Search Results
Results 501 - 550 of 14576
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van Lammeren Guus W GW University Medical Center Utrecht, Utrecht, the - - 2014
Time dependent trends in the incidence of cardiovascular disease have been reported in high-income countries. As atherosclerosis underlies the majority of cardiovascular diseases, we investigated temporal changes in the composition of atherosclerotic plaques removed from patients undergoing carotid endarterectomy. The Athero-Express study is an ongoing longitudinal vascular biobank study that ...
de Bourmont Sophie S aIntensive Care Unit, Timone University Hospital, Aix-Marseille University, Marseille bIntensive Care Unit, Sainte Musse Hospital, Toulon, - - 2014
Therapeutic hypothermia (TH) is part of the treatment strategy for comatose survivors of cardiac arrest (CA). The aim of our study was to evaluate the efficiency and the safety of a noninvasive and affordable cooling procedure applied to all types of CA in an ICU. This was a retrospective, observational, ...
Moazedi-Fuerst Florentine F Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria. - - 2014
As interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients is associated with increased mortality due to loss of diffusion capacity and pulmonary hypertension, regular screening for structural abnormalities of the lung is advised. In addition to standard radiological examination with computed x-ray tomography, ultrasound of the lung could allow ...
Chong Pin Fee PF Department of Pediatric Neurology, Fukuoka Children's Hospital, Fukuoka, Japan. Electronic address: - - 2014
Pontine tegmental cap dysplasia (PTCD) is a newly described brainstem malformation with distinct neuroimaging findings, characterized by a flattened ventral pons, cerebellar vermal hypoplasia and vaulted pontine tegmentum that forms a "caplike" or "beaklike" bulge projecting into the fourth ventricle. We describe a 3-month-old infant male who presented with typical ...
Leung Ling Yan LY Accident and Emergency Medicine Academic Unit, The Chinese University of Hong - - 2014
The present study aimed to investigate and compare plasma concentrations of miR-124-3p and miR-16 as diagnostic markers in acute stroke. miR-124-3p and miR-16 concentrations in 93 stroke patients were analyzed using real-time polymerase chain reaction. Primary outcome was the differentiation of hemorrhagic and ischemic stroke. Of 93 patients, 74 (79.6%) ...
Stamm Michael M Department of Radiology and Diagnostic Imaging, University of Alberta Hospital, Edmonton, Alberta, - - 2014
To assess ultrasound intrascan variability and the potential error rate of serial ultrasounds in the diagnosis of deep venous thrombosis in children. A retrospective cohort review of imaging results of children having at least 3 serial ultrasound examinations of the same region within a 2-month period. The results were interpreted ...
Sheikh Shahid S Division of Pulmonary Medicine, Department of Pediatrics, Nationwide Children's Hospital, ED 444 700 Children's Drive, Columbus, OH, 43205, USA, - - 2014
Osteoporosis associated with cystic fibrosis is becoming more important as the life expectancy of patients continues to improve. This study was done to determine the prevalence of osteoporosis and osteopenia in CF patients and to identify risk factors. We reviewed the medical charts of 103 adults and adolescents with Cystic ...
Hagenaars Julia C J P JC Dept. of Surgery, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands. Electronic address: - - 2014
The aim of this study was to estimate the seroprevalence of Q fever and prevalence of chronic Q fever in patients with abdominal aortic and/or iliac disease after the Q fever outbreak of 2007-2010 in the Netherlands. In November 2009, an ongoing screening program for Q fever was initiated. Patients ...
Migkos Michail P MP From the Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, - - 2014
Many studies have highlighted the hypolipidemic action of hydroxychloroquine (HCQ). We investigated the effect of HCQ on the lipid profile of patients with Sjögren syndrome (SS). The present retrospective observational study included 71 female patients with SS treated with HCQ. The levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL), ...
Abdulkader Rita R From the Research and Development Department, Department of Rheumatology, The Ipswich Hospital NHS Trust, Ipswich, - - 2014
Late-onset neutropenia (LON) is an adverse effect of rituximab (RTX) in hematological malignancies, a finding that was recently reported in rheumatoid arthritis (RA). The aim of our study was to estimate its incidence in RA. We retrospectively reviewed complete blood (cell) count of patients with RA who received RTX between ...
