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Fukae Jun J Department of Rheumatology, Hokkaido Medical Center for Rheumatic Diseases, Faculty of Health Science, Hokkaido University and Department of Medicine II, Hokkaido University Graduate School of Medicine, Sapporo, - - 2014
Objective. In this study we investigated the relationship between synovial vascularity (SV) and structural alteration of finger joints in patients with RA and long-term sustained clinical low disease activity (CLDA).Methods. RA patients with CLDA of >2 years (minimum 1 year of CLDA for study entry plus 1 year of observation) ...
Ristić Aleksandar J AJ Center for Epilepsy and Sleep Disorders, Neurology Clinic, Clinical Center of Serbia, Belgrade, - - 2014
An altered metal and electrolyte profile has been implicated in the pathologic mechanisms of chronic epilepsy; however, no study has comprehensively measured hippocampal concentrations of these elements in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (mTLE-HS). We therefore analyzed hippocampi of 24 patients with drug-resistant mTLE-HS (mean age ...
Ranucci Giusy - - 2014
Wilson's disease (WD) evolves rapidly and is fatal if untreated. The treatment of WD patients with mild liver disease is not clearly defined. To address this issue, we evaluated long-term outcomes of three treatment regimens (D-penicillamine, zinc or both) in patients diagnosed in childhood. We retrospectively evaluated efficacy, compliance and ...
Reito Aleksi A Coxa Hospital for Joint Replacement, P.O. Box 652, 33101, Tampere, Finland, - - 2014
Conventional follow-up methods are not sufficient to identify adverse soft tissue reactions in patients with metal-on-metal hip replacements. The national guidelines regarding metal ion measurements are debatable. The aims of our study were to investigate (1) if there is a clinically significant change in whole blood (WB) cobalt (Co) or ...
Hou Jia-Woei JW Department of Pediatrics, Cathay General Hospital, Taipei, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan. Electronic address: - - 2014
Maple syrup urine disease (MSUD) is an autosomal recessive aminoacidopathy secondary to an enzyme defect in the catabolic pathway of the branched-chain amino acids (BCAAs: leucine, isoleucine, and valine). Accumulation of their corresponding keto-acids leads to encephalopathy if not treated in time. A newborn male patient was suspected to have ...
Kim Jeong Eun JE Department of Dermatology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, 138-736, - - 2014
Zinc deficiency in patients with atopic dermatitis (AD) and the use of zinc supplementation is still controversial. We measured hair zinc levels in 58 children with AD and 43 controls (age range 2-14 years). We also investigated the efficacy of oral zinc supplementation in AD patients with low hair zinc ...
Geletzke Abby K AK Department of Surgery,College of Medicine, The Pennsylvania State University, 500 University Drive, H047, P.O. Box 850, Hershey, PA, 17033-0850, - - 2013
To determine the prevalence of low-grade inflammation, micronutrient imbalances and associated clinical profiles in patients being evaluated for complex abdominal hernia repair. Review of 127 consecutive adult patients for evaluation of complex ventral hernias from January 2012 to March 2013. Records were analyzed to determine the prevalence and correlations of ...
Jang Ji Young JY Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of - - 2013
The authors designed this study to determine how serum selenium and zinc affect the outcomes of critically ill surgical patients. The medical records of 162 patients admitted to a surgical intensive care unit (ICU) from October 2010 to July 2012 and managed for more than 3 days were retrospectively investigated. ...
Barbe Michael T - - 2013
Patients with Parkinson's disease (PD) and freezing of gait (FOG) (freezers) demonstrate high gait variability. The objective of this study was to determine whether freezers display a higher variability of upper limb movements and elucidate if these changes correlate with gait. We were the first group to compare directly objectively ...
Tsutsumi Rie R Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima, Tokushima 770-8503, Japan. Electronic address: - - 2014
Patients with renal failure often experience decreased serum zinc that remains uncorrected after dialysis. A complication of this depletion is taste impairment, which can detrimentally influence diet and nutrition. However, because more than half of all serum zinc is bound to albumin, we hypothesized that normalizing serum zinc to albumin ...
Tanaka Akihito - - 2013
<bold><italic>Purpose:</italic></bold> The usefulness of skin perfusion pressure (SPP) measurement in the assessment of critical ischemia of the lower limb has previously been established. This study investigated whether finger SPP measurement is useful to evaluate hypoperfusion distal to arteriovenous vascular access in dialysis patients. <bold><italic>Methods:</italic></bold> Seventeen asymptomatic hemodialysis patients with upper ...
