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Kosacka Monika - - 2009
INTRODUCTION: Cytokeratin (CK) 19 belongs to type I cytokeratins. CYFRA 21-1 is an assay which detects the soluble fragment of cytokeratin 19. OBJECTIVES: The aim of this study was to compare the CYFRA 21-1 serum level with cytokeratin 19 expression in tumor tissue. PATIENTS AND METHODS: The CK 19 expression ...
Arisan Elif Damla - - 2009
We estimated the circulating levels of adipocytokines such as adiponectin and leptin in nonobese nondiabetic prostate cancer (PCa) patients and compared the results with controls and benign prostate hyperplasia (BPH) patients. Fifty patients with PCa, 20 patients with BPH and 50 healthy volunteers were entered into the study. Their blood ...
van Renterghem Koenraad - - 2009
INTRODUCTION: In patients with minor lower urinary tract symptoms (LUTS), elevated prostate-specific antigen (PSA) levels and (multiple) negative multi-site biopsies, therapy decision is complex. Long-term outcome of a diagnostic transurethral resection of the prostate (TURP) in these patients needs to be determined. METHODS: We retrospectively evaluated patients with minor LUTS, ...
Serkin Faye B - - 2010
PURPOSE: To define the impact of discordant Gleason sum (GS) between prostate biopsy (Pbx) tissue and radical prostatectomy (RP) specimen among men initially diagnosed with Gleason 6 or 7 prostate adenocarcinoma. MATERIALS AND METHODS: We evaluated patients diagnosed with GS 6 or 7 and treated primarily with RP. We defined ...
Sztefko Krystyna - - 2010
We report the case of an 82-year old female patient admitted to the emergency department after fainting episode, low blood pressure, and arrhythmia. The patient reported a watery diarrhea of 3 weeks duration. Extremely high total creatinine kinase (CK) and CK-MB activity but normal troponin level were measured. Laboratory investigation ...
Miyoshi Toru - - 2009
BACKGROUND: Activin A, a member of the transforming growth factor-beta cytokine family, has been suggested to have a role in inflammation. We examined the serum level of activin A in patients with acute myocardial infarction (AMI) undergoing successful primary percutaneous coronary intervention (PCI). METHODS: The subjects were 30 AMI patients, ...
Tsai C-C - - 2009
To evaluate the relationship between oxidative stress and clinical evolution in patients with Graves' ophthalmopathy (GO). Thirty-one euthyroid GO patients and 25 healthy subjects participated in this study. Oxidative DNA damage was assessed by determination of the 8-hydroxy-2'-deoxyguanosine (8-OHdG) level in urine by ELISA. The relationship of oxidative DNA damage ...
Kumar Yogesh - - 2008
BACKGROUND: The currently available tumour markers used in the management of patients with colorectal metastases are of limited value. Tumour M2-pyruvate kinase (TuM2-PK), a tumour-associated isoenzyme of pyruvate kinase, is elevated in patients with gastrointestinal cancer. This study has measured TuM2-PK levels in patients before and after resection of colorectal ...
Tomita M - - 2008
BACKGROUND: The prognostic impact of serum carcinoembryonic antigen (CEA) levels and pleural lavage cytology (PLC) in female patients with non-small cell lung cancer (NSCLC) were examined. METHODS: A consecutive series of 122 women with NSCLC who underwent surgical resection and PLC were included in the study. RESULTS: The 5-year survival ...
Staubach Petra - - 2009
Patients with chronic spontaneous urticaria (CU) frequently exhibit increased levels of total IgE (tIgE). However, sensitisations to relevant allergens are rarely detected in CU patients by standard prick testing suggesting that CU symptoms, at least in some patients, may represent hypersensitivity reactions to less common allergens. The objective of this ...
Salmasi Amirali Hassanzadeh - - 2008
PURPOSE: We used current methods of screening for prostate cancer, digital rectal examination and serum prostate specific antigen as an initial assessment of risk in a young group of adult 46,XY patients affected by disorders of sex development. MATERIALS AND METHODS: Adult intersex patients older than 21 years, under long-term ...
Al Otaibi Mohammed - - 2008
BACKGROUND: Active surveillance (AS) with deferred treatment is an established management option for patients with prostate cancer and favorable clinical parameters. The impact of repeat biopsy after diagnosis was examined in a cohort of men with prostate cancer on AS. METHODS: In all, 186 men with prostate cancer with favorable ...
