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Results 201 - 250 of 1873
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Saravia Silvia Gilka Munoz - - 2013
Chronic Chagas disease afflicts millions of patients in Latin America of which 70% remain asymptomatic but 30% develop fatal heart injury. To evaluate the impact of laboratory medicine for diagnosis and guiding of patients with Chagas' heart disease, we measured N-terminal B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT). ...
Brenyo Andrew - - 2013
-There are limited data regarding the prognostic implications of brain natriuretic peptide (BNP) assessment in mildly symptomatic heart failure (HF) patients who receive cardiac resynchronization therapy with a defibrillator (CRT-D). -The effect of elevated baseline and 1-year BNP levels (dichotomized at the upper tertile BNP of 120 pg/ml) on the ...
Purroy F - - 2013
The etiological classification of patients with transient ischaemic attack (TIA) is a difficult endeavor and the use of serum biomarkers could improve the diagnostic accuracy. The aim of this study was to correlate atrial fibrillation, the main cardioembolic etiology (CE), with different serum biomarkers measured in consecutive TIA patients. The concentrations ...
De Ponti Roberto - - 2013
 INTRODUCTION: Left atrial diverticula (LAD) have been reported to be (1) at risk for intracavitary thrombosis and cardiac perforation during ablation and (2) sites of extrapulmonary vein foci. In atrial fibrillation (AF) ablation, their presence might undermine procedure safety and efficacy. This observational study evaluates the morphology and clinical impact ...
Kottkamp Hans - - 2013
The atrial structure/substrate of patients with atrial fibrillation (AF) and clinically similar characteristics can present very differently, and also the 'phenotype' (i.e. paroxysmal, persistent, and long standing persistent) of the arrhythmia cannot comprehensively explain these differences. It was unclear why some patients stay in paroxysmal AF for decades, whereas other ...
Akoum Nazem - - 2013
Transesophageal echocardiography (TEE) is used to evaluate for left atrial appendage (LAA) thrombi prior to restoration of sinus rhythm in atrial fibrillation (AF). We examined the relationship of atrial fibrosis quantified using late gadolinium enhancement MRI (LGE-MRI) with TEE findings. We included 178 patients with AF, undergoing TEE and LGE-MRI ...
Marcos-Alberca Pedro - - 2013
OBJECTIVES: The aim of this study was to examine the feasibility of transthoracic two-dimensional (2D)-echocardiography in defining the cavo-tricuspid isthmus (CTI) anatomy and its value concerning the ease of catheter ablation of isthmic atrial flutter (AF). METHODS: CTI analysis was accomplished in 39 cases: 16 necropsy specimens and 23 patients. ...
Kim So Youn - - 2013
Intravenous immunoglobulin (IVIG) administered in the acute stage of Kawasaki disease (KD) is the standard therapy. Few reports describe nonresponders to initial treatment with IVIG in KD, which remains the most consistent risk factor for coronary artery lesions (CALs). This study aimed to investigate whether the serum level of N-terminal ...
Poulin Frédéric - - 2013
BACKGROUND: Atrial fibrillation (AF) is common in patients with heart failure. Rhythm- and rate-control strategies are associated with similar efficacy outcomes. We compared the economic impact of the 2 treatment strategies in patients with AF and heart failure from the province of Québec, Canada. METHODS: In a substudy of the ...
Kondo Yusuke - - 2013
BACKGROUND: Autonomic ganglionated plexi (GPs) play a significant role in the initiation and maintenance of atrial fibrillation (AF). GPs are key targets for a maze procedure. The purpose of this study was to identify the location of the left atrial GPs based on dense epicardial mapping during a maze procedure ...
Isakova Tamara T Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St., Miami, FL 33136, USA. - - 2013
In adults with heart failure, elevated levels of fibroblast growth factor 23 (FGF23) are associated with mortality. Data on FGF23 levels in pediatric heart failure are lacking. We conducted a cross-sectional study of 17 healthy children (mean age 13 years) and 20 pediatric patients with heart failure (mean age 12 ...
Golcuk Yalcin Y Department of Emergency Medicine, Bitlis State Hospital, Bitlis, Turkey. - - 2013
The main objective of this study was to determine a cutoff level of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) that could successfully predict the short- and long-term prognosis of patients with acute heart failure at the time of admission to the emergency department. The results of our study are presented ...
Gupta Manveen K MK Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, - - 2013
High fidelity genome-wide expression analysis has strengthened the idea that microRNA (miRNA) signatures in peripheral blood mononuclear cells (PBMCs) can be potentially used to predict the pathology when anatomical samples are inaccessible like the heart. PBMCs from 48 non-failing controls and 44 patients with relatively stable chronic heart failure (ejection ...
