Search Results
Results 201 - 250 of 2072
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Miyara Tetsuhiro - - 2011
Our aim was to investigate the incidence and characteristics of bronchial diverticula using multidetector-row computed tomography (MDCT) and to evaluate their association with smoking status. Two radiologists retrospectively reviewed MDCT scans obtained between December 2007 and February 2008 with a 4-row or a 64-row MDCT scanner for 1122 consecutive patients. ...
Anari Hassan - - 2011
Ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. This study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. From March 2008 to March 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 ...
Kann P H - - 2011
Background & Aim Patients with MEN1 often have low bone mineral density (BMD) attributed to primary hyperparathyroidism (pHPT). However, in MEN1 patients other endocrine dysfunctions and conditions such as hypercortisolism, hypogonadism and growth hormone deficiency due to pituitary manifestation, and surgery on the upper gastrointestinal tract may affect BMD. Subjects ...
Shimizu Masaki - - 2011
Pulmonary arterial hypertension (PAH) when associated with systemic sclerosis (SSc) (SSc-PAH) is one of the leading causes of mortality and is found in 10-15% of adult patients with SSc. The ET receptor antagonist bosentan has been shown to be effective in the treatment of adult patients with SSc-PAH. Furthermore, it ...
Nersita Roberto - - 2011
Objective:  Vascular Endothelial Growth Factor D (VEGF-D) has been identified as one of the lymphangiogenic growth factors involved in metastatic diffusion. The aim of this study is to evaluate the serum VEGF-D levels in patients with differentiated thyroid cancer at different conditions of disease. Design and Patients: We studied prospectively ...
Pelisek Jaroslav - - 2011
Little is known about the effect of chronic kidney disease (CKD) on plaque morphology in cerebral vessels. We therefore analyzed plaque composition and metabolic and chemical parameters with regard to clinical outcome in patients with advanced carotid artery stenosis (>70%) and normal or impaired renal function. Carotid endarterectomy plaques were ...
Abdel-Razic Moheb M - - 2011
Objective: This study aims to provide further insight into the phenotypic heterogeneity of Klinefelter syndrome (KS) by presenting clinical, hormonal, and genetic data from a large series of Egyptian infertile patients with KS. Patients and Methods: A retrospective case series of KS patients was studied over the period from January ...
Pappa Theodora - - 2011
Eur J Clin Invest 2011 ABSTRACT: Background  Acromegaly is well known to induce hypertrophic and hyperplastic changes in various organs and is commonly accompanied by arterial hypertension. In our study, we assess the adrenal morphology and function in a series of patients with acromegaly and possible associations with the activity ...
McQuade Christine - - 2011
Background: Thyroid hormones have profound effect on the heart and peripheral vasculature. Hypothyroidism is associated with an increase in a number of coronary heart disease (CHD) risk factors including dyslipidemia, hypertension, and elevated levels of homocysteine. Our objective was to assess the effects of hypothyroidism (thyroid-stimulating hormone [TSH]: >10 μU/mL), moderate ...
Wang Chen-Chi - - 2011
Background: Preoperative vocal fold paralysis (VFP) is thought to be rare in patients with benign thyroid disease (BTD). In contrast with cases of malignancy, in which the recurrent laryngeal nerve (RLN) should be severed, in patients with BTD and VFP the RLN can be preserved without threatening patients' lives. This ...
Tzanela M - - 2011
Background: Adrenal incidentalomas (AI) is a common clinical problem. Subtle hormonal abnormalities, are present in a substantial proportion of patients. BCL1 gene polymorphism of the glucocorticoid receptor (GR) is associated with increased sensitivity to glucocorticoid action. The genotype-phenotype associations of this polymomorphism in patients presenting with AI has not been ...
Prichard Ruth S - - 2011
Permanent hypoparathyroidism is a well-recognized complication of total thyroidectomy, and a commonly reported clinical indicator of that procedure. However, a small number of patients still require ongoing calcium supplementation post-operatively in order to avoid the symptoms of hypocalcaemia, despite a normal serum parathyroid hormone level. The aim of this study ...
Akbulut Sami - - 2011
This purpose of this article is to document ectopic bone formation (EBF) and extramedullary hematopoiesis (EMH) in thyroidectomy specimens. We present a case of multinodular goiter with EMH and EBF, as well as a literature review of studies published in the English language on EMH and/or bone formation in the ...
