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Chang Li L aDepartment of Neurology, The First Affiliated Hospital of Xinxiang Medical University bThe Adult Education College of Xinxiang Medical University, Xinxiang, Henan province, - - 2014
The prognostic value of the N-amino terminal fragment of the prohormone brain natriuretic peptide (NT-proBNP) in acute ischemic stroke (AIS) is uncertain. We sought to determine whether NT-proBNP levels were associated with functional outcomes after AIS. From August 2012 to October 2013, consecutive first-ever AIS patients admitted to the Department ...
Simopoulos V V Department of Cardiovascular and Thoracic Surgery, University Hospital of Larissa Medical School, University of Thessaly, Larissa, - - 2014
Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery. There exist consistent experimental and clinical data suggesting that aldosterone antagonists (AAs) may exert beneficial effects regarding electrical and structural remodeling in failing myocardium. Recently, eplerenone (EPL) has been found to reduce the incidence of nonsurgical AF when ...
Jorge Antonio José Lagoeiro - - 2014
Background: Heart failure with preserved ejection fraction (HFPEF) is the most common form of heart failure (HF), its diagnosis being a challenge to the outpatient clinic practice. Objective: To describe and compare two strategies derived from algorithms of the European Society of Cardiology Diastology Guidelines for the diagnosis of HFPEF. ...
Nedios Sotirios S Department of Electrophysiology, Heart Center, University of Leipzig, Germany. Electronic address: - - 2014
In patients with atrial fibrillation (AF), left atrial appendage (LAA) morphology has been suggested to modify risk for thromboembolic events (TE). In this study we tested the hypothesis that TE after AF catheter ablation (CA) is associated with LAA characteristics. Of 2,069 patients form the Leipzig Heart Center AF Ablation ...
Hansen Ditte - - 2014
The risk of cardiovascular disease is tremendously high in dialysis patients. Dialysis patients treated with vitamin D analogs show decreased cardiovascular morbidity and mortality compared with untreated patients. We examined the influence of two common vitamin D analogs, alfacalcidol and paricalcitol, on important cardiovascular biomarkers in hemodialysis patients. Anti-inflammatory effects ...
Momomura Shin-Ichi SI Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan, - - 2014
Adaptive servo-ventilation (ASV) therapy using an innovative ventilator-originally developed to treat sleep-disordered breathing (SDB)-is a novel modality of noninvasive positive pressure ventilation and is gaining acceptance among Japanese cardiologists in expectation of its applicability to treat patients with chronic heart failure (CHF) based on its acute beneficial hemodynamic effects. We ...
Müssigbrodt Andreas A Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany. Electronic address: - - 2014
Approximately 20-25% of the patients with hypertrophic cardiomyopathy (HCM) develop atrial fibrillation (AF) during the clinical course of the disease, a percentage significantly larger than that of the general population. The purpose of the present study was to report on the procedural results of patients with AF and either primary ...
Berezin Alexander E AE Internal Medicine Department, State Medical University, Zaporozhye, Ukraine. Electronic address: - - 2014
Acutely decompensated chronic heart failure (ADHF) is considered a life-threatening event. Despite contemporary treatment strategies of ADHF, frequent recurrent hospitalizations due to other cardiovascular reasons after discharge of patients from hospital occur. The objective of the study was to examine the prognostic value of circulating endothelial-derived apoptotic microparticles (EMPs) to ...
Poglajen Gregor G From the Department of Cardiology, Advanced Heart Failure and Transplantation Center (G.P., G.Z., B.V.), Department of Hematology (M.S., P.C.), and Department of Cardiovascular Surgery (I.K.), University Medical Center Ljubljana, Ljubljana, Slovenia; National Blood Transfusion Institute, Ljubljana, Slovenia (M.C.); and Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA (F.H., J.C.W., - - 2014
We investigated the effects of transendocardial CD34(+) cell transplantation in patients with ischemic cardiomyopathy. In a prospective crossover study, we enrolled 33 patients with ischemic cardiomyopathy with New York Heart Association class III and left ventricular ejection fraction <40%. In phase 1, patients were treated with medical therapy for 6 ...
Hoshiyama Fumiaki F Department of Urology, Osaka Kaisei Hospital, Osaka, - - 2014
To investigate the impact of obstructive sleep apnea syndrome (OSAS) on night-time secretion of brain natriuretic peptide (BNP) and antidiuretic hormone (ADH) in older men with nocturia accompanied by nocturnal polyuria. One hundred six men with nocturia aged ≥60 years underwent full-night polysomnography to determine whether they had OSAS. Blood count, standard ...
