Search Results
Results 351 - 400 of 2077
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Lindblom A - - 2009
The authors describe a case of a 38-year-old male with minor stroke due to exacerbation of hereditary deficiency of ADAMTS 13 resulting in a chronic relapsing form of thrombotic thrombocytopenic purpura (TTP). The clue to the unusual pathogenesis was given by laboratory findings of a mild anaemia and thrombocytopenia. After ...
Grunwald I Q - - 2009
BACKGROUND AND PURPOSE: This is the first single center experience illustrating the effectiveness of the penumbra system (PS) in the treatment of large vessel occlusive disease in the arena of acute ischaemic stroke. The PS is an innovative mechanical thrombectomy device, employed in the revascularization of large cerebral vessel occlusions ...
Kim Jong S - - 2009
BACKGROUND AND PURPOSE: Clinical-imaging correlation and long-term clinical outcomes remain to be investigated in medial medullary infarction (MMI). METHODS: We studied clinical, MRI, and angiographic data of 86 consecutive MMI patients. The lesions were correlated with clinical findings, and long-term outcomes, divided into mild and severe (modified Rankin scale >3), ...
Hussein Ayman A - - 2009
BACKGROUND: The best periprocedural anticoagulation strategy at the time of pulmonary vein isolation (PVI) is not known. Most centers stop administering warfarin (Coumadin) and use bridging with heparin or enoxaparin. OBJECTIVE: The purpose of this study was to evaluate the efficacy and safety of PVI under therapeutic international normalized ratio ...
- - 2009
BACKGROUND AND PURPOSE: The purpose of this clinical evaluation was to assess the safety and effectiveness of the Penumbra System in the revascularization of patients presenting with acute ischemic stroke secondary to intracranial large vessel occlusive disease. METHODS: In this prospective, multicenter, single-arm study, 125 patients with neurological deficits as ...
Emam Abdelhady Taha - - 2009
BACKGROUND AND PURPOSE: Stroke has been increasingly recognized in children in recent years, but diagnosis and management can be difficult because of the diversity of underlying risk factors, atypical presentation and the absence of a uniform treatment approach. The aim of this study was to examine risk factors, clinical presentation, ...
Aries M J H - - 2009
BACKGROUND: The presence of a hyperdense middle cerebral artery sign (HMCAS) on baseline brain CT is associated with poor clinical outcome in stroke patients treated with intravenous recombinant tissue plasminogen activator (tPA). It remains uncertain whether the presence of HMCAS is associated with acute neurological deterioration after tPA treatment. OBJECTIVE: ...
Jaleel Anila - - 2009
To investigate whether hypo-adiponectinemia is present in ischemic stroke patients. This comparative study was carried out in the Biochemistry Department, Ziauddin University, Karachi, Pakistan in 2008. In this study, plasma adiponectin concentration was measured by an enzyme-linked immunosorbent assay in subjects with and without ischemic cerebrovascular disease (CVD). A total ...
Abe Hiroaki - - 2009
Stroke is the leading cause of long-term disability, and many stroke patients have hemiparesis. Hemiparesis induces ankle-control disturbances and equinovarus deformity, leading to difficulty in walking and an increased risk for falling. Plastic ankle-foot orthosis (PAFO) is frequently prescribed to correct ankle joint alignment and increase walking speed and stride ...
Mishra M N - - 2009
BACKGROUND: Stroke may be caused by antiphospholipid antibodies (APL), especially in young persons without other risk factors. AIM: The aim of this study was to determine the prevalence of two clinically significant APL-anticardiolipin antibody (ACL) and lupus anticoagulants (LA) in young patients presenting with sudden neurological deficit. SETTINGS AND DESIGN: ...
Linares Guillermo - - 2009
Hypothermia is considered nature's "gold standard" for neuroprotection, and its efficacy for improving outcome in patients with hypoxic-ischemic brain injury as a result of cardiac arrest is well-established. Hypothermia reduces brain edema and intracranial pressure in patients with traumatic brain injury. By contrast, only a few small pilot studies have ...
De Silva Deidre Anne - - 2009
Family history is a known non-modifiable risk factor of stroke. We aimed to compare the frequency of a family history of vascular disease between ethnic South Asian and Chinese stroke patients. We studied consecutive ethnic South Asian and Chinese ischaemic stroke patients matched for age, gender and presence of diabetes. ...
