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Diab Sehriban S From the Department of Medicine, McMaster University, Hamilton, Ontario; Department of Medicine, McGill University; Division of Rheumatology, Lady Davis Institute, Jewish General Hospital, Montréal, Quebec; Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. Funded in part by Canadian Institutes of Health Research (FRN 83518), the Scleroderma Society of Canada and its provincial chapters, Scleroderma Society of Ontario, Sclérodermie Québec, Cure Scleroderma Foundation, Fonds de la recherche en santé du Québec, the Canadian Arthritis Network, and the Lady Davis Institute of Medical Research of the Jewish General Hospital, Montreal, Québec. Autoantibody diagnostic kits were a gift of INOVA Diagnostics Inc., Dr. Fooke Laboratorien GmbH, Euroimmun, and Mikrogen GmbH. The Canadian Scleroderma Research Group has also received educational grants from Pfizer and Actelion pharmaceuticals. Dr. Hudson is funded by the Fonds de la recherche en santé du Québec. S. Diab, MD; N. Dostrovsky, MD; N. Khalidi, MD, Department of Medicine, McMaster University; M. Hudson, MD, MPH; Department of Medicine, McGill University, Division of Rheumatology, Lady Davis Institute, Jewish General Hospital; S. Tatibouet, MSc, Lady Davis Institute, Jewish General Hospital; M.J. Fritzler, PhD, MD, Faculty of Medicine, University of Calgary; M. Baron, MD, Department of Medicine, McGill University, Division of Rheumatology, Jewish General Hospital. Address correspondence to Dr. M. Hudson, Jewish General Hospital, Room A-725, 3755 Côte Sainte-Catherine Road, Montreal, Quebec H3T 1E2, Canada. E-mail: marie.hudson@mcgill.ca. Accepted for publication July 24, - - 2014
To describe the clinical and serological features of systemic sclerosis sine scleroderma (ssSSc) in a multicentered SSc cohort. Data from 1417 subjects in the Canadian Scleroderma Research Group registry were extracted to identify subjects with ssSSc, defined as SSc diagnosed by an expert rheumatologist, but without any sclerodactyly or skin ...
Kim C H CH Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Konkuk University School of - - 2014
To describe vertical and horizontal components of head-shaking nystagmus (HSN) in various vestibular disorders. Retrospective case review. Tertiary care academic referral center. HSN was assessed in 66 vestibular neuritis (VN) patients at acute (<7 days) and follow-up (2 months), and 65 Meniere's disease (MD) and 76 migrainous vertigo (MV) in ...
Shenoy Niraj N Albert Einstein College of Medicine, Bronx, NY, United - - 2014
Myelodysplastic syndromes (MDS) are a group of heterogeneous clonal bone marrow disorders characterized by ineffective hematopoiesis, peripheral blood cytopenias, and potential for malignant transformation. Lower / intermediate risk MDS are associated with longer survival and high RBC transfusion requirements resulting in secondary iron overload. Recent data suggest that markers of ...
Grosse Gerrit M - - 2014
The chemokine fractalkine (CX3CL1, FKN) is involved in neural-microglial interactions and is regarded as neuroprotective according to several in vivo studies of inflammatory and degenerative states of the brain. Recently, an association with outcome in human ischemic stroke has been proposed. In this study, we aimed to investigate the temporal ...
Park Jonas J-H JJ Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Aachen, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany, - - 2014
Temporal bone abnormalities such as hypoplasia of the vestibular aqueduct or hypopneumatization of the mastoid have been described in Meniere's disease (MD). Jugular bulb abnormalities (JBA) are one of the most common temporal bone abnormalities. The aim of this study was to evaluate the frequency of JBA in MD. Radiological ...
Hermann Andreas - - 2014
To validate physical activity estimates by the Sensewear Pro3 activity monitor compared with indirect calorimetry during simulated free living in patients diagnosed with osteoarthritis of the hip pre or post total hip arthroplasty. Twenty patients diagnosed with hip osteoarthritis (10 pre- and 10 post total hip arthroplasty; 40% female; age: ...
