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Christensen John D JD Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases (J.D.C., E.C., P.G., K.I.R., R.J.B.), National Institute of Dental and Craniofacial Research (M.T.C., R.I.G.), Nuclear Medicine Department, Clinical Center (J.C.R.), National Institutes of Health, Bethesda, Maryland 20892; and Joslin Diabetes Center (A.O.L.), Brookline, Massachusetts - - 2014
Context: Leptin alters bone and mineral metabolism in rodents, but this has not been verified in humans. Patients with congenital generalized lipodystrophy (CGL) have low leptin due to deficient adipose mass and serve as models of leptin deficiency and replacement. Objective: To study the effects of recombinant human methionyl leptin ...
Takami Yoshiyuki Y Department of Cardiovascular Surgery, Kansai Medical University, Takii Hospital, 10-15 Fumizono-cho, Moriguchi, 570-8507, Japan, - - 2014
In hemodialysis (HD)-dependent patients, secondary hyperparathyroidism induces cardiac hypertrophy. This study investigated whether parathyroid hormone (PTH) levels affect the degree of left ventricular (LV) mass regression in HD patients after aortic valve replacement (AVR) for aortic stenosis (AS). We retrospectively obtained preoperative and 2-year postoperative echocardiography and intact PTH measurements ...
Lu Jun Ling JL Division of Nephrology, University of Tennessee Health Science Center, Memphis, - - 2014
Obesity is associated with higher mortality in the general population, but this association is reversed in patients on dialysis. The nature of the relationship of obesity with adverse clinical outcomes in nondialysis-dependent CKD and the putative interaction of the severity of disease with this association are unclear. We analyzed data ...
Christofolini Juliana J Faculdade de Medicina do ABC, Santo André, SP, - - 2014
Objective : To investigate the influence of anthropometric indices on seminal parameters. Methods : Men who underwent treatment for conjugal infertility during the period of October, 2011, to March, 2012, were randomly selected. Patients with any prior diseases related to sperm alterations were excluded. Patients were submitted to an anthropometric ...
Elgafy Hossein - - 2014
Several methods for C1-C2 stabilization have been described in the literature. These include C1-C2 transarticular screws and C1 lateral mass screws. In patients with aberrant anatomy such as a high-riding VA or the presence of an arcuate foramen at C1 there exists a higher risk of VA injury. This may ...
Owczarczyk-Saczonek Agnieszka A Department and Clinic of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, Municipal Hospital, Olsztyn, Poland. Head of Department: Prof. Waldemar Placek MD, - - 2014
Many recent epidemiological studies have shown the influence of treatment with anti-TNF-α on body mass of patients with psoriasis but there are no reports in the literature on the influence of ustekinumab on that parameter. To review the effect of ustekinumab therapy on body weight in patients with psoriasis. The ...
Staab Wieland W Institute for Diagnostic and Interventional Radiology, Heart Center, University Medical Center Göttingen, Göttingen, Germany, - - 2014
We sought to evaluate the diagnostic accuracy of contrast-enhanced cardiac magnetic resonance (CMR) imaging for the detection of intracardiac masses and thrombus formation in patients with history of coronary artery disease (CAD) in comparison to transthoracic echocardiography (TTE) under clinical routine conditions. 171 patients with history of CAD (89 male, aged ...
Waterfield John J Walsall Manor Hospital, Walsall, - - 2014
A 27-year-old man with a history of migraines, epilepsy and pulmonary stenosis presented to the emergency department with symptoms of vomiting, headache, visual disturbance and problems with balance. The team considered the possibility of intracranial pathology and an urgent CT head with contrast showed what appeared to be a large ...
Liu Zhijun Z Ultrasound Department, Shengjing Hospital, China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning, China, - - 2013
To assess the role of transabdominal ultrasound after oral administration of an echoic cellulose-based gastric contrast agent (TUS-OCCA) for detection and characterization of small gastric subepithelial masses (≤3 cm) by comparison with endosonography (EUS). Ninety-five patients with small gastric subepithelial masses detected by gastroscopy examination were enrolled. For each patient, TUS-OCCA ...
Gouérant Sophie - - 2013
Few data are published on docetaxel toxicity in obese patients. All obese patients (n=100) treated for early breast cancer during three consecutive years at our Institution, were retrospectively investigated. The same number of non-obese patients was randomly selected and used as controls. We assessed the factors predictive of the relative ...
Puig Teresa T Servicio de Epidemiología Clínica, Hospital de la Santa Creu i Sant Pau, IIb-Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address: - - 2014
To analyze the association between higher body mass index and waist circumference, and the prognostic values of both indicators in total and cardiac mortality in patients with chronic heart failure. The study included 2254 patients who were followed up for 4 years. Obesity was classified as a body mass index ...
