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Wildemberg Luiz Eduardo Armondi - - 2012
Objectives: to describe two patients who developed pituitary apoplexy during the course of dengue hemorrhagic fever (DHF).Methods: case report.Results: the first case was a 40-year-old male who developed clinical signs and symptoms of dengue, which was confirmed by serologic exam. He presented with thrombocytopenia and developed severe headache and vomiting. ...
Hána V - - 2012
Relatively frequent pituitary hormone deficiencies are observed after traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH) and according to the published studies the neuroendocrine consequenses of traumatic brain injury are underdiagnosed. In a cohort of 59 patients (49 males, mean age 68.3 years, 36-88 years) after evacuation of subdural hematoma ...
Imbriano Louis J - - 2012
Background: Reset osmostat (RO) occurs in 36% of patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH) and is not often considered when evaluating hyponatremic patients. Patients with RO are not usually treated, but recent awareness that symptoms are associated with mild hyponatremia creates a therapeutic dilemma. We encountered patients ...
Lin Yen-Chung - - 2012
The population of uremia patients receiving long-term peritoneal dialysis (PD) is growing, and abnormal thyroid function occurs increasingly in patients with chronic kidney disease in comparison with the normal population. We aimed to elucidate the clinical impact of abnormal thyroid function in long-term PD patients. This was a retrospective, case-controlled, ...
Law Ryan - - 2012
Current endoscopic pancreatic function test (ePFT) methods use either secretin or cholecystokinin (CCK) to measure pancreatic function. To evaluate a novel ePFT protocol that includes both secretin and CCK stimulation and to assess which fluid parameters best discriminate patients with chronic pancreatitis (CP). Prospective, cross-sectional diagnostic study. Single, tertiary-care institution. ...
Gimm Oliver - - 2012
Selective venous sampling (SVS) helps to interpret imaging results in patients with persistent primary hyperparathyroidism (pHPT). However, one of the drawbacks of conventional SVS may be low "spatial resolution", depending on the sample size. We modified SVS in the following way: first, patients underwent conventional SVS with up to 11 ...
Petrowski Katja - - 2012
BACKGROUND: Panic disorder (PD) has been associated with the altered circadian rhythm of the hypothalamic-pituitary-adrenocortical (HPA) axis. The findings regarding the stress-specific functioning of the HPA-system are inconsistent. It is also unclear whether the HPA-system response after the Corticotropin-Releasing-Hormone (CRH) challenge becomes altered. METHODS: For this study, the dexamethasone-corticotropin-releasing-hormone (DEX-CRH) ...
Doin Fabio Casanova - - 2012
Objective: The diagnosis of subclinical central hypothyroidism in hypothalamic-pituitary patients cannot be established by serum markers of thyroid hormone action. Myocardial function by echocardiography has been shown to reflect thyroid hormone action in primary thyroid dysfunction. We evaluated the performance of echocardiography in diagnosing subclinical central hypothyroidism.Design: Cross-sectional and Before ...
Laird Amanda M - - 2012
BACKGROUND: Prophylactic central lymph node dissection (CLND) accompanying total thyroidectomy for papillary thyroid cancer (PTC) remains controversial. Our hypothesis is that CLND may help select patients who benefit from postoperative radioactive iodine (RAI). METHODS: A total of 119 patients who were clinically node-negative underwent total thyroidectomy/bilateral CLND for papillary thyroid ...
Ragnarsson Oskar - - 2012
Objective: Cushing's disease (CD) and non-functioning pituitary adenoma (NFPA) are rare in paediatric patients. The aim of this study was to describe long-term consequences in adults with GH deficiency (GHD) treated for CD or NFPA during childhood.Design, patients and methods: This was a retrospective analysis of data from KIMS (Pfizer ...
van Wamelen Daniel J - - 2012
Neuroendocrine, metabolic and autonomic nervous system dysfunction are prevalent among patients with Huntington's disease (HD) and may underlie symptoms such as depression, weight loss and autonomic failure. Using post-mortem paraffin embedded tissue, we assessed the integrity of the major neuropeptide populations in the paraventricular nucleus (PVN) - the hypothalamic neuroendocrine ...
Park Jin Hee - - 2012
The spontaneous and serial rupture of the bilateral Achilles tendons without history of significant trauma is an uncommon complication in long-term hemodialysis (HD) patients. The majority of these patients have additional predisposing factors, such as previous use of fluoroquinolone antibiotics or corticosteroids. In general, this condition is associated with a ...
