assessed. Plasma thrombin generation parameters from patients with moderate or severe (≥50%) asymptomatic carotid stenosis were compared with those from ...
Friberg Leif L From the Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden (L.F., M.R.); Department of Cardiology, Danderyd Hospital, Stockholm, Sweden (L.F., M.R.); Division of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden (A.L., B.N.); Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden (A.T.); and Riks-Stroke, Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden (K.A.). - - 2014
Atrial fibrillation (AF) is a common cause of devastating but potentially preventable stroke. Estimates of the prevalence of AF among patients with stroke vary considerably because of difficulties in detection of intermittent, silent AF. Better recognition of AF in this patient group may help to identify and offer protection to ...
Park Kyu Hyung KH Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University Bundang Hospital, #300, Gumi-dong, Bundang-gu, Seongnam, Gyeonggi-do, 463-707, Korea (South), Republic - - 2014
Purpose:To investigate the associations of the Wnt modulators Wnt inhibitory factor 1 (WIF-1) and Dickkopf 3 (DKK-3) in the aqueous humor (AH) with neovascular age-related macular degeneration (nAMD) and to determine their clinical implications. Methods:Seventy-four nAMD patients initially treated with an intravitreal injection of ranibizumab (IVR) and 74 age- and ...
Zabini Diana D Ludwig Boltzmann Institute for Lung Vascular Research, Graz, - - 2014
Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with chronic inflammation but the pathological mechanisms are largely unknown. Our study aimed to simultaneously profile a broad range of cytokines in the supernatant of pulmonary endarterectomy (PEA) surgical material, as well as prospectively in patients with CTEPH to investigate whether circulating cytokines ...
Park In-Seok IS Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, South - - 2014
Several studies have demonstrated that patients with essential tremor (ET) may also have mild cognitive impairments (MCIs), and cross-sectional and population-based studies have shown that ET is associated with prevalent dementia. Different presentations of MCI are suggested to be associated with different pathologies. For example, amnestic MCI may be associated ...
Zielonka Matthias M Division of Inherited Metabolic Diseases, Department of General Pediatrics, University Hospital Heidelberg, Heidelberg, - - 2014
Glutaric aciduria type I is a rare metabolic disorder caused by deficiency of glutaryl-coenzyme A dehydrogenase. Chronic subdural hematomas have been reported in glutaric aciduria type I and are considered as important differential diagnosis of nonaccidental head trauma. However, chronic subdural hematomas are usually thought to remain clinically silent in ...
Sahama Ishani I The University of Queensland, School of Medicine, Brisbane, - - 2014
Magnetic resonance imaging (MRI) research in identifying altered brain structure and function in ataxia-telangiectasia, an autosomal recessive neurodegenerative disorder, is limited. Diffusion-weighted MRI were obtained from 11 ataxia telangiectasia patients (age range, 7-22 years; mean, 12 years) and 11 typically developing age-matched participants (age range, 8-23 years; mean, 13 years). ...
Wan Catherine Y CY Department of Neurology, Neuroimaging and Stroke Recovery Laboratories, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, - - 2014
Using a pre-post design, eleven chronic stroke patients with large left hemisphere lesions and nonfluent aphasia underwent diffusion tensor imaging and language testing before and after receiving 15weeks of an intensive intonation-based speech therapy. This treated patient group was compared to an untreated patient group (n=9) scanned twice over a ...
Lutgens Maurice M Department of Gastroenterology and Hepatology, University Medical Center Utrecht, The Netherlands; UCLA/VA Center for Outcomes Research and Education, Los Angeles, CA, USA. Electronic address: - - 2014
Surveillance guidelines for inflammatory bowel disease-associated colorectal cancer (IBD-CRC) are based on findings from retrospective studies. We aimed to create and validate a prediction rule to assist clinicians in identifying patients with IBD who are at low and high risk for CRC. We performed a retrospective case-control study of 2 ...
Anbar T S TS Dermatology Department, Al-Minya University, Al-Minya, - - 2014
Vitiligo has been classified clinically into segmental (SV) and non-segmental (NSV) and may also be associated with audiological abnormalities. In this study, we examined cochlear function in both ears of individuals with SV and NSV, including subjects with facial and non-facial lesions, and in SV patients with unilateral facial involvement. ...
Vollono C C Unit of Neurophysiopathology and Sleep Medicine, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Rome, - - 2014
Alternating hemiplegia of childhood (AHC) is a rare neurological disease characterized by recurrent paroxysmal attacks of hemiplegia. The aim of the study was to assess the recovery cycle of the somatosensory evoked potentials (SEPs) in a group of AHC patients. Seven AHC patients and 10 control age-matched subjects (CS) were ...
