Search Results
Results 301 - 350 of 1729
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Porta Mauro - - 2008
Gilles de la Tourette's syndrome (Tourette's syndrome; TS) is an inherited tic disorder commonly associated with other neurobehavioural conditions such as attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). While the clinical presentation of TS and other features of this disorder have been well characterized, the genetic and neurobiological basis ...
Verrotti Alberto - - 2008
The aim of this study was to evaluate the efficacy and tolerability of levetiracetam (LEV) monotherapy in juvenile myoclonic epilepsy (JME). The study group consisted of 32 patients with epilepsy (20 males, 12 females) with a mean age of 13 years 3 months (SD 7y 11mo) at seizure onset. LEV ...
Jabs Ronald - - 2008
Currently available anticonvulsant drugs and complementary therapies are insufficient to control seizures in about a third of epileptic patients. Thus, there is an urgent need for new treatments that prevent the development of epilepsy and control it better in patients already afflicted with the disease. A prerequisite to reach this ...
De Reuck J - - 2008
BACKGROUND/AIM: Although most late-onset seizures (LS) appear within 2 years after stroke, some of them occur later and their characteristics are unknown. The aim of this study was to compare the characteristics of patients with very-late-onset seizures (VLS) to those with early-onset seizures (ES) and those with LS. PATIENTS: The ...
Duncan R - - 2008
Among a consecutive series of patients with psychogenic nonepileptic seizures (PNES), we compared patients with learning disability (LD) (n=25) with patients with no LD (n=263), with respect to demographic and clinical variables. A higher proportion of the LD group had epilepsy as well as PNES (P<0.001) (uncorrected P values are ...
González-Duarte Alejandra - - 2008
OBJECTIVE: To evaluate the frequency of and risk factors for epileptic seizures in patients with systemic lupus erythematosus (SLE) in a large cohort series. METHODS: One thousand two hundred patients with SLE were analyzed. The type and frequency of risk factors for seizures associated with SLE were studied and compared ...
Corry Jesse J - - 2008
INTRODUCTION: Status epilepticus (SE) can be refractory to conventional anticonvulsants, requiring anesthetic doses of medications to suppress seizures. This approach carries significant morbidity, is associated with a high fatality rate, and may not always control SE. Hypothermia has been shown to suppress epileptiform activity experimentally, but has not previously been ...
Simojoki Kaarlo - - 2008
BACKGROUND: In Finland, buprenorphine (Subutex) is the most abused opioid. In order to curb this problem, many treatment centres transferred ("forced transfer") their buprenorphine patients to the buprenorphine plus naloxone (Suboxone) combination product in late 2003. METHODS: Data from a retrospective study involving five different treatment centers, examining the effects ...
Richter Gresham T - - 2008
OBJECTIVE: To identify and describe the features of laryngomalacia (LM) in a cohort of older children, with the goal of providing an approach to diagnosis and management of these patients. Laryngomalacia is a common congenital disorder characterized by decreased laryngeal tone, supraglottic collapse, and stridor during inspiration and is rarely ...
Drane Daniel L DL Department of Neurology, University of Washington, Seattle, WA, United States; UW Regional Epilepsy Center, Harborview Medical Center, Seattle, WA, United States. - - 2008
Based upon Damasio's "convergence zone" model of semantic memory, we predicted that epilepsy surgical patients with anterior temporal lobe (TL) seizure onset would exhibit a pattern of category-specific naming and recognition deficits not observed in patients with seizures arising elsewhere. We assessed epilepsy patients with unilateral seizure onset of anterior ...
Peltola J - - 2008
OBJECTIVES: This aim of the study was to ascertain the importance of clinical parameters on the response to treatment in refractory epilepsy patients on levetiracetam (LEV). MATERIALS AND METHODS: We retrospectively evaluated medical records of 132 patients aged 17-78 years with refractory epilepsy (defined as a failure of at least ...
Tohyama Jun - - 2008
Numerous numbers of pre-, peri- and postnatal damages cause West syndrome in early infancy, however, etiology in many cases are not still elucidated despite intensive biochemical and neuroradiologic investigations. We described four patients having early onset epileptic encephalopathy with severe hypomyelination and reduction in cerebral white matter. The clinical symptoms ...
Dodrill Carl B - - 2008
Drane et al. (2006) has recently raised the possibility that patients with psychogenic nonepileptic seizures (PNES) may make poor effort in taking neuropsychological tests in comparison with patients with epilepsy (ES). Therefore, findings previously reported with PNES patients may be in error, especially with regard to tests of mental abilities. ...