Delzell John E JE - - 2013
Dyspnea is a subjective experience of breathing discomfort; patients experience qualitatively distinct sensations that vary in intensity. Acute dyspnea might be secondary to an acute problem, or it might be an exacerbation of an existing disease (eg, asthma, chronic obstructive pulmonary disease, heart failure). It also accompanies a variety of ...
Alegre F - - 2013
Liver stiffness has been claimed to be increased in patients with heart failure. To determine the magnitude of this increase in liver stiffness, and to clarify whether it is related to the degree of heart failure or not. Twenty-six patients were prospectively collected, and divided in groups CHF (those with ...
Peleg Aviva - - 2013
The aim of the current study was to describe the role of corin, an enzyme that cleaves pro-atrial natriuretic peptide and pro-brain natriuretic peptide into their active peptides, in patients with acute coronary syndrome (ACS). Serum corin level was studied in patients with non-ST-elevation ACS who underwent percutaneous coronary intervention ...
Patel Taral K TK Division of Cardiology, Department of Internal Medicine, Northwestern University, Feinberg School of Medicine, 251 East Huron Street, Feinberg 8-503, Chicago, IL, 60611, - - 2013
Atrial fibrillation (AF) remains a major risk factor for stroke. Unfortunately, clinical trials have failed to demonstrate that a strategy of rhythm control--therapy to maintain normal sinus rhythm (NSR)--reduces stroke risk. The apparent lack of benefit of rhythm control likely reflects the difficulty in maintaining NSR using currently available therapies. ...
Ricci Renato Pietro RP Department of Cardiology, San Filippo Neri Hospital, Via Martinotti 20, Rome, Italy. - - 2013
Device-detected atrial fibrillation (AF) episodes predict poor clinical outcome regardless of symptoms. Potential benefits of remote monitoring are early arrhythmia detection and patient continuous monitoring. Several studies of device remote monitoring consistently demonstrated that AF represents the most common clinical alert and that detailed information on arrhythmia onset, duration, and ...
Jafri Lena - - 2013
BACKGROUND: The effect of impaired kidney function on B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) is vague. This study was performed to examine the effect of kidney dysfunction on the afore-mentioned markers and determine appropriate cutoffs for systolic heart failure (SHF). METHODS: In this cross sectional study adults with ...
Obokata Masaru - - 2013
OBJECTIVES: The purposes of this study were to examine left atrial (LA) functional reserve in patients with heart failure (HF) with preserved ejection fraction (HFpEF) and to determine whether LA strain has an incremental diagnostic value over clinical and conventional echocardiographic parameters. BACKGROUND: Patients with HFpEF have multiple cardiovascular reserve ...
Chen Yung-Lung - - 2013
BACKGROUND: The role of right atrial (RA) ablation guided by complex fractionated atrial electrograms (CFAE) in atrial fibrillation (AF) has been debated. This study evaluated the spatial distribution of RA CFAE, the critical sites, and the predictors of successful termination of longstanding persistent AF during RA ablation. METHODS: A total ...
Müller Patrick - - 2013
We evaluated if preoperative serum apoptosis markers correlate with atrial histological remodeling and postoperative atrial fibrillation (POAF) after cardiac surgery. A total of 33 patients with sinus rhythm (SR) and without history of atrial fibrillation (AF) undergoing cardiac surgery were prospectively enrolled. Serum concentrations of Fas (apoptosis-stimulating fragment ligand) and ...
Ellis Katrina L - - 2013
AIMS: Since their identification in the circulation, microRNAs have received considerable interest as putative biomarkers of cardiovascular disease. We have investigated the diagnostic utility of microRNAs in differentiating between patients with heart failure (HF) and non-HF-related breathlessness, and between HF with reduced (HF-REF) and preserved (HF-PEF) EF. METHODS AND RESULTS: ...
Godin Bénédicte - - 2013
Background: To gain further insights into mechanisms leading to atrial fibrillation (AF) recurrence after a first ablation procedure using cryoballoon technique, the data collected during redo procedure were analyzed. Methods and Results: From a total of 112 patients who underwent cryoballoon pulmonary vein isolation (PVI) for paroxysmal AF, 44 had a second ...
Niewinski Piotr - - 2013
Augmented peripheral chemoreflex response is an important mechanism in the pathophysiology of chronic heart failure (CHF). This study characterizes prevalence and clinical predictors of this phenomenon in optimally managed male CHF patients, and seeks to describe the hemodynamic consequences of chemoreceptor hypersensitivity. Thirty-four optimally managed CHF patients and 16 control ...
