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Hsiao P P Department of Physical Medicine and Rehabilitation, Wan Fang Hospital, Taipei MedicalUniversity (Hsiao, Hsu, YN Lin, Yu Lin, Chang), Taipei, Taiwan - - - 2014
Patients with physical disabilities more often have median neuropathies of the wrist and more than 70% of wheelchair users are overweight or obese. To explore the effects of body composition on the occurrence of distal median neuropathy and to search for the best probabilistic cutoff value of indicators to predict ...
Nyklíček Ivan I Center of Research on Psychology in Somatic disease (CoRPS), Department of Medical and Clinical Psychology, Tilburg University, The Netherlands. Electronic address: - - 2014
Mindfulness may diminish effects of adversities on psychological well-being in medical patients, but studies are scarce, especially in patients with rheumatoid arthritis (RA). The purpose was to examine the prospective moderating effect of mindfulness regarding psychological distress associated with disease activity and disability in patients with RA. Two-hundred-and-one patients with ...
Fernandez-Flores Angel A Dermatopathologist. Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, - - 2014
Penile amyloidosis has been reported on many occasions in the literature, but all of these have been forms of primary cutaneous amyloidosis. Systemic amyloidosis presenting with a penile ulcer as the first manifestation has not previously been reported. We present two patients in whom an ulcer of the glans penis ...
Szymanski Filip M FM Department of Cardiology, Medical University of Warsaw, 1A Banacha Street, Warsaw, 02-097, Poland, - - 2014
Assessment of stroke risk and implementation of appropriate antithrombotic therapy is an important issue in atrial fibrillation patients. Current risk scores do not take into consideration the comorbidities associated with elevated thromboembolic like obstructive sleep apnea (OSA). The aim of the study was to establish whether atrial fibrillation patients with ...
Schricker Amir A AA Department of Medicine/Cardiology, University of California San Diego Medical Center, San Diego, CA, 92161, - - 2014
Atrial fibrillation (AF) is the most common arrhythmia targeted by catheter ablation. Despite significant advances in our understanding of AF, ablation outcomes remain suboptimal, and this is due in large part to an incomplete understanding of the underlying sustaining mechanisms of AF. Recent developments of patient-tailored and physiology-based computational mapping ...
Berisso Massimo Zoni MZ aDepartment of Cardiology, Padre Antero Micone Hospital, Genova-Sestri Ponente bANMCO Research Center, Florence cDepartment of Internal Medicine, Buon Consiglio FBF Hospital, Napoli dDepartment of Internal Medicine, Presidio Ospedaliero, Osimo eDepartment of Cardiology, AORN Cardarelli, Napoli fDepartment of Cardiology, San Gerardo Hospital, Monza gDepartment of Internal Medicine, Pinerolo Hospital, Pinerolo hDepartment of Cardiology, Maggiore Hospital, Bologna, - - 2014
To provide insights on the antiarrhythmic management of atrial fibrillation among patients enrolled in the Antithrombotic Agents in Atrial Fibrillation (ATA-AF) study, and to assess the adherence of the Italian cardiologists and internists to guidelines recommendations. The ATA-AF study is a multicenter, observational study with prospective data collection on the ...
Falsetti Lorenzo L aInternal and Sub-Intensive Medicine Department, A.O.U. 'Ospedali Riuniti', Ancona, Italy bDepartment of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy cDepartment of Internal Medicine, Ospedale 'S.S. Benvenuti e Rocco', Osimo (Ancona), - - 2014
In hemodynamically stable patients, mortality and morbidity related to atrial fibrillation are mainly due to cardioembolic disorder. No difference in the survival rate and incidence of embolic events has been described in patients undergoing rhythm or rate control if the latter is combined with an appropriate anticoagulant therapy. CHA2DS2-VASc is ...
Browne Sandra D SD Saba University, School of Medicine , 27 Jackson Road Suite 301, Devens, MA 01434 , - - 2014
Introduction: End-stage renal disease (ESRD) and atrial fibrillation are increasingly common concurrent findings among many patients. Coexisting ESRD and atrial fibrillation can further exacerbate each disease process; thus, evidence-based medicine protocols are needed for the treatment of patients with both ESRD and new-onset atrial fibrillation to clarify the appropriate anticoagulant ...
