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Holm C - - 2000
Resuscitation from shock based on invasive hemodynamic monitoring has been widely used in trauma and surgical patients, but has been only sparsely evaluated in thermally injured patients, probably due to fear of invasive monitoring in this group of patients. However, end-point resuscitation to fixed circulatory and oxygen transport values has ...
Brun-Buisson C - - 2000
OBJECTIVE: To examine the incidence, risk factors, aetiologies and outcome of the various forms of the septic syndromes (the systemic inflammatory response syndrome [SIRS] sepsis, severe sepsis, and septic shock) and their relationships with infection. DESIGN: Review of published cohort studies examining the epidemiology of the septic syndromes, with emphasis ...
de Sèze M - - 2000
Critical illness polyneuropathy (CIP) is a reported cause of varying degrees of neuromuscular weakness in patients with multiple organ failure. Little is known concerning predictive factors of neurological recovery. The critical care conditions, neurological explorations and 2-year clinical follow-up of 19 patients who suffered from severe forms (quadriplegia or quadriparesis) ...
Hjorth V - - 2000
Plasmapheresis is one of the methods which has been tried in the effort to influence the course of severe sepsis with septic shock and to improve survival rates. This is a retrospective study of 17 consecutive patients with septic shock who were treated with acute plasmapheresis. Nine out of 16 ...
Bang R L - - 2000
The study group is comprised of 234 patients (6.4%) who died out of 3680 patients treated for burn injuries during the period January 1982 to December 1997 in Kuwait. There were 112 (47.9%) males and 122 (52.1%) females and their mean age was 30 years (range 1-93) when compared with ...
Yamada Y - - 1999
In this study, we investigated multiple organ dysfunction syndrome (MODS) and nuclear matrix protein (NMP), which is an indicator for apoptosis, in burn patients. The subjects were 17 patients with a total burn surface area (TBSA) of 26% or more. Eight of them had MODS, and nine did not. Seven ...
Tortorolo L - - 1999
This report describes surfactant treatment in a burned infant with severe respiratory failure. In this patient the instillation of surfactant rapidly improved compliance, oxygen index (OI), and alveolar-capillary oxygen gradient (AaDO2), while the need for oxygen supplementation and peak positive pressure drastically decreased. The treatment was repeated after 12 hours. ...
Chen Y S - - 1999
BACKGROUND: Acute myocarditis (AM) complicated with refractory cardiogenic shock carries a very high mortality. We report our experience in treating these patients, who were rescued by extracorporeal membrane oxygenation (ECMO) and intravenous immunoglobulin. METHODS: Over a 5-year period, 5 patients with AM were rescued with ECMO in our hospital. Femoral ...
Webster N R - - 1999
It has long been recognised that the physiological response of the patient to a stress or disease process will very largely determine the outcome. It is important, therefore, to monitor the physiological responses of patients since this not only allows the assessment of physiological reserve but will also give a ...
Sloan E P EP Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA. - - 1999
Severe, uncompensated, traumatic hemorrhagic shock causes significant morbidity and mortality, but resuscitation with an oxygen-carrying fluid might improve patient outcomes. To determine if the infusion of up to 1000 mL of diaspirin cross-linked hemoglobin (DCLHb) during the initial hospital resuscitation could reduce 28-day mortality in traumatic hemorrhagic shock patients. Multicenter, ...
Cook C H - - 1999
BACKGROUND: Rates of discharge of surgical ICU (SICU) patients to extended care facilities (ECF) increase as SICU length of stay (LOS) increases. Increased SICU LOS and APACHE II scores have been related to increased hospital mortality. This study evaluated factors influencing ECF survival after SICU patient discharge. STUDY DESIGN: We ...
Edbrooke D L - - 1999
OBJECTIVE: To determine the patient-related costs of care for critically ill patients with severe sepsis or early septic shock. DESIGN: Retrospective, longitudinal, observational study during a 10-month period. SETTING: Adult general intensive care unit (ICU) in a university hospital located in the United Kingdom. PATIENTS: The study population consisted of ...
