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Results 301 - 350 of 2118
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Uemura Jyunichi - - 2010
The aim of the present study was to investigate the frequency of having occult malignancy in patients with acute ischemic stroke and their clinical characteristics. We retrospectively enrolled 1,714 consecutive ischemic stroke patients within 7 days of onset. The patients were divided into two groups: the Non-M group had no ...
Holzer Katrin - - 2010
BACKGROUND: Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA. We assessed the value of this score to predict the vascular outcome after TIA during medium- to long-term follow-up. METHODS: The ABCD2 score of 176 ...
Molnar Tihamer - - 2010
The purpose of this study was to determine the relationship between high-sensitive C-reactive protein (hsCRP) and leukocyte antisedimentation rate (LAR) as a specific test to detect early activation of leukocytes providing the first line of defence against infections in ischemic stroke. In 49 patients with acute ischemic events and 61 ...
Su Winnie S - - 2010
Objectives. The primary objective of this study was to determine the relationship between waist-to-hip ratio (WHR), cardiovascular (CV) events, and mortality in peritoneal dialysis (PD) patients. A secondary objective was to investigate the association between abdominal obesity and systemic inflammatory markers. Methods. This is a prospective study of 22 prevalent ...
Sagen Ulrike - - 2010
BACKGROUND: Previous factor analyses of the Apathy Evaluation Scale (AES) have indicated the presence of one main factor comprising core symptoms of apathy. However, the factor structure of the AES has not been determined in patient samples with cerebrovascular disorders. Aims of the study were to 1) examine the factor ...
Garg Nadish - - 2010
Warfarin has been the cornerstone therapy for stroke prevention in non-valvular atrial fibrillation (NVAF), particularly in patients at high risk of ischemic stroke or thromboembolism. Warfarin use in NVAF results in a 64% relative reduction in the incidence of ischemic stroke and several trials have demonstrated warfarin to be superior ...
González R Gilberto - - 2010
BACKGROUND: The stability of hypoperfused brain tissue in stroke patients with major artery occlusions is unknown. The purpose of this study was to determine the persistence of a diffusion/perfusion mismatch in patients with ICA or proximal MCA occlusions. METHODS: Fourteen patients with ICA and/or proximal MCA occlusion and a diffusion/perfusion ...
Roffe Christine - - 2010
BACKGROUND: Mild hypoxia is common in patients with stroke, and associated with worse long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no benefit after acute stroke, but did not report compliance and the effect on oxygenation. The aim of this ...
Gall Carolin - - 2010
To evaluate vision-related and health-related quality of life (VRQoL, HRQoL) in first stroke patients with homonymous visual field defects (VFD) with respect to the extent of the lesion. Since VFD occur in approximately 10% of stroke patients the main purpose of the study was to investigate the additional impact of ...
Huisa Branko N - - 2010
Statin therapy in patients with cardiovascular disease is associated with reduced incidence of stroke. The Stroke Prevention by Aggressive Reduction of Cholesterol Levels (SPARCL) trial showed daily treatment with 80 mg of atorvastatin in patients with a recent stroke or transient ischemic attack (TIA) reduced the incidence of fatal or ...
Prange Gerdienke B - - 2010
In many stroke patients arm function is limited, which can be related to an abnormal coupling between shoulder and elbow joints. The extent to which this can be translated to activities of daily life (ADL), in terms of muscle activation during ADL-like movements, is rather unknown. Therefore, the present study ...
Migliaccio-Walle Kristen - - 2010
Peripheral arterial disease (PAD) is caused by narrowing of the arteries in the lower extremities. Limited data exist concerning the impact of diffuse vascular disease (DVD) on prognosis and costs. Thus, the objective of this study is to estimate the impact of DVD on morbidity, mortality and costs. PAD was ...
Idicula Titto T - - 2010
The prevalence of microembolic signals (MES) during the acute phase of ischemic stroke and its influence on outcome is not well studied. The aim of our study was to determine the prevalence of MES, the different factors that are associated with the presence of MES and the association between MES ...
Engel-Nitz Nicole M - - 2010
To evaluate the clinical outcomes and incremental health care costs of ischemic stroke in a US managed care population. A retrospective cohort analysis was done on patients (aged 18+ years) hospitalized with noncardioembolic ischemic stroke from January 1, 2002, through December 31, 2003, identified from commercial health plan administrative claims. ...