Hoering Antje A Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. - - 2008
Cancer therapies with mechanisms of action which are very different from the more conventional chemotherapies are now being developed. In this article, we investigate the performance of several phase III clinical trial designs, both for testing the overall efficacy of a targeted agent and for testing its efficacy in a ...
King Amber E - - 2008
To identify potential risk factors for the development of osteonecrosis of the jaw (ONJ) in patients receiving bisphosphonates, we conducted a MEDLINE search. We identified 44 English-language published case reports and case series describing 481 patients with bisphosphonate-related ONJ. Our review of these reports indicated that ONJ occurs more frequently ...
Drincic Andjela - - 2008
OBJECTIVE: To report the association of undetectable or very low prostate-specific antigen (PSA) concentrations with hypopituitarism. METHODS: We present a case series of 4 patients with low or undetectable PSA concentrations and associated panhypopituitarism and summarize the clinical presentation and pertinent laboratory and radiologic findings. We review related literature and ...
Kumar Virendra - - 2008
Results of the preliminary study on the evaluation of the role of magnetization transfer imaging (MTI) of prostate in men who had raised prostate-specific antigen (PSA) (>4 ng/ml) or abnormal digital rectal examination (DRE) are reported. MT ratio (MTR) was calculated for 20 patients from the hyper- (normal) and hypo-intense ...
Tuncel Altug - - 2008
OBJECTIVES: To investigate the effectiveness of disposable transrectal ultrasound needle guide in the prevention of possible infectious complications after transrectal prostate biopsy. METHODS: One hundred ninety-eight patients who underwent transrectal needle biopsy of the prostate were included in the study. Patients were randomly assigned into 2 groups; in group 1 ...
Stav Kobi - - 2008
OBJECTIVES: To evaluate the diagnostic value of saturation prostate biopsy in patients with prostate-specific antigen (PSA) greater than 10 ng/mL, PSA velocity greater than 0.75 ng/mL/year, free PSA ratio less than 0.2, and at least 3 sets of negative biopsy specimens. METHODS: Twenty-seven patients underwent the procedure with the use ...
Andron Mohammed - - 2008
OBJECTIVE: To evaluate the incidence of periprocedural creatine kinase-MB (CK-MB) release and its impact on longterm mortality in contemporary percutaneous coronary intervention (PCI) at a tertiary referral center. METHODS: Retrospective analysis of 4,958 patients undergoing PCI with deployment of at least 1 stent at our center between January 1, 2003 ...
Johnson Kristine E - - 2008
We describe what we believe is the first reported case of simultaneous highly invasive cutaneous and laryngopharyngeal zygomycosis in a non-neutropenic, nondiabetic but immunosuppressed patient with prostate cancer. An invasive fungal process was not suspected until late in the patient's hospital course; when it was, a tracheotomy and direct laryngoscopic ...
Nienhuis Mark B - - 2008
BACKGROUND: Although the prognostic significance of creatine kinase (CK) and creatine kinase-MB (CK-MB) after myocardial infarction has been established after thrombolysis or no reperfusion therapy, there is limited evidence of the prognostic importance after primary percutaneous coronary intervention (PCI). METHODS: In this prospective, observational study, individual data from all patients ...
Muto Satoru - - 2008
BACKGROUND: We evaluated the efficacy and feasibility of high-intensity-focused ultrasound (HIFU) for localized prostate cancer. METHODS: Seventy patients received HIFU using Sonablate((R)) 500 (Focus Surgery, IN, USA). In patients whose cancer was confined to only one lobe by multi-regional biopsies, total peripheral zone and a half portion of transitional zone ...
Langen Katja M - - 2008
PURPOSE: To quantify and describe the real-time movement of the prostate gland in a large data set of patients treated with radiotherapy. METHODS AND MATERIALS: The Calypso four-dimensional localization system was used for target localization in 17 patients, with electromagnetic markers implanted in the prostate of each patient. We analyzed ...
Bartoletti Riccardo - - 2009
BACKGROUND: Controversial data on modifications of prostate size, function and disease of spinal cord injury (SCI) patients has been previously reported. OBJECTIVE: An analytical observational cohort study on male SCI patients was planned in order to evaluate prostate gland growth, including benign prostatic hyperplasia in relation to the age of ...
Fernández Angel L - - 2008
The purpose of this study was to compare cardiac markers in the pericardial fluid and serum in order to evaluate preoperative myocardial injury. Thirty patients were divided into three groups. The first group (AVR; n=10) received an aortic valve replacement. The second group (SA; n=10) included patients with stable angina ...
