Search Results
Results 51 - 100 of 2199
1 2 3 4 5 6 7 8 9 10 >
Parshad Rajinder - - 2012
OBJECTIVES: Patients with achalasia have respiratory symptoms due to chronic microaspiration. Achalasia can lead to radiological and functional changes in the lung. We studied the effect of either balloon dilatation or laparoscopic Heller's cardiomyotomy on the reversal of these changes in the lung. METHODS: Thirty patients with achalasia were included ...
Allen D - - 2012
Introduction: We set out to determine the frequency of respiratory symptoms, abnormal lung function, and shrinking lung syndrome (SLS) among patients with systemic lupus erythematosus (SLE) and to determine correlates of SLS. Methods: Consecutive adult patients who fulfilled the American College of Rheumatology classification criteria for SLE were enrolled. Demographics, ...
Datta Jashodeep - - 2012
PURPOSE: Congenital diaphragmatic hernia (CDH) patients requiring extracorporeal membrane oxygenation (ECMO) were examined to determine, if aspects of their complex ventilatory management were associated with the development of chronic pulmonary hypertension (cPH). METHODS: CDH patients requiring ECMO from 1992 to 2007 were retrospectively reviewed. cPH was defined as pulmonary hypertension ...
Kawabata Yoshinori - - 2012
SUMMARY AT A GLANCE: A clinical study of patients with desquamative interstitial pneumonia was performed to assess the outcomes of long-term follow-up by high resolution computed tomography (HRCT). Of the 31 patients studied, 14 were followed-up for more than 60 months (mean 122 months). Five patients developed honeycombing on HRCT. ...
Kollert Florian - - 2012
OBJECTIVE: Vascular injury and endothelial cell (EC) activation are pathogenic hallmarks of systemic sclerosis (SSc). Human CD90 is highly expressed on activated ECs and can be shed from the cell surface. This study was conducted to examine whether soluble CD90 (sCD90) is elevated in the sera of patients with SSc ...
Güder Gülmisal - - 2012
Pulmonary restriction-a reduction of lung volumes-is common in heart failure (HF), rendering severity grading of chronic obstructive pulmonary disease (COPD) potentially problematic in subjects with both diseases. We compared pulmonary function in patients with either HF or COPD, or the combination to assess whether grading of COPD using the Global ...
Wilsher Margaret - - 2012
BACKGROUND: Pulmonary disease is a well recognised and important extra-articular manifestation of rheumatoid arthritis (RA). The objective of this study was to determine the prevalence of airway and parenchymal abnormalities in newly diagnosed patients with RA and to correlate these with clinical measures of RA severity and laboratory tests. METHODS: ...
Rialp Gemma - - 2012
BACKGROUND: The contribution of the central respiratory drive in the hypercapnic respiratory failure of neuromuscular diseases (NMD) is controversial. OBJECTIVE: To compare the CO₂ response and the duration of weaning of mechanical ventilation between a group of NMD patients and a group of quadriplegic patients due to intensive care unit ...
Gülhan Bora - - 2012
BACKGROUND: Niemann-Pick disease (NPD) and Gaucher disease (GD) are well-known lysosomal storage diseases. Respiratory system involvement is an important cause of morbidity and mortality in patients with NPD and GD. OBJECTIVES: We tried to assess the clinical, radiological, and histological features of GD and NPD patients with lung involvement. METHODS: ...
Tong Haixia - - 2012
AIM: To analyze the clinical and biological characteristics of adult BAL. METHODS: We identified 22 cases (4.4%) of BAL from 496 newly diagnosed acute leukemia patients and compared them with patients with acute myloid leukemia (AML) and acute lymphoblastic leukemia (ALL). RESULTS: CD34 positivity was higher in BAL (87%) than ...
Salaria Safia N - - 2012
Sessile serrated adenomas (SSAs) were unrecognized in pathology and gastroenterology practice until about 2005; we have diagnosed them since 2001, allowing up to 10 years of follow-up. We evaluated follow-up of patients with sessile serrated adenoma diagnosed between 2002 and 2004 in our teaching institution and compared it to follow-up ...
Labrador J - - 2012
All-trans retinoic acid (ATRA) induces complete remission in 64-100 % of patients with acute promyelocytic leukemia (APL), and is considered to be a safe agent. Pseudotumor cerebri is a neurological side effect of ATRA reported in pediatric patients, and which is characterized by raised cerebrospinal fluid pressure in the absence of ...
