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Salunke Pravin P Department of Neurosurgery, PGIMER, Sector 12, Chandigarh, 160012, India, - - 2014
Certain abnormal contact points, appearing like additional joints (pseudofacets) were observed between atlas and axis in a subset of patients with congenital atlantoaxial dislocation (CAAD). The origin, function and bearing on management of such pseudofacets remain largely undetermined. The object is to study 'pseudofacets'or 'accessory joints' in patients with CAAD ...
Xiu Peng P Department of Orthopedics, Peking University Third Hospital, Beijing, - - 2014
Congenital C2-3 fusion (C2-3CF) is often involved in patients with atlantoaxial dislocation, and posterior occipitocervical fixation surgery is usually required. Hypoplasia of C2 pedicle is common in such patients, making C2 pedicle screws (PS) instrumentation inapplicable. Because of congenital fusion, C3PS instrumentation would be an ideal alternative for it will ...
Stein Benjamin E BE From the Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, - - 2014
Study Design. Retrospective data analysisObjective. To compare the trends in primary cervical spine fusion procedures in patients with rheumatoid arthritis (RA) against those in the general population.Summary of Background Data. RA severely impacts multiple joints in the body and can result in substantial deformity and functional impairment. Cervical spine involvement ...
Oatts Julius T JT Yale University School of Medicine, Department of Ophthalmology and Visual Science , New Haven , United States - - 2014
Abstract Background: Age-related distance esotropia (ARDET) is a form of acquired strabismus that affects elderly patients and manifests as an esotropia greater with distance fixation. Limited information exists regarding fusional amplitudes and deficient divergence in this disorder. Methods: In this retrospective study, patient characteristics, ocular alignment and motility, and clinical ...
Huang Kevin T KT Division of Neurosurgery, Duke University Medical Center, 100 Trent Drive, Blue Zone - Room 4529, Durham, NC - - 2014
Study Design. Retrospective review of a consecutive series of patients with radiologic evidence of spondylolisthesis.Objective. To establish the incidence and characteristics of spontaneous spinal arthrodesis (SSA) in the setting of lower lumbar spondylolisthesis.Summary of Background Data. Spontaneous spinal arthrodesis (SSA) of lumbar spondylolisthesis is a finding that is not discussed ...
Xu Risheng - - 2013
Study Design. Retrospective clinical studyObjective. To study the long-term effects of repeat cervical fusion after development of adjacent segment disease (ASD).Summary of Background Data. ASD is a well-recognized development after anterior cervical discectomy and fusion (ACDF). While there is data on the development of ASD after ACDF, the incidence of ...
Song Ji-Soo JS Department of Radiology, Chonbuk National University Hospital, Jeonju, Republic of - - 2013
This study aimed to determine the risk factors for developing adjacent segment disease (ASDz) after anterior cervical arthrodesis for the treatment of degenerative cervical disease by analyzing patients treated with various fusion methods. We enrolled 242 patients who had undergone anterior cervical fusion for degenerative cervical disease, and had at ...
Kasliwal Manish K - - 2013
Anterior cervical corpectomy and fusion (ACCF) is commonly performed for various pathologies involving the cervical spine. Although polyetheretherketone (PEEK) cages have been widely used following anterior cervical discectomy and fusion (ACDF), clinical literature demonstrating its efficacy following ACCF is sparse. A retrospective review of patients enrolled in a prospective database ...
Godts Daisy - - 2013
 To describe the clinical features of an under-recognised small esodeviation and horizontal diplopia on distance fixation seen in elderly patients not associated with lateral rectus underaction or coexisting neurological abnormalities.  87 elderly patients (age range 62-91 years) with constant or intermittent horizontal diplopia at distance were prospectively recruited and assessed ...
Abildgaard Lotte - - 2013
OBJECTIVES: Patients with acute myeloid leukaemia (AML) of the monocytic lineage often lack molecular markers for minimal residual disease (MRD) monitoring. The MLL-MLLT3 fusion transcript found in AML patients harbouring t(9;11) is amenable to RT-qPCR quantification but because of the heterogeneity of translocation breakpoints the MLL-MLLT3 fusion gene is a ...
Campbell Lynda J - - 2013
The diagnosis of acute promyelocytic leukaemia (APL) is usually confirmed by cytogenetics showing the characteristic t(15;17), but a minority of patients have a masked PML/RARA fusion. We report ten patients with APL and no evidence of the t(15;17), in whom the insertion of RARA into PML could not be demonstrated ...