Jansa Pavel - - 2014
Pulmonary arterial hypertension (PAH) is a severe and progressive disease characterized by increased pulmonary vascular resistance, ultimately leading to right heart failure and death. Epidemiological data from national registries are growing worldwide, but are still unavailable in Eastern Europe. A PAH registry was initiated in January 2007 using a nationwide ...
Christensen L M LM Department of Neurology, Bispebjerg Hospital, Copenhagen University Hospitals, Copenhagen, - - 2014
Atrial fibrillation (AF) increases the risk of stroke fourfold and is associated with a poor clinical outcome. Despite work-up in compliance with guidelines, up to one-third of patients have cryptogenic stroke (CS). The prevalence of asymptomatic paroxysmal atrial fibrillation (PAF) in CS remains unknown. The SURPRISE project aimed at determining ...
Slimani Samy S Department of Medicine, Hadj Lakhdar University, Batna, Algeria, - - 2014
The aim of this study was to compare the epidemiology of rheumatoid arthritis (RA) in North Africa to that of Western countries. We have enrolled in a cross-sectional study all consecutive patients presenting with the diagnosis of RA according to the 1987 ACR criteria, and during a 5-month period, patients ...
Sunbul Murat M Marmara University Faculty of Medicine, Department of Cardiology, Istanbul, - - 2014
Arterial stiffness is associated with increased cardiovascular risk. Pulse wave velocity (PWV) and augmentation index (AIx) are non-invasive markers for assessment of arterial stiffness. Increased arterial stiffness is associated with atherosclerosis in patients with psoriasis. Previous studies have shown that high neutrophil-to-lymphocyte ratio (NLR) predicts poor cardiovascular outcome. The aim ...
Tsuru Yasuo Y Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, - - 2014
Objective diagnostic markers have not been in clinical use for psoriasis. In this study, we investigated the levels of miR-424 in hair roots and hair shafts in psoriatic patients, and evaluated the possibility that miR-424 can be a biomarker of the disease. A single hair root and five pieces of ...
Umbehr Martin H MH Department of Urology, University Hospital of Zurich, Zurich, - - 2014
Purpose: To investigate the association between the laterality of diagnostic prostate cancer-positive biopsy cores and definitive tumor stage on final pathology (organ-confined versus non-organ-confined). Patients and Methods: This is a retrospective analysis of 165 men after radical prostatectomy fulfilling our active surveillance criteria at the time of surgery. Nominal variables ...
Al-Kindi Hamood H Division of Cardiology, McGill University Health Centre, Montreal, Quebec, - - 2014
Urotensin II (UII) is a vasoactive peptide with various roles in cardiovascular physiology and pathophysiology. There is accumulating evidence implicating UII in atherosclerosis and coronary artery disease, making it an important target in acute coronary syndrome (ACS). In this study, we sought to determine the plasma levels of UII in ...
van Deursen Vincent M VM Department of Cardiology, University Medical Center Groningen, University of Groningen, The - - 2014
Elevated plasma concentrations of liver function tests are prevalent in patients with chronic heart failure (HF). Little is known about liver function in patients with acute HF. We aimed to assess the prevalence and prognostic value of serial measurements of liver function tests in patients admitted with acute decompensated HF. ...
Durmus Ahmet A Department of Hematology, Internal Medicine, Kanuni Training and Research Hospital, Trabzon, - - 2014
Objective: This study was designed to compare the oxidative stress parameters of patients with polycythemia vera (PV) to those of healthy volunteers and to investigate the probable relationship between vascular events and parameters of oxidative status such as total oxidative status (TOS), total antioxidant status, oxidative stress index (OSI) and ...
Stiermaier T T University of Leipzig-Heart Center, Department of Internal Medicine-Cardiology, Leipzig, - - 2014
Growth differentiation factor-15 (GDF-15), a stress responsive cytokine, has emerged as a marker of adverse outcome in various cardiovascular diseases. Since GDF-15 has not been evaluated in patients with Takotsubo cardiomyopathy (TTC), the present study sought to investigate the diagnostic and prognostic value in this patient cohort. A total of ...
Weeder Pepijn D PD Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands. Electronic address: - - 2014
The hemostatic profile of patients with liver diseases is frequently profoundly different from that of healthy individuals. These complex alterations lead to abnormal results from routine laboratory tests, but because of the nature of these assays, they fail to accurately represent the patient's hemostatic state. Nevertheless, based on abnormal laboratory ...