Alfradique Isabel - - 2007
Juvenile myoclonus epilepsy (JME) is a common epileptic syndrome, the etiology of which is genetically determined. Its onset occurs from 6 through 22 years of age, and affected patients present with myoclonic jerks, often associated with generalized tonic-clonic seizures - the most common association - and absence seizures. JME is ...
Sekimoto Masanori - - 2007
Autonomic symptoms and signs rarely occur as isolated phenomena without impaired consciousness. Ictal nausea with vomiting is a rare clinical manifestation of seizures. Ictal vomiting is considered a localizing sign in patients with partial seizures of temporal origin. We encountered two patients with simple partial seizures that produced nausea with ...
Hovorka Jirí - - 2007
In our study, we evaluated 249 patients with refractory seizures using video-EEG monitoring. In this sample, we identified 56 (22.5%) patients with psychogenic non-epileptic seizures - PNES only. Spontaneous seizures were recorded in 49 (87%) patients with PNES. Suggestive seizure induction using intravenous saline placebo was successful in 77.1% of ...
Kawai Makoto - - 2007
Video-EEG monitoring is a standard tool to evaluate possible seizures. However, there are limited data available for the elderly population, and no data are available for the elderly veteran population. The records of 71 veterans ages 60 and older who underwent video-EEG monitoring at the Michael E. DeBakey Veterans Affairs ...
Fernández-Guarino Montse - - 2008
INTRODUCTION: Phakomatosis pigmentovascularis (PPV) is a rare syndrome characterized by the association of a vascular nevus with an extensive pigmentary nevus. OBJECTIVE: We sought to study and evaluate clinical findings in patients with PPV referred to the laser department of our hospital. METHODS: We revised the clinical findings of 15 ...
Khan, Wasif A.
Objective: Review the neurologic manifestations of shigellosis in children. Methodology: Eight hundred sixty-three consecutive patients with shigellosis, admitted to the treatment centre of ICDDR.B during a one-year period, were prospectively studied. Patients were divided into four groups based on history and findings of physical examinations: conscious; unconscious; seizure witnessed in ...
Sonneville Romain - - 2008
OBJECTIVE: Because acute disseminated encephalomyelitis (ADEM) is a rare disease in adults admitted to the intensive care unit (ICU), we describe its characteristics and patient outcomes. DESIGN AND SETTING: A retrospective (2000-2006), observational, multicenter study was conducted in seven medical ICUs. Clinical, biological and neuroimaging features of patients diagnosed with ...
Villanueva Vicente - - 2007
BACKGROUND: Despite the correct use of antiepileptic drugs, control of seizures is not possible in 20% to 30% of people with epilepsy. This group of patients is considered to suffer from drug-resistant epilepsy, a clinical situation that can be caused by certain syndromes in which surgery can be used to ...
Guney Y - - 2007
INTRODUCTION: The purpose of this study is to report the clinical course and outcome in 7 patients with aggressive fibromatosis. MATERIAL AND METHODS: Between the years 2000 and 2003, 7 patients who were treated with combined modalities were evaluated retrospectively. Patients' demographic information, including age and gender, tumour characteristics, surgical ...
Roe Richard H - - 2007
OBJECTIVE: To describe a patient with oculoleptomeningeal amyloidosis associated with infiltration of the vitreous, elevated intraocular pressures (IOPs), and seizures caused by a TTR Val30Gly mutation in the transthyretin gene. DESIGN: Interventional clinicopathologic report. PARTICIPANT: A 44-year-old man with refractory bilateral intermediate uveitis, elevated IOPs, and seizures. INTERVENTION: The patient ...
Badiou Stéphanie - - 2008
The aim of our study was to investigate the effects of carbamazepine (CBZ) and oxcarbazepine (OXCBZ) on aminothiol levels, including homocysteine (Hcy), cysteine, and cysteinylglycine, in chronically treated patients. Epileptic patients receiving CBZ or OXCBZ were recruited as part of routine clinical practice. Demographic data and concomitant medications were recorded ...
Peltola Jukka J Department of Neurology and Rehabilitation, Tampere University Hospital, P.O. Box 2000, 33521 Tampere, Finland. - - 2008
We analyzed the effect of combination therapy on seizure frequency in all adult patients (N=193) with focal epilepsy followed at a single institution in a cross-sectional study. One hundred and thirty-five patients were on two AEDs, of them, 37 (27%) were seizure-free, 50 patients were on three AEDs including 5 ...
