Search Results
Results 301 - 350 of 1762
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Kumar Raj - - 2010
OBJECTIVE: To assess longitudinally the severity of diffuse axonal injury in the corpus callosum in patients with moderate traumatic brain injury (TBI) through quantitative diffusion tensor imaging and to correlate these changes with neuropsychometric tests (NPT) at 6 and 24 months after injury. DESIGN: Prospective longitudinal study. PARTICIPANTS: Sixteen patients ...
Rangarajan Kanchana - - 2010
Head injury, severe acidosis, hypothermia, massive transfusion and hypoxia often complicate traumatic coagulopathy. First line investigations such as prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen level, platelet count and D-dimer levels help in the initial assessment of coagulopathy in a trauma victim. To study the coagulation profile in ...
Winfield Robert D RD Department of Surgery, Laboratory of Inflammation Biology and Surgical Science, University of Florida College of Medicine, Gainesville, FL, - - 2010
Obesity has been demonstrated to alter a number of acute and chronic medical conditions. The effect of obesity on severely injured patients, however, remains incompletely defined. We sought to unravel potential physiologic and genomic alterations induced by obesity in severely injured blunt trauma patients. A retrospective review of clinical and ...
Lange Rael T RT University of British Columbia, Vancouver, BC, Canada. - - 2010
It is a common clinical perception that alcohol intoxication systematically lowers Glasgow Coma Scale (GCS) scores when evaluating traumatic brain injury (TBI). However, the research findings in this area do not uniformly support this notion. The purpose of this study is to examine the effects of blood alcohol level (BAL) ...
Lindsey Kimberly A - - 2010
The intent of this study was to ascertain whether multiple trauma patients with traumatic brain injury (TBI) had lower serum concentrations of potassium and phosphorus and required more aggressive supplementation than multiple trauma patients without TBI. Ventilator-dependent adult patients without renal impairment who were admitted to the trauma intensive care ...
Hassan Z - - 2010
Inhalation injury is a major cause of morbidity and mortality in thermally injured patients but is difficult to quantify. A number of parameters can be useful evaluating inhalation injury including bronchoscopy, PaO(2)/FiO(2) (P/F) ratio, and carboxyhaemaglobin (COHb) levels. Identification of markers that permit early detection of the degree of damage ...
Al-Khateeb Taiseer Hussain - - 2010
PURPOSE: To record the prevalence of anatomic variations and the associated symptoms of mineralized stylohyoid complex (MSHC) in a Jordanian sample, and to investigate the possible factors responsible for mineralization. PATIENTS AND METHODS: This study was conducted at the Dental Teaching Clinics of Jordan University of Science and Technology in ...
Jain Vinod - - 2009
Abnormal collagen metabolism is thought to play an important role in the development of primary inguinal and ventral hernia. The detection of an impaired collagen balance both in the tissue as well as in cultured fibroblasts underlines the suspicion that the development of hernia is likely to be implemented primarily ...
Batchinsky Andriy I - - 2009
Heart rate complexity (HRC) is an emerging "new vital sign" for critically ill and injured patients. Traditionally, 800-beat data sets have been used to calculate HRC variables, thus limiting their practical use in an emergency. We sought to investigate whether data set reductions diminish the use of HRC to predict ...
Menaker Jay - - 2009
BACKGROUND: We have previously demonstrated that pulmonary embolism (PE) can occur early and explain hypoxia immediately after injury. We hypothesized that an increased awareness of early PE would result in an increased incidence, an earlier diagnosis, and a decreased mortality of PE after injury. METHODS: The trauma registry identified patients ...
Mascia Luciana - - 2009
The presence of pulmonary dysfunction after brain injury is well recognized. Acute lung injury (ALI) occurs in 20% of patients with isolated brain injury and is associated with a poor outcome. The "blast injury" theory, which proposes combined "hydrostatic" and "high permeability" mechanisms for the formation of neurogenic pulmonary edema, ...
Becker Alexander - - 2010
Highly sensitive and accurate for the detection of injuries requiring intervention in haemodynamically unstable patients, FAST may underestimate intra-abdominal injuries in stable patients with blunt abdominal trauma. Diminished accuracy of ultrasound has been reported in different cohorts of multiple injured patients. We hypothesised that multiple injured patients with a high ...