Puig Teresa - - 2013
To analyze the association between higher body mass index and waist circumference, and the prognostic values of both indicators in total and cardiac mortality in patients with chronic heart failure. The study included 2254 patients who were followed up for 4 years. Obesity was classified as a body mass index ...
Lan Yue - - 2013
Restoration of both normal movement of the pelvis and centre of mass is a primary goal of walking rehabilitation in post-stroke patients because these movements are essential components of effective gait. The aim of this study is to quantitatively analyze the effect of ankle-foot orthosis on walking ability, and to ...
Djer Mulyadi M MM Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, - - 2013
Aim: to assess for a correlation between T2*CMR with LV function and mass in thalassemic patients with iron overload. Methods: a cross-sectional study on thalassemic patients was conducted between July and September 2010 at Cipto Mangunkusumo and Premier Hospitals, Jakarta, Indonesia. Clinical examinations, review of medical charts, electrocardiography, echocardiography, and ...
Navve Daniella - - 2013
Objectives- The whirlpool sign is used as a sonographic marker for adnexal torsion. The aims of this study were to describe the location of the whirlpool sign (lateral or medial to the ovary) and to evaluate the clinical importance of the location. Methods- : Thirty patients with a confirmed surgical ...
Tang Shaoshan - - 2013
The purpose of this study was to evaluate contrast-enhanced ultrasonography (CEUS) as a modality for diagnosing perforation of the gallbladder (GB) and pericholecystic hepatic abscess. This retrospective study comprised 6 patients with acute cholecystitis and GB perforation plus pericholecystic hepatic abscess who underwent conventional US and CEUS imaging. The following ...
Regazzoni Luca - - 2012
Abstract - The aim of the present work was to monitor the covalent modifications of human serum albumin (HSA) in end stage renal diseases (ESRD) non diabetic patients, before and after hemodialysis (HD), by direct infusion electrospray mass spectrometry (ESI-MS). Human serum samples were collected from healthy subjects (n = ...
Degli Esposti Simona - - 2012
To evaluate the spatial distribution and total amount of macular pigment (MP) in patients with idiopathic macular telangiectasia type 2 (MacTel) compared to healthy subjects. Totals of 53 MacTel patients and 38 normal subjects underwent macular pigment optical density (MPOD) measurement using a 2-wavelength autofluorescence (2-AF) technique. The peak MPOD ...
Si Hongwei - - 2012
PURPOSE: The Gates-based renography (gGFR) and plasma-based clearance rate (pGFR) are conventionally corrected with body surface area (BSA). Limited studies indicated that the lean body mass (LBM) might be better than BSA in correcting pGFR. Therefore, we suggest that LBM is also better in correcting gGFR and improve the correlation ...
Mosli Hisham A - - 2012
To examine the relationship between the body mass index and the size of renal stones in a group of patients with urolithiasis. One-hundred seventy-three patients with renal stones were enrolled. Body mass index was calculated on the basis of height and weight measurements, and stone size was either measured accurately ...
Fuchs Susanne I - - 2012
BACKGROUND: Volumetric capnography reflecting the course of CO(2)-exhalation is used to assess ventilation inhomogeneity. Calculation of the slope of expiratory phase 3 and the capnographic index (KPI(v)) from expirograms allows quantification of extent and severity of small airway impairment. However, technical limitations have hampered more widespread use of this technique. ...
Lazard Diane S - - 2012
BACKGROUND: The purpose of this prospective bicentric study was to investigate the course of serum calcium (Ca) and phosphorus (Phph) after total/completion thyroidectomy to establish a reliable and cost-effective strategic algorithm to detect patients at risk for postoperative hypocalcemia. METHODS: This observational study included 136 patients. Serum Ca and Phph ...
Salinas Maria M Department of Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, Alicante, Spain. - - 2012
Total bilirubin tests are individually inexpensive but can result in huge costs to healthcare systems worldwide, because they are very commonly requested. The main objective of this study was to evaluate the diagnostic accuracy of the icteric index, a test with zero reagent cost, as a preliminary biomarker to decide ...
Abbasi Amanullah - - 2012
Objective: To determine the association of serum cholesterol levels with Child-Pugh class in patients with decompensated chronic liver disease due to viral hepatitis. Study Design: Cross-sectional analytical study. Place and Duration of Study: Jinnah Postgraduate Medical Centre, Karachi, Medical Unit-III, Ward-7 from June to December 2010. Methodology: Consecutive patients attending ...
