Search Results
Results 201 - 250 of 1222
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Rhee John M - - 2009
STUDY DESIGN: Prospective case-control study. OBJECTIVE: To determine the prevalence and utility of commonly tested myelopathic signs in surgically treated patients with cervical myelopathy (CM). SUMMARY OF BACKGROUND DATA: Although physical signs are sought in making the diagnosis of CM, their importance remains unclear, as patients with CM may have ...
Roze E - - 2009
OBJECTIVE: The literature on propriospinal myoclonus (PSM) is poor and there are no systematic reviews of the subject. We sought to clarify the spectrum of PSM. METHODS: We first prospectively investigated all patients seen in our movement disorders clinic with a firm diagnosis of PSM between 2002 and 2007. All ...
Suttor V P - - 2009
The role of the central nervous system in enteroenteric motor reflexes remains controversial. Our aims were as follows: 1) to evaluate colorectal, rectocolic, gastrocolonic, and gastrorectal reflex responses in patients with cervical spinal cord injury (SCI) and 2) to compare these responses with those in healthy subjects. In six patients ...
Polomsky Marek - - 2009
BACKGROUND: Modern-day concepts about the pathogenesis of an intrathoracic stomach include crural diaphragm muscular deterioration, loss of phrenoesophageal ligament integrity, and presence of abdominothoracic pressure gradients. The role of spinal abnormalities has received little attention. Based on clinical observation, we hypothesized that kyphosis and other spinal diseases are components of ...
Tsirikos Athanasios I - - 2009
STUDY DESIGN: Retrospective review of a case series. OBJECTIVE: To present the clinical characteristics and progression of spinal deformity in patients with Sotos syndrome. SUMMARY OF BACKGROUND DATA: There is limited information on the development of spinal deformity and the need for treatment in this condition. METHODS: The medical records ...
Szecsi Johann - - 2009
OBJECTIVE: To compare isometric torque and cycling power, smoothness and symmetry using repetitive functional magnetic stimulation (FMS) and functional electrical stimulation (FES) in patients with paretic legs with preserved sensibility and in patients without sensibility. DESIGN: Repeated-measures design. SETTING: Laboratory setting. PARTICIPANTS: Eleven subjects with complete spinal cord injury (SCI) ...
Cristante A F - - 2009
A prospective, non-randomized clinical series trial. To evaluate the effect of autogenous undifferentiated stem cell infusion for the treatment of patients with chronic spinal cord injury (SCI) on somatosensory evoked potentials (SSEPs). A public tertiary hospital in São Paulo, Brazil. Thirty-nine consecutive patients with diagnosed complete cervical and thoracic SCI ...
Karamehmetoglu Safak Sahir - - 2009
The purpose of this study was to develop a quantitative skin impedance test that could be used to diagnose spinal cord injury (SCI) if any, especially in unconscious and/or non-cooperative SCI patients. To achieve this goal, initially skin impedance of the sensory key points of the dermatomes (between C3 and ...
Emmanuel A V - - 2009
Investigation of bowel function in 55 patients and 26 healthy volunteers using radiological, anorectal physiological and laser Doppler blood flow monitoring. Bowel dysfunction is common after spinal cord injury (SCI). We aimed to determine whether hindgut testing of autonomic innervation provides insight into presence of symptoms, altered motor function (transit) ...
Moviglia G A - - 2009
With the intention to ameliorate the clinical condition of patients with chronic spinal cord injury (SCI), a program that combines three cell therapies and an appropriate neurorehabilitation program were used to recreate and enhance the natural conditions of SCI repair. Vascularization recovery is approached by selective artery infusion of BMMNCs ...
Bot Joseph C J - - 2009
Multiple sclerosis is a diffuse disease of the central nervous system, and MRI of the spinal cord is highly recommended in the clinical evaluation of patients suspected of having multiple sclerosis. Within the new diagnostic criteria, spinal cord MRI increases sensitivity and possibly specificity for MS, but further work is ...
D'Aleo Giangaetano - - 2009
STUDY DESIGN: Case report. OBJECTIVE: To retrieve data about the utility of intrathecal baclofen for the treatment of otherwise refractory priapism that may occur in patients with spinal spasticity. SUMMARY OF BACKGROUND: Baclofen exerts well-known inhibitory effects on sexual function both in animals and humans. This observation led to the ...
Jagatsinh Yogendrasinh
<b>Background:</b> Spasticity is a major problem related to spinal cord injuries. Use of intrathecal baclofen with an implanted pump seems a very useful mode of therapy in patients in whom oral antispasmodic agents are either not effective or produce intolerable side-effects. <b> Materials and Methods:</b> Twenty-four patients with mean age ...
