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Results 101 - 150 of 1664
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Kiyosue Arihiro - - 2010
This study examines whether the serum concentration of cystatin C (Cys C) correlates with the severity of coronary artery disease (CAD) and whether it provides additional information on the risk for CAD in patients without chronic kidney disease (CKD) estimated by the creatinine-based glomerular filtration rate (GFR). The relationship between ...
Jenkins S M M - - 2011
Studies have demonstrated considerable accuracy of multi-slice CT coronary angiography (MSCT-CA) in comparison to invasive coronary angiography (I-CA) for evaluating coronary artery disease (CAD). The extent to which published MSCT-CA accuracy parameters are transferable to routine practice beyond high-volume tertiary centres is unknown. To determine the accuracy of MSCT-CA for ...
Manginas Athanassios - - 2010
We sought to evaluate for the first time in humans the safety and feasibility of right ventricular (RV) thermography in patients with coronary artery disease (CAD) and in patients after heart transplantation (Tx), in comparison to subjects without structural heart disease (controls). Ninety-one RV thermography procedures were performed in 16 ...
Eymann Alfredo - - 2010
Benign transient hyperphosphatasemia of infancy (BTH) is a condition characterized by disproportionately high levels of serum alkaline phosphatase (SAP). We report 4 cases of healthy patients with an elevated SAP. The mean age of the patients was 33 (14-52) months, with three females and one male. All children had a ...
Lockie Tim T The Rayne Institute, 3rd Floor Lambeth Wing, St. Thomas' Hospital, KCL, London, SE1 7EH, United Kingdom. - - 2010
Fractional flow reserve (FFR) is an accepted standard to detect the functional significance of coronary stenoses. Recent trials suggest that revascularization of moderate coronary stenoses can be safely deferred if the FFR is > or = 0.75 and FFR can be used to guide therapy in multivessel disease. In a ...
Chow Benjamin J W - - 2010
The accuracy of 64-slice computed tomographic coronary angiography (CTA) and its ability to direct revascularization in patients with acute chest pain syndrome (ACPS) was investigated. A total of 107 patients with ACPS presenting to the emergency department and referred to cardiology were prospectively enrolled and underwent CTA. From the clinical ...
Sairaku Akinori - - 2010
We aimed to evaluate whether there was a difference in the arterial stiffness assessed by the cardio-ankle vascular index (CAVI) between patients with acute coronary syndrome (ACS) and those with stable angina pectoris (SAP). A total of 199 consecutive patients, 79 with ACS and 120 with SAP, who underwent emergency ...
Zembala Marian - - 2010
The aim of this study was to confirm the generalizability of the conclusions of the STICH (Surgical Treatment for Ischemic Heart Failure) trial. Surgical ventricular reconstruction (SVR) added to coronary artery bypass grafting (CABG) did not decrease death or cardiac hospitalization in STICH patients randomized to CABG with (n = ...
Mizukoshi Masato - - 2010
Unstable angina pectoris (UAP) is categorized with the Braunwald classification. However, the association of clinical presentation and plaque structure/function has not yet been elucidated in relation to cause. We used optical coherence tomography to investigate this relation. One hundred fifteen patients with primary UAP were categorized according to the Braunwald ...
Al Badarin Firas J - - 2011
Metabolic syndrome (MetSx) encompasses several risk factors for macrovascular coronary artery disease. An association between MetSx and coronary syndrome X has also been reported, suggesting that patients with MetSx are more likely to have endothelial dysfunction in the setting of angiographically normal coronary arteries. It remains unknown whether MetSx patients ...
Ahmed Waqas - - 2010
Enhanced External Counterpulsation (EECP) has emerged as a promising non-invasive modality not only for patients with refractory angina pectoris (RAP) but also for patients with heart failure. To our knowledge, no published data exists in Pakistan about the benefits of EECP. We report on a case series of 16 consecutive ...
Iwasaki Kohichiro - - 2010
To study the prevalence of noncalcified plaque in asymptomatic low-risk patients with no or mild coronary artery calcium (CAC). From 502 patients with coronary risk factors who underwent 64-slice computed tomography, 224 asymptomatic patients were identified with no CAC (n=117) or mild CAC (n=107; defined as patients with Agatston scores ...
Bendix K - - 2011
(1) To establish the prevalence of incidental extra-cardiac findings (ECFs) in coronary multi detector computed tomography (CCT) performed in a large, homogeneous cohort of patients suspected of coronary artery disease (CAD). (2) To examine whether any association can be established between ECFs and pretest risk as determined by conventional risk ...
