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Results 501 - 550 of 718
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Matsumoto T - - 1993
To determine the mechanism of easy infectability of uremic patients, we studied the effect of sera from uremic patients who were undergoing chronic hemodialysis on the chemiluminescence (CL) response of polymorphonuclear leukocytes (PMN). The luminol-dependent CL response was examined following stimulation with phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (FMLP). The ...
Weisensee D - - 1993
Cardiovascular complications determine the prognosis of patients with chronic renal failure. The contribution of compounds retained during uremia to specific myocardial lesions is controversial. We investigated the contractility of spontaneously beating mouse cardiac myocytes in culture under perfusion with sera derived from patients on maintenance hemodialysis and test solutions containing ...
Dalal S - - 1992
Penile calcification was detected in 6 of 32 patients (19%) with end-stage renal disease (ESRD) using soft tissue x-ray techniques. Having been maintained on hemodialysis for a minimum of one year, all the affected patients showed clinical evidence of secondary hyperparathyroidism and calcification in the blood vessels of some other ...
- - 1992
We analyzed the dialysis prescription parameters for 4,532 randomly chosen incident Medicare patients who reached end-stage renal disease (ESRD) in 1986-87. Data were abstracted from the patient's record by the ESRD Networks. Dialysis prescription was assessed at one month following onset of ESRD. Eighty-four percent (3,823) of these patients were ...
Pegues D A - - 1992
Pyrogenic reactions (PR) are a well-recognized complication of hemodialysis and have been associated with dialyzer reuse, high-flux dialysis, and bicarbonate dialysate. However, the roles of bacteria and endotoxin in dialysate for producing PR are not well defined. To determine the effect of removing most bacteria and endotoxin from the dialysate ...
Bambauer R - - 1992
With a miniaturized plasmapheresis system consisting of a double head pump and balancing pump, extracorporeal detoxification treatments such as plasmapheresis, hemofiltration, and hemodialysis were carried out. In total 15 premature infants and newborns with Rherythroblastosis and hyperbilirubinemia were treated using this miniaturized system. The average birth weight of the 15 ...
Kar P M - - 1992
Several extracorporeal techniques have been used to remove N-acetylprocainamide (NAPA), the major metabolite of procainamide, in patients intoxicated with this substance. We report a patient with life-threatening NAPA intoxication who was rapidly and successfully treated with combined high-efficiency hemodialysis and charcoal hemoperfusion. The hemodialyzer and hemoperfusion cartridge were placed in ...
Coupland D B - - 1992
The authors report a patient with diffuse pyogenic pericarditis and focal myoendocarditis initially detected using In-111 WBC scintigraphy. The patient was in septic shock after hemodialysis for the treatment of chronic renal failure. This was preceded by clinical signs and symptoms of pericarditis thought to be viral in nature. Initial ...
Antonucci F - - 1992
Seven patients undergoing chronic hemodialysis presented a total of ten venous stenoses which were treated with self-expanding metallic vascular endoprostheses. Four lesions were central (brachiocephalic and subclavian vein). One acute occlusion could be successfully recanalized by PTA. Restenosis prompted seven secondary interventions. Four patients underwent a kidney transplantation between 5 ...
Kaplan B - - 1992
Hemodialysis-associated skeletal muscle cramps are generally ascribed to a reduction in plasma volume, but during this procedure, it is not known how volume contraction results in cramps. To elucidate this mechanism, we compared responses to one hour of 60 degrees head-up tilt in 8 patients who cramped during no more ...
Kooman J P - - 1992
A reduced venous compliance and/or inadequate venoconstriction could impair hemodynamics during hemodialysis. Therefore, compliance and reactivity of the peripheral venous system were assessed in hemodialysis patients and controls using strain gauge plethysmography. Reactivity of the venous system towards an efferent sympathetic stimulus was assessed using a cold pressor test. Results ...
Gallice P - - 1992
Erythrocyte thermogenesis was studied by flow microcalorimetry in 25 healthy subjects and 27 uremic patients. The heat production (HP) from cells in plasma, decrease in HP induced by ouabain (a specific sodium pump inhibitor) and index of rate response to ouabain action were measured. HP was higher in uremic patients ...
