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Durmus Bekir - - 2012
Vitamin D has been found to have a role in the function of the immune system. There have been a lot of studies investigating a relation between vitamin D and disease activity in ankylosing spondylitis (AS). However, there have not been any studies arranging AS in groups according to vitamin ...
Sawicki Jakub - - 2012
Background:Vitiligo, the most common cutaneous depigmentation disorder, has reported associations with other autoimmune diseases. However, literature on the strengths of the associations is conflicting, and no data on the subject exist from a Canadian population.Objective:To determine autoimmune disease associations with vitiligo and which, if any, screening bloodwork is appropriate in ...
Koo Hyeon-Kyoung - - 2012
Vitamin D deficiency has been reported to be associated with the development of active tuberculosis (TB), but many discrepancies exist among studies. The aims of this study were to compare the frequency of vitamin D deficiency in a Korean population of TB patients and control subjects, and to monitor the ...
Larkin John - - 2012
Vitamin D deficiency is a common health complication in patients with chronic kidney disease and can be treated with an abundance of classical and advanced pharmaceutics. However, the impact of bundling in dialysis clinics limits the use of the most optimal therapeutics and desired efficacy targets in end-stage renal disease ...
Shirazi Kourosh M - - 2012
Patients with inflammatory bowel disease (IBD) are at high risk for low bone mineral density (BMD). This study aimed to evaluate BMD in IBD patients and its relationship with bone metabolism in a group of Iranian patients. A cross-sectional study was conducted on patients with IBD to assess BMD status ...
Bakker Sjoerd F - - 2012
BACKGROUND AND AIMS: Decreased bone mineral density (BMD) is common in Crohn's disease (CD) patients. This paper reports on the prevalence of decreased BMD in a referral cohort study of CD-patients next to the change of BMD over time in relation with CD-associated clinical characteristics. METHODS: 205 CD patients of ...
Neary Nicola M - - 2012
Pseudohypoparathyroidism type 1B (PHP1B) patients have PTH resistance at the renal proximal tubule and develop hypocalcemia and secondary hyperparathyroidism. Hyperparathyroid bone disease also develops in some patients. PHP1B patients are at theoretical risk of developing tertiary hyperparathyroidism. Patients were studied in a clinical research center. Five female PHP1B patients presented ...
Løken-Amsrud Kristin I - - 2012
OBJECTIVE:Studies based on deseasonalized vitamin D levels suggest that vitamin D may influence the disease activity in multiple sclerosis (MS), and high doses are suggested as add-on treatment to interferon-β (IFN-β). Seasonal fluctuation of vitamin D varies between individuals, thus the relationship to disease activity should preferentially be studied by ...
Eisner Brian H - - 2012
OBJECTIVE: To examine the relationship between serum 25-OH vitamin D and 24-hour urine calcium in patients with nephrolithiasis. METHODS: A retrospective review was performed. Patients evaluated in 2 metabolic stone clinics were included for analysis. Multivariate linear regression models were adjusted for known risk factors for stone disease (age, gender, ...
Riphagen Ineke J - - 2012
Abstract Objective: The mechanism of statin-related myopathy is unknown, while its prevalence is probably underestimated. An association between statin-related myopathy and vitamin D deficiency has been reported. In this pilot study we assessed the prevalence of myopathy in statin users attending to the outpatient clinic of the Department of Cardiology ...
Polić Melita Vuksić - - 2012
The aim of this study was to evaluate the possible association between polymorphisms in the Vitamin D receptor gene (VDR gene) and tendency for development of psoriasis vulgaris and diabetes mellitus in the population of Slavonia, which is a region in the Eastern Croatia. In order to conduct the mentioned ...
Romaní J - - 2012
Previous studies have shown increased prevalence of metabolic syndrome in patients with psoriasis. To characterize the anthropometric and metabolic profile of Spanish patients with moderate to severe psoriasis compared with controls without psoriasis matched for gender, age and body mass index (BMI), and to evaluate the impact of narrowband ultraviolet ...
Fillée Catherine - - 2012
BACKGROUND, OBJECTIVE: An international consensus conference underlined the importance of defining upper parathyroid hormone (PTH) reference values based on 25-OH-vitamin D [25(OH)D] to diagnose mild primary hyperparathyroidism. We determined the importance of this factor in a Belgian population. Intact PTH and 25(OH)D were measured in 261 healthy controls (18-65 years, ...
