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Suganthi Lakshmanan L Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai, 600036, Tamilnadu, India, - - 2014
Takayasu's arteritis disease (TA) remains a rarely studied chronic inflammatory disease. Our objective is to analyze peripheral pulse using photoplethysmography (PPG) as a new assessment method for diagnosing TA. So far no literature reports detailed morphological analysis of TA PPG signals. PPG signals of twenty normal and twenty TA patients ...
Sliwa Thamer T 5th Department of Internal Medicine - Oncology/Hematology, Hospital Hietzing Vienna, - - 2014
The Notch signaling pathway is a cell program that is active during early development of multicellular organisms and is required for the formation of basic structures in the growing embryo. Scientific evidence which has accumulated during the last years clearly indicates that aberrant pathway activation may also be critical for ...
Pungavkar Sona S Dr. Balabhai Nanavati Hospital, Vile Parle (west), Mumbai 400 056, India. Electronic address: - - 2013
We present three cases of T1 hyperintense signal in the MRI scans of the brains of pregnant patients who were administered magnesium sulphate intramuscularly for control of hypertension during eclampsia. The increase in signal is symmetric and is seen in the globus pallidi of these patients. We postulate it to ...
Fujinami Kaoru - - 2013
PURPOSE To characterise subtypes of fundus autofluorescence (AF), the progression of retinal atrophy and correlate these findings with genotype in Stargardt Disease. METHODS Full clinical examination and AF imaging was undertaken in 68 patients with Stargardt Disease. The baseline data were compared with those at follow-up. Patients were classified into ...
Sant'ana Petterle Giovanna - - 2013
The aim of the present study was to demonstrate the utility of ultrasound to show subclinical feet disease in RA. The foot joints (talocrural, talocalcaneal, talonavicular, naviculocuneiform, calcaneocuboid, 5th tarsometatarsal and 1st to 5th metatarsophalangeal [MTP] joints) of 50 healthy subjects and 50 RA patients, with asymptomatic feet, were compared ...
Flanagan D - - 2013
To identify features of BOLD signal change associated with interictal epileptiform discharges (IEDs) in a heterogeneous group of focal epilepsy patients. EEG/fMRI studies in 27 focal epilepsy patients were reviewed with attention given to the extent and location of the IED and the resulting pattern of BOLD signal change. Second ...
Ueda Taishi - - 2013
Mild cognitive impairment (MCI) patients and healthy people were classified by using a "power variance function (PVF)", namely, an index of electroencephalography (EEG) proposed in a previous report. PVF is defined by calculating variance of the power variability of an EEG signal at each frequency of the signal using wavelet ...
Ao Di - - 2013
An innovative method to quantitatively assess the motor function of upper extremities for post-stroke patients is proposed. A post-stroke patient and a normal subject were recruited to conduct a special performance of voluntary elbow flexion and extension by following a sinusoidal trajectory from 30° to 90° at 6 different peak ...
Maffeo Elisa - - 2013
Chronic acquired hepatocerebral degeneration (CAHD) is a rare neurological disorder of cirrhotic patients, characterized by parkinsonism and cognitive impairment. A T1 hyperintensity on the globus pallidum due to an accumulation of manganese (Mn) is found in these patients. The aim of the study was to investigate CAHD, Mn and the ...
Gärtner Miriam - - 2013
Background: Sonography is a sensitive tool for evaluating synovitis in rheumatoid arthritis (RA) compared with clinical assessment. However, differences between these assessments may depend on how "joint activity" is defined. Therefore, we compared clinically vs. sonographically active joints in RA by different sonographic definitions. Methods: Sonographic assessment of finger and ...
Marshall Helen - - 2013
PURPOSE: Lung pO2 mapping with (3) He MRI assumes that the sources of signal decay with time during a breath-hold are radiofrequency depolarization and oxygen-dependent T1 relaxation, but the method is sensitive to other sources of spatio-temporal signal change such as diffusion. The purpose of this work was to assess ...
Eide Per Kristian - - 2013
ABSTRACT: BACKGROUND: In an attempt to characterize the intracranial pressure-volume compensatory reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the ICP (P) level (RAP) has been applied in the surveillance of neurosurgical patients. However, as the ICP level may become altered by electrostatic discharges, human ...