Pal Rakhi - - 2009
BACKGROUND AIMS: Spinal cord injury (SCI) is a medically untreatable condition for which stem cells have created hope in the last few years. Earlier pre-clinical reports have shown that transplantation of bone marrow (BM) mesenchymal stromal cells (MSC) in SCI-simulated models can produce encouraging results. In a clinical pilot study, ...
Deger Serpil Muge - - 2009
Hemodialysis patients are at an increased risk of bleeding due to the platelet dysfunction caused by uremia and the use of anticoagulants during dialysis. Spontaneous spinal hematoma is a rare disorder as a complication in hemodialysis patients. Also it includes the hematoma secondary to coagulopathy, vascular malformation and hemorrhagic tumors. ...
Vaidyanathan Subramanian - - 2009
Spinal cord injury patients are at risk for developing unusual complications such as autonomic dysreflexia while changing suprapubic cystostomy. We report a male patient with spina bifida in whom the Foley catheter was placed in the urethra during change of suprapubic cystostomy with serious consequences. A male patient, born in ...
Kam Alice - - 2009
To describe a case of fatigue associated with cardiomyopathy in a man with spinal cord injury. Case report. An obese 35-year-old man with long-term ASIA A L2 paraplegia, accompanied by a 2-year history of progressive severe fatigue. Physical examination showed obesity, hypertension, tachycardia, and pitting edema. An echocardiogram showed a ...
Zagólski O - - 2009
Electroglottography in the follow-up of bilateral vocal fold palsy. OBJECTIVES: The aim of the study was to determine if electroglottography provides useful information concerning vocal perturbations within the glottis in the follow-up of patients with bilateral vocal fold palsy. METHODOLOGY: Electroglottography was performed in 8 patients with bilateral vocal fold ...
Han Soo Jeong - - 2009
BACKGROUND/OBJECTIVE: In spinal cord injury (SCI), loss of central or peripheral neural control causes neurogenic bowel. Patients may not exhibit the typical signs and symptoms of gastrointestinal disease. Few studies have looked at the risk of gastrointestinal disease in this group and the indications for preventive screening. The objective of ...
Chelvarajah Ramesh - - 2009
INTRODUCTION: Upright posture confers numerous medical and social benefits to a spinal cord injured (SCI) patient. Doing so is limited by symptoms of orthostatic hypotension. This is a common secondary impairment among tetraplegic sufferers. OBJECTIVE: Establish the proportion of SCI patients who are restricted from using standing apparatus, such as ...
Muller-Putz Gernot R GR Laboratory of Brain-Computer Interfaces, Institute for Knowledge Discovery, Graz University of Technology, Krenngasse 37, 8010 Graz, Austria. - - 2009
Spinal cord injury (SCI) results in deficits of sensory, motor and autonomous functions, with tremendous consequences for the patients. The loss of motor functions, especially grasping, leads to a dramatic decrease in quality of life. With the help of neuroprostheses, the grasp function can be substantially improved in cervical SCI ...
van Middendorp J J - - 2009
Prospective multicenter longitudinal cohort study. To determine the relationship between improvements of the American Spinal Injury Association/International Spinal Cord Society (ASIA/ISCoS) neurological standard scale (AIS) outcome measure and improvements of functional ambulatory outcome measures in patients with traumatic spinal cord injury (SCI). European multicenter study of human SCI (EM-SCI). In ...
Pannek J - - 2009
Retrospective descriptive study. Although muscarinic receptors are the main targets for the treatment of detrusor overactivity today, anticholinergic therapy is not satisfying in a substantial percentage of patients. Recently, overexpression of P(2)X(2) receptors in patients with idiopathic overactive bladder was demonstrated, indicating that purinergic innervation may play an important role ...
Mowry E M - - 2009
BACKGROUND: Demyelinating events in relapsing-remitting multiple sclerosis (RRMS) can involve several locations in the central nervous system. We sought to determine if initial clinical demyelinating event (IDE) location predicts subsequent clinical relapse locations in early RRMS. METHODS: We identified all RRMS patients from two large MS clinics who were seen ...
Alshekhlee Amer - - 2008
The diaphragm pacing system (DPS) is a minimally invasive alternative to mechanical ventilation in patients with quadriplegia due to cervical myelopathy primarily caused by high cervical spinal cord injury. We evaluated 36 patients, 29 of whom had traumatic spinal cord injury, two who had a history of remote meningitis and ...
