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Sobrino T - - 2010
Growth factors (GF) such as vascular endothelial growth factor (VEGF), angiopoietin-1 (Ang-1) and granulocyte-colony stimulating factor (G-CSF) have been associated with greater efficacy of tissue plasminogen activator (tPA) in experimental studies. To study the association of these GF with arterial recanalization and clinical outcome in patients with acute ischemic stroke ...
Aoki Junya - - 2010
BACKGROUND AND PURPOSE: Although thrombolysis can be performed for acute ischemic stroke (AIS) within 6h of onset, patients with an unknown onset time cannot receive this treatment. The aim of the present study is to investigate a method for determining the onset time of stroke in AIS patients within 24 ...
Glickman Seth W - - 2011
Background: Acute ischemic stroke remains largely a clinical diagnosis. Objective: To assess the potential of several biomarkers to distinguish acute ischemic stroke from mimics in the emergency department (ED). Methods: In this prospective study, 63 patients with suspected acute stroke were enrolled. Blood samples were collected at ED presentation and ...
Sánchez-Perales Carmen - - 2010
Despite the high frequency of cardiovascular disease among the population on dialysis, there are few studies on ischaemic stroke and associated factors. The objective of the present study is to assess the prevalence of ischaemic stroke at the start of dialysis, its incidence in the course of follow-up and possible ...
Stabile Eugenio - - 2010
OBJECTIVES: This single-center registry presents the results of proximal endovascular occlusion (PEO) use in an unselected patient population. BACKGROUND: In published multicenter registries, the use of PEO for carotid artery stenting (CAS) has been demonstrated to be safe and efficient in patient populations selected for anatomical and/or clinical conditions. METHODS: ...
Baker Julie M - - 2010
Recent research suggests that increased left hemisphere cortical activity, primarily of the left frontal cortex, is associated with improved naming performance in stroke patients with aphasia. Our aim was to determine whether anodal transcranial direct-current stimulation (tDCS), a method thought to increase cortical excitability, would improve naming accuracy in stroke ...
Johnson Karin G - - 2010
To determine the frequency of sleep disordered breathing (SDB) in ischemic and hemorrhagic stroke and transient ischemic attack (TIA) patients by meta-analysis. A systematic literature search using Medline, EMBASE and CINAHL and a manual review of references through December 2008 was conducted using specific search terms. The frequency of SDB ...
Ben Assayag Einor - - 2010
To date there is no diagnostic biomarker for mild stroke, although elevation of inflammatory biomarkers has been reported at early stages. Previous studies implicated acetylcholinesterase (AChE) involvement in stroke, and circulating AChE activity reflects inflammatory response, since acetylcholine suppresses inflammation. Therefore, carriers of polymorphisms that modify cholinergic activity should be ...
Karth Abigail - - 2010
Multicomponent dietary weight loss supplements comprise the single largest segment of herbal preparations available to the public. As a result of limited de novo regulatory oversight, supplement-related adverse events are underreported secondary to the lack of adequate pharmacodynamic, pharmacokinetic, and clinical data. Here we report the case of an obese ...
Jiang Thomas T - - 2010
Hemispheric ratios of oxygen extraction fraction (OEF), a proven methodology for the detection of severe hemodynamic impairment and stroke risk, are not sensitive for detecting bilateral hemispheric increases in OEF. The aim of this study was to investigate the use of cerebellum as the reference normal. We analyzed positron emission ...
Doubal F N - - 2010
Lacunar strokes account for 25% of all ischemic strokes and may represent the cerebral manifestation of a systemic small vessel vasculopathy of unknown etiology. Altered retinal vessel fractal dimensions may act as a surrogate marker for diseased cerebral vessels. We used a cross-sectional study to investigate fractal properties of retinal ...
Lin Leng C - - 2011
The measurements for predicting early deterioration of stroke patients is controversial. We studied laboratory measurements and previously identified risk factors to identify factors or predictors of early deterioration after stroke. A prospective observational study of 196 patients with first-time acute ischemic stroke was performed. Demographic data, patient histories, laboratory measurements, ...
Muscal E - - 2010
The most common neurological manifestations of antiphospholipid syndrome (APS) in all age-groups include stroke and transient ischemic attacks due to arterial thromboses and cerebral ischemia. Antiphospholipid antibodies may cause additional non-criteria neurological impairments through vascular, neuroinflammatory and direct neuronal effects. Anti-aggregant or anticoagulant therapies are indicated for APS-related ischemic strokes. ...