Lok Dirk J DJ University Medical Center Groningen, Groningen, The Netherlands; Deventer Hospital, Deventer, The - - 2014
A-type and B-type natriuretic peptides are established markers in chronic heart failure (HF). C-type natriuretic peptide (CNP) belongs to the same peptide family, but is predominantly localized in the endothelium. The prognostic role of CNP in heart failure has not been established. The aim of the study was to determine ...
Lima Marcelo Villaça MV Heart Institute (Instituto do Coração - InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São - - 2014
Adjunctive and non-pharmacological therapies, such as heat, for the treatment of heart failure patients have been proposed. Positive results have been obtained in clinically stable patients, but no studies of the use of thermal therapy in patients with decompensated heart failure (DHF) have been reported. An open randomized clinical trial ...
Chen Ping-An PA State Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China; Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China; Key Laboratory For Organ Failure Research, Ministry of Education of the People's Republic of China, Guangzhou, - - 2014
Myocardial energy expenditure (MEE) and 2-oxoglutarate are elevated in chronic heart failure (CHF) patients compared with healthy controls. To explore whether 2-oxoglutarate could reflect the levels of MEE and predict the prognosis of CHF, 219 CHF patients and 66 healthy controls were enrolled. 2-oxoglutarate was assayed with LC/MS/MS. CHF patients ...
Antonopoulos Alexios S AS From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom (A.S.A., M.M., P.C., J.D., R.P., N.N., T.D.K., R.L., S.N., K.M.C., C.A.); 1st Cardiology Department, Athens University Medical School, Athens, Greece (C.P., M.D., C.B., D.T.); Department of Cardiac Surgery, John Radcliffe Hospital, Oxford, United Kingdom (R.D.S., M.P., R.S.); and NIHR Oxford Musculoskeletal Biomedical Research Unit & Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom - - 2014
To explore the role of systemic inflammation in the regulation of adiponectin levels in patients with ischemic heart disease. In a cross-sectional study of 575 subjects, serum adiponectin was compared between healthy subjects, patients with coronary artery disease with no/mild/severe heart failure (HF), and patients with nonischemic HF. Adiponectin expression ...
Miura Masanobu M Department of Cardiovascular Medicine, Tohoku University Graduate School of - - 2014
Background:Although the need for nursing care (NC) in heart failure (HF) patients is recognized, detailed information on the current status in Japan is lacking.Methods and Results:In the CHART-2 Study, we obtained information on daily life, physical ability, nutrition and mental status for 4,174 patients (mean age, 67.1±10.8 years; 73.3% male) out of ...
Squara Fabien F Department of Cardiology, Pasteur University Hospital, Nice, - - 2014
Characterization of left atrial (LA) scar using bipolar voltage (BiV) mapping is not well defined. We have previously shown that BiV range of 0.2-0.45 mV can identify chronic scar from prior pulmonary vein isolation (PVI). This study sought to determine BiV range that can identify atrial inexcitable dense scar (IDS) ...
Faustino Ana - - 2014
Left atrial (LA) size is a predictor of cardiovascular outcomes in patients in sinus rhythm, whereas conflicting results have been found in atrial fibrillation (AF). This study aims to evaluate the accuracy of LA size to identify surrogate markers of an increased thromboembolic risk in patients with AF; assess the ...
Liu Qing Q From the Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Supported by the National Natural Science Foundation of China (grant no. 81170285) and the Research Fund for the Doctoral Program of Higher Education of China (grant no. 20101106110012). Q. Liu, MD; A. Dang, MD, PhD; B. Chen, MD; N. Lv, MD, PhD; X. Wang, MD; D. Zheng, MD, Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College. Address correspondence to Dr. A. Dang, Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. E-mail: amdang@fuwaihospital.org. Accepted for publication April 17, - - 2014
Increased levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with cardiovascular morbidity and mortality. Inflammation may also affect levels of NT-proBNP. We investigated the relationship of NT-proBNP with inflammation, disease activity, disease severity, and progression of Takayasu arteritis (TA). Plasma levels of NT-proBNP were determined in 68 patients with ...