Taylor Susan C - - 2012
Knowledge regarding the determination, measurement, and supplementation of vitamin D in skin of color patients is evolving. At this time, it is believed that the majority of the skin of color population in the United States is vitamin D insufficient, which is particularly concerning given the possible links to disease ...
Mintzer Scott - - 2012
Enzyme-inducing antiepileptic drugs (AEDs) produce many alterations in metabolism, including vitamin levels. Whether they produce clinically relevant deficiency of B vitamins has rarely been assessed. We obtained B-vitamin levels in patients who were being converted from an inducing AED (phenytoin or carbamazepine) to a non-inducing AED (levetiracetam, lamotrigine, or topiramate), ...
Cranenburg Ellen C M - - 2012
Vitamin K is essential for the activity of γ-carboxyglutamate (Gla)-proteins including matrix Gla28 protein and osteocalcin; an inhibitor of vascular calcification and a bone matrix protein, respectively. Insufficient vitamin K intake leads to the production of non-carboxylated, inactive proteins and this could contribute to the high risk of vascular calcification ...
Krzyżanowska Patrycja - - 2012
BACKGROUND & AIMS: Available evidence suggests that patients with short bowel syndrome (SBS) might be at risk of vitamins A, D, E and B(1) deficiency. However, there is little clinical data describing the vitamin K status. Therefore, in the present study we aimed to assess the body resources of vitamin ...
Ertugrul Derun Taner - - 2012
Alopecia areata has been associated with many autoimmune diseases. There is a common belief that the prevalance of pernicious anemia is increased in patients with alopecia areata. In this study, we sought to investigate vitamin B12, folate and homocysteine metabolism in alopecia areata. We measured holotranscobalamine (holoTC), vitamin B12, folate ...
Shen Yu-Mei - - 2012
OBJECTIVE:: Fat-soluble vitamin deficiencies are common complications in pediatric patients with chronic cholestasis. The aim of this study was to evaluate the status of fat-soluble vitamin deficiencies in patients under current practice and to test the effect of an oral, absorbable, fat-soluble vitamin formulation (OAFSV) in these patients. METHODS:: We ...
Daroux Maïté - - 2012
Background: In patients with chronic kidney disease, vitamin D insufficiency is highly prevalent. It can be corrected by supplementation with either vitamin D2 or vitamin D3. Recent studies in patients without impaired kidney function suggest that vitamin D3 is more efficient than vitamin D2 in correcting vitamin D insufficiency. However, ...
Bee Carson - - 2012
OBJECTIVE:: To determine the incidence of Vitamin D deficiency in orthopaedic trauma patients undergoing fracture surgery living in the Northwest United States. DESIGN:: Retrospective observational cohort study. SETTING:: Level 2 trauma center in Eugene, Oregon. PATIENTS:: Two cohorts of patients undergoing fracture repair surgery during a three-month period in the ...
Klapdor S - - 2012
Exocrine pancreatic insufficiency due to chronic pancreatitis may result -depending on the degree of insufficiency-, in a decrease in serum 25-hydroxyvitamin D (25(OH)D) level. However, the data in the literature concerning the rate and extent of vitamin D deficiency in pancreatic cancer with or without previous pancreas resection, are very ...
Attar Suzan M - - 2012
To estimate the prevalence of low serum vitamin D level (25[OH]D) in patients with rheumatoid arthritis (RA) compared with healthy controls, and to analyze the association between 25(OH)D and disease activity. This retrospective analysis included 100 RA patients (85% women) and 100 controls, not on vitamin D supplements from January ...
Pipili Chrysoula - - 2012
This retrospective data analysis was undertaken to examine the biochemical differences between renal stone formers with normocalcemic hyperparathyroidism (NHPT) and those with normal parathyroid hormone (PTH) levels. Our goal was to ascertain whether 25-hydroxyvitamin D (25(OH)D) status related to PTH levels in this patient cohort. Our findings among 74 patients ...
Etemadifar Masoud - - 2012
The onset of multiple sclerosis in the majority of the cases occurs as a clinically isolated syndrome (CIS). We sought to assess serum levels of 25-hydroxyvitamin D (25-OHD) in CIS patients and healthy controls. In this cross-sectional study 40 patients (36 women and 4 men) with CIS manifesting as a ...
