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Quentien Marie-Hélène - - 2011
Context:Among 22 independent patients from the GENHYPOPIT network who had ACTH deficiency and no identified mutation of TPIT, three of them (13.6%) displayed common variable immunodeficiency (CVID), characterized by defective Ig production.Objective:Our objective was to describe an as yet unrecognized disease association.Design:We considered the hypothesis of ACTH deficiency being associated ...
Kovatcheva Roussanka D - - 2012
The recently developed non-invasive high-intensity focussed ultrasound (HIFU) technique for the destruction of parathyroid adenomas could also be of interest for the treatment of secondary hyperparathyroidism (SHP) in patients with chronic kidney disease (CKD). We conducted a pilot study using this method. Five chronic haemodialysis patients with severe SHP underwent ...
Hamnvik Ole-Petter Riksfjord - - 2011
Unlike cytotoxic agents that indiscriminately affect rapidly dividing cells, newer antineoplastic agents such as targeted therapies and immunotherapies are associated with thyroid dysfunction. These include tyrosine kinase inhibitors, bexarotene, radioiodine-based cancer therapies, denileukin diftitox, alemtuzumab, interferon-α, interleukin-2, ipilimumab, tremelimumab, thalidomide, and lenalidomide. Primary hypothyroidism is the most common side effect, ...
Rabelo-Júnior C N - - 2011
Objective: To perform a global gonadal and sexual functions assessment in primary antiphospholipid syndrome (PAPS) patients. Methods: A cross-sectional study was conducted in 12 male PAPS patients and 20 healthy controls. They were assessed by demographic data, clinical features, systematic urological examination, sexual function, testicular ultrasound, seminal parameters according to ...
Zheng Wei - - 2011
OBJECTIVE: To analyze the correlation therapeutic effects of first sufficiency I therapy in Graves' disease patients and improve its one-time curative ratio. METHODS: Seven hundred and sixty-six patients (age range 12-77 years, mean 40.46±13.12 years), including 237 men (range 12-77 years, 40.98±12.64 years) and 529 women (range 14-75 years, 40.22±13.34 ...
Kashine Susumu - - 2011
Sleep-disordered breathing (SDB), especially sleep apnea-hypopnea syndrome (SAS), is often observed in patients with active acromegaly. This complication is a risk factor for cardiovascular disease and associated with increased morbidity and mortality in acromegaly. However there is little information on SDB in Japanese patients with acromegaly. We investigated the prevalence ...
Bidet Maud - - 2011
Context:Resumption of ovarian activity and spontaneous pregnancies are described in patients with premature ovarian failure (POF), but there is a lack of data concerning the prevalence of and predictive factors for these phenomena.Objective:The aim of the study was to determine both the prevalence of and predictive factors for spontaneous resumption ...
Radetti Giorgio - - 2011
Objective:  The natural history of Hashimoto's thyroiditis (HT), and of isolated hyperthyrotropinaemia (IH) is not well defined. We therefore studied the natural course of patients with HT and IH and looked for possible prognostic factors. Design:  Retrospective cross-sectional study Patients:  323 patients with HT (88 m and 235 f,), and ...
Souto Selma B - - 2011
Amiodarone (AM)-induced thyrotoxicosis (AIT) is a condition with uncertainties from the diagnostic and therapeutic standpoints. A 54-year old male was referred to the hospital due to thyrotoxicosis. He had history of atrial fibrillation medicated with AM. No history of pre-existing thyroid disease was present, thyroid palpation revealed no goiter, and ...
Chen Yen-Kung - - 2011
Thymic hyperplasia is associated with hyperthyroidism. Increased thymus 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) uptake in hyperthyroidism patients has been reported. The aim of this study was to analyze the FDG positron emission tomography (PET) thymus uptake spectrum in patients with active hyperthyroidism with correlation with serum hormones. The prospective study included FDG PET ...
Olivero Juan Jose - - 2011
Vascular calcification in chronic kidney disease (CKD) is extremely common and contributes to significant morbidity and mortality among these patients. The pathogenesis is complex and involves multiple factors, including elevated calcium x phosphorus product as well as deficiencies in circulating or locally produced inhibitors of calcification, parathyroid hormone, hyperlipidemia and ...
Lo Sicco Kristen - - 2011
Thyroid dysfunction is classically associated with alopecia. Studies focusing on manual thyroid examinations, with ultrasonography of palpable abnormalities, in alopecia patients are lacking. To examine the clinical utility of manual and sonographic evaluation of the thyroid in alopecia patients. A retrospective chart review was performed among patients diagnosed with alopecia. ...