Chua Felix - - 2012
Objective. Interstitial lung disease (ILD) is an important feature of idiopathic inflammatory myositis (IIM). Factors associated with its development and progression remain incompletely understood. The authors report ethnicity differences and lung function trends that characterize the predilection for and natural history of ILD in a group of British patients with ...
Vossen Josephina A - - 2012
BackgroundPlasma D-dimer measurement is used in the assessment of the clinical probability of pulmonary embolism (PE), in order to minimize the requirement for pulmonary computed tomography angiography (CTA).PurposeTo evaluate whether doubling the threshold value of serum D-dimer from 500 µg/L to 1000 µg/L could safely reduce utilization of pulmonary CTA ...
Beyea Jason A - - 2012
OBJECTIVES/HYPOTHESIS: Transmastoid occlusion of the superior semicircular canal in superior semicircular canal dehiscence (SSCD) syndrome and the posterior semicircular canal in intractable benign paroxysmal positional vertigo (BPPV) will produce resolution of preoperative symptoms. STUDY DESIGN: Retrospective review, quality assurance. METHODS: Sixteen patients with SSCD and 61 patients (65 ears) with ...
Malik Numaan - - 2012
Decreased bone mineral density has been found in the advanced stages of various lung diseases. Limited data are available about prevalence and risk factors for osteoporosis/osteopenia (OP) in pulmonary arterial hypertension (PAH). Patients with PAH (either idiopathic or secondary to scleroderma [SSC-PAH]) who underwent bone density testing for lung transplant ...
Llor C - - 2012
Objective:  To assess the usefulness of a patient diary card of symptoms for monitoring the evolution of an exacerbation of chronic bronchitis (CB) and chronic obstructive pulmonary disease (COPD) in primary care. Method:  Multicentre, observational study. Patients with an exacerbation filled out a diary every day before bedtime during 10 days. ...
Oh John S - - 2012
In burned patients, inhalation injury can result in progressive pulmonary dysfunction, infection, and death. Although bronchoscopy is the standard for diagnosis, it only assesses the proximal airway and does not provide a comprehensive analysis of pulmonary insult. Chest radiographs have not been proven helpful in diagnosis of inhalation injury. Our ...
Hollak C E M - - 2012
Niemann-Pick disease (NPD) is a neurovisceral lysosomal storage disorder caused by acid sphingomyelinase (ASM) deficiency, which can be categorized as either Niemann-Pick disease type A [NPD-A], with progressive neurological disease and death in early childhood, or as Niemann-Pick disease type B [NPD-B], with a more variable spectrum of manifestations. Enzyme ...
Adler Christoph - - 2012
AIM OF THE STUDY: It has recently been suggested that acute kidney injury (AKI) may strongly be influenced by post-resuscitation disease and cardiogenic shock (CS), and may not just be a consequence of cardiac arrest and time without spontaneous circulation. AKI also has been suggested as a strong independent predictor ...
Legrand Céline - - 2012
OBJECTIVE: The aim of this study was to evaluate the outcome of patients with oesophageal atresia type III (EA), focusing on the presence of late sequelae and quality of life. METHODS: This was a retrospective case ascertainment followed by clinical assessment of patients. The study parameters included the patients' demographic ...
Kim Yu Jin - - 2012
Evidence suggests that diabetes mellitus (DM) is associated with idiopathic pulmonary fibrosis (IPF). According to the new IPF guidelines, high-resolution computed tomography (HRCT) is an essential means of diagnosing IPF. We investigated the relationship between IPF and DM in patients treated between 2003 and 2007. Newly diagnosed IPF patients in ...
Hsu Chien-Chin - - 2012
OBJECTIVES: Rapid determination of the inflammatory and sputum smear status in patients with pulmonary tuberculosis (PTB) is crucial for clinical decision making. The purpose of this study was to assess the relationship between gallium-67 (Ga-67) uptake by lung foci and sputum smear status in patients with PTB. We also attempted ...
Bradfield Jason - - 2012
Atrial Flutter and Pulmonary Hypertension. Background: Radiofrequency ablation is first-line therapy for atrial flutter (AFL). There are no studies of ablation in patients with severe pulmonary arterial hypertension (PAH). Methods: Consecutive patients with severe PAH (systolic pulmonary artery pressure >60 mmHg) and AFL referred for ablation were evaluated. Patients with ...
Bachert Claus - - 2012
BACKGROUND: The role of IgE in patients with severe asthma is not fully understood. OBJECTIVE: We sought to investigate whether IgE to Staphylococcus aureus enterotoxins might be relevant to disease severity in adult asthmatic patients. METHODS: Specific IgE antibody concentrations in serum against enterotoxins, grass pollen (GP), and house dust ...