Fish Richard S - - 2012
The discovery of fibroblast growth factor-23 (FGF-23) as a key regulator of phosphate and vitamin D metabolism has forced a rethink about the mineral and bone disorder of chronic kidney disease (CKD). FGF-23 powerfully predicts adverse cardiovascular outcomes in patients with CKD and an important question is whether treatment regimens ...
Rusu Anca - - 2012
About 12-15 % of hemodialysis patients have a poor response to recombinant human erythropoietin (rHuEPO). The aim of this prospective study was to examine the influence of oxidative stress and vitamin E supplementation on rHuEPO responsiveness in chronic hemodialysis patients. Sixty-five hemodialysis patients treated with rHuEPO were studied. Those with iron ...
Petta Salvatore - - 2012
BACKGROUND: Genotype 1 (G1) chronic hepatitis C (CHC) patients achieving a rapid virological response (RVR) on pegylated interferon (PEG-IFN) plus ribavirin have a high chance of sustained virological response (SVR), influenced by IL28B status, viral load, fibrosis and insulin resistance. We assessed whether 25-hydroxyvitamin D (25[OH]D) serum levels are linked ...
Lee So-Young - - 2012
Background/Aims: The role of vitamin D in the process of vascular calcification is unclear in patients with chronic kidney disease. We investigated whether serum 25-hydroxyvitamin D [25(OH)D] is associated with vascular calcification in predialysis and dialysis patients. Methods: We included 86 predialysis and 139 dialysis patients. The simple vascular calcification ...
Olea J L - - 2012
OBJECTIVE: To assess the characteristics of patients with wet AMD and low intake of lutein and zeaxanthin in our population. METHODS: A prospective, observational, cross-sectional study was conducted on patients with active wet AMD. A full blood count, a lipid and liver profile, a dietary interview (24-hour recall), and an ...
Reid Suzanne M - - 2012
Low vitamin D levels have been associated with adverse effects on health. The primary source of vitamin D is cutaneous production during sunlight exposure. Sun avoidance can restrict vitamin D photosynthesis and is common practice amongst patients with photosensitivity. Few studies have examined vitamin D status in this population, particularly ...
Ogawa Tetsuya - - 2012
Vitamin D deficiency is common in hemodialysis (HD) patients. The aim of this study was to determine whether HD patients with low 25-hydroxyvitamin D [25(OH)D] levels are at increased risk of mortality. This was a prospective cohort study of Japanese HD patients. We selected all patients with measured serum 25(OH)D ...
Mądry Edyta - - 2012
As decreased bone mineral density (BMD) is a common problem in cystic fibrosis (CF) and milk products may have pivotal dietary role affecting BMD, we aimed to assess the potential influence of adult-type hypolactasia (ATH) and lactose malabsorption (LM) on BMD in adolescent and young adult patients. In 95 CF ...
Ferreira Iahel Manon de Lima - - 2012
BACKGROUND: An alternative form of nutrition therapy for patients with short bowel syndrome (SBS) who do not have home parenteral nutrition (PN) available is the administration of the PN cycle during regular hospital admissions and oral vitamin supplement at home. The aim of this study was to evaluate serum levels ...
Han Jiangli - - 2012
Thromboembolism is the crucial cause of ischemic stroke in patients with atrial fibrillation (AF). Anticoagulation therapy with vitamin K antagonists, such as warfarin, have been proven to be effective for stroke prevention in AF. Nonetheless, the use of warfarin may be limited due to increased risk of bleeding, the potential ...
Suarez Jorge - - 2012
We sought to characterize patient factors and regional variations associated with vitamin K antagonist (VKA) use in patients with heart failure (HF) and atrial fibrillation (AF) in areas outside the United States and Europe. The ADHERE-International registry enrolled patients with decompensated HF from 10 Asia Pacific and Latin American countries ...
Stoll D - - 2012
We evaluated the effectiveness of supplementation with high dose of oral vitamin D3 to correct vitamin D insufficiency. We have shown that one or two oral bolus of 300,000 IU of vitamin D3 can correct vitamin D insufficiency in 50% of patients and that the patients who benefited more from supplementation ...
Gauchan Dron - - 2012
In patients with myeloproliferative disorders, normal to high serum vitamin B(12) concentrations have often been reported. The primary objective of this study was to determine whether normal or elevated serum vitamin B(12) levels in myeloproliferative disorders might actually mask the true underlying vitamin B(12) deficiency in some patients. Thirty-three patients ...