Naess Halvor - - 2009
BACKGROUND: The aim of this study was to evaluate characteristics and long-term outcome of young patients with ischemic stroke (15-49 years at stroke onset) and aphasia. METHODS: Aphasia was defined as less than 10 points in the speech subscale of the Scandinavian Stroke Scale on long-term follow-up. Risk factors, origin, ...
Gonzalez-Gay Miguel A - - 2009
Patients with giant cell arteritis (GCA) generally present with cranial ischemic manifestations that are directly related to vascular involvement. They may also experience strokes in the territory of the carotid or the vertebrobasilar artery. We conducted the current study to assess the frequency and predictors of strokes in general, and ...
Handke Michael - - 2009
A patent foramen ovale (PFO) enables a right-to-left shunt in about a quarter of the population. The marked association between cryptogenic stroke and PFO supports the hypothesis that paradoxical embolism could be a relevant cause of stroke. Although this association has been described in several studies for patients <55 years ...
Komotar Ricardo J - - 2009
Recent evidence has shown that after the initial occlusion, a large portion of stroke patients achieve some degree of reperfusion either through collateral circulation or clot dissolution. However, it appears that this reperfusion may lead to increased inflammation-induced damage. Even though the exact mechanism of this secondary injury is unclear, ...
Chabriat Hugues H Service de Neurologie, Groupe Hospitalier Lariboisière-Fernand-Widal, Assistance Publique Hôpitaux de Paris, F-75010, Paris, - - 2009
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is the most common heritable cause of stroke and vascular dementia in adults. Clinical and neuroimaging features resemble those of sporadic small-artery disease, although patients with CADASIL have an earlier age at onset of stroke events, an increased frequency of ...
Niu Ko-Chi - - 2009
Here in we report the case of a patient who displayed a classic heat stroke with multiple organ dysfunction and hypercoagulable state resistant to conventional whole body cooling and antipyretic therapy, and necessitating the use of hyperbaric oxygen therapy (HBOT) to rescue him from death. A 49-year-old male laborer, suffering ...
Kimura Kazumi - - 2009
BACKGROUND AND PURPOSE: In acute stroke patients treated with intravenous tissue plasminogen activator (t-PA), early recanalization of occluded arteries can improve the clinical outcome. The magnetic susceptibility effect of deoxygenated hemoglobin in red thrombi can present as hypointense signals on T2*-weighted gradient echo imaging. We investigated whether the gradient echo ...
Asimos Andrew W - - 2010
STUDY OBJECTIVE: We evaluate, in admitted patients with transient ischemic attack, the accuracy of the ABCD(2) (age [A], blood pressure [B], clinical features [weakness/speech disturbance] [C], transient ischemic attack duration [D], and diabetes history [D]) score in predicting ischemic stroke within 7 days. METHODS: At 16 North Carolina hospitals, we ...
Tang W K - - 2009
OBJECTIVE: The clinical significance of microbleeds (MBs) in the development of psychiatric conditions following a stroke is unknown. Lesions located in various cortical and subcortical areas are thought to be involved in the pathophysiology of post-stroke emotional lability (PSEL). This study examined the association between PSEL and MBs. METHODS: A ...
Rowe F - - 2010
To evaluate the profile of strabismus that occurs in stroke survivors and determine the relationship between site of stroke and symptom of diplopia. Prospective multi-centre cohort trial involving 16 recruiting centres (Vision In Stroke (VIS) Group). Standardised referral and investigation protocol used by local investigators. Each patient underwent assessment of ...
Kotsaftis Panagiotis - - 2010
The aim of this study is to identify the main cardiovascular risk factors (CRFs) in patients over 65 years with ischemic stroke. This is a retrospective study in 175 patients that were hospitalized in our department due to ischemic stroke in the period 2006-2007. The patients were divided in two ...
Cho Kyung-Hee - - 2009
It remains unknown whether subacute lesion volume increase is related to neurologic progression (NP) and clinical outcome (CO) in patients with single subcortical infarct (SSI) in the middle cerebral artery (MCA) territory. We studied 77 patients who underwent diffusion-weighted MRI (DWI) within 48 h after stroke onset, which revealed unilateral ...
Romero Jos? R - - 2009
BACKGROUND AND PURPOSE: Detection of an intracardiac shunt is frequently sought during the evaluation of patients with cryptogenic ischemic stroke and agitated saline intravenous injection, or "bubble study" (BS), is performed in most cases. We present the first attempt to identify the clinical features in patients who had cerebral ischemic ...