Palomo-Piñón Silvia S Unidad de Investigación Médica en Enfermedades Nefrológicas, UMAE Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D.F., México. Electronic address: - - 2014
Residual renal function (RRF) has been identified as the most important component in dialysis adequacy and has a strong effect on clinical outcomes. This justifies any effort in understanding the mechanism behind the preservation or decline in RRF. The aim of this study was to analyze the possible association of ...
Christ Torsten T Departments of Pharmacology and Toxicology and t.christ@uke.de - - 2014
Atrial fibrillation (AF) is the most common heart rhythm disorder. Transient postoperative AF can be elicited by high sympathetic nervous system activity. Catecholamines and serotonin cause arrhythmias in atrial trabeculae from patients with sinus rhythm (SR), but whether these arrhythmias occur in patients with chronic AF is unknown. We compared ...
Ju Weizhu W Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, - - 2014
-Atrial tachycardias (ATs) following extensive ablation are increasingly common and challenging arrhythmias. The prolonged intra-atrial conduction time (IACT) during ATs in the milieu may complicate the mapping of focal ATs. The present study characterized the electrophysiological features of ATs in this unique setting and to further delineate an effective mapping ...
Stryjewski Piotr J PJ Cardiology Department, Chrzanow City Hospital, 16 Topolowa St., 32-500, Chrzanow, Poland, - - 2014
The aim of this study was to assess the clinical significance of N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in the differentiation of patients with cardiac and reflex syncope. The study included a group of 100 patients (56 women, 44 men), aged 18-77 years (mean 52.6 ± 16.7), with a history of reflex (group ...
Voight Jessica J Division of Cardiology, Veterans Administration Medical Center, Minneapolis, MN, USA; Department of Medicine, University of Minnesota, Minneapolis, MN, USA. Electronic address: - - 2014
Radiofrequency ablation (RFA) is considered a curative procedure for typical atrial flutter (AFL), however, patients remain at risk for developing new atrial fibrillation (AF). We sought to determine the incidence and predictors of new-onset AF and stroke after RFA of isolated AFL in a multicenter cohort. We included 315 consecutive ...
Mebazaa Alexandre A Université Paris Diderot, PRES Sorbonne Paris Cité and Saint Louis Lariboisière University Hospitals, U942 Inserm, Paris, France - - 2014
-Whether heart failure (HF) increases the risk of venous thromboembolism (VTE) is not well established. In the phase III MAGELLAN trial, extended-duration rivaroxaban was compared with standard-duration enoxaparin followed by placebo for VTE prevention in 8101 hospitalized acutely ill patients with or without HF. The aim of this analysis was ...
Stämpfli Simon F SF Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, - - 2014
We report the case of a young patient with repaired Ebstein's anomaly who developed severe tachycardia-induced cardiomyopathy and a large apical thrombus as a consequence of sustained atrial flutter with a 2:1 conduction. In spite of a dramatic course in hospital with prolonged mechanical resuscitation and extracorporeal membrane oxygenation, she ...
Sobczak Sebastian - - 2014
INTRODUCTION sST2 protein is a new biomarker. A prognostic value of sST2 in chronic heart failure (CHF) is still unclear. OBJECTIVES The evaluation of sST2 importance in patients with CHF at the 1-year follow-up after hospitalization for prediction: cardiovascular death, rehospitalization, need for increase diuretic therapy and/or worsening New York Heart Association ...
Wi Jin J Division of Cardiology, Department of Internal - - 2014
The mechanism of complex fractionated atrial electrogram (CFAE) in patients with atrial fibrillation (AF) remains controversial. This study investigated the relationship between CFAE and left atrial (LA) wall thickness. LA muscular wall thickness (excluding fat) was measured by cardiac computed tomography in 31 patients with AF (12 paroxysmal, 19 persistent) ...
Setoguchi Masahiko M Department of Cardiology, Kameda General Hospital, Kamogawa, Japan, - - 2014
Although there have been several studies regarding heart failure with preserved ejection fraction (HFpEF), investigations of the risk factors for readmission of Japanese patients with HFpEF remain scarce. Therefore, our goal was to identify the risk factors for readmission of Japanese patients with heart failure (HF), particularly those with HFpEF. ...
Alonso-Martínez José Luis JL Department A of Internal Medicine, Hospital Complex of Navarra, Irunlarrea 6, 31008 Pamplona, Spain. Electronic address: - - 2014
After an acute pulmonary embolism few long-term prognostic factors have shown to be of practical use. We hypothesized that, as in heart failure, natriuretic peptides could serve as biomarkers of a late deleterious prognosis. Consecutive patients admitted to an Internal Medicine ward diagnosed with acute pulmonary embolism were traced through ...
