Search Results
Results 351 - 400 of 1435
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Farmakis Dimitrios - - 2009
Hyponatremia is the most common electrolyte abnormality found in hospitalized patients with heart failure. It may occur in patients who have hypovolemic, hypervolemic, or euvolemic state. It is usually not corrected by available therapies. It is a major predictor of prognosis, and correction of hyponatremia can be effectively accomplished by ...
Negrão Carlos E - - 2009
BACKGROUND: The progression of heart failure in Chagas' disease has been explained by remodeling, leading to neurohumoral activation, or by the direct parasite damage to parasympathetic neurons during acute phase, leading to early sympathetic activation and progressive heart failure. To help distinguish between these hypotheses we studied muscle sympathetic nerve ...
Anand Inder S - - 2008
Anemia is a common comorbidity in patients with heart failure and is associated with worse long-term outcomes. Although the cause of anemia in heart failure is unclear, the weight of evidence suggests that renal dysfunction, along with neurohormonal and proinflammatory cytokine activation in heart failure, favors the development of anemia ...
Ishibashi Yutaka - - 2008
BACKGROUND: Activation of inducible nitric oxide synthase (iNOS) has been reported in congestive heart failure (CHF) conditions. However, it is unknown whether activation of iNOS affects prognosis of CHF patients. We prospectively studied the influence of activation of iNOS in the forearm on the outcome of CHF patients. METHODS AND ...
Castillo J G - - 2008
BACKGROUND: The management of patients with carcinoid heart disease poses two major challenges for the anaesthetist: carcinoid crisis and low cardiac output secondary to right ventricular (RV) failure. Carcinoid crises may be precipitated by the administration of catecholamines and histamine-releasing drugs. METHODS: We analysed a series of 11 patients [six ...
Jögi Jonas - - 2008
OBJECTIVE: Left heart failure (LHF) is a common and frequently overlooked condition owing to insufficient diagnostic methods. This can potentially delay onset of treatment. Our clinical experience with ventilation/perfusion single photon emission computed tomography (V/P SPECT) indicates that perfusion shows an antigravitational distribution pattern in LHF. The aim of the ...
Ruygrok Peter N - - 2008
PURPOSE: The purpose of this study is to describe the first experience of implanting a new left ventricular assist device in pediatric patients with end-stage heart failure. DESCRIPTION: In two recent prospective, international, multicenter clinical trials, three children (aged </= 16 years) were implanted successfully with the VentrAssist (Ventracor Limited, ...
Oldenburg Olaf - - 2008
Sleep disordered breathing (SDB) has a high prevalence and prognostic impact in patients with chronic heart failure (CHF). Aim of this study was to investigate variability of SDB parameters in patients with stable CHF. Cardiorespiratory polygraphy was used to determine SDB in two consecutive nights in 50 CHF patients (NYHA ...
Sadanaga Tsuneaki - - 2009
The incidence of enalapril-induced cough was evaluated in 199 patients with congestive heart failure. Cough was more frequent in class I or II patients (28%) than in class III (4.1%, p<0.01) and class IV (0%, p<0.01) patients. Brain natriuretic peptide level was lower in patients in the cough (+) group ...
Santoro Giovanni M - - 2008
Scanty data exist about the relation between acute heart failure (HF) and acute myocardial infarction (AMI). To assess the impact of HF on outcome in AMI patients treated with primary percutaneous coronary intervention (PCI). Out of 2,089 AMI patients, 82% did not present HF, 17% presented HF on admission and ...
Ishizawa Tetsuro - - 2008
OBJECTIVE: Anorexia nervosa (AN) is considered to have a significant risk for sudden death because of cardiac complications, and abnormalities of the autonomic nervous system might be a cause of cardiac dysfunction. The aim of this study was to investigate autonomic nervous system function in AN patients by analyzing heart ...
Norgard Nicholas B - - 2008
Angiotensin-converting enzyme (ACE) inhibitors and beta-blockers make up the cornerstone of therapy for patients with heart failure involving left ventricular dysfunction. These drug classes have been proven to decrease morbidity and mortality in patients with heart failure. Unfortunately, many patients remain symptomatic and experience disease progression despite taking both an ...
