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Nascimento M M MM Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Stockholm, - - 2014
Osteoprotegerin (OPG) regulates bone mass by inhibiting osteoclast differentiation and activation, and plays a role in vascular calcification. We evaluated the relationship between osteoprotegerin levels and inflammatory markers, atherosclerosis, and mortality in patients with stages 3-5 chronic kidney disease. A total of 145 subjects (median age 61 years, 61% men; ...
Nascimento M M MM Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Stockholm, - - 2014
Osteoprotegerin (OPG) regulates bone mass by inhibiting osteoclast differentiation and activation, and plays a role in vascular calcification. We evaluated the relationship between osteoprotegerin levels and inflammatory markers, atherosclerosis, and mortality in patients with stages 3-5 chronic kidney disease. A total of 145 subjects (median age 61 years, 61% men; ...
Wen Zhengwei - - 2014
The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic gastritis and ...
Fitzsimmons Jennifer J Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women׳s Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: - - 2014
The goal of this study was to assess integrity of the cingulum bundle in patients diagnosed with first episode schizophrenia, chronic schizophrenia, and matched controls as well as to determine the relationship between diffusion measures of cingulum bundle integrity and severity of patients׳ delusions of reference. Participants, who comprised 18 ...
Lee Dong Hoon DH Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, - - 2014
This study was conducted to present the clinical outcome of invasive fungal sinusitis of the sphenoid sinus and to analyze clinical factors influencing patient survival. A retrospective review of 12 cases of invasive fungal sphenoiditis was conducted. Cases were divided into acute fulminant invasive fungal spheonoidits (n=4) and chronic invasive ...
Billah M M MM Dr Mallick Masum Billah, OSD, DGHS, In Attachment to Institute of Epidemiology, Disease Control and Research (IEDCR), Mohakhali, Dhaka, - - 2014
An observational cross-sectional study of 50 cases of chronic calcific pancreatitis patients was conducted in Bangabandhu Sheikh Mujib Medical University (BSMMU) and some other tertiary level hospitals of Dhaka city from August 2008 to July 2010. Patients required laparotomy for different modalities of surgical treatment to manage chronic calcific pancreatitis ...
Musalaiah S V V S SV Department of Periodontics, St Joseph Dental College, Duggirala, Eluru, Andhra Pradesh, - - 2014
Periodontal tissues mount an immune inflammatory response to bacteria and their products. Certain inflammatory cytokines produced during periodontal inflammation increase the production of acute phase proteins like high‑sensitivity C‑reactive protein (hs‑CRP) and can depress erythropoietin production leading to the development of anemia. The aim of this study is to investigate ...
Hirano Kenji K Department of Gastroenterology, The University of Tokyo Graduate School of Medicine, Tokyo, - - 2014
To determine the nutritional markers important for assessing the degree of pancreatic insufficiency due to chronic pancreatitis in routine clinical practice. A total of 137 patients with chronic pancreatitis were followed up for more than 1 year. They were divided into two groups: a pancreatic diabetes mellitus (DM) group, consisting ...
Alshehry Nawal F NF Princess Margaret Cancer Centre Toronto, Ontario, Canada ; Queens University Kingston, Ontario, - - 2014
Gastric antral vascular ectasia (GAVE) has been reported very rarely in imatinib-treated gastrointestinal stromal tumor (GIST) and scleroderma/pulmonary hypertension patients. We present the first report of a case of GAVE in a chronic myeloid leukemia (CML) patient after treatment with imatinib. This diagnosis should be considered in CML patients with ...
Hammoud D D Oklahoma University Health Sciences Centre, 1100 N Lindsay, Oklahoma City, Oklahoma 73104, USA. - - 2014
Vitamin A toxicity is a well-described medical condition with a multitude of potential presenting signs and symptoms. It can be divided into acute and chronic toxicity. Serum vitamin A concentrations are raised in chronic renal failure even with ingestion of less than the usual toxic doses. Hypercalcaemia can occasionally be ...
