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Lopes Agnaldo José AJ Rehabilitation Sciences Master's Program, Augusto Motta University Centre, Brazil. Electronic address: - - 2014
Acromegaly is a chronic debilitating disease that presents with multiple systemic manifestations, including changes in body composition, joint abnormalities, muscular impairment and visual disturbances. This study aimed to assess posture and body balance in acromegalic patients and to establish the correlation between these measures. Twenty-eight acromegalic patients and a similar ...
Cizman Borut B Renal Therapeutic Area, Baxter Healthcare Corporation, Deerfield, United - - 2014
Background, objectives and methods: Increased intraperitoneal volume (IIPV) can occur during automated peritoneal dialysis (APD). The contribution of factors such as cycler programming and patient/user actions to IIPV has not been previously explored. The relationship between IIPV and cycler programming, patient/user actions, and ultrafiltration over a two-year period was investigated ...
Hammoudi Nadjib N Department of Cardiology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Faculté de Médecine Pierre et Marie Curie, university Paris 6, Paris, France; Institute of Cardiometabolism and Nutrition (ICAN), Paris, France. Electronic address: - - 2014
Management of increased referrals for transthoracic echocardiography (TTE) examinations is a challenge. Patients with normal TTE examinations take less time to explore than those with heart abnormalities. A reliable method for assessing pretest probability of a normal TTE may optimize management of requests. To establish and validate, based on requests ...
Yamada Kentaro K Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, - - 2014
The effect of diffuse idiopathic skeletal hyperostosis (DISH) on spinopelvic alignment in patients with lumbar spinal stenosis (LSS) remains unclear. The aim of this study was to investigate the association between DISH and sagittal spinopelvic alignment in patients undergoing surgery for LSS. A total of 132 patients aged >40 years who ...
Eikelboom John W JW McMaster University, Hamilton Health Sciences, Hamilton, - - 2014
Christensen and Larsen suggest that patients randomized to receive warfarin in the recently published RE-ALIGN randomized trial (1) were sub-optimally managed, citing lack of use of aspirin and poor control of anticoagulation. The RE-ALIGN trial was conducted in a real world setting and left responsibility for use of aspirin and ...
Ahammad Nabeel N Department of Electrical Engineering, National Institute of Technology, Calicut, Kerala 673601, - - 2014
This study proposes a method of automatic detection of epileptic seizure event and onset using wavelet based features and certain statistical features without wavelet decomposition. Normal and epileptic EEG signals were classified using linear classifier. For seizure event detection, Bonn University EEG database has been used. Three types of EEG ...
Geurtsen Gert J - - 2013
Dementia in Parkinson's disease (PD) is a serious health issue and a major concern for many patients. In most cases mild cognitive impairment (MCI) is considered a transitional stage between normal cognitive functioning and dementia which is of potential importance in the early identification of patients at risk for dementia. ...
Santos Thiago M - - 2013
Lung ultrasound (US) is an excellent tool to assess lung edema in a myriad of different clinical situations. We hypothesized that lung US might also be a good prognostic and management instrument in septic patients, regardless of disease severity. This was a prospective observational cohort study at an urban academic ...
Yayan Josef J Department of Internal Medicine, University Hospital of Saarland, Homburg, Saarland, - - 2013
Alteplase is used to treat acute ischemic stroke. However, it has several documented adverse effects, including the development of orolingual angioedema (OA). Although, OA is a rare side-effect, it is thought to be life-threatening and is difficult to treat. Until date, little is known about this condition and a better ...
Johannessen Rune - - 2013
Abstract Objective. Dilated intercellular space (DIS) in esophageal biopsies is regarded as a possible early sign of mucosal injury in gastroesophageal reflux disease (GERD). This study presents a standardized approach of intercellular space measurement. Material and methods. Distal and proximal esophageal biopsies were taken from 19 patients with suspected GERD, ...
Jepsen Peter - - 2013
& Aims: At least 40% of patients with cirrhosis have comorbidities, which increase mortality. We developed a cirrhosis-specific comorbidity scoring system (CirCom) to help determine how these comorbidities affect mortality, and compared it with the generic Charlson Comorbidity Index. We used data from nationwide healthcare registries to identify Danish citizens ...
Smith Justin S - - 2013
Study Design: Post-hoc analysis of prospectively collected data.Objective: Development of methods to determine in vivo spinal cord dimensions and application to correlate preoperative alignment, myelopathy, and health-related quality of life (HRQOL) scores in patients with cervical spondylotic myelopathy (CSM).Summary of Background Data: CSM is the leading cause of spinal cord ...
