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Medina Laura L Ramón y Cajal University Hospital, Clinical Biochemistry - - 2014
The aim of the present study was to analyze whether absolute BNP and relative BNP changes values during follow-up of elderly patients with chronic HF could predict the development of acute decompensated episodes. A total population of 108 elderly outpatients with the diagnosis of HF was retrospectively reviewed. Available BNP ...
Pietrzak A A Department of Dermatology, Venereology and Paediatric Dermatology, Medical University, Lublin, - - 2014
Apparently, these days psoriasis is regarded as a systemic disease with frequent cardiovascular comorbidities, such as hypertension, myocardial infarction, valvular defects etc., which may lead to reduced lifespan or even sudden death. Therefore, it is important that biomarkers helpful in early detection or prediction of cardiovascular complications as well as ...
Roberts Matthew A MA Department of Renal Medicine, Eastern Health Clinical School, Monash University, Victoria, Australia;, †Department of Medicine, University of Melbourne, Victoria, Australia;, ‡Department of Cardiology, and, ‖Department of Nephrology, Austin Health, Victoria, Australia, §Melbourne Pathology Service, Collingwood, Victoria, - - 2014
B-type natriuretic peptide (BNP) concentration predicts outcome in patients undergoing dialysis. Because survival and cardiovascular risk change across the CKD continuum, serial changes in BNP were compared in patients at different CKD stages and after kidney transplantation. Patients with CKD stages 3 and 4 (CKD 3-4), dialysis patients, and kidney ...
Rothe Susanne S Clinic for Cardiac Surgery, Heart Centre Leipzig, University Leipzig, Leipzig, - - 2014
Background Increased body mass index (BMI) is often found to be a risk factor for cardiac disease. However, it is unclear whether BMI also affects the gap junction remodeling process in atrial fibrillation (AF). The aim of the study was to see if BMI can influence the connexin43 (Cx43) distribution in ...
Snaedal Sunna S Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, - - 2014
Background/Aims: N-Terminal pro-brain natriuretic peptide (NT-proBNP) is a predictor of cardiac events and death in the general population and in chronic kidney disease. There is limited information on how natriuretic peptides vary in dialysis patients. The aim of this study was to analyze NT-proBNP variability, factors predicting its variability and ...
Liu Hai - - 2014
The atrial fibrillation (AF) associated microRNAs (miRNAs) were found in the right atrium (RA) and left atrium (LA) from patients with rheumatic mitral valve disease (RMVD). However, most studies only focus on the RA; and the potential differences of AF-associated miRNAs between the RA and LA are still unknown. The ...
Ulimoen Sara R SR Department of Medical Research, Vestre Viken Hospital Trust, Baerum Hospital, Rud, Norway; Faculty of Medicine, University of Oslo, Oslo, - - 2014
Detectable levels of troponins are often found in serum of patients with atrial fibrillation (AF), and recent reports suggest that Tn concentrations are independently related to patient prognosis. We hypothesized that treatment with common rate-reducing drugs might lower the levels of cardiac troponin T (TnT) in patients with permanent AF. ...
Nishikawa-Takahashi M M Division of Cardiovascular Medicine, Department of Internal Medicine, Jichi Medical University School of Medicine, Tochigi, - - 2014
Chronic thromboembolic pulmonary hypertension (CTEPH) is a devastating disease, and treating patients with CTEPH who are not eligible for pulmonary endarterectomy is particularly challenging. Short-term bosentan or phosphodiesterase type-5-inhibitor treatment can greatly improve symptoms and hemodynamics in these patients; however, the long-term benefits of advanced pulmonary vasodilators are not known. ...
Tuluce Kamil K Ege University Faculty of Medicine, Department of Cardiology, Izmir, Turkey. - - 2014
We evaluated the associations among the well-known atrial fibrillation (AF) predictors including P-wave dispersion (PWD), intra- and interatrial electromechanical dyssynchrony (EMD), left atrial (LA) phasic functions, and plasma NT-proBNP levels, in patients with hypertrophic cardiomyopathy (HCM). Seventy patients with HCM and age and sex matched 70 subjects were enrolled. PWD, ...
Udell Jacob A JA Women's College Research Institute and Division of Cardiology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, - - 2014
To test two hypotheses: 1) Fibroblast growth factor (FGF)-23 identifies patients with stable ischemic heart disease (SIHD) at high risk of cardiovascular events independent of renal function, clinical factors, and established cardiovascular biomarkers; and 2) FGF-23 identifies patients who derive greater clinical benefit from ACE inhibitor therapy. FGF-23 is an ...
