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Karakoyun S S Department of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey, - - 2014
Inflammation has been reported to be associated with aortic dissection (AD), from the development to the prognosis of AD. In this study we aimed to find the role of the neutrophil-lymphocyte ratio (NLR) in the prediction of clinical events in patients with acute AD type A. The study comprised 37 ...
Weinmann Arndt A *Clinical Registry Unit (CRU) †Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University Mainz, Mainz ‡Department of Surgery **Department of Medical Oncology, National Center for Tumor Diseases (NCT), University Clinic of Heidelberg, Heidelberg §Department of Surgery, Kreuznacher Diakonie Hospital, Bad Kreuznach ∥Department of Internal Medicine I, University Clinic of Regensburg, Regensburg ¶Department of Internal Medicine, Hospital Konstanz, Konstanz #Department of Pathology, University Clinic of Düsseldorf, Düsseldorf, - - 2014
The aim of this study was to assess the long-term outcome of primary biliary cirrhosis (PBC) patients and to test the clinical value of various outcome models, such as the Mayo Risk Score (MRS), in a large single-center cohort in Germany. PBC is a chronic autoimmune liver disease with a ...
Kinfe Thomas M TM Division of Functional Neurosurgery and Neuromodulation, Rheinische Friedrich Wilhelms University, Bonn, Germany Department of Neurosurgery, Rheinische Friedrich Wilhelms University, Bonn, Germany - - 2014
Occipital nerve stimulation (ONS) results in beneficial outcomes, with marked pain relief, in otherwise intractable chronic migraine (CM) and chronic cluster headache (CCH). Some studies have reported that a positive response to occipital nerve block (ONB) administered prior to ONS predicts a positive response to ONS. However, other studies concerned ...
Acar H V HV Department of Anesthesiology and Intensive Care, Ankara Training and Research Hospital of Ministry of Health, Ankara, Turkey. - - 2014
A close relationship between obstructive sleep apnea (OSA) and difficult intubation has been suggested. We hypothesized that the STOP-Bang questionnaire, a screening tool for obstructive sleep apnea (OSA), can predict difficult intubation. In this prospective cohort study, 200 adult surgical patients undergoing surgery under general anesthesia were studied to evaluate ...
Zhang Rongbao R Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, - - 2014
The global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease (COPD) guidelines classify patients into four groups according to the number of symptoms and the level of future risk of acute exacerbation COPD (AECOPD). This study aimed to compare the results of different methods used in ...
Maurer Britta B Division of Rheumatology, University Hospital Zurich, Zurich, - - 2014
To identify predictive parameters for the progression of skin fibrosis within 1 year in patients with diffuse cutaneous SSc (dcSSc). An observational study using the EUSTAR database was performed. Inclusion criteria were dcSSc, American College of Rheumatology (ACR) criteria fulfilled, modified Rodnan skin score (MRSS) ≥7 at baseline visit, valid data ...
Jésus Pierre P INSERM Unit 1073, Rouen, France; Rouen University, Institute for Innovation and Biomedical Research, Rouen, France; Rouen University Hospital, Nutrition Unit, Rouen, - - 2014
The resting energy expenditure (REE) predictive formulas are often used in clinical practice to adapt the nutritional intake of patients or to compare to REE measured by indirect calorimetry. We aimed to evaluate which predictive equations was the best alternative to REE measurements according to the BMI. 28 REE prediction ...
Ellegaard Karen K The Parker Institute, Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark. - - 2014
The aim of this paper is to investigate sensitivity to change (SRM), predictive validity and discriminative ability of a quantitative (QS) and a semi-quantitative (SQS) Doppler ultrasound scoring systems in patients with rheumatoid arthritis (RA) treated with anti-TNF-α therapy. RA patients with wrist joint affection treated with TNF-α inhibitor were ...
Koukiasa Pagona P ICU Department, G. Papanikolaou Hospital, Thessaloniki, - - 2014
Background: Data on energy requirements of patients with spontaneous intracranial hemorrhage (SICH) are scarce. The objective of this study was to determine the resting energy expenditure (REE) in critically ill patients with SICH and to compare it with the predicted basal metabolic rate (BMR). Methods: In 30 nonseptic patients with ...