Fisichella Piero Marco PM Department of Surgery, Loyola University Medical Center, Maywood, Illinois. Electronic address: - - 2014
Patients with scleroderma and end-stage lung disease (ESLD) have a very high prevalence of gastroesophageal reflux disease (GERD). Because GERD has been associated with aspiration in those with ESLD, and because those with scleroderma are particularly prone to develop severe GERD, there is some concern that GERD may contribute to ...
Wolfkamp Simone Cs SC Simone CS Wolfkamp, Caroline Verseyden, Esther WM Vogels, Sander Meisner, Charlotte P Peters, Anje A te Velde, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, 1105 BK Amsterdam, The - - 2014
To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn's disease (CD). In this study, we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and ...
Ishihara Tomoaki T Tomoaki Ishihara, Department of Gastroenterology and Hepatology, Yokkaichi Digestive Disease Center, Komono, Mie 510-1232, - - 2014
To investigate the usefulness of branched-chain amino acids (BCAA) before transarterial chemoembolization (TACE) or radiofrequency ablation (RFA). We investigated the usefulness of pre-intervention with BCAAs by comparing patients treated with BCAAs at 12.45 g/d orally for at least 2 wk before TACE or RFA and those not receiving such pretreatment. ...
Carlsson Ingela K - - 2014
Cold sensitivity is a common complaint following hand injuries. Our aim was to investigate long-term self-reported cold sensitivity, and its predictors and the importance of sense of coherence (SOC), 8 years after a hand injury as well as in patients treated for Hand Arm Vibration Syndrome (HAVS) during the same ...
Capitanio B B Pediatric Dermatology, San Gallicano Dermatological Institute (IRCCS), Rome, - - 2014
Sebum plays a key role in the initiation of the acne lesions. Oxidized sebum lipids cause keratynocytes hyperproliferation and inflammatory cytokines release. Association between sebum oxidation and comedogenesis has been little investigated in comedonal acne. Evaluation of sebum oxidation parameters and levels of inflammatory cytokines (IL-1α) in patients with mild ...
Alp Hayrullah H Research Fellow, M.D, Necmettin Erbakan University, Meram School of Medicine Hospital, Department of Pediatric - - 2014
Simple electrocardiographic markers have been used to evaluate conduction times. Acute rheumatic fever (ARF) is an autoimmune disease which affects these conduction times. In this prospective long-term follow-up study, we evaluated QT, QTc and P-wave dispersions in the children with acute rheumatic fever (ARF) and chronic rheumatic heart disease (CRHD). ...
Nakajima Makoto M Department of Neurology, Stroke Center, Saiseikai Kumamoto Hospital, Kumamoto, Japan. Electronic address: - - 2014
Nontraumatic convexal subarachnoid hemorrhage (cSAH) rarely occurs subsequent to acute ischemic stroke. The incidence, clinical background characteristics, and outcomes in acute ischemic stroke patients with cSAH were investigated. Our stroke center database was reviewed to identify patients with acute ischemic stroke/transient ischemic attack (TIA) who demonstrated acute cSAH within 14 days ...
Mrad Meriem M Faculté des Science de Tunis, Université Tunis el Manar, El Manar, Tunisie; Laboratoire de Biologie Moléculaire, Service d'Hématologie, Hôpital Militaire Principal d'Instruction de Tunis, Montfleury, - - 2014
Retinal vein occlusion (RVO) is the second most common cause of vision loss because of retinal vascular disease. There are 2 types of RVO: branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO). The pathogenesis of RVO is multifactorial. The role of factor V Leiden (FVL) and prothrombin ...
Power Stephen P SP Department of Neurology, Cork University Hospital, Wilton, Cork, - - 2014
Objective: To determine the proportion of patients who would have an unsuccessful lumbar puncture due to commonly used lumbar puncture needles being too short. Design & Methods: 300 consecutive adults (age 16-99, mean age 56) who underwent abdominal CT over a 6 month period were identified. The distance from the ...