Mose Frank H - - 2014
Patients on chronic dialysis are at increased risk of vitamin D deficiency. In observational studies plasma 25-hydroxyvitamin D (p-25(OH) D) levels are inversely correlated with plasma BNP and adverse cardiovascular outcomes. Whether a causal relation exists has yet to be established. The aim of this study was to test the ...
Meijers Wouter C WC Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
Heart failure (HF) is a common disease and affects millions of patients worldwide. Diagnosis, risk assessment and treatment of HF are difficult and therefore there is a need for additional tools to improve clinical performance. Biomarkers may be helpful in this respect. Galectin-3 is a relatively new biomarker that has ...
Cui Jian J Penn State Hershey Heart and Vascular Institute, H047, Milton S. Hershey Medical Center, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA, - - 2014
Clinical reports have suggested that patients with heart diseases may be particularly vulnerable to heat injury. This review examines the effects of heat stress on cardiovascular and autonomic functions in patients with chronic heart failure (CHF). Laboratory investigations have shown that cutaneous vasodilator responses to heating are impaired in patients, ...
Xu Zhen-Xing ZX Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health, Department of Cardiology, Qilu Hospital of Shandong University, - - 2014
This study aimed to assess whether intra- and inter-atrial conduction delay could predict atrial fibrillation (AF) for paroxysmal supraventricular tachycardia (PSVT) patients after successful treatment by radiofrequency catheter ablation (RFCA). Echocardiography examination was performed on 524 consecutive PSVT patients (15 patients were excluded). Left atrial dimension, right atrial diameter and ...
Park Junbeom J Yonsei University Health system, Seoul, Republic of - - 2014
The clinical significance of left atrial pressure (LAP) has not yet been clearly elucidated in patients with atrial fibrillation (AF). The purpose of this study was to explore the effects of elevated LAP on pathophysiology and clinical outcome after radiofrequency catheter ablation (RFCA) in patients with AF. We measured LAP ...
Pan Hai-Yan - - 2014
Recombinant human B-type natriuretic peptide (rhBNP) has been indicated for the treatment of acute decompensated heart failure (ADHF). However, the therapeutic efficacy of intravenous rhBNP is not always satisfactory in patients with extremely high blood BNP levels. In this study, we evaluated the effects of rhBNP on patients with different ...
Vincenti Antonio A Electrophysiology and Cardiac Pacing Unit, San Gerardo Hospital, 20900 Monza, - - 2014
Atrial fibrillation (AF) incidence is high in end-stage renal disease (ESRD) patients, and haemodialysis (HD) session may induce paroxysmal AF episodes. Structural atrium remodelling is common in ESRD patients, moreover, HD session induces rapid plasma electrolytes and blood volume changes, possibly favouring arrhythmia onset. Therefore, HD session represents a unique ...
Peeters J M P W U JM Department of Cardiology, Maastricht University Medical Center, CARIM, P. Debyelaan 25, PO box 5800, 6202 AZ, Maastricht, the Netherlands, - - 2014
Heart failure (HF) management is complicated by difficulties in clinical assessment. Biomarkers may help guide HF management, but the correspondence between clinical evaluation and biomarker serum levels has hardly been studied. We investigated the correlation between biomarkers and clinical signs and symptoms, the influence of patient characteristics and comorbidities on ...
Hussain Sajjad S Department of Cardiology, Armed Forces Institute of Cardiology - National Institute of Heart Diseases, - - 2014
Objective: To determine the effectiveness of Seattle Heart Failure Model (SHFM) in a Pakistani systolic heart failure cohort in predicting mortality in this population. Study Design: Cohort study. Place and Duration of Study: The Armed Forces Institute of Cardiology - National Institute of Heart Diseases, Rawalpindi, from March 2011 to ...
Sakellaridis Timothy T 1 Cardiac Surgery Department, "Evangelismos" General Hospital, Athens, Greece ; 2 Cardiothoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Panorama, Greece ; 3 Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 4 Surgery Department (NHS), University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 5 Internal Medicine Department, "Theageneio" Anticancer Hospital, Thessaloniki, Greece ; 6 Cardiology Department, "Saint" Luke Private Hospital, Thessaloniki, Panorama, Greece ; 7 Anesthisiology Department, "Saint" Luke Private Hospital, Thessaloniki, Panorama, - - 2014
Atrial fibrillation (AF) is consider to be the most common cardiac arrhythmia with an increasingly prevalence. It is postulated that the source of thromboembolism in 90% of patients with non-valvular AF arises from the left atrial appendage (LAA). Stroke is the most feared and life threatening consequence of thromboembolism. Oral ...