Dachman Abraham H - - 2010
To assess the effect of using computer-aided detection (CAD) in second-read mode on readers' accuracy in interpreting computed tomographic (CT) colonographic images. The contributing institutions performed the examinations under approval of their local institutional review board, with waiver of informed consent, for this HIPAA-compliant study. A cohort of 100 colonoscopy-proved ...
Chu Hsin - - 2011
To assess the ability of mean platelet volume (MPV) to detect acute coronary syndromes (ACS) in Chinese patients within 4 h of chest pain onset. Consecutive adult Chinese patients who arrived at an emergency department (ED) with acute chest pain (onset within 4 h) between May and August 2009 were recruited. The ...
Nishigaki Kazuhiko - - 2010
Although calcium channel blockers (CCB) are highly effective for suppression of vasospastic angina (VSA) attacks, their prognostic effects in VSA patients remain to be examined in a large number of patients. Databases for related papers were searched and then a meta-analysis regarding the effects of CCB on major adverse cardiovascular ...
Kontos Michael C - - 2010
OBJECTIVES: The aim of this study was to assess the performance of beta-methyl-p-[123I]-iodophenyl-pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) to detect acute coronary syndromes (ACS) in emergency department patients with chest pain. BACKGROUND: Emergency department diagnosis of chest pain is problematic, often requiring prolonged observation and stress testing. BMIPP ...
Carryer Damita Jo - - 2010
The purpose of this study was to determine the prevalence and timing of routine follow-up single-photon emission computed tomography (SPECT) studies after a normal stress SPECT scan compared with the patient's warranty period (ie, time to 1% risk of death or myocardial infarction). We identified patients at Mayo Clinic Rochester ...
Tamura Akira - - 2010
Previous studies have shown a higher prevalence of obstructive sleep apnea (OSA) in patients with coronary artery disease than in control subjects. However, the association between coronary spastic angina pectoris (CSA) and OSA has not been investigated. Accordingly, we examined this association. We performed overnight polysomnography in 42 consecutive patients ...
Arao Kenshiro - - 2010
This study explored the clinical significance of CD34(+)/133(+) circulating progenitor cell (CPC) counts in patients with stable angina pectoris (AP) who underwent percutaneous coronary intervention (PCI). Subjects comprised 52 patients with stable AP requiring PCI and 50 control patients without AP. In the AP group, blood samples were taken before ...
Van Werkhoven Jacob M - - 2010
PURPOSE: To evaluate the prognostic value of multidetector computed tomographic (CT) coronary angiography in a diabetic population known to have or suspected of having coronary artery disease (CAD) compared with that in nondiabetic individuals. MATERIALS AND METHODS: Institutional review board approval and patient informed consent were obtained. Three hundred thirteen ...
Bruschi Giuseppe - - 2010
INTRODUCTION: Atherosclerotic vascular disease is the leading cause of morbidity and mortality in patients with end-stage renal disease. Several authors reported that chronic dialytic patients have a high operative risk when submitted to coronary artery bypass grafting (CABG) on cardiopulmonary bypass (CPB) whereas little information exists about off-pump myocardial revascularization ...
Prinz Christian - - 2010
Sleep-disordered breathing (SDB) has a prognostic impact in patients with cardiac diseases. We included 257 patients with preserved left ventricular function and angiographically proven coronary artery disease (CAD). All patients underwent cardiorespiratory polygraphy. In 251 patients high-sensitive C-reactive protein and fibrinogen were measured. SDB was documented in 188 patients (apnea-hypopnea-index ...
Duran Mustafa - - 2010
Microalbuminuria is associated with atherosclerosis and it is a strong and independent predictor of increased risk for cardiovascular morbidity and mortality. However, the underlying mechanisms of the association of albuminuria and cardiovascular disease are not well understood. We examined the association of endothelial dysfunction with microalbuminuria in non-diabetic and non-hypertensive ...
Shakya D R - - 2010
Self-injurious behavior (SIB) or self-mutilating behavior (SMB) is rare but can occur in temporal lobe epilepsy. Such a behavior during seizures is not usually recalled by patient. Here is a case with self mutilating behavior in left temporal lobe epilepsy, presented because of its rare manifestation and diagnostic dilemma. A ...
