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Results 101 - 150 of 1729
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Auvin Stéphane - - 2010
PURPOSE: Late-onset spasms (LOS) are epileptic spasms starting after the first year of life. Our aim was to assess the electroclinical features and the follow-up of the patients with this particular type of epileptic seizure. METHODS: We retrospectively included all patients with LOS confirmed by electroencephalography between 1989 and 2008. ...
Hoffmann Judith M JM Department of Epileptology, University of Bonn, 53105 Bonn, - - 2010
We aimed to assess the localizing value of the initial semiological element in temporal lobe epilepsy (TLE). Video-EEG-documented seizures of 97 adult TLE patients were studied in relation to seizure origin (left versus right; mesial versus extra-mesial). Strikingly, seizures with mesial onset started with very few ictal phenomena, while seizures ...
Stephen Linda J - - 2010
This audit examined outcomes for 203 patients prescribed zonisamide (ZNS) for various uncontrolled seizure types at a specialist outpatient service. Forty-two (20.7%) patients achieved 6 months of seizure freedom, and an additional 37 (18.2%) had a 50% seizure reduction for 6 months on a stable ZNS dose. Seizure freedom was ...
Thapa Amit A Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029, - - 2010
No large studies till date are available from India on post-traumatic seizures (PTS). This is a prospective observational study of 520 patients with traumatic brain injury (TBI) (July 2007-2008). Patients admitted after 24h of injury, with Glasgow coma scale (GCS)<or=4 were excluded. At a median follow-up of 386 days, 59 ...
Farooque Pue - - 2010
This report describes a 9-year-old child with status epilepticus and cat scratch disease. This patient's focal seizures and electroencephalographic changes persisted for 18 months after status epilepticus. This patient represents the third reported case of persistent focal seizures or electroencephalographic changes after status epilepticus secondary to cat scratch disease. This ...
Chiang I-Hui - - 2010
BACKGROUND: Seizures are important neurological complications of ischemic stroke. There is a need to further clarify the risk factors of seizures following ischemic stroke and predict those who will require treatment. METHODS: One hundred and forty-three (143) first-time ischemic stroke patients were enrolled in this one-year (2002) retrospective study. Prognostic ...
Martinove Mária - - 2010
Epilepsy is relatively frequent neurological condition. Its prevalence is assumed to be about 1%, and it would be interesting to see how many of these people have comorbid substance dependence disorder. The manifestation of epilepsy exhibits a seizure-like condition with typical neurological and psychical symptoms, which are induced by pathological ...
Standridge Shannon M - - 2010
The aim of this study was to determine the incidence and describe the factors influencing ictal cardiac arrhythmias in children with epilepsy. A 2-year review within a pediatric epilepsy monitoring unit revealed 2066 electrographically confirmed seizures in 139 patients. Demographic, seizure, and cardiac variables were collected for each patient. Fisher's ...
Lv X - - 2010
We report our experience in treating patients with seizures associated with brain arteriovenous malformations (AVM) without a clinical history of intracranial hemorrhage. Between 2001 and 2003, the neurovascular unit at Beijing Tiantan Hospital treated 109 patients with brain AVM endovascularly. Thirty patients (27.5%) experienced seizures before treatment. We studied the ...
Zeki Gokcil G Department of Neurology, Gulhane Military Medicine Faculty, Ankara, - - 2010
Hot water epilepsy (HWE) or bathing epilepsy is one of the reflex epilepsies induced by hot water pouring over the head, face, neck, or trunk during bathing. The aim of this study was to demonstrate the clinical and electroencephalographic features and the management alternatives of the patients with HWE. The ...
Bernardi Silvia - - 2010
PURPOSE: The aim of our study was to define the frequency of seizures in a population of outpatients attending a cognitive function clinic in Italy and to identify risk factors for seizures in patients with Alzheimer's disease. METHODS: In this retrospective study, we analyzed our clinical records to gather information ...
Chan Derrick - - 2010
The authors studied pediatric epilepsy and first afebrile seizure at presentation in Singapore. A total of 211 participants aged 1 month to 15 years with first presentation for afebrile seizures were recruited from November 2002 to May 2004; 108 with ≥2 prior afebrile seizures (newly diagnosed epilepsy) and 103 with ...
El Sabbagh Sandra - - 2010
PURPOSE: Epilepsy is a commonly reported but rarely described clinical hallmark of mitochondrial respiratory chain defects (RCDs) with encephalopathy. METHODS: From 1990-2006 we collected data about 56 children with RCD (single, n = 24 or multiple, n = 20 mitochondrial complex deficiencies; mtDNA mutation, n = 11; mtDNA depletion n ...