Bauman Michael - - 2011
Background: The focused abdominal sonography in trauma (FAST) examination is a routine component of the initial work-up of trauma patients. However, it does not identify patients with retroperitoneal hemorrhage associated with significant pelvic trauma. A wide pubic symphysis (PS) is indicative of an open book pelvic fracture and a high ...
Ley Eric J - - 2009
BACKGROUND: The inability to mount tachycardia (T) after trauma-related hypotension is labeled relative bradycardia (RB). The objective of this study was to examine RB incidence and prognosis in a large cohort of patients. METHODS: The Los Angeles County Trauma System database, consisting of five Level I and eight Level II ...
Allard Christopher B - - 2009
BACKGROUND: Intracranial hemorrhage (ICH) is common in traumatic brain injury (TBI) and a major determinant of death and disability. ICH commonly increases in size and coagulopathy has been implicated in such progression. We investigated the association between coagulopathy diagnosed by routine laboratory tests and ICH progression. METHODS: Subgroup post hoc ...
Tandon Asheesh - - 2009
OBJECTIVE: The frequency and pattern of endocrine abnormalities among patients with traumatic brain injury have been the subject matter of very few studies. This study was intended to assess the pattern of endocrine dysfunction following severe head injury. METHODS: Severe head injury patients admitted to the Department of Neurosurgery, All ...
Molena Daniela - - 2009
With the increased use of chest computed tomography (CT) scan in the initial evaluation of major trauma, findings that were not seen on a chest radiograph (CXR) are increasingly identified. Pneumomediastinum (PM) seen on CXR in blunt trauma patients is considered worrisome for airway and/or esophageal injury. The purpose of ...
Ray A Andrew - - 2009
OBJECTIVES: Percutaneous nephrolithotomy is commonly performed in the prone position. Knowledge of renal anatomy and the relationship of adjacent organs is essential to minimize patient morbidity and iatrogenic organ injury. We present the anatomical basis for a prone-flexed modification to patient positioning and review the advantages and disadvantages of alternate ...
Barrios Cristobal - - 2009
The purpose of this study was to identify the utility of thoracic computed tomography (TCT) in blunt trauma patients with a normal admission chest radiograph (CXR). A retrospective study was performed of 200 consecutive blunt trauma patients who received both CXR and TCT. One hundred and forty-three patients had a ...
Sviri Gill E - - 2009
OBJECT: The aim of the present study was to evaluate the time course for cerebral autoregulation (AR) recovery following severe traumatic brain injury (TBI). METHODS: Thirty-six patients (27 males and 9 females, mean +/- SEM age 33 +/- 15.1 years) with severe TBI underwent serial dynamic AR studies with leg ...
Saggar Vineet - - 2009
Abnormalities of blood coagulation are frequently found in patients following traumatic brain injury. Exposure to thromboplastin, which is abundant in brain, plays an important role in initiating coagulopathy. Eighty patients of moderate-to-severe head injury were screened for platelet count, prothombin time (PT), activated partial thromboplastin time (a-PPTK), fibrinogen degradation product ...
Yaghoubian Arezou - - 2009
To determine whether a positive blood alcohol level (BAL) affects morbidity and mortality at a Level I trauma center, a retrospective review of trauma patients 18 years of age and older was performed. There were 7985 trauma patients and 8 per cent (645) had a positive BAL. BAL(+) patients had ...
Nicandri Gregg T - - 2010
A concerning number of patients referred to our clinic with knee dislocations have not been thoroughly evaluated for popliteal injury. The objective of this study is to present our experience and attempt to identify possible causes for this trend. Thirty-one consecutive patients with knee dislocations referred over a 1-year period ...
Kleindienst Andrea - - 2009
Neuroendocrine dysfunction following traumatic brain injury (TBI) has been described extensively. However, few studies are longitudinal and most lack subtle radiological, clinical, and repetitive endocrine assessment in the acute phase. Accordingly, we prospectively assessed neuroendocrine function in 71 patients after TBI. Injury was documented by a computed tomography (CT). During ...
Salim Ali - - 2009
HYPOTHESIS: Ethanol exposure is associated with decreased mortality in patients with moderate to severe traumatic brain injury. DESIGN: Retrospective database review. SETTING: Trauma centers contributing to the National Trauma Data Bank (NTDB). PATIENTS: Version 6.2 of the NTDB (2000-2005) was queried for all patients with moderate to severe traumatic brain ...