Chen Bin-Bin BB Eye Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, - - 2013
To assess the quantitative association between anisometropia magnitude and the losses of resolution and contrast sensitivity; and to exemplify how the function of fusion and stereopsis vary with anisometropia magnitude (AM) in previously untreated anisometropic amblyopes. A total of 57 patients with previously untreated anisometropic amblyopia without strabismus (range: 8-35 ...
Zigler Jack E JE Texas Back Institute, Plano, Texas 75093, USA. - - 2012
The authors report the 5-year results for radiographically demonstrated adjacent-level degenerative changes from a prospective multicenter study in which patients were randomized to either total disc replacement (TDR) or circumferential fusion for single-level lumbar degenerative disc disease (DDD). Two hundred thirty-six patients with single-level lumbar DDD were enrolled and randomly ...
Dickman Curtis A - - 2012
We present a 16-year-old male patient with Marfan's syndrome who presented with quadriparesis from a Type I Chiari malformation (CM) with basilar invagination and a syrinx. The condition resolved after transoral odontoidectomy and occipitocervical fusion without posterior decompression of the CM. Thus, ventral decompression alone can resolve a cervical syrinx ...
Havens Joaquim M - - 2012
BACKGROUND: The effect of preinjury beta blockade on heart rate during initial trauma resuscitation is unclear. We hypothesized that preinjury beta blockade does not affect the heart rate response to initial trauma resuscitation. METHODS: A case-control study of patients admitted to a level I trauma center was conducted. Medical records ...
Benditt David G - - 2012
BACKGROUND: Although vasovagal syncope (VVS) is preceded by a surge of circulating catecholamines (epinephrine [Epi] and norepinephrine ]NE]) of adrenal/renal and synaptic origin, prevention of VVS with beta-adrenergic blockade has been ineffective except in 'older' VVS patients. OBJECTIVE: We hypothesized that in part, age-related differences of beta-blocker effect may be ...
Jacob Sony - - 2012
A few observational studies have shown the protective effect of statins on preventing ventricular tachycardia/ventricular fibrillation (VT/VF). However, the disparate study results prompt further exploration of this concept. We performed a meta-analysis to assess whether statin therapy is associated with a decrease in the incidence or recurrence of VT/VF in ...
Stankovic Ivan - - 2012
BACKGROUND: It has been suggested that patients with chronic HF and atrial fibrillation (AF) may respond differently to beta-blockers than those in sinus rhythm (SR). METHODS: In this predefined analysis of the CIBIS-ELD trial, a total of 876 chronic HF patients (164 patients with AF) were randomized to bisoprolol or ...
Bi Shu-Hong - - 2012
Background: Removal and control of excess fluid with dialysis is considered critical for protection against cardiovascular sequelae. Antihypertensive agents including beta-blockers may influence hemodynamics, which may limit fluid removal during hemodialysis (HD). Methods: Fifty chronic HD patients underwent bioimpedance measurement before and after a midweek dialysis session. Data on volume ...
Aksoy S M - - 2012
It has previously been shown that β-blocker therapy reduces QT dynamics in heart failure patients. The aim of this study was to demonstrate this improvement with the third-generation β-blocker, nebivolol. A total of 72 heart failure patients with systolic dysfunction were included in the study. Corrected QT (QTc) and QT ...
Di Minno Matteo Nicola Dario - - 2012
Little is known about tumor necrosis factor-α (TNF-α) blockers, disease activity, and liver steatosis (hepatic steatosis; HS) in subjects with psoriatic arthritis (PsA). We prospectively evaluated changes in HS during treatment with TNF-α blockers. In 48 patients with PsA who had evidence of HS before the beginning of TNF-α blocker ...
Ildarova Rukijat - - 2012
Four patients with long QT type 2, aged 11 to 18 years from unrelated families, with recurrent syncope and polymorhic ventricular tachycardia were studied. Long QT syndrome was diagnosed in these children at ages 4 to 7 years. Syncope, QT prolongation on electrocardiogram (corrected QT interval ≥490 milliseconds), notched T-wave ...
Suliburska Joanna - - 2012
Numerous hypotensive drugs result in decreasing the taste sensitivity or total loss of taste perception. The aim of this study was to evaluate the influence of selected groups of hypotensive drugs used in combined treatment of the taste sensitivity in patients suffering from primary arterial hypertension. The study was conducted ...
Kekow Joern - - 2012
To assess the efficacy of one course of rituximab (two 1-g doses) compared to an alternative tumor necrosis factor-α (TNFα) blocker in rheumatoid arthritis patients who had experienced one previous TNFα blocker failure (eg, etanercept, adalimumab, or infliximab). The efficacy of both treatments was studied in this retrospective, multicenter, noninterventional ...