Dao Kim-Hien T KH Oregon Health and Sciences University, Knight Cancer Institute, Hematology and Medical Oncology, Portland, OR, - - 2014
Mutations in CSF3R (colony-stimulating factor 3 receptor) are frequent oncogenic drivers in chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). Here we describe a 75 year old man who was diagnosed with CSF3R-T618I-positive atypical CML. He presented with leukocytosis, anemia, and thrombocytopenia and developed massive splenomegaly and severe ...
Bilic Ante - - 2014
Portal vein in healthy subjects and in patient with chronic diffuse liver disease was investigated by the combination of real-time technique and Doppler impulsive system. Control group consisted of 99 healthy subjects of median age of 36,8, and with life raging span from 14 to 77 yrs. Experimental group consisted ...
Bacci Mr M Department of General Practice, Faculdade de Medicina do ABC (ABC Medical School), Santo André, - - 2014
Although the association between chronic kidney disease and dyspepsia is widely known, it remains poorly investigated. Among the types of gastric inflammation that lead to symptoms, erosive antral gastritis is the most common form. A direct correlation between the urea serum levels and the time in hemodialysis with the onset ...
Siddique Iqbal I Department of Medicine, Faculty of Medicine, Kuwait University, P. O. Box 24923, 13110 Safat, Kuwait ; Thunayan Al-Ghanim Gastroenterology Center, Al-Amiri Hospital, Sharq, - - 2014
The varied clinical presentations of Helicobacter pylori (H. pylori) infection are most likely due to differences in the virulence of individual strains, which determines its ability to induce production of interleukin-8 (IL-8) in the gastric mucosa. The aim of this study was to examine association between cagA, vacA-s1 and vacA-s2 ...
Nadri Quaid Q Department of Medicine, Section of Nephrology, King Faisal Specialist Hospital and Research Center, Riyadh, Ar-Riyadh, Saudi - - 2014
Drug-induced interstitial nephritis is a common cause of acute kidney injury indicated by elevated serum creatinine. We report a case of omeprazole-induced acute granulomatous interstitial nephritis (GIN). Our patient developed acute GIN secondary to omeprazole ingestion requiring haemodialysis. Treatment with steroids and withdrawal of omperazole was successful allowing the patient ...
Berezin Alexander E AE State Medical University, Internal Medicine Department, Zaporozhye, - - 2014
Serum uric acid (SUA) is considered a marker for natural progression of chronic heart failure (CHF) mediated cardiovascular remodelling. CHF associates with declining of circulating mononuclear progenitor cells (MPCs). The objective of this study was to evaluate the interrelationship between SUA concentrations and proangiogenic MPCs in ischemic CHF patients. The ...
Park HeeKuk H Department of Microbiology, College of Medicine, Chung-Ang University, Seoul, South - - 2014
Respiratory infections are well-known triggers of chronic respiratory diseases. Recently, culture-independent tools have indicated that lower airway microbiota may contribute to pathophysiologic processes associated with asthma and chronic obstructive pulmonary disease (COPD). However, the relationship between upper airway microbiota and chronic respiratory diseases remains unclear. This study was undertaken to ...
Appa Suri N SN Department of Ophthalmology, Kaiser Permanente, Yorba Linda, - - 2014
To describe a case of a patient with chronic central serous chorioretinopathy who was found to have an adrenocorticotropin-secreting pituitary microadenoma despite the absence of many clinical signs of Cushing syndrome. A retrospective chart review was performed. This study included a 42-year-old white woman with a history of chronic central ...
Grünert Sarah C SC Center of Pediatrics and Adolescent Medicine, University Hospital Freiburg, Freiburg, Germany. - - 2014
Multiple acyl-CoA dehydrogenase deficiency (MADD) is an autosomal recessive disorder caused by deficiency of electron transfer flavoprotein or electron transfer flavoprotein dehydrogenase. The clinical picture of late-onset forms is highly variable with symptoms ranging from acute metabolic decompensations to chronic, mainly muscular problems or even asymptomatic cases. All 350 cases ...
