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Lee Yonggu - - 2014
Carotid intima-media thickness (CIMT) and carotid atherosclerotic plaque (CAP) are well-known indicators of atherosclerosis. However, few studies have reported the value of CIMT and CAP for predicting renal artery stenosis (RAS). We investigated the predictive value of CIMT and CAP for RAS and propose a model for predicting significant RAS ...
Stolz Daiana - - 2014
The prevalence of exertional hypoxemia in unselected COPD patients is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) up regulation through the HIF-1 pathway. We aimed to assess the prevalence and the annual probability to develop exertional hypoxemia in stable COPD. We also hypothesized that increased ADM might be associated with ...
Cho Yeoungjee Y Department of Nephrology, Princess Alexandra Hospital, Brisbane, - - 2014
The ability of urinary biomarkers to predict residual renal function (RRF) decline in peritoneal dialysis (PD) patients has not been defined. The present study aimed to explore the utility of established biomarkers from kidney injury models for predicting loss of RRF in incident PD patients, and to evaluate the impact ...
Sternick Eduardo Back EB Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, - - 2014
Unlike in the Wolff-Parkinson-White syndrome, there has been no systematic study on the role of the pre-excitation pattern in predicting the ablation site in patients with atriofascicular (AF) pathways. We assessed in a large cohort the value of the 12-lead electrocardiogram (ECG) during antidromic tachycardia (ADT) to predict the site ...
Wehmeyer Malte H MH I. Department of Medicine, University Medical Center Hamburg-Eppendorf , Hamburg , - - 2014
Abstract Background and aims. Spontaneous bacterial peritonitis (SBP) is a life-threatening complication in patients with liver cirrhosis. The aim of this prospective study was to identify predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP. Patients and methods. Three hundred and ...
Ikeda Nobutaka N Division of Cardiovascular Medicine, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: - - 2014
The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) has previously been confirmed. Serum 1,5-anhydro-d-glucitol (1,5-AG) levels are a useful clinical marker for short-term glycemic status that reflect glycemic excursions with greater sensitivity compared with HbA1c, specifically in the postprandial state. Postprandial hyperglycemia is an important CAD ...
Yiu Kai-Hang - - 2014
High-sensitivity cardiac troponin I(hs-TnI) and T levels(hs-TnT) are sensitive biomarkers of cardiomyocyte turnover or necrosis. Prior studies of the predictive role of hs-TnT in type 2 diabetes mellitus(T2DM) patients have yielded conflicting results. This study aimed to determine whether hs-TnI, which is detectable in a higher proportion of normal subjects ...
Silva Jennifer N A JN Division of Pediatric Cardiology, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, - - 2014
Decreased intrathoracic impedance has been used in adults to predict heart failure (HF) exacerbations. A commercial algorithm, OptiVol® (Medtronic Inc., Minneapolis, MN, USA), identifies patients with decreased impedance. We sought to determine the specificity, sensitivity, and positive predictive value (PPV) of OptiVol for predicting HF exacerbation or increased arrhythmia burden ...
Raggam Reinhard B RB Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, - - 2014
The soluble urokinase plasminogen activator receptor (suPAR) reflects inflammation. However, the prognostic value of suPAR measurements, particularly at the very early onset of systemic inflammatory response syndrome (SIRS), is less well defined. The prognostic potential of suPAR levels in SIRS patients was evaluated. From November 2010 until April 2013, 902 ...
Riester Anna A Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität - - 2014
Context: Adrenal venous sampling (AVS) is used to distinguish bilateral from unilateral primary aldosteronism (PA). Due to its limited availability, clinical prediction scores have been proposed to diagnose unilateral disease without AVS. Objective: Our goal was to test two recently proposed predictors of unilateral PA: 1. A clinical prediction score ...
Somasundaram Sriramya S Department of Neurology, Goethe University Frankfurt, Frankfurt, - - 2014
Background and Purpose: Bedside evaluation of dysphagia may be challenging in left middle cerebral artery (MCA) stroke due to frequently existing aphasia. Here we analyse the predictive value of common bedside screening tests and of two items of cortical dysfunction, aphasia and buccofacial apraxia (BFA), for the detection of dysphagia. ...