Turner A - - 1999
OBJECTIVE: To determine the presence of otherwise undetected myocardial cell injury in patients with septic shock using daily measurements of cardiac troponin I (cTN I). DESIGN: Prospective observational study. SETTING: Intensive care unit of a tertiary institution. PATIENTS: Fifteen consecutive patients with septic shock and six mechanically ventilated patients without ...
Yu B H - - 1999
This article reviews the literature about the extent of posttraumatic stress disorder (PTSD) in patients with burns. PTSD is a relatively new diagnostic label, although the emotional effects of severe trauma have long been recognized. A burn injury-one of the most traumatic of all injuries--can be accompanied by serious psychological ...
Zak A L - - 1999
Respiratory failure that requires endotracheal intubation is an uncommon but potentially fatal complication of scald burns in children. Because scalds are rarely associated with a direct pulmonary injury, the pathophysiology of respiratory failure is unclear. A possible mechanism may be upper airway edema, diminished pulmonary compliance secondary to fluid resuscitation, ...
Pilling J - - 1999
BACKGROUND: The benefits of long-term oxygen supplementation in COPD patients with hypoxemia are well established. The standard approach to prescribing oxygen uses a static assessment of oxygen requirements in a hospital or clinic setting. The assumption behind this approach is that patients will maintain a "therapeutic" hemoglobin oxygen saturation (SpO2) ...
Tang G J - - 1999
BACKGROUND: This prospective, comparative study was designed to estimate the volume of distribution (Vd) and elimination rate constant (K(e)) of gentamicin and to determine the clinical factors affecting the pharmacokinetics of gentamicin in different stages of sepsis. METHOD: Seventy-seven critically ill patients treated with gentamicin for gram-negative sepsis were included. ...
García-Sánchez V - - 1999
From January 1993 to December 1997, 179 patients with electrical injuries were admitted to our burn unit. There were 55 patients with high-tension injuries and 124 patients with low-tension injuries. A high incidence of amputation (42%) is one of the characteristic sequelae of high-tension injuries, but no patients in this ...
Ringbaek T - - 1999
The aim of the study was to investigate compliance with long-term oxygen therapy (LTOT), the consumption of mobile oxygen and factors that might influence on these measures. The study included 182 patients with LTOT and 125 patients answered a questionnaire on daily activities. Information on arterial gas tension, lung function, ...
Rheineck-Leyssius A T - - 1999
STUDY OBJECTIVE: To determine the effect of a new pulse oximeter (Nellcor Symphony N-3000, Pleasanton, CA) with signal processing technique (Oxismart) on the incidence of false alarms in the postanesthesia care unit (PACU). DESIGN: Prospective study. SETTING: Nonuniversity hospital. PATIENTS: 603 consecutive ASA physical status I, II, and III patients ...
Holm C - - 1999
Acute renal failure (ARF) is a well known complication of severe burns and is an important factor leading to an increase in mortality. In order to analyze possible pathogenetic and prognostic factors associated with ARF in burned patients we reviewed in a retrospective study the files of 328 patients with ...
Sun D - - 1999
Based on the concept of the systemic inflammatory response syndrome (SIRS), a one-year retrospective study was carried out among a total of 2389 patients transported to the emergency room by ambulance. With respect to 351 patients who had all data necessary for evaluating SIRS criteria in 369 hospitalized patients, 200 ...
Hadjiiski O G - - 1999
Effective local treatment is very important in preventing wound infection and its generalization and ensuring successful skin grafting. The aim of our study is to compare the activity of four topical agents [deflamol (20 patients), polyvidone-iodine (21 patients), flammazine (silver sulphadiazine--SSD) (28 patients) and flammacerium (SSD with cerium nitrate) (five ...
Chang P - - 1999
We undertook a retrospective study of the risk factors determining outcome of nontraumatic patients with shock in the pediatric emergency service. From October 1992 through September 1997, 22 patients with the diagnosis of shock were identified, including 11 with septic shock (50%), 7 with hypovolemic shock (32%) and 4 with ...