Han Chun-Xiao CX Tianjin Key Laboratory of Information Sensing & Intelligent Control, Tianjin University of Technology and Education, Tianjin, 300222 China ; Institute of Semiconductors, Chinese Academy of Sciences, Beijing, 100083 - - 2013
The objective of the present study was to investigate brain activity abnormalities in the early stage of Parkinson's disease (PD). To achieve this goal, eyes-closed resting state electroencephalography (EEG) signals were recorded from 15 early-stage PD patients and 15 age-matched healthy controls. The AR Burg method and the wavelet packet ...
Kerasnoudis Antonios - - 2013
BACKGROUND AND PURPOSE: The detection of microembolic signals in transcranial-Doppler monitoring is associated with a higher stroke risk. We investigated the correlation between the frequency of microembolic signals and the efficacy of the antiplatelet therapy in patients with a recent symptomatic carotid-artery stenosis. SUBJECTS AND METHODS: Thirty-two patients (mean age: ...
Han Yong-Hee - - 2012
OBJECTIVE: There have been various studies showing increased iron levels in parkinsonian disorders. The purpose of this study was to demonstrate topographical differences of brain iron deposition between progressive supranuclear palsy (PSP) and the parkinsonian variant of multiple system atrophy (MSA-p) with SWI images. METHODS: A total of 11 patients ...
Tripoliti Evanthia E - - 2012
The aim of this study is to detect freezing of gait (FoG) events in patients suffering from Parkinson's disease (PD) using signals received from wearable sensors (six accelerometers and two gyroscopes) placed on the patients' body. For this purpose, an automated methodology has been developed which consists of four stages. ...
Ishikawa Kazuhiro - - 2012
INTRODUCTION: With reported characteristic MR features, it is difficult to differentiate vestibular schwannomas (VSs) from cerebellopontine angle (CPA) meningiomas (CPAMs) in some cases. This study aimed to evaluate vestibular signal intensity changes in patients with VS and those with CPAM on three-dimensional fast imaging employing steady-state acquisition (3D-FIESTA), and to ...
Kibayashi Kazuhiko - - 2012
ABSTRACT: We analyzed forensic autopsy findings of 66 consecutive patients with fatal closed head injury who survived up to 48 days after trauma to ascertain the causal factors and the time course of development of posttraumatic pituitary lesions. Pituitary lesions were identified in 27 patients. In patients with pituitary lesions, ...
Handojoseno A M Ardi - - 2012
Freezing of Gait (FOG) is one of the most disabling gait disturbances of Parkinson's disease (PD). The experience has often been described as "feeling like their feet have been glued to the floor while trying to walk" and as such it is a common cause of falling in PD patients. ...
Dai Zunyan - - 2012
Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC). Patients with ALK rearrangements do not respond to EGFR-specific tyrosine kinase inhibitors (TKIs); however, they do benefit from small molecule inhibitors targeting ALK. In this study, fluorescence in ...
Rabbani Hossein - - 2011
Ischemic heart disease is one of the common fatal diseases in advanced countries. Because signal perturbation in healthy people is less than signal perturbation in patients, entropy measure can be used as an appropriate feature for ischemia detection. Four entropy-based methods comprising of using electrocardiogram (ECG) signal directly, wavelet sub-bands ...
Protogerou G - - 2011
Amyotrophic lateral sclerosis (ALS) is characterized by progressive upper and lower motor neuron degeneration. A hyperintense signal on T2-weighted images along the corticospinal tract has been reported in patients with confirmed ALS. However, the specificity of this finding is under consideration, since it is also identified in healthy controls. Moreover, ...
Sipahi Savas - - 2011
BACKGROUND: Bioimpedance spectroscopy (BIS) is used to assess volume status in peritoneal dialysis (PD) patients. However, it is proposed that it may be troubling in patients with abnormal fluid distribution and body geometry. It is not clear whether having an empty abdomen or not interferes with the BIS results and ...
Gürkov Robert - - 2011
Our objective is to determine whether the degree of endolymphatic hydrops as it is detected in vivo in patients with definite Meniere's disease correlates with audiovestibular function. In this prospective study, 37 patients with definite Meniere's disease according to AAO-HNS criteria were included. Intratympanic contrast enhanced temporal bone MRI was ...
da Silva Renata Marques Gonçalves - - 2011
Primary Pigmented Nodular Adrenocortical Disease (PPNAD) is a rare form of bilateral adrenocortical hyperplasia that is inherited in an autosomal dominant manner and leads to ACTH-independent Cushing's syndrome (CS). PPNAD may be isolated or associated with Carney Complex (CNC). For the diagnosis of PPNAD and CNC, in addition to the ...
