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Yalcin Suayib - - 2010
The role of circulating tumor cells (CTCs) in the management of colorectal cancer has not yet established. In present study, we aimed to investigate the relationship between clinicopathological characteristics and CTC levels in patients with colorectal carcinoma. The isolation of CTCs in blood was performed with the semi-automated CellSearch System ...
von Eckardstein Kajetan L - - 2010
The subset of patients suffering from meningiomas truly originating in or extending into the internal auditory canal is not well described in the literature. To evaluate postoperative facial motor and hearing outcomes in patients undergoing resection of meningiomas originating in or extending into the internal auditory canal. Chart reviews were ...
Kitajima Naoharu - - 2011
The aim of the present study was to clarify the relationship between Eustachian tube function and inner ear function, especially with respect to the hearing ability of patients with Meniere's disease. Patients with Meniere's disease underwent nystagmic examinations and audiometric measurements, including hearing tests, tympanometry, and Eustachian tube function tests ...
Iwasaki Shinichi - - 2011
Substantial numbers of patients with posterior canal benign paroxysmal positional vertigo (p-BPPV) have signs of utricular dysfunction at baseline. This improves after performing the canalith repositioning procedure. To evaluate the changes of subjective visual horizontal (SVH) in patients with p-BPPV before and after treatment with the canalith repositioning procedure. Twenty-six ...
Feigl G C - - 2011
Dizziness, a common postoperative symptom in patients with vestibular schwannomas (VSs) has a negative effect on the course of recovery, particularly in patients with severe symptoms. Reports on incidence and possible risk factors contributing to these symptoms are inconsistent and sometimes even contradictory. In order to establish a profile of ...
Worsøe Lise - - 2010
On the basis of a nationwide registration during a 5-year period (1999-2003), the frequency and severity of hearing loss was investigated retrospectively in 343 consecutive Danish patients who survived pneumococcal meningitis, to identify important risk factors (including the pneumococcal serotype) for development of hearing loss. Results of blood and cerebrospinal ...
Akay B N - - 2010
Recent clinical studies suggest that the pathogenetic mechanisms of vitiligo could be of systemic origin as vitiligo is associated with auditory abnormalities as well as other autoimmune disorders. To investigate clinical, genetic characteristics and laboratory findings of vitiligo as well as auditory abnormalities and the association of the disease with ...
Bhansali A - - 2010
Adolescent acromegaly is a rare disorder and these patients present with tall stature/gigantism, tumor mass effects and menstrual irregularities. 34 consecutive (26 males) patients having onset of disease prior to 21 years of age were included in this retrospective analysis. Their clinical features and treatment outcome were studied. Mean age ...
Yeh Shin-Joe - - 2010
Pulsatile tinnitus is a common symptom of intracranial dural arteriovenous fistulas (DAVF). This study aims to characterize the clinical and ultrasonographic features of DAVF in patients with pulsatile tinnitus. We compared the characteristics of DAVF and carotid duplex sonography (CDS) results between 67 DAVF patients with and without pulsatile tinnitus. ...
Sazgar Amir Arvin - - 2010
Our results suggest that isolated auditory or vestibular involvement is unlikely and in fact audiovestibular neuropathy can better explain auditory neuropathy. The purpose of this study was to investigate saccule and related neural pathways in auditory neuropathy patients. Three males and five females diagnosed with auditory neuropathy were included in ...
Oliveira Patrícia M - - 2010
There are few studies of language and speech in patients with Sydenham's chorea (SC). We have done an acoustic analysis of fundamental frequency (F0), duration and intensity of declarative and interrogative sentences made by 20 SC patients, 20 patients with rheumatic fever (RF) without chorea, and compared them with 20 ...
Kimani Jane W - - 2010
To examine the incidence of congenital cytomegalovirus (CMV) infection relative to common genetic etiologies of hearing loss in a pediatric population with sensorineural hearing loss (SNHL), and to characterize intracranial radiological abnormalities in patients with CMV-associated hearing loss. Retrospective study. Academic tertiary care center. A total of 112 pediatric patients ...
Thornton D - - 2011
To determine the frequency of cholesteatoma in a population of patients with chronic suppurative otitis media, and to determine whether this frequency is affected by ethnicity. The study included 6005 patients with chronic suppurative otitis media seen during the course of 30 charitable surgical 'ear camps' in Nepal. Proportion of ...