Darze Eduardo S - - 2012
BACKGROUND: The diagnosis of pulmonary embolism (PE) still requires long work-up periods and multiple tests. OBJECTIVE: We aim to assess clinical outcomes after a negative investigation using a combined protocol of CT pulmonary angiography and CT venography (CTA/CTV) as a sole diagnostic test in unselected patients with suspected PE. METHODS: ...
Matsushima Soichiro - - 2012
Rationale: To assess ethnic sensitivity of indacaterol systemic pharmacokinetics in Japanese vs. non-Japanese patients. Methods: Analyses were in three parts: data from a single "all Asian" clinical study; and two on pooled data - one using a linear mixed effects (LME) model and the other a non-linear mixed effects (NLME) ...
Azab Noha A - - 2012
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been reported to be involved in the pathophysiology of some autoimmune diseases as systemic lupus erythematosus, ankylosing spondylitis, and multiple sclerosis. The aim of this study was to assess serum TRAIL concentration in systemic sclerosis (SSc) patients and to investigate its possible association ...
Olsson Karen M - - 2012
BACKGROUND: Atrial flutter and fibrillation are being increasingly reported in patients with pulmonary hypertension but little is known about their clinical implications. We sought to determine the incidence and clinical impact of these arrhythmias in patients with pulmonary hypertension. METHODS: In a 5-year, prospective study, we assessed the incidence of ...
Motoda Chikaaki - - 2012
BACKGROUND: The indications for catheter ablation have been expanded to include persistent atrial fibrillation (AF) to enable a high degree of sinus rhythm maintenance. We occasionally encounter patients undergoing pacemaker implantation in whom sick sinus syndrome became clinically evident after ablation. This study investigated whether underlying sinus node dysfunction (SND) ...
Lin Qionghua - - 2012
BACKGROUNDS: Copeptin has been studied as an excellent predictor of outcome in a variety of diseases, its value is even superior to that of B-type natriuretic peptide (BNP) in heart failure, but little is known about its characteristics in acute respiratory distress syndrome (ARDS)/acute lung injury (ALI). We sought to ...
Takeda Atsuya - - 2012
ABSTRACT BACKGROUND:Stereotactic body radiation therapy (SBRT) is standard care for patients with inoperable early-stage non-small-cell lung cancer. However, clinicians may hesitate to use SBRT in patients with severe COPD because of potential negative effects on pulmonary function. We quantitatively analyzed long-term declines in pulmonary function after SBRT to ascertain lifelong ...
Shimony Avi - - 2012
BACKGROUND: The incidence of pericardial effusion (PEF) during long-term follow-up among patients with pulmonary arterial hypertension (PAH) is unknown. We aimed to determine the incidence and prognostic significance of developing a new PEF among PAH patients. METHODS: Records of consecutive patients diagnosed with PAH between January 1990 and May 2010 ...
Kostrubiec Maciej - - 2012
OBJECTIVE: Various clinical and biochemical parameters predict the prognosis of patients with acute pulmonary embolism(APE). Treatment of APE can improve a patient's hemodynamic status, restoring adequate peripheral organ perfusion. Therefore, we hypothesized that improvement of renal function can predict short term prognosis of APE patients. MATERIAL & METHOD: We evaluated ...
Pelclová Daniela - - 2012
Leukotrienes (LTs) are involved in the pathogenesis of lung fibrosis and were increased in exhaled breath condensate (EBC) of the patients with pneumoconiosis. However the possible influence of extra-pulmonary disorders on the EBC markers is not known. Therefore in parallel with EBC, LTs' levels in the plasma and urine were ...
Stefanska J - - 2012
Chronic obstructive pulmonary disease (COPD) is predominantly the result of years of cigarette smoking. Increased oxidative stress in COPD derives from the increased burden of inhaled oxidants (cigarette smoke), air pollution and the increase in reactive oxygen and nitrogen species (ROS and RNS), generated by some inflammatory, immune, and structural ...
Albert Paul P School of Ageing and Chronic Disease, University Hospital Aintree, Lower Lane, Liverpool, - - 2012
Bronchodilator responsiveness is a potential phenotypic characteristic of chronic obstructive pulmonary disease (COPD). We studied whether change in lung function after a bronchodilator is abnormal in COPD, whether stable responder subgroups can be identified, and whether these subgroups experience different clinical outcomes. 1831 patients with COPD, 285 smoking (SC) and ...
Asakura Yuka - - 2012
Abstract Background: Recently, tiotropium Respimat(®) Soft Mist(™) Inhaler has been developed. Respimat is a multidose and propellant-free kit. The aerosol generated from Respimat improved lung drug deposition and required a lower dose of drug than HandiHaler(®). The aim of this study is to assess the effect of switching from tiotropium ...