Jacobs Laurie G - - 2009
BACKGROUND: Anticoagulation for stroke prevention is underused in elderly patients with nonvalvular atrial fibrillation (AF). Those with falls and/or early dementia may be at particular risk for stroke and hemorrhage. OBJECTIVE: The aim of this study was to determine the prescribing patterns, risks, and benefits of anticoagulation with warfarin or ...
Abdullah W Z - - 2009
INTRODUCTION: The fibrinolytic system plays an important role in normal haemostasis and endothelial function. This study was conducted to compare three fibrinolytic markers, i.e. plasminogen, tissue-plasminogen activator (t-PA) and plasminogen activator inhibitor type-1 (PAI-1) between acute stroke and stable non-stroke patients and to investigate the clinical significance of these markers. ...
Kong K-H - - 2009
BACKGROUND: Studies have shown that deep vein thrombosis (DVT) is common after an acute stroke. Less common are studies documenting DVT in stroke patients admitted to rehabilitation. The purpose of this study was to determine the frequency and risk factors of DVT in stroke patients admitted to a rehabilitation unit ...
Kim Eun-Joo - - 2009
BACKGROUND: Patients with neglect often repeatedly cancel the same targets, a form of motor perseveration (MP). There seems to be 2 types of MP, making uninterrupted multiple strokes for each target, consecutive MP (CMP) or return MP (RMP) where patients return to previously canceled targets and remark them. OBJECTIVE: The ...
Lindley Richard I RI Western Clinical School, University of Sydney, Sydney, NSW 2006, Australia. - - 2009
Lacunar stroke accounts for a quarter of cases of acute ischaemic stroke; however, its underlying pathophysiology remains unclear. Our aim was to establish whether there is an association between changes in the retinal microvasculature and lacunar stroke that might provide clues to the pathology of cerebral small vessel disease. In ...
He Lanying - - 2010
OBJECTIVE: To investigate the difference of heart rate variability (HRV) and serum creatine kinase isoenzyme (CK-MB) activity between right-sided and left-sided stroke, and the relative impact of cardiac autonomic imbalance and heart abnormality on death by serum CK-MB activity and fractal dimension (FD) detection in patients with stroke. METHODS: Three ...
Feurer R - - 2009
BACKGROUND AND PURPOSE: Despite numerous studies, the role of patent foramen ovale (PFO) as a risk factor for stroke due to paradoxical embolism is still controversial. On the assumption that specific lesion patterns, in particular multiple acute ischaemic lesions on diffusion-weighted magnetic resonance imaging, indicate a cardioembolic origin, we compared ...
Alexandrov Andrei V - - 2009
BACKGROUND AND PURPOSE: Early deterioration can occur after acute stroke for a variety of reasons. We describe a hemodynamic steal and associated neurological deterioration, the reversed Robin Hood syndrome (RRHS). We aimed to investigate the frequency and factors associated with RRHS. METHODS: Consecutive patients with acute cerebral ischemia underwent serial ...
Belv?s Robert - - 2009
OBJECTIVE: Patent foramen ovale (PFO) has been related to stroke but its existence has not been explained to date. NKX2-5 is the most implicated gene in fetal atrial septation. We studied NKX2-5 with respect to the presence or absence of PFO in stroke patients. METHODS: A prospective analysis of NKX2-5 ...
Gawarammana I - - 2009
Bites due to Russell's Viper (Daboia russelii) are common in Sri Lanka. Commonest haematological manifestation is consumptive coagulopathy and bleeding. Commonest neurological manifestations are ptosis, ophthalmoplegia and rarely respiratory failure which are due to presynaptic inhibition of neuromuscular transmission. There are no authenticated reports of acute ischemic strokes following bites ...
Doubal F N - - 2009
Lacunar stroke is common, but the etiology of the small vessel abnormality is unknown. Retinal vessels share ontogeny, size, and physiologic characteristics with cerebral small vessels, and retinopathy is associated with stroke. We compared retinal microvessel appearance as a surrogate for cerebral small vessels in patients with lacunar and large ...
Alsheikh-Ali Alawi A AA Institute for Clinical Research and Health Policy Studies, Division of Cardiology, Department of Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, - - 2009
Patent foramen ovale (PFO) is significantly associated with cryptogenic stroke (CS). However, even in patients with CS, a PFO can be an incidental finding. We sought to estimate the probability that a PFO in a patient with CS is incidental. A systematic search identified 23 case-control studies examining the prevalence ...