Roman Crina C Crina Roman, Dan L Dumitrascu, Division of Internal Medicine, Second Medical Clinic, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, - - 2014
To analyze the potential relationship between gastroesophageal reflux disease (GERD) and the development of atrial fibrillation (AF). Using the key words "atrial fibrillation and gastroesophageal reflux", "atrial fibrillation and esophagitis, peptic", "atrial fibrillation and hernia, hiatal" the PubMed, EMBASE, Cochrane Library, OVIDSP, WILEY databases were screened for relevant publications on ...
Colucci G G Giuseppe Colucci, MD, Department of Haematology and Central Haematology Laboratory, University Hospital Inselspital, Freiburgstr. 10, 3010 Bern, Switzerland, Tel. +41/31/632 02 64, Fax +41/31/632 34 06, - - 2014
Immunoglobulin light chain (AL) amyloidosis is a systemic disease caused by a plasma cell clone synthesizing an unstable light chain, which forms amyloid fibrils. Deposition of amyloid fibrils affects primarily kidney, heart, nervous system, spleen, liver, gastrointestinal tract and the skin. Skin bleeding in these patients is called amyloid purpura. ...
Sanna Tommaso T From the Catholic University of the Sacred Heart, Institute of Cardiology (T.S.), and Institute of Neurology, Campus Bio-Medico University (V.D.L.) - both in Rome; the Department of Neurology and Stroke Center, University Hospital Essen, Essen (H.-C.D.), and Hospital Klinikum Coburg, Teaching Hospital of the University of Würzburg, Coburg (J.B.) - both in Germany; Bluhm Cardiovascular Institute (R.S.P.) and Davee Department of Neurology (R.A.B.), Northwestern University Feinberg School of Medicine, Chicago; Population Health Research Institute, McMaster University, Hamilton, ON, Canada (C.A.M.); University of Kansas Medical Center, Kansas City (M.M.R.); the KU Leuven Department of Neurosciences, the VIB-Vesalius Research Center, and the Department of Neurology, University Hospitals Leuven - all in Leuven, Belgium (V.T.); Medtronic, Mounds View, MN (T.R., K.L.); and Medtronic, Maastricht, the Netherlands - - 2014
Current guidelines recommend at least 24 hours of electrocardiographic (ECG) monitoring after an ischemic stroke to rule out atrial fibrillation. However, the most effective duration and type of monitoring have not been established, and the cause of ischemic stroke remains uncertain despite a complete diagnostic evaluation in 20 to 40% ...
Gurger Mehtap M aDepartment of Emergency bDepartment of Cardiology cDepartment of Cardiovascular Surgery, Elazig Education and Research Hospital dDepartment of Biochemistry, Firat University Medical Faculty, Elazig, - - 2014
Our aim was to investigate the apelin-12 levels in patients with atrioventricular tachyarrhythmias and compare with those in patients with lone atrial fibrillation. Forty four patients with supraventricular tachycardia as atrial fibrillation, 44 patients with paroxysmal supraventricular tachycardia (P-SVT) as atrioventricular tachyarrhythmias, including atrioventricular nodal reentrant tachycardia or atrioventricular reentrant ...
Reinecke Holger H Division of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital of Muenster, Muenster, - - 2014
Chronic kidney disease (CKD) is associated with increased cardiovascular morbidity and mortality but there are few studies available about atrial fibrillation, the most frequent arrhythmia in CKD, and the applied treatment. Based on the prospective German Competence NETwork on Atrial Fibrillation, data of 3138 patients with atrial fibrillation were analyzed ...
Hankey Graeme J GJ School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, - - 2014
Each year, 1·0-2·0% of individuals with atrial fibrillation and 0·1-0·2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0·2-0·5% of individuals with atrial fibrillation who are receiving one of the ...
Hersi Ahmad A 1Department of Cardiac Sciences, King Saud University, Riyadh, Saudi - - 2014
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The Saudi Atrial Fibrillation Survey registry was designed to provide epidemiological and clinical data on patients with AF. The registry included 400 consecutive patients who met the eligibility criteria. Control of AF at the time of the initial visit was ...
Lin Andrew H AH aDepartment of Cardiology bDepartment of Internal Medicine, Naval Medical Center San Diego cDepartment of Cardiology, University of California San Diego, San Diego, California, - - 2014
Atrial fibrillation is the most common cardiac arrhythmia, and age is a well-established independent risk factor for stroke in these patients. Whereas high-risk patients clearly benefit from anticoagulation to prevent stroke, less is known about how to treat low-risk patients. Despite the recent guidelines and studies demonstrating no benefit and ...