Khalid Umair U Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, - - 2014
Atrial masses are uncommon, and mainly consist of tumors, vegetations and thrombi. Despite the availability of several imaging modalities, it may still be difficult to distinguish between them. Atrial thrombi seen in patients with systemic lupus erythematosus (SLE) usually occur in the setting of anti-phospholipid antibody syndrome, which confers a ...
Yin Qiu-Sheng QS Department of Geriatric Cardiology, General Hospital of Beijing Command of PLA, Beijing 100700, - - 2014
Heart failure (HF) is a common disease with complex pathophysiological causes. The diagnosis of HF commonly relies on comprehensive analyses of medical history and symptoms, and results from echocardiography and biochemical tests. Galectin-3, a relatively new biomarker in HF, was approved by the US Food and Drug Administration in 2010 ...
Edvinsson Marie-Louise ML Department of Emergency and Internal Medicine, Institute of Clinical Sciences Lund University, Lund University Hospital, SE- 221 85 Lund, - - 2014
Brain natriuretic peptide (BNP) is normally present in low levels in the circulation, but it is elevated in parallel with the degree of congestion in heart failure subjects (CHF). BNP has natriuretic effects and is a potent vasodilator. It is suggested that BNP could be a therapeutic alternative in CHF. ...
Yang Yan-Min YM Emergency and Intensive Care Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Contemporary clinical risk stratification schemata for predicting stroke and thromboembolism in patients with atrial fibrillation (AF) are largely derived from western cohorts. The purpose of the present study is to assess the potential risk factors for stroke and major adverse cardiac events (MACE) in a large population of Chinese AF ...
Amasyali Basri B Dumlupinar University, School of Medicine, Department of Cardiology, Kutahya, Turkey. Electronic address: - - 2014
Drug responses vary markedly from patient to patient in atrioventricular nodal reentrant tachycardia (AVNRT), the most common form of paroxysmal regular supraventricular tachycardia in adults. However, clinical and electrophysiological (EP) characteristics of patients with AVNRT whose tachycardia attacks could not be adequately controlled by antiarrhythmic agents have not been studied ...
Anselmino Matteo M Cardiology Division, Department of Internal Medicine, University of Turin, 10126 Turin, - - 2014
The previous literature has suggested that the iatrogenic atrial septal defects (IASDs) may follow left atrial (LA) access by transseptal (TS) puncture, especially in the case of a single TS for more than one catheter. The aim of the present study is to describe the prevalence of patent foramen ovale ...
Corradi Domenico D Department of Biomedical, Biotechnological, and Translational Sciences (S.Bi.Bi.T.), Unit of Pathology, University of Parma, Parma, Italy.. Electronic address: - - 2014
The extent to which atrial myocardium is remodeled in patients with persistent lone atrial fibrillation (LAF) is largely unknown. To perform a clinico-pathologic investigation in persistent LAF patients. We characterized structural and molecular remodeling in atrial biopsies from 19 patients (17 males, mean age 49 years) with persistent (>7days; n=8) ...
Siminiak Tomasz T Uniwersytet Medyczny w Poznaniu Centrum Medyczne HCP. - - 2014
Functional mitral regurgitation remains a significant clinical problem. Surgical valve repair has a high procedural risk. Thus, percutaneous techniques are under development. One of the most advanced devices for percutaneous mitral annuloplasty (PTMA) is the Carillon™ device. Brain natriuretic peptide (BNP) is a marker of haemodynamic status in heart failure ...
Viles-Gonzalez Juan F JF University of Miami Miller School of Medicine. - - 2014
Conduction disorders (CD) and atrial arrhythmias (AA) in the postoperative period of cardiac surgery impede prompt clinical recovery and prolong hospitalization. Mitral valve repair (MVR) has become the treatment of choice for patients with significant valvular regurgitation, but information on CD and AA in this population is scarce. Records of ...
Yamamoto Masayoshi M 1Cardiovascular Division, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, - - 2014
-In patients with atrial fibrillation (AF), most thrombus forms in the left atrial appendage (LAA). However, the relation of LAA morphology with LAA thrombus is unknown. -We prospectively enrolled 633 consecutive patients who were candidates for catheter ablation for symptomatic drug-resistant AF. Transesophageal echocardiography (TEE) was performed to assess LAA ...