Banaka I - - 2011
To determine thyroid vascularity in healthy subjects and patients with autoimmune thyroid disease (AITD), and assess its sensitivity and specificity for the diagnosis of AITD. High-sensitivity color flow Doppler sonography (HSCFDS) was used to estimate the thyroid intraparenchymal vascularity in 31 euthyroid patients with Hashimoto's thyroiditis (HD), 33 hypothyroid patients ...
Sedighi Omid - - 2011
Introduction. Prevalence of hypertension is high in hemodialysis patients. Increase of intracellular calcium due to hyperparathyroidism is one of probable factors for hypertension in hemodialysis patients. In this study, the relationship between serum parathyroid hormone (PTH) level and severity of hypertension in hemodialysis patients was investigated. Materials and Methods. In ...
Krishnan Sandeep Kumar - - 2011
In elderly patients with established atrial fibrillation (AF) who are receiving thyroid replacement, regular testing for thyroid function is often not performed, placing the patient at risk for iatrogenic hyperthyroidism. Of 215 patients followed in an anticoagulation clinic, 41 were receiving thyroid replacement and 15 of these were found to ...
Kowalczuk-Wieteska Anetta - - 2011
Thyroid hormones are essential for the correct functioning of the entire body. Diagnosis of thyroid disorders in patients after heart transplant in the early post-operative period and the implementation of correct treatment may prevent life-threatening complications. The aim of the study was to determine whether the complicated postoperative course (ie, ...
Bechtold Susanne - - 2011
At final height, somatic maturity has not been reached yet. We investigated bone and body composition in patients, who completed pediatric growth hormone (GH) treatment at final height. After a mean period of 0.55±0.17yr off GH treatment 90 (66m/24 f) childhood-onset growth hormone deficiency (GHD) patients were reinvestigated for GHD ...
Takanashi Kuniko - - 2011
The clinical phenotype of congenital pituitary hormone deficiency is variable and can be associated with a number of structural abnormalities of the central nervous system. We report three Japanese patients with congenital pituitary hormone deficiency and ophthalmological anomalies. Two of the patients initially showed strabismus and unilateral optic nerve hypoplasia. ...
Bargren Anna E - - 2011
BACKGROUND: Primary hyperparathyroidism presents with a myriad of symptoms, which range in severity. The cause of these symptoms is not well understood. We sought to determine if the severity of preoperative biochemical abnormalities (calcium, parathyroid hormone, vitamin D levels) correlated with symptomatology in patients undergoing surgical treatment for primary hyperparathyroidism. ...
Akhoundi Fahimeh H - - 2011
OBJECTIVE: To investigate the protective effects of subclinical hypothyroidism (SCH) on ischemic stroke severity and its functional outcome. METHODS: Seventy-three consecutive patients admitted for first-ever cerebral ischemic stroke who met the inclusion criteria of this study were included. Serum thyroid-stimulating hormone (TSH) levels were measured for all patients. Stroke severity ...
Hoftijzer H C - - 2011
Context: Iodothyronine deiodinases D1, D2, and D3 play an important role in synthesis and degradation of T(3). The relationship between serum TSH and free T(4) (FT(4)) levels is determined by an individual set point of the hypothalamus-pituitary-thyroid axis. Objective: Several polymorphisms have been described in D1 and D2 of which ...
Iwata Shinichi - - 2011
BACKGROUND: Aortic valve stenosis (AS) is a frequent complication contributing to poor prognosis in chronic hemodialysis (CHD) patients. However, little is known regarding the risk factors affecting AS progression. The purpose of this study was to define risk factors affecting AS progression in CHD patients. METHODS: We retrospectively investigated 34 ...
Sobrinho L G - - 2011
It has been reported that women with prolactinoma were exposed, early in life, to an environment characterized by an absent or violent father. The present study was designed to evaluate whether paternal absence or violent paternal behavior were more prevalent in patients with pituitary adenomas (prolactinoma, acromegaly, non-secreting adenoma and ...
Bandak Mikkel - - 2011
INTRODUCTION: This study investigates the pituitary-Leydig cell axis in patients with stage I testicular germ cell cancer (TGCC) followed with surveillance only, in order to evaluate the risk of Leydig cell dysfunction one year after orchiectomy. PATIENTS AND METHODS: A retrospective evaluation of reproductive hormones in patients with unilateral stage ...