Clerc Jérôme - - 2012
Context:In low-risk differentiated thyroid cancer (DTC), postoperative (131)I remnant ablation should employ a minimum effective activity; reports increasingly suggest efficacy of low activities, e.g. 1110 MBq/30 mCi.Objectives, Design, Patients, and Interventions:We retrospectively studied the ablation capability and diagnostic utility of the Minidose protocol, two 740-MBq/20 mCi outpatient administrations, 6-18 months ...
Martinerie Laetitia - - 2012
ContextGender assignment followed by surgery and hormonal therapy is a difficult decision in the management of 45,X/46,XY patients with abnormal external genitalia at birth considering the paucity of studies evaluating pubertal development and fertility outcome, most notably for patients raised as boys.ObjectiveThe purpose of the present study was to describe ...
Tanriverdi F - - 2012
Previous case reports and retrospective studies suggest that pituitary dysfunction may occur after acute bacterial or viral meningitis. In this prospective study we assessed the pituitary functions, lipid profile and anthropometric measures in adults with acute bacterial or viral meningitis. Moreover, in order to investigate whether autoimmune mechanisms could play ...
Rosario Pedro Weslley - - 2012
Background: In the presence of anti-thyroglobulin antibodies (TgAb), serum thyroglobulin (Tg) might be underestimated. Therefore, the American Thyroid Association does not recommend serum Tg after thyroid hormone withdrawal or recombinant human thyrotropin administration (stimulated Tg) and diagnostic whole-body scanning (DxWBS) in TgAb-positive patients who have serum Tg values while on ...
Magen Eli - - 2012
Autoimmune thyroiditis (AT) is more prevalent in patients with chronic idiopathic urticaria CIU) than in the general population. Previous small studies without any controlled comparison reported that CIU remits in patients with CIU and AT treated with l-thyroxine. To determine whether l-thyroxine treatment can improve the clinical course of CIU ...
Duran Cevdet - - 2012
Aim. Colonic polyps and thyroid nodules are common diseases and their frequency increases with age. In the literature, there is no study investigating the coexistence of colonic polyps and thyroid nodules. Therefore, this study was designed to investigate thyroid nodule prevalence in patients with colonic polyps. Material and Methods. Sixty-six ...
Horak Petr - - 2012
Aim. To determine if hormonal treatment induces apoptosis in uterine fibroids. Methods. Immunohistochemical examination of fibroid tissue, using avidin-biotin complex and cleaved caspase-3 antibody for detecting apoptosis, was performed in premenopausal women who underwent 12-week treatment with oral SPRM (6 patients with 5 mg and 5 patients with 10 mg of ulipristal ...
Pierrakos Charalampos - - 2012
Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been reported in this population. This is a ...
Catli Gonul - - 2012
The aim of this study is to evaluate the clinical, anthropometric, hormonal, and radiological characteristics of children with central diabetes insipidus (DI). Case records of 34 children (22 boys and 12 girls) with documented central DI referred to the Pediatric Endocrinology and Adolescent Clinic of Dokuz Eylul University Faculty of ...
Abonowara Abdulgani - - 2012
Background: Suppression of thyroid stimulating hormone (TSH) below the normal range with administration of L-thyroxine has been shown to improve survival in patients treated for thyroid cancer (TC). Although most TC patients require long-term TSH suppression therapy, the effect of this treatment on cardiac rhythm remains unknown. A cross-sectional study ...
Mandel Louis - - 2012
Treatment for otosclerosis involves patients' undergoing stapedectomy. Inadvertent damage to the chorda tympani nerve's (CTN's) secretory fibers during stapedectomy can result in inadequate secretory stimulation of the submandibular salivary glands (SMSGs) and sublingual salivary glands (SLSGs). Because most saliva originates from these glands, hyposalivation and subjective xerostomia manifest during resting ...
Moran Carlos - - 2012
Obesity or overweight affect most of patients with polycystic ovary syndrome (PCOS). Phenotypes are the clinical characteristics produced by the interaction of heredity and environment in a disease or syndrome. Phenotypes of PCOS have been described on the presence of clinical hyperandrogenism, oligoovulation and polycystic ovaries. The insulin resistance is ...
Khandelwal Deepak - - 2012
Hypothyroidism denotes deficient production of thyroid hormone by the thyroid gland and can be primary (abnormality in thyroid gland itself) or secondary/central (as a result of hypothalamic or pituitary disease). The term 'subclinical hypothyroidism' is used to define that grade of primary hypothyroidism in which there is an elevated thyroid-stimulating ...
Thewjitcharoen Yotsapon - - 2012
Severe hypercalcemia has rarely been reported in patients with hyperthyroidism. Although the pathogenesis is not clear; it is believed to be due to activation of osteoclasts resulting in excessive bone resorption. To recognize the unusual cause of hypercalcemia from painless thyroiditis, which could manifest with transient hyperthyroidism in the early ...