Roldán Vanessa V From the Hematology and Medical Oncology Unit, Hospital Universitario Morales Meseguer, University of Murcia, Spain (V.R., J.G., V.V.); Departments of Cardiology (J.A.V., S.M.-F., E.J., C.M.P., M.V., F.M.) and Clinical Analysis (J.A.V., C.M.P.), Hospital Universitario Virgen de la Arrixaca, University of Murcia, Spain; and the University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK - - 2014
Oral anticoagulation is highly effective in reducing stroke and mortality in atrial fibrillation (AF). Several risk stratification schemes have been developed using clinical characteristics. Elevated levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) are important markers of increased mortality and morbidity in congestive heart failure and general community population. The aim ...
Wu Naqiong N Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, - - 2014
Backround N-terminal pro-brain natriuretic peptide (NT-proBNP) is a reliable predictor in acute coronary artery disease (CAD). Little is known about patients with stable CAD, especially Chinese patients with CAD. The aim of the present study was to investigate the association of NT-proBNP levels with the severity of CAD in patients ...
Verbrugge Frederik Hendrik FH Department of Cardiology, Ziekenhuis Oost-Limburg, Schiepse Bos 6, 3600 Genk, - - 2014
To assess the influence of device-registered episodes of atrial tachyarrhythmia (AT) on the response to cardiac resynchronization therapy (CRT).METHODS AND RESULTS: Consecutive CRT patients without history of atrial fibrillation (AF; n = 118) were followed prospectively. AT was defined as a device-registered episode of atrial rate >190 b.p.m. for ≥30 ...
Maron Barry J BJ Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota. Electronic address: - - 2014
In hypertrophic cardiomyopathy (HC), atrial fibrillation (AF) is an important determinant of clinical deterioration due to heart failure or embolic stroke. This study characterizes left atrial (LA) structural and functional parameters to establish markers predictive of AF risk, using cardiovascular magnetic resonance (CMR) imaging. We studied 427 consecutive patients with ...
Di Somma Salvatore S Department of Medical Sciences and Translational Medicine, University of Rome Sapienza, Sant'Andrea Hospital, - - 2014
Few data are available on diagnostic and prognostic role of quantitative fluid retention evaluated by bioelectrical impedance vector analysis (BIVA) in acute heart failure (AHF) patients at the moment of emergency department presentation. Point vectors and hydration index (HI) by BIVA were obtained in 381 patients referring to an emergency ...
Zhou Fan - - 2014
Abstract Relapse/refractory (R/R) multiple myeloma (MM) patients complicated with severe heart failure (NYHA class ? or ?) typically do not tolerate conventional chemotherapy. Our previous study indicated that R/R MM patients with severe comorbidities including severe heart failure could benefit from continuous low-dose oral cyclophosphamide 50mg and prednisone 15mg (CP ...
Kwak Jae Gun JG Department of Thoracic and Cardiovascular Surgery, Sejong General Hostpial, Bucheon, Republic of - - 2014
Atrial fibrillation (AF) in adult patients with atrial septal defect (ASD) accompanies an enlarged right atrium (RA) with a less enlarged left atrium (LA), which is the opposite situation in patients with AF and mitral valvular disease. This study was to compare the histopathological change in the atrium of patients ...
He Wenyan W Department of Cardiology, The First Affiliated Hospital of Chongqing Medical - - 2014
Comparison of the prognostic value of red cell distribution width (RDW) and N-terminal pro B-type natriuretic peptide (NT-proBNP) for short-term clinical outcomes in acute heart failure (AHF) patients has not been fully investigated.A total of 128 patients with AHF were enrolled and followed for 3 months. Primary endpoints were cardiovascular ...
Suzuki Hitoshi H Department of Arrhythmia and Cardiac Pacing, Fukushima Medical - - 2014
Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 2011, increased the ...
Perez Ana Cristina AC BHF Cardiovascular Research Centre, University of Glasgow, Glasgow, - - 2014
This study sought to examine the association between thyroid status and clinical outcomes in patients in the CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure) study. Hypo- and hyperthyroidism were associated with worse clinical outcomes in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial). In CORONA, 4,987 patients underwent baseline thyroid-stimulating ...