Pieretti-Vanmarcke Rafael - - 2009
BACKGROUND: Cervical spine clearance in the very young child is challenging. Radiographic imaging to diagnose cervical spine injuries (CSI) even in the absence of clinical findings is common, raising concerns about radiation exposure and imaging-related complications. We examined whether simple clinical criteria can be used to safely rule out CSI ...
Tauber Mark - - 2009
BACKGROUND: Low-dose acetylsalicylate acid (LDA) therapy is accepted as a major risk factor for intracranial hemorrhages (ICH) in head injuries. Coincidentally, patient admissions that might be indicated for in hospital observation of neurologic function causes increased health care costs. In the literature, there is no evidence concerning the incidence of ...
Solarino Biagio - - 2009
Conclusions. Patients affected by whiplash-associated disorder presented alterations of vestibular evoked myogenic potentials (VEMPs). VEMP testing may be an important 'forensic' diagnostic tool in the assessment of cervical spine injury. Objectives. The purpose of this prospective study was to evaluate changes in VEMPs in the assessment of whiplash injuries. Patients ...
Lee Sung-Woo - - 2009
OBJECTIVE: It is important for preventing hyperventilation so as to improve the outcomes of patients with severe traumatic brain injuries. End-tidal CO2 (Petco2) reflects arterial CO2 (Paco2), noninvasively and continuously. The aim of this study is to examine the concordance between Paco2 and Petco2 among adults presenting to the emergency ...
Sharma Om P - - 2009
Patients with the seat belt sign (SBS) from motor vehicle crashes (MVCs) are prone to specific regional injury patterns. Investigators at a Level 1 trauma center analyzed the incidence, clinical implications, and spectrum of regional injuries in patients injured in MVC over 2 years. SBS was seen in 11.3 per ...
Brook Olga R - - 2009
The purpose of our study was to review the significance of intra- and peripancreatic fluid in trauma patients who have no other signs of pancreatic injury. We propose that intra- and peripancreatic fluid may be the consequence of hypovolemic shock treated with hyperhydration when there is significant delay between injury ...
Park Sung Jun - - 2009
This study was conducted to investigate the correlation between the degrees of injury on brain magnetic resonance imaging (MRI) and the time interval to recovery of consciousness in patients with diffuse axonal injury. From January 2004 to December 2008, 25 patients with diffuse axonal injury were treated at our hospital. ...
Bitto Alessandra - - 2010
Chest trauma is frequently followed by pulmonary contusion and sepsis. High mobility group box-1 (HMGB-1) is a late mediator of severe sepsis that has been associated with mortality under experimental conditions. We studied HMGB-1 mRNA expression in patients with lung injury and its relationship with the severity of trauma and ...
Kornezos Ioannis - - 2010
Our objective is to underline the place of FAST (focus assessment by sonography for trauma) ultrasonography (US) in the investigation of blunt abdominal trauma. We retrospectively examined the ultrasound findings in 1,999 haemodynamically stable adult patients. These people were admitted to the emergency room (ER) for possible blunt abdominal trauma. ...
Kuchta J - - 2009
In this retrospective study, the authors analyze the frequency, anatomical distribution and the clinical outcome of 44 patients after severe head injury, with and without lesions of the corpus callosum (CC). 44 patients with severe head injury (GCS<9 on admission), who were admitted to the intensive care unit of the ...
Baker Andrew J - - 2009
Abstract In the treatment of severe traumatic brain injury (TBI), the choice of fluid and osmotherapy is important. There are practical and theoretical advantages to the use of hypertonic saline. S100B, neuron-specific enolase (NSE), and myelin-basic protein (MBP) are commonly assessed biomarkers of brain injury with potential utility as diagnostic ...
Rael Leonard T - - 2009
The amount of oxidative stress in patients with an isolated traumatic brain injury (ITBI) can be estimated by measuring several biochemical parameters, such as total antioxidants, lipid peroxidation, protein oxidation, and others. Unfortunately, measuring these parameters is time-consuming, impractical in a clinical setting, and may miss important factors contributing to ...
Muthialu Arpitha - - 2009
We describe a technique to position patients with severe kyphosis so the head is horizontal. The legs are lifted into the Trendelenburg position, and the patient is supported with straps similar to those of a parachute. Although the patient's legs are high above the head and jugular distension has been ...