Gursul Erdal E Buca Seyfidemirsoy State Hospital, Izmir, - - 2014
We aimed to evaluate whether heart rate variability (HRV) could predict prolonged asystole before head-up tilt table test (HUTT) by comparing time domain HRV parameters of patients with type 2B vasovagal syncope (VVS) and patients with other types of VVS. Ninety-eight patients who examined with 24-hour Holter electrocardiogram monitoring before ...
Mohammadi Afshin A Radiology Department, Urmia University of Medical Sciences, Urmia, West-Azerbaijan, Iran, Email: - - 2014
Pulmonary fibrosis is the main cause of mortality in patients with Systemic Scleroderma (SSc). This study was performed to investigate the utility of modified trans-thoracic ultrasound (TTUS) scoring system according to the comet tail sign (B-line artifacts) and to compare it with high-resolution computed tomography (HRCT) findings in patients with ...
Sun Ling L Southern Medical University, Guangzhou, Guangdong 510080, China; Department of Cardiac Pediatrics, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, - - 2014
Pulmonary hypertension (PH) is a common complication of congenital heart disease (CHD). Although risk stratification is vital for prognosis and therapeutic guidance, the need for understanding the role of novel biomarkers cannot be overlooked. The aim of the present study was to investigate the changes of homocysteine and hydrogen sulfide ...
Goodlad Catriona C Renal Section, Department of Medicine, Imperial College, London, United - - 2014
Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of long-term peritoneal dialysis (PD). There is no well-validated method for predicting which patients will develop the condition, although known risk factors include long duration of PD, high glucose exposure and lack of residual renal function. We have investigated whether ...
Tomita Kazunori K Intensive Care Unit, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, - - 2014
Complicated respiratory failure requiring mechanical ventilation in patients with type-B acute aortic dissection (AAD) has been previously reported, and inflammatory reactions have been found to be associated with the occurrence of oxygenation impairment (OI). However, the possibility of predicting the occurrence of OI in patients with type-B AAD has not ...
Franca Sara S Epilepsy Center, University Hospitals Neurological Institute, Case Western Reserve University, USA, Department of Neurology Centro Hospitalar de São João, Porto, - - 2014
Aim. To study new semiological signs which help distinguish between primary and secondarily generalised tonic-clonic seizures (GTCS). Methods. We retrospectively studied 86 GTCS, 13 primary and 73 secondary, in 58 patients who underwent video-EEG (vEEG) evaluation in our epilepsy monitoring unit. Eleven patients had generalised epilepsy and 47 focal epilepsy. ...
Winstone Tiffany A - - 2014
Interstitial lung disease (ILD) is the leading cause of morbidity and mortality in patients with systemic sclerosis (SSc), however prognostication of SSc-ILD remains challenging. We conducted a systematic review to identify variables that predict mortality and ILD progression in SSc-ILD. Three databases were searched to identify all studies relating to ...
Alexandre Teixeira César C Centre for Informatics and Systems, University of Coimbra, Portugal. Electronic address: - - 2014
The ability of computational intelligence methods to predict epileptic seizures is evaluated in long-term EEG recordings of 278 patients suffering from pharmaco-resistant partial epilepsy, also known as refractory epilepsy. This extensive study in seizure prediction considers the 278 patients from the European Epilepsy Database, collected in three epilepsy centres: Hôpital ...
Naveau Sylvie S Departments of aHepatogastroenterology bBiochemistry and Hormonology cPathology, AP-HP, Antoine-Béclère Hospital dINSERM, U996, IPSIT, Clamart eUniv Paris-South, Faculty of Medicine Paris-South, Le Kremlin-Bicêtre, - - 2014
The PGAA index was one of the first composite liver fibrosis markers. This study aims, prospectively, to confirm the diagnostic value of PGAA and Fibrotest in patients with alcoholic liver disease and to compare their diagnostic performances. We prospectively included 200 consecutive patients (159 men and 41 women; mean age: ...
Wang Hong H Departments of *Infectious Diseases †Pathology, Zhejiang People's Provincial Hospital, Zhejiang, - - 2014
We aimed to develop a clinically useful scoring system to predict the probability of significant fibrosis (the Scheuer score ≥S2) in patients with chronic hepatitis B infection (CHB) and alanine aminotransferase (ALT) levels 2-fold lower than the upper limit of normal (ULN), in order to facilitate the clinical decision to ...