Vujosevic Stela - - 2012
Treatment with pegylated interferon alpha (PegIFNα) and ribavirin is still regarded as the standard of care for chronic hepatitis C virus (HCV). Retinopathy has been occasionally described but prospective, longitudinal data are lacking. We investigated the frequency and clinical significance of retinopathy during therapy with PegIFNα and ribavirin in 97 ...
Okamoto Tsukasa - - 2012
Background: Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease induced by the inhalation of a variety of antigens. Patients with chronic HP often have a family history of pulmonary fibrosis. This strongly suggests that both genetic and environmental factors play an important role in the pathogenesis of chronic HP. ...
Gutiérrez Catalina - - 2012
INTRODUCTION: Chronic rhinosinusitis is very common in patients with cystic fibrosis. This can be explained by the unified airway concept, where the same pathophysiological phenomenon that affects the lungs, affects the paranasal sinuses. The management of these cases is difficult. OBJECTIVE: To describe the teamwork of otolaryngologists and bronchopulmonary specialists ...
Said Karim - - 2012
Background: Heart failure is prevalent in end-stage renal disease (ESRD) patients on long-term dialysis. Detection of right ventricular (RV) dysfunction before starting dialysis may help to identify patients at a higher risk of developing heart failure. Aim: To assess RV function in predialysis patients using tissue Doppler imaging (TDI) derived ...
Sato Mitsuyasu - - 2012
OBJECTIVE: To simplify the cough test to screen silent aspiration without sacrificing accuracy. STUDY DESIGN: Criterion standard. SETTING: Nihon University School of Dentistry Dental Hospital. PARTICIPANTS: 141 consecutive patients (92 men, 49 women; mean age, 71 ± 14 years; range, 23-94 years) who had complained of some dysphagic symptoms between ...
Isgoren Serkan - - 2012
OBJECTIVE: To assess the predictability of outcome and evaluate the factors that may lead to treatment failure in patients with Graves' disease who are treated with a single dose of radioiodine. MATERIALS AND METHODS: This is a retrospective study of 123 patients (M: 42; F: 81) with Graves' disease who ...
Kearney V - - 2012
Purpose: Evaluate the feasibility of using intra-fractional respiratory dominant eigenmodes of lung deformation as a method to track inter-fractional tumor regression and other physiological changes. Geometrical evaluation by dominant eigenmodes during free-breathing may be implemented as an IGART tool for assessing inter-fractional non-respiratory anatomical variation. Methods: Intra-fractional deformable image registration ...
Rodrigues Carlos Ewerton Maia - - 2012
OBJECTIVE: To describe the extra-articular manifestations (cardiac, renal, pulmonary, and neurological), usually not related to spondyloarthritis (SpA), in a large cohort of Brazilian patients. MATERIALS AND METHODS: This retrospective study analyzed 1,472 patients diagnosed with SpA and cared for at 29 health care centers distributed in the five major geographic ...
Zeng Qiaojun - - 2012
Chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) frequently coexist in clinical practice as they share the same risk factors. The manifestations of COPD and CHF are similar. Exertional dyspnoea, easy fatigability and reduced exercise tolerance are common to COPD and CHF and required careful interpretation. Pulmonary function ...
Stratton Amy - - 2012
Cystic fibrosis is an autosomal recessive disease typically diagnosed in early childhood secondary to pulmonary manifestations. We present the unusual case of a 20-year-old man being diagnosed with cystic fibrosis after he was incidentally noted to have an atrophic pancreas on magnetic resonance cholangiopancreatography. He had no sign of chronic ...
Zhao Zhanqi - - 2012
BACKGROUND: The feasibility of electrical impedance tomography (EIT) as an alternative examination tool in cystic fibrosis (CF) was examined. METHODS: 14 CF patients and 14 healthy volunteers were studied. Spirometry and EIT measurements were performed simultaneously. The global inhomogeneity (GI) index was applied to assess the degree of ventilation homogeneity ...
Frost Adaani E - - 2012
ABSTRACT BACKGROUND:The Registry to EValuate Early And Long-term Pulmonary Arterial Hypertension (PAH) Disease Management (REVEAL) is a multicenter, US-based, observational study of patients diagnosed with group 1 pulmonary hypertension enrolled consecutively from March 2006-December 2009. Of 3128 patients in this analysis, inclusion criteria permitted enrollment of 268 patients with mean ...
1 2 3 4 5 6 7 8 9 10 >