Del-Rio-Vellosillo M M Department of Anesthesia, University Hospital Virgen de la Arrixaca, Murcia, - - 2014
Anaesthetists need to know the different causes of persistent headache or a change in level of consciousness following epidural analgesia for labour. Failure to recognise these neurological complications can lead to delayed diagnoses, with subsequent serious implications. We present a patient who was re-admitted for postural headache resulting from an ...
Hong J S JS Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea; Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, - - 2014
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in women of childbearing-age. Although PCOS has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of PCOS patients in Asia. The goal of this study is to elucidate the dermatological characteristics and metabolic ...
Brambatti Michela M Population Health Research Institute, McMaster University, Hamilton, ON, Canada; Università Politecnica delle Marche, Ancona, - - 2014
Among patients with implantable pacemakers and defibrillators, sub-clinical atrial fibrillation (SCAF) is associated with an increased risk of stroke; however, there is limited understanding of their temporal relationship. The ASSERT trial enrolled 2580 pacemaker and defibrillator patients ≥ 65 years old, with a history of hypertension, but without a history ...
Hu Kuang-Chun KC Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan; Healthy Evaluation Center, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medicine, Nursing and Management College, Taipei, Taiwan; Graduate Institute of Clinical Medicine, National Taiwan University College of - - 2014
The role of clinical symptoms, trans-abdominal ultrasound scan (USS), and liver function tests (LFTs) in evaluating common bile duct (CBD) stones in patients suspected to have pancreatobiliary disease has been studied. However, it is unclear whether these predictive models are useful in different age cohorts. To investigate the clinical presentations ...
Vuga Louis J LJ University of Pittsburgh, Medicine, Pittsburgh, Pennsylvania, United States ; - - 2014
Rationale: C-X-C motif chemokine 13 (CXCL13) mediates B-cell trafficking and is increased, proportionately to disease activity, in many antibody-mediated syndromes. Dysregulated B-cells have recently been implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis. Objective: To determine if CXCL13 is associated with IPF progression. Methods: CXCL13 was measured in lungs by DNA ...
Rather Tanveer A TA Department of Nuclear Medicine, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, - - 2014
Background: Dyshormonogenetic goiter refers to familial goiters owing to an inherited defect in the metabolism of thyroid hormones. Methods: 19 patients with clinical and biochemically proven hypothyroidism (low T3, FT4 and high TSH) were recruited for the study. All patients were subjected to (i) ultrasound of the neck to rule ...
Aldajani Nader N Department of Otorhinolaryngology, King Abdulaziz Medical City, Riyadh, Saudi Arabia, - - 2014
The objective of this study is to investigate the effects of IDDM on the function of the auditory pathway from the cochlea to the auditory cortex in child patients. Totally, 140 ears of 70 children with IDDM and 60 ears of 30 age and gender-matched healthy controls were included in ...
Ronot Maxime M Department of Radiology, Beaujon University Hospitals Paris Nord Val de Seine, 100 Bd du Général Leclerc, 92110, Clichy, France, - - 2014
To assess the value of the liver and spleen viscoelastic parameters at multifrequency MR elastography to determine the degree of portal hypertension and presence of high-risk oesophageal varices in patients with cirrhosis. From January to September 2012, 36 consecutive patients with cirrhosis evaluated for transplantation were prospectively included. All patients ...
Severens M M Sint Maartenskliniek Nijmegen, Research Department, The Netherlands; Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, The Netherlands. Electronic address: - - 2014
Brain-computer interfaces (BCI) tested in patients often are gaze-dependent, while these intended users could possibly lose the ability to focus their gaze. Therefore, a visual and a tactile gaze-independent spelling system were investigated. Five patients with amyotrophic lateral sclerosis (ALS) tested a visual Hex-o-Spell and a tactile speller. Six healthy ...
Prejbisz Aleksander A Department of Hypertension, Institute of Cardiology, Warsaw, - - 2014
We addressed a question if there is a relationship between severity of newly diagnosed obstructive sleep apnea (OSA) and markers of cardiovascular alterations in middle-aged untreated hypertensive patients. In 121 consecutive patients with never-treated essential hypertension (mean age 35.9±10.1 years; 97 men and 24 women) evaluation of office and ambulatory ...
Kariya S S Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, - - 2014
Background: A close relationship between upper and lower respiratory tract diseases has been reported. However, little is known about pulmonary function in patients with upper respiratory tract diseases. Methods: Pulmonary function was measured in: 68 patients with chronic rhinosinusitis without nasal polyps, 135 patients with chronic rhinosinusitis with nasal polyps, ...