Yasuda Mitsuru M Department of Urology, Gifu University Hospital, Japan; Japanese Research Group for Urinary Tract Infection, Japan. Electronic address: - - 2014
We investigated the clinical effectiveness and safety of tazobactam/piperacillin (TAZ/PIPC) in a 1:8 ratio, a β-lactamase inhibitor with penicillin antibiotic, for the prevention of febrile infectious complication after prostate biopsy. Each patient received a single dose of TAZ/PIPC 4.5 g, 30 min before the biopsy in Group 1 or TAZ/PIPC 4.5 g twice, ...
Jiménez-Sousa Maria Angeles MA Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología. Instituto de Salud Carlos III, Majadahonda, Spain. Electronic address: - - 2014
To analyse whether mitochondrial DNA (mtDNA) haplogroups are associated with severe sepsis and mortality after major surgery. We performed a case-control study on 240 cardiac or abdominal surgery patients developing severe sepsis (Case-group) and 267 cardiac or abdominal surgery patients without severe sepsis and with systemic inflammatory response syndrome (SIRS, ...
Ferlazzo Edoardo - - 2014
Status epilepticus (SE) may occur in the setting of several internal or neurologic diseases. Anti-neutrophilic cytoplasmic antibodies (ANCA) are a group of Ig that may be observed in patients with different autoimmune disorders but are particularly associated with systemic vasculitis named ANCA-associated-vasculities (AAV). We herein report 3 patients with SE ...
Pastore Serena S Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo' and University of Trieste, Italy. - - 2014
Cryopyrin-associated periodic syndromes (CAPS) are a group of chronic, relapsing autoinflammatory disorders which may be complicated by systemic AA amyloidosis. The aim of our study was to evaluate serum amyloid protein A (SAA) level in CAPS patients treated with Interleukin-1beta (IL-1β) antagonist and to correlate its level with treatment response. ...
Kerkeni Mohsen M Laboratory of Biochemistry, LR12ES05, Faculty of Medicine, University of Monastir, Tunisia. Electronic address: - - 2014
There are limited data regarding the contribution of advanced glycation end products (AGEs) in the presence of coronary artery disease (CAD). We investigated whether serum pentosidine and Nε-carboxymethyllysine (CML) were related to the presence and the severity of CAD. 69 Tunisian patients with CAD (≥50% obstruction in≥1 coronary artery), 32 ...
Ninaber Maarten K MK Leiden University Medical Center, Department of Pulmonology, Leiden, The Netherlands. - - 2014
During cardiopulmonary exercise testing (CPET) compromised pulmonary vasculature in patients with systemic sclerosis (SSc) may lead to increases in pulmonary arterial pressures (PAP) and decreased oxygen uptake. We hypothesised that this may lead into a disproportional heart rate (HR) increase with a corresponding V'O2/HR breakpoint and relates to systolic PAP ...
Bostanc─▒ Vildan - - 2014
Objective: The aim of this study was to compare the periodontal status in patients with Familial Mediterranean Fever (FMF) and in those without this disease. Method and Materials: 84 subjects clinically diagnosed with FMF and 75 systemically healthy controls, matched by age and gender, were recruited. All FMF patients were ...
Hatano Masaru M Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan, - - 2014
Pulmonary arterial hypertension (PAH) trial has mostly enrolled patients with World Health Organization functional class (WHO FC) III or IV. However, PAH is rapidly progressive in nature even in patients with less severe forms at diagnosis. Following the recent studies in Western population, here we assessed the efficacy of bosentan ...
Abakay Ozlem O Department of Chest Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey, - - 2014
We aimed to investigate the correlation between red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and other inflammatory markers with pulmonary tuberculosis (PTB) severity. Seventy patients with active pulmonary tuberculosis were compared with 50 age-matched and gender-matched healthy controls. The mean age of ...
Cheng Huaibing H Center for Arrhythmia Diagnosis and Treatment, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 167 Beilishi Road, Beijing, 100037, People's Republic of - - 2014
To compare cardiovascular magnetic resonance (CMR) characteristics between arrhythmogenic right ventricular cardiomyopathy (ARVC) patients with syncope and without syncope and explore CMR parameters related with syncope. A consecutive series of 80 patients with ARVC were divided in two groups according to history of syncope prior to CMR examinations. The biventricular ...
Ehsaei Mohamadreza M Department of Neurosurgery, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Brain trauma is an important cause of mortality and disability among young people worldwide. One of the mechanisms of post-traumatic secondary brain damage is related to free radical release and oxidative stress (OS). OS is the consequence of an imbalance between pro-oxidants and antioxidants in favor of pro-oxidants. This imbalance ...