Seyal Masud - - 2010
PURPOSE: The rate of sudden unexpected death in epilepsy (SUDEP) approaches 9 per 1,000 patient-years in patients with refractory epilepsy. Respiratory causes are implicated in SUDEP. We reported that ictal hypoxemia occurs in one-third of seizures in localization-related epilepsy. We now report on respiratory changes in the ictal/postictal period including ...
An Dong-mei - - 2010
This article describes the clinical features of psychogenic nonepileptic seizures (PNES) in people in southwest China. Patients with a confirmed diagnosis of pure PNES by video/EEG monitoring were retrospectively reviewed. A total of 64 patients with PNES were included, 32 (50%) of whom were male. Twenty (31.3%) patients had previously ...
Saneto Russell P RP Division of Pediatric Neurology, Seattle Children's Hospital/University of Washington, Seattle, WA 98105, - - 2010
To review our clinical experience and determine if there are appropriate signs and symptoms to consider POLG sequencing prior to valproic acid (VPA) dosing in patients with seizures. Four patients who developed VPA-induced hepatotoxicity were examined for POLG sequence variations. A subsequent chart review was used to describe clinical course ...
Surges Rainer - - 2010
Generalized tonic-clonic seizures (GTCS) are a major risk factor for sudden unexpected death in epilepsy (SUDEP). We investigated whether ictal/postictal cardiac features were dependent on seizure type within individual patients. ECG data from patients with medically refractory temporal lobe epilepsy (TLE) undergoing presurgical investigation who had both complex partial seizures ...
Andersen Noémi Becser NB Danish Epilepsy Centre, Kolonivej 1, 4293 Dianalund, Denmark. - - 2010
Medication withdrawal (MW) is an important method of provoking seizures and activating epileptiform EEG activity during the diagnostic work-up of patients evaluated for epilepsy surgery. Previously it was suggested that MW might influence the seizure-type and activate cortical areas otherwise not producing epileptiform discharges, leading to a false localization of ...
Oehl Bernhard - - 2010
To assess latencies to the first typical generalized spike-wave discharge (GSWD) and clinically manifest seizure during long-term video-EEG monitoring (VEM) in patients with idiopathic generalized epilepsy (IGE). This is a retrospective analysis of continuous long-term VEM of 39 patients (25 women; mean age, 28.7 years). Mean duration of VEM was ...
Holmes Mark D - - 2010
OBJECTIVE: To compare the localization of the seizure onset zone estimated from ictal recordings with high spatial resolution, 256-channel scalp dense array electroencephalographic video long-term monitoring (LTM) with the aid of source analysis with that obtained from subsequent intracranial ictal recordings. METHODS: Ten patients with medically refractory epilepsy, all surgical ...
Wang Liang L Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, 1 You Yi Road, Chongqing 400016, - - 2010
In epilepsy, many studies were focus on apoE gene polymorphism and found APOE epsilon4 to be associated with earlier onset of temporal lobe epilepsy. There is not any study about apoE in cerebrospinal fluid (CSF) of epileptic patients, so we detect the CSF-apoE and determine whether it is changed after ...
Colicchio Gabriella - - 2010
PURPOSE: The aim of the study was to compare the outcome with respect to age of implant, aetiology and duration of epilepsy. METHODS: One hundred thirty-five drug-resistant epileptic patients, excluded from ablative surgery, were submitted to vagal nerve stimulation (1995-2007). Aetiology was cryptogenic in 57 and symptomatic in 78 patients. ...
Yang Zhixian - - 2010
OBJECTIVE: Startle epilepsy is one syndrome of reflex epilepsies. We studied its clinical and EEG characteristics. METHODS: Analysis of the clinical and EEG characteristics of startle epilepsy. RESULTS: Of 11 patients, five were female. Age of onset ranged from 5 months to 7.5 years. Abnormal etiologies were found in seven ...
Lodi Monica - - 2010
Kabuki syndrome (KS) is a rare dysmorphogenic disorder that is characterized by multiple congenital abnormalities with central nervous system involvement. The diagnosis is clinical and a variable degree of mental retardation is always present. Epilepsy is frequently reported, but a typical electroclinical pattern has not been described. We describe the ...
Woollacott Ione O C - - 2010
To maximize the efficiency of diagnostic video/EEG telemetry, we retrospectively studied the occurrence of clinical events during admission in 254 patients. One hundred fifty-nine patients had psychogenic nonepileptic seizures (PNES) and 95 had epileptic seizures (ES). Twenty-five with PNES and none with ES had an event before or during electrode ...