Miyazaki Shinsuke S Cardiovascular Center, Tsuchiura Kyodo Hospital, Tsuchiura, Ibaraki, Japan. Electronic address: - - 2014
The superior vena cava (SVC) is an infrequent but important source of atrial fibrillation (AF), but is not always easy to identify. This study aimed to identify predictors of an arrhythmogenic SVC (a-SVC) in patients undergoing AF ablation. Eight hundred thirty-six consecutive patients undergoing AF ablation were analyzed. All patients ...
Avci Anil - - 2014
Abstract Objectives. The aim of this study was to assess whether NLR levels are associated with echocardiographic parameters, New York Heart Association (NYHA) functional class, or B- type natriuretic peptide (BNP) levels in patients with idiopathic dilated cardiomyopathy. Design. Eighty-seven patients with idiopathic dilated cardiomyopathy were included prospectively from 2009 ...
Li Qin Q Division of Cardiology, Peter Munk Cardiac Center, Toronto General Hospital, Toronto, Canada - - 2014
-The aim of the study was to clarify the relationship between genotype status and major cardiovascular outcomes in a large cohort of Hypertrophic Cardiomyopathy (HCM) patients. -Genetic testing was performed in 558 consecutive proband HCM patients. Baseline and follow up (mean follow up 6.3 years) clinical and echocardiographic data were ...
Price Matthew J MJ Scripps Clinic, 10666 North Torrey Pines Road, Maildrop S1056, La Jolla, CA 92037. Electronic address: - - 2014
Atrial fibrillation (AF) is the most commonly sustained arrhythmia and is a major cause of stroke and systemic embolism. Chronic oral anticoagulation reduces this risk, but at the cost of increased bleeding. In addition, a substantial proportion of AF patients who are at moderate-to-high risk for stroke are undertreated due ...
Rangel Inês I Cardiology Department, Centro Hospitalar de S. João, Porto, - - 2014
Objective: To assess the prognostic significance of iron deficiency (ID) in a chronic heart failure (CHF) outpatient population. Methods and Results: We prospectively evaluated 127 patients with stable CHF and left ventricular ejection fraction ≤45%. Clinical and analytical data as well as information regarding the occurrence of the composite endpoint ...
Tate Samuel S Department of Internal Medicine, Division of Cardiovascular Medicine, University of California Davis, Davis, CA, - - 2014
Marked elevations of B-type natriuretic peptide (BNP) are not generally seen in patients with heart failure and preserved ejection fraction (HFpEF). The objective of this study was to examine the clinical and laboratory characteristics of a large cohort of patients with HFpEF and markedly elevated BNP. A retrospective examination of ...
Williams Matthew R MR University of California - San Diego & Rady Children's Hospital San Diego, San Diego, CA - - 2014
-Many patients with congenital heart disease require permanent pacing for rhythm management but cannot undergo transvenous lead placement. In others, epicardial scarring prohibits adequate sensing and pacing thresholds using epicardial leads. This study describes long-term lead performance using a transmural atrial (epicardial-to-endocardial) pacing approach in patients with congenital heart disease. ...
Ozcan Cevher C Cardiac Arrhythmia Service, Institute for Heart, Stroke and Vascular Care, Massachusetts General Hospital, Boston, MA, USA Division of Cardiovascular Medicine, University at Buffalo School of Medicine and Biomedical Sciences, NY, - - 2014
To determine the incidence and predictors of atrial fibrillation (AF) and its impact on survival in patients with other forms of supraventricular arrhythmias (SVAs) including atrial flutter (AFL), atrial tachycardia (AT), atrioventricular reentrant (AVRT), and AV nodal reentrant tachycardia (AVNRT). We hypothesized that SVA may increase risk of AF and ...
Zubaid Mohammad M Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait - - 2014
We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as ...
Bienias Piotr P Department of Internal Medicine and Cardiology with The Centre of Diagnosis and Treatment of Venous Thromboembolic Disease, The Medical University of Warsaw, Warsaw, - - 2014
Heart rate turbulence (HRT) impairment is a validated and an independent indicator of cardiovascular death. There are limited data on HRT in pulmonary hypertension (PH), so we assessed potential HRT alterations in PH, especially in relation to its severity. Thirty-three out of 41 patients were enrolled in the study aged ...