Manzari Leonardo - - 2011
The enhanced sound- and vibration-induced vestibular evoked myogenic potentials (VEMPs) and their lower threshold in patients with a thinning of the bony wall of the superior semicircular canal (superior canal dehiscence, SCD) have been interpreted as being due to the dehiscence allowing sound and vibration to activate, unusually, the receptors ...
Bassyouni Iman Hamed - - 2011
To investigate the vestibular dysfunction in a cohort of patients with systemic sclerosis (SSc) and to correlate the findings with disease parameters and microvascular involvement. Vestibular affection was assessed in 30 female SSc patients and 29 age-matched healthy females subjects by using the computerized dynamic platform posturography (CDP). Assessment of ...
Shin Byoung-Soo - - 2010
We describe a patient with Wernicke's encephalopathy who showed spontaneous upbeat nystagmus with decelerating slow phases that changed to downbeat nystagmus during upward gaze and increased during downward gaze. He also showed horizontal gaze-evoked nystagmus and impaired upward smooth pursuit. Magnetic resonance imaging demonstrated symmetric lesions involving the bilateral medial ...
Dispenza Francesco - - 2011
The aim of the study was to evaluate the true incidence, diagnosis, and treatment of benign paroxysmal positional vertigo (BPPV) arising after whiplash injury and to distinguish this type of posttraumatic vertigo from other types of dizziness complained after trauma. This was a retrospective study comprising patients referred to our ...
Ranganathan B - - 2011
To assess the diagnostic utility of using television volume as a marker for hearing loss. Prospective study using a self-administered questionnaire. ENT and audiology out-patient departments in the north of England. One hundred and seventeen patients with a history of hearing loss, undergoing pure tone audiometry for the first time. ...
Tomanovic Tatjana - - 2010
Besides spontaneous attacks of vertigo or unsteadiness, other symptoms, i.e. drop attacks, lateropulsion, illusions that the room or body is tilted, 'walking on pillows' or 'stepping into a hole', occur without precipitating head movement in almost 50% of patients with peripheral vestibular dysfunctions. The sensation of static tilt was closely ...
Desai Urmen - - 2010
Hearing loss has been described in patients with certain craniosynostotic syndromes but is poorly defined in Pfeiffer syndrome (PS). Our objective was to characterize the otologic and audiologic findings in PS. The records of PS patients evaluated at our craniofacial center over a 30-year period were culled. Only patients with ...
Cohen Helen S - - 2010
Although computational models suggest the existence of canalithiasis and cupulolithiasis subtypes of benign paroxysmal positional vertigo (BPPV), these subtypes cannot be distinguished from each other based on characteristics of nystagmus. Therefore, although the subtypes probably exist more information is needed from each patient than is available without invasive procedures. Also, ...
Suzuki Masaaki - - 2010
The criteria have not yet been established for identifying the configuration of a pure tone audiogram constituting abnormal results that warrant further investigation. The purpose of this study was to determine the prevalence of acoustic neuroma associated with each configuration of the pure tone audiogram in patients with asymmetric sensorineural ...
Fiorino Francesco - - 2011
The objective of the study was to compare the outcomes of a series of diagnostic parameters in Ménière's disease (MD) patients with the extent of endolymphatic hydrops (EH) as shown by magnetic resonance imaging (MRI) performed after intra-tympanic gadolinium administration using 18 patients (13 males and 5 females, age 25-78 ...
Kushlinsky N E - - 2010
Comparative enzyme immunoassay of matrix metalloproteinases (MMP-2, -7, -9) and their tissue inhibitor-1 (TIMP-1) in the sera of 26 healthy individuals and 54 patients with primary osteal tumors before therapy revealed elevated TIMP-1 levels in the patients with classical central and periosteal osteosarcomas in comparison with the control. In patients, ...
Kerschner Joseph E - - 2010
To compare levels of middle ear (ME) MUC5AC expression in patients with otitis media (OM) with patients without OM. Mucin gene 5AC has been identified as a major secretory mucin in the ME and is fundamentally important in the development of ME mucoid effusions, hearing loss and also provides ME ...