Marquardt Gerhard - - 2009
OBJECTIVE: To assess the potential prognostic relevance of serial serum measurements of S100B and NSE in patients with spinal intradural lesions. METHODS: Forty-four patients with spinal intradural lesions were included in this prospective study. S100b and NSE serum levels were measured on admission and daily after operative treatment. The pre-operative ...
Kanno H - - 2009
Retrospective data analysis. To clarify the clinical features and surgical management of spinal cord hemangioblastomas in patients with von Hippel-Lindau disease (VHL). Clinical VHL Research Group in Japan, Japan. Forty-eight out of 66 patients with associated spinal cord hemangioblastoma among 142 VHL patients were retrospectively examined with respect to clinical ...
Espinosa Gerard - - 2010
OBJECTIVE: To analyze the clinical and laboratory characteristics and outcomes of patients with transverse myelitis affecting more than 4 spinal segments secondary to systemic lupus erythematosus (SLE). METHODS: A computer-assisted (PubMed) search of the literature was performed to identify all cases of transverse myelitis affecting more than 4 spinal segments ...
Wynn Martha M - - 2009
Spinal fluid drainage reduces paraplegia risk in thoracic (TAA) and thoracoabdominal (TAAA) aortic aneurysm repair. There has not been a comprehensive study of the risks of spinal fluid drainage and how these risks can be reduced. Here we report complications of spinal fluid drainage in patients undergoing TAA/TAAA repair. The ...
Sun Xu - - 2008
BACKGROUND: Based on the "uncoupled neuro-osseous growth" theory, the hypothesized etiology of adolescent idiopathic scoliosis (AIS), a shorter spinal cord or a higher conus location, could be found in AIS patients. However, there are no case-control studies with large samples regarding the conus position in AIS patients. This study is ...
Alimoglu Orhan - - 2008
The identification of the risk factors associated with the increased incidence of the nerve injury is of paramount importance. Twenty-nine of 581 patients who developed recurrent laryngeal nerve palsy after thyroidectomy were analyzed retrospectively. There were 23 women (79%) and 6 men (21%), with a mean age of 45.6 years ...
Ulrich Dietmar - - 2009
INTRODUCTION: Dupuytren's disease is a fibroproliferative disorder characterized by thickening of the palmar fascia. Several studies indicate that MMPs and TIMPs may play a key role in the onset or progression of Dupuytren's disease and related disorders. In this study, we used a quantitative reverse-transcription PCR methodology to profile the ...
Lee Joon Woo - - 2008
OBJECTIVE: Our study was based on our hypotheses that in idiopathic acute transverse myelitis (ATM), fractional anisotropy (FA) values would be abnormal not only in the T2-hyperintense lesion but also in the surrounding normal-appearing spinal cord and that the abnormal FA values in the spinal cord could be related to ...
Heyer Christoph M - - 2008
RATIONALE AND OBJECTIVES: The study goal was to retrospectively evaluate the effectiveness of computed tomography (CT)-guided spinal biopsies. MATERIAL AND METHODS: Two hundred two CT-guided vertebral biopsies performed between May 1999 and June 2004 in 187 patients were retrospectively analyzed. Patient characteristics (age, sex, antibiotic therapy), technical parameters (depth and ...
Freivogel Susanna S Neurological Rehabilitation Hospital, Hegau Jugendwerk, Gailingen, Germany. - - 2008
To evaluate the feasibility of using a newly developed electromechanical gait device (LokoHelp) for locomotion training in neurological patients with impaired walking ability with respect to training effects and patients' and therapists' efforts and discomfort. design: Case series. setting: A neurological rehabilitation centre for children, adolescents and young adults. subjects: ...
Boster A - - 2008
BACKGROUND: Many patients referred to multiple sclerosis (MS) centers with symptoms suggestive of MS are found to have normal neurologic examinations, normal or non-specific brain magnetic resonance imaging (MRI) scan findings, and normal cerebrospinal fluid (CSF). Persistent symptoms often lead to multiple consultations and repeated diagnostic investigations. We performed a ...
Sugioka Takashi - - 2008
BACKGROUND: To our knowledge, no objective criterion has been identified for the diagnosis of lumbar spinal stenosis (LSS) and no study has evaluated the predictive value of self-reported patient information for the identification of LSS. OBJECTIVE: To develop and validate a prediction rule for the identification of LSS based on ...