Beer Christopher D - - 2010
Acute ischaemic stroke is associated with alteration in systemic markers of vascular function. We measured forearm vascular function (using forearm flow mediated dilatation) to clarify whether recent acute ischaemic stroke/TIA is associated with impaired systemic vascular function. Prospective case control study enrolling 17 patients with recent acute ischaemic stroke/TIA and ...
Hannerz Harald - - 2010
Successful return to work is regarded as one of the most important outcome factors for working-age post stroke patients. The present study will estimate the effect of various predictors on the odds of returning to work after stroke. Nearly twenty thousand 20-57 year-old stroke patients in Denmark who were gainfully ...
Naghdi Soofia S Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran. - - 2010
To determine the extent to which the Brunnstrom recovery stages of upper limb in hemiparetic stroke patients are correlated to neurophysiological measures and the spasticity measure of Modified Modified Ashworth Scale (MMAS). A concurrent criterion-related validity study. Not applicable. Thirty patients (15 men and 15 women; mean ± SD = ...
Santamato Andrea A Department of Physical Medicine and Rehabilitation-'OORR Hospital', University of Foggia, Italy. - - 2010
In rehabilitation settings, motor imagery, motor observation and mirror therapy serve as techniques for the recovery of paretic upper limb in patients with movement disorders after stroke, whereas botulinum toxin type A (BTX-A) offers the best treatment for focal spasticity. After haemorrhagic stroke, three patients (two men and one woman, ...
Meseguer Elena - - 2010
BACKGROUND AND PURPOSE: The purpose of this study was to assess the prevalence of embolic signals (ES) in acute coronary syndromes (ACS) and their association with stroke. METHODS: From December 2004 to October 2006, 209 consecutive patients with ACS (without prosthetic heart valves or previous stroke) were studied within 72 ...
Lima F O FO Department of Neurology, Stroke Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. - - 2010
Concerns have recently grown regarding the safety of iodinated contrast agents used for CTA and CTP imaging. We tested whether the incidence of AN, defined by a >or=25% increase in the post-contrast scan creatinine level, was higher among patients with ischemic stroke who underwent a functional contrast-enhanced CT protocol compared ...
Marousi S - - 2010
Past ischemic stroke (IS) patients display suppressed adiponectin (ADPN) levels a few months after disease onset. It is still unclear whether hypoadiponectinemia is already present by the early stages of stroke or occurs as a delayed effect of the acute ischemic reaction. In the present study we investigated ADPN levels ...
Ding Ding - - 2010
BACKGROUND/AIMS: To measure the risk of vascular event occurrence among postischemic stroke patients in mainland China. METHODS: In this multicenter prospective stroke registry study, we enrolled 1,951 patients diagnosed with acute ischemic stroke. Demographic data, prestroke risk factors, severity of neurological deficits and disability graded on the National Institutes of ...
Barr Taura L - - 2010
Matrix metalloproteinases (MMP) may play a role in blood-brain barrier (BBB) disruption after ischemic stroke. We hypothesized that plasma concentrations of MMP-9 are associated with a marker of BBB disruption in patients evaluated for acute stroke. Patients underwent MRI on presentation and approximately 24 hours later. The MRI marker, termed ...
Wang Yi-Dong - - 2010
BACKGROUND/AIMS: Between 50 and 70% of stroke survivors suffer from severe disabilities such as paralysis and aphasia. Poor stroke outcome is a reflection of our incomplete understanding of the underlying mechanisms, and hence the capacity to implement appropriate treatment(s). We evaluated hypoxic tissue after stroke and patient condition severity and ...
Bernard Timothy J - - 2010
OBJECTIVE: To test the hypothesis that acute elevations of biomarkers of hypercoagulability and inflammation are common in children with arterial ischemic stroke (AIS), particularly among etiologic subtypes that carry an increased risk of recurrent stroke. STUDY DESIGN: In this prospective/retrospective institutional-based cohort study of acute childhood-onset AIS (n = 50) ...
Nishiyama Yasuhiro - - 2010
BACKGROUND: Aspiration pneumonia is one of the most important complications following ischaemic stroke, and a leading cause of mortality in stroke patients. This is particularly prevalent in patients with involvement of the basal ganglia, which may be due to impaired neurotransmission through lack of production of substance P. METHODS: Consecutive ...