Imanishi Toshio - - 2010
We examined whether distinct monocyte subsets relate in specific ways to coronary fibrous cap thickness (FCT) in patients with unstable angina pectoris (UAP). Forty patients with UAP who underwent percutaneous coronary intervention were enrolled in this study. The changes in the non-culprit FCT were assessed by optical coherence tomography (OCT) ...
Chang Shih-Tai - - 2010
Introduction.  Accumulated evidence shows that erectile dysfunction (ED) may be a precursor of coronary artery disease (CAD). Aims.  The purpose of this study was to explore the differences in coronary phenotypes between patients with ED and patients with angina pectoris. Methods.  The study enrolled 30 ED patients (study group) and ...
Kitabata Hironori - - 2010
Increased neovascularization in atherosclerotic plaques is associated with plaque vulnerability. The high resolution of optical coherence tomography (OCT) might provide a chance to directly visualize plaque neovascularization in vivo. The aim of the present study was to investigate the relation between microchannels in culprit plaques identified by OCT and plaque ...
Medeiros Ana Maria Brito - - 2010
The oxidation of low-density lipoprotein (oxLDL) induces the formation of immunogenic epitopes in molecules. The presence of autoantibodies against oxLDL has been demonstrated in the serum of patients with coronary artery disease (CAD). However, the role of these autoantibodies in the pathophysiology of acute coronary syndromes (ACS) and their clinical ...
Wu Yunfei - - 2010
Elevation of homocysteine and thioredoxin (Trx) levels was found in some patients with coronary artery diseases (CAD). However, their correlations with CAD were not clear. Dysfunction of thioredoxin/thioredoxin reductase (TrxR) may cause oxidative stress that is common to CAD. We seek to determine the association among homocysteine, Trx/TrxR and CAD. ...
Zhu Cheng-gang - - 2010
Spontaneous attack of variant angina (VA) is a unique component of coronary artery disease (CAD), and associated with severe cardiac events. However, no data are available regarding sex differences in Chinese patients with spontaneous attacks of VA. Accordingly, the present retrospective study was initiated to evaluate the Clinical characteristics of ...
Gillebert Carl - - 2010
BACKGROUND: More and more children, who suffered from Kawasaki disease in childhood, reach today adulthood. The future perspectives of these patients are not yet well defined, therefore, we wanted to determine mid-term outcome of our Kawasaki patients. METHODOLOGY: All patients with the diagnosis of Kawasaki disease were selected from the ...
Minha Sa'ar - - 2010
INTRODUCTION: The incidence of normal or near-normal coronary angiography (NONCA) in patients undergoing coronary angiography, who have in patients with acute coronary syndrome (ACS) is reported between 1 and 12%. Earlier studies reported conflicting results regarding the nature and outcome of these patients. We used Acute Coronary Syndrome Israeli Survey ...
Sinan Deveci O - - 2010
This study was designed to determine the relationship between serum uric acid level and the presence and severity of coronary artery disease (CAD). A total of 1012 patients who underwent coronary angiography were included in this study. All patients were assessed for the presence of cardiovascular risk factors and ongoing ...
Cannavò S - - 2011
Assessment of coronary calcium deposits (CCD) by coronary computed tomography (CT) was recently introduced for evaluation of risk to develop events related to coronary heart disease (CHD). We investigated occurrence of CCD in 19 hypopituitary patients (patients), 34 healthy (H) subjects (H controls) and 36 patients with a similar rate ...
Kwon Hyukchan - - 2010
Accurate identification of patients with acute coronary syndrome (ACS) is often difficult especially when an electrocardiogram (ECG) does not show typical elevation of ST segment. The aim of the present study was therefore to evaluate the efficacy of magnetocardiography (MCG) for diagnosis of ACS in patients with acute chest pain ...
Kuznetsov Vadim A - - 2010
OBJECTIVE: To compare the prevalence of cardiovascular risk factors and clinical manifestations of coronary artery disease (CAD) between patients with type 2 diabetes mellitus (DM) and CAD who lived at northern latitudes vs. those who resided at southern latitudes in the Tyumen region, western Siberia. STUDY DESIGN: This retrospective study ...
Ishikawa Yuichi - - 2010
The JELIS trial examined the preventive effects of eicosapentaenoic acid (EPA) on coronary artery disease (CAD) in hypercholesterolemia. Previous investigators have reported that patients with peripheral artery disease (PAD) have a poor prognosis due to the potential risk for CAD. We conducted a subanalysis to examine whether the incidence of ...