Mazurek Birgit - - 2010
Tinnitus disturbs lives and negatively affects the quality of life of about 2% of the adult world population. Research has shown that the main cause of tinnitus is hearing loss. To analyze a possible association of the degree of hearing loss with the severity of tinnitus, we have performed a ...
Kingma C M - - 2011
Vestibular evoked myogenic potentials (VEMPs) were measured in 22 unilateral Menière patients with monaural and binaural stimulation with 250 and 500 Hz tone bursts. For all measurement situations significantly lower VEMP amplitudes were on average measured at the affected side compared to the unaffected side. Unilateral Menière patients have, in contrast ...
Büki Béla - - 2011
Presently, the unambiguous diagnosis of benign paroxysmal positioning vertigo (BPPV) requires the detection of positioning or positional nystagmus provoked by Dix-Hallpike (for vertical semicircular canals) or supine roll (for horizontal semicircular canals) manoeuvres, which indicates canalo- or cupolithiasis of affected semicircular canals. There are patients, however, in whom--despite typical complaints ...
Iino Yukiko - - 2010
Eosinophilic otitis media (EOM) is an intractable otitis media characterized by the presence of a highly viscous yellow effusion containing eosinophils. It mainly occurs in patients with bronchial asthma and is resistant to conventional treatments for otitis media. Here we discuss the role of IgE in the pathogenesis of EOM. ...
Hadjizacharia P - - 2011
OBJECTIVE: To determine the injury patterns, complications, and mortality after alcohol consumption in trauma patients. METHODS: The Trauma Registry at an American College of Surgeons (ACS) level I center was queried for all patients with a toxicology screen admitted between 1st January 2002 and 31st December 2005. Alcohol-positive (AP) patients ...
Fushiki Hiroaki - - 2010
This study demonstrates that the resolution period of spontaneous nystagmus (SN) may provide an indication of vestibular dysfunction on a particular day in the primary care setting. We aimed to predict canal paresis using fundamental observations of SN during the early stage of acute peripheral vestibular disorders. The study involved ...
Ungkanont Kitirat - - 2010
To find the association between the abnormalities of tympanic membrane characteristics and the hearing level in pediatric patients with otitis media with effusion. Sixty-three pediatric patients with otitis media with effusion had undergone ear examinations by pneumatic otoscopy to assess the color, transparency, mobility, fluid level and retraction of the ...
van Capelle Carine I - - 2010
Little information is available regarding the auditory function in Pompe patients. Hearing loss has been reported in classic infantile patients, but it is still unknown whether central nervous system involvement interferes with auditory function and whether enzyme replacement therapy can improve hearing. Auditory function has not been studied in children ...
Sughrue Michael E - - 2010
Little is known regarding meningiomas that primarily arise from the floor of the middle fossa as opposed to the sphenoid wing, the cavernous sinus, the anterior petrous ridge, or the lateral convexity dura. Given the relative paucity of literature addressing this disease entity, we review the University of California at ...
Sughrue Michael E ME Department of Neurological Surgery, University of California, San Francisco, 94143, - - 2011
Vestibular schwannomas (VSs) are benign lesions with an unpredictable natural history. Perhaps the greatest barrier to predicting which patients need treatment is our poor understanding of how these tumors cause hearing loss in the first place. In this case-control study, the authors investigated the relationship between preoperative hearing loss and ...
Büki Béla - - 2011
In the last several years, a promising new approach has been suggested in the therapy of Ménière's disease (MD): the low-dose intratympanic gentamicin therapy. By titrating the desired vestibular inhibition by single injections and infrequent administration, side effects concerning hearing can be held on an acceptably low level, while disease-related ...
Kisilevsky Vitaly E - - 2010
To evaluate the technical and functional results of 144 stapedotomies in patients with severe to profound hearing loss (SPHL) and to compare the success rate in this group with that of 1001 primary stapedotomies for mild to moderate hearing loss (MMHL). Retrospective chart review. Tertiary referral centre. The charts of ...
Sato Teruyuki - - 2010
HYPOTHESIS: The purpose of this histopathological study is to examine temporal bones of patients with cochlear otosclerosis adjacent to the round window or adjacent to the oval window as compared with healthy controls. BACKGROUND: It is unclear if the extent and site of otosclerosis affects the extent of damage to ...