Fleming RM - - 1999
Determination of the severity of coronary artery disease (CAD) by single photon emission computed tomography (SPECT) imaging has previously been shown to have greater sensitivity, specificity, and accuracy when performed with pharmacologic stress using dobutamine than by standard dose dipyridamole (SDD) or exercise stress testing (EST) prior to SPECT imaging. ...
Hasdai D - - 1999
AIMS: Reteplase has been reported to achieve better patency of the infarct artery than alteplase. As infarct artery patency is strongly associated with survival among patients with cardiogenic shock, we postulated that treatment with reteplase would improve outcomes among shock patients. METHODS: We compared 30-day mortality rates among patients in ...
Javid G - - 1999
BACKGROUND: Although upper gastrointestinal endoscopy is generally a safe procedure, it is known to be associated with arterial oxygen desaturation, resulting in rare serious cardio-pulmonary events. OBJECTIVE: To determine the severity of oxygen desaturation during nonsedated upper gastrointestinal endoscopy and study the effect of various variables on oxygen saturation. METHODS: ...
Bernardin G - - 1998
OBJECTIVES: a) To investigate the functional consequences of sepsis on the beta-adrenergic signal transduction in human circulating lymphocytes; b) to appreciate sepsis-associated catecholamine and cytokine release. DESIGN: Experimental, comparative study. SETTING: Research laboratory in a university hospital. SUBJECTS: Healthy controls (n = 10); critically ill patients who were not septic ...
Andresen M - - 1998
PURPOSE: The purpose of this study was to assess the acute effects of methylene blue, an inhibitor of nitric oxide synthesis, on hemodynamics and gas exchange in patients with refractory septic shock in a prospective clinical trial at medical and surgical intensive care units in a tertiary university hospital. PATIENTS ...
Dai N T - - 1998
Over the last half century, advances in treatment have changed the principal cause of death in burn patients from burn shock and wound sepsis to pulmonary sepsis, of which inhalation injury has always played a key role in morbidity and mortality. Even though Navar et al., Am. J. Surg. 1985;150:716-720 ...
Muehlberger T - - 1998
Home oxygen therapy has been used to provide symptomatic relief of breathlessness for more than 20 yr. Continuous low-flow oxygen can improve exercise tolerance and decrease pulmonary hypertension in patients suffering from chronic obstructive airway disease. The majority of these patients have been long-time smokers. Despite routine warnings about potential ...
Godwin Y - - 1998
There are few studies which address the burnt male patient who has been intentionally assaulted by his partner. Thirty such patients were admitted to the Somerset Hospital Burns Unit between January 1993 and May 1995. The average age was 37 years and the mean total burn surface area was 19.6% ...
Magboul M M MM King Khalid University Hospital, Riyadh, K.S.A. - - 1998
Based on the observation that the degree of wakefullness measured by Post Anesthetic Recovery (PAR) score in some patients does not correlate with their oxygen saturation, the authors decided to carry on a study to validate that assumption. Three hundred patient ASA I & II were studied. Oxygen saturation and ...
Forceville X - - 1998
OBJECTIVES: To confirm early, marked decrease in plasma selenium concentrations in patients admitted to a surgical and medical intensive care unit (ICU), and to study this decrease according to the presence or absence of systemic inflammatory response syndrome (SIRS), sepsis, or direct ischemia-reperfusion. DESIGN: Prospective, observational study. SETTINGS: Collaboration between ...
Kariya N - - 1998
Clonidine has both analgesic and sedative actions, and it has been used in a variety of settings as a sedative, or both. We administered oral clonidine with intravenous ketamine to a burn patient to control severe pain. Clonidine produced good analgesia and sedation. In addition, clonidine counterbalanced the sympathetic stimulation ...
De-Souza D A - - 1998
This retrospective analysis of burn patients in a University Hospital in the state of São Paulo, Brazil, was carried out to characterize this population and to identify the factors that affect the mortality rate. All patients hospitalized from January 1990 to April 1995 (n = 229, 3.6 patients/month) and who ...
- - 1998
To quantify effect on mortality of administering human albumin or plasma protein fraction during management of critically ill patients. Systematic review of randomised controlled trials comparing administration of albumin or plasma protein fraction with no administration or with administration of crystalloid solution in critically ill patients with hypovolaemia, burns, or ...