Howlett Jonathan G - - 2008
Acute decompensated heart failure (ADHF) is a common syndrome that precedes over 100,000 hospitalizations in Canada per year (with length of stay in excess of six to eight days), making this the most costly disorder for patients older than 65 years of age. Over 85% of ADHF patients present with ...
Bobay Kathleen L - - 2008
This study explored patient-level factors associated with failure to rescue (FTR). The overall incidence of FTR in 5 Midwestern hospitals was 0.03%, which is much lower than reported in other studies. Five key patient parameters were found to be statistically significant, but subtle, indicators of impending FTR. These were changes ...
de Denus Simon - - 2008
The benefits of angiotensin II receptor blockers (ARBs) in patients with heart failure who are treated with standard pharmacotherapy, including an angiotensin-converting enzyme (ACE) inhibitor, were demonstrated in 2 large randomized trials. It is currently impossible to determine which patient will benefit from the addition of an ARB. To explore ...
Maak Carley Ann - - 2011
In patients with dyspnea, prehospital and emergency providers make therapeutic decisions before a diagnosis is established. Inhaled beta-2 agonists are frontline treatment for patients with dyspnea due to asthma or chronic obstructive pulmonary disease (COPD) exacerbations. However, these agents have been associated with increased adverse events when administered chronically to ...
van Dijk Nynke - - 2008
Patients with Marfan syndrome have a tall stature, which could be associated with low orthostatic tolerance. Fatigue, a common complaint of these patients, is also related to orthostatic intolerance. Treatment with beta-blockers, to prevent aortic complications, could be a reinforcing factor of both. This study aimed to investigate (1) the ...
Laederach-Hofmann Kurt - - 2008
AIM: We conducted a study to investigate whether patients with somatization disorders (ICD-10, F45.0) show abnormal values in autonomic testing. METHOD: 35 patients with a diagnosis of somatization disorder (SP) were matched to 35 healthy volunteers (HV). International standardized autonomic testing based on heart rate variation and continuously measured blood ...
Hare Joshua M - - 2008
OBJECTIVES: This study evaluated whether a xanthine oxidase (XO) inhibitor, oxypurinol, produces clinical benefits in patients with New York Heart Association functional class III to IV heart failure due to systolic dysfunction receiving optimal medical therapy. BACKGROUND: Increased XO activity may contribute to heart failure pathophysiology. METHODS: Patients (n = ...
Kardelen Firat - - 2008
Cardiac dysfunction, including congestive heart failure and fatal arrhythmia, is a frequent cause of death among children with thalassemia major (TM). Autonomic nervous system activity typically is measured by a series of cardiovascular autonomic function tests, but these tests are unsuitable for young patients because they are invasive or complex. ...
Wang Norman C NC Northwestern University Feinberg School of Medicine, Chicago, IL 60611, - - 2008
Hospitalization for heart failure is associated with high postdischarge mortality and morbidity. The predictive value of the QRS duration during admission for heart failure has not been well studied. To investigate the predictive value of the QRS duration in patients hospitalized for heart failure with reduced left ventricular ejection fraction ...
Düngen Hans-Dirk - - 2008
Chronic heart failure (CHF) is a widespread disease with severe quality of life impairment and a poor prognosis. Beta-blockers are the mainstay of CHF therapy; yet they are under-prescribed and under-dosed in clinical practice. This is particularly evident in elderly patients, which may be due to a fear of side-effects ...
Shirley Shelby - - 2008
PURPOSE: The purpose of this review was to summarize the literature on the relationship between obesity and survival in persons with heart failure (HF). In particular, the article examines the ways in which studies define body size/composition (body mass index [BMI], body composition, weight, cachexia, fluid retention, or albumin) and ...
Valle Hector Alonso - - 2008
BACKGROUND: Early identification of acute coronary syndrome (ACS) in the emergency room is still a difficult task. The objective of this study is to estimate the reliability of heart-type fatty acid binding protein (H-FABP) in identifying ACS in the early stage of chest pain onset. METHODS: In a prospective multicentre ...
Diercks Deborah B - - 2008
The goal of the Society of Chest Pain Centers Heart Failure Discharge Recommendations Committee was to review the available literature and currently published guidelines to provide recommendations for acute heart failure providers regarding observation unit discharge criteria. Explicit and validated criteria for discharging patients from the emergency department or observation ...