Zhai Feng - - 2010
To compare the cochlear distribution of low-dose fluorescent gentamicin after intra-tympanic administration in guinea pig (GPs) with clinical data of low dose intra-tympanic gentamicin in patients with intractable vertigo. Purified gentamicin-Texas Red (GTTR) was injected intratympanically into GPs and the cochlear distribution and time course of GTTR fluorescence in outer ...
Maciaszczyk Katarzyna - - 2011
In systemic sclerosis (SSc), there may develop hearing and balance disorders as a result of the immune-mediated vasculitis and fibrosis in the inner ear. The objective of the study was evaluation of the hearing organ function in patients with SSc with relationship to duration of the disease and Raynaud phenomenon ...
Chau Justin K - - 2010
To determine the evidence for different etiologies of sudden sensorineural hearing loss (SSNHL) identified by clinical diagnostic tests in the adult population. Systematic literature review. Review of MEDLINE (1950-October 2009), EMBASE (1980-October 2009), and EBM Review databases in addition to manual reference search of identified papers. Randomized controlled trials, prospective ...
Brandt Michael G - - 2010
OBJECTIVE: This study reviewed the experience and outcomes of 1 surgical team (L.S.P., S.P.L.) using the transcrusal approach. METHODS:Ten-year retrospective review of 17 consecutive patients requiring transcrusal exposure of the petrous apex and upper brainstem was performed. The main outcome measures included hearing and facial nerve preservation as measured by ...
Munaro Gisiane - - 2010
Otoneurological evaluations are based on tests which investigate auditory and vestibular disorders, including brainstem evoked auditory potentials and vecto-electronystagmography. to describe the results from the otoneurological assessment of patients with vestibulocochlear complaints, normal hearing individuals and patients with hearing loss, and we will compare them to a control group. Cross-sectional, ...
Peyvandi Aliasghar - - 2010
Multiple sclerosis (MS) has numerous neurologic signs and symptoms, including hearing impairment. The reports concerning the type and severity of hearing loss in MS patients vary and little is known about an association of the disease characteristics with changes in hearing status. To find the otologic and neuro-otologic manifestations of ...
Rashad U M - - 2010
Benign paroxysmal positional vertigo is one of the commonest peripheral vestibular causes of vertigo. The particle repositioning manoeuvre (Epley's manoeuvre) has become the 'gold standard' treatment for this disorder. Benign paroxysmal positional vertigo can affect any age group but is commoner in older patients. Cervical spine problems (e.g. spondylosis and ...
Barros Camila Giacomo Carneiro - - 2010
The present study evaluated the effectiveness of electrotactile tongue biofeedback (BrainPort((R))) as a sensory substitute for the vestibular apparatus in patients with bilateral vestibular loss (BVL) who did not have a good response to conventional vestibular rehabilitation (VR). Seven patients with BVL were trained to use the device. Stimulation on ...
Silverstein Herbert - - 2010
OBJECTIVE: Understand the safety and outcomes of intratympanic gentamicin treatment in patients with M?ni?re's disease with normal hearing. STUDY DESIGN: Case series with chart review. SETTING: Tertiary referral center. SUBJECTS AND METHODS: A total of 224 patients with disabling M?ni?re's disease treated between May 1996 and June 2007 were grouped ...
Pfammatter Alain - - 2010
OBJECTIVE: The aim of this investigation was to determine if there is any association between the size of the canal dehiscences and the symptoms and signs of patients presenting with the superior semicircular canal dehiscence syndrome. STUDY DESIGN: Prospective multicenter study. SETTING: Tertiary referral center. PATIENTS: Twenty-seven patients, 14 females ...
Sergi B - - 2010
This study aimed to evaluate audiological and vestibular involvement in Fabry disease and the effects of enzyme replacement therapy with human alpha-galactosidase A. The study population comprised 20 patients (11 males, 9 females) aged 15-69 years (mean 39.7). Patients underwent a complete clinical and instrumental evaluation before starting and during ...
Rombaux Ph - - 2010
Olfactory loss is considered as idiopathic (IOL) when no cause can be found, neither on the basis of a standardized history nor a thorough clinical evaluation. Olfactory bulb volume (OB) has been shown to be decreased in patients with olfactory loss due to trauma, infections, or sinonasal disease. However, OB ...
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