Chen Yu-Chen YC Department of Radiology, Jiangsu Key Laboratory of Molecular and Functional Imaging, Zhongda Hospital, Medical School, Southeast University, Nanjing, - - 2014
The neural mechanisms that give rise to the phantom sound of tinnitus are poorly understood. This study aims to investigate whether aberrant spontaneous brain activity exists in chronic tinnitus patients using resting-state functional magnetic resonance imaging (fMRI) technique. A total of 31 patients with chronic tinnitus patients and 32 healthy ...
Wierzbicka Małgorzata M Department of Otolaryngology, Head and Neck Surgery, Poznań University of Medical Sciences, Poznań, - - 2014
Background Shear wave elastography (SWE) is widely used in breast, liver, prostate and thyroid evaluations. Elastography provides additional information if used to assess parotid gland pathology. We assessed parotid glands by means of SWE to compare the parenchyma properties in different types of inflammation. Material and Methods Prospective analysis included ...
Xiang Daijun D Department of Clinical Laboratory, Chinese People's Liberation Army General Hospital Beijing 100853, - - 2014
A revised classification of chronic kidney disease (CKD) was proposed by the Kidney Disease: Improving Global Outcomes (KDIGO) in 2012. Neutrophil gelatinase-associated lipocalin (NGAL) was considered as one of the most promising biomarkers in clinical nephrology. The aim of this study was to examine the level of NGAL in patients ...
Donen Anna A Department of Radiology, Hillingdon Hospital, Uxbridge, Middlesex, UK - - 2014
Chronic acalculous cholecystits typically presents with biliary symptoms, normal blood tests and unremarkable ultrasound, computerized tomography and magnetic resonance cholangiopancreatography. However, cholescintigraphy may show reduced gallbladder ejection fraction (GBEF). There are no reports on using ultrasound to measure GBEF in adults. Twenty-eight patients with the above presentation underwent ultrasound before ...
Ali Asghar - - 2013
Low back pain with or without lower extremity pain is the most common problem among chronic pain disorders with significant economic, social, and health impact. This study was conducted to determine the frequency of lumbar disc herniation and its different levels, among patients with chronic backache. This cross sectional study ...
Trifa Adrian P AP Department of Medical Genetics, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6, Pasteur Street, 400349 Cluj-Napoca, - - 2014
The coexistence of both myeloproliferative and lymphoproliferative neoplasms in the same patient is an uncommon finding. We report two patients who presented such an association. The first patient was initially diagnosed with essential thrombocythemia, developing a clinical and haematological picture consistent with chronic lymphocytic leukaemia several years afterwards. The second ...
Rikimaru Mitsue - - 2012
Post-transcriptional taurine modification at the first anticodon ("wobble") nucleotide is deficient in A3243G-mutant mitochondrial (mt) tRNA(Leu(UUR)) of patients with myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). Wobble nucleotide modifications in tRNAs have recently been identified to be important in the accurate and efficient deciphering of codons. We herein examined ...
Ibrahim Ibrahim - - 2011
INTRODUCTION: Modulation of neurodegeneration by physical activity is an active topic in contemporary research. The purpose of this study was to investigate changes in the brain's microstructure in multiple sclerosis (MS) after facilitation physiotherapy. METHODS: Eleven patients with MS were examined using motor and neuropsychological testing and multimodal MRI at ...
De Ciuceis Carolina - - 2011
Structural alterations of subcutaneous small resistance arteries, as indicated by an increased media:lumen ratio, are frequently present in hypertensive and/or diabetic patients and may represent the earliest alteration observed. In addition, media:lumen ratios of small arteries have a strong prognostic significance. However, no data are available about the structure of ...