Aslam Muhammad Z - - 2012
Objectives:  Detrusor myectomy is a recognized method of bladder augmentation for treating refractory detrusor overactivity. Herein we report the long-term outcomes of this procedure at the University Hospital of Wales in Cardiff, UK. Methods:  Detrusor myectomy was carried out in 33 patients (7 males, 26 females) with urodynamically proven detrusor ...
Yoshimi Ryusuke - - 2012
OBJECTIVES: Although "clinical remission" has been a realistic goal of treatment in rheumatoid arthritis (RA), there is evidence that subclinical synovitis is associated with ongoing structural damage even after clinical remission is achieved. In the study reported here, we assessed whether ultrasonography (US) can predict progressive joint destruction during clinical ...
Gansera Brigitte - - 2012
Background The occurrence of severe carotid artery disease in more than 12% of patients requiring coronary artery bypass grafting (CABG) results in a discrepancy concerning best treatment for both diseases. We reviewed the early outcome of patients with CABG and/or valve replacement (VR) and simultaneous carotid endarterectomy (CEA).Methods We retrospectively ...
Markou Nikolaos - - 2012
OBJECTIVES: Available data on colistin pharmacokinetics in patients undergoing continuous renal replacement therapy (CRRT) are limited. Our aim was to study colistin pharmacokinetics in critically ill patients treated with colistin methane sulphonate for Gram-negative sepsis and undergoing continuous venovenous haemodiafiltration for acute renal failure. PATIENTS AND METHODS: Three patients were ...
Padovani Rosália P - - 2012
Background: Current management guidelines suggest that 6-12 months after total thyroidectomy and radioactive iodine remnant ablation (RAI-RA), patients with differentiated thyroid cancer should be re-evaluated with serum thyroglobulin (Tg) and neck ultrasonography to assess the efficacy of initial treatment and to guide subsequent management. However, if serum Tg levels can ...
Sampaio M S - - 2012
Background and Objectives: The control of hyperphosphatemia is an unmet need in dialysis care. Compared to conventional hemodialysis (cHD), extended hemodialysis (eHD) appears to more easily control blood phosphate levels in chronically dialyzed patients. Here, we sought to compare eKT/V-matched cHD and eHD procedures in order to quantify the contribution ...
Ashizawa M - - 2012
Hyperbilirubinemia in the early phase after allogeneic hematopoietic SCT (HSCT) is due to various causes. One of the most important causes of hyperbilirubinemia is veno-occlusive disease/sinusoidal obstructive syndrome (VOD/SOS). However, the prognosis of patients who are clinically diagnosed as SOS varies. We retrospectively evaluated 82 patients who underwent their first ...
Shishido Takayoshi - - 2012
Background/Aims: The usefulness of capsule endoscopy (CE) and of double-balloon endoscopy (DBE) for detection of small-bowel lesions is widely accepted. We compared CE- and DBE-based detection of small-bowel lesions in patients with obscure gastrointestinal bleeding (OGIB) who underwent total enteroscopy by both CE and DBE. Methodology: One hundred eighteen consecutive ...
Nikolaou Vassilios S - - 2012
We aimed to investigate the effect of metal ions on the semen of males of child fathering age with metal-on-metal (MM) total hip arthroplasty (THA). Semen was collected form 11 patients with MM THA and 5 control of comparable age. Cobalt and chromiun concentrations were measured in both the seminal ...
Lazarus Jayam P - - 2012
We aimed to study the voice profiles of patients with Parkinson's disease (PD) and correlate the profiles with disease severity. A total of 133 patients with PD were recruited. Patients were divided into two groups: Group 1 with a Unified Parkinson's Disease Rating Scale (UPDRS) score of ⩽45; and Group ...
Testai Fernando D - - 2012
BACKGROUND AND PURPOSE: The purpose of this study was to investigate changes in the cerebrospinal fluid sphingolipid profile in patients with subarachnoid hemorrhage in relation to the occurrence of symptomatic vasospasm and outcome at hospital discharge. METHODS: The ceramide profile in the cerebrospinal fluid was determined by mass spectrometry in ...
Weier Katrin - - 2012
Cerebellar dysfunction is an important contributor to disability in patients with multiple sclerosis (MS), however, few in vivo studies focused on cerebellar volume loss so far. This relates to technical challenges regarding the segmentation of the cerebellum. In this study, we evaluated the semi-automatic ECCET software for performing cerebellar volumetry ...
Vuillerot Carole - - 2012
OBJECTIVES: To study the responsiveness (sensitivity to change) of the Motor Function Measure in detecting change in neuromuscular disease patients with the intent of using this Measure in future clinical trials. DESIGN: Prospective cohort observational study. SETTING: Inpatient and outpatient facilities for follow-up and treatment of neuromuscular diseases. PARTICIPANTS: Patients ...