Jones G R - - 1998
Standard definitions of sepsis have been proposed and have been widely adopted. Recognition of the systemic inflammatory response syndrome (SIRS) and assessment of its severity can easily be achieved at the bedside using basic observations and simple laboratory tests. Fulfillment of standardized criteria defining increasing severity of sepsis or manifestation ...
Ohashi K - - 1998
BACKGROUND: It has been reported that large amounts of nitric oxide (NO) are released in patients with sepsis. NO is converted to methemoglobin and nitrate. This study was designed to determine whether blood methemoglobin levels were increased in patients with sepsis or septic shock. METHODS: Forty-five critically ill patients including ...
do Rosário Caneira da Silva M - - 1998
Nitric oxide (NO) is an important mediator in numerous physiological and pathophysiological events. After thermal injury an increase in plasma and urinary levels has been observed. The real importance of this fact is unknown. The stable NO derivatives (NO2-/NO3-) plasma concentrations were determined in 27 burned patients admitted to the ...
Pallua N - - 1998
Damage to the respiratory tract caused by inhalation of toxic products of combustion with subsequent development of an acute respiratory distress syndrome (ARDS) is one of the main causes of death in burn patients. Treatment with an exogenous surfactant is a therapeutic option for which there has previously been no ...
Janezic T F - - 1998
Two elderly patients with 6 and 4 per cent total body surface area (TBSA) full thickness burns were entirely skin grafted solely under topical anaesthesia with EMLA cream. Both patients had several concurrent illnesses. The risk of general or regional anaesthesia for their general condition was much greater than the ...
Iwama H - - 1998
A 67-yr-old patient with septic shock caused by gram-positive infection fell into circulatory collapse. Direct hemoperfusion with an endotoxin-removing column was then carried out for 120 min. As a result, blood pressure and systemic vascular resistance increased significantly during this therapy. Cardiac output changed from hyperdynamic to normodynamic, and plasma ...
Le Bourdellès G - - 1998
STUDY OBJECTIVES: To assess the impact of pulse oximetry (SpO2) on the indications and the number of arterial blood gas (ABG) levels ordered in an adult emergency department (ED). DESIGN: A prospective study during a 2-month period in 1993 with a pulse oximeter available and a comparison with the same ...
Hayes M A - - 1998
Perioperative haemodynamic optimization of high-risk surgical patients seems to be associated with a reduction in morbidity and mortality. There is, however, no evidence to support the use of treatment directed at achieving survivor values of oxygen delivery and consumption in critically ill patients after admission to intensive care. Mitochondrial dysfunction ...
Bojić I - - 1998
Inappropriate body response is, besides the infectious agent, responsible for the genesis of sepsis and septic shock. It is non-specific and in cascade of events it can hardly be controlled. The results of immunoglobulins administration compared to the disease course and outcome have been compared and analyzed in 135 patients ...
Brown A F - - 1998
Tick bite anaphylaxis has rarely been reported. It may follow the bite of any of the different tick life cycle forms, is related to the release of salivary juices, and may range from mild itch to severe wheeze or shock. Data obtained suggest that it is more common and potentially ...
Still J M - - 1998
A retrospective review of all 443 burn patients admitted during a 13-month period from October 1, 1992 to October 31, 1993, was completed. Of these, 8 were transferred and eliminated from the study. Twenty-two patients who were felt to be terminal on admission and did not have blood cultures were ...
Webb J G - - 1998
Management of the patient with cardiogenic shock requires rapid confirmation of the diagnosis and exclusion of potentially correctable conditions. Early echocardiography is helpful to exclude mechanical causes of shock, such as unsuspected severe mitral insufficiency. Thrombolytic therapy may help prevent shock, but its role in established shock is not clear. ...
Goris R J - - 1998
The systemic inflammatory response syndrome (SIRS) and acute reflex sympathetic dystrophy syndrome (RSD) share clinical signs of severe inflammation, a protracted course, and a similar problem of impaired oxygen utilization. The difference is that SIRS patients have these signs and symptoms systemically and are severely ill in the intensive care ...
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