Six A J - - 2008
Chest pain is one of the most common causes of presentation to the emergency room. The diagnosis of non-ST-elevation acute coronary syndrome typically causes uncertainty. Classical considerations for risk stratification are History, ECG, Age, Risk factors and Troponin (HEART). Each can be scored with zero, one or two points, depending ...
Garcia-Touchard Arturo A Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, - - 2008
Congestive heart failure (HF), an exceedingly common and costly disease, is frequently seen in association with central sleep apnea (CSA), which often manifests as a periodic breathing rhythm referred to as Cheyne-Stokes respiration. CSA has historically been considered to be a marker of heart disease, since improvement in cardiac status ...
Jaski Brian E - - 2008
BACKGROUND: Ultrafiltration (UF) can rapidly and predictably remove extracellular and intravascular fluid volume. To date, assessment of UF in patients with cardiovascular disease has been confined to short- and medium-term studies in patients with a principal diagnosis of acute heart failure. METHODS: In-hospital and long-term outcomes were reviewed from consecutive ...
Celik Turgay - - 2009
High CRP levels are associated with adverse outcomes in cardiovascular diseases. hsCRP levels increase with the severity of CHF in patients with diastolic HF as well as in systolic HF. This supports a potential role for CRP in immune activation not only in systolic but also in diastolic HF. The ...
Clark Andrew L - - 2008
Approximately one third of patients with chronic heart failure have left bundle branch block (LBBB) on their 12-lead ECG. 1418 consecutive patients (average (SD) age 70.5 (10.4) years; 74% male) first seen in a community heart failure clinic between December 2001 and June 2006 had a 12 lead electrocardiogram (ECG). ...
Kasama Shu - - 2008
Many studies have shown that a one-time 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphic study during a stable period is useful for determining the prognosis of patients with chronic heart failure (CHF). However, the findings from this imaging modality are well known to be improved by medical treatment for heart failure. Accordingly, this study ...
Celik Turgay - - 2009
The patients with heart failure (HF) often exhibit some degree of muscle wasting restricted to the lower limbs. This loss of tissue may become more extensive in some patients, usually when their HF is more advanced, and may affect all body compartments. The underlying metabolic causes are very complex and ...
Cygankiewicz Iwona - - 2008
BACKGROUND: Abnormal heart rate turbulence (HRT) has been documented as a strong predictor of total mortality and sudden death in postinfarction patients, but data in patients with congestive heart failure (CHF) are limited. OBJECTIVE: The aim of this study was to evaluate the prognostic significance of HRT for predicting mortality ...
Pressler Susan J - - 2008
BACKGROUND: Published studies of patients with heart failure may not include details about the challenges in the recruitment process. OBJECTIVES: To describe the recruitment process during the first 18 months of a study being conducted to evaluate cognitive deficits in patients with chronic heart failure. METHODS: Details of the recruitment ...
Kataoka Hajime - - 2008
PURPOSE: The presence of age-related pulmonary crackles (rales) might interfere with a physician's clinical management of patients with suspected heart failure. We examined the characteristics of pulmonary crackles among patients with stage A cardiovascular disease (American College of Cardiology/American Heart Association heart failure staging criteria), stratiffed by decade, because little ...
Gauna Alberto A - - 2008
OBJECTIVE: To evaluate the efficacy and safety of oral transmucosal fentanyl citrate (OTFC) in terminally ill patients experiencing dyspnea. METHODS: Nonblinded, non-controlled observational study of patients admitted to the hospice/palliative care unit for dyspnea from May 2006 to March 2007. Eligible patients were older than 18 years of age with ...
Sagar Utpal N - - 2008
Excess body weight increases the risk for many disorders including cardiovascular disease and such patients have a greater risk for developing heart failure (HF). Despite evidence demonstrating the adverse effects of excess weight, the relationship between body mass index (BMI) and mortality in HF patients remains controversial. Paradoxically, several large ...
Potapov Evgenij V - - 2008
PURPOSE: The use of ventricular assist devices (VADs) in patients with chronic end-stage or acute heart failure has led to improved survival. We present our experience since 1987. SUBJECTS AND METHODS: Between July 1987 and December 2006, 1026 VADs were implanted in 970 patients. Most of them were men (81.9%). ...