Rosa Gian Marco GM Gian Marco Rosa, Antonello Parodi, Ulrico Dorighi, Manrico Balbi, Claudio Brunelli, Clinic of Cardiovascular Diseases, Internal Medicine Department, San Martino Hospital and University of Genoa, 16143 Genoa, - - 2014
We present the case of a 74 year old woman suffering from severe mitral valve incompetence and rapid atrial fibrillation. After an appropriate vitamin K antagonist (VKA) therapy, the patient underwent mitral valve replacement by bioprosthesis. Then, the patient was re-hospitalized for jaundice. Suspecting hepatotoxicity, VKA was discontinued and fondaparinux ...
Koermendy Dezsoe D Department of Cardiology, Bern University Hospital, Bern, - - 2014
Objectives To assess feasibility and outcomes of left atrial appendage closure when using a patent foramen ovale for left atrial access. Background Due to the fear of entering the left atrium too high, using a patent foramen ovale (PFO) for left atrial access during left atrial appendage occlusion (LAAO) is ...
Celikbilek Asuman A Department of Neurology, Medical School, Bozok University, Yozgat, 66200, Turkey, - - 2014
Evidence suggests that symptoms of migraine are related to the involvement of the autonomic nervous system. Data on atrial conduction system are limited in migraineurs. We aimed to assess atrial electromechanical delay using tissue Doppler imaging (TDI) in patients with migraine. Forty-five migraine patients and age- and sex-matched 26 control ...
Yavaşi Ozcan O Recep Tayyip Erdoğan University, Rize Research and Training Hospital, Rize, - - 2014
Our aim was to determine if N-terminal pro-brain natriuretic peptide (NT-proBNP) or sonographic measurements of inferior vena caval (IVC) diameters and collapsibility index (IVC-CI) have a role in the monitoring of acute heart failure (AHF) therapy. Inferior vena caval diameters of 50 healthy people (control group) were measured to determine ...
Bisbal Felipe F Unitat de Fibril·lació Auricular (UFA), Hospital Clínic, Universitat de Barcelona, 08036 Barcelona, Catalonia, - - 2014
Pulmonary vein isolation (PVI) induces left atrial (LA) volume reduction, known as reverse remodelling (RR). The related changes in LA shape have not yet been evaluated. Left atrial sphericity (LASP) is a new shape-based marker of remodelling that compares LA geometry and a perfect sphere and is a powerful predictor ...
Kocyigit Ismail I Department of Nephrology, Erciyes University Medical Faculty, Kayseri, - - 2014
In this study our aim was to evaluate the relationship between degree of fluid status and arterial stiffness measured by pulse wave velocity (PWV) in peritoneal dialysis (PD) patients. Fluid status was determined by different methods including fluid overload measured by bioimpedance (Body Composition Monitor, BCM), calf normalized resistivity (CNR), ...
Demir Ali A Emergency Department, Numune Training and Research Hospital, Ankara 06370, Turkey. - - 2014
Head injury is the main cause of death among individuals younger than 45 years old. Cranial Computerized tomography (CT) is commonly used for diagnosis of head injury. Brain Natriuretic Peptide (BNP) is a peptide originally isolated from brain ventricles. The main aim of this study is to investigate BNP as ...
Rajendiran K S - - 2014
Heart failure (HF) is a common, debilitating disorder in which the heart is unable to pump an adequate blood supply to the tissues. Although it has been shown that inflammation occurs in HF, inflammatory markers have yet to be defined. Inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP), cytokines and ...
Sonmez Osman O Department of Cardiology, BezmiAlem Vakif University, Faculty of Medicine, Istanbul, - - 2014
Background Structural remodeling is associated with the fibroinflammatory process in the atrial extracellular matrix. In the present study we aimed to investigate whether serum levels of new circulating remodeling markers differ in patients with atrial fibrillation (AF) compared to patients with sinus rhythm. Material and Methods The study population included ...
Zecca Bruno B Emergency Care Unit, Fondazione IRCCS Ca' Granda OspedaleMaggiore Policlinico, Via F. Sforza 35, 20100 Milan, - - 2014
Background and Scope. Early etiologic diagnosis of ischemic stroke subtype guides acute management and treatment. We aim to evaluate if plasma biomarkers can predict stroke subtypes in the early phase from stroke onset. Methods. Plasma N-terminal prohormone of brain natriuretic peptide (NT-proBNP), D-dimer, C-reactive protein, serum albumin, and globulin levels ...
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