Beck-da-Silva Luís - - 2013
BACKGROUND: Anemia in heart failure patients and has been associated with increased morbi-mortality. Previous studies have treated anemia in heart failure patients with either erythropoietin alone or combination of erythropoietin and intravenous (IV) iron. However, the effect of IV or oral (PO) iron supplementation alone in heart failure patients with ...
Zhang Jing J Department of Nephrology, First Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of - - 2013
Lower heart rate variability implies increased risk of cardiovascular disease. This study aimed to evaluate the relationship between mineral metabolism and heart rate variability and longitudinal changes of heart rate variability after parathyroidectomy in stage 5 CKD patients. This cross-sectional study included 118 stage 5 CKD patients, 87 controls, and ...
Maeder Micha T - - 2013
Evaluation of: Vrtovec B, Knezevic I, Poglajen G, Sebesjen M, Okrajsek R, Haddad F. Relation of B-type natriuretic peptide level in heart failure to sudden cardiac death in patients with and without QT interval prolongation. Am. J. Cardiol. 111(6), 886-890 (2013). Guidelines recommend an implantable cardioverter defibrillator (ICD) for patients ...
Chintanaboina Jayakrishna - - 2013
BACKGROUNDAIMS: Several prognostic markers for heart failure (HF) have been determined but the importance of liver function tests (LFTs) remains unknown. The aim of this study was to determine the prognostic significance, if any, of abnormal LFTs in acute decompensated HF. All adult patients (> 18 years of age) who ...
Bazan Victor V Cardiology Department, Hospital del Mar, Parc de Salut Mar, UAB, 25 Passeig Maritim, 08003 Barcelona, Spain. - - 2013
The clinical yield of cavotricuspid isthmus (CTI) radiofrequency ablation of atrial flutter (AF) is limited by a high incidence of atrial fibrillation (AFib) in the long term. Among other acknowledged variables, the association of obstructive sleep apnea (OSA) could favor incomplete arrhythmia control in this setting. We assessed the impact ...
Ma Jinling - - 2013
BACKGROUND: Recent studies have suggested that carbohydrate antigen 125 (CA 125) serum levels are remarkably elevated in patients with heart failure. We hypothesized that there was a relationship between serum levels of tumor markers and the four stages of chronic heart failure (CHF) in patients aged 85years and older with ...
Horii Manabu - - 2013
BACKGROUND: Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are useful biomarkers for diagnosis and prediction of prognosis. Both of these peptides are elevated in patients with chronic kidney disease (CKD), but there is no evidence as to which peptide is the more suitable biomarker in patients with severe renal ...
Heck Pinar Bambul - - 2013
AIMS: N-terminal pro brain natriuretic peptide (NT-proBNP) is an important biomarker in congestive heart failure. This has also been confirmed in congenital heart disease. However, its clinical value in patients with different types of Fontan circulation remains questionable. METHODS AND RESULTS: We prospectively analysed 124 patients with various types of ...
Oflaz Mehmet Burhan - - 2013
BACKGROUND: There is no available published information about the atrial electromechanical coupling time (AEMCT) in patients with atrial septal defect (ASD). The aim of this study was to investigate the relationship between ASD and AEMCT obtained by tissue Doppler imaging (TDI). METHODS: A total of 35 patients with ASD and ...
Geske Jeffrey B - - 2013
OBJECTIVE: To determine the relation between B-type natriuretic peptide (BNP) and survival in patients with hypertrophic cardiomyopathy (HCM). BACKGROUND: Natriuretic peptides are released in response to neurohormonal activation, myocardial stretch, and wall tension, and therefore reflect hemodynamic derangements. METHODS: 772 patients with HCM had BNP obtained in conjunction with echocardiography ...
Kumagai Koji - - 2013
INTRODUCTION: Atrial substrates with high-dominant frequency (DF) and complex fractionated atrial electrogram (CFAE) sites have sources maintaining atrial fibrillation (AF) and are potential AF ablation targets. This study aimed to evaluate an approach of circumferential pulmonary vein isolation (PVI) followed by a DF and CFAE site ablation. METHODS AND RESULTS: ...
Lourenço P - - 2013
BACKGROUND:: Dipeptidyl peptidase IV (DPP IV) is a key enzime in B-type-natriuretic peptide (BNP) processing. DPP IV was never studied in human heart failure (HF). We aimed to measure DPP IV concentration in acute HF and determine its association with mortality. METHODS AND RESULTS:: Patientes hospitalized with acute HF were ...
van Veldhuisen Dirk J - - 2013
This study sought to determine the prognostic value of B-type natriuretic peptide (BNP) in patients with heart failure with preserved ejection fraction (HFPEF), in comparison to data in HF patients with reduced left ventricular (LV) EF (≤40%). Management of patients with HFPEF is difficult. BNP is a useful biomarker in ...