Laranjo Sérgio S Instituto de Fisiologia, Faculty of Medicine of Lisbon, Av Prof Egas Moniz, Lisbon, Portugal; Cardiovascular Autonomic Function Lab, Faculty of Medicine of Lisbon, Av Prof Egas Moniz, Lisbon, Portugal. Electronic address: - - 2014
We report a case of a patient with recurrent syncope and paroxysmal atrial fibrillation whose clinical status greatly improved after a period of orthostatic training. The potential efficacy of this non-pharmacological measure in modulating the autonomic tone is discussed below.
Brown Richard A RA University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Cardiovascular Medicine , Birmingham , - - 2014
Introduction: Intravenous vernakalant (Brinavess) has been developed and approved in Europe as a safe and efficacious drug to rapidly convert recent onset atrial fibrillation to sinus rhythm in patients with no minimal or structural heart disease. Areas covered: The pharmacology of vernakalant and the pivotal Phase II and III clinical ...
Granger Christopher B CB Duke Clinical Research Institute, Durham, - - 2014
Approximately 430,000 patients were receiving maintenance dialysis in the United States in 2011(1). Compared to the general population, atrial fibrillation is far more common(2) and associated with a much higher risk of stroke in the dialysis population(3). Thus, there is an important need to define and apply strategies to reduce ...
Gu Ya-Jun YJ School of Medical Laboratory, Tianjin Medical University, Tianjin 300203, China; Department of Clinical Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China; Department of Clinical Laboratory, Tianjin Children's Hospital, Tianjin 300074, - - 2014
Objective: Our aim was to investigate clinical and laboratory characteristics of osteoarthritic patients who had amyloid deposition in their knee joints. Methods: Synovial membranes were obtained from 36 patients with knee osteoarthritis (OA) who underwent joint replacement surgery. From this sample, the diagnosis of amyloid was determined by Congo red ...
Min T T ST4 Diabetes and Endocrinology Princess of Wales Hospital Bridgend, CF31 1RQ - - 2014
Thyroid storm is a rare but potentially life-threatening complication of hyperthyroidism. Early recognition and prompt treatment are essential. Atrial fibrillation can occur in up to 40% of patients with thyroid storm. Studies have shown that hyperthyroidism increases the risk of thromboembolic events. There is no consensus with regard to the ...
Poulsen Keld - - 2014
Transthyretin (TTR), an abundant protein in cerebrospinal fluid (CSF), contains a free, oxidation-prone cysteine residue that gives rise to TTR isoforms. These isoforms may reflect conditions in vivo. Since increased oxidative stress has been linked to neurodegenerative disorders such as Alzheimer's disease (AD) it is of interest to characterize CSF-TTR ...
Ahrens Ingo I Heart Center, University of Freiburg, Department of Cardiology and Angiology I, Freiburg, - - 2014
The direct factor Xa inhibitor rivaroxaban was the first within the group of orally available direct factor Xa inhibitors to gain clinical approval for oral anticoagulation in patients with nonvalvular atrial fibrillation in 2011. The -xabans, as drugs from the group of oral direct factor Xa inhibitors are often referred ...
Camm A John AJ Division of Clinical Sciences, St George's, University of London, London, - - 2014
Atrial fibrillation (AF) is associated with a fivefold increase in the risk of stroke. The Phase III ROCKET AF (Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) trial showed that rivaroxaban, an oral, direct Factor Xa ...
Min Ju-Hong JH Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Patients with autoimmune disorders often have low levels of 25-hydroxyvitamin D [25(OH)D3], which correlates with disability or disease activity. Vitamin D may play a role in neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD), as an important factor involved in immunological pathways. We investigated the relationship between vitamin D levels ...
Bang Casper N CN aDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA bDepartment of Cardiology, The Heart Center, Rigshospitalet, Copenhagen cDepartment of Medicine, Glostrup University Hospital, Glostrup, Denmark dDepartment of Dermatology, Tuffs Medical Center, Boston, Massachusetts, - - 2013
Inflammation contributes to the pathogenesis of psoriasis as well as atrial fibrillation. The impact of psoriasis and its association with new-onset atrial fibrillation was assessed in hypertensive patients with left ventricular hypertrophy (LVH). The predictive value of baseline or incident psoriasis for new-onset atrial fibrillation was evaluated in 7099 hypertensive ...