Andréll P - - 2010
OBJECTIVE: To assess the long-term effect of spinal cord stimulation (SCS) on angina symptoms and quality of life in patients with refractory angina pectoris defined as severe angina due to coronary artery disease resistant to conventional pharmacological therapy and/or revascularisation. METHODS: During 2003-2005, all patients with refractory angina referred for ...
Kashiwagi Manabu - - 2010
The aim of the present study was to examine the relation between monocyte subsets and the presence, extent, and vulnerability characteristics of non-calcified coronary plaques (NCPs) as assessed by multidetector computed tomography (MDCT). We studied 73 patients with stable angina pectoris who underwent MDCT. Two monocyte subsets (CD14(+)CD16(-) and CD14(+)CD16(+)) ...
Roman Raquel Melchior - - 2010
BACKGROUND: Atherosclerosis is a chronic inflammatory process, and myeloperoxidase (MPO) seems to contribute directly to the pathogenesis of acute coronary syndrome (ACS). OBJECTIVE: To compare MPO levels among the patients with stable and unstable ischemic heart disease and to evaluate their independent prognostic value for cardiovascular events. METHODS: MPO and ...
Greco Thomas P - - 2010
Oxidized low-density lipoprotein (oxLDL)/beta(2)-glycoprotein I (beta2GPI) complexes have been implicated in atherogenesis. oxLDL/beta2GPI complexes were measured in 339 patients with suspected acute coronary syndromes. Approximately 68% had angiographically documented coronary artery disease (CAD) and significantly higher mean + or - SD levels of oxLDL/beta2GPI (3.75 + or - 6.31 U/mL) ...
Lin Chia-pin - - 2010
No reflow phenomenon during percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) has an unfavorable outcome. Previously, some investigators have tried to determine the predictors of this phenomenon, but there are still controversies as to whether it is possible to make predictions beforehand. Here we report the first clinical ...
Alisir Sabahat S Goztepe Training and Research Hospital; and Department of Internal Medicine, Istanbul School of Medicine, Istanbul, - - 2010
Endothelial dysfunction (ED) has been reported in patients with autosomal-dominant polycystic kidney disease (ADPKD). Coronary flow velocity reserve (CFVR) is a noninvasive test showing endothelial function of epicardial coronary arteries and coronary microcirculatory function. The aim of this study was to investigate the effect of the angiotensin receptor blocker, telmisartan, ...
Williams Benjamin B Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota 55407, - - 2010
To determine the contemporary prevalence of and mortality in patients with coronary artery disease (CAD) not amenable to revascularization. A growing number of patients have severe CAD with ongoing angina despite optimal medical therapy which is not amenable to traditional revascularization. Limited data exist on contemporary prevalence and outcome for ...
Jha Hem C - - 2010
Inflammatory processes play a role in the pathogenesis of atherosclerosis, and plasma circulatory markers have been associated with cardiovascular risk. There is no single report in which adhesion molecule and circulatory cytokines have been evaluated in a single population set with coronary artery disease (CAD) on the basis of gender. ...
Cotton J M - - 2010
INTRODUCTION: There is considerable interindividual variation in response to the antiplatelet agent clopidogrel. Hyporesponse predicts negative outcomes in patients presenting with a variety of ischemic cardiac conditions and following intracoronary stent placement. Many tests of clopidogrel activity are time consuming and complex. Short thromboelastography (s-TEG) allows rapid measurement of platelet ...
Losi Maria-Angela - - 2010
Aortic valve sclerosis (AVS) is a marker of cardiovascular risk; its prevalence increases in elderly and in patients with hypertension and/or coronary arterial disease (CAD). There are no data available in patients with peripheral arterial disease (PAD) and with both CAD and PAD. To investigate the presence of AVS, 57 ...
Di Sciascio Germano - - 2010
To evaluate safety and effectiveness of clopidogrel reloading in patients on chronic clopidogrel therapy undergoing percutaneous coronary intervention (PCI). Five hundred and three patients on >10 days clopidogrel therapy (41% with non-ST-segment elevation acute coronary syndrome, ACS) randomly received 600 mg clopidogrel loading 4-8 h before PCI (n = 252) ...
Fukui Toshihiro - - 2010
The aim of the present study was to compare the early outcomes of patients undergoing off-pump coronary artery bypass grafting (OPCAB) with and without previous percutaneous coronary intervention (PCI). We retrospectively reviewed the records of 545 patients who underwent first-time isolated OPCAB from September 2004 to June 2007. Overall, 154 ...
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