Stein G - - 1992
Postmortem examinations were carried out in 13 patients (6 males, 7 females, age 58 +/- 9 years) who had been on regular hemodialysis treatment for 10-90 months using disposable regenerated cellulose membrane dialyzers. The prevalence of beta 2-microglobulin (beta 2m)-derived AB-amyloid deposits in different sites was determined. At autopsy, specimens ...
Durakovic Z - - 1992
In this paper four patients are presented who had been poisoned by 2,4-dichlorophenoxyacetic acid (2,4-D). The first patient, aged 51 years, had attempted to commit suicide by taking orally 400 ml of a 40% solution of 2,4-D. He was admitted in a coma, 6.5 h after poisoning. Extracorporal hemodialysis was ...
Ozasa H - - 1992
Plasma levels of hyaluronic acid (HA) and acute-phase reactants were determined in chronic hemodialysis patients with or without carpal tunnel syndrome (CTS) and/or shoulder pain, which are characteristic symptoms of amyloid-associated osteoarthropathy. While levels of acute-phase reactants tended to be higher in the patients with CTS and/or shoulder pain than ...
Drinovec J - - 1992
Erythropoietin was applied subcutaneously to 49 patients, 41 have been treated by hemodialysis, 3 by continuous ambulatory peritoneal-dialysis, 5 had chronic progressive renal failure. Mean initial dose of erythropoietin was 139.4 U/kg/week and maintenance dose 115.9 U/kg/week. In 43% of patients serum ferritin was decreasing during treatment, and in 20% ...
Ståhle-Bäckdahl M - - 1992
Despite advances in dialysis treatment, pruritus remains a common and distressing manifestation of chronic renal failure. Two-thirds of patients on maintenance hemodialysis experience persistent itching, however, the etiology of this condition is unknown. Although pruritic patients have higher serum levels of parathyroid hormone (PTH) than nonpruritic patients, subsequent studies do ...
Carretta R - - 1992
Hypotension is a common problem in patients on hemodialysis. To further investigate this problem, the number of platelet alpha 2-adrenoceptors and the activity of lymphomonocyte beta 2-adrenoceptors were measured in 10 hemodialyzed patients with normal blood pressure and in 10 sex- and age-matched persistently hypotensive hemodialyzed patients. Density of alpha ...
Sunder-Plassmann G - - 1991
IL-1 activity is increased in hemodialysis patients and interest has recently been focused on IL-1 antagonism in various clinical settings. We studied the presence of anti-IL-1 alpha autoantibodies in sera from 49 hemodialysis patients, 159 kidney graft recipients and 89 chronic renal failure patients without renal replacement therapy. Within the ...
Yver L - - 1991
A right adrenal tumor was found incidentally by renal echography in a 25-year-old man, who had been on hemodialysis for 4 years. Inquiry and clinical examination suggested pheochromocytoma, which was confirmed by plasma catecholamine measurements. Subsequent adrenalectomy was uneventful. Although hypertension, headache, and diaphoresis are common symptoms in a dialyzed ...
Yang C S - - 1991
Acetate dialysate is currently the most widely used in hemodialysis. The adverse effect of acetate during hemodialysis is well known upon the cardiovascular system. However, hypersensitivity reactions related to acetate during dialysis therapy are rare. We report a patient who developed hypersensitivity reactions such as generalized skin itching, flushing, hypotension ...
Ezeamuzie I C - - 1991
The incidence and nature of pruritus induced by chloroquine and halofantrine were studied in 82 patients with acute malaria and in 40 healthy subjects, using a visual analogue scale for quantitating pruritus. Results showed that the proportion of patients with acute malaria manifesting itch to halofantrine was significantly lower than ...
Descombes E - - 1991
We report the case of a patient with terminal renal disease on chronic hemodialysis who developed acute thiamine deficiency as confirmed by erythrocyte transketolase determinations. The patient presented with a confusional state and severe memory disturbances, but other classical features of Wernicke's encephalopathy were absent. Almost all central nervous system ...
Reyes A - - 1991
OBJECTIVE: To assess acid-base derangements during sorbent regenerative hemodialysis in mechanically ventilated patients. DESIGN: Consecutive case series; prospective study. SETTING: An ICU in a university hospital. PATIENTS: Seven patients undergoing hemodialysis for acute renal failure who required mechanical ventilation for acute respiratory failure. INTERVENTIONS: Pulmonary and systemic hemodynamics, pH, and ...