Boxall Ben W J - - 2012
There is an inverse association between body mass and mortality in patients with chronic heart failure (CHF). Beta-blockers have been associated with weight gain. We wanted to examine the relation between beta-blocker use and weight in a population of patients with CHF. We weighed 276 patients presenting with CHF (mean ...
Liang Conrad W - - 2011
BACKGROUND: Neurogenic stunned myocardium (NSM) is a frequent complication of aneurysmal subarachnoid hemorrhage (aSAH), with a significant impact on disease course. The presumed cause is catecholamine surge at the time of aneurysm rupture. Beta-blockers, which reduce the impact of the catecholamine surge, may decrease the risk of developing NSM. METHODS: ...
Gerwig Marcus - - 2012
The objective of this study is to assess effects of beta-blocker migraine prophylaxis on cortical excitability determined by transcranial magnetic stimulation (TMS). Phosphene and motor thresholds (PT, MT) were investigated in 29 patients with migraine, in 15 of them prior to and following preventive medication with metoprolol and in 14 ...
Kiko Takehiro - - 2011
Red blood cells (RBC) of Alzheimer's disease (AD) patients are known to be in an excessively oxidized state (i.e., with a high accumulation of peroxidized phospholipids (PLOOH)). Previously we confirmed in vitro, in vivo murine, and in human studies that carotenoids can effectively inhibit accumulation of RBC PLOOH. Thus, the ...
Matsue Yuya - - 2011
BACKGROUND: Beta blockers were shown to prevent SCD in cardiomyopathy or coronary artery disease patients. Dialysis patients show elevated mortality rates, predominantly due to cardiovascular disease. SCD is now one of the leading causes of death in this population. However, the prevention of SCD remains to be elucidated. METHODS: We ...
Shahrzad Shahab - - 2011
BACKGROUND/OBJECTIVES: Sodium channel blockers are used to unmask the diagnostic ECG pattern of the Brugada syndrome (BrS) in case of a non-diagnostic baseline ECG. The aim of the study was to determine clinical and ECG predictors of a positive challenge test in patients suspected to the BrS. METHODS: A total ...
Frishman William H - - 2011
J Clin Hypertens (Greenwich). 2011;13:649-653. ©2011 Wiley Periodicals, Inc. KEY POINTS AND PRACTICAL RECOMMENDATIONS: •  β-Blockers are appropriate treatment for patients with hypertension and those who have concomitant ischemic heart disease, heart failure, obstructive cardiomyopathy, or certain arrhythmias. •  β-Blockers can be used in combination with other antihypertensive drugs to ...
Nagata T - - 2011
The authors have focused their attention to the radiological durability of cervical sagittal alignment after anterior cervical discectomy and fusion (ACDF) using autologous bone grafting. Among the patients who underwent ACDF with trans-unco-discal (TUD) approach between 1976 and 1997, 22 patients (16 males and 6 females) made return visits for ...
Desai Ravi V RV Division of Cardiology, Lehigh Valley Hospital, Allentown, PA 19103, United States. - - 2013
Right ventricular ejection fraction (RVEF) < 20% is an independent predictor of poor outcomes in patients with advanced chronic systolic heart failure (HF). The aim of this study was to examine if the adverse effect of abnormally reduced RVEF varies by the receipt of beta-blockers. In the Beta-Blocker Evaluation of ...
Shen Xuedong - - 2011
We investigated in 136 consecutive patients with heart failure receiving cardiac resynchronization therapy (CRT) the effect of carvedilol versus metoprolol CR/XL versus no beta blocker on mortality. Of the 136 patients, 42 (31%) were on carvedilol, 80 (59%) were on metoprolol CR/XL, and 14 (10%) were not on a beta ...
Müller-Wille R - - 2011
PURPOSE: This study was designed to determine the feasibility and efficacy of endovascular embolization with liquid embolic agent ethylene vinyl alcohol copolymer (Onyx) in patients with acute traumatic arterial bleeding. METHODS: This is a retrospective review of 13 patients (9 men and 4 women; mean age 45 years) with severe trauma ...
Manousou Pinelopi - - 2011
Introduction: Differentiation between steatosis and non-alcoholic steatohepatitis (NASH) in non-alcoholic fatty liver disease (NAFLD) is important as NASH progress to cirrhosis. No specific laboratory/imaging technique exists either to diagnose NASH or to select patients for liver biopsy. Patients and methods: We evaluated serum ferritin and the features of metabolic syndrome ...
Rimar Doron - - 2011
The purpose of this study is to characterize the chronic liver disease (CLD) that may be associated with familial Mediterranean fever (FMF). Twenty-seven patients (mean age, 48 ± 18 years; F/M, 16:11) with FMF who were referred for assessment of CLD were studied. Data regarding FMF and CLD were obtained from patient medical ...