Bauer J - - 2008
Analysis of factors influencing seizure outcome in antiepileptic drug treatment of epilepsy. Retrospective analysis of 500 patients with complete seizure control and 321 patients with refractory epilepsy (mean ages 33.3 and 32.1 years respectively). The seizure-free group consisted of 377 patients with symptomatic/cryptogenic epilepsy (SCE; mean seizure control 45 months) ...
Suenaga Naoko - - 2008
Prolonged febrile seizures may be followed by acute encephalopathy with neurological sequelae. To investigate the function of the blood-brain-barrier (BBB) in acute encephalopathy following prolonged febrile seizures with neurological sequelae (AEPFS), the concentrations of serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitors of metalloproteinases 1 (TIMP-1) were measured by ELISA in ...
Park Sung-Pa - - 2008
This study was a prospective, randomized, open-label investigation of the long-term effects of zonisamide (ZNS) monotherapy on cognition and mood of patients with epilepsy. Forty-three patients with epilepsy received ZNS, with final dose groups of 100, 200, 300, and 400mg/day. Cognitive and mood tests were done twice, at baseline and ...
Caicoya Anne G - - 2007
PURPOSE: Occipital lobe epilepsy is uncommon in epilepsy surgery series and often difficult to assess due to rapid seizure propagation, misleading seizure semiology and confounding interictal epileptiform activity. Ictal recordings with surface electrodes may not define properly the seizure onset zone in surgical evaluation for intractable occipital epilepsy. Specially in ...
Friedman David E - - 2008
PURPOSE: Prolonged electroencephalographic monitoring has facilitated the detection of nonconvulsive seizures. Compressed displays of EEG frequency spectra (such as compressed spectral array, CSA) can facilitate interpretation of continuous EEG by allowing the reader to observe on a single screen patterns evolving over many minutes or hours. METHODS: Patients were identified ...
Andrade R M - - 2008
To examine the predictors of time-to-seizure occurrence and their impact on damage accrual and mortality in LUMINA, a multiethnic (Hispanic, African American and Caucasian) cohort of patients with systemic lupus erythematosus. Seizures were defined as per the American College of Rheumatology (ARC) nomenclature and case definitions for neuropsychiatric lupus syndromes. ...
Pintaudi Maria - - 2007
PURPOSE: To describe resistant epileptic encephalopathies that significantly improved after an acute febrile episode (FE). METHODS: We reviewed the clinical history of patients with daily pharmacoresistant seizures referred to the Saint-Vincent de Paul Hospital in the last 5 years. Four patients experienced seizure arrest in relation with a febrile episode. ...
You Su Jeong - - 2008
PURPOSE: To compare the efficacy of corpus callosotomy and vagus nerve stimulation (VNS) for long-term adjunctive therapy in children with Lennox-Gastaut syndrome (LGS). METHOD: Fourteen patients underwent a total corpus callosotomy and 10 patients received VNS implantation. The patients were monitored for more than 12 months after treatment, and seizure ...
Ali A - - 2007
A 74-year old man presented with recurrent attacks of altered sensorium, sometimes with abrupt falls, against the background of a long history of chronic obstructive airways disease and ischaemic heart disease. Investigations revealed evidence of significant cardiac conduction abnormalities and this led to the insertion of a permanent pacemaker. However, ...
Rasmussen Keith G - - 2007
Disorders of sodium balance can result in seizures. In electroconvulsive therapy (ECT) practice, it is customary to obtain electrolytes, including sodium, before treatment. A question that arises is whether the patient with mild disturbances of sodium can safely be treated with ECT or whether normalization of serum sodium is needed ...
Lossius M I - - 2007
The aim of this study was to assess cardiac autonomic control in patients with epilepsy before and after withdrawal of antiepileptic drugs (AEDs). The study was prospective, randomized and double blinded. Spectral analysis of heart rate variability (HRV) in 24 h ECG-registration before and after withdrawal of AEDs was used ...
Janik Piotr - - 2007
BACKGROUND AND PURPOSE: Gilles de la Tourette syndrome (TS) is characterized by the presence of multiple motor and vocal tics, as well as other neuropsychiatric disorders. The aim of the study was to evaluate the frequency of particular clinical symptoms in patients diagnosed with TS. MATERIAL AND METHODS: A hundred ...