Kaye M - - 1991
Three patients on long term hemodialysis were found to be hypophosphatemic. They were treated using a calcium-free dialysate to which phosphate was added to give a final concentration of 1 or 2 mmol/l. All corrected their low phosphates. Hypocalcemia developed in two patients when the calcium infusion rate was 15 ...
Harasawa H - - 1991
Fifty-eight examples of upper extremity venography in 40 patients undergoing or about to undergo hemodialysis and 18 normal subjects were evaluated. In the normal subjects, tools and conditions of venography were investigated. It was considered necessary to maintain 30 degrees flexion of the cubital joint and supination of the antebrachium ...
Arora N - - 1991
Purtscher's-like retinopathy as a cause of sudden blindness in hemodialysis patients is not widely known. This is believed to occur secondary to leukoembolization to retinal arterioles following complement activation. We describe a patient who developed sudden but reversible loss of vision on hemodialysis associated with varying reversible neurological signs and ...
Sabater J - - 1991
In order to ascertain whether there are abnormalities of nonenzymatic glycosylation in uremia, the levels of nonenzymatically glycosylated hemoglobin (GHb), and total plasmatic glycosylated proteins (PGP) were studied using the thiobarbituric acid (TBA) method, a procedure not interfered with by carbamylation. Total hemoglobin A1 (HbA1) and the A1c fraction were ...
Nakahama H - - 1991
The pharmacokinetics of denopamine on a hemodialysis day and on an interdialysis day was evaluated in 11 hemodialysis patients. Tmax was the only pharmacokinetical parameter that differed significantly between healthy volunteers and hemodialysis patients. It is suggested that denopamine can be administered to hemodialysis both on hemodialysis days and on ...
Kawano Y - - 1991
The ability of blood mononuclear cells (MNC) to produce burst promoting activity (BPA) was evaluated in 31 patients with chronic renal failure. The BPA of cells from uremic patients, with or without hemodialysis, was consistently lower than that of 17 normal donors (mean 64%, P less than 0.01). Coculture of ...
Garcia-Maldonado M - - 1991
Impaired cognitive function is part of an array of neurologic manifestations seen in patients with end stage renal disease. We investigated whether a difference exists in mental performance between patients on hemodialysis and on CAPD. The trial test A was administered in standardized fashion, and the time required to complete ...
Hayashi M - - 1990
Hair samples taken from a patient group comprising 28 long-term hemodialysis patients (14 males and 14 females) and a control group comprising the same number of normal humans with the same age, sex, residence region, working region and sampling timing as the patient group were analyzed for 22 elements. These ...
Zemel G - - 1990
Directional atherectomy has proved useful in the treatment of peripheral vascular occlusive disease, and the authors have begun using this modality in the treatment of patients with failing hemodialysis access fistulas. The authors describe their initial experience with 13 patients in whom directional atherectomy was used to treat stenotic hemodialysis ...
Voerman H J - - 1990
Intermittent hemodialysis in critically ill patients is often accompanied by circulatory instability and hypotension. This may hamper the removal of fluid. Therefore, slow, continuous arterial-venous hemodiafiltration (CAVHD), using the patient's arterial-venous pressure difference, was developed. In 17 critically ill patients with acute renal failure, CAVHD was initiated. Most patients (n ...
Saito Y - - 1990
Pulse wave velocity (PWV) is known to reflect the stiffness of the aorta, one of the major features of atherosclerosis. To clarify the severity and progression mechanism of atherosclerosis in hemodialysis patients and the preventive effect of nifedipine, PWV was annually measured for 2 years, and the change of PWV ...
Docci D - - 1990
The incidence of elevated acute phase reactants, measured by nephelometry, was examined in 69 otherwise uncomplicated hemodialysis patients in comparison with 30 healthy subjects. Increased C-reactive protein was found in 40.6% of the patients (p less than 0.001 vs controls) and the degree of increase was correlated with the duration ...
Eisenberg B - - 1990
We present a case of a 58-yr-old male to illustrate the scintigraphic, roentgenographic, clinical, and pathologic features of periarticular tumoral calcinosis that occurred in a hemodialysis patient. Soft-tissue calcifications developed 3 yr after onset of hemodialysis, became progressively larger during the ensuing five years, and culminated in voluntary withdrawal from ...