Cassler Nicole M NM Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, - - 2014
Asteatotic eczema (eczema craquelé, xerotic eczema) occurs most frequently in areas of dehydrated skin, most often during the winter months when decreased humidity results in increased water loss from the stratum corneum. We present 5 cases in which asteatotic eczema was found outside of its normal distribution, within desensitized skin ...
Celik Hacer H Department of Pulmonary, Ataturk Chest Disease and Chest Surgery Training and Research Hospital, Ankara, Turkey, - - 2014
Interleukin 8 (IL-8) is used to evaluate the severity of inflammation in the airways. The aim of this study was to evaluate patients with chronic obstructive pulmonary disease (COPD) for the presence of upper respiratory tract involvement by questioning patients regarding nasal symptoms and by measuring levels of IL-8 in ...
Kunihiro Yoshie Y Department of Radiology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan - - 2014
The combination of high-resolution computed tomography (HRCT) findings and serum markers would be of great value in diagnosing cytomegalovirus pneumonia (CMVP) and pneumocystis pneumonia (PCP) considering low invasiveness. To compare the HRCT findings of CMVP and PCP and to evaluate the differences in HRCT findings between patients diagnosed based on ...
Hu Shijun S Department of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, - - 2014
To report our experience with percardiac interventions for multiple congenital heart diseases in children. From April 2010 to December 2013, a total of 64 patients (33 males and 31 females), aged 4.38 ± 2.97 years, with multiple congenital heart diseases underwent attempted percardiac interventional procedures. The cohort included 34 ventricular ...
Freundlich Bruce B From the *University of Pennsylvania, Philadelphia, PA; †Antares Pharma, Inc, Ewing, NJ; and ‡Altoona Center for Clinical Research, Duncansville, - - 2014
A methotrexate autoinjector (MTXAI) was developed for self-administration of subcutaneous (SC) methotrexate by patients with rheumatoid arthritis (RA). The MTXAI circumvents the need for vials, needles, and syringes and may therefore improve dosing accuracy, handling risks, and patient adherence. The objective of this study was to evaluate actual human use ...
Aranda R M RM Department of Medicine, Hospital Universitario Puerto Real, School of Medicine, University of Cadiz, Cadiz, - - 2014
The relationship between the fluctuations of the anthropometric indices (AIs) and the prognosis of patients with incident heart failure (HF) in a population-based cohort is unknown. To assess the relationship between the fluctuations of the AIs, body mass index (BMI), waist hip ratio (WHR), and weight height ratio (WHeR) and ...
Hanada Isamu I Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, - - 2014
In Western countries, gene alterations involving the CRLF2-JAK signaling pathway are identified in approximately 50-60% of patients with Down syndrome-associated acute lymphoblastic leukemia (DS-ALL), and this pathway is considered a potential therapeutic target. The frequency of BTG1 deletions in DS-ALL is controversial. IKZF1 deletions, found in 20-30% of DS-ALL patients, ...
Pustina Dorian D Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, - - 2014
In temporal lobe epilepsy (TLE), the epileptogenic focus is focal and unilateral in the majority of patients. A key characteristic of focal TLE is the presence of subclinical epileptiform activity in both the ictal and contralateral "healthy" hemisphere. Such interictal activity is clinically important, as it may reflect the spread ...
Hasserjian Robert P RP Department of Pathology, Massachusetts General Hospital, Boston, - - 2014
It is controversial whether acute myeloid leukemia (AML) patients with 20-29% bone marrow (BM) blasts, formerly referred to as refractory anemia with excess blasts in transformation (RAEBT), should be considered AML or myelodysplastic syndrome (MDS) for the purposes of treatment and prognostication. We retrospectively studied 571 de novo AML in ...
Huang Duo D Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; Affiliated Hospital of North Sichuan Medical College & Medical Imaging Key Laboratory, Nanchong, Sichuan Province, - - 2014
 Patients with atrial fibrillation (AF) with CHA2 DS2 -VASc score of 1 (where CHA2 DS2 -VASc is CHA2 DS2 -Vascular disease, Age 65-74 years, Sex category) are recommended to receive antithrombotic therapy. Nonetheless, it remains unclear whether individual components that constitute CHA2 DS2 -VASc score contribute equally to the ischemic ...
Karadeniz Cem C Pediatric and Genetic Arrhythmia Center, Istanbul Medipol University Hospital, Istanbul, - - 2014
Radiofrequency (RF) catheter ablation in the septal arrhythmia substrates has an increased risk of irreversible atrioventricular block. Despite its safety profile, several studies reported a lower acute success rate and a higher recurrence rate with cryoablation of septal accessory pathways (APs) when compared to RF ablation. The aim of this ...