Karagiannis Asterios - - 2010
OBJECTIVE: The effect of seasonal variation on the occurrence of stroke remains controversial. The objective of this study was to determine whether there is a seasonal variation in the occurrence of stroke in Northern Greece. METHODS: We recorded the seasonal stroke rates over a 10 year period (from January 1997 ...
Sheu Jau-Jiuan - - 2010
BACKGROUND AND PURPOSE: Case reports or case series have reported the association between hyperthyroidism and cerebrovascular disease. However, hyperthyroidism has never been considered as a potential risk factor for stroke in young people. The aim of the present study is to estimate the risk for ischemic stroke among hyperthyroidism patients ...
Hasan Zeki N - - 2010
OBJECTIVES: To clinically assess neurogenic dysphagia, and to correlate its presence with demographic features, different stroke risk factors, anatomical arterial territorial stroke types, and pathological stroke types. METHODS: Seventy-two stroke inpatients were studied between July 2007 and February 2008, at the Departments of Medicine and Neurology at Al-Yarmouk Teaching Hospital, ...
Mattle H P - - 2010
Patent foramen ovale is found in 24% of healthy adults and 38% of patients with cryptogenic stroke. This ratio and case reports indicate that patent foramen ovale and stroke are associated, probably because of paradoxical embolism. In healthy people with patent foramen ovale, embolic events are not more frequent than ...
Fernandez-Cadenas I - - 2010
BACKGROUND: Despite t-PA proven benefits related to vessel reopening, up to 13% of stroke patients suffer reocclusions after t-PA. We aimed to analyze whether a functional polymorphism in a fibrinolysis inhibitor gene [plasminogen activator inhibitor-1 (PAI-1)] might be associated with reocclusion rates after stroke thrombolytic therapy. METHODS: 165 patients with ...
Horv?th Eszter - - 2010
Lipids have important functions in the human body, but high serum cholesterol level is an important risk factor for cardiovascular and cerebrovascular diseases. Prevention of stroke includes modifying risk factors, like dyslipidemias. Based on this theory, we examined in practice the possible role of a public care neurology and stroke ...
Lin Chorng-Horng - - 2010
OBJECTIVE: Studies on animal models have shown that apoptosis plays a role in acute ischemic stroke, but the clinical significance of apoptosis in human stroke has not been well established. DESIGN AND METHODS: Acute ischemic stroke patients who had been examined by magnetic resonance imaging (MRI) were recruited, and their ...
Strzelczyk Adam - - 2010
Ischemic and hemorrhagic strokes are established etiological factors for recurrent seizures. Still, only few prospective data are available to predict post-stroke epilepsy and to choose the best point in time and anticonvulsive agent for treatment. In a prospective study we evaluated 264 consecutive stroke patients and assessed their post-stroke epilepsy ...
Tseng Kuan-Yin - - 2010
Chorea that occurs as a result of a stroke is rare. We report a patient who developed hemiplegia following an acute hemorrhagic stroke in the left cerebral peduncle and subthalamus; although he had recovered gradually from the severe limb weakness, monochorea occurred 6 months later. Pallidotomy eliminated this symptom and ...
Lu Tung-Wu - - 2010
With the advances in stroke care, the number of high-functioning patients after stroke is increasing. However, existing clinical tools may not be sensitive enough to identify the residual deficits in these patients. The current study aimed to investigate the control of the pelvis, and the joints and end-point of the ...
Ishii Fumiyasu - - 2010
BACKGROUND: : Stroke patients experience postural instability that can impede functional improvements in their gait. However, the precise functions of the dominant and non-dominant hemispheres in controlling static standing posture and weight-bearing remain unclear. OBJECTIVE: : To investigate differences in balancing ability between right-handed patients with right and left hemispheric ...
Prabhakaran Shyam - - 2010
To determine whether warfarin-treated patients with an international normalized ratio less than 1.7 who receive intravenous tissue plasminogen activator for acute ischemic stroke are at increased risk for symptomatic intracerebral hemorrhage. Retrospective study. Academic hospital. Consecutive patients with acute ischemic stroke who are treated with intravenous tissue plasminogen activator. Symptomatic ...