Sherman R A - - 1990
Decreased left ventricular compliance because of hypertrophy or fibrosis may contribute to hypotension during hemodialysis. While calcium channel blockade may reduce intradialytic hypotension in patients with left ventricular hypertrophy and refractory pulmonary congestion, it is unknown whether such an effect might be seen in unselected hemodialysis patients. Verapamil (40 mg) ...
Ruiz P - - 1990
Infection is a frequent complication in patients undergoing hemodialysis for end-stage renal disease and is the primary cause of mortality among such patients. Macrophages are important in host defense against infection largely because their Fc gamma receptors recognize antibody-coated bacteria. We therefore studied macrophage Fc gamma-receptor function in vivo and ...
Fonseca V - - 1990
We describe two patients on hemodialysis who developed staphylococcal splenic abscesses. Both patients previously had staphylococcal septicemia secondary to infection at the dialysis access site. We postulate that access-site infections may predispose hemodialysis patients to splenic abscess, and that these patients should be investigated for a splenic abscess if they ...
Bamford C R - - 1990
Two patients with similar clinical features are presented: both patients had chronic renal failure, on hemodialysis for many years but recently begun on a high-flux dialyzer; both had been receiving a carbidopa/levodopa preparation; and both had the onset of hallucinosis and recurrent seizures, which were refractory to anticonvulsants. The first ...
Grunze M - - 1990
Correction of the anemia that is common among chronic hemodialysis patients by treatment with human recombinant erythropoietin (rHuEPO), even if incomplete, improves physical performance of patients. Oxygen uptake and physical work capacity at maximal work loads and at the anaerobic threshold increase by approximately 20%. Analysis of underlying mechanisms by ...
Taniguchi T - - 1990
We examined endotoxins and limulus amebocyte lysate-reactive material (LAL-RM) in serum from 87 patients on hemodialysis, using the conventional chromogenic limulus test (CCLT) and a new specific endotoxin assay with factor G-free LAL (endotoxin-specific test: EST). All patients with regenerated cellulose dialyzers had increased CCLT values, whereas the EST values ...
Tsukamoto Y - - 1990
Vanadium (V) has been reported to inhibit a number of enzyme activities such as those of Na(+)-K(+)-ATPase. The main excretory pathway of this element is via the kidney. These facts led us to study the V distribution in uremic patients. As a result, hemodialysis patients at our dialysis center exhibited ...
Baker L R - - 1989
Cognitive function was assessed, and unenhanced CT head scans were carried out in 44 patients with renal failure. Thirteen had been on regular hemodialysis for 5 years or more (long-term hemodialysis group, LTHD), 12 had received hemodialysis for less than 5 years (short-term hemodialysis, STHD), 9 were on continuous ambulatory ...
Maeda Y - - 1989
Hypogonadism in male hemodialysis patients has been previously reported. However, its precise pathogenesis has not yet been clarified. Mepitiostane and nandrolone decanoate are anabolic steroids prescribed for uremic anemia, and those may possibly exacerbate uremic gonadal damage. We studied the influences of these steroids on male gonadal function. Seventy-six hemodialysis ...
Oster J R - - 1989
To compare the effect of maintenance bicarbonate hemodialysis on the serum anion gap (AG) and the serum HCO3, the authors retrospectively evaluated the data of 28 patients using the first-of-the-month blood chemistries. Data were available for at least 9 of the previous 12 months in each case. For the entire ...
Erbelding E - - 1989
Despite the technical advances made during the last several years, chronic dialysis still is plagued by continuing problems. Intermittent volume overload is one of the most common. The radiologic evidence of pulmonary edema can be confusing in the end-stage renal disease population. The following case illustrates a hemodialysis patient with ...
Semer N B - - 1989
Patients with end-stage renal disease, undergoing hemodialysis, have been shown to have an increased prevalence of carpal tunnel syndrome. From mid-1981 through 1986, 21 patients undergoing hemodialysis were operated on for 33 cases of clinically diagnosed entrapment of the median and/or ulnar nerves, including 14 extremities with functioning vascular access. ...
Galen M - - 1989
To evaluate the ability to provide short hemodialysis (less than 9 hr per week) without the requirement for costly ultra-high efficiency dialyzers and ultrafiltration control delivery systems, 69 patients maintained on chronic hemodialysis were studied. Standard dialysis was delivered with bicarbonate dialysate, Baxter CF 1211 dialyzers, QB = 300 ml/min, ...
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