McRackan Theodore Richardson TR *Department of Otolaryngology-Head and Neck Surgery, and †Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, - - 2014
A significant portion of the Ménière's disease (MD) population will ultimately have severe-to-profound hearing loss in their affected ear. When this occurs bilaterally or when a patient has poor hearing in the contralateral ear, these patients may meet criteria for cochlear implantation (CI). Here, we describe our institution's CI outcomes ...
Tutaj Marcin M Dept. of Neurology, Jagiellonian University Medical College, Cracow, Poland. Electronic address: - - 2014
To assess dynamic cerebral autoregulation (CA) in patients with acute ischaemic stroke of undetermined aetiology, within 72h of stroke onset. In 6 patients with ischaemic stroke of undetermined aetiology (aged 66±9 years, National Institutes of Health Stroke Scale [NIHSS] score on admission: 4.0, range: 4-11), selected based on screening of ...
Kim Hyungguen H Department of Rehabilitation Therapy, Graduate School of Hallym University, Republic of - - 2014
[Purpose] The purpose of this study was to assess the effect of horseback riding simulation machine training on trunk balance and gait of patients with chronic stroke. [Subjects and Methods] The subjects were 20 patients hospitalized for treatment after being diagnosed with stroke. Horseback riding simulation training was provided for ...
Horn Folkert K FK Department of Ophthalmology, Friedrich-Alexander University Erlangen-Nuremberg, Schwabachanlage 6, Erlangen, 91054, - - 2013
Purpose: To compare the results of Flicker Defined Form (FDF)-perimetry with standard automated perimetry (SAP) and retinal nerve-fiber-layer (RNFL) thickness measurements using spectral domain OCT. Methods: 64 healthy subjects, 45 ocular hypertensive patients, and 97 'early' open-angle glaucoma (OAG) patients participated in this study. Definition of glaucoma was exclusively based ...
O'Donnell C R CR Department of Pulmonary, Critical Care and Sleep Medicine, Harvard Medical School, Boston, MA, USA. Electronic address: - - 2013
To determine the range of tracheal collapse at end-expiration among chronic obstructive pulmonary disease (COPD) patients and to compare the extent of tracheal collapse between static end-expiratory and dynamic forced-expiratory multidetector-row computed tomography (MDCT). After institutional review board approval and obtaining informed consent, 67 patients meeting the National Heart, Lung, ...
Belenguer-Prieto Rafael R Rheumatology Department, Hospital 9 de Octubre, Valencia, Spain. - - 2013
To characterise patients diagnosed with fibromyalgia (FM) who present a clinical profile suggestive of simulation. Observational case-control study of 218 patients who met the classification criteria for FM. The profile supporting simulation was based on the proposed criteria for evaluating disability related to the simulation of pain. Compared with controls ...
Attanà Paola - - 2013
The aim of the present investigation is to evaluate whether basal lactate values and its dynamic changes played a prognostic role in cardiac arrest (CA) patients supported by venous-arterial extracorporeal membrane oxygenation (VA-ECMO). We enrolled 22 consecutive patients submitted to VA-ECMO for refractory CA. Lactate was measured on Intensive Cardiac ...
Hong Hye Ran - - 2013
Abstract Conclusion: Our findings suggest that migrainous vertigo (MV) has a substantial vestibulo-spinal abnormality that can be uncovered by posturography. Patients with MV also showed a difficulty in using multisystem information, especially somatosensory information. Caloric and sensory organization tests (SOTs) have complementary roles in assessing vestibulo-ocular and vestibulo-spinal function, particularly ...
Morishita Yuichiro - - 2013
Object The goal of this prospective study was to investigate somatosensory evoked potentials (SSEPs) during dynamic motion of the cervical spine and to evaluate the efficacy of analyzing dynamic SSEPs for predicting dynamic effects on the spinal cord in patients with cervical spondylotic myelopathy (CSM). Methods In total, 40 human ...
Mathis S - - 2013
Several groupshave published flow cytometry scores useful for the diagnosis or prognosis of myelodysplastic syndromes (MDS), mainly based on the detection of immunophenotypic abnormalities in the maturation of granulocytic/monocytic and lymphoid lineages. Because anemia is the most frequent symptom of early MDS, the aim of this study was to identify ...