Salvarani C - - 2008
BACKGROUND: Primary CNS vasculitis (PCNSV) is an uncommon disease in which lesions are limited to the brain and spinal cord. Our objective was to evaluate the frequency, clinical features, and outcome of spinal cord involvement in PCNSV. METHODS: We retrospectively identified 101 consecutive patients with PCNSV. Spinal cord involvement was ...
Ordu Gokkaya N K - - 2008
AIM: It has been previously shown that pulmonary function (PF) is significantly diminished in patients with osteoporosis (OP). But there are few data about the relationship between PF and aerobic capacity of osteoporotic patients and the severity of thoracic kyphosis and time since the diagnosis of OP. The aim of ...
Hwang Dae Woo - - 2008
Spinal epidural abscesses are uncommon, but potentially devastating and often fatal. They can be found in normal patients, but they are more prevalent in immunocompromised patients, such as intravenous drug users, diabetics, chronic renal failure patients, pregnant women, and others. Timely diagnosis and treatment are the keys to optimizing outcome. ...
Lutrzykowski Marek - - 2008
Two morbidly obese patients are presented. The first patient is a 38-year-old superobese female with BMI 56.2 in a wheelchair secondary to multiple sclerosis. The second patient is a 49-year-old female with BMI 47.7 confined to a wheelchair secondary to spinal cord transection due to a motor vehicle accident. Both ...
Soler Jean Marc - - 2008
INTRODUCTION: Orgasm is less frequent in men with spinal cord injury (SCI) than in able-bodied subjects, and is poorly understood. AIM: To assess the effect of autonomic stimulation on orgasm in SCI men using midodrine, an alpha1-adrenergic agonist agent. MATERIALS AND METHODS: Penile vibratory stimulation (PVS) was performed in 158 ...
Feldstein Neil - - 2008
Introduction The choice of surgical procedure for decompression of Chiari I malformations is often influenced by the presence of syringomyelia. The goal of this study was to determine if syringomyelia and/or scoliosis are influenced by dural opening versus nondural opening suboccipital decompressive (SOD) procedures. Methods A retrospective review of 54 ...
Agazaryan Nzhde - - 2008
Image-guided frameless extracranial radiosurgery has become an established treatment option; however, without a frame to restrict patient movements, intrafraction field mispositioning becomes more probable. The primary aim of this study is to determine the intrafraction motion of spinal radiosurgery patients. This aim was approached in two steps. First, a phantom ...
Kira Jun-Ichi - - 2008
Among 22 consecutive patients with myelitis, of unknown etiology, and atopic diathesis (atopic myelitis) who from April 2002 to March 2006 had been studied in our clinic, 5 (23%) showed focal amyotrophy in one or two limbs. These 5 patients were subjected to combined clinical, electrophysiological, neuroimaging and immunological studies. ...
Khaladj N - - 2008
OBJECTIVE: Detecting spinal cord ischemia early during replacement of the thoracoabdominal aorta remains a challenge. In a high risk population, we have re-evaluated the potential impact of ischaemia/damage markers (S100, lactate) in the peripheral blood and CSF for perioperative patient management. PATIENTS AND METHODS: Thirteen patients undergoing replacement of the ...
Zabjek Karl Franc - - 2008
BACKGROUND: The objectives of this study were to compare the postural characteristics of idiopathic scoliosis (IS) patients with different types of spinal curvature and to compare a motion capture and a sequential digitization technique to estimate the postural characteristics of the IS patients. METHODS: A total of 57 IS patients ...
Setzer Matthias - - 2008
STUDY DESIGN: Prospective evaluation of apolipoprotein E (APOE) genotypes in 106 consecutive patients with stenosis of the cervical spinal canal. OBJECTIVE: To determine the association between cervical spondylotic myelopathy (CSM) in patients with chronic spinal cord compression and the APOE genotype. SUMMARY OF BACKGROUND DATA: The APOE allele epsilon 4 ...
Kumru Hatice - - 2008
OBJECTIVE: Central nervous system reorganization following spinal cord injury (SCI) may cause functional changes in the motor tracts in patients in whom increased auditory startle responses (ASRs) have been previously reported. We hypothesized that if increased ASRs in patients with incomplete SCI were due to compensatory mechanisms, these changes would ...
Ozturk E - - 2008
OBJECTIVE: To present the magnetic resonance imaging (MRI) appearances of spinal split-cord malformation (SCM) and to investigate the various types of congenital spinal disorders associated with SCM. MATERIALS AND METHODS: MR examinations of 23 patients with SCM were carried out in our hospital between June 2002 and May 2007 and ...
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