Du Hong - - 2014
Abstract Background: The objective of this study was to explore the role of laboratory parameters as early indicators of severity and as effective predictors of prognosis in patients with hemorrhagic fever with renal syndrome (HFRS). Methods: A total of 356 patients were enrolled in this study and were divided into ...
Fokkenrood H J P HJ Catharina Hospital, Department of Vascular Surgery, P.O. Box 1350, 5602 ZA Eindhoven, The Netherlands; Caphri Research School, Maastricht University, P.O. Box 606, 6200 MD Maastricht, The - - 2014
The daily life physical activity (PA) of patients with peripheral arterial disease (PAD) may be severely hampered by intermittent claudication (IC). From a therapeutic, as well as research, point of view, it may be more relevant to determine improvement in PA as an outcome measure in IC. The aim of ...
Camilo Millene R MR Neurology Division, Department of Neuroscience and Behavioral Sciences, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil. Electronic address: - - 2014
Obstructive sleep apnea (OSA) is frequent in acute stroke patients, and has been associated with higher mortality and worse prognosis. Polysomnography (PSG) is the gold standard diagnostic method for OSA, but it is impracticable as a routine for all acute stroke patients. We evaluated the accuracy of two OSA screening ...
Nieminen Anne - - 2014
Severe acute pancreatitis (AP) is associated with high morbidity and mortality. Early prediction of severe AP is needed to improve patient outcomes. The aim of the study was to find novel cytokines or combinations of cytokines for early identification of patients with AP at risk for severe disease. We performed ...
Park Ji Young - - 2014
Chronic eosinophilic pneumonia (CEP) is characterized by chronic eosinophilic infiltration of the lung. It is dramatically responsive to corticosteroid treatment, but symptoms and radiopacities recur frequently after tapering or discontinuing the medication. Fractional exhaled nitric oxide (FeNO) is a well-known noninvasive marker of eosinophilic airway inflammation. The aim of this ...
Vanderhelst Eef E Respiratory Division, University Hospital UZ Brussel, Vrije Universiteit Brussel, Brussels, - - 2014
Background: Treating acute infectious exacerbations in cystic fibrosis (CF) patients with intravenous antibiotic therapy leads to variability in lung function and the ventilation distribution response. Part of the variable lung clearance index (LCI) response could be associated with the variable peripheral effects of intravenous antibiotic administration. Objectives: We explored to ...
Ou Chih-Ying CY Division of Chest Medicine, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, - - 2014
Chronic obstructive pulmonary disease (COPD) is a pulmonary disease with systemic involvement. Several multidimensional indices have been developed to predict long-term outcomes. However, these indices have not been compared and validated in Taiwanese patients with COPD. A prospective, observational, hospital-based study was designed, and a total of 621 patients were ...
Dehghani Mohammad Reza MR Department of Cardiology - - 2014
Abstract Context: Leukocytes have been found to be the predictor of outcome following acute coronary syndrome (ACS). Objective: We sought to determine the relationship between leukocyte differentials and developing major adverse cardiac events (MACE) in patients with non-ST elevation ACS (NSTE-ACS). Materials and methods: A total of 490 consecutive patients ...
Karakas Ahmet A Ahmet Karakas, Assistant Professor, Department of Infectious Disease and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, Ankara, - - 2014
Objective: The aim of this pilot study was to determine clinical and laboratory factors that predict amputation surgery and to evaluate the predictive value of soluble CD14 (sCD14), interleukin-6 (IL-6), and procalcitonin (PCT) in patients with diabetic foot ulcers (DFUs). Methods: Twenty-seven (20 males, 7 females) Diabetic Foot Ulcers (DFU) ...
Lee Yonggu - - 2014
Carotid intima-media thickness (CIMT) and carotid atherosclerotic plaque (CAP) are well-known indicators of atherosclerosis. However, few studies have reported the value of CIMT and CAP for predicting renal artery stenosis (RAS). We investigated the predictive value of CIMT and CAP for RAS and propose a model for predicting significant RAS ...
Stolz Daiana - - 2014
The prevalence of exertional hypoxemia in unselected COPD patients is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) up regulation through the HIF-1 pathway. We aimed to assess the prevalence and the annual probability to develop exertional hypoxemia in stable COPD. We also hypothesized that increased ADM might be associated with ...