Shigehara Kazuyoshi - - 2008
We investigated the incidence and characteristics of acute bacterial prostatitis after transrectal prostate biopsy, based on urine and blood cultures, treatment method, and outcome. Four hundred and fifty-seven patients who underwent transrectal prostate biopsy in our hospital between November 2003 and October 2006 were reviewed. These patients were treated with ...
Gulcelik Nese Ersoz - - 2008
Patients with polycystic ovary syndrome (PCOS) have an increased prevalence of metabolic syndrome (MBS). Hypoadiponectinemia is closely associated with MBS. The aim of our study was to evaluate the association of adiponectin levels with MBS in patients with PCOS. We studied 60 patients with PCOS and 60 age-matched control subjects. ...
Kikuta Ken-ichiro - - 2008
OBJECTIVE: To examine the relationship between asymptomatic microbleeds (MBs) and the occurrence of subsequent stroke in patients with moyamoya disease. METHODS: Beginning in October 2003, 50 consecutive patients with moyamoya disease were enrolled in a prospective study using 3-T magnetic resonance imaging. These patients were followed from the date of ...
Saito Eizo - - 2008
Intravenous immunoglobulin (IVIG) therapy was administered to 15 patients who were refractory to traditional steroid therapy [eight with polymyosis (PM), seven with dermamyosis (DM)] to evaluate its efficacy. Serum creatine kinase (CK) significantly decreased from week 1, and manual muscle test scores (MMT) and activities of daily living (ADL) significantly ...
Finsterer Josef - - 2008
OBJECTIVES: This retrospective study aimed to find out how often CK is elevated in left-ventricular hypertrabeculation/noncompaction (LVHT), how often CK-elevation is due to neuromuscular disorders (NMDs), other cardiac disease, or causes other than cardiac or NMD, and how often CK-elevation is associated with troponin-T-positivity. METHODS: Electronic records from all LVHT-patients ...
Kalluri Meena - - 2007
BACKGROUND AND AIM: CA 125 is a glycoprotein expressed by a variety of tissues of mesothelial origin. It has classically been associated with ovarian carcinoma. It has also been reported to be elevated in certain granulomatous conditions. We describe a patient with sarcoidosis and an elevated serum CA 125 level ...
Qiao Xiao-zhi - - 2007
To investigate the relationship between serum resistin level and acute coronary syndrome (ACS) or stable angina pectoris (SAP). Sixty-five patients, with coronary artery disease, were enrolled and divided into three subgroups: acute myocardial infarction (AMI), unstable angina pectoris (UAP) and SAP, and 26 healthy people were recruited as controls in ...
Domingo-Domenech J - - 2008
Human epidermal growth factor receptor 2 (HER2) overexpression has been linked to hormone-independent prostate cancer (HIPC) progression. Its clinical value and correlation with therapy is not defined. Patients with HIPC treated with docetaxel (Taxotere) were prospectively tested for serum HER2 extracellular domain (ECD) by immunoanalysis. HER2 was determined by immunohistochemistry ...
van den Heuvel Michel M - - 2008
BACKGROUND: Serum markers have been tested in patients with malignant effusions for their ability to differentiate malignant pleural mesothelioma from other causes. We have assessed three different serum markers and report our findings in a series of patients with different thoracic malignancies and a group of healthy controls. METHODS: A ...
Medina Hector M - - 2007
Periprocedural myonecrosis, as evidenced by elevated creatine kinase-myocardial bound (CK-MB) levels, occurs in up to 25% of patients undergoing percutaneous coronary intervention (PCI) and has been linked with an increased risk of adverse short- and long-term clinical outcomes. Such myonecrosis arises from three main pathophysiological mechanisms: procedure-related complications, lesion-specific characteristics ...
Kanamaru Hiroshi - - 2007
BACKGROUND: The purpose of this study was to determine the appropriate recommendations for weaning off cardiopulmonary support (CPS) in children with fulminant myocarditis. METHODS AND RESULTS: Four consecutive patients diagnosed with fulminant myocarditis who were treated with CPS were enrolled (mean age: 9 years). The relationships between timing of weaning ...
Pierorazio Phillip M - - 2007
OBJECTIVES: To more clearly elucidate the relationship between prostate volume (PV) and prostate cancer parameters. METHODS: The Urologic Oncology Database was reviewed. A total of 3460 patients had undergone radical prostatectomy from 1988 to 2006. Of these, 2600 with complete data were included in the study and were stratified by ...