Filler Guido - - 2013
In end-stage chronic kidney disease (CKD), pediatric nephrologists must consider the homeostasis of the multiple water-soluble ions that are influenced by renal replacement therapy (RRT). While certain ions such as potassium and calcium are closely monitored, little is known about the handling of trace elements in pediatric dialysis. RRT may ...
Molenaar H M Ties - - 2013
When interventions to the hand are aimed at improving function of specific fingers or the thumb, the RIHM (Rotterdam Intrinsic Hand Myometer) is a validated tool and offers more detailed information to assess strength of the involved joints besides grip and pinch measurements. In this study, strength was measured in ...
Lieberman Abraham - - 2013
Abstract Although, the tremor of Parkinson's disease (PD) usually, but not always, differs from essential tremor (ET), there is no simple bedside test to distinguish PD from ET. We believe we have made such an observation. We studied 50 consecutive tremor-dominant PD patients (mean age: 63.4 years; mean disease duration: 4.9 years) ...
Ozuguz Pinar - - 2013
Abstract Background: Although hyperseborrhea, follicular hyperkeratinization, Propionibacterium acnes colonization and inflammation are found to be responsible in the pathogenesis of acne, the exact mechanisms are unknown. Vitamin A and E are basic antioxidants vital for health. Zinc is also an essential element for human. But these parameters of the effects ...
Lingen Christiaan van - - 2013
Reports of adverse reactions to metal particle debris with metal-on-metal (MoM) hip arthroplasty have increased recently. Apart from the formation of pseudotumours and higher revision rates, another major cause for concern are the systemic effects of metal ions. Several effects of elevated systemic cobalt ions have been reported (e.g. myocardial ...
da Silva R - - 2013
BACKGROUND: Ataxia-telangiectasia (A-T) is a rare and degenerative disease that leads to varying degrees of immunodeficiency, oxidative stress, and malnutrition. Vitamin A and zinc are essential for immune function and antioxidant defence. OBJECTIVE: To compare levels of retinol, beta carotene, and zinc in patients with ataxia-telangiectasia and healthy controls. METHODS: ...
Younes-Mhenni S - - 2013
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder. The etiology of this disease is still not fully clear, but free radicals have been proposed to cause neuronal injury. Metals play a key role in the intracellular oxidative balance. However their implication in the degeneration process remains unknown. aim: To ...
Le Duff Michel J - - 2013
BACKGROUND: Impingement of the femoral neck with the acetabular component after metal-on-metal hip resurfacing arthroplasty (HRA) is a possible cause of edge loading and accelerated bearing wear. No attempt has been made to correlate radiographic impingement signs and blood metal ion levels. QUESTIONS/PURPOSES: We (1) compared serum cobalt (CoS) and ...
Verma Rajesh - - 2013
BACKGROUND: Vitamin B12 deficiency is a well recognized cause of posterolateral myelopathy. In Indian subcontinent, it may coexist with nutritional copper deficiency producing partial response of patients to B12 supplementation. Hence the study was planned to look for association of hypocupremia and B12 deficiency. METHODS: Twenty-three patients with posterolateral myelopathy ...
Zare Ahad - - 2013
Immunotherapy with paternal lymphocytes plays an important role in preventing recurrent spontaneous abortion (RSA) and is an effective treatment for it. This kind of treatment is performed as an immunotherapy method in several centers in the world. It attributes to the production of anti-paternal cytotoxic antibodies (APCAs) in women with ...
Ala Shahram - - 2013
Zinc and copper are important cofactors and modulators of many critical biological functions in many dermatological diseases including psoriasis. Studies must be performed in different societies to organize a governmental health organization nutritional program. Due to the lack of information related to these trace elements in Iranian psoriasis patients, the ...
Devrajani Bikha Ram - - 2013
To determine the serum zinc level in patients with pneumonia. The descriptive cross-sectional study was conducted at the Liaquat University Hospital, Hyderabad, Pakistan, from September 2008 to February 2009. All patients above 12 years of age and of either gender who had been diagnosed with pneumonia were further evaluated for ...
Okur Erdogan - - 2013
The aim of our study is to evaluate the status of selenium and zinc in nasal polyp tissues and to investigate the possible role of trace elements and antioxidants including superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in nasal polyps. In this study, the antioxidant enzyme and trace element levels ...