Maksud Fabiana A N - - 2011
Background: Ghrelin is a peptide secreted mainly by gastric mucosa, and has been implicated in the regulation of eating behavior and weight balance. Obesity and H. pylori infection are associated with changes in plasma ghrelin levels. Objective: This study was designed to evaluate the density of ghrelin-producing cells in the ...
Fathi Mina - - 2011
The soluble forms of Fas and its ligand (sFas and sFasL) correlate with disease progression in various malignancies. We compared serum levels of sFas and sFasL in children with acute lymphoblastic leukemia and healthy children to determine the prognostic significance of these molecules. Serum levels of sFas and sFasL were ...
Mitter Diana - - 2011
Patients with an interstitial 13q deletion that contains the RB1 gene show retinoblastoma and variable clinical features. Relationship between phenotypic expression and loss of specific neighboring genes are unresolved, yet. We obtained clinical, cytogenetic and molecular data in 63 patients with an interstitial 13q deletion involving RB1. Whole-genome array analysis ...
Bond David J - - 2011
BACKGROUND: Compared with normal-weight patients, obese patients with bipolar I disorder (BD) suffer more manic and depressive episodes and make more suicide attempts. In the general population, obesity is associated with reduced total brain volume (TBV) and gray matter volume (GMV), but the neurobiology of obesity in BD has not ...
Lassailly Guillaume - - 2011
BACKGROUND: Liver biopsy is considered as the gold standard for assessing nonalcoholic fatty liver disease (NAFLD) histologic lesions in patients with morbid obesity. The aim of this study was to determine the diagnostic utility of noninvasive markers of fibrosis (FibroTest), steatosis (SteatoTest), and steatohepatitis (NashTest, ActiTest) in these patients. MATERIALS ...
Liu Hao - - 2011
BACKGROUND: Obesity and decreased kidney function have been shown to be prevalent in Western patients with heart failure; however, whether this phenomenon exists in Chinese patients with chronic heart failure (CHF) is not known. METHODS AND RESULTS: One thousand and nine patients with CHF from the China Heart Survey were ...
Arango Celso - - 2011
The objective of this study was to compare coronary heart disease (CHD) risk and metabolic syndrome (MS) prevalence in patients with deficit (DS) and non-deficit schizophrenia treated with antipsychotics. A total of 1452 antipsychotic-treated outpatients meeting criteria for schizophrenia, schizophreniform or schizoaffective disorder were included in this cross-sectional multicentre study. ...
Chatzikonstantinou Anastasios - - 2011
Patients with cardioembolic ischemic stroke from nonvalvular atrial fibrillation (NVAF) are candidates for long-term anticoagulation. This study examines the prevalence of cerebral microbleeds (MBs) in stroke patients with NVAF. A total of 132 consecutive ischemic stroke patients with NVAF admitted to our Stroke Unit were recruited if complete magnetic resonance ...
Amine Bouchra - - 2011
OBJECTIVE: We aimed to estimate the prevalence of overweight among Moroccan children and adolescents with juvenile idiopathic arthritis (JIA). METHODS: Fifty-eight patients with JIA according to the International League of Association of Rheumatology (ILAR) criteria were included consecutively in this study. The median age of patients was 11±3.3years (range 2-16). ...
Dean Steven M - - 2011
BACKGROUND: Previous reports regarding elephantiasis nostras verrucosa (ENV) have been typically limited to 3 or fewer patients. OBJECTIVES: We sought to statistically ascertain what demographic features and clinical variables are associated with ENV. METHODS: A retrospective chart review of 21 patients with ENV from 2006 to 2008 was performed and ...
Merle J V - - 2011
BACKGROUND: An imbalance in appetite-regulating neuropeptides of the central nervous system has been associated with anorexia nervosa (AN), but the mechanisms of action are poorly understood. Agouti-related protein (AGRP), an orexigenic mediator of the hypothalamus, increases food intake and decreases energy expenditure in times of negative energy balance. The aim ...