Topakian Raffi - - 2010
BACKGROUND: After acute ischaemic stroke (AIS) or transient ischaemic attack (TIA), the detection of peripheral arterial disease (PAD) as a marker of generalized atherosclerosis may improve the risk stratification and prevention of future atherothrombotic events. We aimed to determine the prevalence of PAD indicated by an ankle-brachial index (ABI) of ...
Seki Yukio - - 2010
The pathophysiology underlying the high incidence of post-stroke infectious complications has not been fully understood. We measured the respiratory burst of neutrophils as an index of their bactericidal function in patients with haemorrhagic stroke, and we also measured the plasma concentrations of noradrenalin, cortisol and neutrophil function-related amino acids. Blood ...
Nonnekes Jorik H JH UCL Institute of Neurology, London, United Kingdom, Radboud University, Nijmegen, The - - 2010
The ability to make step adjustments while walking is often impaired following a stroke, but the basic sensorimotor control deficits responsible have not been established. To identify these deficits in Patients who have recovered from stroke leaving only mild lower limb impairment. Ten stroke and 10 age-matched control patients stepped ...
Cho Hyun-Ji - - 2010
BACKGROUND: Transoesophageal echocardiography (TOE) is the gold standard for detecting potential cardiac sources of embolism (PCSE). However, the role of TOE in patients with ischaemic stroke with normal sinus rhythm (NSR) and no cardiac disease remains uncertain. METHODS: The authors retrospectively analysed 1833 consecutive patients with ischaemic stroke with NSR ...
Jannink Michiel J A - - 2009
One of the neuropsychological deficits that can result from a stroke is the neglect phenomenon. Neglect has traditionally been assessed with paper-and-pencil tasks, which are administered within the reaching space of a person. The purpose of this explorative study is to investigate whether it is possible to assess neglect in ...
Bonnin-Vilaplana Marc - - 2009
The purpose was to examine the occurrence of sleep-related breathing disorders (SRBD) and variables related to SRBD in patients with acute lacunar stroke. In 68 consecutive patients with radiologically proven lacunes, respiratory polygraphy within the first 48 h of stroke onset was performed. SRBDs were classified according to mutually exclusive ...
Sato Shoichiro - - 2010
BACKGROUND: Intracranial arterial lesions are important causes of ischemic stroke, particularly in the Asian population. Of the intracranial lesions, the etiology of isolated anterior cerebral artery (ACA) territory infarction is not fully elucidated. The purpose of this study was to determine the etiological and clinical characteristics of patients with isolated ...
Bersano A - - 2009
BACKGROUND/PURPOSE: The aim of our study is to evaluate the frequency of aphasia and to describe the characteristics of aphasics among a large sample of acute stroke patients in Italy. METHODS: Out of the 11 572 stroke patients hospitalised within 48 h from stroke onset, included in the PROSIT study, ...
Agrawal Varun - - 2010
BACKGROUND: Thrombolytic therapy is an effective treatment modality for acute ischaemic stroke within 3 hours of symptom onset. Its safety and efficacy have not been studied in patients with chronic kidney disease (CKD), who are known to have abnormalities in coagulation and platelet function. METHODS: We studied all patients who ...
Undas Anetta - - 2010
INTRODUCTION: Hypercoagulable state occurs in patients with acute vascular events. We wondered whether clot structure/function is altered in acute ischemic stroke (AIS), like in acute myocardial infarction. PATIENTS AND METHODS: In 45 consecutive patients with AIS (24M, 21F), aged 67.4+/-10.9 years, and 45 healthy controls matched for age and sex, ...
Ko Youngchai - - 2010
The usefulness of 64-multidetector row computed tomography (MDCT) for the evaluation of aortic atherosclerotic disease (AAD), a potential source of cerebral emboli, has recently been suggested. We aimed to assess the significance of AAD by using MDCT in patients who are suspected to have had embolic stroke clinically or radiologically ...
Telman G - - 2010
BACKGROUND: The transient ischaemic attack (TIA) is accepted as a subtype of resolved ischaemic stroke. In that case, the risk factor profiles as well as the work-up results of TIA and stroke patients should be similar in both groups. Given that such data are limited, we compared the risk factor ...