Lögters Tim T - - 2009
Kynurenine, the major degradation product of tryptophan has been shown to directly damage tissues, but its possible contribution to posttraumatic morbidity is unknown. Here, we studied the kinetics of kynurenine in patients after major trauma and whether this correlates with the development of posttraumatic sepsis. Kynurenine and tryptophan levels of ...
Warner Keir J - - 2009
BACKGROUND: Etomidate is an induction agent used for the rapid sequence intubation (RSI) of trauma patients because of its favorable hemodynamic profile and rapid onset. However, recent studies have shown etomidate to decrease circulating cortisol concentrations, potentially influencing inflammation. We hypothesized that etomidate may alter the occurrence of acute respiratory ...
Jastrow Kenneth M KM - - 2009
BACKGROUND: Shock is a prime inciting event for postinjury multiple organ failure (MOF), believed to induce a state of injurious systemic inflammation. In animal models of hemorrhagic shock, early (< 24 hours) changes in cytokine production are an index of the systemic inflammatory response syndrome. However, their predictive value in ...
Lindvall Peter - - 2009
Seventy-one patients from northern Sweden were diagnosed with chronic subdural haematomas (CSDH) and treated at the Department of Neurosurgery at Umeå University Hospital over 12 months. Fifty-four patients with CSDH had a history of head trauma (trauma group), while 17 patients had no previous head trauma (non-trauma group). In the ...
Arbogast Steven D - - 2009
BACKGROUND: Clinicians depend on history given by the patients when considering the diagnosis of orthostatic hypotension. METHODS: Patients with a decrease in systolic blood pressure more than 60 mm Hg from baseline during a head-up tilt table test were included. They were classified according to their symptoms during the head-up ...
Rhodes Jonathan - - 2009
BACKGROUND: Cerebral contusions contain numerous leukocytes, and a temporal relationship exists among cerebral chemokine expression, leukocyte recruitment, and contusion enlargement. This would suggest a role for chemokines in contusion development. However, it has not been established if serum concentrations of chemokines such as interleukin-8 (IL-8) or monocyte chemoattractant protein-1 (MCP-1) ...
Bailitz John - - 2009
BACKGROUND: An estimated 10,000 Americans suffer cervical spine injuries each year. More than 800,000 cervical spine radiographs (CSR) are ordered annually. The human and healthcare costs associated with these injuries are enormous especially when diagnosis is delayed. Controversy exists in the literature concerning the diagnostic accuracy of CSR, with reported ...
Aarabi Bizhan - - 2009
OBJECT: This retrospective comparative cohort study was aimed at discovering the risk factors associated with subdural hygroma (SDG) following decompressive craniectomy (DC) to relieve intracranial hypertension in severe head injury. METHODS: Sixty-eight of 104 patients who had undergone DC during a 48-month period and survived > 30 days were eligible ...
Neil Michael J E - - 2009
Severe disturbance of potassium balance is a rare but life-threatening complication of therapeutic barbiturate coma. A 14-yr-old patient was treated with a thiopental infusion for management of increased intracranial pressure after severe head injury. The patient had persistent hypokalaemia during the thiopental infusion. On cessation of the infusion the patient ...
Marklund Niklas - - 2009
OBJECT: Damage to axons contributes to postinjury disabilities and is commonly observed following traumatic brain injury (TBI). Traumatic brain injury is an important environmental risk factor for the development of Alzheimer disease (AD). In the present feasibility study, the aim was to use intracerebral microdialysis catheters with a high molecular ...
Mauritz Walter - - 2009
OBJECTIVE: To investigate the outcome of brain trauma patients who had a Glasgow Coma Scale score (GCS) of 3 and bilateral fixed and dilated pupils (BFDP) in the field. METHODS: Between January 2001 and December 2005, 13 European centres enrolled patients with severe brain trauma. Data sets of all patients ...
Sloan Edward P - - 2009
BACKGROUND:: Hemoglobin solutions have demonstrated a pressor effect that could adversely affect hemorrhagic shock patient resuscitation through accelerated hemorrhage, diminished perfusion, or inadequate resuscitation. SETTING:: Data from two parallel, multi-center traumatic hemorrhagic shock clinical trials in 17 US Emergency Departments and 27 EU pre-hospital systems using DCLHb, a hemoglobin-based resuscitation ...
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