Corrà Ugo - - 2013
BACKGROUND: Both heart failure (HF) treatment and management may distort or enhance the predictive accuracy of low peak oxygen consumption (pVO2≤10ml/kg/min), blurring the identification of specific patients in whom heart transplantation (HT) could make a clinical difference. The aim of this study was to re-evaluate the prognostic significance of pVO2≤10ml/kg/min ...
Huang Ching-Hui - - 2013
BACKGROUND: Left ventricular (LV) dyssynchrony is associated with increased risk of all-cause mortality in patients with end-stage renal disease. Our aim was to determine the associations of LV dynamic dyssynchrony with peritoneal solute clearance in continuous ambulatory peritoneal dialysis (CAPD) patients. Our primary objective was to determine the association between ...
Tesón Marisa - - 2013
To evaluate symptoms, signs, and the levels of 16 tears inflammatory mediators of dry eye (DE) patients exposed to an environment simulating an in-flight air cabin in an environmental chamber. Twenty DE patients were exposed to controlled environment simulating an in-flight airplane cabin (simulated in-flight condition [SIC]) of 23°C, 5% ...
Bleyenheuft C - - 2013
OBJECTIVES: To evaluate the effect of ankle-foot orthosis on lower limbs kinematic segmental covariation (KSC) among stroke patients. METHODS: Ten chronic hemiparetic spastic stroke patients presenting with a lack of ankle dorsiflexion were assessed with instrumented gait analysis under three conditions: wearing a shoe, with a prefabricated ankle-foot orthosis (AFO), ...
Kern Wolfgang - - 2013
BACKGROUND: Within the myelodysplastic/myeloproliferative neoplasm (MDS/MPN) category of the WHO (2008), only chronic myelomonocytic leukemia was so far evaluated by multiparameter flow cytometry (MFC). METHODS: To investigate the potential of MFC for MDS/MPNs, unclassifiable (MDS/MPNu), and refractory anemia associated with ring sideroblasts and marked thrombocytosis (RARS-T), we studied 91 patients ...
Sarrafzadeh Asita - - 2013
The pathogenesis of delayed cerebral ischemia (DCI) is multifactorial and not completely elucidated. Our objective was to determine if episodes of spreading depolarization (SD) are reflected in compromised levels of extracellular glucose monitored by bedside microdialysis (MD) in aneurysmal subarachnoid hemorrhage (aSAH) patients. Patients with aSAH, prospectively included in the ...
Verbanck Sylvia - - 2012
We investigated the extent of convective ventilation heterogeneity contributing to the observed lung clearance index (LCI) values in adult CF, as the result of 2 simulated scenarios: (a) a fixed part of the lungs becoming increasingly less compliant, or, (b) an increasingly greater part of the lung being less compliant.In ...
Maller Jerome J - - 2012
Background: Many people with a traumatic brain injury (TBI), even mild to moderate, will develop major depression (MD). Recent studies of patients with MD suggest reduced fractional anisotropy (FA) in dorsolateral prefrontal cortex (DLPFC), temporal lobe tracts, midline, and capsule regions. Some of these pathways have also been found to ...
Halamek Josef - - 2012
The patients with the long QT syndrome type-1 (LQT-1) have an impaired adaptation of the QT interval to heart rate changes. Yet, the description of the dynamic QT-RR coupling in genotyped LQT-1 has never been thoroughly investigated. We propose a method to model the dynamic QT-RR coupling by defining a ...
Ritz Patrick - - 2012
Abstract Background: About 70% of the patients operated on for a gastric bypass (Roux-en-Y gastric bypass [RYGB]) suffer from dumping syndrome. In these patients, previous studies have demonstrated a high glycemic variability with hypoglycemia and with altered continuous glucose monitoring (CGM) profiles. The aim of this study was to evaluate ...
Subbarayan Sreevidya - - 2012
Objective: To report the utility of IGF-1 as a single biomarker for establishing the diagnosis of acromegaly and to examine the clinical and biochemical profile of patients with an elevated IGF-1 in whom a diagnosis of acromegaly could not be confirmed by means of the oral glucose tolerance test (OGTT).Methods: ...