Dunin-Wasowicz Dorota - - 2007
From 1 January 1995 to 31 December 2004, 22 patients (13 males, nine females; age range 2-12mo) with infantile spasms and cytomegalovirus (CMV) infection were treated with intravenous ganciclovir (GCV) and antiepileptic drugs. GCV was given for 3 to 12 weeks with a 1-month interval (one, two, or three courses). ...
Haseeb Ateeq A Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI 48201, - - 2007
We determined whether the primary motor hand area was most frequently located in the precentral gyrus in young patients with intractable focal seizures. Sixty-five patients with focal seizures aged between 5 months and 20 years who underwent a two-stage epilepsy surgery using chronic subdural-EEG monitoring were studied. Pairs of subdural ...
Widdess-Walsh P - - 2007
BACKGROUND: Patients with partial epilepsy may report multiple types of aura during their seizures. The significance of the occurrence of multiple auras in the same patient is not known. METHODS: The clinical and electrophysiologic characteristics of patients with more than one aura type (abdominal, auditory, autonomic, gustatory, olfactory, psychic, somatosensory, ...
Urrestarazu, Elena
Interictal fast oscillations between 100 and 500 Hz have been reported in signals recorded from implanted m<it>i</it>croelectrodes in epileptic patients and experimental rat models. Oscillations between 250 and 500 Hz, or fast ripples (FR), appeared related to the epileptic focus whereas ripples (80–200 Hz) were not. We report high-frequency oscillations recorded with intracranial ...
Fakhoury Toufic - - 2007
Many adults with epilepsy have breakthrough seizures despite treatment with antiepileptic drugs (AEDs), requiring them to have a rescue medication as part of a comprehensive treatment plan. We evaluated the effectiveness and tolerability of rectal diazepam in the treatment of breakthrough seizures in adult patients with epilepsy. We identified 50 ...
RAFIEI, SEYYED MOHAMMAD
The provocative effects of sleep deprivation (SD) on patients with seizure disorder and on the electroencephalogram (EEG) are well known.The purpose of the study was to test its routine use and usefulness in the pediatric and adolescent age group with, or suspect of having, seizure disorder, especially those presenting with ...
Zhao Yao - - 2007
BACKGROUND: Although patients with MCMs have increasingly been found in clinics, little has been focused on them. Thus, we intended to investigate these patients' clinical presentations, family history, radiological characters, and treatment strategy. METHODS: A retrospective review of the files and family investigations were conducted for 30 patients with MCMs. ...
Asche C V CV Outcomes Research Center, Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, UT 84108, USA. - - 2008
To quantify adverse events (AEs) associated with the use of metformin (MET), sulphonylureas (SUs) and thiazolidinediones (TZDs) in a usual care setting, and to assess the relationship of AEs to treatment patterns and glycaemic response in patients with type 2 diabetes. An electronic medical record database was used to identify ...
Yucus Chad J CJ Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City, Iowa, - - 2007
Anterior temporal lobectomy (ATL) is an effective surgical option for managing pharmacoresistant temporal lobe epilepsy. Many patients with left ATL develop postsurgical difficulties with proper name retrieval, although curiously, some patients have entirely intact proper naming following left ATL. Here, we tested the hypothesis that early age of seizure onset ...
Velasco Ana Luisa - - 2007
PURPOSE: Our aim was to evaluate the safety and efficacy of electrical stimulation of the hippocampus in a long-term follow-up study, as well as its impact on memory performance in the treatment of patients with refractory mesial temporal lobe epilepsy. METHODS: Nine patients were included. All had refractory partial complex ...
Hui Andrew C F - - 2007
OBJECTIVES: To investigate the proportion of Chinese patients with intractable seizures and the risk factors leading to refractory epilepsy. METHODS: Consecutive patients over 14 years of age attending a Neurology clinic were evaluated. Patients with epilepsy were classified into two groups according to their seizure control: refractory or seizure-free. Epilepsy ...
De Reuck J - - 2007
BACKGROUND: The relation between seizures and small subcortical infarcts is uncertain. The present retrospective study investigates whether differences are observed between patients with and without seizures following a lacunar stroke. PATIENTS AND METHODS: Thirty-seven patients with seizures and a prior history of a lacunar stroke were admitted to the Ghent ...
Spriet Isabel - - 2007
BACKGROUND: Valproate and meropenem are frequently used in the intensive care unit to treat seizures and serious infections, respectively. Several case reports have described a remarkable interaction between the drugs when administered concurrently. The interaction leads to a significant drop in plasma concentrations of valproate within 24 hours and relapse ...
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