Nuzzo Vincenzo - - 2011
Urticaria is one of the most frequent dermatosis, being its prevalence in general population estimated about 20%. This prospective case-control study was aimed at determining the prevalence of thyroid autoimmune disorders in a cohort of patients with chronic urticaria (CU), all living within an area with mild-to-moderate iodine deficiency. Fifty ...
Stepien T - - 2011
Peripheral blood osteopontin (OPN) and endostatin (END) levels were studied in 35 patients with adrenal cortex tumors and 10 patients with pheochromocytoma before unilateral adrenalectomy, as well as in 10 healthy subjects (controls). Thirty days after surgery, OPN and END were evaluated again in 16 patients with adrenal cortex tumors ...
Chourdakis Michael - - 2011
BACKGROUND: Traumatic brain injury (TBI) results in a hypermetabolic and hypercatabolic status in which adequate nutrition support is essential to improve clinical outcome. The endocrine system of a patient with TBI is also affected and may play a critical role in either the metabolic or the immunologic response to the ...
Yamada Shozo - - 2011
Objective: The aim of this study was to determine the frequency and characteristics of severe growth hormone deficiency (sGHD) in patients after treatment of acromegaly by surgery alone.Design and Methods: one hundred eighty-six patients fulfilling the criteria for cure of acromegaly were examined by GH-releasing peptide-2 stimulation test or arginine ...
Hari Kumar K V S - - 2011
Objective - Vitiligo is a common depigmentation disorder due to autoimmune destruction of melanocytes. Autoimmune thyroid disease (AITD) is reported to have higher prevalence in this disease. Our objective was to identify the prevalence of AITD in vitiligo and to compare the clinical profile between antibody positive and negative groups.Methods ...
Koehler Edith - - 2012
Liver-related clinical consequences of non-alcoholic fatty liver disease (NAFLD) are seen only in the minority of patients with advanced fibrosis. The aim of our study was to generate insight into a potential endocrine basis of steatohepatitis with advanced fibrosis in NAFLD. Biopsy and blood samples were prospectively collected from patients ...
Tomova Capital A Cyrillic - - 2011
Anti-Müllerian hormone (AMH) is largely expressed throughout folliculogenesis and its levels may represent both the quantity and quality of ovarian follicle pool. We conducted this study to evaluate the levels of AMH in women with polycystic ovarian syndrome (PCOS) before and after metformin therapy. 22 consecutive patients with PCOS and ...
Vaphiades Michael S - - 2011
: Radiation therapy is often used in the treatment of pituitary tumor. Diplopia due to radiation damage to the ocular motor cranial nerves has been infrequently reported as a complication in this clinical setting. : Retrospective case series of 6 patients (3 men and 3 women) with pituitary adenoma, all ...
Alhefdhi Amal - - 2011
Intraoperative parathyroid hormone (IoPTH) testing is useful in the management of hyperparathyroidism. The successful removal of hypersecreting parathyroids is indicated by a decrease in PTH levels >50% within 15 min. A subset of patients with mild hyperparathyroidism will actually have starting PTH levels in the normal range. We sought to ...
Bahmani Kashkouli Mohsen - - 2011
We determined the frequency of clinical thyroid ophthalmopathy in Iranian patients. This cross-sectional study was performed at the Endocrinology Institute of Tehran University of Medical Sciences. All patients with documented thyroid disorders from September 2003 to July 2005 were recruited. Eye examinations included evaluation of soft tissue changes, measurement of ...
Basu Sandip - - 2011
A 35 years old primigravida hailing from a humble, rural background with no previous history related to thyroid carcinoma, presented with acute paraparesis at the last trimester of pregnancy and was diagnosed to harbor metastatic papillary thyroid carcinoma (PTC) following magnetic resonance imaging (MRI) of the spine with guided biopsy, ...
Tsai Andy - - 2011
Initial clinical presentation of knee venous malformation can mimic that of juvenile idiopathic arthritis, posing a diagnostic dilemma. In this communication, we discuss the diagnostic challenges encountered in children with venous malformation of the knee who were misdiagnosed as having juvenile idiopathic arthritis. We highlight the clinical and imaging differences ...
Giovanella Luca - - 2011
: To evaluate the relationship between postsurgical cervical Tc-99m-sestamibi scan uptake and the rate of successful remnant ablation after recombinant human-thyrotropin (rhTSH)-aided-I-131 ablation in patients with differentiated thyroid carcinoma (DTC). : In all, 154 DTC patients who underwent total thyroidectomy and rhTSH-aided remnant ablation with I-131 (3.7 GBq) were enrolled. ...