Nurjono Milawaty - - 2012
AIMS: This study aims to examine and compare the predictive utility of blood pressure (BP), waist circumference (WC) and body mass index (BMI), and to determine optimal cut-off values in prediction of metabolic syndrome (MetS) in patients with chronic schizophrenia. METHODS: About 100 patients with chronic schizophrenia were recruited. BMI ...
Wong Chong H CH Faculty of Medicine, University of Sydney, Sydney, New South Wales, - - 2012
Fluorine-18-fluorodeoxyglucose-positron emission tomography (FDG-PET) hypometabolism has been used to localize the epileptogenic zone. However, glucose hypometabolism remote to the ictal focus is common and its relationship to surgical outcome has not been considered in many studies. We investigated the relationship between surgical outcome and FDG-PET hypometabolism topography in a large ...
Ju Gawon - - 2012
Background: Decreased cerebral glucose metabolism has been reported in patients with sleep apnea syndrome (SAS), but it has yet to be decided whether cerebral glucose metabolism in SAS can be altered by continuous positive airway pressure (CPAP) treatment. Objective: The aim of this study was to evaluate cerebral glucose metabolism ...
Mácsai Emília - - 2012
Skin autofluorescence (SAF) measurement is a simple, noninvasive method to assess tissue advanced glycation end products (AGE). In patients with end-stage renal disease and in those on hemodialysis AGE production is increased. Less is known about those treated with peritoneal dialysis (PD). In this study we tested if SAF is ...
Nazlig 220 L Ya 351 Ar - - 2012
Background/aims: Glycogenic acanthosis is described as benign thickening of the esophageal squamous epithelium of unknown etiology. Although its etiology is unknown, it has been reported that glycogenic acanthosis may be related to gastroesophageal reflux and hiatal hernia. The aim of the present study was to review the patients who were ...
Liggi Mauro - - 2012
BACKGROUND AND AIMS: The histological similarities seen in Wilson's disease (WD) and non-alcoholic steatohepatitis (NASH) led us to verify possible correlations between glucose and/or lipid and/or iron metabolism alterations and hepatic steatosis in WD patients. METHODS: Thirty-five WD patients (20 females, 15 males, mean age 40.1±5.4 years), and 44 NASH ...
Rimachi R - - 2012
In this prospective, observational study, we measured arterial lactate and pyruvate concentrations within the first four hours of shock and at four hour intervals during the first 24 hours in 26 patients with septic and 13 with cardiogenic shock. We also studied 10 intensive care unit patients with normal lactate ...
Theodoropoulou A - - 2012
Background: Weight loss is a characteristic finding of patients with Alzheimer's disease (AD). It seems that precedes cognitive impairment by some years, but the underlying causes are not fully understood. Ghrelin and leptin are involved in energy homeostasis, and may be implicated in weight losing observed in these patients. Objective: ...
Dharmasaroja Pornpatr A - - 2012
In Asia, there is limited information regarding symptomatic intracerebral hemorrhage (ICH) in patients treated with intravenous (iv) recombinant tissue plasminogen activator (rtPA). The aim of this study was to identify independent factors associated with symptomatic ICH following iv rtPA. The study included 192 patients with acute ischemic stroke who were ...
Rana S V - - 2012
Background and Aims: Validity of the lactulose breath test (LBT) to diagnose small intestinal bacterial overgrowth (SIBO) has been questioned. Therefore, a study was planned to compare LBT with glucose breath test (GBT) to diagnose SIBO in irritable bowel syndrome (IBS) patients and controls. Methods: 175 diarrhea-predominant IBS patients and ...
Kim Shin-Young - - 2012
In the literature, numerous trials using neuroimaging techniques have investigated brain function in patients with post-traumatic stress disorder (PTSD). However, the contrasting results showed that improvements, including in the study design, were required to reach consistent and convincing conclusions. This study evaluated the functional neuroimaging pattern of resting cerebral blood ...