Koivula Marja-Kaisa - - 2012
IDS-iSYS intact parathyroid hormone (iPTH) assay was evaluated. Two automated second generation assays for measuring iPTH were also compared to each other. The compared assays detected PTH fragments 1-84 and 5-84. The iPTH was analyzed from controls (n = 88) and samples of patients with chronic kidney disease (CKD) (n ...
Nowroozi Mohammad Reza - - 2012
Sperm recovery by testicular fine-needle aspiration (TESA) has resulted in variable sperm retrieval rate (SRR) and is generally considered inferior to open biopsy (testicular sperm extraction [TESE]). To develop a predictive model for SRR by TESA and to identify factors associated with comparable SRR between TESA and TESE. Single-center controlled ...
McCorquodale Tom - - 2012
Ophthalmopathy is the most common extrathyroidal manifestation of Graves' disease. However, in approximately 5% of cases this autoimmune eye disorder occurs in the apparent absence of Graves' hyperthyroidism: the so-called euthyroid Graves' disease (EGD). Seven patients with EGD were followed for evidence of thyroid and orbital autoimmunity, for up to ...
Bensenor Isabela M - - 2012
Thyroid disorders are highly prevalent, occurring most frequently in aging women. Thyroid-associated symptoms are very similar to symptoms of the aging process; thus, improved methods for diagnosing overt and subclinical hypothyroidism in elderly people are crucial. Thyrotropin measurement is considered to be the main test for detecting hypothyroidism. Combined evaluations ...
Takeuchi Takako T Department of Pediatrics, Sapporo Medical University School of Medicine, Japan. - - 2012
Iodine concentrations of enteral nutrition (EN) formulae available in Japan are very low and long-term total EN (TEN) might result in hypothyroidism due to iodine deficiency (HID). Our aim of this study was to determine the degree of iodine deficiency (ID) and need for iodine supplementation (IS) in patients with ...
Cárdenas Graciela - - 2011
Neurocysticercosis (NC) is a parasitic disease caused by the infiltration of the larval stage of Taenia solium in the central nervous system. Clinical presentations are heterogeneous and particularly depend, on the age and gender of the host. We designed a clinical study to evaluate the hormonal changes associated with neurocysticercosis ...
Regalbuto Concetto - - 2012
Percutaneous ethanol injection (PEI) is used to treat cystic or mixed benign thyroid nodules. This treatment can result in rare complications, and three cases of Graves' disease (GD) without Graves' ophthalmopathy (GO) have been reported after PEI treatment of toxic thyroid adenomas. Here we present a 55-year-old male patient who ...
Cappa M - - 2011
Background: No data are available about the risk of thyroid disturbance after exposure of low dose radiation due to the use of cardiac catheterization in the first years of life. Aim: To determine the risk of functional and morphological thyroid abnormalities in a homogeneous cohort of patients who underwent diagnostic ...
Brzana Jessica A - - 2011
New criteria that define acromegaly remission are more stringent: normal (age/sex-adjusted) insulin-like growth factor type 1 (IGF-1), growth hormone (GH) random (GHr) <1 μg/L, and a GH nadir (GHn) during oral glucose tolerance test (OGTT) of <0.4 μg/L. Discordance between GH and IGF-1 values is often attributed to somatostatin receptor ligands (SRLs) ...
Liu Z-H - - 2011
Background and purpose:  The clinical features of pituitary adenomas were retrospectively analyzed, focusing on the factors that contribute to the development of pituitary hemorrhage. Although many causes of pituitary adenoma hemorrhage have been identified, it is difficult to distinguish which conditions are truly causative. We determined the independent variables that ...
Carvalho Maria Raquel - - 2012
Previous studies demonstrated that preparation with recombinant human thyroid-stimulating hormone (rhTSH) for thyroid remnant ablation results in lower extrathyroidal radiation compared to hypothyroidism. The results of 50 radioiodine therapies (RITs) under rhTSH, regarding iodine half-life, were evaluated and compared with 50 RITs performed on patients with hypothyroidism following thyroxine withdrawal. ...
Uematsu Mitsugu - - 2011
Mutations in NKX2-1 cause neurological, pulmonary, and thyroid hormone impairment. Recently, the disease was named brain-lung-thyroid syndrome. Here, we report three patients with brain-lung-thyroid syndrome. All patients were unable to walk until 24months of age, and still have a staggering gait, without mental retardation. They have also had choreoathetosis since ...