Mory Susana Barreto - - 2011
Studies have suggested that the thalamus is a key structure in the pathophysiology of juvenile myoclonic epilepsy. The objective of the present investigation was to examine the thalami of patients with juvenile myoclonic epilepsy using a combination of multiple structural neuroimaging modalities. The association between these techniques may reveal the ...
Nermoen Ingrid - - 2011
Background: Increased frequencies of adrenal tumours and testicular adrenal rest tumours (TART) have been reported in patients with 21-hydroxylase deficiency (21-OHD). Objective: Patients, methods and design: From a cross-sectional population-based study of 101 adult Norwegian patients with 21OHD, sixty-two participated in this study (23 men, 39 women; age range 18-75); ...
Ito Yasuhiro - - 2011
Cribriform-morular variant (CMV) is a comparably rare histological subtype of papillary thyroid carcinoma (PTC). This can be associated with familial adenomatous polyposis (FAP) due to APC gene mutations. In this study, we investigated the difference in the biological characteristics between FAP-associated and sporadic CMV. Between 1991 and 2010, 32 patients ...
Schneider Harald J - - 2011
Clinical studies demonstrated that traumatic brain injury (TBI) and aneurysmal subarachnoid hemorrhage (SAH) are frequent causes of long-term disturbances of hypothalamo-pituitary function. This study aimed to assess the prevalence and associated factors of post-traumatic hypopituitarism in a large national registry of patients with TBI and SAH. Data were collected from ...
Paragliola Rosa Maria - - 2011
Resistance to thyroid hormone (RTH) is a genetic disease characterized by a reduced responsiveness of the pituitary and peripheral target tissues to TH. We describe two patients with RTH in whom differentiated thyroid cancer was diagnosed. In both patients, RTH was unequivocally diagnosed and both underwent thyroidectomy for multinodular goiter. ...
Kokshoorn Nieke - - 2011
Objective: Hypopituitarism after traumatic brain injury (TBI) is considered to be a prevalent condition. However, prevalence rates differ considerably among reported studies, due to differences in definitions, endocrine assessments of hypopituitarism, and confounding factors, like timing of evaluation and the severity of the trauma. Aim: To evaluate the prevalence of ...
El Moussaif N - - 2011
INTRODUCTION: The mosaicism 45, X/46, XY is a gonosomal abnormality characterized by a broad phenotypic spectrum, ranging from women with or without Turner syndrome stigmata, to men apparently normal, passing by the ambiguous phenotypes with variable virilisation of external genitalia. From the histological point of view, several situations may arise. ...
Naranjo Antonio - - 2011
Acute renal failure is a relevant complication in obstructive jaundice (OJ). The extracellular water volume (ECW) depletion and myocardial dysfunction affects haemodynamic and renal disturbance in patients with OJ. A prospective open randomised study was conducted to evaluate the effect of peridrainage saline infusion associated with dopamine administration on hormonal ...
van Vledder Mark G - - 2011
To investigate the safety and efficacy of radiofrequency (RF) ablation for the treatment of hepatocellular adenoma (HCA). From 2000 to 2009, 170 patients with HCA were referred to a single tertiary hepatobiliary center. Medical records of 18 patients treated with RF ablation were retrospectively analyzed. All patients were female, and ...
Lee Ji In - - 2011
Graves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in high iodine intake area. In a cross-sectional setting, we collected serum from 67 patients with ...
Iglesias P P Department of Endocrinology, Hospital Ramón y Cajal, Madrid, Spain. - - 2011
An association between prolactin-secreting pituitary adenomas and anaemia in male patients has been recently reported. Our aim has been to evaluate the prevalence of anaemia in men with prolactinomas and to assess the relationships between haemoglobin concentrations and pituitary function at diagnosis in these patients. In a retrospective analysis, 26 ...
Kim Joon Ho - - 2011
High incidence of hypocalcemia after thyroidectomy is a major determinant in delay of discharge. Even though many studies have focused on the search for reliable early predictors of postoperative hypocalcemia, definitions of hypocalcemia are diverse; therefore, interpretation and application of previously reported findings may not be easy. We aimed to ...
Lupi Isabella - - 2011
Objective: some evidences suggest that late stage autoimmune hypophysitis (AH) may result in empty sella (ES). Aim of the study was to assess the prevalence of serum pituitary antibodies (PitAbs) and their correlation with pituitary function in patients with ES. Design: in this case-control study 85 patients with primary ES, ...