Pan Jinfeng - - 2013
A molecular and pathological classification system for hepatocellular adenomas (HCAs) was recently introduced in Europe, resulting in four major identified subgroups. Asian countries have a considerably lower incidence of HCA as well as a different etiology. We aimed to characterize HCAs in a Chinese population based on this new classification ...
Jonasson Christian - - 2013
Abstract Objective. To assess the drug utilization patterns for proton pump inhibitors (PPIs) prescriptions dispensed in periods with and without restrictions on reimbursement in a public healthcare system. Material and methods. Data on all PPI prescriptions dispensed for gastroesophageal reflux disease (GERD) was retrieved from the Norwegian Prescription Database (NorPD) ...
Victor Jan M K - - 2013
BACKGROUND: In a previous study, we described the distribution of coronal alignment in a normal asymptomatic population and recognized the occurrence of constitutional varus in one of four individuals. It is important to further investigate the influence of this condition on the joint line orientation and how the latter is ...
Rostaminia Ghazaleh - - 2013
: To estimate whether levator ani deficiency severity is a predictor of clinically significant pelvic organ prolapse (POP) and to determine whether there is a levator ani deficiency threshold above which POP occurs. : Two-hundred twenty three-dimensional ultrasound scans performed on urogynecologic clinic patients were reviewed, and each levator ani ...
Fleet Jamie L - - 2013
BACKGROUND: Large, population-based administrative healthcare databases can be used to identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results are unavailable. We examined the validity of algorithms that used combined hospital encounter and physician claims database codes for the detection of CKD in Ontario, Canada. METHODS: We ...
Sá Tiago - - 2013
INTRODUCTION AND OBJECTIVES: Cardioembolism is one of the most common causes of ischemic stroke, with an estimated prevalence of 20-30%, and correct diagnosis is essential given the therapeutic implications. Although stroke risk scores (CHADS2 and more recently CHA2DS2-VASc) have been validated in heterogeneous populations of patients with atrial fibrillation, their ...
Shi Hai Cun - - 2013
Voxel-based morphometry (VBM) studies have provided cumulative evidence of gray matter (GM) atrophy in patients with progressive supranuclear palsy (PSP) relative to healthy controls (HC). However, not all findings have been entirely concordant. Herein, we performed a quantitative meta-analysis study in order to consistently quantify GM anomalies in PSP. We ...
Bervet Kristell - - 2013
PURPOSE: To define a new index of gait pathology in adults based on electromyographic data: the Ker-EGI for Kerpape-Rennes EMG-based Gait Index. The principle is similar to the one of Gait Deviation Index but using EMG profiles instead of joint angles. It first needs to build a database of healthy ...
Attallah Abdelfattah M - - 2013
BACKGROUND: We aimed to derive a simple noninvasive test for liver-fibrosis staging and then estimate its performance against four simple noninvasive tests in chronic hepatitis C (CHC) patients. METHODS: CHC patients were divided into two cohorts: an estimation set (n = 324) and a validation set (n = 524). Liver fibrosis was staged according ...
Harroud Adil A Faculty of Medicine, University of Montréal, Montréal, - - 2013
Global sagittal alignment is considered as an important aspect in the management of spinal disorders, but the evidence establishing its clinical impact in lumbosacral spondylolisthesis is still poor. This study evaluated the impact of global sagittal alignment on the health-related quality of life (HRQOL) of patients with spondylolisthesis. A retrospective ...
Gullung Jessica L - - 2012
Deglutition is a highly integrated process of neural signaling and coordinated muscular contraction that begins with bolus preparation in the oral cavity and ends with closure of the lower esophageal sphincter after bolus passage. The goal of this study was to examine the relationship between measures of oropharyngeal and esophageal ...
Parker Emily D ED HealthPartners Institute for Education and Research, Minneapolis, Minnesota 55440-1524, USA. - - 2012
Randomized controlled trials have demonstrated the efficacy of selected β-blockers for preventing cardiovascular (CV) events in patients following myocardial infarction (MI) or with heart failure (HF). However, the effectiveness of β-blockers for preventing CV events in patients with hypertension has been questioned recently, but it is unclear whether this is ...