Derks Terry G J TG Section of Metabolic Diseases, University Medical Center Groningen, University of Groningen, 9700, RB, Groningen, The Netherlands, - - 2014
The objective of this study was to test whether macromolecule oxidative damage and altered enzymatic antioxidative defenses occur in patients with medium-chain acyl coenzyme A dehydrogenase (MCAD) deficiency. We performed a cross-sectional observational study of in vivo parameters of lipid and protein oxidative damage and antioxidant defenses in asymptomatic, nonstressed, ...
Vyskocilova Klaudia K 1st Department of Internal Medicine - Cardioangiology, St. Anne's University Hospital in Brno, International Clinical Research Center and Faculty of Medicine, Masaryk University, Brno, Czech - - 2014
Liver pathology caused by cardiac dysfunction is relatively well recognized, however, its clinical importance has not been fully evaluated. The aim of this study was to assess the prevalence of liver function tests (LFTs) abnormalities and to identify associated factors mediating hepatic impairment in patients with acute heart failure (AHF). ...
Matsuda Yayoi Y Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, - - 2014
Surgical treatment of pheochromocytoma is associated with a high risk of hemodynamic instability. To reduce the risk of perioperative complications, adequate medical treatment to normalize blood pressure and restore blood volume is required. Accurate evaluation of the circulating blood volume (CBV) in perioperative patients with pheochromocytoma is clinically important. In ...
Amaro Carmen Regina Petean Ruiz CR Urinary Lithiasis Metabolism Service, Medical School of Botucatu - UNESP, Botucatu, SP, 18618-970, Brazil, - - 2014
The objective of this study was to evaluate the prevalence of urinary metabolic abnormalities in patients with urolithiasis and their potential risk factors. A total of 905 stone patients were evaluated in a prospective trial from February 2000 to January 2012. Inclusion criteria were as follows: history and/or imaging tests ...
Marsovszky László L Department of Ophthalmology, Semmelweis University Budapest, Mária u. 39, 1085, Budapest, Hungary, - - 2014
The recently developed confocal cornea microscopy offers the opportunity to examine pathologies of the cornea and to gain insight into the activity of innate immunity. We aimed to investigate the corneal epithelial and Langerhans cell (LC) densities along with dry eye parameters in primary open-angle glaucoma (POAG) subjects, treated with ...
Thandassery Ragesh Babu RB Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, - - 2014
Hypotension and intestinal mucosal ischemia lead to bacterial translocation from the gut lumen into systemic circulation. The purpose of this study was to determine the strength of association between different types of organ failure (OF): hypotension (cardiovascular system failure), renal failure, respiratory failure, CNS failure and coagulopathy in the first ...
Emad Yasser Y Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Cairo, Egypt, - - 2014
This study aimed to determine the frequency of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibodies in a cohort of patients with palindromic rheumatism (PR) and to find determinants for progression to rheumatoid arthritis (RA). All new cases of PR (n = 90) were included prospectively and followed up for 1 year, ...
Jin Meiling M State Key Laboratory of Kidney Disease, Institute of Nephrology, Chinese PLA General Hospital, Beijing 100853, China; Medical College, Nankai University, Tianjin 300071, - - 2014
To assess the effectiveness of supine/standing urinalysis for differential diagnosis of left renal vein entrapment syndrome (LRVES) combined with or without glomerulopathy. The enrolled patients with abnormal urinalysis and LRVES demonstrated by Doppler sonography were guided to perform a supine/standing urinalysis. Fifty-two patients were enrolled. Most of them were adolescents ...
Cotter José J Gastroenterology Department, Centro Hospitalar do Alto Ave, Guimarães, Portugal; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal; ICVS/3B's, PT Government Associate Laboratory, 4710-057 Guimarães, Braga, Portugal. Electronic address: - - 2014
Small bowel capsule endoscopy (SBCE) may detect proximal small bowel lesions that have been previously missed by ileocolonoscopy and small bowel imaging in patients with known ileal and/or colonic Crohn's disease (CD). We aimed to evaluate whether the therapeutic management is influenced by SBCE findings. Retrospective single center study. Inclusion ...
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