Search Results
Results 401 - 450 of 1656
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Kocaman Sinan Altan - - 2008
Monocytes have been shown to take an important role in collateral growth in animal studies. The aim of the study was to investigate the relation of circulating monocyte count with collateral development in patients with severely stenotic CAD. Patients who had > or =95% stenosis in at least one major ...
Park J-W - - 2008
Despite the proven clinical efficacy of phosphodiesterase inhibitors in the treatment of erectile dysfunction (ED), some patients do not respond to the medication. By means of nailfold capillary microscopy in patients with concomitant coronary artery disease (CAD) and ED, it was evaluated whether the extent of microvascular dysregulation predicts the ...
Herlitz Johan - - 2008
OBJECTIVES: To describe the characteristics and outcome of patients with acute myocardial infarction (AMI) in a community, with particular emphasis on those who never reached a Coronary Care Unit (CCU) and those in whom the primary diagnosis was something other than a heart attack. METHODS: Patients hospitalised in the city ...
Bestetti Reinaldo B - - 2008
We sought to determine clinical characteristics as well as outcome of angina-free patients with chronic ischemic heart failure. In comparison with ischemic chest pain patients, angina-free patients have higher heart rate and systolic blood pressure on admission, lower number of diseased coronary artery vessels at coronary arteriogram and higher survival ...
Ahmar Walid - - 2008
A minority of patients presenting with ST elevation myocardial infarction (STEMI) have angiographically normal coronary arteries. We aimed to assess its incidence, identify possible aetiologies and determine long-term prognosis. We retrospectively analysed 714 consecutive patients presenting with STEMI over a 10-year period (1995 to 2005), and identified 41 patients with ...
Bainey Kevin R - - 2008
OBJECTIVE: In-stent restenosis (ISR) remains an important problem following percutaneous coronary intervention (PCI). Although it is generally believed that patients with ISR present with stable angina, this has not been well characterized. The aim of this study was to define the incidence, predictors, timing and clinical presentation of patients with ...
Pontone G - - 2007
AIM: To investigate the clinical impact of multidetector computed tomography (MDCT) in patients with a low versus a high pre-test likelihood of coronary artery disease (CAD). MATERIALS AND METHODS: A cohort of 120 patients with suspected CAD, scheduled for conventional coronary angiography, underwent MDCT. Using the American Heart Association (AHA)/American ...
Wackers Frans J Th - - 2007
OBJECTIVE: The purpose of this study was to assess whether the prevalence of inducible myocardial ischemia increases over time in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: Participants enrolled in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study underwent repeat adenosine-stress myocardial perfusion imaging 3 years after ...
Nurkalem Z - - 2007
The aim of the present study was to investigate degree of erectile dysfunction (ED) in males with slow coronary flow (SCF). Endothelial dysfunction was proposed to be the underlying mechanism in both diseases. A total of 29 male patients with slow coronary flow (mean age 45+/-7 years) and 23 male ...
Touzé Emmanuel - - 2007
BACKGROUND: The risk of coronary artery disease (CAD) is traditionally considered high in patients who had an ischemic stroke or a transient ischemic attack (TIA). However, few studies have specifically assessed the absolute risk of coronary events in those patients and predictors of such events are not well known. SUMMARY ...
Soltesz Pal - - 2007
The aim was to measure the level of antibodies to oxidized LDL (oxLDL) and C-reactive protein (CRP) in the serum of patients with acute coronary syndrome (ACS). The results were correlated with data obtained from patients with stable coronary artery disease (stable CAD) and healthy controls. Thirty-three patients with ACS ...
Bhardwaj R - - 2007
BACKGROUND: Chest pain is a common emergency. Some patients have dynamic ECG changes with chest pain. Purpose of study was to find out the incidence of coronary artery disease (CAD) in patients presenting with chest pain and dynamic ECG changes. MATERIAL AND RESULTS: Seventy two patients presenting with chest pain ...
Nishijima Tsunenori - - 2007
OBJECTIVE: We previously found a -786T/C polymorphism in the 5'-flanking region of the endothelial nitric oxide synthase (eNOS) gene and reported that this polymorphism is strongly associated with coronary spasm. In this study, we examined whether the polymorphism is a prognostic marker in coronary spasm patients. METHODS AND RESULTS: We ...