Pei Shujun S Anesthesia and Operation Center, Chinese People's Liberation Army General Hospital & Medical School of Chinese People's Liberation Army, Beijing 100853, People's Republic of China. Department of Anesthesiology, 251 Hospital of Chinese People's Liberation Army, Zhangjiakou 075000, People's Republic of - - 2014
Previous studies have shown that the stroke volume variation (SVV), the pulse pressure variation (PPV) and the pleth variability index (PVI) could be successfully used for predicting fluid responsiveness (FR) in surgical patients. The aim of this study was to validate the ability of SVV, PPV and PVI to predict ...
Wacker-Gußmann Annette A 1 I. Medizinische Klinik, Klinikum rechts der Isar der Technischen Universität München, München, - - 2014
OBJECTIVE. Preexisting renal impairment is a risk factor for contrast-induced nephropathy (CIN). In patients with creatinine in the upper normal level, cystatin C might be a more sensitive predictor of CIN than creatinine. Therefore, in this study, we investigated the usefulness of cystatin C to predict CIN. SUBJECTS AND METHODS. ...
Greve Anders M AM Department of Medicine B2142, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen OE, Denmark. - - 2014
Despite being routinely performed in the clinical follow-up of asymptomatic AS patients, little or no evidence describes the prognostic value of ECG findings in asymptomatic AS populations. This PhD thesis examined the correlates of resting 12-lead ECG variables with echocardiographic measures of AS severity and cardiovascular outcomes in the till ...
Prohić Džanela D 1Department of Gastroenterohepatology, University Clinical Center Sarajevo, 2Federal Minstry of Health; Sarajevo, Bosnia and - - 2014
Aim To evaluate the easily available laboratory and clinical markers in patients with decompensated cirrhosis and compare their prognostic value. Methods The study sample included a group of 80 patients with an established diagnosis of decompensated cirrhosis, hspitalizsed at the Department of Gastroenterohepatology, Clinical Center of the University of Sarajevo, ...
McCully Belinda H BH Trauma Research Institute of Oregon, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. Electronic address: - - 2014
Failed extubation and delayed tracheostomy contribute to poor outcomes in patients with a traumatic spinal cord injury (SCI). We determined if the level and completeness of SCI predict the need for tracheostomy. Data from 256 patients with SCI between C1 and T3 with or without tracheostomy were retrospectively analyzed. Logistic ...
Escudero Carolina A CA British Columbia Children's Hospital, Vancouver, British - - 2014
Paediatric electrocardiograms (ECGs) are ordered and interpreted by general paediatricians; however, no previous studies have evaluated the accuracy of their ECG interpretations. To determine general paediatricians' practice and opinions regarding ECG use, accuracy of their interpretation of paediatric ECGs, and the relationship between accuracy and self-perceived confidence. In the present ...
Jiménez David D Ramón y Cajal Hospital, IRYCIS, Respiratory Department, Madrid, Madrid, Spain ; - - 2014
Rationale: Not all patients with acute pulmonary embolism (PE) have a high risk of an adverse short-term outcome. Objectives: This prospective cohort study aimed to develop a multimarker prognostic model that accurately classifies normotensive patients with PE into low and high categories of risk of adverse medical outcomes. Methods: The ...
Skoglund Per H PH Karolinska Institutet, Department of Medicine, Solna, Internal Medicine Unit and Emergency Department, Karolinska University Hospital Solna, Stockholm, - - 2014
Patients with peripheral arterial disease (PAD) are at high risk for cardiovascular (CV) events. We have previously shown that ambulatory pulse pressure (APP) predicts CV events in PAD patients. The biomarkers amino-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hs-CRP), and cystatin C are related to a worse outcome in ...
Deutsch Eric C EC Department of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, , Philadelphia, Pennsylvania, - - 2014
Friedreich ataxia (FRDA) is a neurodegenerative disease caused by mutations in the frataxin (FXN) gene, resulting in reduced expression of the mitochondrial protein frataxin. Improved understanding of the pathophysiology of the disease has led to a growing need for informative biomarkers to assess disease progression and response to therapeutic intervention. ...