Borras Mercè - - 2012
BACKGROUND: Telomeres are special chromatin sequences located at the end of eukaryotic chromosomes, protecting these regions from recombination and degradation. Previous studies have reported a decrease in telomere length on white blood cells from hemodialysis (HD) patients, which suggests premature senescence. Active vitamin D treatment has been reported to have ...
Zhang Kunying - - 2012
SUMMARY AT A GLANCE: The authors designed a cross-sectional study to investigate plasma vitamin C level in patients with HD and PD (total 382 patients). The results showed that 35.9% patients had severe vitamin C deficiency (<2µg/ml). Vitamin C deficiency was associated with HD. Thus, they concluded that vitamin C ...
Orgaz-Molina Jacinto - - 2012
Some autoimmune conditions have been associated with reduced vitamin D levels, including systemic lupus erythematosus, rheumatoid arthritis, diabetes mellitus, and multiple sclerosis. The main objective of this study was to analyze the 25-hydroxyvitamin D (OHD) status of patients with psoriasis in comparison with control subjects without this disease. This case-control ...
Bansal Beena - - 2012
Vitamin D [(25(OH)D] deficiency and insufficiency is common in patients with chronic kidney disease (CKD). 25(OH)D has been found to have beneficial effects on bone, cardiovascular and immune functions. There are little data about vitamin D levels in Indian patients on dialysis. This study was undertaken to determine the vitamin ...
Shea M Kyla MK Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem NC, USA. - - 2012
Vascular calcification occurs when calcium accumulates in the intima (associated with atherosclerosis) and/or media layers of the vessel wall. Coronary artery calcification (CAC) reflects the calcium burden within the intima and media of the coronary arteries. In population-based studies, CAC independently predicts cardiovascular disease (CVD) and mortality. A preventive role ...
Milovanovic Milena - - 2012
BACKGROUND: Recent studies revealed a strong association between vitamin D (VD) status and chronic heart failure (CHF). It is now commonly considered that proinflammatory immune response underlies CHF development. OBJECTIVE: Since VD expresses anti-inflammatory properties, we investigated its impact on cytokines implicated in CHF, such as TNFα and IL-17, in ...
Bochyńska Anna A I(st) Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland. - - 2012
To investigate the influence of vitamin B supplementation on the plasma total homocysteine (p-tHcy), serum folate (s-FA), serum B12 (s-B12), and clinical state of patients with chronic epilepsy. Beck Depression Inventory (BDI) scores and p-tHcy, s-B12, and s-FA levels were assessed at baseline, after 1 year of supplementation (G1), and ...
Becker-Cohen Rachel - - 2012
BACKGROUND: Three patients with Dent's disease presented with complaints of impaired night vision or xerophthalmia and were found to have severely decreased serum retinol concentrations. Retinol, bound to its carrier retinol-binding protein (RBP), is filtered at the glomerulus and reabsorbed at the proximal tubule. We hypothesized that urinary loss of ...
Eller Andrew W - - 2012
To report the first described cases of peripheral yellow corneal rings secondary to vitamin supplementation for age-related macular degeneration (ARMD). Retrospective single-center case series. The eyes of 4 patients taking vitamin supplementation for ARMD were examined at the University of Pittsburgh Medical Center Department of Ophthalmology between January 2010 and ...
Toyoda Hidenori - - 2012
Des-gamma-carboxy prothrombin (DCP) is a useful tumor marker for hepatocellular carcinoma (HCC), but its utility was limited in patients taking vitamin K antagonists. We evaluated the newly developed method to measure serum DCP, (NX-DCP ratio) for its ability to identify DCP elevation induced by HCC in this patient subpopulation. Conventional ...
Olama Shereem Mohamed - - 2012
Patients with fibromyalgia syndrome (FMS) have impaired mobility and therefore get less sunlight exposure, we postulated that they may be at increased risk of developing osteoporosis (OP). The aim of this study was to assess and compare serum vitamin D level and bone mineral density (BMD) value in patients with ...
Gotsman Israel - - 2012
AIMS: Vitamin D deficiency is a highly prevalent, global phenomenon. The prevalence in heart failure (HF) patients and its effect on outcome are less clear. We evaluated vitamin D levels and vitamin D supplementation in patients with HF and its effect on mortality. METHODS AND RESULTS: 25-Hydroxyvitamin D [25(OH)D] levels ...
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