Garcia-Rizo Clemente C Schizophrenia Program, Department of Psychiatry, Neuroscience Institute, Hospital Clinic, University of Barcelona, Barcelona, Spain. - - 2012
Newly diagnosed, antipsychotic-naïve patients with nonaffective psychosis appear to have increases in pro-inflammatory cytokines. Patients characterized by primary, enduring negative symptoms (deficit symptoms) differ from patients without such features with regard to course of illness, treatment response, risk factors and metabolic disturbances. We hypothesized that they would also differ on ...
Winbladh Anders - - 2012
Continuous inflow vascular occlusion during liver resections causes less severe ischemia and reperfusion injury (IRI) if it is preceded by ischemic preconditioning (IP) or if intermittent inflow occlusion is used during the resection. No previous clinical trial has studied the effects of adding IP to intermittent inflow occlusion. Consecutive patients ...
Cherneva Zheyna Vlaeva - - 2012
Background: The clinical significance of inflammatory cytokines as independent prognostic markers in patients with acute coronary syndrome (ACS) and hyperglycaemia remains uncertain. Aim: To determine the value of inflammatory biomarkers as independent prognostic indicators and their relation with hyperglycaemia in ACS patients. Methods: TNF-α and hsCRP were defined 48 h ...
Kazancio─člu Rumeyza - - 2012
Standard peritoneal equilibrium test (PET) is an implementation that requires hard work for peritoneal dialysis (PD) staff. We analysed the efficacy of the fast PET and compared its results with standard PET. Forty-nine patients on PD therapy were included in the study. For standard PET, glucose, urea and creatinine values ...
García-Compeán Diego - - 2012
To define the prevalence and clinical characteristics of glucose metabolism disorders (GMD) in patients with compensated liver cirrhosis (LC). Fasting plasma glucose (FPG) levels were measured to 130 patients with clinically stable LC. Oral glucose tolerance tests (OGTT) and fasting plasma insulin determinations were performed to patients with normal FPG. ...
Bernardo Ana Paula - - 2012
Reduced free water transport (FWT) through ultrasmall pores contributes to net ultrafiltration failure (UFF) and should be seen as a sign of more severe functional deterioration of the peritoneal membrane. The modified peritoneal equilibration test (PET), measuring the dip in dialysate Na concentration, estimates only FWT. Our aim was to ...
Shimizu Megumi - - 2012
The purpose of this study was investigate functional alteration in the brains of patients with hemifacial spasm using positron emission tomography (PET). We studied cerebral glucose metabolism using PET with (18) F-fluorodeoxyglucose in 13 patients with right lateral hemifacial spasm and 13 with left lateral hemifacial spasm. All patients underwent ...
Versteylen Mathijs O - - 2012
AIMS: Epicardial adipose tissue (EAT) volume has been associated with coronary artery disease (CAD). As diabetes mellitus type 2 (DM2) patients have higher EAT volumes, it has been suggested that EAT may play a role in promoting CAD in these patients. The aim of this study was to examine the ...
Roslin Mitchell S - - 2012
BACKGROUND: Symptoms secondary to dumping have been suggested to help patients refrain from simple carbohydrate ingestion after Roux-en-Y gastric bypass (RYGB). During follow-up examinations, we noted many patients with weight regain complaining of fatigue shortly after eating. Thus, we decided to study the glucose tolerance test (GTT) results in a ...
Frosini M - - 2012
Abstract Stroke is one of the most debilitating diseases and it is unfortunate that only a small percentage of patients can be treated with thrombolytic agents. Consequently, there is an urgent need of finding an alternative procedure for reoxygenating the so-called penumbra at the earliest time as possible for reducing ...
Fujishiro Hiroshige - - 2012
BACKGROUND: Although metabolic reduction in the primary visual cortex on [(18) F]-fluoro-d-glucose (FDG) positron emission tomographic (PET) scans is the hallmark of dementia with Lewy bodies (DLB) for differential diagnosis from Alzheimer's disease, the clinical significance of the metabolic pattern in patients without dementia remains unknown. The purpose of this ...
Meyer Gesine - - 2012
Hypoglycemia can be a symptom in patients with Addison's disease. The common regimen of replacement therapy with oral glucocorticoids results in unphysiological low cortisol levels in the early morning, the time of highest insulin sensitivity. Therefore patients with Addison's disease are at risk for unrecognized and potentially severe nocturnal hypoglycemia ...
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