Palazzo Paola - - 2010
BACKGROUND: Transcranial Doppler (TCD) studies demonstrated that cerebral vasomotor reactivity (VMR) can predict the outcome of carotid artery occlusion (CAO). Near-infrared spectroscopy (NIRS) is a non-invasive optical method for assessing hemoglobin (Hb) oxygenation parameters. The purpose of this study was to evaluate the role of NIRS parameters as prognostic markers ...
Ahmad Omar - - 2010
Both transthoracic (TTE) and transoesophageal (TOE) echocardiography are used routinely to investigate ischaemic stroke. We retrospectively assessed the incidence of abnormalities on TTE/TOE and whether an abnormal TTE/TOE result could have been predicted on the basis of ancillary tests and clinical cardiological examination. Data from 428 patients were analysed. The ...
Brouns Raf - - 2010
BACKGROUND: Although uric acid (UA) is one of the most important antioxidants in plasma and appears to be neuroprotective in animal models, results from human studies are controversial. In this study, we investigated the kinetics of serum UA concentrations in the acute, subacute and chronic phase of ischemic stroke and ...
De Reuck Jacques - - 2010
BACKGROUND AND PURPOSE: Migraine with aura (MA) is considered as a risk factor for ischaemic stroke. The present observational retrospective study compares migraine patients admitted for a documented stroke with those presenting focal neurological symptoms and headache without a demonstrable lesion and in which the final diagnosis was a migraine ...
Shiber Joseph R - - 2010
BACKGROUND: Epidemiologic studies of stroke in the 1970s and 1980s have reported the percentage of ischemic stroke as 73% to 86%, with hemorrhagic stroke as only 8% to 18%; the remainder was undetermined (due to not performing computed tomographic [CT] scanning or an autopsy). In our clinical work, it appeared ...
Chau Anson C M - - 2010
Acupuncture is used as a treatment in stroke patients with aphasia, yet the underlying neural mechanisms are unknown. This study aims to examine the relationship between changes in language function and brain activation using functional magnetic resonance imaging in chronic stroke patients with aphasia who underwent an 8-week acupuncture protocol. ...
Ariës M J H - - 2010
BACKGROUND AND PURPOSE: Whether leukoaraiosis on baseline CT is associated with an increased risk of symptomatic intracerebral haemorrhage (sICH) or poor outcome following tissue plasminogen activator (tPA) treatment for acute ischaemic stroke is still a matter of debate. OBJECTIVE: To investigate the relationship between the presence and severity of leukoaraiosis ...
Samiullah Shaikh - - 2010
OBJECTIVE: To observe frequency of various causes of stroke in patients of young (15-35 years) age. METHODS: This Descriptive case series study was conducted in all Medical Units of Liaquat University Hospital (LUH) Jamshoro, Hyderabad, from August 2006 to February 2008 and included 50 patients of stroke aged 15-35 years, ...
Broniatowski Michael - - 2010
We undertook to determine whether paced vocal fold adduction can check aspiration in patients with various neurologic conditions. Five patients with fluoroscopically documented aspiration and repeated pneumonias were enrolled. Two previously reported patients with hemispheric stroke were compared to 3 additional subjects with brain stem-basal ganglia and cerebellar stroke, cerebral ...
Etgen Thorleif - - 2010
Bilateral superior altitudinal hemianopia is an uncommon clinical presentation of ischemic stroke. We report a patient who had an ischemic stroke with a pure bilateral superior altitudinal hemianopia resulting from bilateral ischemia in the optic radiation. This symptom was first overlooked and a delusion was suspected. A thorough clinical examination ...
Spengos Konstantinos - - 2010
Cardioembolism is the most frequent cause of ischemic stroke in Greece. However, data regarding this stroke subtype in young adults from Greece and the East Mediterranean area are scarce. We aimed to determine the source of embolism and evaluate outcomes in a sample of young Greek patients with ischemic stroke ...
Comolli Lorenzo - - 2010
Functional electrical stimulation (FES) is a well established method in the rehabilitation of stroke patients. Indeed, a bilateral movement such as cycling induced by FES would be crucial for these patients who had an unilateral motor impairment and had to recover an equivalent use of limbs. The aim of this ...
Stamenova Vessela - - 2010
The study investigated performance on pantomime and imitation of transitive and intransitive gestures in 80 stroke patients, 42 with left (LHD) and 38 with right (RHD) hemisphere damage. Patients were also categorized in two groups based on the time that has elapsed between their stroke and the apraxia assessment: acute-subacute ...