Wang Ji-Hung - - 2013
AIMS: Long-acting natriuretic peptide (LANP) is one of the peptide hormones in atrial natriuretic peptide (ANP) pro-hormone. Low levels of natriuretic peptide may lead to reduced lipolysis and excessive weight gain in obese patients. The aim of this study was to investigate the relationship between fasting serum LANP level and ...
Wieczorek Marcus - - 2013
AIMS: There are only few descriptions of patients without prior cardiac surgery in whom a large low-voltage zone (LVZ) or scar is the electrophysiological substrate for various atrial tachycardias. We describe the electrophysiological and electroanatomic characteristics of unusual macroreentrant atrial tachycardias (MRATs) in seven patients with spontaneous right atrial (RA) ...
Král Michal - - 2013
Multiple interactions are considered to occur among the various forms of cardiovascular and cerebrovascular diseases. The aim of this study was to assess the serum level profile of cardiac troponin T (cTnT) in patients with acute ischemic stroke (AIS) to evaluate factors associated with increased serum levels of cTnT. Patients ...
Hong Jin - - 2013
OBJECTIVE: The aim of this study was to assess left atrial (LA) functional remodeling in lone atrial fibrillation (LAF) patients via two-dimensional speckle tracking echocardiography (2DSTE). METHODS: Forty-five paroxysmal LAF patients and 30 healthy controls underwent 2DSTE in sinus rhythm. Longitudinal LA strain/strain rate (LAS/LASR) of booster, reservoir, and conduit ...
Kocabas S - - 2013
The use of a ventricular assist device (VAD) as a bridge to heart transplantation in the pediatric population has evolved over the past decades This article presents our institution's clinical experience in the anesthetic management of pediatric patients with end-stage heart failure who underwent implantation of a VAD between June ...
Lakhdhar R - - 2013
aim: Atrial septal defect (ASD) is one of the most common causes of congenital heart disease manifested in adulthood. Aim: To describe clinical and likelihood picture of adults over 60 years born with an ASD type II. methods: We performed a retrospective study of adult'sASD referred toourinstitutionfrom 1985 through 2010. ...
Ocak Tarık - - 2013
This prospective study investigated the diagnostic significance of the N-terminal pro-brain natriuretic (NT-proBNP) and troponin I peptides in emergency department patients presenting with palpitations. Two groups of patients with palpitations but without documented supraventricular tachycardia were compared: a group with supraventricular tachycardia (n = 49) and a control group (n = 47). Both groups ...
Baikampady Savitri Vasudev SV Ayurved consultant, Pune, Maharashtra, - - 2013
Heart failure (HF) is the inability of the heart to fill with or pump out enough blood to meet the body's needs. It is not one single disease, but rather a group of signs and symptoms caused by many different disease processes that have weakened the heart over time and ...
Jurisic Zrinka - - 2013
Objectives. To explore the relationship between IL-6 levels and echocardiographic abnormalities, and N-terminal probrain natriuretic peptide (NT-proBNP) levels in SSc patients and to correlate tested parameters with European Scleroderma Activity (EUSTAR) score.Methods. This case-control study included 31 SSc patients with preserved left ventricular ejection fraction (LVEF) and 32 matched healthy ...
Vélez-Martínez Mariella - - 2013
Previous studies have identified cardiac troponin I (cTnI) as an important marker in pulmonary hypertension (PH) prognosis. However, traditional assays are limited by poor sensitivity, even among patients at high risk. cTnI was measured in 255 PH patients using a new highly sensitive (hs) assay. Other measures included demographics, creatinine, ...
Badheka Apurva Omkar - - 2013
The effect of rate versus rhythm control in patients with atrial fibrillation who have undergone previous pacemaker (PM) implantation is unknown. We evaluated the mortality in patients with atrial fibrillation and a PM randomized to rate or rhythm control treatment strategies. The Atrial Fibrillation Follow-up Investigation of Rhythm Management data ...
Cotter Paul E PE Department of Neurosciences, Addenbrookes Hospital, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK. - - 2013
The usefulness of the implantable loop recorder (ILR) with improved atrial fibrillation (AF) detection capability (Reveal XT) and the factors associated with AF in the setting of unexplained stroke were investigated. A cohort study is reported of 51 patients in whom ILRs were implanted for the investigation of ischemic stroke ...
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