Giansante Carlo - - 2007
OBJECTIVES AND METHODS: The present study was designed to evaluate the role of some inflammation [interleukin (IL)-1beta, soluble IL-1 receptor, IL-1 receptor antagonist (IL-1RA), high-sensitivity C-reactive protein (hsCRP) and fibrinogen], and remodeling markers [matrix metalloproteinase (MMP)-9, tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2] in patients with acute coronary syndrome (ACS; ...
de Vries Jessica - - 2007
OBJECTIVES: To investigate the incidence and angiographic predictors of functional collateral perfusion in patients with stable coronary artery disease, scheduled for elective PCI. BACKGROUND: Functional collateral perfusion is defined as a Pw/Pa ratio>or=0.24. Since this can only be measured intracoronary, it is important to investigate baseline clinical and angiographic predictors ...
Scholte A J H A - - 2008
OBJECTIVE: The purpose of the study was to evaluate the prevalence of CAD as well as plaque morphology in asymptomatic patients with type 2 diabetes using multi-slice computed tomography (MSCT). In addition, the relation between calcium score and MSCT findings was explored. DESIGN: In 70 patients, coronary calcium scoring and ...
Leber Alexander W - - 2007
AIMS: The aim of the present study was to assess the clinical performance of a dual X-ray source multi-slice CT (MSCT) with high temporal resolution to assess the coronary status in patients with an intermediate pretest likelihood for significant coronary artery disease (CAD) without using negative chronotropic pretreatment. METHODS AND ...
Undas Anetta - - 2008
BACKGROUND: Stable angina is associated with unfavorable fibrin structure/function. It is not known how acute coronary syndromes (ACS) affect fibrin architecture. OBJECTIVE: We investigated fibrin clot properties and their determinants in ACS patients. PATIENTS AND METHODS: Clot permeability, turbidity and fibrinolysis were assessed in 40 patients with ACS versus 40 ...
Cruz-Gonzalez Ignacio - - 2008
BACKGROUND: There is limited experience with the use of argatroban in combination with glycoprotein IIb/IIIa (GPIIb/IIIa) inhibitor in acute coronary syndrome (ACS) patients with heparin-induced thrombocytopenia (HIT) undergoing percutaneous coronary intervention (PCI). MATERIALS AND METHODS: This single-center, retrospective study evaluated the efficacy (composite of death, myocardial infarction, or urgent revascularization) ...
V Korn Hubertus - - 2007
OBJECTIVE: A visible thrombus remains a risk factor during percutaneous coronary intervention (PCI). METHODS: Between October 2004 and March 2005, we treated all patients who consecutively presented with acute coronary syndrome + angiographically visible thrombus using the Export Aspiration System (group 1, n = 79). We retrospectively analyzed all consecutive ...
Zdzienicka Joanna - - 2007
BACKGROUND: Lack of chest pain or atypical pain does not exclude acute coronary syndrome (ACS). AIM: To assess demographic and clinical characteristic as well as treatment strategies in patients with atypical chest pain on admission in hospitals without on-site invasive facility (IF). METHODS: Twenty-nine community hospitals participated in the Registry ...
Lukkarinen Hannele - - 2007
BACKGROUND: Cardiovascular diseases are currently the leading cause of death worldwide. In addition to risk factor prevention, the treatment interventions of coronary artery disease (CAD) include medication, percutaneous transluminal coronary angioplasty (PTCA) with stenting, and coronary artery bypass grafting (CABG). Patients with CAD have a more than twofold risk of ...
Sobieszczanska Malgorzata - - 2007
OBJECTIVE: Body surface potential mapping (BSPM) is essentially recommended for detecting and evaluating abnormalities of cardiac electric field specific for various stages of ischemic state of myocardium caused by coronary artery disease (CAD). In this regard, a goal of the present paper was to summarize the BSPM results, which were ...
Bereczky Zsuzsanna - - 2008
INTRODUCTION: The effect of factor XIII A subunit (FXIII-A) Val34Leu polymorphism on the risk of coronary artery disease (CAD) has been extensively studied. In this study we investigated how FXIII-A Val34Leu genotypes influence plasma factor XIII levels in patients with coronary sclerosis (CS) and myocardial infarction (MI) and how fibrinogen ...
Tsuru R - - 2008
OBJECTIVES: To clarify the role of granzyme B in acute coronary syndrome. DESIGN AND SETTING: Granzyme B is a member of the serine esterase family released from cytotoxic lymphocytes and plays an important role in cellular apoptosis by activating intracellular caspases. Granzyme B expression was compared between patients with stable ...