Sakly Wahiba - - 2011
Aim. To evaluate, retrospectively, the frequency of antithyroid antibodies (ATA) in patients with type 1 diabetes (T1D). Materials and methods. Antithyroperoxidase antibodies (TPO-Ab), antithyroglobulin antibodies (TG-Ab), and antithyroid-stimulating hormone receptor antibodies (TSHR-Ab) were determined by enzyme-linked immunosorbent assay. Sera of 312 patients (166 children and 146 adults) with T1D were ...
Guo M - - 2011
OBJECTIVE: Aim of the study was to evaluate whether growth hormone (GH), glutamine (Gln), and enteral nutrition (EN) have a positive effect on intestinal adaptation in pediatric patients with short bowel syndrome (SBS). METHOD: 7 pediatric patients with SBS (small bowel remnant length: 60.57±15.18 cm; mean±SEM) were treated with GH (0.05 mg/kg/day), ...
Banks Caroline A - - 2011
OBJECTIVES/HYPOTHESIS: Compressive symptoms are common in thyroid disease, but few studies have focused on the presence, associated factors, and etiology of compressive symptoms. STUDY DESIGN: Retrospective review. METHODS: Patients who underwent thyroidectomy from 2005 through 2009 were reviewed. The data included demographics, indication for surgery, compressive symptoms, complications, diagnosis, volume ...
Ruchala Marek - - 2011
Objective: Reports on sonoelastography, which provide an objective estimation of tissue elasticity, are scarce in terms of thyroiditis. The aim of the study was to prospectively assess the applicability of sonoelastography in different types of thyroiditis.Design: The study assessed and compared the thyroid tissue stiffness in patients with acute (AT), ...
Wallace Lucy B - - 2011
While normocalcemic hyperparathyroidism is well recognized in primary hyperparathyroidism (PHP), less is known about patients with high calcium but normal intact parathyroid hormone (iPTH). We aimed to describe this entity and designated it normohormonal primary hyperparathyroidism (NHPHP). From a prospectively maintained database of patients undergoing bilateral parathyroid exploration for PHP, ...
Poola Rama - - 2011
The treatment of subclinical hyperthyroidism is controversial because the natural history is uncertain. We undertook a retrospective study to examine the natural history of endogenous subclinical hyperthyroidism. Between 2002 and 2006, we identified 116 patients with thyroid-stimulating hormone (TSH) concentrations <0.4 microIU/mL but normal free thyroxin and triiodothyronine or free ...
Cho Jin Seong - - 2011
We investigated the incidence and risk factors of hypothyroidism after thyroid lobectomy, and evaluated the possibility to predict hypothyroidism preoperatively with serologic markers, such as thyrotropin (TSH), thyroglobulin (TG), anti-thyroglobulin (ATA), and anti-microsomal antibody (AMA). We enrolled 123 consecutive patients who underwent thyroid lobectomy due to benign conditions between May ...
Gatta Blandine - - 2011
AbstractObjectiveLimited data regarding adrenal involvement in MEN1 is available. We describe the characteristics of MEN1-associated adrenal lesions in a large cohort to provide a rationale for their management.MethodsAnalysis of records from 715 MEN1 patients from a multicenter database between 1956 and 2008. Adrenal lesions were compared to those from a ...
Rotondo Fabio - - 2011
Ghrelin, an orexigenic hormone, is known to occur in the normal anterior pituitary where its physiologic role is uncertain but may include promotion of appetite. We sought to investigate anticipated differences in adenohypophysial and neurohypophysial ghrelin immunoexpression between normal subjects and patients with anorexia nervosa who had succumbed to complications ...
Jonklaas Jacqueline - - 2011
Thyroidectomized patients frequently report weight gain resistant to weight loss efforts, identifying their thyroidectomy as the event precipitating subsequent weight gain. We wished to determine whether recently thyroidectomized euthyroid patients gained more weight over 1 year than matched euthyroid patients with preexisting hypothyroidism. We performed a retrospective chart review of ...
Cappelli C - - 2011
Background: The European Thyroid Association (ETA) and the American Thyroid Association (ATA) guidelines identify subgroups of patients affected by thyroid carcinoma in whom, due to a low risk of recurrence, radioiodine ablation is not indicated. These patients, are referred to as "very low risk" according to the ETA consensus and ...
Alimoglu Yalcin - - 2011
We present a 69-year-old male patient with the macroglossia, dysphagia and generalized edema. He was seen previously by other physicians and diagnosed as hypothyroidism. With thyroid stimulating hormone in normal range, tongue biopsy revealed primary systemic amyloidosis. Amyloidosis is the most common cause of macroglossia. Primary systemic amyloidosis should be ...
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