Ersöz Feyzullah - - 2011
BACKGROUND: Visceral obesity is one of the main components of the metabolic syndrome (MetS). The retroperitoneal fat area (RFA) is part of the intraabdominal adipose mass. The aim of this clinical trial was to determine whether there is an association between the RFA measurement and MetS components in patients undergoing ...
Biere-Rafi S - - 2011
Summary.  Obesity is a major health concern not only in the general population but also in patients with haemophilia. Little is known about the consequences of obesity for haemophilia patients. As obesity is an important risk factor for osteoarthritis, these effects may be even more pronounced in haemophilia patients who ...
Aghdassi Elaheh - - 2011
Introduction: Circulating fatty acids (FAs) may play a role in the disease pathogenesis of patients with systemic lupus erythematosus (SLE). Objectives: To compare red blood cell (RBC) and plasma FA composition: (1) between female SLE patients and age-matched healthy female (HF) controls and in SLE with history of cardiovascular disease ...
Katsaros K M - - 2011
Percutaneous coronary intervention (PCI) represents the most important treatment of coronary artery stenosis today. But instent restenosis (ISR) is a limitation for the outcome. Fas and Fas Ligand have been implicated in apoptosis and vessel wall inflammation. Their role in ISR is not known so far. In this prospective study ...
Wu Chia-Chun - - 2011
BACKGROUND: Five components of metabolic syndrome (MetS) have been identified as predictive of cardiovascular events (CVEs) in the general population: impaired fasting glucose, abdominal obesity, hypertriglyceridemia, hypertension and low high-density lipoprotein cholesterol. Whether MetS and its components are also predictive of CVEs in chronic hemodialysis (HD) patients remains unclear. We ...
Hamdy Nadia M - - 2011
This researcher previously found that serum levels of some inflammatory cytokines are elevated in patients with cardiovascular disease (CVD). Hence, this study investigated the relationship between circulating levels of pro-anti-inflammatory cytokines, T-cell activation marker and carbohydrate antigen 125 (CA 125) for the first time in obese Egyptian patients with heart ...
Kim W H - - 2011
BACKGROUND: /st> This study was performed to assess whether intubation is more difficult in obese patients and to assess the ability of a new index: the ratio of the neck circumference to thyromental distance (NC/TM), to predict difficult intubation in obese patients. METHODS: /st> The incidence of difficult tracheal intubation ...
Lauffer Adriana - - 2011
BACKGROUND: The link between diabetes mellitus and gastroesophageal reflux disease (GERD) is controversial. We assessed the relationship between glycemic control (GC) and GERD in morbidly obese patients. METHODS: Consecutive patients with morbid obesity (n = 86) underwent manometry, pH-metry, endoscopy, and contrasted X-ray after responding to a GERD questionnaire and dosing fasting ...
Makino Takahiro - - 2011
OBJECTIVE: Pathological studies showed both pontine transverse (cortico-ponto-cerebellar) and longitudinal (corticospinal) fibers degenerate in MSA. The objective was to investigate the association between the development of cross sign, degenerations of pontine fibers, and the frequency of pyramidal signs in MSA. METHODS: Patients with MSA (n=26) and healthy subjects (n=27) were ...
Sipola Petri - - 2011
Venous thromboemboli can cause both pulmonary embolism (PE) and paradoxical embolism in the presence of a cardiac right-to-left shunt. Our aim was to prospectively assess the prevalence of PE in patients with ischemic stroke with suspected cardiogenic etiology and thereby to clarify the possible role of paradoxical embolism as a ...
Hanson E - - 2011
Summary.  Background: Compared with coronary artery disease, there are few studies on von Willebrand factor (VWF) in ischemic stroke (IS). Moreover, there is little information on VWF in the etiologic subtypes of IS. Objectives: The aim of the present study was to investigate VWF in IS and in the etiologic subtypes ...
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