Akin Korhan Esra - - 2011
: The aim of this study was to compare semiexperimentally the pulse oximetry values obtained from a finger on restrained or unrestrained sides of the body. : The pulse oximeter provides a noninvasive measurement of the oxygen saturation of hemoglobin in arterial blood. One of the procedures most frequently applied ...
Miyachi Kiyomitsu - - 2011
Amantadine is not thought to be effective for the treatment of swine-origin influenza virus (S-OIV) based on an analysis of genetic sequences of the M2 protein. However, the actual clinical efficacy of amantadine has not been well documented. Here, we were able to compare the efficacies of amantadine and neuraminidase ...
Maruo Tomoyuki - - 2011
Patients with Parkinson's disease (PD) reportedly show deficits in sensory processing in addition to motor symptoms. However, little is known about the effects of bilateral deep brain stimulation of the subthalamic nucleus (STN-DBS) on temperature sensation as measured by quantitative sensory testing (QST). This study was designed to quantitatively evaluate ...
Pfaffenberger N - - 2011
Pfaffenberger N, Gutweniger S, Kopp M, Seeber B, Stürz K, Berger T, Günther V. Impaired body image in patients with multiple sclerosis. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2010.01460.x. © 2011 John Wiley & Sons A/S. Objective -  Despite the growing research on body image disturbances in chronically ill patients, reports of such ...
Neuman Michael - - 2011
We looked at the vital signs of temperature and heart rate in the first two tutorials of this series, and this time, we look at a third vital sign: breathing rate. When I was in clinical training, this vital sign was often either overlooked or given superficial treatment. By observing ...
Ucok Kagan - - 2011
Objective Obstructive Sleep Apnea Syndrome (OSAS) is a common sleep-related breathing disorder. Associations among Apnea-Hypopnea Index (AHI), Resting Metabolic Rate (RMR), body habitus differences, and otorhinolaryngologic abnormality may clarify the characteristics of patients with OSAS. In order to test this hypothesis, we aimed to compare the RMR, Modified Mallampati Scores ...
Taghavi Mahsa M Department of Psychiatry and Behavioral Sciences, Shiraz University of Medical Sciences, Shiraz - - 2011
Objectives: Diagnosis of the psychiatric diseases is a bit challenging at the first interview due to this fact that qualitative criteria are not as accurate as quantitative ones. Here, the objective is to classify schizophrenic patients from the healthy subject using a quantitative index elicited from their electroencephalogram (EEG) signals. ...
Huber Benedikt M - - 2010
 Glucocorticoids (GCs) are often used for the treatment of rheumatic disorders. However, doses are prescribed, which may suppress the hypothalamic-pituitary-adrenal (HPA) axis. After GC withdrawal, recovery of the HPA axis may be delayed putting the patient at risk for adrenal insufficiency. We assessed adrenal function and factors influencing adrenal responsiveness ...
Kawai Naoki - - 2011
The clinical symptoms and effectiveness of neuraminidase inhibitors (NAI) have not been adequately compared among pandemic H1N1 2009 patients, seasonal H1N1 patients, and patients with H1N1 with the H275Y mutation. The data of 68 seasonal H1N1 patients in 2007-2008, 193 seasonal H1N1 patients in 2008-2009, and 361 pandemic H1N1 2009 ...
Vallette Sophie - - 2010
Oral estrogens reduce GH-induced IGF-1 production and preliminary studies have shown that adjuvant estroprogestin (EP) therapy with octreotide LAR may control disease activity in some female patients who are partially responsive to octreotide LAR. Our aim was to verify if EP alone or in combination with octreotide LAR can achieve ...
Acharya Shrikrishna V - - 2010
Pituitary radiotherapy (RT) is an effective second-line treatment for paediatric Cushing's disease (CD). We report long-term efficacy and anterior pituitary function in a cohort of paediatric CD patients treated with RT. Between 1988 and 2008, from our cohort of 48 paediatric CD patients, eight paediatric CD patients (5 males and ...
Fukui Makoto - - 2010
To investigate the relationship between salivary stress markers and mental stress states in patients complaining of oral malodour. The utility of the salivary stress markers in assessment of mental conditions of those patients was also investigated. The study population included 74 patients, aged 20-59 years, who complained of oral malodour ...
El-Bilbeisi Hazem - - 2010
We present the first reported case of a craniopharyngioma as a second primary tumor in a patient with acromegaly due to a growth hormone (GH)-secreting pituitary adenoma. The patient was lost for follow-up for 18 years after trans-sphenoidal pituitary surgery for a GH-secreting pituitary adenoma. She presented with headaches and ...