Song Xian-Tao - - 2007
BACKGROUND: Many studies have examined gender related differences in the presenting symptoms, management and prognosis of patients with acute coronary syndrome (ACS). Much data are available from industrialized countries, in which ACS is a major cause of morbidity and mortality, but relatively little information has been obtained from China, where ...
Adachi T - - 2007
Previous studies have shown that recent activation of the inflammatory response in coronary atherosclerotic lesions contributes to rapid progressive plaque destabilisation. Neopterin, a by-product of the guanosine triphosphate pathway, is produced by activated macrophages and serves as an activation marker for monocytes/macrophages. To elucidate the role of neopterin in coronary ...
Khalique Omar - - 2007
We investigated, in a prospective study of 1,007 patients who underwent coronary angiography for suspected coronary artery disease (CAD), the association of obstructive CAD with severe or moderate decrease in glomerular filtration rate (GFR) calculated from the Modification of Diet in Renal Disease equation. Baseline characteristics were similar in patients ...
Pouleur Anne-Catherine - - 2007
Preoperative identification of significant coronary artery disease (CAD) in patients prior to valve surgery requires systematic invasive coronary angiography. The purpose of this current prospective study was to evaluate whether exclusion of CAD by multi-detector CT (MDCT) might potentially avoid systematic cardiac catheterization in these patients. Eighty-two patients (53 males, ...
Ueda Yasunori - - 2007
OBJECTIVE: Thrombosis caused by disrupted yellow plaque is regarded as a cause of acute myocardial infarction (MI). However, it has not been clarified if young patients have the same pathophysiology as older ones. Therefore, we elucidated clinical and angioscopic characteristics of young patients. METHODS: Among a series of patients (n ...
Yildirim Nesligül - - 2007
OBJECTIVE: In this study we aimed to examine the angiographic findings, traditional risk factors and natural history of Turkish patients <40 and >or=40 years old with coronary heart disease (CHD). METHODS: The records of 491 patients with stable angina pectoris or acute coronary syndrome (ACS), who had undergone coronary angiography ...
Ilhan Necip - - 2007
BACKGROUND: As an endogenous inhibitor of nitric oxide production, asymmetric dimethylarginine (ADMA) is reported to be associated with coronary artery disease (CAD). METHODS: We measured plasma levels of ADMA, nitrate + nitrite (NOx), total homocysteine (tHCY), and renal function in 106 people with angiographic evidence of coronary artery disease (CAD), ...
Cesar Luiz A M - - 2007
AIMS: We sought to evaluate the effects of trimetazidine on ischemia induced by dobutamine-atropine stress echocardiography in patients with class I or class II angina. METHODS: In a randomized, double-blind, placebo-controlled study, 66 patients with proved coronary disease were subjected to dobutamine-atropine stress echocardiography. Ischemia was proved in 56 patients ...
Høilund-Carlsen Poul F - - 2007
According to most current guidelines, stable angina pectoris patients with a high probability of having coronary artery disease can be reliably identified clinically. To examine the reliability of clinical evaluation with or without an at-rest electrocardiogram (ECG) in patients with a high probability of coronary artery disease. A prospective series ...
Santangeli Pasquale - - 2008
We assessed heart rate variability (HRV) and high-sensitivity C-reactive protein (CRP) serum levels in 77 patients with chronic stable angina (CSA), 47 of whom had obstructive coronary artery disease (CAD) and 30 normal or near-normal coronary arteries (NCA). The effect of percutaneous coronary interventions (PCI) and bypass surgery (CABG) on ...
Toutouzas Konstantinos - - 2007
OBJECTIVES: The purpose of this study was to investigate the possible correlation between morphologic and functional characteristics of culprit lesions (CL) in patients with acute coronary syndromes (ACS) and chronic stable angina (CSA). BACKGROUND: Intravascular ultrasound (IVUS) provides morphologic assessment and intracoronary thermography (ICT) evaluates the local inflammatory activation of ...
Phillips Sabrina Deann - - 2007
We examined body mass index (BMI) in kilograms divided by height in meters squared in 842 patients who underwent coronary angiography for suspected coronary artery disease (CAD) in a 2-month period in 2000 at Baylor University Medical Center. Comparison of the BMI in the 624 patients in whom > or ...
Jeong Young-Hoon - - 2008
BACKGROUND: Higher rates of clinical and angiographic restenosis have been reported after coronary stenting in patients with significant chronic kidney disease (CKD). Whether drug-eluting stents (DES) can reduce long-term clinical events in CKD patients compared with bare metal stents (BMS) has not been established. METHODS: The study enrolled 104 consecutive ...