Chow Grant V - - 2013
Catheter ablation for atrial fibrillation (AF) has become a widely accepted therapy for appropriate patients, typically those with AF that is highly symptomatic and refractory to therapy with anti-arrhythmic medications. This article is protected by copyright. All rights reserved.
Baturova M A - - 2013
We assessed the prevalence of atrial fibrillation (AF) prior to first-ever ischemic stroke by examining a comprehensive electronic ECG archive. The study sample comprised 336 consecutive stroke patients (median age 76 (IQ16) y, 200 men) enrolled in Lund Stroke Register from March 2001 to February 2002 and 336 age- and ...
Boulé Stéphane - - 2013
We report the case of a very prolonged spontaneous episode of self-terminating ventricular fibrillation in a patient with Brugada syndrome (BrS). The patient first underwent implantation of an internal loop recorder after an episode of prolonged loss of consciousness (several minutes) that was suggestive of a nonarrhythmic cause. After a ...
Cögen Etem Emre EE Department of Neurology, Faculty of Medicine, Yuzuncu Yil University, Van, - - 2013
To investigate the impact of atrial fibrillation on mortality and morbidity in ischaemic stroke patients. The retrospective study was conducted at the Neurology Clinic, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey, and comprised records of ischaemic stroke patients hospitalised between January 2006 and September 2009. SPSS 13 was used ...
Wagh Kunal - - 2013
Atrial fibrillation is the most common type of arrhythmia in adults. Atrial fibrillation occurs as paroxysms or may become established as permanent condition. Patients with atrial fibrillation are at increased risk for thromboembolic disease. To study effectiveness of Warfarin in reducing Stroke incidence in patients of Atrial Fibrillation. This hospital ...
De Decker Laure L Pôle Hospitalo-Universitaire de gérontologie clinique, CHU Nantes, - - 2013
The atrial fibrillation (AF) is one of the most important cause of arythmia and cerebrovascular disease in clinical practice. Comorbidity is defined as the association of active chronical diseases and a target disease. comparison between burden illness of the patients in interventional (n=4) and observational studies, form Medline database (n=4), ...
Johnsen Søren Paaske - - 2013
Preadmission oral anticoagulant treatment (OAT) has been linked with less severe stroke and a better outcome in patients with atrial fibrillation. However, the existing studies have methodological limitations and have, with one exception, not included hemorrhagic strokes. We performed a nationwide historic follow-up study using data from population-based healthcare registries ...
Chang Chia-Hsuin CH Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Department of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, - - 2014
To contain cost, Taiwan's previous National Health Insurance Reimbursement Policy requested that physicians discontinue their patients' statin therapy once the serum cholesterol had reached appropriate levels. This allowed us to evaluate the association between statin continuation and the occurrence of atrial fibrillation/flutter and whether it was modified by chronic kidney ...
Armstrong April W - - 2013
Psoriasis patients have an increased incidence of cardiovascular disease. Atrial fibrillation is the most common cardiac arrhythmia and is associated with increased morbidity and risk of stroke. In this study, we assessed the association between psoriasis, electrocardiographic characteristics, and incident atrial fibrillation. Two cohorts were studied to address this question. ...
Själander Sara - - 2013
Oral anticoagulation is the recommended treatment for stroke prevention in patients with atrial fibrillation. Notwithstanding, many patients are treated with acetylsalicylic acid (ASA) as monotherapy. Our objective was to investigate if atrial fibrillation patients benefit from ASA as monotherapy for stroke prevention.METHODS AND RESULTS: Retrospective study of patients with a ...
Kaitani Kazuaki - - 2013
Intravenous adenosine triphosphate (ATP) administration could reveal dormant conduction (DC) gaps on the ablation line of a pulmonary vein isolation (PVI). We compared the ATP-provoked DC sites in the initial PVI with the PV re-conduction sites in the second session in patients with paroxysmal atrial fibrillation (AF).METHODS AND RESULTS: We ...
Tomita Hideharu - - 2013
Effectiveness and safety of warfarin therapy for non-valvular atrial fibrillation (NVAF) patients are strongly associated with its stability presented such as time in therapeutic range (TTR) of PT-INR. However, the factors that affect TTR have not been fully elucidated in Japan where majority of patients are controlled within the range ...