Badawy Radwa A B - - 2010
OBJECTIVE: Approximately 30% of patients with newly diagnosed epilepsy do not respond to antiepileptic drugs (AEDs), but this is not predictable. We used transcranial magnetic stimulation to determine the effect of AEDs on cortical excitability in patients with epilepsy and correlated this with a successful response to treatment. METHODS: Ninety-nine ...
Liu Kuan-Ting - - 2010
BACKGROUND AND PURPOSE: Transient hyperammonemia can occur after episodes of seizure. To verify that transient hyperammonemia is a unique finding in seizure patients, we compared the change in blood ammonia concentration during the postictal period with that of other patients who suffered consciousness disturbances due to other disorders. METHODS: We ...
Lohani Subash - - 2010
BACKGROUND: Despite optimal medical therapy, a sizeable number of patients continue to have persistent seizures. We evaluated the association of pretreatment and treatment variables with unfavorable seizure outcome. METHODS: Patients with follow-up over 12 years in the Nepal Epilepsy Association were evaluated. Patients having seizures for at least a year ...
Jeppesen Jesper - - 2010
To investigate whether epileptic seizures could be predicted or detected by means of spectral analysis of heart rate variability (HRV). Six patients with temporal lobe epilepsy (4 females, 2 males) participated in the prospective pilot study while enrolled for video/EEG monitoring (24 h/day, 2-4 days). ECG was continuously recorded and ...
Fishman Olga O Department of Neurology, Montefiore Medical Center, Bronx, NY 10467, USA. - - 2010
Periodic lateralized epileptiform discharges (PLEDs), an EEG pattern that is highly correlated with seizures, may represent an ictal pattern in some patients, but in other patients PLEDs persist despite the absence of seizures or after seizures have been controlled by anti-epileptic drugs. The tenacity of PLEDs was illustrated by continuous ...
Marek Bogdan B Department of Pathophysiology and Endocrinology, Medical University of Silesia, Zabrze, Katowice, Poland. - - 2010
A multitude of mechanisms have been implicated in the pathophysiology of epilepsy. To assess mean daily plasma concentrations of ACTH, cortisol, DHEAS, leu-enkephalin, and beta-endorphin in epileptic patients with complex partial seizures evolving to tonic-clonic in relation to frequency of seizure occurrence (groups with seizure occurrences - several per week ...
Poh Ming-Zher MZ Harvard-MIT Division of Health Sciences and Technology (HST), USA. - - 2010
We present a novel method for monitoring sympathetic nervous system activity during epileptic seizures using a wearable sensor measuring electrodermal activity (EDA). The wearable sensor enables long-term, continuous EDA recordings from patients. Preliminary results from our pilot study suggest that epileptic seizures induce a surge in EDA. These changes are ...
Sorensen Thomas L TL Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. - - 2010
An automatic alarm system for detecting epileptic seizure onsets could be of great assistance to patients and medical staff. A novel approach is proposed using the Matching Pursuit algorithm as a feature extractor combined with the Support Vector Machine (SVM) as a classifier for this purpose. The combination of Matching ...
Song Pil Sang - - 2010
Some patients with neurally mediated reflex syncope may be misdiagnosed as epilepsy because myoclonic jerky movements are observed during syncope. The seizure-like activities during the head-up tilt test (HUT) have been rarely reported. The purpose of this study was to assess the characteristics of these seizure-like activities and evaluate whether ...
Sakuma H - - 2010
OBJECTIVE: We conducted a nationwide multicenter study in Japan to elucidate the clinical and laboratory characteristics of acute encephalitis with refractory, repetitive partial seizures (AERRPS). MATERIALS AND METHODS: Clinical and laboratory features, treatment, and outcome were assessed using a structured questionnaire. RESULTS: Twenty-nine children were enrolled in the study. Refractory ...
Murkin John M - - 2010
BACKGROUND: In 2 separate centers, we observed a notable increase in the incidence of postoperative convulsive seizures from 1.3% to 3.8% in patients having undergone major cardiac surgical procedures. These events were temporally coincident with the initial use of high-dose tranexamic acid (TXA) therapy after withdrawal of aprotinin from general ...
Sinha S - - 2010
OBJECTIVE: To analyse the underlying causes, therapeutic response and outcomes of convulsive refractory status epilepticus (RSE). METHODOLOGY: This retrospective analysis was carried on 98 patients with RSE (age: 16.9+/-14.5 years). All had received a combination of parenteral benzodiazepine and phenytoin or phenobarbitone followed by other anti-epileptic drugs (AEDs). The clinical, ...