Comert M - - 2011
Intracranial and intraspinal involvement is a rare complication of Hodgkin's lymphoma. Intracranial involvement is observed in 0.2 to 0.5 percent of patients with Hodgkin's lymphoma. No specific risk factors associated with intracranial involvement have been found. We report intracranial involvement of Hodgkin's lymphoma in a patient who had previously undergone ...
Yin Hongyan - - 2011
We retrospectively analyzed iodine-131 metaiodobenzylguanidine (I-131 MIBG) scintigraphy in 320 patients (male, 108 cases; female, 211 cases; average age, 45 ± 15 years). All patients received thyroid block before examination between 2007 and 2010 in our department. Various degrees of radioactivity were found in the thyroid glands or thyroid region ...
de Mestier L - - 2011
Pachydermoperiostosis (PDP) is the primary form of hypertrophic osteoarthropathy. It is a very rare disease consisting of pachydermia, digital clubbing and radiologic periostosis. Various digestive symptoms in PDP are seen in 11-49% of patients and juvenile polyps may be found at gastric endoscopy. We report here the history of a ...
Tárraga López Pedro J - - 2011
to estimate the prevalence of osteoporosis in patients being treated with thyroid hormone. cross-sectional retrospective study of primary care patients. EXPERIMENTAL GROUP: patients diagnosed with subclinical hypothyroidism receiving thyroid hormone replacement therapy. patients not receiving replacement therapy. Once the sample was selected its members were summoned to complete a clinical ...
Dhanwal Dinesh K - - 2011
Acute and chronic central nervous system (CNS) infections are not uncommon in tropical countries and are associated with high morbidity and mortality if specific targeted therapy is not instituted in time. Effects of tubercular meningitis, a form of chronic meningitis on hypothalamic pituitary axis, are well known both at the ...
Kachuei Maryam - - 2011
INTRODUCTION: Hypothyroidism is associated with pregnancy complications both for the mother and progeny and it should be considered in reproductive age. Thyroid autoimmunity is stated to be the main cause of hypothyroidism in iodine sufficient areas. Polycystic ovary syndrome (PCOS) is known as the most common endocrine disorder affecting women ...
Moon Seong-Su - - 2011
BACKGROUND: An elevated thyroid stimulating hormone (TSH) level is a risk factor for differentiated thyroid cancer. The present study investigated whether TSH is a risk factor for thyroid microcarcinoma (TMC) in euthyroid subjects with a micronodule. METHODS: In this cross-sectional study, 483 euthyroid subjects (77 males patients, 406 females patients) ...
Isik Serhat - - 2011
Objective:  Impaired gallbladder (GB) emptying is a well-documented contributor to gallstone formation. The aim of this study was to evaluate GB motility in patients with polycystic ovary syndrome (PCOS). Methods:  The study population consisted of 36 PCOS patients and 20 healthy controls. GB volume was calculated using the ellipsoid formula ...
Bogazzi Fausto - - 2011
Context: Type 2 amiodarone-induced thyrotoxicosis (AIT) is a destructive thyroiditis usually responsive to glucocorticoids. Whether continuation of amiodarone affects treatment outcome is unsettled. Objective: The objective of the study was to compare the outcome of glucocorticoid treatment in type 2 AIT patients who continued or withdrew amiodarone. Design: This was ...
Gómez-Ramírez Joaquín - - 2011
INTRODUCTION: Scintigraphy with technetium-sestamibi (MIBI) is the test of choice for localising adenomas in patients with primary hyperparathyroidism (PHPT). In some studies it has emerged that the increase in sensitivity of this test could be associated with a decrease in the uptake of the radiotracer by the thyroid gland. The ...
Diamanti Antonella - - 2011
Background Thyroid autoimmunity (TA) is often associated with coeliac disease (CD). Objective To evaluate, in children and adolescents with CD on a gluten-free diet (GFD): (1) the prevalence of TA; (2) the impact of TA on growth and the need for L-thyroxine (L-T4) treatment, during a longitudinal survey. Method Between ...
Turchi Federica - - 2011
BackgroundA positive correlation between thyroid-stimulating hormone (TSH) and blood pressure (BP) has been identified in normotensives and in patients with essential hypertension (EH). This study was designed to evaluate, in primary aldosteronism (PA) and in EH, potential association of BP, TSH, and ultrasonographic changes of the thyroid.MethodsWe studied 188 patients: ...