Cleland John G F - - 2013
Remarkably little evidence exists that cardiac resynchronization therapy (CRT) is effective in patients who have atrial fibrillation (AF) but who otherwise seem suitable for this treatment. The landmark trials of CRT generally excluded patients with AF because atrioventricular (AV) resynchronization was considered a possibly important mechanism by which CRT might ...
Mizrahi E H - - 2013
The purpose of this study was to evaluate whether atrial fibrillation affects the short-term functional outcome of elderly patients with ischemic stroke, undergoing post-acute in-hospital rehabilitation. We studied 919 consecutive patients admitted for ischemic stroke rehabilitation, out of whom 19.6% were diagnosed with atrial fibrillation. The Functional outcome of atrial ...
Pujol Lereis Virginia A - - 2013
Atrial fibrillation is the most common cause of embolic stroke associated to heart disease. Oral anticoagulation with vitamin K antagonists substantially reduces this risk. We assessed a group of patients with prior diagnosis of atrial fibrillation who sustained an ischemic stroke while receiving an adequate regime of oral anticoagulation. We ...
Juma Salima - - 2013
Warfarin prescribing patterns for hemodialysis patients with atrial fibrillation vary widely amongst nephrologists. This may be due to a paucity of guiding evidence, but also due to concerns of increased risks of warfarin use in this population. The literature lacks clarity on the balance of warfarin therapy between prevention of ...
Hankey Graeme J - - 2013
Three novel oral anticoagulants (NOACS)-dabigatran etexilate, rivaroxaban, and apixaban-have been approved in many countries for stroke prevention in atrial fibrillation, because they are associated with the same or lower rates of stroke, bleeding (particularly intracranially) and death compared with warfarin; and unlike warfarin, they can be given in fixed doses ...
Ghanny Shari - - 2013
To summarize data relevant to novel oral anticoagulants (nOACs), mainly apixaban, dabigatran and rivaroxaban, as alternatives to vitamin K antagonists (VKAs). RE-LY was the first contemporaneous study to compare a nOAC, dabigatran, with dose-adjusted warfarin, for prevention of stroke and systemic embolism in atrial fibrillation. Since then multiple studies have ...
Nelson Winnie W - - 2013
This study determined the association between co-morbidities, including heart failure (HF) and time in therapeutic range (TTR), in patients with nonvalvular atrial fibrillation. Longitudinal patient-level anticoagulation management records collected from 2006 to 2010 were analyzed. Adult patients with nonvalvular atrial fibrillation who used warfarin for a 12-month period with no ...
Breuer Lorenz - - 2013
An obese man (BMI, 44.7) with atrial fibrillation who was receiving dabigatran for thromboprophylaxis presented with an ischemic stroke. Dabigatran levels during observed administration were less than the 25th percentile of the therapeutic trough level.
Takanashi Tetsuo - - 2013
Abstract Objective: To investigate histological features of deposited amyloid in the synovial tissue and its clinical significance in knee joint osteoarthritis (OA) patients. Methods: We prospectively enrolled 232 consecutive patients who underwent arthroplasty or total replacement of the knee joint for treatment of OA. Congo red staining and immunohistochemistry were ...
Ihse Elisabet - - 2013
Abstract The clinical phenotype of familial ATTR amyloidosis depends to some extent on the particular mutation, but differences exist also within mutations. We have previously described that two types of amyloid fibril compositions exist among Swedish ATTRV30M amyloidosis patients, one consisting of a mixture of intact and fragmented ATTR (type ...
Keating Gillian M - - 2013
The direct factor Xa inhibitor apixaban (Eliquis(®)) has predictable pharmacodynamics and pharmacokinetics and does not require routine anticoagulation monitoring. This article reviews the efficacy and tolerability of oral apixaban to reduce the risk of stroke or systemic embolism in patients with nonvalvular atrial fibrillation (AF). In the ARISTOTLE (Apixaban for ...
Ertas Faruk - - 2013
Aims; This study aims to evaluate stroke risk in non-valvular atrial fibrillation (AF) and anticoagulant drug utilization within conformity to AF guidelines. AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) is a prospective, multicentre study designed with the aim of describing the prevalence and epidemiology of AF practice in Turkey.Methods; Patients ...
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