Lazoura O - - 2012
PURPOSE: The aim of the present study was to correlate computed tomography appearances with clinical severity and outcome using a total lung disease (TLD) score in patients with acute respiratory distress syndrome (ARDS) related to influenza A H1N1 infection. MATERIALS AND METHODS: Chest computed tomographic scans of 33 patients admitted ...
Carne Christopher A - - 2012
ObjectivesTo conduct a case-control study of abnormalities in the semen of genitourinary (GU) medicine clinic attendees compared with general practice (GP) controls and in patients with asymptomatic and symptomatic non-specific urethritis (NSU) before and after the urethritis resolves.MethodsRates of semen abnormalities were compared between the different groups (19 with symptomatic ...
Iwasaki Masaki - - 2012
Object Corpus callosotomy is usually intended to alleviate-not to achieve total control of-epileptic seizures. A few patients experience complete seizure control after callosotomy, but the associated clinical factors are unknown. The object of this study was to investigate clinical factors associated with long-term seizure remission after total corpus callosotomy in ...
Procopet Bogdan - - 2012
BACKGROUND: Transjugular liver biopsy (TJLB) is usually performed when a percutaneous liver biopsy (PLB) is contraindicated. TJLB is an invasive procedure and the patient's tolerance may be variable. AIM: To compare patient tolerance and quality of the biopsy sample between PLB and TJLB. PATIENTS AND METHODS: A total of 143 ...
Bosker B H - - 2012
Peri-articular soft-tissue masses or 'pseudotumours' can occur after large-diameter metal-on-metal (MoM) resurfacing of the hip and conventional total hip replacement (THR). Our aim was to assess the incidence of pseudotumour formation and to identify risk factors for their formation in a prospective cohort study. A total of 119 patients who ...
Etemadifar Masoud - - 2012
Early-onset multiple sclerosis (EOMS) is defined as the first presentation of symptoms in childhood (before the age of 16 years). EOMS occurs in about 0.4% to 10.5% of multiple sclerosis (MS) patients. In this retrospective population-based study we aimed to describe the clinical/paraclinical details and frequency of epileptic seizures in ...
Guiraud Thibaut - - 2012
The aim of the study is to compare, in coronary artery disease patients, physical activity (PA) assessed with the Dijon Physical Activity Questionnaire (DPAQ) and the true PA objectively measured using an accelerometer. Seventy patients wore an accelerometer (MyWellness Key actimeter) throughout 1 week after a cardiac rehabilitation program that ...
De Nunzio Cosimo - - 2012
PURPOSE: To externally validate the performance characteristics of the Briganti's risk stratification tool for baseline staging bone scan in patients with newly diagnosed prostate cancer (PCa). METHODS: From 2009 onwards, a consecutive series of patients with PCa were enrolled. All patients were staged to evaluate the presence of bone metastasis ...
Stephens Linda Ruth - - 2012
Introduction Malrotation is a common abnormality, often diagnosed in the neonatal period. Symptoms may be nonspecific and clinical signs of volvulus are often only seen in the late stages when there has been significant ischemic insult to the bowel. The gold standard diagnostic investigation is the upper gastrointestinal (UGI) contrast ...
Duun-Henriksen Jonas - - 2012
Automatic detections of paroxysms in patients with childhood absence epilepsy have been neglected for several years. We acquire reliable detections using only a single-channel brainwave monitor, allowing for unobtrusive monitoring of antiepileptic drug effects. Ultimately we seek to obtain optimal long-term prognoses, balancing antiepileptic effects and side effects. The electroencephalographic ...
Lurz Philipp - - 2012
The goal of this study was to assess the diagnostic performance of cardiac magnetic resonance (CMR) compared with endomyocardial biopsy in patients with suspected acute myocarditis (AMC) and chronic myocarditis (CMC). Several studies have reported an encouraging diagnostic performance of CMR in myocarditis. However, the comparison of CMR with clinical ...
Anastasiou Olympia E - - 2012
Context:Hypocalcemia, transient or permanent, represents a common complication after total thyroidectomy, but data on the secretory capacity of the parathyroid glands in thyroidectomized patients without clinical or biochemical hypocalcemia are limited.Study Design:To address this issue, we studied the parathyroid response to acute hypocalcemia induced by iv infusion of sodium bicarbonate ...
Papayannis C E - - 2012
OBJECTIVE: To describe clinical features of epilepsy secondary to Malformation of Cortical Development (MCD) in a series of adult patients. MATERIALS AND METHODS: We searched our database for all cases with confirmed epilepsy and MCD and included in the study only those with complete data. Mean age, sex, age at ...
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