Cho Yeoungjee Y Department of Nephrology, Princess Alexandra Hospital, Brisbane, - - 2014
The ability of urinary biomarkers to predict residual renal function (RRF) decline in peritoneal dialysis (PD) patients has not been defined. The present study aimed to explore the utility of established biomarkers from kidney injury models for predicting loss of RRF in incident PD patients, and to evaluate the impact ...
Sternick Eduardo Back EB Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, - - 2014
Unlike in the Wolff-Parkinson-White syndrome, there has been no systematic study on the role of the pre-excitation pattern in predicting the ablation site in patients with atriofascicular (AF) pathways. We assessed in a large cohort the value of the 12-lead electrocardiogram (ECG) during antidromic tachycardia (ADT) to predict the site ...
Wehmeyer Malte H MH I. Department of Medicine, University Medical Center Hamburg-Eppendorf , Hamburg , - - 2014
Abstract Background and aims. Spontaneous bacterial peritonitis (SBP) is a life-threatening complication in patients with liver cirrhosis. The aim of this prospective study was to identify predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP. Patients and methods. Three hundred and ...
Ikeda Nobutaka N Division of Cardiovascular Medicine, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: - - 2014
The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) has previously been confirmed. Serum 1,5-anhydro-d-glucitol (1,5-AG) levels are a useful clinical marker for short-term glycemic status that reflect glycemic excursions with greater sensitivity compared with HbA1c, specifically in the postprandial state. Postprandial hyperglycemia is an important CAD ...
Yiu Kai-Hang - - 2014
High-sensitivity cardiac troponin I(hs-TnI) and T levels(hs-TnT) are sensitive biomarkers of cardiomyocyte turnover or necrosis. Prior studies of the predictive role of hs-TnT in type 2 diabetes mellitus(T2DM) patients have yielded conflicting results. This study aimed to determine whether hs-TnI, which is detectable in a higher proportion of normal subjects ...
Silva Jennifer N A JN Division of Pediatric Cardiology, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, - - 2014
Decreased intrathoracic impedance has been used in adults to predict heart failure (HF) exacerbations. A commercial algorithm, OptiVol® (Medtronic Inc., Minneapolis, MN, USA), identifies patients with decreased impedance. We sought to determine the specificity, sensitivity, and positive predictive value (PPV) of OptiVol for predicting HF exacerbation or increased arrhythmia burden ...
Raggam Reinhard B RB Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, - - 2014
The soluble urokinase plasminogen activator receptor (suPAR) reflects inflammation. However, the prognostic value of suPAR measurements, particularly at the very early onset of systemic inflammatory response syndrome (SIRS), is less well defined. The prognostic potential of suPAR levels in SIRS patients was evaluated. From November 2010 until April 2013, 902 ...
Riester Anna A Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität - - 2014
Context: Adrenal venous sampling (AVS) is used to distinguish bilateral from unilateral primary aldosteronism (PA). Due to its limited availability, clinical prediction scores have been proposed to diagnose unilateral disease without AVS. Objective: Our goal was to test two recently proposed predictors of unilateral PA: 1. A clinical prediction score ...
Somasundaram Sriramya S Department of Neurology, Goethe University Frankfurt, Frankfurt, - - 2014
Background and Purpose: Bedside evaluation of dysphagia may be challenging in left middle cerebral artery (MCA) stroke due to frequently existing aphasia. Here we analyse the predictive value of common bedside screening tests and of two items of cortical dysfunction, aphasia and buccofacial apraxia (BFA), for the detection of dysphagia. ...
Gursul Erdal E Buca Seyfidemirsoy State Hospital, Izmir, - - 2014
We aimed to evaluate whether heart rate variability (HRV) could predict prolonged asystole before head-up tilt table test (HUTT) by comparing time domain HRV parameters of patients with type 2B vasovagal syncope (VVS) and patients with other types of VVS. Ninety-eight patients who examined with 24-hour Holter electrocardiogram monitoring before ...
Mohammadi Afshin A Radiology Department, Urmia University of Medical Sciences, Urmia, West-Azerbaijan, Iran, Email: - - 2014
Pulmonary fibrosis is the main cause of mortality in patients with Systemic Scleroderma (SSc). This study was performed to investigate the utility of modified trans-thoracic ultrasound (TTUS) scoring system according to the comet tail sign (B-line artifacts) and to compare it with high-resolution computed tomography (HRCT) findings in patients with ...