Shin Yong-Il - - 2010
OBJECTIVE AND IMPORTANCE: Recent works on extradural cortical stimulation have been successful in improving neurological recovery in chronic stroke patients. On the other hand, single perirolandic stimulations are often associated with disappointing results. CLINICAL PRESENTATION: We report two cases of chronic stroke in which the magnitude of infarct was too ...
Huang Ya-Ling - - 2009
Hyoid-larynx approximation is an essential part of the swallowing process, and is related to airway protection. We aimed to evaluate the reliability of ultrasonographic examination of hyoid-larynx approximation and measure the approximation in stroke patients with or without dysphagia. Fifteen normal subjects and 40 stroke patients with or without dysphagia ...
Van Dijck Gert - - 2009
OBJECTIVE: Assessing recovery after stroke has been so far a time consuming procedure in which trained clinicians are required. A demand for automated assessment techniques arises due to the increasing number of patients with stroke and the continuous growth of new treatment options. In this study, we investigate the applicability ...
Zito Concetta - - 2009
OBJECTIVE: The aim of this study was to compare transthoracic echocardiography (TTE) and transcranial Doppler ultrasonography (TCD) with transesophageal echocardiography (TEE) in order to define the best clinical approach to patent foramen ovale (PFO) detection. METHODS: In total, 72 consecutive patients (33 men) with a mean age of 49 +/- ...
Ma Li - - 2009
OBJECTIVE: We investigated whether baseline vessel status evaluated by magnetic resonance angiography (MRA) can be the foremost factor to classify acute ischemic stroke patients into subgroups for thrombolytic therapy within 3-6 hours of symptom onset. METHODS: Acute ischemic stroke patients beyond 3 hours after symptom onset were examined by stroke ...
Pong Ya-Ping - - 2009
PURPOSE: To examine the hemiplegic shoulders for soft-tissue injury by musculoskeletal sonography and to determine the relationship between the motor functions of the upper extremity and these injuries, which play an important role in hemiplegic shoulder pain and may impede rehabilitation. METHODS: The following characteristics of 34 acute stroke patients ...
Elijovich Lucas - - 2009
INTRODUCTION: Despite extensive inpatient workup including telemetry monitoring, a significant proportion of stroke is classified as cryptogenic at hospital discharge. It is possible that a significant proportion of cryptogenic stroke is a result of intermittent atrial fibrillation (AF). Thirty-day cardiac event monitors (30-DEM) may increase the rate of AF detection ...
Ebinger Martin - - 2009
BACKGROUND AND PURPOSE: The clinical-diffusion mismatch (CDM) model has been proposed as a simpler tool than perfusion-diffusion mismatch (PDM) to select acute ischemic stroke patients for thrombolytic therapy. We hypothesized that in the 3- to 6-hour time window, the effect of tPA was significantly greater in patients with CDM than ...
Toyoda Kazunori - - 2009
BACKGROUND AND PURPOSE: The purpose of this study was to determine at which time points acute blood pressure (BP) was associated with neurological deterioration at 3 weeks in patients with ischemic stroke as a whole and in patients with different subtypes. METHODS: BP was measured every 6 hours for the ...
Martínez-García Miguel Angel - - 2009
RATIONALE: Obstructive sleep apnea (OSA) is an independent risk factor for stroke, but little is known about the role of continuous positive airway pressure (CPAP) on mortality in patients with stroke. OBJECTIVES: To analyze the independent impact of long-term CPAP treatment on mortality in patients with ischemic stroke. METHODS: Prospective ...
Hur Jin - - 2009
BACKGROUND AND PURPOSE: We assessed the diagnostic performance of 2-phase 64-slice cardiac computed tomographic angiography (CCTA) for the detection of a cardiac source of embolism in stroke patients using transesophageal echocardiography (TEE) as the reference standard. METHODS: We selected 137 patients who had experienced a recent episode of stroke and ...
Peters Nils - - 2009
Cortical ischemic stroke affecting the precentral "hand knob" area is a rare but well known stroke entity. To date, little is known about the underlying stroke mechanisms and the prognosis. Twenty-nine patients admitted to our service between 2003 and 2007 were included in the study on the basis of an ...
Mizuike Chihiro - - 2009
The purpose of this study was to describe the characteristics of stroke patient gait using the acceleration signals which were obtained during walking. Sixty-three stroke hemiplegic patients and 21 age-matched healthy elderly individuals took part in this study. A wireless tri-axial accelerometer, fixed to a belt at the level of ...
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