Erdoğan Elvan - - 2012
Zinc which is an essential element has very important effects on growth and immune system in patients with thalassemia major (TM). The effects of two oral iron chelator agents, desferrioxamine (DFO) and deferiprone (DFP), on zinc levels were investigated in previous studies and they were found to cause zinc deficiency. ...
Seven Mehmet - - 2012
PURPOSE: The accumulation of free radicals may lead to seizures and increase the risk of their recurrence. Glutathione peroxidase and superoxide dismutase are 2 major enzymes that are involved in antioxidative defense mechanisms. Selenium (Se), zinc (Zn), and copper (Cu) are important trace elements that participate in the structure of ...
Yonova D - - 2012
Background and aim: The physiological mechanisms regulating zinc homeostasis in humans have been elucidated and described, but the knowledge of zinc status and zinc distribution in the tissues and in the different biological compartments of patients with conservatively treated chronic renal failure (CRF) and on peritoneal dialysis is still insufficient. ...
Hon Kam Lun - - 2012
Due to increasing worldwide water pollution, fish might be a source of excessive zinc, mercury, arsenic or manganese intake. The aim of this study was to evaluate if fish atopy/sensitization and fish consumption behavior are associated with eczema severity and blood levels of the 4 heavy metals.One-hundred and nineteen patients ...
Bonnet Cecilia - - 2012
Spinocerebellar ataxia type 3 (SCA3) can be present with a combination of cerebellar, neuropathic, pyramidal, or extrapyramidal symptoms. Tremor is a classical but not frequent manifestation of SCA3 and there is a lack of detailed knowledge regarding its origin. To study the clinical and electrophysiological characteristics of tremor in SCA3 ...
Jax Steven A SA Moss Rehabilitation Research Institute, Elkins Park, PA 19027, USA. - - 2013
We report data from two left hemisphere stroke patients with moderate-to-severe ideomotor apraxia who exhibited deficits in positioning their hands to use 'conflict' objects (objects grasped and used with different hand postures) relative to controls and patients with mild apraxia. These novel data support the claim that actions to common ...
Herrera Elena - - 2012
Growing evidence supports the notion that the same brain areas involved in planning and execution of movements are also involved in verb processing. Recent studies have pointed out the existence of verb impairment in patients with Parkinson's disease (PD), a neurodegenerative disorder typically characterized by motor disturbance related to dopamine ...
Gentsch Antje - - 2012
BACKGROUND: Patients with obsessive-compulsive disorder (OCD) often lack the experience of action completion and have altered feelings of agency. This might depend on the integrity of predictions of action outcomes generated by forward models of the motor system. Such motor predictions are critical for inhibitory gating of actions and their ...
Peixoto-Santos José Eduardo - - 2012
In the central nervous system, zinc is released along with glutamate during neurotransmission and, in excess, can promote neuronal death. Experimental studies have shown that metallothioneins I/II (MT-I/II), which chelate free zinc, can affect seizures and reduce neuronal death after status epilepticus. Our aim was to evaluate the expression of ...
dos Santos-Valente E Calheiro - - 2012
Patients with common variable immunodeficiency (CVID) present with low antibody levels, impaired lymphocyte function, and chronic inflammation. Vitamin A and zinc are essential components of the immune system and can be redistributed in the body as a result of inflammation. To compare levels of retinol, beta-carotene, and zinc in patients ...
Lee Jong Bin - - 2011
OBJECTIVE:: To determine whether cochlear hydrops analysis masking procedure (CHAMP) has diagnostic value in patients with definite Ménière's disease (MD) comparing the diagnostic validity index of CHAMP with those of electrocochleography (ECoG). STUDY DESIGN:: A prospective study. SETTING:: Tertiary referral center. PATIENTS:: One hundred eight patients were classified into 3 ...
Aydin O - - 2011
BACKGROUND: Asthma symptoms can be triggered by a variety of factors commonly referred to as "triggers". Some of these factors can also induce severe asthma exacerbations. Thus, it can be assumed that actions taken against such triggers may prevent the progression of the disease. However, limited data exist on the ...
Hakkarainen Elina - - 2011
The study investigated stimulus evaluation time, event preparation, and motor action planning of patients with mild spastic cerebral palsy and a peer control group in the age range of 9 to 18 years. To this end, participants were carrying out a stimulus recognition task. Findings indicated an overall slowness and ...