Mann Nirmal S - - 2012
Key Words: Segmental colitis; Colon diverticulosis; Qualitative meta-analysis; Tumor necrosis factor. Abbreviations: Segmental Colitis Associated with Diverticulosis (SCAD); Ulcerative Colitis (UC); Crohn's Disease (CD); Qualitative Meta-Analysis (QMA); Tumor Necrosis Factor-α (TNF-α). Background/Aims: Segmental colitis associated with colonic diverticulosis is a new and emerging entity. We systematically evaluated 486 cases of ...
Gregg Richard E - - 2012
BACKGROUND: Interpretation of a patient's 12-lead ECG frequently involves comparison to a previously recorded ECG. Automated serial ECG comparison can be helpful not only to note significant ECG changes but also to improve the single-ECG interpretation. Corrections from the previous ECG are carried forward by the serial comparison algorithm when ...
Roifman Idan - - 2012
BACKGROUND: Aortic coarctation (CoA) is reported to predispose to coronary artery disease (CAD). However, our clinical observations do not support this premise. Our objectives were to describe the prevalence of CAD among adults with CoA and to determine if CoA is an independent predictor of CAD or premature CAD. METHODS ...
de Tommaso Marina - - 2012
Serum levels of N-acetyl-aspartate (NAA) may be considered a useful marker of neuronal functioning. We aimed to measure serum NAA in cohorts of migraine and tension-type headache patients versus controls, performing correlations with main clinical features. A total of 147 migraine patients (including migraine without aura, with aura and chronic ...
Luijendijk Paul - - 2012
AIMS: Aortic coarctation (CoA) occurs as a "simple" isolated disorder, and in a more "complex" form, combined with associated congenital cardiac abnormalities. Long term outcome of all CoA patients may be complicated by dilatation of the thoracic aorta. The aim of this study was to quantify progressive aortic dilatation, and ...
Parkes Julie - - 2012
Alcoholic liver disease (ALD) is a significant cause of death and morbidity. Detection of liver fibrosis at an early stage could provide opportunities for more optimal management. Serum markers of liver fibrosis offer an alternative to biopsy. Evidence of the performance of biomarkers in ALD is needed and a systematic ...
Braun Niko - - 2012
The two most relevant pathologies of long-term peritoneal dialysis (PD) are simple sclerosis and encapsulating peritoneal sclerosis (EPS). The histological differentiation of those two entities is difficult. The Aim of the study was to establish a method to standardize and facilitate the differentiation between simple sclerosis and EPS METHODS: We ...
LaDisa John F JF - - 2011
Treatments for coarctation of the aorta (CoA) can alleviate blood pressure (BP) gradients (Δ), but long-term morbidity still exists that can be explained by altered indices of hemodynamics and biomechanics. We introduce a technique to increase our understanding of these indices for CoA under resting and nonresting conditions, quantify their ...
Di Salvo Giovanni - - 2011
Aims: To evaluate if obesity has an additional negative impact on left ventricular (LV) geometry and function in normotensive pediatric patients >12 months after successful treatment of aortic coarctation (CoA). Methods and Results: We studied 40 CoA patients (mean age 14 ± 3 years, and male sex 70%), of them ...
Zhang Peng - - 2011
Excessive keratinocyte proliferation is thought to be responsible for the formation and development of psoriasis vulgaris. Evidence indicates that epigenetic modifications are associated with aberrant gene expression, however, nothing is known about the status of histone modifications in psoriasis vulgaris. We investigated alterations in histone modifications in patients with psoriasis ...
Desalegn Biruck - - 2011
This was a screening study that aimed to determine the presence of nephrotoxic mycotoxins in urine samples from patients with chronic kidney disease of uncertain etiology in the North Central Province of Sri Lanka. The percentage detection of aflatoxins, ochratoxins and fumonisins in 31 patients were 61.29%, 93.5% and 19.4%, ...
Huang Yun - - 2011
Objective: This systematic review evaluates the clinical utility of a novel biomarker kidney injury molecule 1 (Kim-1) in the prediction, diagnosis and prognosis of acute kidney injury (AKI). Methods: We searched literature in electronic databases from January 2002 to December 2009 by the key words "kidney injury molecule 1" or ...
Schlensak Christian - - 2011
BACKGROUND: Adequate pump flow is a prerequisite for recovery of end-organ failure and outcome in patients treated with a biventricular assist device (BiVAD). We hypothesized that hemodynamics and organ recovery would improve after biventricular, apical cannulation compared with right atrial cannulation. METHODS: Between 2003 and 2009, we treated 31 patients ...