Sun Ling L Southern Medical University, Guangzhou, Guangdong 510080, China; Department of Cardiac Pediatrics, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, - - 2014
Pulmonary hypertension (PH) is a common complication of congenital heart disease (CHD). Although risk stratification is vital for prognosis and therapeutic guidance, the need for understanding the role of novel biomarkers cannot be overlooked. The aim of the present study was to investigate the changes of homocysteine and hydrogen sulfide ...
Goodlad Catriona C Renal Section, Department of Medicine, Imperial College, London, United - - 2014
Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of long-term peritoneal dialysis (PD). There is no well-validated method for predicting which patients will develop the condition, although known risk factors include long duration of PD, high glucose exposure and lack of residual renal function. We have investigated whether ...
Tomita Kazunori K Intensive Care Unit, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, - - 2014
Complicated respiratory failure requiring mechanical ventilation in patients with type-B acute aortic dissection (AAD) has been previously reported, and inflammatory reactions have been found to be associated with the occurrence of oxygenation impairment (OI). However, the possibility of predicting the occurrence of OI in patients with type-B AAD has not ...
Franca Sara S Epilepsy Center, University Hospitals Neurological Institute, Case Western Reserve University, USA, Department of Neurology Centro Hospitalar de São João, Porto, - - 2014
Aim. To study new semiological signs which help distinguish between primary and secondarily generalised tonic-clonic seizures (GTCS). Methods. We retrospectively studied 86 GTCS, 13 primary and 73 secondary, in 58 patients who underwent video-EEG (vEEG) evaluation in our epilepsy monitoring unit. Eleven patients had generalised epilepsy and 47 focal epilepsy. ...
Aydoğdu Müge M Department of Chest Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey. - - 2014
Introduction: Unnecessary diagnostic tests are usually ordered to most of the patients with dyspnea or pleuritic chest pain, because of the worse outcomes of missed diagnosis of pulmonary embolism (PE). To identify rates and causes of over investigation for PE and to search whether it was possible to reduce this ...
Patel Bhavdip B Department of Anesthesia, King Khaled Eye Specialist Hospital, Riyadh, Saudi - - 2014
Intubation is often a challenge for anaesthesiologists. Many parameters assist to predict difficult intubation. The present study was undertaken to assess the validity of different parameters in predicting difficult intubation for general anaesthesia (GA) in adults and effect of combining the parameters on the validity. The anaesthesiologist assessed oropharynx of ...
Winstone Tiffany A - - 2014
Interstitial lung disease (ILD) is the leading cause of morbidity and mortality in patients with systemic sclerosis (SSc), however prognostication of SSc-ILD remains challenging. We conducted a systematic review to identify variables that predict mortality and ILD progression in SSc-ILD. Three databases were searched to identify all studies relating to ...
Alexandre Teixeira César C Centre for Informatics and Systems, University of Coimbra, Portugal. Electronic address: - - 2014
The ability of computational intelligence methods to predict epileptic seizures is evaluated in long-term EEG recordings of 278 patients suffering from pharmaco-resistant partial epilepsy, also known as refractory epilepsy. This extensive study in seizure prediction considers the 278 patients from the European Epilepsy Database, collected in three epilepsy centres: Hôpital ...
Naveau Sylvie S Departments of aHepatogastroenterology bBiochemistry and Hormonology cPathology, AP-HP, Antoine-Béclère Hospital dINSERM, U996, IPSIT, Clamart eUniv Paris-South, Faculty of Medicine Paris-South, Le Kremlin-Bicêtre, - - 2014
The PGAA index was one of the first composite liver fibrosis markers. This study aims, prospectively, to confirm the diagnostic value of PGAA and Fibrotest in patients with alcoholic liver disease and to compare their diagnostic performances. We prospectively included 200 consecutive patients (159 men and 41 women; mean age: ...
Wang Hong H Departments of *Infectious Diseases †Pathology, Zhejiang People's Provincial Hospital, Zhejiang, - - 2014
We aimed to develop a clinically useful scoring system to predict the probability of significant fibrosis (the Scheuer score ≥S2) in patients with chronic hepatitis B infection (CHB) and alanine aminotransferase (ALT) levels 2-fold lower than the upper limit of normal (ULN), in order to facilitate the clinical decision to ...