Padeh Shai - - 2011
OBJECTIVE: To assess linear growth in patients with persistent oligoarticular juvenile idiopathic arthritis (JIA) treated by intra-articular corticosteroid injections (IACSI). STUDY DESIGN: Data were obtained from a retrospective review of the charts of 95 patients with persistent oligoarticular JIA (69 females). The mean age at first visit was 4.9 ± ...
Lima Kari - - 2011
Objective: To characterize the endocrine and autoimmune disturbances with emphasis on parathyroid dysfunction in patients with 22q11.2 deletion syndrom. Design: In this nationwide survey; 59 patients (age 1 to 54 years) of 86 invited with a 22q11.2 DS were recruited through all the genetic institutes in Norway. Methods: Data were ...
Antonelli Alessandro - - 2011
Chemokine (CXC motif) ligand (CXCL)9 (CXCL9) has been shown to be involved in autoimmune thyroid disorders, however no data are present about CXCL9 circulating levels in chronic autoimmune thyroiditis (AT) vs controls. Serum CXCL9 (and for comparison CXCL10) has been measured in patients with AT vs normal control and nontoxic ...
Bellizzi Anna - - 2011
The recent introduction of monoclonal antibodies in Crohn's disease (CD) management has been associated with the development of serious complications, such as the progressive multifocal leukoencephalopathy (PML), caused by JC polyomavirus (JCV) reactivation. Therefore, the aims of our study have been the investigation of the possible JCV reactivation in pediatric ...
Park Hye Yoon - - 2011
Neurobiological abnormalities in various brain regions, including the orbitofrontal cortex, basal ganglia, and thalamus, have been found in patients with obsessive-compulsive disorder (OCD), and impairment in white matter connectivity in these regions has recently been suggested. To investigate structural connectivity in OCD, we used the midsagittal area and thickness to ...
Tektas Ozan-Yueksel - - 2011
Purpose: To analyze morphological changes in trabeculectomy specimens of patients suffering from uveitic secondary open angle glaucoma (UG). Material and Methods: Trabeculectomy specimens of six patients suffering from uveitis for 2 to 19 years and having been treated with steroids for 5 to 86 months were obtained during antiglaucomatous surgery ...
Cho Nancy L - - 2011
We aimed to validate the effectiveness of a protocol for primary hyperparathyroidism in which intraoperative parathyroid hormone measurement (IOPTH) was not routinely used during minimally invasive parathyroidectomy for patients with dual localization by technetium Tc 99m sestamibi (MIBI) and ultrasonography and hypothesized that our rate of surgical failure would be ...
Taddesse Abay - - 2011
To study the clinical presentation, thyroid function tests, ultrasound (US) features, cytology and surgical pathology results of patients undergoing fine needle aspiration (FNA) biopsy of thyroid nodules and to determine if a significant difference exists in the above variables between small (less than 1 cm) and large (1 cm or ...
Chen Yingming - - 2011
PURPOSE. To study the relationship between macular cone structure, fundus autofluorescence (AF), and visual function in patients with Stargardt disease (STGD). METHODS. High-resolution images of the macula were obtained with adaptive optics scanning laser ophthalmoscopy (AOSLO) and spectral domain optical coherence tomography in 12 patients with STGD and 27 age-matched ...
Szabó Nóra - - 2011
A retrospective population based survey of patients born with holoprosencephaly in South-Eastern Hungary between July 1, 1992 and June 30, 2006 was performed. All live birth cases with craniofacial and non-craniofacial abnormalities were included in the study. A total of 9 patients (5 boys and 4 girls) were found with ...
Bozzali Marco - - 2011
This study investigates the differential contribution of gray matter (GM) atrophy and deafferentation through white matter (WM) damage in the clinical progression of Alzheimer's disease (AD). Thirty-one patients with probable AD, 23 with amnestic mild cognitive impairment (a-MCI), and 14 healthy subjects underwent MRI scanning at 3T. Voxel-based morphometry was ...
Lai Chien-Han - - 2011
OBJECTIVE:: This study aimed to conduct a meta-analysis of published voxel-based morphometry studies in panic disorder (PD). METHODS:: Six data sets consisting of patients with PD and healthy controls were enrolled for this meta-analysis. A new improved voxel-based meta-analytic tool, signed differential mapping, was used to explore deficits of gray ...
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