Alves-Leon Soniza Vieira - - 2009
BACKGROUND: Epileptic syndromes with absence seizures (AS) possess unique clinical and electroencephalographic (EEG) characteristics. In typical or atypical AS, ictal phenomenology may include various characteristics. Vídeo-EEG monitoring enables findings to be correlated with ictal phenomenology. OBJECTIVE: To evaluate the different AS in a cohort of patients with drug-resistant epilepsy (DRE) ...
Binder Devin K - - 2009
OBJECT: Prior studies suggest that aura semiology may have localizing value. However, temporal lobe aura characteristics and response to surgery have not been studied in large patient series. METHODS: The authors retrospectively analyzed the case records of 182 patients undergoing temporal lobectomy for medically intractable epilepsy at a single institution. ...
Seneviratne U - - 2009
The first seizure is more common than epilepsy. A detailed history is vital in the assessment in order to reveal unreported minor seizures such as myoclonic jerks, simple partial seizures and absences in the past. The first seizure could be provoked or unprovoked. Provoked seizures have a lower risk or ...
Muto Ayako - - 2010
PURPOSE: Rasmussen's encephalitis (RE) is a progressive and catastrophic epileptic disorder caused by chronic localized encephalitis. We performed a nationwide survey of RE to assess the clinical picture, treatment effect, and prognosis of Japanese RE patients. SUBJECTS & METHODS: The subjects were 27 patients (male:12; female:15) from 13 medical facilities. ...
Gelfand J M - - 2010
BACKGROUND: Cerebral perfusion-CT (PCT) is commonly used to image patients with suspected stroke, but PCT may also be useful in detecting abnormalities following seizure. METHODS: We retrospectively identified patients who presented to our stroke center between 2000 and 2008 with acute, transient neurological deficits because of seizure and received PCT ...
Ragona Francesca - - 2010
Aims of our study were to describe the early clinical features of Dravet syndrome (SMEI) and the neurological, cognitive and behavioral outcome. The clinical history of 37 patients with clinical diagnosis of SMEI, associated with a point mutation of SCN1A gene in 84% of cases, were reviewed with particular attention ...
Besocke Ana Gabriela - - 2009
The statistical concept of accuracy has never been applied to verify the history data collected on seizure disorders by open format interview. We compared patients'/witnesses' descriptions of epileptic seizures with videotaped seizure characteristics and analyzed the accuracy (ACC), sensitivity (SN), specificity (SP), false-positive rate (FPR), and false-negative rate (FNR) of ...
Caraballo Roberto H RH Neurology Department, Hospital Nacional de Pediatría Prof. Dr. Juan P Garrahan , Combate de los Pozos 1881, Buenos Aires, Argentina. - - 2009
To analyze the electroclinical features, aetiology and outcome in patients with normal neurological examination and psychomotor development who presented seizures during a mild gastroenteritis (MG). Evaluation of the clinical charts of 22 patients who were assessed in the Neurology Department, Hospital Nacional de Pediatría Prof. Dr. JP Garrahan between 1999 ...
Bakvis Patricia - - 2009
Previous studies have provided evidence for a vigilant attentional bias toward threat stimuli and increased basal diurnal cortisol levels in patients with psychogenic nonepileptic seizures (PNES). Because cortisol levels may be predictive of threat vigilance, we reanalyzed previous data on threat vigilance in 19 unmedicated patients with PNES and found ...
Surges Rainer - - 2010
PURPOSE: To determine whether abnormal cardiac repolarization and other electrocardiography (ECG) predictors for cardiac mortality occur in epilepsy patients and whether they are associated with an increased risk for sudden unexpected death in epilepsy (SUDEP). METHODS: In a matched-pair case-control study, recordings of adult patients with pharmacoresistant focal epilepsies who ...
Wilke Christopher C Department of Biomedical Engineering, University of Minnesota, 312 Church Street, Minneapolis, MN 55455, - - 2010
Determination of the origin of extratemporal neocortical onset seizures is often challenging due to the rapid speed at which they propagate throughout the cortex. Typically, these patients are poor surgical candidates and many times experience recurrences of seizure activity following resection of the assumed seizure focus. We applied a causal ...
Cheong J Y - - 2009
Rasmussen's encephalitis is a devastating illness characterized by intractable focal seizures due to chronic localised encephalitis. We report on a rare variant of delayed onset Rasmussen's encephalitis with triple pathology. A 27-year-old male, who was initially diagnosed with seizures when he was 16 years old, presented with focal seizures that ...
Starr Paul - - 2009
BACKGROUND: Delayed seizures have been reported with overdoses of bupropion extended-release (XL). This study systematically evaluates the frequency and timing of seizures and an association between other toxic effects (ie, agitation, tremors, and hallucinations) and seizures. METHODS: A 3-year multi-poison center observational study of hospitalized patients with ingestion of bupropion ...
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