Lin Cindy Shin-Yi - - 2011
To investigate the immediate and longitudinal mechanisms of action of intravenous immunoglobulin (IVIg) on axonal function in chronic inflammatory demyelinating polyneuropathy (CIDP). Prospective single-center study. Hospitals and outpatient clinics. Clinical and functional assessment, nerve conduction studies, and 526 motor excitability studies were undertaken in 27 patients, matched before and immediately ...
Allain Philippe - - 2011
The aim of the present study was to examine the syntactic and semantic dimensions of script representation in patients with structural damage within the cerebral cortex following a severe traumatic brain injury (TBI). Forty TBI patients and 38 healthy control subjects (HC) were asked to sort cards describing actions belonging ...
Choi Kee-Joon - - 2011
Aims Patients with Brugada syndrome (BS) often experience atrial fibrillation (AF) and atrial vulnerability, as measured by increased atrial conduction time. To date, however, dispersion of atrial repolarization has not been reported in these patients. Methods and results Monophasic action potentials (MAPs) recorded from four sites of the right atrium ...
Kim Deog Kyeom DK Channing Laboratory, Brigham and Women's Hospital, Boston, MA 02115, - - 2011
Severe hypoxemia is a major complication of chronic obstructive pulmonary disease (COPD). Long-term oxygen therapy is beneficial in hypoxemic COPD patients. However, the clinical and radiographic predictors of hypoxemia and the use of oxygen therapy are not well described. This study aimed to find the correlates of resting hypoxemia and ...
Toumanidis Savvas T H - - 2011
It has been suggested that control of GH and IGF excess can arrest the progression of cardiovascular abnormalities and normalize cardiac performance. The aim of the present study was to investigate the reversibility of acromegalic cardiomyopathy in patients with active and inactive disease and to evaluate the effect of the ...
Ciccone Marco Matteo - - 2011
BACKGROUND: The obstructive sleep apnoea syndrome (OSAS) is a common airways disease which often involves cardiovascular structures, causing vessel inflammation as well as hypoxia, induced by difficulties in the passage of air through the upper airways. Aim of our research is to evaluate the effects of Continuous Positive Airway Pressure ...
Brookhart M Alan - - 2011
Hemodialysis patients who live at high altitude use less exogenous erythropoietin but achieve higher hematocrit levels than those living at a lower altitude. The authors hypothesized that the effect of altitude would be strongest in hemodialysis patients with poor anemia treatment response. To explore this hypothesis, they studied anemia-related outcomes ...
Asaad Bassem O - - 2011
The principal benefits of mechanical ventilation during respiratory failure are improved gas exchange and decreased work of breathing. (1) We present a case of severe postoperative hypercarbia in a patient with severe obstructive pulmonary disease. In spite of maximal ventilation, bronchodilator therapy, sedation and paralysis, the patient continued to demonstrate ...
Johnston Ce - - 2011
Study Design. Clinical study correlating preoperative pulmonary function tests (PFTs) to radiographic measures of thoracic deformity severity in adolescent idiopathic scoliosis (AIS) patients.Objective. To determine 1) the incidence of clinically relevant (<65% predicted value) pulmonary impairment in AIS patients; 2) if patients with more severe deformity have greater impairment of ...
Cerasola Giovanni - - 2011
Introduction: Cardiovascular diseases are highly prevalent in patients with chronic kidney disease (CKD), and represent the major hazard for mortality in this population. Anomalies of left ventricular (LV) structure and function are very frequent too among CKD patients, and show a negative impact on cardiovascular prognosis. Methods: We searched PubMed ...
Boelen Danielle H E - - 2011
Objective: The authors investigated whether patients with brain injury suffering from dysexecutive symptoms had difficulties with script generation. Method: Forty-eight patients with brain injury of various etiology with complaints of executive dysfunctioning and deficient scores on executive tests were included in this study. They were compared with 99 healthy control ...
Akçaboy Erkan Yavuz - - 2011
We present the case of an 86-year-old patient with severe chronic obstructive pulmonary disease undergoing modified radical mastectomy with axillary dissection by thoracic paravertebral block (PVB). Use of thoracic PVB provided hemodynamic and respiratory stability, excellent unilateral anesthesia and high patient satisfaction.
Bolasco Piergiorgio - - 2011
Vascular calcifications produce a high impact on morbidity and mortality rates in patients affected by chronic kidney disease and mineral bone disorder (CKD-MBD). Effects are manifested from the more advanced stages of CKD (stages 3-4), particularly in patients undergoing dialysis (CKD5D). In recent years, a large number of therapeutic options ...
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