Sencan Arzu A Department of Pediatric Surgery, Dr. Behçet Uz Children's Trianing Hospital, Izmir, Turkey, - - 2014
To show whether Alvarado, Eskelinen, Lintula and Ohmann scoring systems have predictive values in diagnosing acute appendicitis in children. Sixty patients with suspected acute appendicitis were prospectively evaluated. Alvarado, Eskelinen, Lintula and Ohmann scores were calculated separately for each patient at the time of admission. The specificity, sensitivity, positive and ...
Jennings Douglas L DL 1 Department of Pharmacy Practice, Nova Southeastern University, Ft. Lauderdale - - - 2014
Purpose: To describe the pharmacokinetics of vancomycin in patients with continuous-flow left ventricular assist devices (CF-LVADs).Methods: Eligible patients were ≥18 years old, implanted with a Heart Mate II CF-LVAD during January 2008-April 2012, and treated with vancomycin ≥48 hours for infection. Key exclusion criteria were unstable renal function, acute heart ...
Otite Fadar F From the Department of Neurology, Stroke Division (F.O., S.M., A.M., S.C., S.O., F.A.S.), Department of Radiology (A.A.Z.), and Department of Neurosurgery (R.D.), Brigham and Women's Hospital, Boston, MA; Cardiovascular Research Laboratory and Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, MA (C.O.T.); Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA (S.P.); Harvard Medical School, Boston, MA (F.O., C.O.T., A.A.Z., A.M., S.C., S.O., S.P., R.D., F.A.S.); Department of Neurology, Klinikum Worms, Teaching Hospital of Mainz, Germany (S.M.); and Division of Neuroimaging and Neurointervention, Department of Radiology, University of Massachusetts Medical Center, Worcester, MA - - 2014
Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship between cerebral autoregulation and angiographic vasospasm (aVSP) and radiographic delayed cerebral ischemia (DCI) in patients with SAH. Sixty-eight patients (54±13 years) with a diagnosis of nontraumatic SAH ...
Korkmaz Ahmet - - 2014
There is little data regarding the diagnostic ability of neutrophil-lymphocyte ratio (NLR) in acute coronary syndrome. Therefore, we aimed to assess the predictive value of NLR in the discrimination of troponin-positive patients. We enrolled 244 patients (mean age 61.3 ± 11.7 years, 70.5% male) who presented to the emergency service ...
Williams K M KM 1] Experimental Transplantation and Immunology Branch, National Cancer Institute, NIH, Bethesda, MD, USA [2] Division of Blood and Marrow Transplantation, Center for Cancer and Blood Disorders, Children's National Medical Center, The George Washington University Medical Center, Washington, DC, - - 2014
Bronchiolitis obliterans syndrome (BOS) is a serious complication of chronic GVHD (cGVHD) following HSCT (hematopoietic SCT). The clinical diagnosis of BOS is based on pulmonary function test (PFT) abnormalities including: FEV1<75% predicted and obstructive FEV1/VC ratio, calculated using reference equations. We sought to determine if the frequency of clinical diagnoses ...
Sun Lin L Department of Cardiology, First Affiliated Hospital of Harbin Medical University, 23 Youzheng St, Nangang District, 150001 Harbin City, Heilongjiang Province, China. - - 2014
Objectives- We investigated whether transesophageal echocardiography (TEE) assisted with a computer-aided diagnostic (CAD) algorithm was superior to TEE in diagnosing left atrial (LA)/left atrial appendage (LAA) thrombi in patients with atrial fibrillation (AF) in a single prospective study. Methods- Transesophageal echocardiography was performed in patients with AF, and images were ...
As'habi A A Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of - - 2014
The present study was designed to determine the cutoff points for the diagnosis of mild-to-moderate and severe protein-energy wasting (PEW) based on dialysis malnutrition score (DMS) and malnutrition inflammation score (MIS), and the sensitivity, specificity, accuracy, area under receiver operating characteristic (ROC) curve, positive predictive value (PPV), negative predictive value ...
Tomaiuolo Giovanna G Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, Università di Napoli Federico II, Napoli, Italy ; CEINGE-Advanced Biotechnologies, Napoli, - - 2014
In cystic fibrosis (CF) patients airways mucus shows an increased viscoelasticity due to the concentration of high molecular weight components. Such mucus thickening eventually leads to bacterial overgrowth and prevents mucus clearance. The altered rheological behavior of mucus results in chronic lung infection and inflammation, which causes most of the ...