Schomäcker Klaus - - 2011
PURPOSE: A considerable amount of radioiodine is exhaled after radioiodine therapy leading to unwanted radiation exposure through inhalation. This study focused on the concentration of radioactivity exhaled and its chemical nature. METHODS: Air exhaled by 47 patients receiving (131)I-iodine for different thyroid diseases (toxic goitre n = 26, Graves' disease n = 13, thyroid ...
Huttner Hagen B - - 2011
BACKGROUND: Neuroendocrine changes have been reported after ischemic stroke, subarachnoid hemorrhage, and brain trauma. As there are no corresponding data in patients with intracerebral hemorrhage (ICH) we analyzed various neuroendocrine parameters to investigate possible alterations in hormone profiles of patients with ICH. METHODS: Twenty patients with ICH were prospectively enrolled ...
Akizawa Tadao - - 2011
Control of serum concentrations of calcium (Ca), phosphorus (P), and parathyroid hormone (PTH) is essential for management of secondary hyperparathyroidism (SHPT). This is a planned interim analysis of a longitudinal cohort study. The settings are dialysis facilities in Japan. Eligible patients comprise all those who were receiving hemodialysis at one ...
Hansen Ditte - - 2011
Alfacalcidol and paricalcitol are vitamin D analogs used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease, but have known dose-dependent side effects that cause hypercalcemia and hyperphosphatemia. In this investigator-initiated multicenter randomized clinical trial, we originally intended two crossover study periods with a washout interval in ...
Maruyama E - - 2011
Maruyama E, Minami N, Niino M, Fujiki N, Doi S, Watanabe M, Shima K, Kikuchi S, Sasaki H. Impact of screening with thyroid ultrasonography in patients with myasthenia gravis. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01580.x. © 2011 John Wiley & Sons A/S. Objectives -  This study was conducted to screen thyroid abnormality ...
Yoon Yeo-Hoon - - 2011
The goal of this study is to determine the clinicopathologic differences in patients with papillary thyroid carcinoma (PTC) with or without chronic lymphocytic thyroiditis (CLT). We reviewed the medical records of 195 consecutive PTC patients who underwent total thyroidectomy and bilateral central lymph node dissection from April 2008 to March ...
Bahammam Salman A - - 2011
OBJECTIVES: Studies have suggested that ethnicity and environment may influence thyroid disease. We aim in this study to determine the prevalence of thyroid disease among Saudi (Arab) patients with laboratory-diagnosed obstructive sleep apnea (OSA) and the characteristics and predictors of thyroid disease associated with OSA. METHODS: Serum thyroid-stimulating hormone (TSH) ...
Zweifel Christian - - 2011
Background: Endocrine alterations of the hypothalamic-pituitary-axis are one of the first measurable physiological changes in cerebral insults. During acute stress, human growth hormone (GH) is stimulated and has shown to have a prognostic value in various diseases. Within this pilot study, we evaluated the prognostic value of GH in patients ...
Andereggen Lukas - - 2011
INTRODUCTION: Conventional MRI may still be an inaccurate method for the non-invasive detection of a microadenoma in adrenocorticotropin (ACTH)-dependent Cushing's syndrome (CS). Bilateral inferior petrosal sinus sampling (BIPSS) with ovine corticotropin-releasing hormone (oCRH) stimulation is an invasive, but accurate, intervention in the diagnostic armamentarium surrounding CS. Until now, there is ...
Monroy-Santoyo Susana - - 2011
BACKGROUND: Congenital hypothyroidism (CH) is the most common endocrine system disorder in newborns. Ectopic thyroid and agenesis are the most frequent thyroid structural malformations. Several reports have shown that CH is associated with birth defects (BD) ranging from congenital heart disease to ocular and gastrointestinal anomalies. AIMS: We investigated how ...
Andrade Luis Jesuino de Oliveira - - 2011
To investigate the frequency of thyroid disorders (TD) in patients with chronic hepatitis C before and during interferon-alpha (IFN-α) and ribavirin (RIB) treatment. Prospective study. We prospectively studied 65 anti-HCV and viral RNA positive patients. Free thyroxine, thyroid-stimulating hormone, and thyroid peroxidase antibodies (TPO-Ab) were systematically tested at entry (m0), ...
Miyara Tetsuhiro - - 2011
Our aim was to investigate the incidence and characteristics of bronchial diverticula using multidetector-row computed tomography (MDCT) and to evaluate their association with smoking status. Two radiologists retrospectively reviewed MDCT scans obtained between December 2007 and February 2008 with a 4-row or a 64-row MDCT scanner for 1122 consecutive patients. ...
Anari Hassan - - 2011
Ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. This study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. From March 2008 to March 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 ...
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