Dimopoulos Konstantinos - - 2008
BACKGROUND: Renal insufficiency in patients with ischemic heart disease and acquired heart failure is associated with higher mortality and morbidity. We studied the prevalence of renal dysfunction in adult patients with congenital heart disease (ACHD) and its relation to outcome. METHODS AND RESULTS: A total of 1102 adult patients with ...
Chen Joline L T JL Renal Section, Boston University School of Medicine, Boston, MA 02118, USA. - - 2008
Heart failure (HF) is one of the leading causes of morbidity and mortality among Americans. Despite increased interest in end-of-life care, the implications of do-not-resuscitate (DNR) orders in acutely ill patients with HF remain unclear. The goals of this observational study were to describe the use of DNR orders and ...
Mullens Wilfried - - 2008
BACKGROUND: In patients with heart failure, the degree of intraventricular mechanical dyssynchrony (intra-VMD) at baseline may predict reversal of cardiac remodeling with cardiac resynchronization therapy (CRT). OBJECTIVE: The purpose of this study was to determine the prevalence and clinical significance of intra-VMD in patients admitted for advanced decompensated heart failure ...
Hammill Bradley G - - 2008
BACKGROUND: Changes in the demographics and epidemiology of patients with cardiovascular comorbidities who undergo major noncardiac surgery require an updated assessment of which patients are at greater risk of mortality or readmission. The authors evaluated short-term outcomes among patients with heart failure, coronary artery disease (CAD), or neither who underwent ...
Bushnell Brandon D - - 2008
Evaluation and management of medical comorbidities in the perioperative period can help improve surgical morbidity and mortality. Perioperative evaluation essentially is risk assessment and minimization. Patients undergoing orthopaedic treatment may benefit from temporizing measures to reduce systemic complications associated with some procedures. Patients at increased risk of cardiac ischemia should ...
Kheterpal Sachin - - 2008
OBJECTIVE: Chronic angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin receptor blocker (ARB) therapy has been reported to result in intraoperative hypotension in patients undergoing general anesthesia. This study evaluated the association between ACE-I/ARB therapy and the hemodynamics of patients undergoing noncardiac surgery using a large patient dataset. DESIGN AND SETTING: A ...
Chavey William E - - 2008
Heart failure caused by systolic dysfunction affects more than 5 million adults in the United States and is a common source of outpatient visits to primary care physicians. Mortality rates are high, yet a number of pharmacologic interventions may improve outcomes. Other interventions, including patient education, counseling, and regular self-monitoring, ...
Torabi Azam - - 2008
AIMS: Myocardial infarction (MI) is a common cause of heart failure (HF), which may develop early and persist or resolve, or develop late. The cumulative incidence, persistence, and resolution of HF after MI are poorly described. The aim of this study is to describe the natural history and prognosis of ...
Burger Andrew J - - 2009
Recent studies have suggested that body mass index (BMI) may be an independent prognostic factor in patients with chronic heart failure (HF). It is unknown whether or not BMI has the same predictive value in acute decompensated heart failure. We studied 489 patients with the previous diagnosis of HF (84% ...
Kistorp Caroline - - 2008
Biomarkers of endothelial dysfunction, such as soluble E-selectin, and von Willebrand factor (vWf) are elevated in patients with chronic heart failure (CHF). The impact of diabetes mellitus (DM) on these biomarkers, and their relation to prognosis remains unknown. to investigate the impact of DM on plasma levels and the prognostic ...
Zittermann Armin - - 2008
Vitamin D receptor knockout mice develop typical signs of congestive heart failure (CHF). In approximately 20% of stable CHF patients, frankly low concentrations of the vitamin D hormone calcitriol are found. We investigated whether serum calcitriol concentrations predict clinical outcome in end-stage CHF. We collected blood samples in 383 end-stage ...
Bakan Gülcan - - 2008
AIM: This paper is a report of a study to examine the effects of a Roy Adaptation Model-based experimental education, exercise and social support programme on adaptation in persons with heart failure. BACKGROUND: In the past 20 years, a large number of studies have evaluated heart failure. Several studies of ...
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