Palamaner Subash Shantha Ghanshyam G Department of Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, United States of - - 2014
Evidence is conflicting with regards to the role of vitamin D in statin induced myalgia (SIM). Studies so far have assessed cross-sectional association and were limited by study sample selected predominantly from cardiology clinics. In this retrospective cohort study we assessed the association between vitamin D and SIM and attempted ...
Cormio Luigi L Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71121 Foggia, - - 2014
Objectives. Normal and neoplastic human tissues have different electromagnetic properties. This study aimed to determine the diagnostic accuracy of noninvasive electromagnetic detection of bladder cancer (BC) by the tissue-resonance interaction method (TRIM-prob). Patients and Methods. Consecutive patients were referred for cystoscopy because of (i) microscopic or gross hematuria and/or irritative ...
Paredi Paolo - - 2014
Determining the site of airways inflammation may lead to the targeting of therapy. Nitric oxide (NO) is a biomarker of airway inflammation and can be measured at multiple exhalation flow rates to allow partitioning into bronchial (large/central airway maximal nitric oxide flux [J'awno]) and peripheral (peripheral/small airway/alveolar nitric oxide concentration ...
Hassan Eman M EM Department of Endemic Medicine and Hepatology, Cairo University, Cairo, - - 2013
Gastroesophageal varices are present in approximately 50% of patients with liver cirrhosis. The aim of this study was to evaluate liver stiffness measurement (LSM), Fib-4, Forns Index and Lok Score as noninvasive predictors of esophageal varices (EV). This prospective study included 65 patients with HCV-related liver cirrhosis. All patients underwent ...
Puliyel Mammen M Children's Center for Cancer and Blood Diseases, Division of Hematology, Hospital Los Angeles, Los Angeles, CA, - - 2013
Ferritin levels and trends are widely used to manage iron overload and assess the efficacy of prescribed iron chelation in patients with transfusional iron loading. A retrospective cohort study was conducted in 134 patients with transfusion-dependent anemia, over a period of up to 9 years. To determine if the trends ...
Wuister Annemarie M H AM Department of Otorhinolaryngology and Head & Neck Surgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The - - 2014
To assess the diagnostic value of nasal endoscopic findings in adults suspected of chronic rhinosinusitis. PubMed, EMBASE, and the Cochrane Library. A comprehensive search was performed up to March 5, 2013. Articles that assessed the diagnostic value of nasal endoscopy in adults suspected of chronic rhinosinusitis were included. For selected ...
Bohn Ethan - - 2013
Clinical outcomes of dialysis patients are variable, and improved knowledge of prognosis would inform decisions regarding patient management. We assessed the value of simple, chest X-ray derived measures of cardiac size (cardiothoracic ratio (CTR)) and vascular calcification (Aortic Arch Calcification (AAC)), in predicting death and improving multivariable prognostic models in ...
Park Ji Young - - 2013
The early identification of severe acute pancreatitis is important for the management and for improving outcomes. The bedside index for severity in acute pancreatitis (BISAP) has been considered as an accurate method for risk stratification in patients with acute pancreatitis. This study aimed to evaluate the comparative usefulness of the ...
Gebruers Nick N Department of Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium. - - 2013
Few studies have investigated how well early activity measurements by accelerometers predict recovery after stroke. First, we assessed the predictive value of accelerometer-based measurements of upper-limb activity in patients with acute stroke with a hemiplegic arm. Second, we established the difference in arm activity between hospitalized stroke and nonstroke patients. ...
Schniepp Roman - - 2013
Falls are common in patients with cerebellar ataxia (CA). Identification of gait variables associated with a higher risk of falls allows us to detect fallers and initiate protective procedures early. Gait variability, which is increased in CA patients, is a good predictor of falls in elderly subjects and patients with ...
Yarur Andres J - - 2013
The wide use of abdomino-pelvic computed tomography (APCT) in emergency departments (ED) has raised the concern for radiation exposure, costs and potential reactions to contrast agents. The aim of this study was to determine the yield and predictive factors for clinically actionable findings (CAF) in APCTs performed in patients with ...
Kasai Y - - 2013
Background: Portal vein embolization (PVE) is considered to improve the safety of major hepatectomy. Various conditions might affect remnant liver hypertrophy after PVE. The aim of the present study was to clarify the factors that affect remnant liver hypertrophy and to establish a prediction formula for the hypertrophy ratio. Methods: ...
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