Choi E-K - - 2007
AIMS: Information on the clinical outcome of patients with diabetes with silent myocardial ischaemia is limited. We compared the clinical and angiographic characteristics, and the clinical outcomes of diabetic patients with asymptomatic or symptomatic coronary artery disease (CAD). METHODS: Three hundred and ten consecutive diabetic patients with CAD were divided ...
Saely Christoph H - - 2007
BACKGROUND: We aimed at investigating serum adiponectin in patients with the metabolic syndrome (MetS), in patients with angiographically diagnosed coronary artery disease (CAD), and in patients who had both, the MetS and CAD. METHODS: We enrolled 687 consecutive patients undergoing coronary angiography for the evaluation of CAD. RESULTS: From our ...
Jguirim-Souissi Imen - - 2007
Several matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have been implicated in the development and outcome of coronary artery disease (CAD). We investigated whether MMP-12 and TIMP-1 levels were associated with risk, severity, and outcome of CAD. Plasma MMP-12 and TIMP-1 levels are measured in 50 and 44 ...
Finimundi Helius C - - 2007
AIM: This study was designed to determine whether therapy with a diuretic has antianginal effects in patients with stable angina who are already treated with a traditional antianginal regimen. METHODS AND RESULTS: Forty patients with chronic stable angina and normal left ventricular function were randomized in a double-blind, placebo-controlled study. ...
Watson Kristin - - 2007
OBJECTIVE: To compare clinical outcomes and glycoprotein IIb-IIIa inhibitor use in patients undergoing percutaneous coronary intervention (PCI) who received bivalirudin or unfractionated heparin (UFH) in a real-world setting. DESIGN: Retrospective cohort analysis. SETTING: University-affiliated medical center. PATIENTS: One thousand seventy-five adult patients who underwent PCI and received either bivalirudin (539 ...
Lanzer Peter - - 2007
AIMS: The aim of this retrospective study was to assess the feasibility of catheter-based interventions in two different vascular beds performed in a single stage in patients with vascular multimorbidity. METHODS AND RESULTS: Fifty patients, 28 males, mean age 68.6 (+/- 9.2) years and 22 females, mean ages 72.2 (+/- ...
Hassan Mustafa - - 2007
BACKGROUND: Reduced left ventricular ejection fraction (LVEF) is a risk factor for poor outcomes in patients with coronary artery disease (CAD). Mental stress-induced myocardial ischemia (MSIMI) also identifies a subset of CAD patients at increased risk for future cardiovascular events. Susceptibility to MSIMI in patients with CAD and reduced LVEF ...
El-Sakka Ahmed - - 2007
INTRODUCTION: Recently it has been demonstrated that enhanced external counterpulsation (EECP) could improve erectile dysfunction (ED) in patients with refractory ischemic heart disease (IHD). AIM: To assess the effect of risk factors on the efficacy and the satisfaction rate of EECP in patients with coronary artery disease (CAD)-associated ED. MAIN ...
Miller Todd D - - 2007
BACKGROUND: The effectiveness of stress single photon emission computed tomography (SPECT) as a gatekeeper for coronary angiography has not been extensively investigated. The characteristics of patients referred for early angiography after a normal stress SPECT study have not been described. METHODS AND RESULTS: Over a 10-year period, 14,273 patients without ...
Cabrera-Bueno Fernando - - 2007
The development of dynamic left ventricular outflow tract (LVOT) obstruction (DLVOTO) during effort in patients without hypertrophic cardiomyopathy has been described only a few times and its clinical significance has not been established. This study was undertaken to determine DLVOTO during exercise in patients with angina and normal coronary arteries, ...
Markou A L P - - 2007
AIM: The aim of this study is to evaluate the influence of coronary artery bypass graft (CABG) on physical activity (PA) one year postoperative and the influence of the preoperative level of PA on the postoperative PA level. METHODS: In 428 patients, mean age 64.1+/-9.2 (30-84), undergoing an isolated CABG ...
Duygu Hamza - - 2008
BACKGROUND: Inflammation is one of the key mechanism in the development and progression of coronary artery disease. Myocardial bridging (MB) increases the tendency for development of atherosclerosis. The role of inflammation on the development of atherosclerosis in the MB is not clear. In this study, we investigated the existence of ...
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