Pei Shujun S Anesthesia and Operation Center, Chinese People's Liberation Army General Hospital & Medical School of Chinese People's Liberation Army, Beijing 100853, People's Republic of China. Department of Anesthesiology, 251 Hospital of Chinese People's Liberation Army, Zhangjiakou 075000, People's Republic of - - 2014
Previous studies have shown that the stroke volume variation (SVV), the pulse pressure variation (PPV) and the pleth variability index (PVI) could be successfully used for predicting fluid responsiveness (FR) in surgical patients. The aim of this study was to validate the ability of SVV, PPV and PVI to predict ...
Wacker-Gußmann Annette A 1 I. Medizinische Klinik, Klinikum rechts der Isar der Technischen Universität München, München, - - 2014
OBJECTIVE. Preexisting renal impairment is a risk factor for contrast-induced nephropathy (CIN). In patients with creatinine in the upper normal level, cystatin C might be a more sensitive predictor of CIN than creatinine. Therefore, in this study, we investigated the usefulness of cystatin C to predict CIN. SUBJECTS AND METHODS. ...
Greve Anders M AM Department of Medicine B2142, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen OE, Denmark. - - 2014
Despite being routinely performed in the clinical follow-up of asymptomatic AS patients, little or no evidence describes the prognostic value of ECG findings in asymptomatic AS populations. This PhD thesis examined the correlates of resting 12-lead ECG variables with echocardiographic measures of AS severity and cardiovascular outcomes in the till ...
Prohić Džanela D 1Department of Gastroenterohepatology, University Clinical Center Sarajevo, 2Federal Minstry of Health; Sarajevo, Bosnia and - - 2014
Aim To evaluate the easily available laboratory and clinical markers in patients with decompensated cirrhosis and compare their prognostic value. Methods The study sample included a group of 80 patients with an established diagnosis of decompensated cirrhosis, hspitalizsed at the Department of Gastroenterohepatology, Clinical Center of the University of Sarajevo, ...
McCully Belinda H BH Trauma Research Institute of Oregon, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. Electronic address: - - 2014
Failed extubation and delayed tracheostomy contribute to poor outcomes in patients with a traumatic spinal cord injury (SCI). We determined if the level and completeness of SCI predict the need for tracheostomy. Data from 256 patients with SCI between C1 and T3 with or without tracheostomy were retrospectively analyzed. Logistic ...
Escudero Carolina A CA British Columbia Children's Hospital, Vancouver, British - - 2014
Paediatric electrocardiograms (ECGs) are ordered and interpreted by general paediatricians; however, no previous studies have evaluated the accuracy of their ECG interpretations. To determine general paediatricians' practice and opinions regarding ECG use, accuracy of their interpretation of paediatric ECGs, and the relationship between accuracy and self-perceived confidence. In the present ...
Jiménez David D Ramón y Cajal Hospital, IRYCIS, Respiratory Department, Madrid, Madrid, Spain ; - - 2014
Rationale: Not all patients with acute pulmonary embolism (PE) have a high risk of an adverse short-term outcome. Objectives: This prospective cohort study aimed to develop a multimarker prognostic model that accurately classifies normotensive patients with PE into low and high categories of risk of adverse medical outcomes. Methods: The ...
Skoglund Per H PH Karolinska Institutet, Department of Medicine, Solna, Internal Medicine Unit and Emergency Department, Karolinska University Hospital Solna, Stockholm, - - 2014
Patients with peripheral arterial disease (PAD) are at high risk for cardiovascular (CV) events. We have previously shown that ambulatory pulse pressure (APP) predicts CV events in PAD patients. The biomarkers amino-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hs-CRP), and cystatin C are related to a worse outcome in ...
Deutsch Eric C EC Department of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, , Philadelphia, Pennsylvania, - - 2014
Friedreich ataxia (FRDA) is a neurodegenerative disease caused by mutations in the frataxin (FXN) gene, resulting in reduced expression of the mitochondrial protein frataxin. Improved understanding of the pathophysiology of the disease has led to a growing need for informative biomarkers to assess disease progression and response to therapeutic intervention. ...
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