Roffe Christine - - 2010
OBJECTIVE: Sleep disordered breathing is common in patients with cerebrovascular disease. Nocturnal hypoxia may lead to daytime tiredness and cognitive impairment, thus affecting progress. This study assessed the prevalence of nocturnal hypoxia during rehabilitation from stroke. DESIGN: Prospective observational trial. SETTING: The stroke rehabilitation wards of the North Staffordshire Hospital, ...
Tong D M - - 2010
Despite evidence from clinical and population studies, the aim of the present study was to suggest that multiple factors contribute to periodic breathing (PB). However, little information has been focused on episodes of tracheobronchial infections (TBI) preceding PB onset. Thirty subjects with acute stroke who had PB and 41 subjects ...
Azarpazhooh Mahmoud Reza - - 2010
Serum heat shock protein 27 immunoglobulin G (IgG) antibody titers (anti-HSP27) and high-sensitivity C-reactive protein (hsCRP) concentrations were measured in samples from 168 patients in the first 24 hours after the onset of stroke and 80 age-and sex-matched control participants. In patients with stroke, median serum anti-HSP27 titer was significantly ...
Fazio Giovanni - - 2010
According to the current guidelines, the patent foramen ovale (PFO) is still considered a qualitative factor and, as a consequence, its closure is recommended just on the basis of its 'presence'. In the year 2008, we evaluated 25 patients (mean age 62.7) with acute cerebrovascular event and 92 patients (mean ...
De Reuck Jacques - - 2010
BACKGROUND AND OBJECTIVES: Early intravenous treatment with recombinant tissue plasminogen activator (rt-PA) improves the outcome of patients with an acute ischemic stroke. This retrospective observational study analyses whether rt-PA treatment also prevents the occurrence of early- and late-onset seizures. PATIENTS AND METHODS: Thirty-eight patients treated with rt-PA were compared to ...
Page Stephen J - - 2010
BACKGROUND AND PURPOSE: Conventional electrical stimulation modalities are limited by their lack of opportunities for motor learning and, consequently, their impact on function. Other rehabilitative regimens necessitate affected hand and wrist movement for patients to be included, making them implausible for most patients. In light of these challenges, the current ...
Man B L - - 2010
BACKGROUND AND PURPOSE: Coexisting ischemic heart disease (IHD) and concurrent atherosclerosis of intracranial and extracranial vessels is common in Asians. This study aims to investigate the long-term outcomes of ischemic stroke patients with concurrent stenoses and IHD. METHODS: This was a prospective cohort study in Hong Kong. Consecutive Chinese patients ...
van Swigchem Roos R Department of Rehabilitation Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The - - 2010
The aim of this study was to evaluate whether community-dwelling chronic stroke patients wearing an ankle-foot orthosis would benefit from changing to functional electrical stimulation of the peroneal nerve. In 26 community-dwelling chronic (> 6 months post-onset) patients after stroke, their ankle-foot orthosis was replaced by a surface-based functional electrical ...
Baptista Miguel Viana - - 2010
BACKGROUND AND PURPOSE: Fabry disease is an X-linked monogenic disorder caused by mutations in the GLA gene. Recent data suggest that stroke in young adults may be associated with Fabry disease. We aimed to ascertain the prevalence of this disorder among young adult patients with stroke in Portugal by GLA ...
Kuwashiro Takahiro - - 2010
BACKGROUND: Atheromatous plaques of the aortic arch that extend to the origin of its branches may cause stroke. The frequency and clinical implications of plaque at the origin of the left subclavian artery (LSCA) in patients with recent ischemic stroke were investigated. METHODS: We studied 347 consecutive patients (223 men, ...
Ferrari J - - 2010
OBJECTIVE: TIA is associated with a substantial short-term risk of stroke and is thus increasingly recognized as an unstable condition necessitating full medical attention. Our study sought to assess the rate of and predictors for early deterioration after TIA or minor stroke in a large nationwide survey among Austrian stroke ...
Seo Han Gil - - 2011
The purpose of this study was to evaluate longitudinal changes of the swallowing process in stroke patients with aspiration using kinematic analysis. Twenty-eight subacute stroke patients with aspiration on fluid at initial videofluoroscopic swallowing studies (VFSS) were included. Follow-up VFSS was performed at 2-4 weeks after initial studies that were conducted ...
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