Patel N N Department of Pediatric Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, - - 2014
Breath testing is becoming an important diagnostic method to evaluate many disease states. In the light of rising healthcare costs, is important to develop a simple non-invasive tool to potentially identify paediatric patients who need endoscopy for suspected inflammatory bowel disease (IBD). To analyse exhaled volatile organic compounds (VOCs) and ...
Pawlak Krystyna K Department of Monitored Pharmacotherapy, Medical University, Bialystok, Poland. Electronic address: - - 2014
Patients with end-stage renal disease (ESRD) exhibit features of a hypercoagulable state, which may contribute to cardiovascular complications. Data from "in vitro" studies suggest that cell-free plasma lipids and lipoproteins may be capable to support thrombin generation. The aim of this study has been to establish the role of plasma ...
Kurtul Alparslan A Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey. Electronic address: - - 2014
The SYNTAX score (SXscore) is an anatomic scoring system based on coronary angiography (CA) that not only quantifies lesion severity and complexity but also predicts poor cardiovascular outcomes, including mortality, in patients with acute coronary syndromes (ACS). Recent studies have shown that platelet-to-lymphocyte ratio (PLR) is associated with worse outcomes ...
Martín Silvia - - 2014
Abstract Patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency need glucocorticoid (GC) therapy, which alters bone mineral metabolism. We analyze clinical and biochemical parameters and different polymorphisms of candidate genes associated with bone mineral density (BMD) in CAH patients. The CAH patients treated with GC and healthy controls ...
Mueller R B RB Division of Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, - - 2014
New American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria for the classification of rheumatoid arthritis (RA) have recently been proposed. The aim of this cohort study was to examine whether fulfilling these 2010 ACR/EULAR criteria at the first visit has an impact on the clinical course and on the ...
Elmac─▒ Ahmet Midhat AM Department of Pediatric Nephrology, Dr. Faruk Sukan Obstetric and Children's Hospital, Selcuklu, 42060, Konya, Turkey, - - 2014
The goal of this study was to investigate the metabolic etiology, clinical findings and medical treatment of children with urolithiasis in an endemic region of Turkey. We retrospectively analyzed the medical records of 742 (437 males, 305 females) children with urolithiasis. Physical examination results, serum biochemistry and urine metabolic evaluation, ...
Gray Kelly K Physiotherapy Department, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia, - - 2014
Congenital talipes equinovarus, or clubfoot, is a common pediatric orthopaedic condition of unknown origin. In many clubfoot clinical trials, interventions are assigned to a patient, but response to treatment is assessed separately in each foot. Trials commonly report x patients with y feet where y is greater than x (eg, ...
Cincin Altug A Department of Cardiology, Faculty of Medicine, Marmara University, Istanbul, Turkey, - - 2014
Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters. Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched ...
Chan Victoria V Department of Radiology, Level 2, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK, - - 2014
This study was designed to evaluate the role of a negative computed tomography angiogram (CTA) in patients who present with gastrointestinal (GI) hemorrhage. A review of all patients who had CTAs for GI hemorrhage over an 8-year period from January 2005 to December 2012 was performed. Data for patient demographics, ...
Holler Theresa - - 2014
BackgroundCompressive symptoms are common in patients with thyroid disease and are an accepted indication for thyroidectomy. The objective of this study was to evaluate the prevalence and severity of voice and swallowing complaints in pre-operative thyroidectomy patients and to compare these with thyroid volume, thyroid pathology and laryngopharyngeal reflux.MethodsA consecutive ...
Alam Shahinul S Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh, - - 2014
Nonalcoholic fatty liver disease (NAFLD) is considered to be a disease of obese individuals, yet lean patients are increasingly susceptible to have NAFLD. The aim of this study was to evaluate the profile of nonobese patients by comparing with obese NAFLD patients. We have included 465 patients of NAFLD after ...
Roquer Jaume J Servei de Neurologia, IMIM-Hospital del Mar, Passeig Marítim 25-29, 08003, Barcelona, Spain, - - 2014
To describe the clinical characteristics of first-ever ischemic stroke (IS) patients with prediabetes, and to compare them with diabetes mellitus (DM) and non-DM patient characteristics. Retrospective analysis of a prospective series of first-ever acute IS patients. Patients were classified as non-DM (HbA1c during admission <5.7 % and no previous evidence of ...
Qi Guang-Sheng GS Department of Respiratory Medicine, Shanghai Pudong New Area People's Hospital, Shanghai, - - 2014
The aim of our study was to evaluate volumetric capnography (VCap) in the differentiation between chronic obstructive pulmonary disease (COPD) patients and normal subjects. Thirty-nine healthy male volunteers and 60 male COPD patients were enrolled. Regression equations between VCap indices and age, weight, height, and tidal volume in healthy volunteers ...
< 6 7 8 9 10 11 12 13 14 15 16 >