Mookerjee Rajeshwar P - - 2011
The aim of this study was to systematically assess the diagnostic and prognostic value of early liver biopsy in patients who require hospital admission with acute deterioration of alcoholic cirrhosis. Sixty-eight patients with acute deterioration of alcoholic cirrhosis underwent a liver biopsy within 7 days and the biopsies were processed ...
Das S K - - 2011
Introduction: Readily available laboratory tests are extremely useful in achieving a better understanding of diseases, and thereby, allow thoughtful management decisions to be made. The examination of peripheral blood smears usually provides excellent clues to the cause of the disease. The main objective of this study was to compare the ...
Wong Vincent Wai-Sun - - 2011
Objective Non-alcoholic fatty liver disease (NAFLD) affects 20-40% of the general adult population. Due to shared risk factors, it is postulated that NAFLD patients have an increased risk of colorectal neoplasm and should be a target group for screening. The aim of this study was to examine the prevalence of ...
Bessembinders Kirsten - - 2011
Aims: This study was conducted to examine the relationship between triglyceride (TG) levels and a history of excessive drinking in patients with severe hypertriglyceridemia (HT). Methods: Alcohol intake as well as other risk factors associated with HT were searched for in case records of 300 patients known to the laboratory ...
Bob Petr - - 2011
Alcohol dependence during withdrawal and also in abstinent period in many cases is related to reduced inhibitory functions and kindling that may appear in the form of psychosensory symptoms similar to temporal lobe epilepsy frequently in conditions of normal EEG and without seizures. Because temporal lobe epileptic activity tend to ...
Mozos Ioana - - 2010
AIM: The aim of this study was to identify factors associated with prolonged QT interval in liver cirrhosis patients. MATERIALS AND METHODS: Thirty-eight patients with liver cirrhosis were enrolled in this study. The maximal QT interval (QTmax), heart rate-corrected QT interval (QTc), QT interval in lead DII (QTII), and mean ...
Sheldon Robert - - 2010
to develop evidence-based criteria that distinguish syncope due to ventricular tachycardia (VT) from vasovagal syncope (VVS) in patients with structural heart disease (SHD). one hundred and thirty-four patients with syncope and SHD completed a 118-item questionnaire and underwent noninvasive and invasive diagnostic assessments in a prospective cohort study. The contributions ...
Saeed Mohammad - - 2010
the PROVE trial was designed to determine if antitachycardia pacing (ATP) is clinically beneficial for primary prevention in patients who have implantable cardioverter defibrillators (ICDs) or cardiac resynchronization therapy defibrillators (CRT-Ds). use of ICDs and CRT-Ds reduces mortality in patients with ventricular dysfunction and mild to moderate heart failure. However, ...
Schaer Beat - - 2010
Current guidelines have indicated an implantable cardioverter-defibrillator (ICD) for patients with severe idiopathic dilated cardiomyopathy, for both primary and secondary prevention. Compared to coronary artery disease, the overall benefit has been smaller. A more refined risk assessment, using the left ventricular ejection fraction (LVEF) and prevention mode (primary/secondary), is still ...
Yener Oktay - - 2010
Background/aims: We aimed to evaluate the prevalence of non-alcoholic steatohepatitis and metabolic syndrome in patients with symptomatic gallstones undergoing laparoscopic or open cholecystectomy. Methods: A study of 95 patients was performed. Simultaneous liver biopsies were taken during cholecystectomy between 2006 and 2007. There were no postoperative complications. Patients with significant ...
Arya Arash - - 2010
Electrical storm due to recurrent ventricular tachycardia (VT) in patients with implantable cardioverter defibrillator (ICD) can adversely affect their long-term survival. This study evaluates the efficiency of the radiofrequency catheter ablation of electrical storm due to monomorphic VT in patients with idiopathic dilated cardiomyopathy (DCM) and assesses its long-term effects ...
Hossain Noreen - - 2011
Abstract Background. Both non-alcoholic steatohepatitis (NASH) and polycystic ovary syndrome (PCOS) are associated with metabolic syndrome (MS) and insulin resistance (IR). Except for a few case reports, there are no systematic assessments of NASH in PCOS patients. Aim. To determine the prevalence of NASH and independent factors associated with NASH ...
Polin Glenn M - - 2011
The risk and success of epicardial substrate ablation for ventricular tachycardia (VT) support the value of techniques identifying the epicardial substrate with endocardial mapping. The purpose of this study was to test the hypothesis that endocardial unipolar voltage mapping in patients with right ventricular (RV) VT and preserved endocardial bipolar ...
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