Zhang Han H the Emergency and Intensive Care Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
There have been several studies of atrial fibrillation (AF) over the past decades; however, data from Chinese patients are scarce. The aim of the study was therefore to describe the patient characteristics, risk profile and management strategies for Chinese AF patients presenting to emergency department (ED). We conducted a prospective, ...
Gong Hui H Division of Cardiology, Department of Medicine, Huashan Hospital of Fudan University, Shanghai 200040, P.R. - - 2014
Brain natriuretic peptide (BNP) is used as a prognostic biomarker for patients with heart failure (HF) in clinical practice, however, the correlation between BNP levels and the prognosis of HF in patients with reserved left ventricular systolic function (RLVSF) is not clear. Thus, the aim of the present study was ...
Qian Geng G Department of Cardiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, - - 2014
To investigate prognostic predictors of long-term survival of patients with cardiac amyloidosis (CA), and to determine predictive value of high-sensitivity cardiac troponin T (hs-cTnT) in CA patients. We recruited 102 consecutive CA cases and followed these patients for 5 years. We described their clinical characteristics at presentation and used a new, ...
Sokal Adam A Department of Cardiology, Congenital Heart Diseases and Electrotherapy. - - 2014
Currently cardiac resynchronization therapy (CRT) is recommended only for NYHA IV ambulatory patients. However, some recent reports showed that CRT can also be beneficial for the end-stage inotrope-dependent heart failure NYHA IV patients. In this report, we summarized results of CRT implantation in a group of eleven HF inotrope-dependent patients ...
Tsiachris Dimitris - - 2014
Hypertension (HTN) and chronic kidney disease (CKD) often coexist sharing common pathophysiological factors that both in combination and separately induce fibrotic changes in the heart provoking atrial fibrillation (AF). AF, per se, is associated with a 4- to 5-fold increased risk of stroke and a 2-fold increased risk of all-cause ...
Taneja Anil K AK Whipps Cross University Hospital, Barts Health NHS Trust, London, UK. Electronic address: - - 2014
Heart failure activates neurohormones, and elevated levels of brain natriuretic peptide (BNP) are associated with adverse outcomes. The SENIORS trial showed that nebivolol, a highly selective beta-1 antagonist with vasodilating properties, reduced the composite outcome of all cause mortality or cardiovascular hospital admissions in older patients with heart failure. We ...
Scholfield Michael M Department of Cardiology, University of South Florida, Tampa, FL. Electronic address: - - 2014
This study analyzed liver function abnormalities in heart failure patients admitted with severe acute decompensated heart failure (ADHF). A post hoc analysis was conducted using data from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE). Liver function tests (LFTs) were measured at seven time-points from ...
McMurray John J V JJ BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, - - 2014
To describe the baseline characteristics and treatment of the patients randomized in the Prospective comparison of ARNi with ACEi to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF), testing the hypothesis that the strategy of simultaneously blocking the renin-angiotensin-aldosterone system and augmenting natriuretic peptides with LCZ696 ...
Naccarelli Gerald V - - 2014
Dronedarone is an amiodarone analog that differs structurally from amiodarone in that the iodine moiety was removed and a methane-sulfonyl group was added. These modifications reduce thyroid and other end-organ adverse effects and makes dronedarone less lipophilic, with a shorter half-life. Dronedarone has been shown to prevent atrial fibrillation/flutter (AF/AFl) ...
Chanda Arijit A Bridgeport Hospital, Yale New Haven Health, Bridgeport, CT, USA, - - 2014
The relationship between obstructive sleep apnea (OSA) and increased risk for atrial fibrillation (AF) has been well established in previous studies. The relationship between OSA and silent AF is unknown. We hypothesized that patients with OSA but no known history of AF are at an increased risk for the arrhythmia ...
Pillarisetti Jayasree J Division of Cardiology-KU Cardiovascular Research Institute, University of Kansas Hospital & Medical Center, Kansas City, KS, 66195, - - 2014
Pre- and postablation atrial fibrillation (AF) brain natriuretic peptide (BNP) levels were shown to predict increased recurrence of AF following ablation. Our objective was to assess whether elevated BNP levels merely represent the presence of AF at the time of measurement or indeed the true recurrence of AF. In a ...
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