Sriramnaveen Parvathina - - 2011
Abstract Incidence of acute kidney injury (AKI) in patients with pyogenic liver abscess is rare. In our study we found AKI in 32.6% of patients with liver abscess. Majority of the patients were in their fifties and sixties. As per acute kidney injury network trial criteria, renal failure was in ...
Gono Takahisa - - 2011
The aim of this study was to evaluate neurological manifestations of primary Sjögren’s syndrome (pSS) and investigate the etiology and pathogenesis of peripheral and central nervous complications in pSS. Thirty-two patients with pSS were enrolled in the present study, 20 of whom had neurological involvement plus sicca symptoms. The clinical ...
Coskun Ugur - - 2011
Chronic kidney disease (CKD) is associated with increased risk of cardiovascular disease and death. We evaluated the association between CKD and severity of coronary artery stenosis by calculating SYNTAX Score in patients with left main coronary artery and/or 3-vessel coronary artery disease. Coronary angiograms of 217 patients were assessed. Chronic ...
Brodsky Sergey V - - 2011
An acute increase in the international normalized ratio (INR; a comparison of prothrombin time to monitor the effects of warfarin) over 3 in patients with chronic kidney disease (CKD) is often associated with an unexplained acute increase in serum creatinine (SC) and an accelerated progression of CKD. Kidney biopsy in ...
Majeed Al-Razzuqi Rafi A - - 2011
Few studies have been done on the relation between acetylator status and allergic diseases. To determine any possible association between acetylating phenotype in pediatric patients with atopic dermatitis (AD) and the disease prognosis. Thirty-six pediatric patients and forty two healthy children as a control group were participated in the study. ...
Wu Vin-Cent - - 2011
BACKGROUND: Kidney impairment is noted in primary aldosteronism (PA), and probably initiated by glomerular hyperfiltration. METHODS: A prospectively defined survey was conducted of 602 patients who were suspected of PA in the multiple-center Taiwan Primary Aldosteronism Investigation (TAIPAI) database. Estimated glomerular filtration rate (eGFR) was calculated and followed up at ...
Recio-Mayoral Alejandro - - 2011
BACKGROUND: Cardiovascular morbidity and mortality are high in chronic kidney disease (CKD) patients compared to the general population. Systemic inflammation may contribute to endothelial dysfunction and accelerated atherosclerosis in CKD patients. We assessed the relationship among, endothelial dysfunction, early atherosclerosis and inflammation in predialysis, dialysis and post kidney-transplantation CKD patients. ...
Gakhar Bhavna - - 2011
Acute kidney injury (AKI) is common in patients with multiple myeloma (MM), most commonly caused by cast nephropathy resulting from precipitation of free light chains (FLC) in renal tubules. AKI may be irreversible and require dialysis and predicts a poor prognosis. Reduction in serum FLC concentration is thought to be ...
Modrall J Gregory - - 2011
The purpose of the current study was to identify clinical and kidney morphologic features that predict a favorable blood pressure (BP) response to renal artery stenting (RAS). The study cohort consisted of 149 patients who underwent primary RAS over 9 years. Patients were categorized as "responders" based on modified American ...
Nakaya Izaya - - 2011
Aim:  Hyperuricemia is associated with chronic kidney disease (CKD) progression and cardiovascular events (CVE). In a US study, only 4% of rheumatologists initiated urate-lowering therapy in patients with asymptomatic hyperuricemia (AHU). The present study aimed to clarify how Japanese board-certified nephrologists manage AHU in CKD patients. Methods:  Questionnaires on management ...
Fructuoso M - - 2011
Background: The evaluation of health-related quality of life (QOL) in chronic kidney disease intends to quantify its consequences, according to the patient’s subjective perception. Aim: To evaluate the health-related QOL in four groups of patients followed at our Nephrology Department: chronic kidney disease (CKD) stages 1-4, kidney transplant (KT), haemodialysis ...
Akizawa Tadao - - 2011
BACKGROUND: Anemia is a factor that affects the outcome of patients with chronic kidney disease (CKD); however, there are only a few reports on the management of anemia in Japanese patients with CKD who are not on dialysis. METHODS: We investigated the prevalence, related factors and management of anemia in ...
Xu Jing - - 2011
Objective. Recent studies have identified chronic kidney disease (CKD) as an important risk factor for vasculopathies. While the link between CKD and cardiovascular events is well established, the link with cerebrovascular lesions (CVL) has been less well described. METHODS: We studied the prevalence and prognostic importance of CKD in 1014 ...
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