McCain Keith R - - 2007
BACKGROUND: There are 4 centrally acting cholinesterase inhibitors (CA-ChEI) available in the US: tacrine, galantamine, rivastigmine, and donepezil. Documented clinical experience involving exposure to these agents is limited. The lack of information makes decisions involving excessive or unintended CA-ChEI exposure difficult. OBJECTIVE: To assess the effects, demographics, and outcomes of ...
Davis Melinda V - - 2007
OBJECTIVES: Cricopharyngeal achalasia (CA) can be defined as inadequate opening of the cricopharyngeus muscle (CPM) resulting in dysphagia. Myosin heavy chain (MHC) isoform fiber type composition and size are key determinants of muscle function. These parameters have not been described in CA. It is hypothesized that there is a difference ...
Bulbul Muhammad A - - 2007
This study aims to evaluate the accuracy of transrectal ultrasound (TRUS) guided prostate biopsies in predicting pathological grading and tumour distribution in the final pathological specimen of patients who underwent radical prostatectomy for clinically localized prostate cancer. The study ultimately aims to gain more understanding of the pathological behaviour of ...
Laji, I; ;
Objectif : Etudier les aspects épidémiologiques, diagnostiques et thérapeutiques des tumeurs primitives de l'urètre chez l'homme. Patients et méthodes : Il s'agit d'une étude rétrospective portant sur 7 cas de tumeurs de l'urètre masculin colligés dans notre institution sur une période de 16 ans (1989-2005). Plusieurs paramètres ont été analysés ...
Kumar Virendra - - 2007
Determination of the apparent diffusion coefficient (ADC) of the prostate in men (n = 60) with raised prostate-specific antigen (PSA) or an abnormal digital rectal examination (DRE) prior to transrectal ultrasound (TRUS) guided biopsy using endorectal DWI is reported. Patients were categorized into different groups based on their PSA levels. ...
Christoforidis Athanasios - - 2007
Increased life expectancy in patients with homozygous beta-thalassaemia consequently increases the risk for neoplastic diseases. This study was conducted to assess the levels of five common tumour markers in thalassaemic patients and to investigate possible correlations to demographical, clinical and laboratory data. Eighty-five patients (44 female and 41 male) with ...
Tumminello Francesca M - - 2008
The clinical significance of serum cathepsin K and cystatin C was assessed in patients with breast cancer (BCa) or prostate cancer (PCa) with confined disease (M0) or bone metastasis (BM). Cathepsin K and cystatin C circulating levels were determined by ELISAs in 63 cancer patients, in 35 patients with nonmalignant ...
Gladman Dafna D - - 2007
OBJECTIVE: To determine whether the axial measures used in primary ankylosing spondylitis (AS) were reproducible for both AS and psoriatic arthritis (PsA) with axial disease. METHODS: A group of 20 rheumatologists from 11 countries with expertise in spondyloarthritis (SpA) met for a combined physical examination exercise to assess 10 patients ...
Koutouzis Michael - - 2007
The presence, cause, and clinical significance of elevated cardiac troponin I in patients with acute lower limb ischemia is yet unknown. Forty-six patients (20 men [43%]; mean age 72 +/- 10 years, range 42 to 92) with acute lower limb ischemia were enrolled in this study. Serial creatine kinase (CK), ...
Al-Taheini Khalid - - 2007
Prostatic calculi, though common in adult men, are rare in children. We report three cases of pediatric prostatic calculi seen at our clinic that were associated with hypercalciuria and elevated urinary calcium/creatinine ratios. The patients had no symptoms from their prostatic calcification, but one patient had recurrent symptomatic renal calculi. ...
Kim T - - 2008
OBJECTIVE: Data concerning faecal incontinence (FI) in men are lacking. The aim of this study was to evaluate the historical aetiology and contrast aetiologies in younger and older men suffering from FI. METHOD: After institutional review board approval, a retrospective chart review was undertaken of all patients with FI seen ...
Incorvaia Lorena - - 2007
BACKGROUND: The clinical significance of the circulating levels of activin A and matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) was investigated in patients with breast cancer (BC) or prostate cancer (PC) with (M1) or without (M0) bone metastasis. PATIENTS AND METHODS: MMP-2, MMP-9 and activin A blood concentrations were measured by ...
Bozbas Huseyin - - 2007
Serum cardiac enzyme elevation after percutaneous coronary intervention (PCI), a relatively common complication, is a prognostic determinant of long-term outcome in patients who undergo these procedures. Statins are postulated to reduce such complications. This study investigated the short-term effects of pravastatin on serum creatine kinase myocardial isoform (CK-MB) and serum ...
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