Patel Dimpi - - 2010
INTRODUCTION: Cerebral thromboembolic event (CTE) is a possible complication of pulmonary vein antrum isolation (PVAI). The objective of this study was to report long-term functional and neurocognitive recovery in patients who had a CTE during or within 48 hours of catheter ablation. METHODS AND RESULTS: We screened 3,060 patients who ...
Isenegger J?rg - - 2010
BACKGROUND:Early classification of ischemic stroke subtype is important for secondary stroke prevention and may guide further investigations. METHODS: Levels of coagulation activation [fibrinopeptide A (FPA), prothrombin fragment 1+2 (F1+2), thrombin-antithrombin complex (TAT)] and fibrinolysis activation [plasmin-alpha(2)-antiplasmin complex (PAP), D-dimers] markers were measured in 98 consecutive patients with a first-ever acute ...
Uchino Ken - - 2010
BACKGROUND: The frequency with which intravenous thrombolysis for acute ischemic stroke results in normal clinical and radiographic status is currently unknown. METHODS: Patients who received intravenous thrombolysis at community hospitals and a stroke center were retrospectively analyzed for occurrence of normal imaging after tissue plasminogen activator (tPA) treatment. The cases ...
Gregoire Simone M - - 2010
BACKGROUND AND PURPOSE: Little is known about the development of cerebral microbleeds in patients with ischemic stroke. We studied the incidence of new microbleeds in a cohort of patients with ischemic stroke or transient ischemic attack screened for microbleeds at baseline. METHODS: Twenty-one surviving patients with ischemic stroke or transient ...
Hannon Niamh - - 2010
Prospective population-based studies are important to accurately determine the incidence and characteristics of stroke associated with atrial fibrillation (AF), while avoiding selection bias which may complicate hospital-based studies. We investigated AF-associated stroke within the North Dublin Population Stroke Study, a prospective cohort study of stroke/transient ischaemic attack in 294,592 individuals, ...
Bandaru V C S Srinivasarao - - 2009
BACKGROUND: Younger patients, aged below 45 years, usually lack the conventional risk factors of stroke whereas infections, especially in developing countries, may play a role. There have been many reports in the last decade about the association of Chlamydia pneumoniae (C. pneumoniae) and atherosclerosis involving cerebral vessels. OBJECTIVE: To investigate ...
De Silva Deidre Anne - - 2009
BACKGROUND: The association of metabolic syndrome (MetS) and intracranial large artery disease (ICLAD) has been described, but only in cohorts of ethnic Korean patients with stroke. We investigated the relationship of MetS and ICLAD among ethnic Chinese patients. METHODS: This is a prospective study of consecutive ethnic Chinese patients with ...
Thoppil Deepu - - 2009
A 29-year-old man, with no significant past medical history, was in his usual state of health until the afternoon of admission. The patient was seated at work eating lunch when he suddenly noticed that his vision became blurry. He covered his right eye and had no visual difficulty but noted ...
Navarro-Sobrino Miriam - - 2009
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is a proinflammatory cytokine with neuroprotective and angiogenic properties demonstrated in animal models of cerebral ischemia but their role in human ischemic stroke is still unknown. Thus, our aim is to determine human GM-CSF plasma level in control subjects and stroke patients and its relationship ...
Galbreath Andrew D - - 2009
We describe a patient in whom dysnomia, ataxia, choreoathetosis, sensory impairment, and severe gait imbalance resulted from an isolated left lentiform nucleus-posterior limb of internal capsule lacunar stroke. Each of these deficits has been described as a consequence of unilateral basal ganglia or internal capsule infarction in prior reports, but ...
Hopps Sarah - - 2009
Atrial fibrillation (AF) results in nearly a quarter of the strokes suffered in patients 80 to 89 years of age. Aspirin and warfarin are primary choices for preventing these ischemic strokes. CHADS2 (Congestive heart failure, Hypertention, Age, Diabetes, Stroke) is a validated assessment tool for cardioembolic stroke in AF. Ischemic ...
Sylaja P N - - 2009
BACKGROUND: In patients with acute stroke receiving intravenous tissue plasminogen activator (tPA), we postulated that the presence of intracranial occlusion on CT angiography (CTA) modifies the benefit of thrombolysis. MATERIALS AND METHODS: Using a retrospective cohort design, we identified patients with acute ischemic stroke in our CTA database between May ...
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