Farholt Stense - - 2011
Prader-Willi syndrome (PWS) is a genetic disease associated with hypogonadism and partial GH insufficiency, possibly explained in part by a hypothalamic dysfunction. Partial insufficiency of the hypothalamic-pituitary-adrenal (HPA) axis has recently been suggested. The objective of the study was to further explore the HPA axis in PWS by use of ...
Mendiratta-Lala Mishal - - 2011
To evaluate the use of radiofrequency (RF) ablation as a primary treatment for symptomatic primary functional adrenal neoplasms and determine the efficacy of treatment with use of clinical and biochemical follow-up. After obtaining institutional review board approval, the authors retrospectively evaluated images and medical records from 13 consecutive patients with ...
Verrua E - - 2011
The cutoff value of nadir GH after an oral glucose tolerance test (OGTT) used to define disease remission in acromegaly is higher than that observed in healthy subjects. However, it is uncertain whether the impaired GH inhibition might be related to subtle abnormalities of GH secretion or to functional and/or ...
Imperiale Alessio - - 2011
The aim of this preliminary study is to characterize by ¹H high-resolution magic angle spinning NMR spectroscopy (HRMAS) the metabolic content of intact biopsy samples obtained from 12 patients suffering from neuroblastoma (NB). The biochemical NB profile was first compared to normal adrenal medulla. In a second step, the relationship ...
Möller-Goede Diane L - - 2011
To assess frequency, symptoms and outcome of pituitary apoplexy (PA) among pituitary adenoma patients, to gain better insight into risk factors for bleeding into pituitary adenoma and to estimate the sequelae of PA by means of a matched control group. By reviewing charts of 574 patients with pituitary adenoma, we ...
Costa-Barbosa F A - - 2011
Although much is known about the increased levels of the 21-hydroxylase substrates 17-hydroxyprogesterone (17OHP) and 21-deoxycortisol (21DF) - the biochemical markers of all forms of 21-hydroxylase deficiency (21OHD), only limited information is available on the zona fasciculata (ZF) products distal to the enzymatic block: 11-deoxycortisol (S), 11-deoxycorticosterone (DOC), and corticosterone ...
Leboulleux S - - 2011
To make the specificity of fluorodesoxyglucose ((18)FDG) positron emission tomography (PET) precise, in the follow-up of patients with adrenal cancer. This single centre retrospective study assessed the frequency and outcome of (18)FDG uptake in the remaining adrenal glands after adrenalectomy for adrenocortical carcinoma (ACC) or malignant phaeochromocytoma (PH). Two hundred ...
Zada Gabriel - - 2010
Growth patterns of pituitary adenomas have been observed to vary by histopathological subtype. The authors aimed to analyze variations in the patterns of extrasellar extension of nonfunctional macroadenomas (NFMAs) and growth hormone (GH)-secreting macroadenomas. A retrospective review was conducted of data obtained in 75 patients who underwent transsphenoidal operations for ...
O'Neill Christine J - - 2010
INTRODUCTION: The number of incidentally discovered adrenal lesions is increasing due to the widespread use of abdominal imaging. Although most incidentalomas are benign, larger suspicious lesions will require adrenalectomy. The aim of this study is to determine the risk of malignancy in patients undergoing surgery for adrenal incidentaloma; and to ...
Wang Liang-Jen - - 2011
Abstract Objectives. The purposes of this study were to determine whether salivary levels of dehydroepiandrosterone (DHEA) and cortisol are associated with attention deficit hyperactivity disorder (ADHD) or correlated with performance on the Continuous Performance Test (CPT). Methods. Fifty ADHD patients and 50 age- and gender-matched controls aged between 6 and ...
Salluh Jorge I F - - 2010
Our aim was to review the literature on the prevalence and impact of critical-illness related corticosteroid insufficiency (CIRCI) on the outcomes of patients with severe community-acquired pneumonia (CAP). We reviewed Cochrane, Medline, and CINAHL databases (through July 2008) to identify studies evaluating the adrenal function in severe CAP. Main data ...
Rotman-Pikielny P - - 2010
Hypothalamic-pituitary-adrenal (HPA) axis insufficiency is the most common endocrine disorder in patients with antiphospholipid syndrome (APS). Primary adrenal failure because of venous thrombosis and/or adrenal haemorrhage is the leading diagnosis, while another possible mechanism is autoimmune adrenal failure. Prospective evaluation of the HPA axis in patients with APS has not ...
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